Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
2,2'-(1,4-Phenylene)bis-1H-benzimidazole is an intermediate in the synthesis of a water-soluble organic compound that is added to sunscreens to absorb UVA rays. Group: Biochemicals. Grades: Highly Purified. CAS No. 1047-63-8. Pack Sizes: 1g, 2.5g. Molecular Formula: C20H14N4. US Biological Life Sciences.
2-[[[4- (Aminoiminomethyl) phenyl]amino]methyl]-1-methyl-1H-benzimidazole-5-carboxylic Acid Ethyl Ester Hydrochloride is derived from Dabigatran (D100090), which is a non-peptide, direct thrombin inhibior and anti-thrombotic. Group: Biochemicals. Grades: Highly Purified. CAS No. 1422435-39-9. Pack Sizes: 10mg, 50mg. Molecular Formula: C19H21N5O2; (HCl), Molecular Weight: 351.403645999999. US Biological Life Sciences.
2- [ [ [4- [ (Z) -Amino [ [ (hexyloxy) carbonyl] imino] methyl] phenyl] amino] methyl] -1-methyl-1H-benzimidazole-5-carboxylic Acid is a degradation product of Dabigatran (D100090). which is a drug that is a nonpeptide, direct thrombin inhibitor and an antithrombotic. Group: Biochemicals. Grades: Highly Purified. CAS No. 1848337-06-3. Pack Sizes: 5mg, 25mg. Molecular Formula: C24H29N5O4, Molecular Weight: 451.52. US Biological Life Sciences.
2-(Benzoylamino)-1-(3-phenylpropyl)-1H-benzimidazole-5-carboxylic Acid is a small molecule that has been reported as a novel histone methyltransferase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1374601-41-8. Pack Sizes: 1mg, 5mg. Molecular Formula: C24H21N3O3, Molecular Weight: 399.44. US Biological Life Sciences.
Worldwide
2-(Methoxymethyl)-5-(phenylthio)-1H-benzimidazole
2-(Methoxymethyl)-5-(phenylthio)-1H-benzimidazole. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1H-Benzimidazole, 2-(methoxymethyl)-5-(phenylthio)- (9CI),1H-Benzimidazole, 2-(methoxymethyl)-6-(phenylthio)-, 2-(Methoxymethyl)-5-(phenylthio)-1H-benzimidazole. CAS No. 92114-71-1. Pack Sizes: 10MG. IUPAC Name: 2-(methoxymethyl)-5-phenylsulfanyl-1H-benzimidazole. Molecular Formula: C15H14N2OS. Mole Weight: 270.35. Catalog: APS92114711. SMILES: COCc1nc2cc(Sc3ccccc3)ccc2[nH]1. Format: Neat. Shipping: Room Temperature.
2-Phenoxymethyl-7-phenylmethoxy-1H-benzimidazole
A 2-substituted benzimidazole as inhibitor of cell-free RBL-1-5-lipoxygenase. Group: Biochemicals. Grades: Highly Purified. CAS No. 1215342-45-2. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
2-Phenyl-1H-benzimidazole
2-Phenyl-1H-benzimidazole is areagent used in the synthesis of various aryl-substituted benzimidazole derivatives. Also used in the synthesis of benzimidazole and quinocaline derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 716-79-0. Pack Sizes: 5g, 25g. Molecular Formula: C13H10N2. US Biological Life Sciences.
Worldwide
2-Phenyl-5-Benzimidazolesulfonic Acid
2-Phenyl-5-Benzimidazolesulfonic Acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 27503-81-7. Pack Sizes: 10g, 25g, 50g, 100g, 250g. US Biological Life Sciences.
Worldwide
2-Phenylbenzimidazole
2-Phenylbenzimidazole. Group: Ligands for functional metal complexes. CAS No. 716-79-0. Product ID: 2-phenyl-1H-benzimidazole. Molecular formula: 194.23g/mol. Mole weight: C13H10N2. C1=CC=C(C=C1)C2=NC3=CC=CC=C3N2. InChI=1S/C13H10N2/c1-2-6-10 (7-3-1)13-14-11-8-4-5-9-12 (11)15-13/h1-9H, (H, 14, 15). DWYHDSLIWMUSOO-UHFFFAOYSA-N. 97%.
