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A zinc enzyme isolated from pig kidney and cattle lens; activated by heavy metal ions. Type example of peptidase family M17. Group: Enzymes. Synonyms: leucine aminopeptidase; leucyl peptidase; peptidase S; cytosol aminopeptidase; cathepsin III; L-leucine aminopeptidase; leucinaminopeptidase; leucinamide aminopeptidase; FTBL proteins; proteinates FTBL; aminopeptidase II; aminopeptidase III; aminopeptidase I. Enzyme Commission Number: EC 3.4.11.1. CAS No. 9001-61-0. LAP. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4007; leucyl aminopeptidase; EC 3.4.11.1; 9001-61-0; leucine aminopeptidase; leucyl peptidase; peptidase S; cytosol aminopeptidase; cathepsin III; L-leucine aminopeptidase; leucinaminopeptidase; leucinamide aminopeptidase; FTBL proteins; proteinates FTBL; aminopeptidase II; aminopeptidase III; aminopeptidase I. Cat No: EXWM-4007.
Native Porcine Leucine Aminopeptidase
Leucine aminopeptidase (LAP) is a proteolytic enzyme which hydrolyzes the peptide bond adjacent to a free amino group. It is called leucine aminopeptidase because it rapidly catalyzes the hydrolysis of leucine containing peptides. However, it also catalyzes the hydrolytic release of other amino acids located at the N-terminal end of various peptides and proteins. The enzyme from porcine kidney has been extensively studied. It has a molecular weight of 255,000 and it consists of four subunits each having one atom of zinc. Group: Enzymes. Synonyms: Leucine Aminopeptidase; 9054-63-1; leucyl peptidase; peptidase S; cytosol aminopeptidase; cathepsin III; L-leucine aminopeptidase; leucinaminopeptidase; leucinamide aminopeptidase; FTBL proteins; proteinates FTBL; aminopeptidase II; aminopeptidase III; aminopeptidas. Enzyme Commission Number: EC 3.4.11.1. Purity: 90% (biuret). LAP. Activity: >100 U/mg protein. Storage: Stable when stored at 4°C. Do not freeze. Form: Ammonium Sulfate. Source: Porcine Kidney. Species: Porcine. Leucine Aminopeptidase; 9054-63-1; leucyl peptidase; peptidase S; cytosol aminopeptidase; cathepsin III; L-leucine aminopeptidase; leucinaminopeptidase; leucinamide aminopeptidase; FTBL proteins; proteinates FTBL; aminopeptidase II; aminopeptidase III; aminopeptidase I; EC 3.4.11.1; leucyl aminopeptidase; LAP. Cat No: NATE-1879.
Native Porcine Leucine Aminopeptidase, microsomal
Leucyl aminopeptidases are enzymes that preferentially catalyze the hydrolysis of leucine residues at the N-terminus of peptides and proteins. Other N-terminal residues can also be cleaved, however. LAPs have been found across superkingdoms. Identified LAPs include human LAP, bovine lens LAP, porcine LAP, Escherichia coli (E. coli) LAP (also known as PepA or XerB), and the solanaceous-specific acidic LAP (LAP-A) in tomato (Solanum lycopersicum). Group: Enzymes. Synonyms: Leucine Aminopeptidase, microsomal; 9054-63-1; leucine aminopeptidase; leucyl peptidase; peptidase S; cytosol aminopeptidase; cathepsin III; L-leucine aminopeptidase; leucinaminopeptidase; leucinamide aminopeptidase; FTBL prot. Enzyme Commission Number: EC 3.4.11.1. CAS No. 9054-63-1. LAP. Activity: Type VI-S, > 12 units/mg protein (biuret); Type IV-S, 10-40 units/mg protein (Bradford). Form: Type VI-S, lyophilized powder; Type IV-S, ammonium sulfate suspension. Source: Porcine kidney. Species: Porcine. Leucine Aminopeptidase, microsomal; 9054-63-1; leucine aminopeptidase; leucyl peptidase; peptidase S; cytosol aminopeptidase; cathepsin III; L-leucine aminopeptidase; leucinaminopeptidase; leucinamide aminopeptidase; FTBL proteins; proteinates FTBL; aminopeptidase II; aminopeptidase III; aminopeptidase I; EC 3.4.11.1; leucyl aminopeptidase; LAP. Cat No: NATE-0378.
10% β carotenolds powder(With soy protein)
It is a free-flowing reddish orange low dust powder with a slight gas. Product ID: PE-0657. Category: Colorant Excipients. Product Keywords: Colorant Excipients; 10% β carotenolds powder(With soy protein); PE-0657; Colorant Excipients;. Grade: Food Grade. Solubility: It can be dispersed into yellow suspension in cold water. Storage: room temp. Applications: As a colorant for tablets, syrups and emulsions.
10-DEBC hydrochloride
10-DEBC hydrochloride is a selective and reversible Akt/PKB inhibitor suppressing the IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5 μM), and inhibiting downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein. 10-DEBC hydrochloride inhibits cell growth (IC50 ~ 2-6 μM) and leads to apoptosis in rhabdomyosarcoma cells. Synonyms: 10H-Phenoxazine-10-butanamine, 2-chloro-N,N-diethyl-, hydrochloride (1:1); Akt Inhibitor X; 2-Chloro-N,N-diethyl-10H-phenoxazine-10-butanamine hydrochloride; 10-[4'-(N,N-Diethylamino)butyl]-2-chlorophenoxazine hydrochloride; 4-(2-chloro-10H-phenoxazin-10-yl)-N,N-diethylbutan-1-amine hydrochloride. Grades: ≥99% by HPLC. CAS No. 925681-41-0. Molecular formula: C20H25N2OCl.HCl. Mole weight: 381.34.
