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| Product | Description | |
|---|---|---|
| 3,4-Dihydroxystyrene | It is produced by the strain of Fomes tasmanicus. It inhibits the activity of Hydroxylases including tyrosine, tryptophan and phenylalanine. Uses: A metabolite of styrene (s687790). Synonyms: 4-Vinylbenzene-1,2-diol; 4-Vinylcatechol; 2-hydroxy-4-vinylphenol; 3,4-Dihydroxy Styrene; Vinylcatechol. Grades: ≥95%. CAS No. 6053-2-7. Molecular formula: C8H8O2. Mole weight: 136.15. |  |
| 4-Chloro-DL-phenylalanine | 4-Chloro-DL-phenylalanine is a pharmaceutical intermediate. It acts as a selective and irreversible inhibitor of tryptophan hydroxylase. It is a rate-limiting enzyme in the biosynthesis of serotonin. It has been used experimentally to treat carcinoid syndrome. It is used in scientific research in humans and animals to investigate the effects of serotonin depletion. It binds irreversibly to tryptophan hydroxylase to cause depletion of serotonin in the brain. Uses: 4-chloro-dl-phenylalanine has been used experimentally to treat carcinoid syndrome. it is used in scientific research in humans and animals to investigate the effects of serotonin depletion. it binds irreversibly to tryptophan hydroxylase to cause depletion of serotonin in the brain. Synonyms: CP-10,188; CP10,188; CP 10,188; CP-10188; CP10188; CP 10188; Fenclonine; DL-3-(4-Chlorophenyl)alanine; Fenclonin; NSC 77370; p-Clorophenylalanine.; DL-4-Chlorophenylalanine;p-Chlorophenylalanine;(S)-2-amino-3-(4-chlorophenyl)propanoic acid;2-Amino-3-(4-chlorophenyl)propanoic acid; DL-3-(4-Chlorophenyl)alanine; Fenclonin; Fenclonine; PCP; PCPA; CP-10188. Grades: ≥ 99% (HPLC). CAS No. 7424-00-2. Molecular formula: C9H10ClNO2. Mole weight: 199.63. | |
| 4-Chloro-DL-phenylalanine methyl ester hydrochloride | 4-Chloro-DL-phenylalanine methyl ester hydrochloride is a tryptophan hydroxylase (TPH) inhibitor and a serotonin synthesis inhibitor. 4-Chloro-DL-phenylalanine methyl ester hydrochloride is also known to induce memory deficits in rats. Synonyms: DL-Phe(4-Cl)-OMe HCl; p-Chloro-DL-Phe-OMe HCl; (RS)-2-Amino-3-(4-chlorophenyl)propionic acid methyl ester hydrochloride; methyl 2-amino-3-(4-chlorophenyl)propanoate hydrochloride; H-DL-Phe(4-Cl)-OMe HCl; DL-p-Chlorophenylalanine methyl ester hydrochloride; DL-4-Chlorophenylalanine methyl ester hydrochloride; H-p-Chloro-D-Phe-OMe HCl. Grades: ≥ 99% (HPLC). CAS No. 14173-40-1. Molecular formula: C10H12ClNO2·HCl. Mole weight: 250.12. | |
| 4-Chloro-D-phenylalanine | 4-Chloro-D-phenylalanine is an inhibitor of liver tryptophan-5-hydroxylase. A specific depletor of brain serotonin. Synonyms: D-Phe(4-Cl)-OH; p-Chloro-D-phenylalanine; (R)-2-Amino-3-(4-chlorophenyl)propionic acid; D-4-Chlorophenylalanine; D-Phenylalanine, 4-chloro-; H-D-PHE(4-CL)-OH; (R)-2-AMINO-3-(4-CHLOROPHENYL)PROPANOIC ACID; (2R)-2-amino-3-(4-chlorophenyl)propanoic acid; d-p-chlorophenylalanine; (R)-fenclonine. Grades: ≥ 99% (HPLC). CAS No. 14091-08-8. Molecular formula: C9H10ClNO2. Mole weight: 199.63. | |
| 4-Chloro-D-phenylalanine methyl ester hydrochloride | 4-Chloro-D-phenylalanine Methyl Ester Hydrochloride is one of the enatiomer in 4-Chloro-DL-phenylalanine Methyl Ester Hydrochloride which is a tryptophan hydroxylase (TPH) inhibitor and a serotonin synthesis inhibitor. 4-Chloro-D-phenylalanine methyl ester hydrochloride is also known to induce memory deficits in rats. Synonyms: D-Phe(4-Cl)-OMe HCl; p-Chloro-D-Phe-OMe HCl; (R)-2-amino-3-(4-chlorophenyl)propionic acid methyl ester hydrochloride; H-D-Phe(4-Cl)OMe HCl; D-Phenylalanine, 4-chloro-, methyl ester, hydrochloride; D-Methyl 4-chlorophenylalaninate hydrochloride; 4-Chloro-D-phenylalanine methyl ester hydrochloride; 4-Chloro-D-Phe-OMe HCl. Grades: ≥ 98% (HPLC). CAS No. 33965-47-8. Molecular formula: C10H12ClNO2·HCl. Mole weight: 250.12. | |
