Proteinase K Suppliers USA
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Product | Description | |
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Proteinase K Quick inquiry Where to buy Suppliers range | 100mg Pack Size. Group: Biochemicals, Diagnostic Raw Materials, Research Organics & Inorganics. Formula: C29H27N2O12P. CAS No. 39450-01-6. Prepack ID 49085587-100mg. Molecular Weight 626.5. See USA prepack pricing. | |
Proteinase K Quick inquiry Where to buy Suppliers range | Proteinase K. Group: Heterocyclic Organic Compound. Grades: Protein purity >90%. CAS No. 39450-01-6. Product ID: ACM39450016. Molecular formula: n.a. | |
Proteinase K Quick inquiry Where to buy Suppliers range | Proteinase K, Improve cloning efficiency of PCR products. Proteinase k is useful in the isolation of the DNA and RNA. CAS No. 39450-01-6. Ebrator Biochemicals provides scientists around the global scientific community with a wide range of high purity Life Science products & Fine Chemicals. Categories: Proteinase K. | |
1,4-Diaminoanthraquinone Quick inquiry Where to buy Suppliers range | An anthraquinone derivative that is a potent and selective protein kinase CK1 delta inhibitor. Studies suggest that it has potential solar cell applications. Used in studies as a potential competitive non-peptidic inhibitor of HIV-1 proteinase. Group: Biochemicals. Alternative Names: 1,4-Diamino-9,10-anthraquinone; Acetate Red Violet R; Acetoquinone Light Heliotrope NL; Acetylon Fast Red Violet R; Akasperse Violet 3R; Amacel Heliotrope R; Cibacet Violet 2R; C.I. 61100; NSC 63807; NSC 7833; Krisolamine; Violet 14447. Grades: Highly Purified. CAS No. 128-95-0. Pack Sizes: 2.5g. US Biological Life Sciences. | Worldwide |
Ac-DEVD-CHO Quick inquiry Where to buy Suppliers range | Ac-DEVD-CHO is a potent aldehyde inhibitor of Group II caspases with Ki values of 0.2 nM and 0.3 nM for for caspase-3 and caspase-7, respectively. Weak inhibition for caspase-2. Uses: Cysteine proteinase inhibitors. Synonyms: N-acetyl-asp-glu-val-asp-al; Ac-Asp-Glu-Val-Asp-Aldehyde; L-Valinamide,N-acetyl-L-a-aspartyl-L-a-glutamyl-N-(2-carboxy-1-formylethyl)-. Grades: 95 %. CAS No. 169332-60-9. Molecular formula: C20H30N4O11. Mole weight: 502.47. | |
Adenovirus Proteinase Inhibitor, NSC 37249 (2- (Dicyclohexylamino) -N- (4- (4- ( (2- (dicyclohexylamino) acetyl) amino) phenyl) sulfonylphenyl) acetamide, N, N?- (Sulfonyldi-4, 1-phenylene) bis (2- (dicyclohexylamino) acetamide, AVP Inhibitor) Quick inquiry Where to buy Suppliers range | A sulfonyl diphenyl ene -bis-dicyclohexyl aminoacetamide compound that acts as a potent and selective inhibitor against adenovirus cysteine proteinase AVP by targeting simultaneously AVP co-factor pVIc (GVQSLKRRRCF) N-terminal binding pocket (Ki = 150nM) and AVP-pVIc substrate-binding site (Ki = 400nM), blocking both AVP-pVIc active complex formation (IC50 = 140nM; [substrate] = 5uM & [pVIc] = 40uM) and catalytic activity (IC50 = 490nM; [substrate] = 5uM) without affecting trypsin or papain protease activity even at concentrations as high as 10uM. Group: Biochemicals. Grades: Purified. CAS No. 2907-88-2. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?S. US Biological Life Sciences. | Worldwide |
