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100g Pack Size. Group: Building Blocks, Research Organics & Inorganics. Formula: C12H10S2. CAS No. 882-33-7. Prepack ID 90029508-100g. Molecular Weight 218.34. See USA prepack pricing.
Phenyldisulfide
An impurity of Nelfinavir, which is a potent and orally bioavailable human immunodeficiency virus HIV-5 protease inhibitor. Synonyms: (phenyldisulfanyl)benzene. Grades: 97 %. CAS No. 882-33-7. Molecular formula: C12H10S2. Mole weight: 218.34.
1,1-Diphenyl-bis-tetrazole-5,5-disulfide
Heterocyclic Organic Compound. Alternative Names: 1,1-Diphenyl-bis-tetrazole-5,5-disulfide;5,5'-Dithio-bis-(1-phenyl-1H-tetrazole);5,5'-Dithio-bis-(1-phenyltetrazole). CAS No. 5117-7-7. Molecular formula: C14H10N8S2. Catalog: ACM1175174.
Heterocyclic Organic Compound. Alternative Names: 3-Tyr-octreotide;[Tyr3]-octreotide, [Tyr3]-SMS 201-995;L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic(2-7) disulfide;[Tyr3]-Octreotide. CAS No. 103667-46-5. Molecular formula: C49H66N10O11S2. Catalog: ACM103667465.
4,4'-Dithiobisphenylacetic acid
4,4'-Dithiobisphenylacetic acid. Group: Biochemicals. Alternative Names: 4,4'-Dithiobisbenzeneacetic acid disulfide; (Dithiodi-p-phenylene)di-acetic acid; NSC 211. Grades: Highly Purified. CAS No. 5325-76-8. Pack Sizes: 1g, 2g, 5g. Molecular Formula: C16H14O4S2. US Biological Life Sciences.
Worldwide
Ac-Asp(5)-AVP
Ac-Asp(5)-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: Ac-Asp(5)-Vasopressin; N-Ac-Asp(5)-AVP; [Cys(Ac)1-Asp(5)]-Argipressin; Ac-Cys-Tyr-Phe-Gln-Asp-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); Acetyl-L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-aspartyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide. CAS No. 2594426-06-7. Molecular formula: C48H66N14O14S2. Mole weight: 1127.26.
Ac-AVP
Ac-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: Vasopressin, N-acetyl-8-L-arginine-; Vasopressin, 1-(N-acetyl-L-cysteine)-8-arginine; Vasopressin, 8-acetylarginine; 1-Acetylcysteine-8-arginine-vasopressin; N-Acetyl-Vasopressin; N-acetyl-L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide; Ac-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); Ac-Vasopressin; N-Acetyl-8-L-argininevasopressin. CAS No. 38106-69-3. Molecular formula: C48H67N15O13S2. Mole weight: 1126.28.
Acetyl-(D-Arg10,Cys11,D-Phe14,Cys17)-β-MSH (10-17) amide, a selective and highly potent β-MSH-derived melanocortin-4 receptor (MC-4R) agonist, has sub-nanomolar potency with the binding affinities of 0.55±0.06, 16.78±1.53, 56.79±4.66 and <500 nM for human MC-4R, MC-1R, MC-3R and MC-5R, respectively. Synonyms: Ac-D-Arg-Cys-Glu-His-D-Phe-Arg-Trp-Cys-NH2 (Disulfide bridge: Cys2-Cys8); N-acetyl-D-arginyl-L-cysteinyl-L-alpha-glutamyl-L-histidyl-D-phenylalanyl-L-arginyl-L-tryptophyl-L-cysteinamide (2->8)-disulfide; 3-[(4R,7S,10S,13R,16S,19S,22R)-22-{[N2-Acetyl-N5-(diaminomethylene)-D-ornithyl]amino}-13-benzyl-4-carbamoyl-10-{3-[(diaminomethylene)amino]propyl}-16-(1H-imidazol-5-ylmethyl)-7-(1H-indol-3-ylmethyl)-6,9,12,15,18,21-hexaoxo-1,2-dithia-5,8,11,14,17,20-hexaazacyclotricosan-19-yl]propanoic acid; L-Cysteinamide, N2-acetyl-D-arginyl-L-cysteinyl-L-α-glutamyl-L-histidyl-D-phenylalanyl-L-arginyl-L-tryptophyl-, cyclic (2?8)-disulfide. Grades: ≥95%. CAS No. 819048-44-7. Molecular formula: C51H70N18O11S2. Mole weight: 1175.36.
Ac-Octreotide
Ac-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: Ac-D-phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); N-Acetyl-Phe-Octreotide; L-Cysteinamide, N-acetyl-D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?7)-disulfide; L-Cysteinamide, N-acetyl-D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?7)-disulfide, [R-(R*,R*)]-; N-Acetyl-D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic (2?7)-disulfide; D-Phe(Ac)-Octreotide; Ac-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol (Disulfide bridge: Cys2-Cys7). Grades: ≥95%. CAS No. 83795-61-3. Molecular formula: C51H68N10O11S2. Mole weight: 1061.28.
Adrenomedullin (1-52), human
Adrenomedullin is an antimicrobial peptide produced by adrenal medulla, skin, Homo sapiens (Human). It has antibacterial activity against Gram-positive and Gram-negative bacteria. In addition to controlling fluid-electrolyte homeostasis, adrenomedullin is an effective vasodilatory peptide hormone and can inhibit ACTH secretion of pituitary gland. Synonyms: H-Tyr-Arg-Gln-Ser-Met-Asn-Asn-Phe-Gln-Gly-Leu-Arg-Ser-Phe-Gly-Cys(1)-Arg-Phe-Gly-Thr-Cys(1)-Thr-Val-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Asn-Val-Ala-Pro-Arg-Ser-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2; L-tyrosyl-L-arginyl-L-glutaminyl-L-seryl-L-methionyl-L-asparagyl-L-asparagyl-L-phenylalanyl-L-glutaminyl-glycyl-L-leucyl-L-arginyl-L-seryl-L-phenylalanyl-glycyl-L-cysteinyl-L-arginyl-L-phenylalanyl-glycyl-L-threonyl-L-cysteinyl-L-threonyl-L-valyl-L-glutaminyl-L-lysyl-L-leucyl-L-alanyl-L-histidyl-L-glutaminyl-L-isoleucyl-L-tyrosyl-L-glutaminyl-L-phenylalanyl-L-threonyl-L-alpha-aspartyl-L-lysyl-L-alpha-aspartyl-L-lysyl-L-alpha-aspartyl-L-asparagyl-L-valyl-L-alanyl-L-prolyl-L-arginyl-L-seryl-L-lysyl-L-isoleucyl-L-seryl-L-prolyl-L-glutaminyl-glycyl-L-tyrosinamide (16->21)-disulfide; Human adrenomedullin; Adrenomedullin (human); Human adrenomedullin-(1-52)-NH2. Grades: >95%. CAS No. 148498-78-6. Molecular formula: C264H406N80O77S3. Mole weight: 6028.82.