A cell-permeable benzimidazole that, in addition to its inhibitory potency against luciferase activity (IC50 <10nM), also activates AMPK signaling by increasing cellular ADP/ATP ratio via mitochondria respiration upcoupling, effectively activating AMPK & PGC-1alpha in muscle, but not liver, cell types both in cultures (5-20uM in rat L6 myotubes) in vitro and in db/db mice (15mg/kg/day via p.o.) in vivo. Reported to improve glucose and insulin tolerance of db/db mice without any apparent effects on body weight or food intake. Group: Biochemicals. Grades: Highly Purified. CAS No. 4529-96-8. Pack Sizes: 25mg. Molecular Formula: C??H??N?. US Biological Life Sciences.
An anthelmintic drug belonging to the benzimidazole group mainly used for the treatment of pinworm in animals. Recently, fenbendazole has been shown to selectively induce cytotoxicity in cancer cells via impairment of proteasomal function and induction of unfolded protein response. Group: Biochemicals. Grades: Highly Purified. CAS No. 43210-67-9. Pack Sizes: 100mg. US Biological Life Sciences.
1, ?2-?Piperidinedicarboxyl ?ic Acid 1-?(Phenylmethyl) Ester is used to prepare disubstituted azetidinones as selective inhibitors of cysteine protease cathepsin K. It is also used to synthesize 2-?[(R)?-?2-?methylpyrrolidin-?2-?yl]?-?1H-?benzimidazole-?4-?carboxamide (ABT-?888) as the Poly(ADP-?ribose) Polymerase (PARP) inhibitor for the treatment of cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 28697-07-6. Pack Sizes: 25g, 100g. Molecular Formula: C14H17NO4, Molecular Weight: 263.29. US Biological Life Sciences.
1H-1-Ethyl Candesartan Cilexetil. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-[[(Cyclohexyloxy)carbonyl]oxy]ethyl 2-ethoxy-1-[[2'-(1-ethyl-1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylate,1H-Benzimidazole-7-carboxylic acid, 2-ethoxy-1-[[2'-(1-ethyl-1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, 1-[[(cyclohexyloxy)carbonyl]oxy]ethyl ester, Candesartan Cilexetil Imp. E (EP). CAS No. 914613-35-7. IUPAC Name: 1-cyclohexyloxycarbonyloxyethyl 2-ethoxy-3-[[4-[2- (1-ethyltetrazol-5-yl) phenyl]phenyl]methyl]benzimidazole-4-carboxylate. Molecular Formula: C35H38N6O6. Mole Weight: 638.71. Catalog: APS914613357. SMILES: CCOc1nc2cccc (C (=O)OC (C)OC (=O)OC3CCCCC3)c2n1Cc4ccc (cc4)c5ccccc5c6nnnn6CC. Format: Neat.
2,?3-?Diaminobenzamide Dihydrochloride
2,?3-?Diaminobenzamide Dihydrochloride can be used in synthesis and evaluation of (heteroaryl phenyl ) benzimidazolecarboxami de s as orally efficacious poly(ADP-ribose) polymerase-1 inhibitors and anticancer agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 266993-72-0. Pack Sizes: 25mg, 50mg. Molecular Formula: C7H9N3O; 2(HCl), Molecular Weight: 151.1723646. US Biological Life Sciences.
Worldwide
2-Amino-5 (6) - [α -hydroxybenzyl] benzimidazole
The major urinary metabolite of Mebendazole in man. Group: Biochemicals. Alternative Names: 2-Amino-α-phenyl-1H-benzimidazole-6-methanol; 2-Amino-α-phenyl-1H-benzimidazole-5-methanol. Grades: Highly Purified. CAS No. 75501-05-2. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
2-Amino-5-benzoyl-1-methylbenzimidazole
Mebendazole thermal decomposition product. Mebendazole impurity. Group: Biochemicals. Alternative Names: (2-Amino-1-methyl-1H-benzimidazol-5-yl)phenylmethanone; 1-Methyl-2-amino-5-benzoyl-(1H)benzimidazole. Grades: Highly Purified. CAS No. 66066-76-0. Pack Sizes: 50mg. US Biological Life Sciences.