Aprotinin, Bovine (Pancreatic trypsin inhibitor) Quick inquiry Where to buy Suppliers range | Aprotinin is a competitive serine protease inhibitor that inhibits trypsin, chymotrypsin, kallikrein and plasmin. Aprotinin forms stable complexes with and blocks the active sites of enzymes. Binding is reversible with most aprotinin-protease complexes, dissociating at pH >10 or <3. Effective concentration is equimolar with protease. Group: Biochemicals. Alternative Names: Antikrein; Antilysin; Antilysine; Aprostat; Aprotinin; BPTI; BPTI Trypsin Inhibitor; Basic Pancreatic Trypsin Inhibitor; Bayer A 128; Bovine Basic Pancreatic Trypsin Inhibitor; Bovine Pancreatic Trypsin Inhibitor; Bovine Trypsin Inhibitor; Fosten; Kallikrein-trypsin Inactivator; Kiker 52G; Kir Richter; Kunitz Pancreatic Trypsin Inhibitor; Kunitz Protease Inhibitor; Kunitz Trypsin Inhibitor; Kunitz-type Inhibitor; Kunitz-type Proteinase Inhibitor; Kunitz-type Trypsin Inhibitor; Onquinin; Pancreatic Basic Trypsin Inhibitor; Pancreatic Trypsin Inhibitor; Pancreatic Trypsin Inhibitor (Kunitz); Protease Inhibitor, Kunitz Type; RP 9921; Repulson; Trasuylol; Trasylol; Trazinin; Triazinin; Trypsin Inhibitor, Trasylol; Trypsin-kallikrein Inhibitor (Kunitz); Zymofren. Grades: Highly Purified. CAS No. 9087-70-1. Pack Sizes: 100mg, 250mg, 500mg, 1g. Molecular Formula: C???H???N??O??S?, Molecular Weight: 6511.45. US Biological Life Sciences. | Worldwide |
Benzamidine hydrochloride Quick inquiry Where to buy Suppliers range | Benzamidine is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin (Kis = 35, 350, and 220 μM, respectively). Benzamidine inhibits the autoactivation of human blood coagulation factor VII, useful as a tool for studying the interactions between this and other relevant growth factors. Uses: Serine proteinase inhibitors. Synonyms: Benzenecarboximidamide, hydrochloride (1:1); Benzamidine, monohydrochloride; Benzenecarboximidamide, monohydrochloride; Amidinobenzene hydrochloride; Benzamidinium chloride; Benzimidamide hydrochloride. Grades: ≥98%. CAS No. 1670-14-0. Molecular formula: C7H8N2.HCl. Mole weight: 156.61. | |
CA 074 Quick inquiry Where to buy Suppliers range | CA 074 is a potent and selective inhibitor of cathepsin B (Ki = 2-5 nM). It reduces bone metastasis in a 4T1.2 breast cancer model. Uses: Cysteine proteinase inhibitors. Synonyms: CA-074; CA074; CA 074; N-[[(2S,3S)-3-[(Propylamino)carbonyl]-2-oxiranyl]carbonyl]-L-isoleucyl-L-proline. Grades: ≥98% by HPLC. CAS No. 134448-10-5. Molecular formula: C18H29N3O6. Mole weight: 383.44. | |
Calpain Inhibitor II Quick inquiry Where to buy Suppliers range | Calpain inhibitor II is a cell-permeable inhibitor of calpain I (Ki = 120 nM), calpain II (Ki = 230 nM), cathepsin B (Ki = 100 nM), and cathepsin L (Ki = 600 pM). It inhibits activation-induced programmed cell death and restores defective immune responses in HIV+ donors. Calpain inhibitor II can block nitric oxide production by interfering with transcription of the inducible nitric oxide synthase gene, which is a weak inhibitor of proteasome. It has been used to demonstrate the involvement of ubiquitin-proteasome protein degradation in various biological systems. Uses: Cysteine proteinase inhibitors. Synonyms: L-Leucinamide, N-acetyl-L-leucyl-N-[(1S)-1-formyl-3-(methylthio)propyl]-; L-Leucinamide, N-acetyl-L-leucyl-N-[1-formyl-3-(methylthio)propyl]-, (S)-; N-Acetyl-L-leucyl-N-[(1S)-1-formyl-3-(methylthio)propyl]-L-leucinamide; ALLM; Calp II; CI 2; SUAM 312; N-acetylleucyl-leucyl-methioninal; Ac-Leu-Leu-Met-al; N-acetyl-L-leucyl-L-leucyl-L-methioninal. Grades: ≥98%. CAS No. 110115-07-6. Molecular formula: C19H35N3O4S. Mole weight: 401.57. | |