| 4-Chloro-L-phenylalanine | 4-Chloro-L-phenylalanine (L-PCPA) is a 5-HT biosynthesis inhibitor. 4-Chloro-L-phenylalanine is also a nonspecific antagonist of both isoforms of tryptophan hydroxylase ( TPH1 and TPH2 ) [1]. Uses: Scientific research. Group: Peptides. Alternative Names: L-PCPA. CAS No. 14173-39-8. Pack Sizes: 1 g; 5 g. Product ID: HY-W019599. |  |
| 6,7-Dimethyl-5,6,7,8-tetrahydropterine hydrochloride | 6,7-Dimethyl-5,6,7,8-tetrahydropterine hydrochloride is a synthetic reduced pterin cofactor for nitric oxide synthetase, and for phenylalanine, tyrosine, and tryptophan hydroxylases; less active than the natural cofactor, tetrahydrobiopterin (BH4). Applications: A synthetic reduced pterin cofactor. Group: Coenzymes. Synonyms: DMPH4; 2-Amino-6,7-dimethyl-4-hydroxy-5,6,7,8-tetrahydropteridine. CAS No. 945-43-7. Purity: ≥95%. Mole weight: 231.68. Appearance: Powder. Form: Solid. DMPH4; 2-Amino-6,7-dimethyl-4-hydroxy-5,6,7,8-tetrahydropteridine; 6,7-Dimethyl-5,6,7,8-tetrahydropterine hydrochloride; 945-43-7. Cat No: COEC-094. |  |
| (±)-6-Methyl-5,6,7,8-tetrahydropterine dihydrochloride | (±)-6-Methyl-5,6,7,8-tetrahydropterine dihydrochloride is a synthetic cofactor for tyrosine hydrolase, phenylalanine and tryptophan hydroxylases. (±)-6-Methyl-5,6,7,8-tetrahydropterine dihydrochloride has less activity than the natural cofactor, BH4. Applications: A synthetic cofactor for tyrosine hydrolase. Group: Coenzymes. CAS No. 69113-63-9. Mole weight: 254.12. Appearance: Powder. Form: Solid. (±)-6-Methyl-5,6,7,8-tetrahydropterine dihydrochloride; 69113-63-9. Cat No: COEC-081. | |
| (6R)-5,6,7,8-Tetrahydro-L-biopterin 2HCl | Tetrahydrobiopterin is a naturally occurring essential cofactor of the three aromatic amino acid hydroxylase enzymes, used in the degradation of amino acid phenylalanine and in the biosynthesis of the neurotransmitters serotonin, melatonin, dopamine, norepinephrine , epinephrine, and is a cofactor for the production of nitric oxide by the nitric oxide synthases. Chemically, its structure is that of a reduced pteridine derivative. Group: Biochemicals. Alternative Names: (6R)-5,6,7,8-Tetrahydrobiopterin dihydrochloride; 6R-BH4; Sapropterin; Sapropterin dihydrochloride; BioMarin T 1401, Biopten, Kuvan, SUN 0588; Shiratori SN 0588. Grades: Highly Purified. CAS No. 69056-38-8,17528-72-2. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C?H??N?O?; 2(HCl), Molecular Weight: 314.17. US Biological Life Sciences. |  Worldwide |
| (6R)-Tetrahydro-L-biopterin-d3 Sulfate(Mixture of Diastereomers) | (6R)-Tetrahydro-L-biopterin-d3 Sulfate(Mixture of Diastereomers) is the labeled R-enantiomer of Tetrahydro-L-biopterin. It is a natural cofactor for phenylalanine hydroxylase, tryptophan hydroxylase, tyrosine hydroxylase, and nitric oxide synthase. An essential cofactor for the production of neurotransmitters such as catecholamines, serotonin, and nitric oxide. Increasing BH4 levels boosts sensitivity to pain. Applications: A natural cofactor for phenylalanine hydroxylase. Group: Coenzymes. CAS No. 103130-44-5 (unlabeled). Mole weight: 342.34. (6R)-Tetrahydro-L-biopterin-d3 Sulfate(Mixture of Diastereomers); 103130-44-5 (unlabeled). Cat No: COEC-090. | |
| (6R)-Tetrahydro-L-biopterin Sulfate | (6R)-Tetrahydro-L-biopterin Sulfate is a natural cofactor for tyrosine hydroxylase, phenylalanine hydroxylase, tryptophan hydroxylase, and nitric oxide synthase. It is also an essential cofactor in the the production of neurotransmitters such as catecholamines, serotonin, and nitric oxide. Applications: An essential cofactor in the the production of neurotransmitters. Group: Coenzymes. CAS No. 103130-44-5. Mole weight: 339.33. Form: Solid. (6R)-Tetrahydro-L-biopterin Sulfate; 103130-44-5. Cat No: COEC-074. | |