Versatile Ligand for the Pd-catalyzed coupling of secondary arylamines and alkylamines. Ligand used for the Pd-catalyzed Negishi cross-coupling reaction of (hetero)arylchlorides. Synthesis of ladder-type π-conjugated heteroacenes via palladium-catalyzed double N-arylation and intramolecular O-arylation. A palladium-catalyzed regiospecific synthesis of N-aryl benzimidazoles, Versatile ligand used for the Pd-catalyzed C-N coupling reaction of secondary aryl- and alkyl-amines at low temperature with the Pd precatalyst. Ligand used for the Pd-catalyzed Suzuki-Miyaura coupling of aryl chloride and NHC-boranes. Ligand for the palladium-catalyzed trifluoromethylation of hindered aryl chlorides. Ligand used for the palladium-catalyzed coupling of alkyl boronates. Group: Organic phosphine compounds. Alternative Names: AX8074362; MFCD06798294 (95%); X3474RY19E; CTK8B4848; ANW-46517; 2-DICYCLOHEXYLPHOSPHINO-2',6'-DI-I-PROPOXY-1,1'-BIPHENYL; RW2258; dicyclohexyl-[2-(2,6-diisopropoxyphenyl)phenyl]phosphane; AC-28790; Dicyclohexyl(2', 6'-diisopropoxy-[1, 1'-biphenyl]-2-yl)phosphine. CAS No. 787618-22-8. Molecular formula: C30H43O2P. Mole weight: 466.646g/mol. IUPACName: dicyclohexyl-[2-[2,6-di(propan-2-yloxy)phenyl]phenyl]phosphane. Canonical SMILES: CC (C)OC1=C (C (=CC=C1)OC (C)C)C2=CC=CC=C2P (C3CCCCC3)C4CCCCC4. ECNumber: 616-653-5. Catalog: ACM787618228.
2H-2-Ethyl Candesartan
2H-2-Ethyl Candesartan. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1246819-02-2. IUPAC Name: 2-ethoxy-3-[[4-[2- (2-ethyltetrazol-5-yl) phenyl]phenyl]methyl]benzimidazole-4-carboxylic acid. Molecular Formula: C26H24N6O3. Mole Weight: 468.512. Catalog: APS1246819022. SMILES: CCOc1nc2cccc (C (=O)O)c2n1Cc3ccc (cc3)c4ccccc4c5nnn (CC)n5. Format: Neat.
2H-2-Ethyl Candesartan Cilexetil
2H-2-Ethyl Candesartan Cilexetil. Uses: For analytical and research use. Group: Impurity standards. CAS No. 914613-36-8. IUPAC Name: 1-cyclohexyloxycarbonyloxyethyl 2-ethoxy-3-[[4-[2- (2-ethyltetrazol-5-yl) phenyl]phenyl]methyl]benzimidazole-4-carboxylate. Molecular Formula: C35H38N6O6. Mole Weight: 638.71. Catalog: APS914613368. SMILES: CCOc1nc2cccc (C (=O)OC (C)OC (=O)OC3CCCCC3)c2n1Cc4ccc (cc4)c5ccccc5c6nnn (CC)n6. Format: Neat.
2-Mercaptobenzimidazole
An antidegradant, protecting rubber from oxidation. An intermediate in the synthesis of Rabeprazole. Group: Biochemicals. Alternative Names: 1,3-Dihydro-2H-benzimidazole-2-thione; 2-Benzimidazolinethione; 1H-Benzimidazole-2-thiol; 2-Mercapto-1H-benzimidazole; 2-Thiobenzimidazole; Antigene MB; Antioxidant MB; Permanax 21; Sandant MB; Sumilizer MB; Vulkanox; o-Phenylenethiourea. Grades: Highly Purified. CAS No. 583-39-1. Pack Sizes: 10g. US Biological Life Sciences.
Worldwide
2-Nitro-5-phenylthioaniline
2-Nitro-5-phenylthioaniline is a useful synthetic intermediate. It was used to synthesize methyl 5(6)-phenylsulfinyl-2-benzimidazolecarbamate as a potent anthelmintic. Group: Biochemicals. Grades: Highly Purified. CAS No. 43156-47-4. Pack Sizes: 10g, 25g. Molecular Formula: C12H10N2O2S. US Biological Life Sciences.
Worldwide
2-Phenylbenzyl Bromide
2-Phenylbenzyl Bromide is used as a reagnet in synthesizing diarylmethyl benzimidazoles as inhibitors of hepatitis C virus RNA-dependent RNA polymerase. Group: Biochemicals. Grades: Highly Purified. CAS No. 19853-09-9. Pack Sizes: 500mg, 1g. Molecular Formula: C13H11Br, Molecular Weight: 247.13. US Biological Life Sciences.
3-[4-[ (Methylamino) carbonyl]phenyl]-2-propenoic Acid can be used as reactant/reagent in preparation of benzimidazoles and analogs as bradykinin antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 160648-00-0. Pack Sizes: 50mg, 100mg. Molecular Formula: C11H11NO3, Molecular Weight: 205.21. US Biological Life Sciences.