10-DEBC hydrochloride
Selective inhibitor of Akt/PKB. Inhibits IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5uM), suppressing downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein. Shows no activity at PDK1, SGK1 or PI 3-kinase. Inhibits cell growth (IC50 ~ 2-6uM) and induces apoptosis in rhabdomyosarcoma cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 925681-41-0. Pack Sizes: 10mg, 50mg. Molecular Formula: C20H25N2OCl.HCl, Method for Determining. US Biological Life Sciences.
Worldwide
10-deoxymethynolide desosaminyltransferase
DesVII is the glycosyltransferase responsible for the attachment of dTDP-D-desosamine to 10-deoxymethynolide or narbonolide during the biosynthesis of methymycin, neomethymycin, narbomycin, and pikromycin in the bacterium Streptomyces venezuelae. Activity requires an additional protein partner, DesVIII. Group: Enzymes. Synonyms: glycosyltransferase DesVII; DesVII. Enzyme Commission Number: EC 2.4.1.277. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2509; 10-deoxymethynolide desosaminyltransferase; EC 2.4.1.277; glycosyltransferase DesVII; DesVII. Cat No: EXWM-2509.
10-deoxymethynolide synthase
The product, 10-deoxymethynolide, contains a 12-membered ring and is an intermediate in the biosynthesis of methymycin in the bacterium Streptomyces venezuelae. The enzyme also produces narbonolide (see EC 2.3.1.240, narbonolide synthase). The enzyme has 29 active sites arranged in four polypeptides (pikAI - pikAIV) with a loading domain, six extension modules and a terminal thioesterase domain. Each extension module contains a ketosynthase (KS), keto reductase (KR), an acyltransferase (AT) and an acyl-carrier protein (ACP). Not all active sites are used in the biosynthesis. Group: Enzymes. Synonyms: pikromycin PKS. Enzyme Commission Number: EC 2.3.1.239. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2187; 10-deoxymethynolide synthase; EC 2.3.1.239; pikromycin PKS. Cat No: EXWM-2187.
10'-Desmethoxystreptonigrin
It is a close analogue of streptonigrin produced by selected streptomyces species. It is a moderately potent inhibitor of farnesylation of RAS P21 protein, 3-fold more active than streptonigrin. It has potent and broad spectrum antibacterial and antitumour activity. Synonyms: 2-Pyridinecarboxylic acid, 5-amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxo-2-quinolinyl)-4-(2-hydroxy-3-methoxyphenyl)-3-methyl-; 10-Desmethoxystreptonigrin. Grades: >95% by HPLC. CAS No. 136803-89-9. Molecular formula: C24H20N4O7. Mole weight: 476.44.
10Z-Hymenialdisine
Insecticidal and cytotoxic. Potent NF-kappaB inhibitor. Inhibits various pro-inflammatory cytokines such as IL-1, IL-2, IL-6, IL-8, TNF-alpha and nitric oxide (NO) in a variety of cell lines. ATP-competitive kinase inhibitor. Inhibits DNA damage checkpoint at G2, cyclin-dependent kinases CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclin E, CDK4/cyclin D1, CDK5/p25, GSK-3beta and casein kinase 1 (CK1). Potent mitogen-activated protein kinase kinase-1 (MEK-1) inhibitor. MARK (microtubule affinity-regulating kinase) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 82005-12-7. Pack Sizes: 500ug, 1mg. Molecular Formula: C??H??BrN?O?, Method for Determining. US Biological Life Sciences.
Isolated from sponge Axinella carteri. A potent inhibitor of mitogen-activated protein kinase kinase-1 (MEK-1) (IC50=6nm). Blocks the in vivo phosphorylation of the microtubule-binding protein tau at sites that are hyperphosphorylated by glycogen synthase kinase-b (GSK-3b) and CDK5/p35 in Alzheimers disease. Inhibitor of DNA damage checkpoint at G2 phase (IC50=6uM), cyclin-dependent kinases CDK1/cyclin B (IC50=22nm), CDK2/cyclin A (IC50=70 nm), CDK2/cyclin E (IC50=40nm), CDK4/cyclin D1 (IC50 = 600nm), CDK5/p25 (IC50=28nm), GSK-3b (IC50=10nm), and casein kinase 1 (CK1) (IC50=35nm). Group: Biochemicals. Grades: Highly Purified. CAS No. 82005-12-7. Pack Sizes: 250ug, 1mg. US Biological Life Sciences.
Worldwide
1,10-Phenanthroline monohydrate, 99%
1,10-Phenanthroline monohydrate, 99%. Uses: When complexed with copper, it possesses nuclease activity that has been used to study dna-protein interactions. Group: Ligands for functional metal complexes. Alternative Names: ZX-AT006983; SCHEMBL3790396; KSC269G7H; UNII-KSX215X00E; 1,10-phenanthroline-hydrate; TL8003406; 1,10-Phenanthroline hydrate; AX8021147; 1,10-Phenanthroline monohydrate, ACS reagent, 99%; TR-018323. CAS No. 5144-89-8. Product ID: 1,10-phenanthroline; hydrate. Molecular formula: 198.225g/mol. Mole weight: C12H10N2O. C1=CC2=C(C3=C(C=CC=N3)C=C2)N=C1.O. InChI=1S/C12H8N2. H2O/c1-3-9-5-6-10-4-2-8-14-12 (10)11 (9)13-7-1; /h1-8H; 1H2. PPQJCISYYXZCAE-UHFFFAOYSA-N.