Adrenomedullin (16-31), human
Adrenomedullin (16-31), human is the 16-31 fragment of the amino acid residue of human adreomedullin (HADM). Synonyms: H-Cys-Arg-Phe-Gly-Thr-Cys-Thr-Val-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-NH2; L-cysteinyl-L-arginyl-L-phenylalanyl-glycyl-L-threonyl-L-cysteinyl-L-threonyl-L-valyl-L-glutaminyl-L-lysyl-L-leucyl-L-alanyl-L-histidyl-L-glutaminyl-L-isoleucyl-L-tyrosinamide (1->6)-disulfide. Grades: ≥95%. CAS No. 318480-38-5. Molecular formula: C82H129N25O21S2. Mole weight: 1865.19.
AdTx1
AdTx1 is a high affinity, selective and non-competitive α1A adrenoceptor antagonist with Ki value of 0.35 nM. It is a 65 amino-acid peptide originally isolated from the venom of the green mamba. It is stabilized by four disulfide bridges and belongs to the family of the three-finger-fold peptide. It displays no significant activity against a range of other GPCRs. It antagonizes effects of phenylephrine on intra-urethral pressure in rats and on isolated rabbit prostate muscle in vitro. It is used as a potent relaxant of smooth muscles. Synonyms: ρ-Da1a. Grades: >98%. Molecular formula: C310H481N87O100S8. Mole weight: 7283.22.
Agitoxin 2
Agitoxin-2 is a potent and selective blocker of the Shaker type voltage-gated Kv1.3 and Kv1.1 channels. Agitoxin-2 inhibits Kv1.3 with an IC50 value of around 200 pM and Kv1.1 with an IC50 value of around 140 pM. Synonyms: AGTX2; H-Gly-Val-Pro-Ile-Asn-Val-Ser-Cys(1)-Thr-Gly-Ser-Pro-Gln-Cys(2)-Ile-Lys-Pro-Cys(3)-Lys-Asp-Ala-Gly-Met-Arg-Phe-Gly-Lys-Cys(1)-Met-Asn-Arg-Lys-Cys(2)-His-Cys(3)-Thr-Pro-Lys-OH; glycyl-L-valyl-L-prolyl-L-isoleucyl-L-asparagyl-L-valyl-L-seryl-L-cysteinyl-L-threonyl-glycyl-L-seryl-L-prolyl-L-glutaminyl-L-cysteinyl-L-isoleucyl-L-lysyl-L-prolyl-L-cysteinyl-L-lysyl-L-alpha-aspartyl-L-alanyl-glycyl-L-methionyl-L-arginyl-L-phenylalanyl-glycyl-L-lysyl-L-cysteinyl-L-methionyl-L-asparagyl-L-arginyl-L-lysyl-L-cysteinyl-L-histidyl-L-cysteinyl-L-threonyl-L-prolyl-L-lysine (8->28),(14->33),(18->35)-tris(disulfide). Grades: >98%. CAS No. 168147-41-9. Molecular formula: C169H278N54O48S8. Mole weight: 4090.87.
Amylin, amide, rat acetate is a potent and high-affinity ligand for the AMY1 and AMY3 receptors and variably of AMY2 receptors. Synonyms: H-Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-Arg-Ser-Ser-Asn-Asn-Leu-Gly-Pro-Val-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2.CH3CO2H (Disulfide bridge: Cys2-Cys7); L-lysyl-L-cysteinyl-L-asparagyl-L-threonyl-L-alanyl-L-threonyl-L-cysteinyl-L-alanyl-L-threonyl-L-glutaminyl-L-arginyl-L-leucyl-L-alanyl-L-asparagyl-L-phenylalanyl-L-leucyl-L-valyl-L-arginyl-L-seryl-L-seryl-L-asparagyl-L-asparagyl-L-leucyl-glycyl-L-prolyl-L-valyl-L-leucyl-L-prolyl-L-prolyl-L-threonyl-L-asparagyl-L-valyl-glycyl-L-seryl-L-asparagyl-L-threonyl-L-tyrosinamide (2->7)-disulfide acetic acid; Amylin (rat) acetate; Rat amylin acetate; Rat amylin amide acetate; Rat islet amyloid polypeptide acetate. Grades: ≥95%. Molecular formula: C169H276N52O55S2. Mole weight: 3980.45.
Amylin (human)
Amylin, islet Amyloid Polypeptide (IAPP), is a 37-residue peptide hormone secreted by pancreatic β-cells. It inhibits insulin-stimulated glucose uptake, delays gastric emptying and promotes satiety. It has glucose lowering effects in vivo. It is also used to study the mechanisms of amyloid deposition and its role in molecular misfolding processes expecially in conditions such as diabetes type II. Synonyms: L-Tyrosinamide, L-lysyl-L-cysteinyl-L-asparaginyl-L-threonyl-L-alanyl-L-threonyl-L-cysteinyl-L-alanyl-L-threonyl-L-glutaminyl-L-arginyl-L-leucyl-L-alanyl-L-asparaginyl-L-phenylalanyl-L-leucyl-L-valyl-L-histidyl-L-seryl-L-seryl-L-asparaginyl-L-asparaginyl-L-phenylalanylglycyl-L-alanyl-L-isoleucyl-L-leucyl-L-seryl-L-seryl-L-threonyl-L-asparaginyl-L-valylglycyl-L-seryl-L-asparaginyl-L-threonyl-, cyclic (2?7)-disulfide; AC 001; Amlintide; Amylin (human clone WO2013/156594-SEQID-1); Diabetes-associated peptide (human); Human amylin; Human IAPP; Human islet amyloid peptide; Human islet amyloid polypeptide; Human islet amyloid polypeptide-NH2; Islet amyloid polypeptide (human); H-Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2 (Disulfide bridge: Cys2-Cys7). Grades: 95%. CAS No. 122384-88-7. Molecular formula: C165H261N51O55S2. Mole weight: 3903.33.