Worldwide
4-Chloro-o-phenylenediamine
4-chloro-o-phenylenediamine appears as brown crystalline solid or powder. (NTP, 1992). Uses: Undergoes cyclizations and cyclocondensations to form benzimidazoles. Group: Monomers. Alternative Names: 4-Chloro-1,2-diaminobenzene. CAS No. 95-83-0. Pack Sizes: Packaging 5, 25 g in glass bottle. Product ID: 4-chlorobenzene-1,2-diamine. Molecular formula: 142.59. Mole weight: ClC6H3(NH2)2. Nc1ccc(Cl)cc1N. 1S/C6H7ClN2/c7-4-1-2-5 (8)6 (9)3-4/h1-3H, 8-9H2. BXIXXXYDDJVHDL-UHFFFAOYSA-N.
Azilsartan medoxomil monopotassium is an azilsartan prodrug and and an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM. It is used in the treatment of adults with essential hypertension. It inhibited cell proliferation at concentrations as low as 1 μmol/l in aortic endothelial cells in vitro. It has antiproliferative effects of azilsartan were also observed in cells lacking AT1 receptors. It was developed by Takeda Corporation. It has been listed. Uses: Azilsartan medoxomil monopotassium is used in the treatment of adults with essential hypertension. Synonyms: 1-[[2'-(2,5-Dihydro-5-oxo-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-yl]methyl]-2-ethoxy-1H-benzimidazole-7-carboxylic acid (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester potassium salt;Azilsartan MedoxoMil PotassiuM salt;Azilsartan kamedoxomil;TAK 491 monopotassium;Potassium,(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 2-ethoxy-3-[[4-[2- (5-oxo-1-oxa-2-aza-4-azanidacyclopent-2-en-3-yl) phenyl]phenyl]methyl]benzimidazole-4-carboxylate. Grades: >98%. CAS No. 863031-24-7. Molecular formula: C30H23KN4O8. Mole weight: 606.63.
BML-277
BML-277 is a selective APT-competitive inhibitor of the DNA damage response signaling enzyme CHK2 ( IC50 =15 nM). Uses: A selective apt-competitive inhibitor. Synonyms: BML-277; BML 277; BML277; Chk2 Inhibitor II;2-[4-(4-chlorophenoxy)phenyl]-3H-benzimidazole-5-carboxamide. Grades: ≥98%. CAS No. 516480-79-8. Molecular formula: C20H14ClN3O2. Mole weight: 363.80.
BMS-212122
BMS-212122 is a benzimidazole-based analogue of the potent MTP inhibitor BMS-201038. Synonyms: 9-[4-[2, 5-dimethyl-4-[[2-[4- (trifluoromethyl) phenyl]benzoyl]amino]benzimidazol-1-yl]butyl]-N- (2, 2, 2-trifluoroethyl) fluorene-9-carboxamide; BMS-212122; BMS212122; BMS 212122; UNII-0Z473OO6GB. Grades: >98%. CAS No. 194213-64-4. Molecular formula: C43H36F6N4O2. Mole weight: 754.76.
Candesartan cilexetil methoxy analogue
Heterocyclic Organic Compound. Alternative Names: 2-Methoxy-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic Acid 1-[[ (Cyclohexyloxy)carbonyl]oxy]ethyl Ester. CAS No. 1026042-12-5. Molecular formula: C32H32N6O6. Mole weight: 596.63. Appearance: Off- White to Pale Yellow solid. Purity: 0.96. IUPACName: 1-cyclohexyloxycarbonyloxyethyl 2-methoxy-3-[[4-[2- (2H-tetrazol-5-yl) phenyl]phenyl]methyl]benzimidazole-4-carboxylate. Canonical SMILES: CC (OC (=O)C1=C2C (=CC=C1)N=C (N2CC3=CC=C (C=C3)C4=CC=CC=C4C5=NNN=N5)OC)OC (=O)OC6CCCCC6. Catalog: ACM1026042125.
