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Quinolinicacid. Group: Biochemicals. Grades: Purified. CAS No. 89-00-9. Pack Sizes: 1g. US Biological Life Sciences.
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Quinolinicacid
Quinolinicacid is an endogenous N-methyl-D-aspartate ( NMDA ) receptor agonist synthesized from L-tryptophan via the kynurenine pathway and thereby has the potential of mediating N-methyl-D-aspartate neuronal damage and dysfunction [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 89-00-9. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 10 g. Product ID: HY-100807.
100g Pack Size. Group: Building Blocks, Organics, Pyridines. Formula: C7H5NO4. CAS No. 89-00-9. Prepack ID 70631764-100g. Molecular Weight 167.12. See USA prepack pricing.
Quinolinicacid inhibits glucose synthesis and is a metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinicacid are correlated with the severity of neuropsychological deficits in patients who have AIDS. Group: Biochemicals. Alternative Names: QuinolinicAcid; Pyridine-2,3-dicarboxylic Acid; Pyridin-2,3-dicarbonsaeure. Grades: Highly Purified. CAS No. 89-00-9. Pack Sizes: 10g. US Biological Life Sciences.
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2,3-Pyridinedicarboxylic acid
2,3-Pyridinedicarboxylic acid. Group: Biochemicals. Alternative Names: Quinolinicacid; Pyridine-2,3-dicarboxylic acid; Pyridin-2,3-dicarbonsaeure. Grades: Highly Purified. CAS No. 89-00-9. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C7H5NO4. US Biological Life Sciences.
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2,3-Pyridinedicarboxylic acid
Quinolinicacid is an endogenous NMDA agonist and transmitter candidate. It may distinguish between NMDA receptor subtypes. By overactivating NMDA receptors, quinolinicacid produces neurotoxicity, which has been implicated in certain neurodegenerative disorders. Uses: A metabolite of tryptophan; used to make assert (herbicide) and nicotinic acid. Synonyms: pyridine-2,3-dicarboxylic acid. Grades: 99 %. CAS No. 89-00-9. Molecular formula: C7H5NO4. Mole weight: 167.12.
2,3-Pyridinedicarboxylic acid-d3
A labeled NMDA receptor agonist. Inhibits glucose synthesis. Has potent neurotoxic effects. May be involved in many psychiatric disorders. Increased levels in the brain may contribute to apoptosis of astrocytes and neurons. Group: 2h labeled compounds. Alternative Names: QuinolinicAcid-d3. CAS No. 138946-42-6. Molecular formula: C7H2D3NO4. Mole weight: 170.14. Catalog: ACM138946426-1.
2-Amino-6-chloronicotinic Acid
2-Amino-6-chloronicotinic Acid is a useful synthetic intermediate. It is used in the synthesis of thiamine antagonist transketolase inhibitors. It is also used to prepare 2-aminonicotinic acid 1-oxides as inhibitors of quinolinicacid synthesis in the mammalian brain. Group: Biochemicals. Grades: Highly Purified. CAS No. 58584-92-2. Pack Sizes: 1g, 2.5g. Molecular Formula: C6H5ClN2O2, Molecular Weight: 172.57. US Biological Life Sciences.
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β-Nicotinic Acid Mononucleotide
A nucleotide of nicotinic acid which is produced from quinolinicacid by quinolinate phosphoribosyl transferase via transfer of a phosphoribose group. It is an intermediate of nicotinic acid adenine dinucleotide (NaAD) which is then converted to NAD via amidation and in turn converted to NADPH. Group: Biochemicals. Alternative Names: 3-Carboxy-1-(5-O-phosphono- β -D-ribofuranosyl) pyridinium Inner Salt; 3-Carboxy-1- β -D-ribofuranosyl pyridinium Hydroxide 5'-Phosphate Inner Salt; Nicotinate Mononucleotide; Nicotinate Ribonucleotide; Nicotinic Acid Ribonucleotide; Nicotinic Acid Ribotide; Nicotinic Mononucleotide; β-NaMN. Grades: Highly Purified. CAS No. 321-02-8. Pack Sizes: 1mg, 5mg, 10mg. US Biological Life Sciences.