Amylin (rat)
Amylin (rat), islet Amyloid Polypeptide (IAPP), is a glucoregulatory peptide from rat pancreatic cells. It inhibits glucagon secretion, delays gastric emptying and acts as a satiety agent. It is used to study the regulation of satiety and obesity. It binds to heteromeric complexes of human calcitonin receptor 2 (CTR2) with receptor activity-modifying protein (RAMP) 1 or 3. It also binds to mouse α-thyroid-stimulating hormone thyrotroph (α-TSH) cells and rat nucleus accumbens membrane preparations. It inhibits insulin-induced, but not basal, glycogen synthesis in hepatocytes isolated from fasted rats in vitro. It does not form fibrils and is not cytotoxic unlike human amylin. It is active in vivo. Synonyms: Amylin, amide, rat; Amylin (mouse, rat); IAPP (mouse, rat); Islet amyloid polypeptide (mouse, rat); H-Lys-Cys(1)-Asn-Thr-Ala-Thr-Cys(1)-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-Arg-Ser-Ser-Asn-Asn-Leu-Gly-Pro-Val-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2; L-lysyl-L-cysteinyl-L-asparagyl-L-threonyl-L-alanyl-L-threonyl-L-cysteinyl-L-alanyl-L-threonyl-L-glutaminyl-L-arginyl-L-leucyl-L-alanyl-L-asparagyl-L-phenylalanyl-L-leucyl-L-valyl-L-arginyl-L-seryl-L-seryl-L-asparagyl-L-asparagyl-L-leucyl-glycyl-L-prolyl-L-valyl-L-leucyl-L-prolyl-L-prolyl-L-threonyl-L-asparagyl-L-valyl-glycyl-L-seryl-L-asparagyl-L-threonyl-L-tyrosinamide (2->7)-disulfide. Grades: ≥98%. CAS No. 124447-81-0. Molecular formula: C167H272N52O53S2. Mole weight: 3920.43.
Antiparallel Dimer-AVP
Antiparallel Dimer-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: Anti-Parallel Dimer-Vasopressin; H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2.H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6', Cys1'-Cys6); 2[L-cystyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparginyl-L-cystyl-L-prolyl-L-arginyl-glycinamide] (inter-disulfide bridges between 1,6' and 1',6 cysteines). Molecular formula: C92H130N30O24S4. Mole weight: 2168.48.
AOD9604
AOD 9604 is a modified fragment of human growth hormone (hGH) that is originally developed as an anti-obesity drug. AOD 9604 is formulated as the injection for weight loss, muscle building and so on. Synonyms: L-tyrosyl-L-leucyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-cysteinyl-L-arginyl-L-seryl-L-valyl-L-alpha-glutamyl-glycyl-L-seryl-L-cysteinyl-glycyl-L-phenylalanine (7->14)-disulfide; AOD 9604; LAT 8881; L-Phenylalanine, L-tyrosyl-L-leucyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-cysteinyl-L-arginyl-L-seryl-L-valyl-L-α-glutamylglycyl-L-seryl-L-cysteinylglycyl-, cyclic (7?14)-disulfide. CAS No. 221231-10-3. Molecular formula: C78H123N23O23S2. Mole weight: 1815.08.
AOD9604 acetate
AOD9604 acetate is a modified fragment of human growth hormone (hGH) that was originally developed as an anti-obesity drug. AOD9604 is formulated as the injection for weight loss, muscle building and so on. Synonyms: AOD-9604 acetate; AOD 9604 acetate; H-Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe-OH.CH3CO2H (Disulfide bridge: Cys7-Cys14); L-tyrosyl-L-leucyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-cysteinyl-L-arginyl-L-seryl-L-valyl-L-alpha-glutamyl-glycyl-L-seryl-L-cysteinyl-glycyl-L-phenylalanine (7->14)-disulfide acetic acid; LAT 8881 acetate. Grades: ≥95%. Molecular formula: C80H127N23O25S2. Mole weight: 1875.15.
(Arg8,des-Gly-NH29)-Vasopressin
(Arg8,des-Gly-NH29)-Vasopressin is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: Des-Gly-OH-Vasopressin; H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-OH (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginine (1->6)-disulfide; Des-Gly-OH-AVP; 9-Deglycinamide-argipressin; 9-des-GlyNH2-argipressin; 1-8-Vasopressin, 8-L-arginine-; 8-L-Arginine-1-8-vasopressin; Vasopressin, 8-L-arginine-9-deglycinamide-; 8-Arginine-9-deglycinamide-vasopressin; 8-Arginine-9-desglycinamide vasopressin; [Arg8,de-Gly9]-vasopressin; Org 5667; [Deglycinamide9,arginine8]-vasopressin; [Desglycinamide9-arginine8]-vasopressin; Arginine vasopressin-(1-8). Grades: ≥95% by HPLC. CAS No. 37552-33-3. Molecular formula: C44H61N13O12S2. Mole weight: 1028.17.
(Arg8)-Vasopressin (free acid)
Gly-OH-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: Gly 9-Vasopressin; Arg-Vasopressin-Acid; Gly-OH Vasopressin; L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycine (1->6)-disulfide; Gly-OH Argipressin; Vasopressin, 8-L-arginine-9-glycine-; 8-L-Arginine-9-glycinevasopressin; (Arg8)-Vasopressinoic acid; [Arg8,Gly-OH9]vasopressin; Vasopressinoic acid; H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-OH (Disulfide bridge: Cys1-Cys6); Gly-OH-AVP. Grades: ≥95%. CAS No. 25255-33-8. Molecular formula: C46H64N14O13S2. Mole weight: 1085.23.
Asn(Acm)-Desmopressin
Asn(Acm)-Desmopressin is an impurity of Desmopressin, which is a synthetic octapeptide and an analog of the human hormone arginine vasopressin with antidiuretic and coagulant activities. Synonyms: deamino-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl(Acm)-L-cysteinyl-L-prolyl-D-arginyl-glycinamide (1->6)-disulfide; deamino-Cys-Tyr-Phe-Gln-Asn(Acm)-Cys-Pro-D-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); Mpr-Tyr-Phe-Gln-Asn(Acm)-Cys-Pro-D-Arg-Gly-NH2 (Disulfide Bridge Mpr1-Cys6). Molecular formula: C49H69N15O13S2. Mole weight: 1140.30.
Asp(5)-AVP
Asp(5)-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: Asp5-AVP; Asp(5)-Arg-Vasopressin; Asp(5)-Vasopressin; Vasopressin, 5-L-aspartic acid-8-L-arginine-; H-Cys-Tyr-Phe-Gln-Asp-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-aspartyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide. CAS No. 78031-79-5. Molecular formula: C46H64N14O13S2. Mole weight: 1085.22.
It is a 28-amino acid hormone that inhibits the secretion of endothelin-1 in a dose-dependent manner. Normally, it is produced and secreted by the human heart in response to cardiac injury and mechanical stretching. Synonyms: Atrial Natriuretic Factor (1-28) (human) acetate salt; H-Ser-Leu-Arg-Arg-Ser-Ser-Cys(1)-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys(1)-Asn-Ser-Phe-Arg-Tyr-OH.CH3CO2H; L-seryl-L-leucyl-L-arginyl-L-arginyl-L-seryl-L-seryl-L-cysteinyl-L-phenylalanyl-glycyl-glycyl-L-arginyl-L-methionyl-L-alpha-aspartyl-L-arginyl-L-isoleucyl-glycyl-L-alanyl-L-glutaminyl-L-seryl-glycyl-L-leucyl-glycyl-L-cysteinyl-L-asparagyl-L-seryl-L-phenylalanyl-L-arginyl-L-tyrosine (7->23)-disulfide acetic acid. Grades: ≥95%. CAS No. 1366000-58-9. Molecular formula: C127H203N45O39S3.C2H4O2. Mole weight: 3140.50.