Candesartan-d4
Labeled Candesartan, an angiotensin II type-1 receptor antagonist. Used in treatment of congestive heart failure. Antihypertensive. Group: Biochemicals. Alternative Names: 2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1-(phenyl-d4)-1-phenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic Acid; CV-11974-d4; Candesartan M1-d4. Grades: Highly Purified. CAS No. 1346604-70-3. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Candesartan Ethyl Ester
Candesartan Ethyl Ester. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Ethyl 2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylate,Candesartan Cilexetil Imp, A (EP), Candesartan Cilexetil Imp. A (EP), Candesartan Cilexetil USP Related Compound A, Candesartan Cilexetil USP RC A. CAS No. 139481-58-6. IUPAC Name: ethyl 2-ethoxy-3-[[4-[2- (1H-tetrazol-5-yl) phenyl]phenyl]methyl]benzimidazole-4-carboxylate. Molecular Formula: C26H24N6O3. Mole Weight: 468.51. Catalog: APS139481586. SMILES: CCOC (=O)c1cccc2nc (OCC)n (Cc3ccc (cc3)c4ccccc4c5nnn[nH]5)c12. Format: Neat.
Dabigatran
Dabigatran is a very potent anticoagulant, shows that the terminal phenyl can be substituted by the more hydrophilic 2-pyridyl group without substantial loss of activity. Uses: Benzimidazoles; beta-alanine/analogs & derivatives. Synonyms: BIBR 953; BIBR953; BIBR-953. Grades: >98%. CAS No. 211914-51-1. Molecular formula: C25H25N7O3. Mole weight: 471.51.
Dabigatran 3-?Amino-?3-?oxopropyl
Dabigatran 3-Amino-3-oxopropyl is an impurity of Dabigatran. Dabigatran is a very potent anticoagulant, in which the terminal phenyl can be substituted by the more hydrophilic 2-pyridyl group without substantial loss of activity. Synonyms: N-(3-amino-3-oxopropyl)-2-(((4-carbamimidoylphenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamide; 2-[[[4- (Aminoiminomethyl) ?phenyl]?amino]?methyl]?-N- (3-amino-3-oxopropyl) ?-1-methyl-N-2-pyridinyl-1H-benzimidazole-5-carboxamide. CAS No. 1643377-48-3. Molecular formula: C25H26N8O2. Mole weight: 470.53.
Dabigatran Impurity 10 HCl
Dabigatran Impurity 10 HCl is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Synonyms: Ethyl 2-[ ({4-[ethoxy (imino)methyl]phenyl}amino)methyl]-1-methyl-1H-benzimidazole-5-carboxylate hydrochloride (1:1); 2-[[[4- (Ethoxyiminomethyl) phenyl]amino]methyl]-1-methyl-1H-benzimidazole-5-carboxylic Acid Ethyl Ester Hydrochloride. CAS No. 1427571-33-2. Molecular formula: C21H25N4O3Cl. Mole weight: 416.91.
Dabigatran Impurity 28
Dabigatran Impurity 28 is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Synonyms: Ethyl 2-{[ (4-{[ (hexyloxy) carbonyl]carbamoyl}phenyl) amino]methyl}-1-methyl-1H-benzimidazole-5-carboxylate. CAS No. 1807758-61-7. Molecular formula: C26H32N4O5. Mole weight: 480.57.
Dabigatran Impurity 54
Dabigatran Impurity 54 is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Synonyms: 2- [ [ [4- [ (Z) -Amino [ [ (hexyloxy) carbonyl] imino] methyl] phenyl] amino] methyl] -1-methyl-1H-benzimidazole-5-carboxylic Acid. Grades: >90%. CAS No. 1848337-06-3. Molecular formula: C24H29N5O4. Mole weight: 451.53.
Dabigatran Impurity H
Des-(N-2-pyridyl-β-alanine ethyl ester) Dabigatran etexilate 5-ethyl carboxylate is a derivative of Dabigatran, an oral thrombin inhibitor used to prevent venous thromboembolism. Synonyms: Des-(N-2-pyridyl-β-alanine Ethyl Ester) Dabigatran Etexilate 5-Ethyl Carboxylate; 2- [ [ [4- [ [ [ (Hexyloxy) carbonyl] amino] iminomethyl] phenyl] amino] methyl] -1-methyl-1H-benzimidazole-5-carboxylic Acid Ethyl Ester. Grades: > 95%. CAS No. 1408238-36-7. Molecular formula: C26H33N5O4. Mole weight: 479.57.