Calpeptin Quick inquiry Where to buy Suppliers range | Calpeptin is a potent, cell-permeable calpain inhibitor with ID50 of 52 nM, 34 nM, 138 nM, and 40 nM for Calpain I (porcine erythrocytes), Calpain II (porcine kidney), Papainb, and Calpain I (human platelets), respectively. Uses: Cysteine proteinase inhibitors. Synonyms: Benzylcarbonyl-leu-nleu-H; Cbz-Leu-Nle-al. Grades: >98%. CAS No. 117591-20-5. Molecular formula: C20H30N2O4. Mole weight: 362.46. | |
Chymostatin Quick inquiry Where to buy Suppliers range | Chymostatin is a bioactive peptide that acts as a protease inhibitor with selectivity for chymotryptase-like serine proteases. It potently inhibits chymotrypsin and chymase, but it cannot block the activity of cathepsins, papain, and leukocyte elastase effectively. It doesn't have effect on trypsin, thrombin, plasmin, pepsin, and kallikrein. Uses: Serine proteinase inhibitors. Synonyms: [(S)-1-Carboxy-2-phenylethyl]-carbamoyl-a-[2-amidohexahydro-4(S)-pyrimidyl]-(S)-glycyl-[A= Leu B=Val C=Ile]-phenylalaninal (Mixture). Grades: ≥95% (a mixture of A, B, C). CAS No. 9076-44-2. Molecular formula: CxHyN7O6. Mole weight: 607.7. | |
Ebrator Biochemicals Inc. Quick inquiry Where to buy Suppliers range | Manufacturer of impurities, indicators, stains, dyes, fine and biochemicals. L-lactic, glutamic, citric, lauric, linoleic, myristic, and amino acids. Products include starch, chitin, borax, albumin, protein, casein and glycine. Lipids, pH buffers, enzymes, carbohydrates, proteinase K, inorganic and substrates are offered. Corn, olive, sesame, mineral and light white oils are available. L-tyrosine, L-leucine, ammonium sulfate, disodium phosphate, barium acetate, potassium chloride and sodium are provided. Specimen bags are also offered. Suitable for diagnostic, academic and research institutions. Secondary services include packaging, labeling and filling. Serves pharmaceutical, government, biotech and healthcare industries. | |
Leupeptin Quick inquiry Where to buy Suppliers range | Leupeptin reversibly inhibits serine proteinases (trypsin (Ki=3.5 nM), plasmin (Ki= 3.4 nM), porcine kallikrein), and cysteine proteinases (papain, cathepsin B (Ki = 4.1 nM), endoproteinase Lys-C). Leupeptin has been shown to inhibit activation-induced programmed cell death. Synonyms: 2-(2-acetamido-4-methylvaleramido)-n-(1-formyl-4-guanidinobutyl)-4-methylval; 2-(2-acetamido-4-methylvaleramido)-n-(1-formyl-4-guanidinobutyl)-4-valeramid; leupeptinac-ll; l-leucinamide,n-acetyl-l-leucyl-n-(4-((aminoiminomethyl)amino)-1-formylbutyl; Leupeptin; Leupeptin Ac-LL; N-Acetyl-L-leucyl-L-leucyl-L-argininal; NK-381; NK 381; NK381. Grades: >98%. CAS No. 24365-47-7. Molecular formula: C20H38N6O4. Mole weight: 426.55. | |