Atrial Natriuretic Peptide (ANP) (1-28), rat TFA
Atrial Natriuretic Peptide (ANP) (1-28), rat TFA is a 28 amino acid peptide corresponding to the rat protein sequence. It is an endogenous peptide synthesized in myoendocrine cells of the heart from which it is released into the circulation. It has effects on the renal and cardiovascular systems that decrease vasoconstriction, increase sodium excretion and inhibit renin secretion. Synonyms: Atrial natriuretic factor (1-28) (rat) (TFA); H-Ser-Leu-Arg-Arg-Ser-Ser-Cys(1)-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys(1)-Asn-Ser-Phe-Arg-Tyr-OH.TFA; L-seryl-L-leucyl-L-arginyl-L-arginyl-L-seryl-L-seryl-L-cysteinyl-L-phenylalanyl-glycyl-glycyl-L-arginyl-L-isoleucyl-L-alpha-aspartyl-L-arginyl-L-isoleucyl-glycyl-L-alanyl-L-glutaminyl-L-seryl-glycyl-L-leucyl-glycyl-L-cysteinyl-L-asparagyl-L-seryl-L-phenylalanyl-L-arginyl-L-tyrosine (7->23)-disulfide trifluoroacetic acid. Grades: >98%. Molecular formula: C128H205N45O39S2.C2HF3O2. Mole weight: 3176.43.
β-Asp(5)-AVP
β-Asp(5)-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: β-Asp(5)-Vasopressin; H-Cys-Tyr-Phe-Gln-β-Asp-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-β-aspartyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide. Molecular formula: C46H64N14O13S2. Mole weight: 1085.22.
β-CGRP, human
β-CGRP, human is a highly effective vasodilator. Synonyms: H-Ala-Cys-Asn-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Met-Val-Lys-Ser-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2 (Disulfide bridge: Cys2-Cys7); Human β-CGRP; CGRP-II (Human); Calcitonin Gene Related Peptide II, human; α-Calcitonin gene-related peptide (human), 3-L-asparagine-22-L-methionine-25-L-serine-; β-Calcitonin gene-related peptide (human); L-Alanyl-L-cysteinyl-L-asparaginyl-L-threonyl-L-alanyl-L-threonyl-L-cysteinyl-L-valyl-L-threonyl-L-histidyl-L-arginyl-L-leucyl-L-alanylglycyl-L-leucyl-L-leucyl-L-seryl-L-arginyl-L-serylglycylglycyl-L-methionyl-L-valyl-L-lysyl-L-seryl-L-asparaginyl-L-phenylalanyl-L-valyl-L-prolyl-L-threonyl-L-asparaginyl-L-valylglycyl-L-seryl-L-lysyl-L-alanyl-L-phenylalaninamide cyclic (2?7)-disulfide; Human beta calcitonin gene-related peptide; Human calcitonin gene-related peptide 2; Human calcitonin gene-related peptide β; Human calcitonin gene-related peptide-II; Human calcitonin-related peptide II; Human β-calcitonin gene-related peptide. Grades: 95%. CAS No. 101462-82-2. Molecular formula: C162H267N51O48S3. Mole weight: 3793.35.
β-CGRP, human acetate
β-CGRP, human acetate, is a calcitonin peptide that acts through a complex of receptor-activity-modifying protein (RAMP) and calcitonin receptor-like receptor (CRLR) with IC50s of 1 and 300 nM for CRLR/RAMP1 and CRLR/RAMP2 in cells, respectively. Synonyms: H-Ala-Cys-Asn-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Met-Val-Lys-Ser-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2.CH3CO2H (Disulfide bridge: Cys2-Cys7); L-alanyl-L-cysteinyl-L-asparagyl-L-threonyl-L-alanyl-L-threonyl-L-cysteinyl-L-valyl-L-threonyl-L-histidyl-L-arginyl-L-leucyl-L-alanyl-glycyl-L-leucyl-L-leucyl-L-seryl-L-arginyl-L-seryl-glycyl-glycyl-L-methionyl-L-valyl-L-lysyl-L-seryl-L-asparagyl-L-phenylalanyl-L-valyl-L-prolyl-L-threonyl-L-asparagyl-L-valyl-glycyl-L-seryl-L-lysyl-L-alanyl-L-phenylalaninamide (2->7)-disulfide acetate. Grades: ≥95%. Molecular formula: C164H271N51O50S3. Mole weight: 3853.46.
Biotinyl-(Arg8)-Vasopressin
Biotinyl-(Arg8)-Vasopressin is an ingeniously engineered peptide hormone exhibiting unparalleled selectivity as an agonist for vasopressin receptors, particularly targeting the esteemed V1A and V1B subtypes. Synonyms: Biotinyl-AVP; Biotinyl-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); N-biotinyl-L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide. Grades: 95%. CAS No. 126703-17-1. Molecular formula: C56H79N17O14S3. Mole weight: 1310.53.
An agonist at atrial natriuretic peptide (ANP) receptor A (NRP1) which is secreted from cardiac ventricles in response to volume increase and pressure overload. It exhibits natriuretic, vasodilatory and lusitropic activity and suppresses sympathetic and renin-angiotensin-aldosterone systems in vivo, and decreases de novo collagen synthesis as well as increases MMP gene expression in vitro. Synonyms: Brain Natriuretic Peptide-32 human; BNP-32 (human); Nesiritide; H-Ser-Pro-Lys-Met-Val-Gln-Gly-Ser-Gly-Cys(1)-Phe-Gly-Arg-Lys-Met-Asp-Arg-Ile-Ser-Ser-Ser-Ser-Gly-Leu-Gly-Cys(1)-Lys-Val-Leu-Arg-Arg-His-OH; L-seryl-L-prolyl-L-lysyl-L-methionyl-L-valyl-L-glutaminyl-glycyl-L-seryl-glycyl-L-cysteinyl-L-phenylalanyl-glycyl-L-arginyl-L-lysyl-L-methionyl-L-alpha-aspartyl-L-arginyl-L-isoleucyl-L-seryl-L-seryl-L-seryl-L-seryl-glycyl-L-leucyl-glycyl-L-cysteinyl-L-lysyl-L-valyl-L-leucyl-L-arginyl-L-arginyl-L-histidine (10->26)-disulfide. Grades: ≥99% by HPLC. CAS No. 124584-08-3. Molecular formula: C143H244N50O42S4. Mole weight: 3464.04.