1,1,1,3,3,3-Hexafluoro-2-propanol
1,1,1,3,3,3-Hexafluoro-2-propanol effects the native state of proteins, denaturing them as well as stabilizing the α-helical conformation of unfolded proteins and polypeptides. Group: Biochemicals. Alternative Names: 1,1,1,3,3,3-Hexafluoro-2-hydroxypropane; 1,1,1,3,3,3-Hexafluoroisopropanol; 1,1,1,3,3,3-Hexafluoroisopropyl Alcohol; 1,1,1,3,3,3-Hexafluoropropanol; 2, 2, 2-Trifluoro-1- (trifluoromethyl) ethanol; Bis (trifluoromethyl) methanol; HFIP; Hexafluoroisopropanol; Hexafluoroisopropyl Alcohol; NSC 96336. Grades: Highly Purified. CAS No. 920-66-1. Pack Sizes: 10g. US Biological Life Sciences.
Worldwide
1,1,1,3,3,3-Hexafluoro-2-propanol-d2
1,1,1,3,3,3-Hexafluoro-2-propanol-d2 is a labelled analogue of 1,1,1,3,3,3-Hexafluoro-2-propanol (H293880), it affects the native state of proteins, denaturing them as well as stabilizing the α-helical conformation of unfolded proteins and polypeptides. Group: Biochemicals. Grades: Highly Purified. CAS No. 38701-74-5. Pack Sizes: 250mg, 500mg. Molecular Formula: C3D2F6O. US Biological Life Sciences.
1,1,1-Trifluoro-methanesulfonic Acid 3-[[ (1, 1-Dimethylethoxy) carbonyl]amino]-1-cyclohexen-1-yl Ester is an intermediate in synthesizing tert-Butyl (3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-en-1-yl)carbamate (T302650), which is a reactant in the preparation of furo[3,2-c]pyridine derivatives as protein kinase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 1803033-60-4. Pack Sizes: 25mg, 50mg. Molecular Formula: C12H18F3NO5S. US Biological Life Sciences.
1,1,1-Trifluoro-methanesulfonic Acid 5-[[ (1, 1-Dimethylethoxy) carbonyl]amino]-1-cyclohexen-1-yl Ester is an intermediate in synthesizing tert-Butyl (3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-en-1-yl)carbamate (T302650), which is a reactant in the preparation of furo[3,2-c]pyridine derivatives as protein kinase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 1803033-59-1. Pack Sizes: 25mg, 50mg. Molecular Formula: C12H18F3NO5S. US Biological Life Sciences.
1, 1, 1-Trifluoromethane sulfonic Acid (E) -4-[1-[4-[2- (Dimethylamino) ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenyl Ester is an impurity of Tamoxifen (T006000), a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1370699-80-1. Pack Sizes: 5mg, 25mg. Molecular Formula: C27H28F3NO4S. US Biological Life Sciences.
1,1,2-Ethanetricarboxylic Acid 1,1,2-Triethyl Ester is a useful synthetic intermediate. It can be used to prepare Isobutylsuccinic Acid (I780660) which was used to synthesize succinimide derivatives as inhibitors of human leukocyte elastase, cathepsin G and proteinase 3. Group: Biochemicals. Grades: Highly Purified. CAS No. 7459-46-3. Pack Sizes: 5g, 10g. Molecular Formula: C11H18O6. US Biological Life Sciences.
1,1'-(2S,2'S)-2,2'-(5,5'-([1,1'-Biphenyl]-4,4'-diyl)bis[1H-imidazole-5,2-diyl))bis(pyrrolidine-2,1-diyl))diethanone is derived from 5,5'-[1,1'-Biphenyl]-4,4'-diylbis[2-(2S)-2-pyrrolidinyl-1H-imidazole] Hydrochloride (B397775), which is the derivative of Daclatasvir (D101500) that inhibits the HCV protein NS5A, and thus can be used a drug candidate for the treatment of hepatitis C (HCV). Group: Biochemicals. Grades: Highly Purified. CAS No. 1447744-93-5. Pack Sizes: 10mg, 25mg. Molecular Formula: C30H32N6O2, Molecular Weight: 508.61. US Biological Life Sciences.
(11 β)-11,21-Bis(1-ethoxyethoxy)-17-hydroxy-pregn-4-ene-3,20-dione is an impurity in the synthesis of Hydrocortisone-2,2,4,6,6,21,21-d7 (H714617), which is a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg, 250mg. Molecular Formula: C29H46O7. US Biological Life Sciences.
(11 β)-21-(1-Ethoxyethoxy)-11,17-dihydroxy-pregn-4-ene-3,20-dione is an intermediate in the synthesis of Hydrocortisone-2,2,4,6,6,21,21-d7 (H714617), which is a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg, 250mg. Molecular Formula: C25H38O6. US Biological Life Sciences.
(11 β)-21-(1-Ethoxyethoxy)-11,17-dihydroxy-pregn-4-ene-3,20-dione-d7 is an intermediate in the synthesis of Hydrocortisone-2,2,4,6,6,21,21-d7 (H714617), which is a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C25H31D7O6. US Biological Life Sciences.