Deltarasin
Deltarasin inhibits the interaction of RAS with PDEδ with KD of 41 nM. Inhibition of PDEδ-KRAS interaction by Deltarasin suppresses proliferation of human pancreatic ductal adenocarcinoma cells that are dependent on oncogenic KRAS. Synonyms: Deltarasin; 1440898-61-2; CHEMBL3286929; 1-benzyl-2-[4-[(2S)-2-(2-phenylbenzimidazol-1-yl)-2-piperidin-4-ylethoxy]phenyl]benzimidazole; 1440898-82-7; SCHEMBL15474539; BCP20971; EX-A1042; BDBM50019865; MFCD26793865; NSC779408; s7224; AKOS030526539; CCG-270204; CS-1611; NSC-779408; NCGC00378602-10; AC-32917; HY-15747; MS-30649; SW219816-1; J-690178; (S)-1-benzyl-2-(4-(2-(2-phenyl-1H-benzo[d]imidazol-1-yl)-2-(piperidin-4-yl)ethoxy)phenyl)-1H-benzo[d]imidazole; 1-[(1S)-2-[4-(1-benzyl-1H-1,3-benzodiazol-2-yl)phenoxy]-1-(piperidin-4-yl)ethyl]-2-phenyl-1H-1,3-benzodiazole; 1-benzyl-2-{4-[(2S)-2-(2-phenyl-1H-1,3-benzodiazol-1-yl)-2-(piperidin-4-yl)ethoxy]phenyl}-1H-1,3-benzodiazole; O7T. Grades: >98%. CAS No. 1440898-61-2. Molecular formula: C40H37N5O. Mole weight: 603.75.
Enviroxime is a benzimidazole derivative that inhibits the replication of rhinoviruses and poliovirus by targeting protein 3A. Enviroxime exhibits antiviral effects against EV71 with EC50 of 0.15 μM. Uses: Coxsackievirus infections; picornavirus infections. Synonyms: (1E)-[2-Amino-1-[(1-methylethyl)sulfonyl]-1H-benzimidazol-6-yl]phenylmethanone Oxime; 6-[(E)-(Hydroxyimino)phenylmethyl]-1-[(1-methylethyl)sulfonyl]- 1H-Benzimidazol-2-amine; LY 122772; LY122772; LY-122772. Grades: 98%. CAS No. 72301-79-2. Molecular formula: C17H18N4O3S. Mole weight: 358.41.
An impurity of Dabigatran. Dabigatran is a very potent anticoagulant, showing that the terminal phenyl can be substituted by the more hydrophilic 2-pyridyl group without substantial loss of activity. Synonyms: 2-[[[4- (Aminoiminomethyl) phenyl]amino]methyl]-1-methyl-1H-benzimidazole-5-carboxylic Acid Ethyl Ester Hydrochloride; Dabigatran impurity 14. Grades: ≥95%. CAS No. 1422435-39-9. Molecular formula: C19H22ClN5O2. Mole weight: 387.86.
Fenbendazole is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites with an IC50 of about 0.01 μg/ml. Uses: Antinematodal agents. Synonyms: fenbendazole; 43210-67-9; Panacur; Fenbendazol; Phenbendasol; Fenbendazolum; Hoe 881v; Safe-Guard; Methyl 5-(phenylthio)-2-benzimidazolecarbamate; Safe-quard; Panacur aquasol; HOE-881v; 2-(Methoxycarbonylamino)-5-(phenylthio)benzimidazole; Fenbendazole (Panacur); CCRIS 7309; methyl (6-(phenylthio)-1H-benzo[d]imidazol-2-yl)carbamate; Fenbendazol [INN-Spanish]; Fenbendazolum [INN-Latin]; EINECS 256-145-7; methyl [5-(phenylsulfanyl)-1H-benzimidazol-2-yl]carbamate; methyl N-(6-phenylsulfanyl-1H-benzimidazol-2-yl)carbamate; NSC-757824; UNII-621BVT9M36; Fenbendazole for veterinary use; HOE-881Y; DTXSID0040672; methyl N-[5-(phenylsulfanyl)-1H-1,3-benzodiazol-2-yl]carbamate; CHEBI:77092; Carbamic acid, (5-(phenylthio)-1H-benzimidazol-2-yl)-, methyl ester; Methyl (5-(phenylthio)-1H-benzimidazol-2-yl)carbamate; 621BVT9M36; 5-(phenylthio)-2-benzimidazolecarbamic acid methyl ester; Fenbendazole (USP/INN); 2-Benzimidazolecarbamic acid, 5-(phenylthio)-, methyl ester. Grades: >98%. CAS No. 43210-67-9. Molecular formula: C15H13N3O2S. Mole weight: 299.35.