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β-Nicotinic Acid Mononucleotide
A nucleotide of nicotinic acid which is produced from quinolinicacid by quinolinate phosphoribosyltransferase via transfer of a phosphoribose group. It is an intermediate of nicotinic acid adenine dinucleotide (NaAD) which is then converted to NAD via amidation and in turn converted to NADPH. Synonyms: 3-Carboxy-1-(5-O-phosphono-β-D-ribofuranosyl)pyridinium Inner Salt; 3-Carboxy-1-β-D-ribofuranosylpyridinium Hydroxide 5'-Phosphate Inner Salt; Nicotinate Mononucleotide; Nicotinate Ribonucleotide; Nicotinic Acid Ribonucleotide; Nicotinic Acid Ribotide; Nicotinic Mononucleotide; β-NaMN. Grades: 95%. CAS No. 321-02-8. Molecular formula: C11H14NO9P. Mole weight: 335.2.
The reaction is catalysed in the opposite direction. Since quinolinate is synthesized from L-tryptophan in eukaryotes, but from L-aspartate in some prokaryotes, this is the first NAD+ biosynthesis enzyme shared by both eukaryotes and prokaryotes. Group: Enzymes. Synonyms: quinolinate phosphoribosyltransferase (decarboxylating); quinolinicacid phosphoribosyltransferase; QAPRTase; NAD+ pyrophosphorylase; nicotinate mononucleotide pyrophosphorylase (carboxylating); quinolinic phosphoribosyltransferase. Enzyme Commission Number: EC 2.4.2.19. CAS No. 37277-74-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2646; nicotinate-nucleotide diphosphorylase (carboxylating); EC 2.4.2.19; 37277-74-0; quinolinate phosphoribosyltransferase (decarboxylating); quinolinicacid phosphoribosyltransferase; QAPRTase; NAD+ pyrophosphorylase; nicotinate mononucleotide pyrophosphorylase (carboxylating); quinolinic phosphoribosyltransferase. Cat No: EXWM-2646.
Tetrahydrobiopterin (THB) dihydrochloride
Tetrahydrobiopterin (THB) dihydrochloride is an activating Nitric Oxide Synthase (NOS)cofactor used in a variety of applications. The compound is also a known cofactor for the monooxygenases that hydroxylates phenylalanine, tyrosine, and tryptophan. Synthesis of THB has been documented to be the rate limiting step in the metabolism of phenylalanine and the biosynthesis of neurotransmiter amines. In mice, Quinolinicacid (sc-203226) induced convulsions were potentiated with Tetrahydrobiopterin dihydrochloride demonstrating that endogenous NO may be involved in stimulating the NMDA receptors. When hypertensive mice were fed THB, but were not introduced to hydralazine or tetrahydroneopterin, they displayed improved cardiac THB stores, phosphorylated phospholamban levels, and diastolic dysfunction. The compound has also been observed as an essential cofactor in the hydroxylation process in mammalian brains. Applications: An activating nos cofactor. Group: Coenzymes. Synonyms: (6R)-5,6,7,8-Tetrahydro-L-biopterin dihydrochloride. CAS No. 69056-38-8. Purity: ≥98%. Mole weight: 314.17. Appearance: Powder. Form: Solid. (6R)-5,6,7,8-Tetrahydro-L-biopterin dihydrochloride; Tetrahydrobiopterin (THB) dihydrochloride; 69056-38-8. Cat No: COEC-024.