Worldwide
11-cis-retinol dehydrogenase
This enzyme, abundant in the retinal pigment epithelium, catalyses the reduction of 11-cis-retinol to 11-cis-retinal while the substrate is bound to the retinal-binding protein. This is a crucial step in the regeneration of 11-cis-retinal, the chromophore of rhodopsin. The enzyme can also accept other cis forms of retinol. Group: Enzymes. Synonyms: RDH5 (gene name). Enzyme Commission Number: EC 1.1.1.315. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0227; 11-cis-retinol dehydrogenase; EC 1.1.1.315; RDH5 (gene name). Cat No: EXWM-0227.
1,1-Dioxide-5-(4-bromophenyl)-1,2,5-thiadiazolidin-3-one isused in the preparation of phenyl thiadiazolidinones as inhibitors of protein tyrosine phosphatase 1B (PTP1B) for treatment of diabetes mellitus. Group: Biochemicals. Grades: Highly Purified. CAS No. 692765-79-0. Pack Sizes: 10mg, 100mg. Molecular Formula: C8H7BrN2O3S, Molecular Weight: 291.12. US Biological Life Sciences.
Worldwide
11-oxo-β-amyrin 30-oxidase
A heme-thiolate protein (cytochrome P-450). The enzyme is involved in the biosynthesis of the triterpenoid saponin glycyrrhizin in the plant Glycyrrhiza uralensis (licorice). The enzyme from the plant Medicago truncatula can also hydroxylate β-amyrin. Group: Enzymes. Synonyms: CYP72A; CYP72A154. Enzyme Commission Number: EC 1.14.13.173. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0771; 11-oxo-β-amyrin 30-oxidase; EC 1.14.13.173; CYP72A; CYP72A154. Cat No: EXWM-0771.
[1(1S)]-2,3:4,5-Di-O-cyclohexylidene-6-O-(phenylmethyl)-D-myo-Inositol 4, 7, 7-trimethyl-3-oxo-2-oxabicyclo[2. 2. 1]heptane-1-carboxylate is an intermediate in the synthesis of phosphonate derivatives of myo-inositol for use in biochemical studies of inositol-binding proteins. Group: Biochemicals. Grades: Highly Purified. CAS No. 108340-80-3. Pack Sizes: 25mg, 250mg. Molecular Formula: C35H46O9, Molecular Weight: 610.73. US Biological Life Sciences.
[1(1S)]-2,3:4,5-Di-O-cyclohexylidene-6-O-(phenylmethyl)-D-myo-Inositol 4,7,7-trimethyl-3-oxo-2-oxabicyclo heptane-1-carboxylate is an intermediate in the synthesis of phosphonate derivatives of myo-inositol for use in biochemical studies of inositol-binding proteins. Synonyms: 2-Oxabicyclo[2.2.1]heptane, D-myo-inositol deriv.; Dispiro[cyclohexane-1,2'-benzo[1,2-d:3,4-d']bis[1,3]dioxole-7',1''-cyclohexane], D-myo-inositol deriv. CAS No. 108340-80-3. Molecular formula: C35H46O9. Mole weight: 610.73.
[1(1S)]-2,3-O-Cyclohexylidene-6-O-(phenylmethyl)-D-myo-inositol 1-(4, 7, 7-Trimethyl-3-oxo-2-oxabicyclo[2. 2. 1]heptane-1-carboxylate) is an intermediate in the synthesis of phosphonate derivatives of myo-inositol for use in biochemical studies of inositol-binding proteins. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C29H38O9, Molecular Weight: 530.61. US Biological Life Sciences.
[1(1S)]-2,3-O-Cyclohexylidene-6-O-(phenylmethyl)-D-myo-inositol 1-(4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carboxylate) is an intermediate in the synthesis of phosphonate derivatives of myo-inositol for use in biochemical studies of inositol-binding proteins. Molecular formula: C29H38O9. Mole weight: 530.61.
12-[[ (1, 1-Dimethylethyl) dimethylsilyl]oxy]-3, 15-dihydroxy-cholest-5-en-26-oic Acid is an intermediate in the synthesis of (25R)-3 β, 7α, 12α-Trihydroxy-5-cholestenoic Acid (T795130), which is an oxysterol, an oxidized derivatives of cholesterol (C432501), which may be important in many biological processes, including cholesterol homeostasis, atherosclerosis, sphingolipid metabolism, platelet aggregation, apoptosis, and protein prenylation,[1] though their roles are poorly understood. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C33H58O5Si. US Biological Life Sciences.
Penta-O-acetyl-5-thio-b-D-galactopyranoside, a chemical compound, may be employed as a substance to gauge enzyme function, with a particular preference for esterases, nucleases, and glycosidases. Additionally, the compound's effectiveness extends to protein purification.
1,2,3,4,6-Penta-O-pivaloyl-a-D-glucopyranoside
1,2,3,4,6-Penta-O-pivaloyl-a-D-glucopyranoside, a derivative of glucose with five pivalate groups, is an indispensable reagent for protein stabilization. Its diversified glycosylation, importantly, aids in the investigation of enzymatic characterizations. Remarkably, this compound could serve as a promising candidate in treating diabetes mellitus due to the potentiated hypoglycemic effect. Molecular formula: C31H52O11. Mole weight: 600.75.
HDAC6 Inhibitor is a potent and selective inhibitor of HDAC6 that poorly blocks other HDAC enzymes. HDAC6 is a predominantly cytoplasmic enzyme that targets α-tubulin, cortactin, and heat shock protein 90, as well as other substrates. Group: Biochemicals. Grades: Highly Purified. CAS No. 1259296-46-2. Pack Sizes: 500ug, 1mg. Molecular Formula: C16H17N3O3, Molecular Weight: 299.32. US Biological Life Sciences.
