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| Product | Description | |
|---|---|---|
| 3-Bromo-6-chloroimidazo[1,2-b]pyridazine | 3-Bromo-6-chloroimidazo[1,2-b]pyridazine. Group: Biochemicals. Grades: Highly Purified. CAS No. 13526-66-4. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C6H3BrClN3. US Biological Life Sciences. |  Worldwide |
| 3-Bromoimidazo[1,2-b]pyridazine | 3-Bromoimidazo[1,2-b]pyridazine. Group: Biochemicals. Grades: Highly Purified. CAS No. 18087-73-5. Pack Sizes: 100mg, 250mg. Molecular Formula: C6H4BrN3, Molecular Weight: 198.02. US Biological Life Sciences. | Worldwide |
| 3-Bromo-pyridazine hydrobromide | 3-Bromo-pyridazine hydrobromide. Group: Biochemicals. Grades: Highly Purified. CAS No. 215451-50-6. Pack Sizes: 100mg, 250mg. Molecular Formula: C4H3BrN2 HBr, Molecular Weight: 158.9848091. US Biological Life Sciences. | Worldwide |
| 6-Bromoimidazo[1,2-b]pyridazine | Heterocyclic Organic Compound. Alternative Names: 6-BROMOIMIDAZO[1,2-B]PYRIDAZINE, 1159977-65-7, CTK8C4347, MolPort-019-796-061, ANW-71616, AKOS015949260, PB16486, RP08687, AK-77314, KB-248042, FT-0684852, IMIDAZO[1,2-B]PYRIDAZINE, 6-BROMO-, C-8539. CAS No. 1159977-65-7. Molecular formula: C6H4BrN3. Mole weight: 198.023. Purity: 0.96. IUPACName: 6-bromoimidazo[1,2-b]pyridazine. Canonical SMILES: C1=CC(=NN2C1=NC=C2)Br. Catalog: ACM1159977657. |  |
| 6-Bromo-imidazo[1,2-b]pyridazine-2-carboxylic acid ethyl ester | Heterocyclic Organic Compound. Alternative Names: Ethyl 6-bromoimidazo[1,2-b]pyridazine-2-carboxylate, 1187236-98-1, CTK8C4116, ANW-71076, AKOS016008167, PB21447, AK104700, KB-253803, 6-BROMO-IMIDAZO[1,2-B]PYRIDAZINE-2-CARBOXYLIC ACID ETHYL ESTER. CAS No. 1187236-98-1. Molecular formula: C9H8BrN3O2. Mole weight: 270.082720 [g/mol]. Purity: 0.96. IUPACName: ethyl 6-bromoimidazo[1,2-b]pyridazine-2-carboxylate. Canonical SMILES: CCOC(=O)C1=CN2C(=N1)C=CC(=N2)Br. Catalog: ACM1187236981. | |
| 2-Bromo-2'-methoxyacetophenone | 2-Bromo-2'-methoxyacetophenone is used as a reagent in the synthesis of 3-biphenylimidazo[1,2-a]pyridines or [1,2-b]pyridazines and its analogs as novel Flaviviridae inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 31949-21-0. Pack Sizes: 1g, 5 g. Molecular Formula: C9H9BrO2, Molecular Weight: 229.07. US Biological Life Sciences. | Worldwide |
| 2-Bromo-1-(6-chloro-3-pyridazinyl)-Ethanone | 2-Bromo-1-(6-chloro-3-pyridazinyl)-Ethanone is used to prepare amide derivatives as β3 adrenergic receptor agonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 359794-51-7. Pack Sizes: 10mg, 100mg. Molecular Formula: C6H4BrClN2O, Molecular Weight: 235.47. US Biological Life Sciences. | Worldwide |
| 2-Bromoethylcyclopropane | 2-Bromoethylcyclopropane is used as a reagent to synthesize 22-Hydroxycholesterol (H918010) derivatives, compounds that act as serum cholesterol lowering agents. 2-Bromoethylcyclopropane is also used to prepare pyridazinones, compounds that act as cyclooxygenase 2-inhibitors (they possess anti-inflammatory and antiangiogenic effects). Group: Biochemicals. Grades: Highly Purified. CAS No. 36982-56-6. Pack Sizes: 50mg, 100mg. Molecular Formula: C5H9Br. US Biological Life Sciences. | Worldwide |
| 2-Cyclopropylethanol | 2-Cyclopropylethanol is used as a reagent to synthesize 22-Hydroxycholesterol (H918010) derivatives, compounds that act as serum cholesterol lowering agents. 2-Bromoethylcyclopropane is also used to prepare pyridazinones, 2-Cyclopropylethanol is also used to synthesize potent 15-Hydroxyprostaglandin dehydrogenase inhibitors, which ultimately minimize excessive scarring of wounds. Group: Biochemicals. Grades: Highly Purified. CAS No. 2566-44-1. Pack Sizes: 2.5g, 5g. Molecular Formula: C5H10O, Molecular Weight: 86.13. US Biological Life Sciences. | Worldwide |
| 4-(3-Bromoimidazo[1,2-b]pyridazin-6-yl)morpholine | Heterocyclic Organic Compound. Alternative Names: 4-(3-Bromoimidazo[1,2-b]pyridazin-6-yl)morpholine, 1012343-72-4, 4-{3-bromoimidazo[1,2-b]pyridazin-6-yl}morpholine, SureCN1055595, CTK3J9622, MolPort-019-918-566, ANW-51355, AKOS015835775, AG-L-20074, AK-26860, BR-26860, KB-237836, X8551. CAS No. 1012343-72-4. Molecular formula: C10H11BrN4O. Mole weight: 283.124540 [g/mol]. Purity: 0.96. IUPACName: 4-(3-bromoimidazo[1,2-b]pyridazin-6-yl)morpholine. Canonical SMILES: C1COCCN1C2=NN3C(=NC=C3Br)C=C2. Catalog: ACM1012343724. | |