10'-Desmethoxystreptonigrin
It is a close analogue of streptonigrin produced by selected streptomyces species. It is a moderately potent inhibitor of farnesylation of RAS P21 protein, 3-fold more active than streptonigrin. It has potent and broad spectrum antibacterial and antitumour activity. Synonyms: 2-Pyridinecarboxylic acid, 5-amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxo-2-quinolinyl)-4-(2-hydroxy-3-methoxyphenyl)-3-methyl-; 10-Desmethoxystreptonigrin. Grades: >95% by HPLC. CAS No. 136803-89-9. Molecular formula: C24H20N4O7. Mole weight: 476.44.
1-(1,1-Dimethylethyl)-6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid-d9 is labelled 1-(1,1-Dimethylethyl)-6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid (D473265) which is an antibacterial agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C14H3D9F3NO3, Molecular Weight: 308.3. US Biological Life Sciences.
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11-Desethyl Irinotecan
11-Desethyl Irinotecan is an impurity of the DNA topoisomerase inhibitor Irinotecan (I767500). Group: Biochemicals. Alternative Names: (4S)-4-Ethyl-3, 4, 12, 14-tetrahydro-4-hydroxy-3, 14-dioxo-1H-pyrano[3', 4':6, 7]indolizino[1, 2-b]quinolin-9-yl Ester [1,4'-Bipiperidine]-1'-carboxylic Acid; 1H-Pyrano[3', 4':6, 7]indolizino[1, 2-b]quinoline, [1,4'-Bipiperidine]-1'-carboxylic Acid deriv.; 10- [4- (1-Piperidino) -1-piperidinocarbonyloxy] camptothecin. Grades: Highly Purified. CAS No. 103816-16-6. Pack Sizes: 1mg. US Biological Life Sciences.
1- [ [ [ (1R) -1- [3- [ (2S, R) -2- [ [ (1-Carboxycyclopropyl) methyl] thio] -2- (7-chloro-2-quinolinyl) ethyl] phenyl] -3- [2- (1-hydroxy-1-methylethyl) phenyl] propyl] thio] methylcyclopropaneacetic Acid is an impurity of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Molecular formula: C41H46ClNO5S2. Mole weight: 732.39.
1,2,3,4-Tetrahydro-2-oxo-3-quinolineacetic Acid Methyl Ester is used in the synthesis of 1H-2,3,3a,4-tetrahydro-2-oxopyrrolo[2,3-b]quinolines which possess hypotensive properties with up to 34% decrease in aortic blood pressure after 30 minutes when administered to rats. It is also used as a reagent in the preparation of bicyclic compounds and compositions as PDF inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 61164-72-5. Pack Sizes: 100mg, 1g. Molecular Formula: C12H13NO3, Molecular Weight: 219.24. US Biological Life Sciences.
1-(2,3,8,8-Tetramethyl-1,2,3,4,5,6,7,8-octahydronaphthalen-2-yl)ethanone is a volatile and highly flammable liquid that has a low boiling point, making it an ideal candidate for use in lab experiments. This compound has a distinct chemical structure that is composed of an eight-membered ring of carbon atoms and an ethanone group. Uses: 1-(2,3,8,8-tetramethyl-1,2,3,4,5,6,7,8-octahydronaphthalen-2-yl)ethanone has been studied for its potential application in a variety of scientific research areas. it has been used as a reagent in the synthesis of various compounds, such as pyrrolidines, quinolines, and pyridines. it has also been used as a solvent in the extraction of various natural products, including essential oils, fatty acids. Group: Heterocyclic organic compound. Alternative Names: 7-ACETYL, 1,2,3,4,5,6,7,8-OCTAHYDRO-1,1,6,7-TETRAMETHYL NAPHTHALENE;2-ACETONAPHTHONE-1,2,3,4,5,6,7,8-OCTAHYDRO-2,3,8,8-TETRAMETHYL;1-(2,3,8,8-TETRAMETHYL-1,2,3,4,5,6,7,8-OCTAHYDRO-NAPHTHALEN-2-YL)-ETHANONE;ISOCYCLEMONE E;ISO E;ISO E SUPER;1-(1, 2, 3, 4, 5, 6, 7, 8a-octahydro-2, 3, 8, 8-tetramethyl-2-naphthalenyl)-Ethanone;1-(1, 2, 3, 4, 5, 6, 7, 8-octahydro-2, 3, 8, 8-tetramethyl-2-naphthalenyl)-e. CAS No. 54464-57-2. Molecular formula: C16H26O. Mole weight: 234.377. Appearance: Liquid. IUPACName: 1-(2,3,8,8-tetramethyl-1,3,4,5,6,7-hexahydronaphthalen-2-yl)ethanone. Canonical SMILES:
1-(2,4-Difluorophenyl)-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid is an intermediate used to prepare hydrazinoquinolones and azetidinylquinolinones derivatives as antibacterial agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 103995-01-3. Pack Sizes: 5mg, 50mg. Molecular Formula: C16H7F4NO3, Molecular Weight: 337.23. US Biological Life Sciences.