Worldwide
1,2,3,4-Tetra-O-benzoyl-D-glucuronic Acid
1,2,3,4-Tetra-O-benzoyl-D-glucuronic Acid is a precursor in the syntheses associated with agents that bear anticoagulative properties. Additionally, it proves essential in manufacturing lipid-protein blend targeting ailments specific to the cardiovascular spectrum. Synonyms: D-Galactose Tetraenzoate. Molecular formula: C34H26O11. Mole weight: 610.56.
1,2,3,4-Tetra-O-benzyl-6-O-triisopropylsilyl-b-D-galactopyranose, a complex carbohydrate compound, is extensively employed in synthetic drug development and drug candidate discovery. This elusive molecule aids in the production of glycan libraries and glycopeptides, facilitating the investigation of carbohydrate-protein interactions implicated in the pathogenesis of malignant neoplasms and viral infections. Molecular formula: C43H56O6Si. Mole weight: 697.01.
1-(2,3,5-Tri-O-benzoyl-2-C-b-methyl-b-D-ribofuranosyl)-5-nitropyridine-2(1H)-one, a multi-purpose compound frequently used in the biomedical milieu, serves as an inhibitor for various enzymes and proteins. Studies have shown that it presents remarkable efficiency against a variety of diseases. Synonyms: 1-(2,3,5-Tri-O-benzoyl-2-C-beta-methyl-beta-D-ribofuranosyl)-5-nitropyridine-2(1H)-one; 1-(2,3,5-Tri-O-benzoyl-2-C-β-methyl-β-D-ribofuranosyl)-5-nitropyridine-2(1H)-one. Grades: ≥95%. CAS No. 2072145-38-9. Molecular formula: C32H26N2O10. Mole weight: 598.56.
1,2,3,6-Tetra-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-D-mannopyranose is a complex carbohydrate compound. It is often used in biomedical research related to understanding carbohydrate-protein interactions, specifically pertaining to infectious diseases and potential antiviral drug development. CAS No. 20880-65-3. Molecular formula: C28H38O19. Mole weight: 678.59.
1,2,3,6-Tetra-O-benzoyl-b-D-mannopyranose
1,2,3,6-Tetra-O-benzoyl-b-D-mannopyranose is a carbohydrate moiety harnessed for glycoconjugate biosynthesis - molecules bearing carbohydrates linked covalently to proteins or lipids. Frequently utilized for the synthesis of glycopeptides and glycolipids, these play pivotal roles in the exploration of infectious ailments and neoplasms. The molecule's intricate structure confers a lasting impact on the formation and investigation of biologically relevant chemical compounds. CAS No. 171482-60-3. Molecular formula: C34H28O10. Mole weight: 596.58.
1,2,3-Tri-O-benzyl-b-D-galactopyranoside
1,2,3-Tri-O-benzyl-b-D-galactopyranoside is a chemical compound frequently used in studying glycosylation reactions in biomedical research. It is instrumental in developing anti-viral drugs where proper understanding of carbohydrate-protein interactions is crucial. Synonyms: 1,2,3-Tri-O-benzyl-b-D-galactopyranoside; 74801-06-2; BENZYL 2,3-DI-O-BENZYL-BETA-D-GALACTOPYRANOSIDE; (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-4,5,6-tris(phenylmethoxy)oxan-3-ol; Benzyl 2,3-Di-O-benzyl-?-D-galactopyranoside; Benzyl 2,3-Di-O-benzyl- beta -D-galactopyranoside; W-203713; Phenylmethyl 2,3-Bis-O-(phenylmethyl)-beta-D-galactopyranoside; (2R,3S,4S,5R,6R)-4,5,6-TRIS(BENZYLOXY)-2-(HYDROXYMETHYL)OXAN-3-OL. CAS No. 74801-06-2. Molecular formula: C27H30O6. Mole weight: 450.52.
1,2:4,5-Biscyclohexylidene L-myo-Inositol
Intermediate in the synthesis of phosphonate derivatives of myo-inositol for use in biochemical studies of inositol-binding proteins. Synonyms: 1,2:4,5-Di-O-cyclohexylidene-L-myo-inositol. Molecular formula: C18H28O6. Mole weight: 340.41.
1,2:4,5-di-O-Cyclohexylidene-D-myo-Inositol 3, 6-Bis(4, 7, 7-trimethyl-3-oxo-2-oxabicyclo[2. 2. 1]heptane-1-carboxylate) is an intermediate in the synthesis of phosphonate derivatives of myo-inositol for use in biochemical studies of inositol-binding proteins. Group: Biochemicals. Grades: Highly Purified. CAS No. 126647-65-2. Pack Sizes: 25mg, 250mg. Molecular Formula: C38H52O12, Molecular Weight: 700.81. US Biological Life Sciences.
1,2:4,5-di-O-Cyclohexylidene-D-myo-Inositol 3,6-Bis(4,7,7-trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carboxylate) is an intermediate in the synthesis of phosphonate derivatives of myo-inositol for use in biochemical studies of inositol-binding proteins. Synonyms: 1,2:4,5-di-O-Cyclohexylidene-D-myo-Inositol Bis[(1S,4R)-4,7,7-trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carboxylate] (9CI;2-Oxabicyclo[2.2.1]heptane, D-myo-inositol deriv.; Dispiro[cyclohexane-1,2'-benzo[1,2-d:4,5-d']bis[1,3]dioxole-6',1''-cyclohexane], D-myo-inositol deriv. CAS No. 126647-65-2. Molecular formula: C38H52O12. Mole weight: 700.81.