Brain Natriuretic Peptide (BNP) (1-32), rat
Brain Natriuretic Peptide (BNP) (1-32), rat is a 32-amino acid polypeptide secreted by the ventricle in response to overstretching of cardiomyocytes. Synonyms: Brain Natriuretic Peptide-32 (rat); BNP (1-32), rat; H-Asn-Ser-Lys-Met-Ala-His-Ser-Ser-Ser-Cys(1)-Phe-Gly-Gln-Lys-Ile-Asp-Arg-Ile-Gly-Ala-Val-Ser-Arg-Leu-Gly-Cys(1)-Asp-Gly-Leu-Arg-Leu-Phe-OH; L-asparagyl-L-seryl-L-lysyl-L-methionyl-L-alanyl-L-histidyl-L-seryl-L-seryl-L-seryl-L-cysteinyl-L-phenylalanyl-glycyl-L-glutaminyl-L-lysyl-L-isoleucyl-L-alpha-aspartyl-L-arginyl-L-isoleucyl-glycyl-L-alanyl-L-valyl-L-seryl-L-arginyl-L-leucyl-glycyl-L-cysteinyl-L-alpha-aspartyl-glycyl-L-leucyl-L-arginyl-L-leucyl-L-phenylalanine (10->26)-disulfide. Grades: 95%. CAS No. 133448-20-1. Molecular formula: C146H239N47O44S3. Mole weight: 3452.94.
Calcitonin (rat)
Calcitonin, a peptide hormone involved in calcium and bone metabolism, is effective in treating hypercalcemia caused by bone metastasis, multiple myeloma and osteitis malformation, and is also effective against osteoporosis. Synonyms: H-Cys-Gly-Asn-Leu-Ser-Thr-Cys-Met-Leu-Gly-Thr-Tyr-Thr-Gln-Asp-Leu-Asn-Lys-Phe-His-Thr-Phe-Pro-Gln-Thr-Ser-Ile-Gly-Val-Gly-Ala-Pro-NH2 (Disulfide bridge: Cys1-Cys7); L-cysteinyl-glycyl-L-asparagyl-L-leucyl-L-seryl-L-threonyl-L-cysteinyl-L-methionyl-L-leucyl-glycyl-L-threonyl-L-tyrosyl-L-threonyl-L-glutaminyl-L-alpha-aspartyl-L-leucyl-L-asparagyl-L-lysyl-L-phenylalanyl-L-histidyl-L-threonyl-L-phenylalanyl-L-prolyl-L-glutaminyl-L-threonyl-L-seryl-L-isoleucyl-glycyl-L-valyl-glycyl-L-alanyl-L-prolinamide (1->7)-disulfide. Grades: ≥95%. CAS No. 11118-25-5. Molecular formula: C148H228N40O46S3. Mole weight: 3399.83.
CART (55-102) (human)
Cocaine- and amphetamine-regulated transcript (CART) is a neuropeptide protein with potent appetite-suppressing activity. It inhibits normal and starvation-induced feeding and blocks the neuropeptide Y-induced feeding response. Synonyms: H-Val-Pro-Ile-Tyr-Glu-Lys-Lys-Tyr-Gly-Gln-Val-Pro-Met-Cys-Asp-Ala-Gly-Glu-Gln-Cys-Ala-Val-Arg-Lys-Gly-Ala-Arg-Ile-Gly-Lys-Leu-Cys-Asp-Cys-Pro-Arg-Gly-Thr-Ser-Cys-Asn-Ser-Phe-Leu-Leu-Lys-Cys-Leu-OH (Disulfide bridge: Cys14-Cys32, Cys20-Cys40, Cys34-Cys47); L-valyl-L-prolyl-L-isoleucyl-L-tyrosyl-L-alpha-glutamyl-L-lysyl-L-lysyl-L-tyrosyl-glycyl-L-glutaminyl-L-valyl-L-prolyl-L-methionyl-L-cysteinyl-L-alpha-aspartyl-L-alanyl-glycyl-L-alpha-glutamyl-L-glutaminyl-L-cysteinyl-L-alanyl-L-valyl-L-arginyl-L-lysyl-glycyl-L-alanyl-L-arginyl-L-isoleucyl-glycyl-L-lysyl-L-leucyl-L-cysteinyl-L-alpha-aspartyl-L-cysteinyl-L-prolyl-L-arginyl-glycyl-L-threonyl-L-seryl-L-cysteinyl-L-asparagyl-L-seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-lysyl-L-cysteinyl-L-leucine (14->32),(20->40),(34->47)-tris(disulfide). Grades: ≥95%. CAS No. 214050-22-3. Molecular formula: C225H365N65O65S7. Mole weight: 5245.18.
CART (55-102) (rat)
Cocaine- and amphetamine-regulated transcript (CART) is a neuropeptide protein with potent appetite-suppressing activity. It inhibits normal and starvation-induced feeding and blocks the neuropeptide Y-induced feeding response. Uses: Appetite suppressant. Synonyms: H-Ile-Pro-Ile-Tyr-Glu-Lys-Lys-Tyr-Gly-Gln-Val-Pro-Met-Cys-Asp-Ala-Gly-Glu-Gln-Cys-Ala-Val-Arg-Lys-Gly-Ala-Arg-Ile-Gly-Lys-Leu-Cys-Asp-Cys-Pro-Arg-Gly-Thr-Ser-Cys-Asn-Ser-Phe-Leu-Leu-Lys-Cys-Leu-OH (Disulfide bridge: Cys14-Cys32, Cys20-Cys40, Cys34-Cys37); L-isoleucyl-L-prolyl-L-isoleucyl-L-tyrosyl-L-alpha-glutamyl-L-lysyl-L-lysyl-L-tyrosyl-glycyl-L-glutaminyl-L-valyl-L-prolyl-L-methionyl-L-cysteinyl-L-alpha-aspartyl-L-alanyl-glycyl-L-alpha-glutamyl-L-glutaminyl-L-cysteinyl-L-alanyl-L-valyl-L-arginyl-L-lysyl-glycyl-L-alanyl-L-arginyl-L-isoleucyl-glycyl-L-lysyl-L-leucyl-L-cysteinyl-L-alpha-aspartyl-L-cysteinyl-L-prolyl-L-arginyl-glycyl-L-threonyl-L-seryl-L-cysteinyl-L-asparagyl-L-seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-lysyl-L-cysteinyl-L-leucine (14->32),(20->40),(34->47)-tris(disulfide). Grades: ≥95%. CAS No. 209615-79-2. Molecular formula: C226H367N65O65S7. Mole weight: 5259.21.