Intermediate in the synthesis of prolyl hydroxylase inhibitors. Group: Biochemicals. Alternative Names: Ethyl 1-(2-Cyclopropylethyl)-6-fluoro-4-hydroxy-2-oxo-1,2-dihydro-3-quinolinecarboxylate. Grades: Highly Purified. CAS No. 931399-20-1. Pack Sizes: 10mg. US Biological Life Sciences.
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1,?2-?Dihydro-?2-?oxo-4-?quinolinecarboxylic Acid
1,?2-?Dihydro-?2-?oxo-4-?quinolinecarboxylic Acid is a chemical constituent of vinegar Schisandra chinensis and is used as a indicator reagent in marking security documents. Group: Biochemicals. Grades: Highly Purified. CAS No. 15733-89-8. Pack Sizes: 5g, 10g. Molecular Formula: C10H7NO3, Molecular Weight: 189.17. US Biological Life Sciences.
1,4-Dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester has been studied as a novel influenza endonuclease inhibitor. They also function as high-affinity ligands at the benzodiazepine site of brain GABAA receptors. Group: Biochemicals. Alternative Names: 3-Ethoxycarbonyl-4(1H)-quinolone; 4-Oxo-1,4-dihydroquinoline-3-carboxylic acid ethyl ester; Ethyl 1,4-dihydro-4-oxoquinoline-3-carboxylate; Ethyl 4-oxo-1,4-dihydroquinoline-3-carboxylate. Grades: Highly Purified. CAS No. 52980-28-6. Pack Sizes: 5g. US Biological Life Sciences.
1-Bromo-4-(bromomethyl)-2,3-difluoro-benzene is used as a reactant for preparation of quinoline-4-carboxamides, spirocycles, and (pyrazolopyridinyl) aminomethylboronic acid derivatives useful in the treatment of viral infections. Group: Biochemicals. Grades: Highly Purified. CAS No. 162744-56-1. Pack Sizes: 100mg, 1g. Molecular Formula: C7H4Br2F2, Molecular Weight: 285.91. US Biological Life Sciences.
Intermediate in the preparation of Moxifloxacin derivatives. Group: Biochemicals. Alternative Names: 1-Cyclopropyl-1,4-dihydro-6,7,8-trifluoro-4-oxoquinoline-3-carboxylic Acid; 1-Cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid. Grades: Highly Purified. CAS No. 94695-52-0. Pack Sizes: 10mg. US Biological Life Sciences.
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1-Cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Anhydride with Diacetyl Borate
1-Cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Anhydride with Diacetyl Borate is an impurity of Gatifloxacin (G250000), an antibacterial agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
An intermediate in the preparation of Moxifloxacin derivatives. Synonyms: 1-Cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylicAcidEthylEster. CAS No. 94242-51-0. Molecular formula: C15H12F3NO3. Mole weight: 311.25.