Fenbendazole
United States Pharmacopeia (USP) Reference Standard. Uses: For analytical and research use. Group: Pharmacopeia & metrological institutes standards; pharma & vet compounds & metabolites; standards for environmental regulatory methods; pharma & vet compounds & metabolites; api standards; british pharmacopoeia; european pharmacopoeia (ph. eur.); impurity standards; pharmaceutical toxicology; pharmacopoeial standards. Alternative Names: Fenbendazole, Methyl [5-(phenylsulfanyl)-1H-benzimidazol-2-yl]carbamate, 2-(Methoxycarbonylamino)-5-(phenylthio)benzimidazole, Axilur, Febendazole, Fenbendazol, Fenbendazole, Fenbion, HOE 881, Methyl 5-(phenylthio)-2-benzimidazolecarbamate, Methyl [5-(phenylthio)-1H-benzimidazol-2-yl]carbamate, Panacur, Safe-Guard, Vigisol. CAS No. 43210-67-9. Pack Sizes: 100MG. IUPAC Name: methyl N-(5-phenylsulfanyl-1H-benzimidazol-2-yl)carbamate. Molecular Formula: C15H13N3O2S. Mole Weight: 299.35. Catalog: APS43210679. SMILES: COC(=O)Nc1nc2cc(Sc3ccccc3)ccc2[nH]1. Format: Neat.
Fenbendazole amine hydrochloride
Fenbendazole amine hydrochloride. Uses: For analytical and research use. Group: Pharma & vet compounds & metabolites; pharma & vet compounds & metabolites. Alternative Names: 5-(Phenylthio)-2-aminobenzimidazole hydrochloride, 2-Amino-5-(phenylthio)benzimidazole hydrochloride,1H-Benzimidazol-2-amine, 6-(phenylthio)-, hydrochloride (1:1), 6-(Phenylthio)-1H-benzimidazol-2-amine hydrochloride, 5-Phenylthio-2-aminobenzimidazole hydrochloride, Fenbendazole-amine hydrochloride. CAS No. 1448346-29-9. IUPAC Name: 5-phenylsulfanyl-1H-benzimidazol-2-amine;hydrochloride. Molecular Formula: C13H11N3S.ClH. Mole Weight: 277.77. Catalog: APS1448346299. SMILES: Cl.Nc1nc2cc(Sc3ccccc3)ccc2[nH]1. Format: Neat.
Fenbendazole-[d3]
Fenbendazole-[d3] is the labelled analogue of Fenbendazole. Fenbendazole is an anthelmintic agent that reduces plasma total oxidant status and alters precursor B lymphocytes and splenic cell proliferation. Synonyms: Fenbendazole-D3; (5-Phenylsulfanyl-1H-benzoimidazol-2-yl)-carbamic acid methyl-D3 ester; N-[6-(Phenylthio)-1H-benzimidazol-2-yl]carbamic Acid Methyl-d3 Ester; 2-[(Methoxy-d3)carbonylamino]-5-(phenylthio)benzimidazole; Axilur-d3; Fenbendazol-d3; Fenbion-d3; (Methyl-d3) 5-(Phenylthio)-2-benzimidazolecarbamate; Methyl-d3 [5-(Phenylthio)-1H-benzimidazol-2-yl]carbamate; Panacur-d3. Grades: ≥98%; ≥99% atom D. CAS No. 1228182-47-5. Molecular formula: C15H10D3N3O2S. Mole weight: 302.37.
Flibanserin
Flibanserin, a benzimidazole derivative, has been found to be a Serotonin 1A/2A receptor agonist that was once studied as antidepressant as well as anxiolytic agent and could be used against female sexual dysfunction. Synonyms: EBD6396; EBD 6396; EBD-6396; Flibanserin;Bimt 17;3-[2-[4-[4-(Trifluoromethyl)phenyl]piperazin-1-yl]ethyl]-1H-benzimidazol-2-one. Grades: 98%. CAS No. 167933-07-5. Molecular formula: C20H21F3N4O. Mole weight: 390.40.
GW843682X
GW843682X is a cell-permeable thiophene-benzimidazole compound that acts a selective PLK1 and PLK3 inhibitor with IC50s of 2.2 nM(PLK1) and 9.1 nM(PLK3). Uses: A polo-like kinase-1 (plk1) and polo-like kinase-3 (plk3) inhibitor. Synonyms: GW843682X; GW 843682X; GW-843682X. 5- (5, 6-dimethoxybenzimidazol-1-yl) -3-[[2- (trifluoromethyl) phenyl]methoxy]thiophene-2-carboxamide; Polo-like Kinase Inhibitor III. Grades: ≥98%. CAS No. 660868-91-7. Molecular formula: C22H18F3N3O4S. Mole weight: 477.46.