1,2-Bis(maleimido)ethane
1,2-Bis(maleimido)ethane (N,N'-Ethylenedimaleimide) is a protein cross-linking agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N,N'-Ethylenedimaleimide. CAS No. 5132-30-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W013538.
1, 2-Bis ( (pinacolato) boryl) ethane
An organoboronate derivative with inhibitory activity against Matrix metallo-proteinase (MMP-2). Group: Biochemicals. Alternative Names: 1,2-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)ethane; 2,2'-(1,2-Ethanediyl)bis[4,4,5,5-tetramethyl-1,3,2-Dioxaborolane. Grades: Highly Purified. CAS No. 364634-18-4. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
1, 2-Bis (trifluoromethyl) benzene
1, 2-Bis (trifluoromethyl) benzene is a useful reagent for preparing biphenyls through arylation of electron-deficient arenes with aryl halides. It was also employed to investigate the effect of aromatic trifluoromethylation, fluorination, and methylation on intermolecular n-n interactions. The results can provide insights on interactions between drug molecules and protein receptors. Group: Biochemicals. Grades: Highly Purified. CAS No. 433-95-4. Pack Sizes: 1g, 5g. Molecular Formula: C8H4F6, Molecular Weight: 214.11. US Biological Life Sciences.
Worldwide
1,2-Didecanoyl-sn-glycerol
1,2-Didecanoyl-sn-glycerol increases ornithine decarboxylase activity associated with tumor promotion in mouse skin. It can also function as a bioregulator of protein kinase C in human platelets. Group: Biochemicals. Grades: Highly Purified. CAS No. 60514-49-0. Pack Sizes: 10mg, 25mg. Molecular Formula: C23H44O5, Molecular Weight: 400.59. US Biological Life Sciences.
Worldwide
1,2-Dihexanoyl-sn-glycerol
1,2-Dihexanoyl-sn-glycerol functions as bioregulators of protein kinase C (PKC) in human platelets. Group: Biochemicals. Grades: Highly Purified. CAS No. 30403-47-5. Pack Sizes: 250mg, 500mg. Molecular Formula: C15H28O5, Molecular Weight: 288.38. US Biological Life Sciences.
Worldwide
1,2-Dimyristoyl-rac-glycerol
1,2-Dimyristoyl-rac-glycerol (C14:0) is a carboxylic acid ester, glycerolipid and diglyceride with an additional myristoyl group that facilitates interactions between proteins and lipids. Can be used as detergent or reagent. It plays a role in cell biology experiments involving the metabolism and metabolic pathways of glycerolipids. As a diglyceride, this substance consists of two fatty acid chains covalently bonded in the 1,2-form to a glycerol molecule. The diglyceride (DAG) study investigated the process by which DAG is depleted to inhibit fat accumulation. Reagent grade, for research use only. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 20255-94-1. Pack Sizes: 250 mg; 500 mg. Product ID: HY-W127409.
1,2-Dimyristoyl-sn-glycero-3-phosphocholine
1,2-Dimyristoyl-sn-glycero-3-phosphocholine is used in the generation of micelles and liposomes.1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a phospholipid found in eukaryotes, but not most bacteria. It is used in lipid bilayer studies to analyze organelle and cell membranes. Its also been used to study molecules in membranes, such as the interaction between DMPC and proteins in lab-constructed dimyristoyl phosphatidyl choline vesicles.CAS Number:18194-24-6. Group: Biochemicals. Alternative Names: 3,5,9-Trioxa-4-phosphatricosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxotetradecyl)oxy]-, hydroxide, inner salt, 4-oxide, (R)-; Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-dimyristin, L- (8CI); Choline, phosphate, ester with L-1,2-dimyristin(6CI); 1,2-Bis(myristoyl)-sn-glycerophosphocholine; 1,2-Dimyristoyl-3-sn-phosphatidylcholine; 1,2-Dimyristoyl-3-sn-phosphatidylcholine; 1,2-Dimyristoyl-L-3-phosphatidylcholine; 1,2-Dimyristoyl-L-phosphatidylcholine; 1,2-Dimyristoyl-L-a-phosphatidylcholine; 1,2-Dimyristoyl-sn-3-glycerophosphocholine; 1,2-Dimyristoyl-sn-glycero-3-phosphatidylcholine; 1,2-Dimyristoyl-sn-glycero-3-phosphocholine; 1,2-Dimyristoyl-sn-glycero-3-phosphocholine; 1,2-Dimyristoyl-sn-glycero-3-phosphorylcholine; 1,2-Dimyristoyl-sn-glycerol-3. Grades: Highly Purified. CAS No. 18194-24-6. Pack Sizes: 250mg, 500mg, 1g. US Biological Life Sciences.
Worldwide
1,2-Dioleoyl-sn-glycerol
1,2-Dioleoyl-sn-glycerol is an analog of the protein kinase C-activating second messenger DAG. Synonyms: Sn-1,2-Diolein; DG(18:1(9Z)/18:1(9Z)/0:0); 1,2-di-(9Z-octadecenoyl)-sn-glycerol; (S)-glyceryl 1,2-dioleate; DG(18:1/18:1/0:0). Grades: >99%. CAS No. 24529-88-2. Molecular formula: C39H72O5. Mole weight: 620.98.