| LX-1031 | LX-1031 is a heterocyclic substituted phenylalanine analog, an oral small molecule tryptophan hydroxylase (TPH) inhibitor that reduces synthesis of serotonin (5-HT) peripherally. It is being developed for conditions characterized by excess 5-HT expression such as diarrhea-predominant irritable bowel syndrome (IBS-D) and, possibly, carcinoid diarrhea. Synonyms: LX-1031; LX 1031; LX1031. Grades: >98%. CAS No. 945976-76-1. Molecular formula: C28H25F3N4O4. Mole weight: 538.52. | |
| PCPA methyl ester hydrochloride | PCPA methyl ester hydrochloride (4-Chloro-DL-phenylalanine methyl ester hydrochloride), a reversible tryptophan hydroxylase inhibitor, is a serotonin (5-HT) synthesis inhibitor. PCPA methyl ester hydrochloride crosses the blood brain barrier and reduces 5-HT central availability [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4-Chloro-DL-phenylalanine methyl ester hydrochloride. CAS No. 14173-40-1. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-101456. | |
| phenylalanine 3-monooxygenase | The enzyme from the bacterium Streptomyces coeruleorubidus forms 3-hydroxy-L-phenylalanine (i.e. m-L-tyrosine), which is one of the building blocks in the biosynthesis of the uridyl peptide antibiotics pacidamycins. Group: Enzymes. Synonyms: PacX; phenylalanine 3-hydroxylase. Enzyme Commission Number: EC 1.14.16.7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0959; phenylalanine 3-monooxygenase; EC 1.14.16.7; PacX; phenylalanine 3-hydroxylase. Cat No: EXWM-0959. | |
| phenylalanine 4-monooxygenase | The active centre contains mononuclear iron(II). The reaction involves an arene oxide that rearranges to give the phenolic hydroxy group. This results in the hydrogen at C-4 migrating to C-3 and in part being retained. This process is known as the NIH-shift. The 4a-hydroxytetrahydrobiopterin formed can dehydrate to 6,7-dihydrobiopterin, both spontaneously and by the action of EC 4.2.1.96, 4a-hydroxytetrahydrobiopterin dehydratase. The 6,7-dihydrobiopterin can be enzymically reduced back to tetrahydrobiopterin, by EC 1.5.1.34, 6,7-dihydropteridine reductase, or slowly rearranges into the more stable compound 7,8-dihydrobiopterin. Group: Enzymes. Synonyms: phenylalaninase; phenylalanine 4-hydroxylase; phenylalanine hydroxylase. Enzyme Commission Number: EC 1.14.16.1. CAS No. 9029-73-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0953; phenylalanine 4-monooxygenase; EC 1.14.16.1; 9029-73-6; phenylalaninase; phenylalanine 4-hydroxylase; phenylalanine hydroxylase. Cat No: EXWM-0953. | |
| phenylalanine N-monooxygenase | A heme-thiolate protein (P-450). This enzyme catalyses two successive N-hydroxylations of L-phenylalanine, the first committed steps in the biosynthesis of benzylglucosinolate. The product of the two hydroxylations, N,N-dihydroxy-L-phenylalanine, is extremely labile and dehydrates spontaneously.The dehydrated product is then subject to a decarboxylation that produces the oxime. It is still not known whether the decarboxylation is spontaneous or catalysed by the enzyme. The product, (E)-phenylacetaldoxime, undergoes a spontaneous isomerization to the (Z) form. Group: Enzymes. Synonyms: phenylalanine N-hydroxylase; CYP79A2. Enzyme Commission Number: EC 1.14.13.124. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0725; phenylalanine N-monooxygenase; EC 1.14.13.124; phenylalanine N-hydroxylase; CYP79A2. Cat No: EXWM-0725. | |
| Sapropterin dihydrochloride | Sapropterin ((6R)-BH4) is an orally active phenylalanine hydroxylase (PAH) cofactor, which is effective in reducing blood phenylalanine concentrations. Sapropterin also drives autoimmunity. Sapropterin can be used in study of phenylketonuria (PKU) [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (6R)-BH4 dihydrochloride; (6R)-Tetrahydro-L-biopterin dihydrochloride. CAS No. 69056-38-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-A0124A. | |