Intermediate in the preparation of Moxifloxacin derivatives. Group: Biochemicals. Alternative Names: 1-Cyclopropyl-1,4-dihydro-6,7,8-trifluoro-4-oxoquinoline-3-carboxylic Acid Ethyl Ester; 1-Cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid Ethyl Ester. Grades: Highly Purified. CAS No. 94242-51-0. Pack Sizes: 25mg. US Biological Life Sciences.
1-Cyclopropyl-6,7-difluoro-1,4-dihydro-5-methyl-4-oxo-3-quinolinecarboxylic Acid-d4 is labelled 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-5-methyl-4-oxo-3-quinolinecarboxylic Acid (C989205) which is an antibacterial agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C14H7D4F2NO3, Molecular Weight: 283.26. US Biological Life Sciences.
An impurity of Moxifloxacin, a fourth-generation antibacterial drug. Synonyms: Moxifloxacin Impurity R. Grades: 99% by HPLC. CAS No. 452092-31-8. Molecular formula: C15H13F2NO4. Mole weight: 309.26.
1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid. Group: Biochemicals. Alternative Names: Moxifloxacin Q acid. Grades: Highly Purified. CAS No. 112811-72-0. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C14H11F2NO4. US Biological Life Sciences.
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1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic Acid Anhydride with Diacetyl Borate
1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic Acid Anhydride with Diacetyl Borate is an impurity of Gatifloxacin (G250000), an antibacterial agent. Group: Biochemicals. Alternative Names: 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic Acid Anhydride with Boric Acid. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
1-Cyclopropyl-7-(3,5-dimethyl-1-piperazinyl)-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid is an impurity of Sparfloxacin (S679250), a fluorinated quinolone antibacterial. Group: Biochemicals. Grades: Highly Purified. CAS No. 103460-90-8. Pack Sizes: 5mg, 10mg. Molecular Formula: C19H21F2N3O3, Molecular Weight: 377.39. US Biological Life Sciences.
Intermediate in the preparation of Moxifloxacin intermediates. Group: Biochemicals. Alternative Names: 1-Cyclopropyl-7,8-difluoro-1,4-dihydro-6-methoxy-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
1-Cyclopropyl-7-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid can be used to prepare iminoquinolinecarboxam ide s. It can also be used as a reagent to prepare 1-alkyl-1,4-dihydro-4-imino-3-quinolinecarboxylic acid derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 157372-99-1. Pack Sizes: 5mg, 50mg. Molecular Formula: C13H10FNO3, Molecular Weight: 247.22. US Biological Life Sciences.
1-Cyclopropyl-7-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid-d4 is labelled 1-Cyclopropyl-7-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid (C989220) which can be used to prepare iminoquinolinecarboxam ide s. 1-Cyclopropyl-7-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid (C989220) can also be used as a reagent to prepare 1-alkyl-1,4-dihydro-4-imino-3-quinolinecarboxylic acid derivatives. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C13H6D4FNO3, Molecular Weight: 251.25. US Biological Life Sciences.
1-Cyclopropyl-7-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic Acid can be used as a reactant to prepare 7-amino alkylidenyl-heterocyclic quinolones as antibacterial agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 221221-16-5. Pack Sizes: 1mg. Molecular Formula: C14H12FNO4, Molecular Weight: 277.25. US Biological Life Sciences.
1-Cyclopropyl-7-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic Acid-d4 is labelled 1-Cyclopropyl-7-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic Acid (C989225) which can be used as a reactant to prepare 7-amino alkylidenyl-heterocyclic quinolones as antibacterial agents. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C14H8D4FNO4, Molecular Weight: 281.27. US Biological Life Sciences.
1-Cyclopropyl-8-(difluoromethoxy)-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid is a fluoroquinolone derivative that shows antibacterial activity in vitro. Group: Biochemicals. Grades: Highly Purified. CAS No. 128426-95-9. Pack Sizes: 1mg, 10mg. Molecular Formula: C14H9F4NO4, Molecular Weight: 331.22. US Biological Life Sciences.