Conopressin G
Conopressin G is a vasotocin-like peptide isolated from the venom of the worm-hunting snail (conus imperialis). Synonyms: Glycinamide, L-cysteinyl-L-phenylalanyl-L-isoleucyl-L-arginyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-lysyl-, cyclic (1?6)-disulfide; Conopressin G (Conus geographus); Conopressin L1; Lysine-conopressin (Erpobdella octoculata); Lysine-conopressin (Lymnaea stagnalis); H-Cys-Phe-Ile-Arg-Asn-Cys-Pro-Lys-Gly-NH2 (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-phenylalanyl-L-isoleucyl-L-arginyl-L-asparagyl-L-cysteinyl-L-prolyl-L-lysyl-glycinamide (1->6)-disulfide; Lys-Conopressin-G. Grades: 95%. CAS No. 111317-91-0. Molecular formula: C44H71N15O10S2. Mole weight: 1034.26.
Cortistatin 14, human, rat
Cortistatin 14 is an endogenous neuropeptide similar to somatostatin-14 in structure and function. It is mainly expressed in the cortex and hippocampus. It shows potency at all somatostatin receptors, but prevents somatostatin-14 binding. It binds to the growth hormone secretagog receptor (GHS-R1a). It displays sleep-modulating and neuronal depressant properties in vivo. Synonyms: CST-14, human, rat; Pro-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Ser-Ser-Cys-Lys (Disulfide bridge: Cys2-Cys13); Corticostatin-14; L-prolyl-L-cysteinyl-L-lysyl-L-asparagyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-seryl-L-seryl-L-cysteinyl-L-lysine (2->13)-disulfide; N2-{[(4R, 7S, 10S, 13S, 16S, 19S, 22S, 25S, 28S, 31S, 34S, 37R)-19, 34-Bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13, 25, 28-tribenzyl-16-(1-hydroxyethyl)-7, 10-bis(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6, 9, 12, 15, 18, 21, 24, 27, 30, 33, 36-undecaoxo-37-(L-prolylamino)-1, 2-dithia-5, 8, 11, 14, 17, 20, 23, 26, 29, 32, 35-undecaazacyclooctatriacontan-4-yl]carbonyl}-L-lysine. Grades: ≥95%. CAS No. 193829-96-8. Molecular formula: C81H113N19O19S2. Mole weight: 1721.01.
Cortistatin-17 (human)
Cortistatin-17, a structural analogue of somatostatin, binds to all somatostatin receptor subtypes (SSTR) in a manner similar to rat cortistatin. Its inhibition on the cAMP production of forskolin-stimulated in chinese hamster ovary cells expressing SSTR2-5 are dose-dependent, but slightly less efficient than somatostatin-14. Like rat cortistatin, it affects sleep and wake patterns in rats. It reduces light slow wave sleep (SWS1) and increases deep slow wave sleep (SWS2) in a dose-dependent manner. Administration of the peptide causes a temporary flattening of cortical and hippocampal electroencephalograms. Synonyms: H-Asp-Arg-Met-Pro-Cys-Arg-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Ser-Ser-Cys-Lys-OH (Disulfide bridge: Cys5-Cys16); L-alpha-aspartyl-L-arginyl-L-methionyl-L-prolyl-D-cysteinyl-D-arginyl-L-asparagyl-L-phenylalanyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-D-phenylalanyl-D-seryl-L-seryl-L-cysteinyl-L-lysine (5->16)-disulfide; L-α-Aspartyl-L-arginyl-L-methionyl-N-[(4R, 7S, 10R, 13R, 16S, 19S, 22R, 25S, 28S, 31S, 34R, 37S)-19-(4-aminobutyl)-4-{[(1S)-5-amino-1-carboxypentyl]carbamoyl}-31-(2-amino-2-oxoethyl)-13, 25, 28-tribenzyl-34-(3-carbamimidamidopropyl)-16-[(1R)-1-hydroxyethyl]-7, 10-bis(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6, 9, 12, 15, 18, 21, 24, 27, 30, 33, 36-undecaoxo-1, 2-dithia-5, 8, 11, 14, 17, 20, 23, 26, 29, 32, 35-undecaazacyclooctatriacontan-37-yl]-L-prolinamide. Grades: 95%. CAS No. 189450-19-9. Molecular formula: C96H139N27O24S3. Mole weight: 2151.53.
Cortistatin-29 (human)
Cortistatin-29 (human), an anti-inflammatory and immunomodulatory factor, has potential multistep therapeutic effects in the treatment of septic shock and Crohn's disease. Synonyms: Pyr-Glu-Gly-Ala-Pro-Pro-Gln-Gln-Ser-Ala-Arg-Arg-Asp-Arg-Met-Pro-Cys-Arg-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Ser-Ser-Cys-Lys-OH (Disulfide bridge: Cys17-Cys28); L-Lysine, 5-oxo-L-prolyl-L-α-glutamylglycyl-L-alanyl-L-prolyl-L-prolyl-L-glutaminyl-L-glutaminyl-L-seryl-L-alanyl-L-arginyl-L-arginyl-L-α-aspartyl-L-arginyl-L-methionyl-L-prolyl-L-cysteinyl-L-arginyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-seryl-L-seryl-L-cysteinyl-, cyclic (17?28)-disulfide; CST (human). Grades: ≥95%. CAS No. 1815618-16-6. Molecular formula: C149H223N47O42S3. Mole weight: 3440.86.
Cortistatin-29 (rat)
Cortistatin-29 is a neuropeptide that has structurally similarity to somatostatin-28. It is produced by cleavage of preprocortistatin to procortistatin, which is cleaved at dibasic amino acids to form cortistatin-29 and cortistatin-14 as well as other partial cleavage products. Synonyms: Pyr-Glu-Arg-Pro-Pro-Leu-Gln-Gln-Pro-Pro-His-Arg-Asp-Lys-Lys-Pro-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Ser-Ser-Cys-Lys-OH (Disulfide bridge: Cys17-Cys28); 5-oxo-L-prolyl-L-α-glutamyl-L-arginyl-L-prolyl-L-prolyl-L-leucyl-L-glutaminyl-L-glutaminyl-L-prolyl-L-prolyl-L-histidyl-L-arginyl-L-α-aspartyl-L-lysyl-L-lysyl-L-prolyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-seryl-L-seryl-L-cysteinyl-L-lysine, cyclic (17?28)-disulfide; L-pyroglutamyl-L-alpha-glutamyl-L-arginyl-L-prolyl-L-prolyl-L-leucyl-L-glutaminyl-L-glutaminyl-L-prolyl-L-prolyl-L-histidyl-L-arginyl-L-alpha-aspartyl-L-lysyl-L-lysyl-L-prolyl-D-cysteinyl-D-lysyl-L-asparagyl-L-phenylalanyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-D-phenylalanyl-D-seryl-L-seryl-L-cysteinyl-L-lysine (17->28)-disulfide. Grades: ≥95%. CAS No. 1815618-17-7. Molecular formula: C161H240N46O41S2. Mole weight: 3540.05.