| Sapropterin dihydrochloride | Sapropterin is a naturally occurring cofactor for phenylalanine hydroxylase. Under the trade name Kuvan, sapropterin dihydrochloride is approved for the treatment of hyperphenylalaninaemia and tetrahydrobiopterin deficiency. Synonyms: BioMarin T 1401; Biopten; Kuvan; SUN 0588; Shiratori SN 0588; (6R)-5,6,7,8-Tetrahydrobiopterin Dihydrochloride; Phenoptin; (R)-2-Amino-6-((1R,2S)-1,2-dihydroxypropyl)-5,6,7,8-tetrahydropteridin-4(3H)-one dihydrochloride; (6R)-Tetrahydrobiopterin hydrochloride; (6R)-5,6,7,8-Tetrahydro-L-Biopterin Dihydrochloride. Grades: >98%. CAS No. 69056-38-8. Molecular formula: C9H17Cl2N5O3. Mole weight: 314.17. | |
| Sapropterin Dihydrochloride | Tetrahydrobiopterin (BH4, THB), also known as sapropterin, is a naturally occurring essential cofactor of the three aromatic amino acid hydroxylase enzymes, used in the degradation of amino acid phenylalanine and in the biosynthesis of the neurotransmitters serotonin (5-hydroxytryptamine, 5-HT), melatonin, dopamine, norepinephrine (noradrenaline), epinephrine (adrenaline), and is a cofactor for the production of nitric oxide (NO) by the nitric oxide synthases.[1] Chemically, its structure is that of a reduced pteridine derivative. Group: Biochemicals. Alternative Names: (6R)-5,6,7,8-Tetrahydrobiopterin dihydrochloride; 6R-BH4. CAS No. 17528-72-2. Pack Sizes: 50mg, 100mg, 250mg. US Biological Life Sciences. | Worldwide |
| Sapropterin Related Compound ((6S)-5,6,7,8-Tetrahydro-L-Biopterin Sulfate) | An impurity of Sapropterin.Sapropterin is an cofactor for phenylalanine hydroxylase. Synonyms: 4(1H)-Pteridinone, 2-amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-, [6S-[6R*(1S*,2R*)]]-, sulfate (1:x) (salt); (S)-2-Amino-6-((1R,2S)-1,2-dihydroxypropyl)-5,6,7,8-tetrahydropteridin-4(1H)-one sulfate (1:x); (6S)-5,6,7,8-Tetrahydro-L-erythro-biopterin sulfate; [6S-[6R*(1S*,2R*)]]-2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4(1H)-pteridinone sulfate (1:x) (salt); (6S)-Tetrahydro-L-biopterin sulfate salt. Grades: ≥95%. CAS No. 109784-74-9. Molecular formula: C9H15N5O3.xH2SO4. Mole weight: 241.25 (free base). | |
| trans-cinnamate 2-monooxygenase | This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of one atom o oxygen into the other donor. The systematic name of this enzyme class is trans-cinnamate,NADPH:oxygen oxidoreductase (2-hydroxylating). Other names in common use include cinnamic acid 2-hydroxylase, cinnamate 2-monooxygenase, cinnamic 2-hydroxylase, cinnamate 2-hydroxylase, and trans-cinnamic acid 2-hydroxylase. This enzyme participates in phenylalanine metabolism and phenylpropanoid biosynthesis. Group: Enzymes. Synonyms: cinnamic acid 2-hydroxylase; cinnamate 2-monooxygenase; cinnamic 2-hydroxylase; cinnamate 2-hydroxylase; trans-cinnamic acid 2-hydroxylase. Enzyme Commission Number: EC 1.14.13.14. CAS No. 53126-56-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0739; trans-cinnamate 2-monooxygenase; EC 1.14.13.14; 53126-56-0; cinnamic acid 2-hydroxylase; cinnamate 2-monooxygenase; cinnamic 2-hydroxylase; cinnamate 2-hydroxylase; trans-cinnamic acid 2-hydroxylase. Cat No: EXWM-0739. | |
| 3,4-Dihydroxy-L-phenylalanine | Precursor of catecholamine neurotransmitters; anti-parkinsonian therapy. Natural isomer of the immediate precursor of dopamine; product of tyrsine hydroxylase. Group: Biochemicals. Alternative Names: Levodopa; L-3-Hydroxytyrosine; 3-Hydroxy-L-tyrosine; (-)-3-(3,4-Dihydroxyphenyl)-L-alanine; Bendopa; Deadopa; Dopaflex; Dopal; Dopaidan; Dopalina; Dopar. Grades: Highly Purified. CAS No. 59-92-7. Pack Sizes: 50g, 100g, 250g, 500g, 1Kg. Molecular Formula: C9H11NO4, Molecular Weight: 197.19. US Biological Life Sciences. | Worldwide |
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