L-Valine chloromethyl ketone hydrochloride Quick inquiry Where to buy Suppliers range | L-Valine chloromethyl ketone hydrochloride acts as a reagent in the preparation of tetrapeptidyl chloromethyl ketones, which are potent inhibitors of proteinase K. Synonyms: L-Val-CMK HCl; H-Val CH2Cl HCl; H-L-Val-CMK HCl; (3S)-3-amino-1-chloro-4-methylpentan-2-one hydrochloride; L Val CMK HCl; H L Val CMK HCl. Grades: ≥ 97%. CAS No. 107831-79-8. Molecular formula: C6H12ClNO·HCl. Mole weight: 186.10. | |
NK314 Quick inquiry Where to buy Suppliers range | NK314 is a novel synthetic benzo[c]phenanthridine alkaloid that shows strong antitumor activity. It inhibited topoisomerase II activity and stabilized topoisomerase II-DNA cleavable complexes. The DNA breaks occurred within 1h after treatment with NK314 even without digestion of topoisomerase II by proteinase K, whereas etoposide required digestion of the enzyme protein in cleavable complex to detect DNA breaks. Pretreatment with topoisomerase II catalytic inhibitors, ICRF-193 and suramin, reduced both cleavable complex-mediated DNA breaks and proteinase K-independent DNA breaks, but protease inhibitors and nuclease inhibitors only decreased the latter. These results indicate that NK314 might affect topoisomerase II in the different manner from cleavable complex formation and activate intracellular proteinase and nuclease to produce DNA fragmentation. As a result of this unique mechanism of DNA breakage, NK314 showed substantial growth inhibition of topoisomerase II inhibitor-resistant tumors. Synonyms: NK-314; NK 314. Grades: 98%. CAS No. 208237-49-4. Molecular formula: C22H18ClNO4. Mole weight: 395.84. | |
Prion Protein (106-126) (human) (scrambled) Quick inquiry Where to buy Suppliers range | Prion Protein (106-126) (human) (scrambled) is a scrambled sequence of human prion protein (106-126), which is an important control for studying the biological activity of prion protein peptides. According to circular dichroism analysis, the scrambled PrP 106-126 shows a random coil structure without aggregation, and is completely degraded after incubation with proteinase K and pronase for 30 minutes at 37°C. Synonyms: H-Asn-Gly-Ala-Lys-Ala-Leu-Met-Gly-Gly-His-Gly-Ala-Thr-Lys-Val-Met-Val-Gly-Ala-Ala-Ala-OH; L-asparagyl-glycyl-L-alanyl-L-lysyl-L-alanyl-L-leucyl-L-methionyl-glycyl-glycyl-L-histidyl-glycyl-L-alanyl-L-threonyl-L-lysyl-L-valyl-L-methionyl-L-valyl-glycyl-L-alanyl-L-alanyl-L-alanine; Prion Protein Fragment 106-126 Scrambled Human; PrP (106-126) (human) (scrambled). Grades: ≥90%. CAS No. 150469-23-1. Molecular formula: C80H138N26O24S2. Mole weight: 1912.24. | |
Prohormone Convertase 2 (PC2) Quick inquiry Where to buy Suppliers range | PC2 is a soluble, Ca 2+ -dependent serine proteinase of the subtilisin-kexin type, exhibiting an acidic pH optimum. Uses: API. Product ID: 10-101-300. | |
Protease-Activated Receptor-2, amide Quick inquiry Where to buy Suppliers range | SLIGKV-NH2 is a protease-activated receptor 2 (PAR2) agonist (Ki = 9.64 μM; IC50 = 10.4 μM). Synonyms: Thrombin Receptor-Like 1 (1-6) amide (human); SLIGKV amide; Proteinase Activated Receptor 2 (1-6) amide (human); Coagulation Factor II Receptor-Like 1 (1-6) amide (human); Ser-Leu-Ile-Gly-Lys-Val; PAR2 activating peptide; PAR2-AP; PAR-2 (1-6) Human; L-seryl-L-leucyl-L-isoleucyl-glycyl-L-lysyl-L-valinamide. Grades: 98%. CAS No. 190383-13-2. Molecular formula: C28H54N8O7. Mole weight: 614.78. | |