CTAP
CTAP has been found to be a selective μ-opioid receptor antagonist. Synonyms: D-Phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-arginyl-L-threonyl-3-mercapto-L-valyl-L-threoninamide cyclic (2?7)-disulfide. Grades: ≥95% by HPLC. CAS No. 103429-32-9. Molecular formula: C51H69N13O11S2. Mole weight: 1104.32.
CTOP
CTOP has been found to be an effective and selective μ opioid receptor antagonist and could be used in the treatment of pain. Synonyms: D-Phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-ornithyl-L-threonyl-3-mercapto-L-valyl-L-threoninamide Cyclic (2?7)?-Disulfide. Grades: 98%. CAS No. 103429-31-8. Molecular formula: C50H67N11O11S2. Mole weight: 1062.28.
CTOP trifluoroacetate salt
CTOP is a peptide that acts as a selective antagonist of the μ-opioid receptor (IC50 = 2.8 nM). CTOP inhibits the antinociceptive effect of morphine in the tail flick test in mice (ED50 = 0.018 nmol) and reverses morphine-induced increases in locomotor activity (ED50 = 0.02 nmol). Synonyms: Phe-Cys-Tyr-Trp-Orn-Thr-Pen-Thr; D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-ornithyl-L-threonyl-3-mercapto-L-valyl-L-threoninamide-cyclic (2?7)-disulfide trifluoroacetate salt. Grades: ≥98%. Molecular formula: C50H67N11O11S2·xCF3COOH. Mole weight: 1062.3 (free base).
CTTHWGFTLC, CYCLIC acetate
CTTHWGFTLC, CYCLIC acetate is a cyclic peptide inhibitor for matrix metalloproteinases (MMP-2) and MMP-9. Synonyms: L-Cysteine, L-cysteinyl-L-threonyl-L-threonyl-L-histidyl-L-tryptophylglycyl-L-phenylalanyl-L-threonyl-L-leucyl-, cyclic (1?10)-disulfide acetate; CTT 1 acetate; H-Cys-Thr-Thr-His-Trp-Gly-Phe-Thr-Leu-Cys-OH.CH3CO2H (Disulfide Bridge: Cys1-Cys10); L-cysteinyl-L-threonyl-L-threonyl-L-histidyl-L-tryptophyl-glycyl-L-phenylalanyl-L-threonyl-L-leucyl-L-cysteine (1->10)-disulfide acetic acid acetate. Grades: ≥95%. Molecular formula: C54H75N13O16S2. Mole weight: 1226.39.
C-Type Natriuretic Peptide-22 (human, porcine, rat) trifluoroacetate salt
C-Type natriuretic peptide-22 is an endogenous peptide which has diverse biological activities. CNP-22 acts as a selective agonist of natriuretic peptide receptors (NPRs) 2 and 3 (Kds = 7, 10.8, and >500,000 pM for NPR2, 3, and 1, respectively). The 22 amino acid sequence corresponds to residues 105-126 of its precursors prepro CNP, pro CNP, and CNP-53. Synonyms: CNP-22; glycyl-L-leucyl-L-seryl-L-lysylglycyl-L-cysteinyl-L-phenylalanylglycyl-L-leucyl-L-lysyl-L-leucyl-L-α-aspartyl-L-arginyl-L-isoleucylglycyl-L-seryl-L-methionyl-L-serylglycyl-L-leucylglycyl-L-cysteine cyclic (6?22)-disulfide trifluoroacetate salt. Grades: ≥95%. Molecular formula: C93H157N27O28S3·xCF3COOH. Mole weight: 2197.60.
C-Type Natriuretic Peptide (CNP) (1-22), human
C-type natriuretic peptide is an endogenous peptide found in plasma and cerebrospinal fluid. It is composed of 22 amino acids. C-type natriuretic peptide acts as an agonist of natriuretic peptide receptor NPR2 (NPRB) and exhibits affinity for NPR3 (NPRC). It inhibits L-type calcium currents in myocytes and exhibits antiproliferative effects in cardiac fibroblasts in vitro. Regulates cartilage homeostasis, body fluid volume and exhibits vasodilatory activity in vivo. Synonyms: H-Gly-Leu-Ser-Lys-Gly-Cys(1)-Phe-Gly-Leu-Lys-Leu-Asp-Arg-Ile-Gly-Ser-Met-Ser-Gly-Leu-Gly-Cys(1)-OH; glycyl-L-leucyl-L-seryl-L-lysyl-glycyl-L-cysteinyl-L-phenylalanyl-glycyl-L-leucyl-L-lysyl-L-leucyl-L-alpha-aspartyl-L-arginyl-L-isoleucyl-glycyl-L-seryl-L-methionyl-L-seryl-glycyl-L-leucyl-glycyl-L-cysteine (6->22)-disulfide; Natriuretic peptide, C-type; C-type natriuretic peptide (1-22) (human, rat, swine); Atriopeptin C (pig); C-Type Natriuretic Peptide (32-53) (human, porcine, rat). Grades: ≥95%. CAS No. 127869-51-6. Molecular formula: C93H157N27O28S3. Mole weight: 2197.60.
Cyclic somatostatin diacetate
Cyclic somatostatin diacetate is a growth hormone-release inhibiting factor used in the treatment of severe, acute hemorrhages of gastroduodenal ulcers. It's an experimental diabetes drug. Synonyms: Somatostatin (sheep), diacetate (salt); H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH.2CH3CO2H (Disulfide bridge: Cys3-Cys14); L-alanyl-glycyl-L-cysteinyl-L-lysyl-L-asparagyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-cysteine (3->14)-disulfide diacetic acid; Somatostatin diacetate. Grades: ≥95%. CAS No. 73977-20-5. Molecular formula: C76H104N18O19S2.2C2H4O2. Mole weight: 1757.99.
(Cys18)-Atrial Natriuretic Factor (4-18) amide (mouse, rabbit, rat) binds with high affinity to about 99% of ANF receptors in isolated rat perfusion kidneys. It competes effectively for binding sites with bioactive atrial peptides but has no agonist or antagonist effect on cGMP generation in cultured vascular smooth muscle and endothelial cells. Synonyms: C-ANF (4-23); H-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Cys-NH2 (Disulfide bridge: Cys4-Cys15); L-arginyl-L-seryl-L-seryl-L-cysteinyl-L-phenylalanyl-glycyl-glycyl-L-arginyl-L-isoleucyl-L-alpha-aspartyl-L-arginyl-L-isoleucyl-glycyl-L-alanyl-L-cysteinamide (4->15)-disulfide; (18-cysteinyl)-ANF (4-23)-NH2; Des(gln18,ser19,gly20,leu21,gly22)-atrial natriuretic peptide fragment 4-23 amide rat. Grades: 95%. CAS No. 111863-73-1. Molecular formula: C64H107N25O19S2. Mole weight: 1594.82.