1,2-Dioleoyl-sn-glycerol
ALN29882 is a glycerolipid located on the plasma membrane. It consists of two fatty acid chains covalently linked to a single glycerol molecule by means of an ester bond. 18:1 DG has been used as a source of diacylglycerol in the diacylglycerol O-acyltransferase 1 (DGAT1) assay. It is also used as a substrate in the DGAT-1 enzyme assay to evaluate compounds as potential inhibitors of DGAT-1. Suitable for lipoprotein overlay screening assays with the recombinant protein His-AtROP6. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: sn-1,2-Dioleoylglycerol. CAS No. 24529-88-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-141572.
PI(3)P diC16 is a synthetic and purified dipalmitoyl PI(3)P. PI(3)P is enriched in early endosomes having roles in endosome fusion and receptor sorting and internalization in multivesicular bodies. PI(3)P has also been found at the plasma membrane and is involved in the translocation of the glucose transport protein GLUT4. Synonyms: 1,2-dipalmitoyl-sn-glycero-3-phospho-(1'D-myo-inositol-3'-phosphate); PI(3)P diC16; L-alpha-Phosphatidyl-D-myo-inositol 3-monophosphate, dipalmitoyl; D-myo-Inositol, 1-(2R)-2,3-bis(1-oxohexadecyl)oxypropyl hydrogen phosphate 3-(dihydrogen phosphate); Phosphatidylinositol 3-phosphate diC16. Grades: >95%. CAS No. 165689-81-6. Molecular formula: C41H80O16P2. Mole weight: 891.01.
(±) -1, 2-Diphenyl-1-[2-[2- (dimethylamino) ethoxy]phenyl]butan-1-ol is an impurity of Tamoxifen (T006000); a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C26H31NO2, Molecular Weight: 389.53. US Biological Life Sciences.
(±) -1, 2-Diphenyl-1-[2-[2- (dimethylamino) ethoxy]phenyl]butan-1-ol-d5 is the isotope labelled analog of (±) -1, 2-Diphenyl-1-[2-[2- (dimethylamino) ethoxy]phenyl]butan-1-ol (D489855); an impurity of Tamoxifen (T006000) which is a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C26H26D5NO2, Molecular Weight: 394.56. US Biological Life Sciences.
(±) -1, 2-Diphenyl-1-[4-[2- (dimethylamino) ethoxy]phenyl]butan-1-ol is an impurity of Tamoxifen (T006000); a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Group: Biochemicals. Grades: Highly Purified. CAS No. 748-97-0. Pack Sizes: 10mg, 25mg. Molecular Formula: C26H31NO2, Molecular Weight: 389.53. US Biological Life Sciences.
(±) -1, 2-Diphenyl-1-[4-[2- (dimethylamino) ethoxy]phenyl]butan-1-ol-d5 is the isotope labelled analog of (±) -1, 2-Diphenyl-1-[4-[2- (dimethylamino) ethoxy]phenyl]butan-1-ol (D489850); an impurity of Tamoxifen (T006000) which is a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C26H26D5NO2, Molecular Weight: 394.56. US Biological Life Sciences.
Worldwide
1-(2-Ethoxy-2-oxoethyl)pyridin-1-ium-d5 Chloride
1-(2-Ethoxy-2-oxoethyl)pyridin-1-ium-d5 Chloride is an intermediate used in the synthesis of Girards Reagent P-d5 (G388502), which is a labeled girards reagent used in the identification and quantification of protein carbonylation as well as in the modification of nucleosides and nucleotides. Used in the preparation of potent photoactive agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 1853121-29-5. Pack Sizes: 25mg, 50mg. Molecular Formula: C9H7D5ClNO2, Molecular Weight: 206.68. US Biological Life Sciences.
Worldwide
12-Hydroxy-3-oxo-cholest-4-en-26-oic Acid
12-Hydroxy-3-oxo-cholest-4-en-26-oic Acid is an intermediate in the synthesis of (25R)-3 β, 7α, 12α-Trihydroxy-5-cholestenoic Acid (T795130), which is an oxysterol, an oxidized derivatives of cholesterol (C432501), which may be important in many biological processes, including cholesterol homeostasis, atherosclerosis, sphingolipid metabolism, platelet aggregation, apoptosis, and protein prenylation,[1] though their roles are poorly understood. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C27H40O4. US Biological Life Sciences.
1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(3,4,5-trimethoxyphenyl)-2-propen-1-one is a chalcone compound used as a selective inhibitor of breast cancer resistance protein. Group: Biochemicals. Grades: Highly Purified. CAS No. 53350-27-9. Pack Sizes: 25mg, 50mg. Molecular Formula: C20H22O7. US Biological Life Sciences.
1,2-O-Cyclohexylidene-4-O-(phenylmethyl)-D-myo-inositol is an intermediate in the synthesis of phosphonate derivatives of myo-inositol for use in biochemical studies of inositol-binding proteins. Group: Biochemicals. Grades: Highly Purified. CAS No. 116839-47-5. Pack Sizes: 10mg, 100mg. Molecular Formula: C19H26O6, Molecular Weight: 350.41. US Biological Life Sciences.
1,2-O-Cyclohexylidene-4-O-(phenylmethyl)-D-myo-inositol is an intermediate in the synthesis of phosphonate derivatives of myo-inositol for use in biochemical studies of inositol-binding proteins. Synonyms: Spiro[1,3-benzodioxole-2,1'-cyclohexane], D-myo-Inositol Deriv. CAS No. 116839-47-5. Molecular formula: C19H26O6. Mole weight: 350.41.