Sivelestat sodium tetrahydrate Quick inquiry Where to buy Suppliers range | Sivelestat is a competitive human neutrophil elastase (HNE) inhibitor (IC50 = 44 nM, Ki = 0.2 μM). It also inhibits leukocyte elastase obtained from rabbit, rat, hamster and mouse (IC50 = 19 to 49 nM). However, it does not inhibit trypsin, thrombin, plasmin, plasma kallikrein, pancreas kallikrein, chymotrypsin and cathepsin G even at 100 μM. In in-vivo studies, it suppressed lung hemorrhage in hamster (ID50 = 82 μg/kg) by intratracheal administration and increase of skin capillary permeability in guinea pig (ID50 = 9.6 mg/kg) by intravenous administration, both of which were induced by human neutrophil elastase. Uses: Serine proteinase inhibitors. Synonyms: EI546 sodium tetrahydrate; EI 546 sodium tetrahydrate; EI-546 sodium tetrahydrate; LY544349 sodium tetrahydrate; LY 544349 sodium tetrahydrate; LY-544349 sodium tetrahydrate; ONO5046 sodium tetrahydrate; ONO 5046 sodium tetrahydrate; ONO-5046 sodium tetrahydrate. Grades: >98%. CAS No. 201677-61-4. Molecular formula: C20H29N2NaO11S. Mole weight: 528.51. | |
Suc-Leu-Leu-Val-Tyr-AMC Quick inquiry Where to buy Suppliers range | Suc-Leu-Leu-Val-Tyr-AMC is a fluorogenic substrate of calpains and 20S proteasome and used to study the activity of calpains and proteosomal degradation. It is also a substrate for carboxypeptidase Y, proteinase yscE (kexin), ingensin, as well as for porcine calpain isozymes I and II and for papain. Uses: Peptide Inhibitors. CAS No. 94367-21-2. Product ID: R0808. | |
Tosyllysine chloromethyl ketone hydrochloride Quick inquiry Where to buy Suppliers range | Tosyllysine chloromethylketone (TLCK) is an inhibitor of serine proteinases. It inhibits mitochondrial damage and cell death. Uses: Serine proteinase inhibitors. Synonyms: 1-Chloro-3-Toxylamide-7-Amino-L-2-Heptanone hydrochloride; TLCK hydrochloride; TLCK HCl; (S)-N-(7-Amino-1-chloro-2-oxoheptan-3-yl)-4-methylbenzenesulfonamide hydrochloride; (3S)-1-Chloro-3-tosylamido-7-amino-2-heptanone hydrochloride. Grades: ≥98%. CAS No. 4272-74-6. Molecular formula: C14H21ClN2O3S·HCl. Mole weight: 369.3. | |
Z-Ala-Pro-Phe-chloromethylketone Quick inquiry Where to buy Suppliers range | Z-Ala-Pro-Phe-chloromethylketone is an inhibitor of the Ca2+- regulated nuclear scaffold proteinase (CRNSP). Synonyms: Z-APF-CMK; N-benzyloxycarbonyl-Ala-Pro-Phe-chloromethyl ketone. Grades: >98%. CAS No. 217658-18-9. Molecular formula: C26H30ClN3O5. Mole weight: 499.99. | |
Z-Phe-DL-Ala-FMK Quick inquiry Where to buy Suppliers range | Z-FA-FMK is an irreversible cysteine protease inhibitor, and it also inhibits caspases-2, -3, -6, and -7. Z-FA-FMK suppresses the degradation of fibrillar collagen by fibroblasts and osteoclasts, and reduces LPS-induced cytokine production via inhibition of NF-kappaB-dependent gene expression in macrophages. Uses: Cysteine proteinase inhibitors. Synonyms: Z-Phe-DL-Ala-fluoromethylketone; Zfa-fmk; benzyloxycarbonyl-Phe-Ala-fluormethylketone; benzyloxycarbonylphenylalanyl-alanine fluoromethyl ketone; Carbamic acid, N-((1S)-2-((3-fluoro-1-methyl-2-oxopropyl)amino)-2-oxo-1-(phenylmethyl)ethyl)-, phenylmethyl ester. Grades: ≥95%. CAS No. 197855-65-5. Molecular formula: C21H23FN2O4. Mole weight: 386.42. |