| 6-Bromo-2-methyl-3(2H)-pyridazinone | Heterocyclic Organic Compound. Alternative Names: 6-Bromo-2-methyl-3(2H)-pyridazinone, 1123169-25-4, Ambcb4029510, AGN-PC-000GCE, 6-bromo-2-methylpyridazin-3-one, MolPort-016-631-214, ZINC29865944, AKOS006345072, 6-Bromo-2-methylpyridazin-3(2H)-one, AK121039, KB-247781, BB 0263050. CAS No. 1123169-25-4. Molecular formula: C5H5BrN2O. Mole weight: 189.010000 [g/mol]. Purity: 0.96. IUPACName: 6-bromo-2-methylpyridazin-3-one. Canonical SMILES: CN1C(=O)C=CC(=N1)Br. Catalog: ACM1123169254. | |
| ACBI1 | ACBI1 is a potent PROTAC degrader of BAF ATPase subunits SMARCA2 and SMARCA4, also degrades the polybromo-associated BAF (PBAF) complex member PBRM1, with DC50s of 6 nM, 11 nM and 32 nM for SMARCA2, SMARCA4 and PBRM1 in MV-4-11 cells, respectively. ACBI1 is composed of a bromodomain ligand, a linker, and the E3 ubiquitin ligase VHL. ACBI1 can induce anti-proliferative effects and apoptosis. Synonyms: ACBI 1; ACBI-1; (2S,4R)-N-(2-(2-(4-((4-(3-amino-6-(2-hydroxyphenyl)pyridazin-4-yl)piperazin-1-yl)methyl)phenoxy)ethoxy)-4-(4-methylthiazol-5-yl)benzyl)-1-((S)-2-(1-fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide. CAS No. 2375564-55-7. Molecular formula: C49H58FN9O7S. Mole weight: 936.12. |  |
| AZD 5153 | AZD5153 is a potent, selective, and orally available inhibitor of the bromodomain and extraterminal (BET) Inhibitor. It can simultaneously bind two bromodomains in BRD4 with the IC50 value of 5 nM, which has been shown to increase antitumor activity in multiple xenograft models of acute myeloid leukemia, multiple myeloma, and diffuse large B cell lymphoma. AZD5153 also shows enhanced potency as a result of bivalent binding and a clear correlation between BRD4 activity and cellular potency. Synonyms: (3R)-4-[2-[4-[1-(3-methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-4-piperidinyl]phenoxy]ethyl]-1,3-dimethyl-2-piperazinone; (3R)-4-[2-[4-[1-(3-methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl]phenoxy]ethyl]-1,3-dimethylpiperazin-2-one. Grades: ≥ 95 %. CAS No. 1869912-39-9. Molecular formula: C25H33N7O3. Mole weight: 479.57. | |
| AZD5153 6-Hydroxy-2-naphthoic acid | AZD5153 6-Hydroxy-2-naphthoic acid, a 6-hydroxy-2-naphthoic acid salt of AZD-5153, is a potent, selective, and orally available BET/BRD4 bromodomain inhibitor possessing a bivalent binding mode (pKi = 8.3 for BRD4). Synonyms: AZD5153 6-Hydroxy-2-naphthoic acid; AZD 5153 6-Hydroxy-2-naphthoic acid; AZD-5153 6-Hydroxy-2-naphthoic acid; 6-hydroxynaphthalene-2-carboxylic acid;4-[2-[4-[1-(3-methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl]phenoxy]ethyl]-1,3-dimethylpiperazin-2-one. CAS No. 1869912-40-2. Molecular formula: C36H41N7O6. Mole weight: 667.75. | |
| Bromosporine | Bromosporine, a broad spectrum inhibitor for bromodomains which play a key role in many cellular processes, is a chemical probe for bromodomain functional assays so that it is very helpful in elucidating further biological roles of reader domains. IC50: B. Synonyms: ethyl N-[6-[3-(methanesulfonamido)-4-methylphenyl]-3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-8-yl]carbamate Bromosporine 1619994-69-2 ethyl (3-methyl-6-(4-methyl-3-(methylsulfonamido)phenyl)-[1,2,4]triazolo[4,3-b]pyridazin-8-yl)carbamate Bromorsporine GTPL. CAS No. 1619994-69-2. Molecular formula: C17H20N6O4S. Mole weight: 404.44. | |
| GSK4027 | GSK4027 is a potent and selective inhibitor of p300/CBP-associated factor (PCAF)/general control nonderepressible 5 (GCN5) bromodomain (Ki = 1.4 nM; IC50 = 60 nM in a chromatin engagement assay). Synonyms: 4-bromo-2-methyl-5-[[(3R,5R)-1-methyl-5-phenyl-3-piperidinyl]amino]-3(2H)-pyridazinone. Grades: ≥95%. CAS No. 2079896-25-4. Molecular formula: C17H21BrN4O. Mole weight: 377.3. | |
| Parogrelil | Parogrelil is a selective and potent PDE III (PDE3) inhibitor with bronchodilating and anti-inflammatory activities. Synonyms: 5-bromo-3-[3-(4-chlorophenyl)propoxy]-4-(pyridin-3-ylmethylamino)-1H-pyridazin-6-one. Grades: 99%. CAS No. 139145-27-0. Molecular formula: C19H18BrClN4O2. Mole weight: 449.73. | |
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