1,2-O-Isopropylidene-α-D-glucofuranose 3-tosylate
1,2-O-Isopropylidene-α-D-glucofuranose 3-tosylate is an intermediate in synthesizing 6R,7R,8aR-Glucosepane, one of the eight diastereomers of glucosepane. Glucosepane is a structurally complex protein posttranslational modification that is believed to exist in all living organisms. Research in humans suggests that glucosepane plays a critical role in the pathophysiology of both diabetes and human aging. Synonyms: α-D-1,2-O-Isopropylidene-glucofuranose 3-p-Toluenesulfonate; Furo[2,3-d]-1,3-dioxole α-D-Glucofuranose Derivative; 1,?2-O-(1-Methylethylidene)?-α-D-glucofuranose 3-(4-Methylbenzenesulfona?te); NSC 73271. CAS No. 2946-1-2. Molecular formula: C16H22O8S. Mole weight: 374.41.
1,2-Phenylene-bis-maleimide (1,2-PDM)
A short, sulfhydryl reactive hmombifunctional crosslinking reagent for protein crosslinking. Group: Biochemicals. Alternative Names: 1,2-PDM. Grades: Highly Purified. Pack Sizes: 5g. US Biological Life Sciences.
1-((2R,4aR,7R,8S,8aS)-8-Hydroxy-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-7-yl)pyrimidine-2,4(1H,3H)-dione is a promising therapeutic agent that is yet to gain approval from the FDA. This potential drug candidate has been reported to have beneficial effects in mitigating neurodegenerative disorders like Alzheimer's and Parkinson's disease through efficient amyloid beta and alpha-synuclein proteins aggregation inhibition. Synonyms: 2-(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)-1,5-anhydro-2-deoxy-4,6-O-[(R)-phenylmethylene]-D-altritol. CAS No. 401906-98-7. Molecular formula: C17H18N2O6. Mole weight: 346.33.
1-((2R,6S)-6-(Hydroxymethyl)morpholin-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione, a small molecule inhibitor, possesses remarkable potency against various cancer types. Its mechanism of action involves targeting proteins essential for cancer cell growth and replication, promoting tumor shrinkage and cell death. As demonstrated in lung, breast, colon, and ovarian cancer, it exhibits impressive antitumor activity, embodying a promising candidate for cancer therapy. Synonyms: Morpholino thymidine; 1-((2R,6S)-6-(hydroxymethyl)morpholin-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; 1-[(2R,6S)-6-(Hydroxymethyl)-2-morpholinyl]-5-methyl-2,4(1H,3H)-pyrimidinedione; YML1Y6H5HD; 1-[(2R,6S)-6-(hydroxymethyl)morpholin-2-yl]-5-methylpyrimidine-2,4-dione; 1-((2R,6S)-6-(Hydroxymethyl)-2-morpholinyl)-5-methyl-2,4(1H,3H)-pyrimidinedione; 1-(6-Hydroxymethyl-morpholin-2-yl)-5-methyl-1H-pyrimidine-2,4-dione; 2,4(1H,3H)-Pyrimidinedione, 1-((2R,6S)-6-(hydroxymethyl)-2-morpholinyl)-5-methyl-; UNII-YML1Y6H5HD; SCHEMBL24420143; CS-0100784; A897935. CAS No. 179073-10-0. Molecular formula: C10H15N3O4. Mole weight: 241.24.
12(S)-HETE
12(S)-HETE is the 12-lipoxygenase metabolite of arachidonic acid and has a mitogenic effect on cancer cell proliferation. 12(S)-HETE induces tyrosine phosphorylation of cellular proteins, promotes ERK and P38 MAPK phosphorylation, increases DNA synthesis, and stimulates the proliferation of pancreatic cancer cells [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 54397-83-0. Pack Sizes: 100 μg (312.04 μM * 1 mL in Ethanol). Product ID: HY-124404A.
12(S)-HpETE
12(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of platelet or leukocyte 12-lipoxygenase (12-LO) on arachidonic acid. It mediates the inhibitory synaptic response to FMRF-amide in Aplysia sensory neurons6 and inhibits Ca2+/calmodulin-dependent protein kinase II from rat brain cortex. Synonyms: 12-Hydroperoxyicosatetraenoate; (5Z,8Z,10E,12S,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoic acid. Grades: ≥98%. CAS No. 71774-10-2. Molecular formula: C20H32O4. Mole weight: 336.5.
1,3,4,6-Tetra-O-acetyl-2-deoxy-2-fluoro-D-glucopyranose, a laboratory-synthesized saccharide, has widespread employment in biochemistry and biomedical investigations. Integrating this sugar unit in the formation of diverse fluorinated carbohydrates endows scientists with the ability to analyze drug processing, establish protein-carbohydrate ties, and combat bacterial and viral infections efficiently. Synonyms: 2-Fluoro-2-deoxy-b-D-glucopyranose tetraacetate. CAS No. 31077-89-1. Molecular formula: C14H19FO9. Mole weight: 350.29.
1,3,4,6-Tetra-O-acetyl-2-deoxy-2-phthalimido-b-D-glucopyranoside, a synthetic compound, serves as a powerful chemical probe in scrutinizing protein and carbohydrate binding. Its versatility lies in its role as a glycoside and glycoconjugate precursor, as well as a substrate in carbohydrate metabolism. Synonyms: 2-Deoxy-2-N-phthalimido-1,3,4,6-tetra-O-acetyl-b-D-glucopyranose. CAS No. 10022-13-6. Molecular formula: C22H23NO11. Mole weight: 477.42.
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