A cell-permeable phenyl sulfonyl benzimidazole that is shown to dock in the ligand-binding pocket of both HNF4a and HNF4g and antagonize HNF4a DNA binding activity in HepG2 cells (by 93%; 10uM overnight), effectively inhibiting HNF4a-dependent cellular activities (Effective conc. 1 to 5uM). HNF4g inhibition by BI6015 can also lead to decreased insulin promoter binding by transactivators E47 & PDX-1 in T6PNE cells (5uM 48h). Although BI6015 is found to exhibit cancer-selective cytotoxicity toward a panel of 58 human cancer cells and Hep3B-Luc (Effective conc. 1 to 10uM), but not primary murine hepatocytes, it does cause hepatic steatosis both in vitro and in mice in vivo, limiting its use in animal studies. BI6015 also inhibits Human CYP450 2C19 and rat L-type calcium channel (by 94% and 83%, respectively, at 10uM), but not PPARg or a panel of 41 receptors/enzymes of human, mouse, and rat origin. Group: Biochemicals. Grades: Highly Purified. CAS No. 93987-29-2. Pack Sizes: 25mg. Molecular Formula: C??H??N?O?S, Molecular Weight: 331.4. US Biological Life Sciences.
Worldwide
Lansoprazole EP Impurity D
2-Hydroxybenzimidazole is an intermediate of Droperidol and Lansoprazole. Synonyms: 2H-Benzimidazol-2-one, 1,3-dihydro-; 1,3-Dihydro-2H-benzimidazol-2-one; 2-Benzimidazolinone; 1,3-Dihydro-2H-benzimidazole-2-one; 1,3-Dihydro-2H-benzo[d]imidazol-2-one; 1H-1,3-Benzodiazol-2-ol; 1H-Benzimidazol-2(3H)-one; 1H-Benzo[d]imidazol-2(3H)-one; 1H-Benzoimidazol-2-ol; 2(3H)-Benzimidazolone; 2(3H)-Oxobenzimidazole; 2,3-Dihydro-1H-1,3-benzodiazol-2-one; 2,3-Dihydro-2-oxo-1H-benzimidazole; 2-Benzimidazolol; 2-Benzimidazolone; 2-Hydroxybenzimidazole; N,N'-(1,2-Phenyleneurea); NSC 10383; NSC 178108; o-Phenyleneurea; Urea, N,N'-(1,2-phenylene)-. Grades: ≥95%. CAS No. 615-16-7. Molecular formula: C7H6N2O. Mole weight: 134.14.
Mebendazole-amine
2-Amino-5(6)-benzoylbenzimidazole is the minor urinary metabolite of Mebendazole in man. It is a Mebendazole impurity. Synonyms: 2-Amino-5(6)-benzoylbenzimidazole; (2-Amino-1H-benzimidazol-6-yl)phenylmethanone; (2-Amino-1H-benzimidazol- 5-yl)phenylmethanone; G 1029; R 18986; Mebendazole amine. Grades: > 95%. CAS No. 52329-60-9. Molecular formula: C14H11N3O. Mole weight: 237.26.
O-Desethyl Candesartan Cilexetil
O-Desethyl Candesartan Cilexetil. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: O-Desethyl Candesartan Cilexetil, (1RS)-1-[[(Cyclohexyloxy)carbonyl]-oxy]ethyl 2-Oxo-3-[[2'-(1H-tetrazol-5-yl-)-biphenyl-4-yl]methyl]-2,3-dihydro-1H-benzimidazole-4-carboxylate, 1H-Benzimidazole-4-carboxylic acid, 2,3-dihydro-2-oxo-3-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, 1-[[(cyclohexyloxy)carbonyl]oxy]ethyl ester (9CI), 1H-Benzimidazole-4-carboxylic acid, 2,3-dihydro-2-oxo-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, 1-[[(cyclohexyloxy)carbonyl]oxy]ethyl ester, Candesartan Cilexetil Imp. B (EP). CAS No. 869631-11-8. IUPAC Name: 1-cyclohexyloxycarbonyloxyethyl 2-oxo-3-[[4-[2-(1H-tetrazol-5-yl)phenyl]phenyl]methyl]-1H-benzimidazole-4-carboxylate. Molecular Formula: C31H30N6O6. Mole Weight: 582.61. Catalog: APS869631118. SMILES: CC (OC (=O)OC1CCCCC1)OC (=O)c2cccc3NC (=O)N (Cc4ccc (cc4)c5ccccc5c6nnn[nH]6)c23. Format: Neat.