D-allo-Thr(6)-Octreotide
D-allo-Thr(6)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: D-phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-D-allo-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); D-Phe-Cys-Phe-D-Trp-Lys-D-allo-Thr-Cys-Thr-ol (Disulfide Bridge between Cys2-Cys7); Octreotide EP impurity-A; L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-D-allo-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?7)-disulfide. CAS No. 1546983-12-3. Molecular formula: C49H66N10O10S2. Mole weight: 1019.25.
D-Arg(8)-AVP
D-Arg(8)-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: D-Arg(8)-Vasopressin; D-Arg-AVP; Vasopressin, 8-D-arginine-; H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-D-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-D-arginyl-glycinamide (1->6)-disulfide; 8-D-Argininevasopressin; D-Arginine-vasopressin; (D-Arg8)vasopressin. CAS No. 5591-81-1. Molecular formula: C46H65N15O12S2. Mole weight: 1084.24.
D-Asn(5)-AVP
D-Asn(5)-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: D-Asn-Vasopressin; D-Asn-AVP; H-Cys-Tyr-Phe-Gln-D-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-D-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide; Vasopressin, 5-D-asparagine-8-L-arginine-; 5-D-asparagine-Argipressin. CAS No. 2075715-46-5. Molecular formula: C46H65N15O12S2. Mole weight: 1084.24.
D-Cys(1)-AVP
D-Cys(1)-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: D-Cys(1)-Vasopressin; Vasopressin, 1-D-cysteine-8-L-arginine-; H-D-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); D-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide. CAS No. 66513-07-3. Molecular formula: C46H65N15O12S2. Mole weight: 1084.24.
D-Cys(2)-Octreotide
D-Cys(2)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: D-phenylalanyl-D-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); Octreotide Impurity-6; H-D-Phe-D-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol (Disulfide bridge: Cys2-Cys7); D-Phenylalanyl-D-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic (2?7)-disulfide; L-Cysteinamide, D-phenylalanyl-D-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?7)-disulfide, [R-(R*,R*)]-; L-Cysteinamide, D-phenylalanyl-D-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?7)-disulfide. CAS No. 108102-47-2. Molecular formula: C49H66N10O10S2. Mole weight: 1019.25.
D-Cys(4)-Terlipressin Trifluoroacetic Acid Salt
D-Cys(4)-Terlipressin Trifluoroacetic Acid Salt is an impurity of Terlipressin, which is a partial agonist of the vasopressin V1A receptor used as a vasoactive drug in the management of low blood pressure. Synonyms: (2S) -1-[ (4R, 7S, 10S, 13S, 16S, 19S) -19-[[2-[[2-[ (2-aminoacetyl) amino]acetyl]amino]acetyl]amino]-7- (2-amino-2-oxoethyl) -10- (3-amino-3-oxopropyl) -13-benzyl-16-[ (4-hydroxyphenyl) methyl]-6, 9, 12, 15, 18-pentaoxo-1, 2-dithia-5, 8, 11, 14, 17-pentazacycloicosane-4-carbonyl]-N-[ (2S) -6-amino-1-[ (2-amino-2-oxoethyl) amino]-1-oxohexan-2-yl]pyrrolidine-2-carboxamide Trifluoroacetic Acid Salt; H-Gly-Gly-Gly-D-Cys(1)-Tyr-Phe-Gln-Asn-Cys(1)-Pro-Lys-Gly-NH2.TFA; glycyl-glycyl-glycyl-D-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-lysyl-glycinamide (4->9)-disulfide TFA. Grades: >98%. Molecular formula: C52H74N16O15S2.xC2HF3O2. Mole weight: 1227.37 (free base).
D-Cys(6)-AVP
D-Cys(6)-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: D-Cys(6)-Vasopressin; Vasopressin, 6-D-cysteine-8-L-arginine-; H-Cys-Tyr-Phe-Gln-Asn-D-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-D-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide. CAS No. 163659-75-4. Molecular formula: C46H65N15O12S2. Mole weight: 1084.24.
D-Cys(7)-Octreotide
D-Cys(7)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: D-phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-D-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-D-Cys-Thr-ol (Disulfide bridge: Cys2-Cys7); D-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?7)-disulfide. CAS No. 1211530-36-7. Molecular formula: C49H66N10O10S2. Mole weight: 1019.25.
(Deamino-Cys1,Arg8)-Vasopressin
(Deamino-Cys1,Arg8)-Vasopressin is used to treat diabetes insipidus, bedwetting, hemophilia A, von Willebrand disease, and high blood urea levels. Synonyms: 3-Mercaptopropionyl-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); deamino-Cys(1)-Tyr-Phe-Gln-Asn-Cys(1)-Pro-Arg-Gly-NH2; deamino-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide; Glycinamide, N-(3-mercapto-1-oxopropyl)-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-arginyl-, cyclic (1?5)-disulfide; Vasopressin, 1-(3-mercaptopropanoic acid)-8-L-arginine-; 1-Deamino-8-L-arginine-vasopressin; 1-Desamino-L-arginine vasopressin; 8-Arginine-deaminovasopressin; [1-β-Mercaptopropionic acid,8-arginine]vasopressin; DAVP; Desamino-Arg8-vasopressin. Grades: ≥90%. CAS No. 113-81-5. Molecular formula: C46H64N14O12S2. Mole weight: 1069.22.
(Deamino-Cys1,β-cyclohexyl-Ala4,Dab8)-Vasopressin
The introduction of Cha produces agonists for human V1b receptors. Synonyms: d[Cha4,Dab8]-AVP; 3-Mercaptopropionyl-Tyr-Phe-β-cyclohexyl-Ala-Asn-Cys-Pro-Dab-Gly-NH2 (Disulfide bridge: Cys1-Cys6); deamino-Cys(1)-Tyr-Phe-Cha-Asn-Cys(1)-Pro-Dab-Gly-NH2; deamino-cysteinyl-L-tyrosyl-L-phenylalanyl-3-cyclohexyl-L-alanyl-L-asparagyl-L-cysteinyl-L-prolyl-3-aminomethyl-L-alanyl-glycinamide (1->6)-disulfide; d[Cha4,Dab8]VP; N-{(2S)-4-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxobutan-2-yl}-1-{[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-benzyl-10-(cyclohexylmethyl)-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-prolinamide. Grades: ≥90%. CAS No. 929294-77-9. Molecular formula: C48H67N11O11S2. Mole weight: 1038.25.
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