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| Product | Description | |
|---|---|---|
| Rapamycin | 100mg Pack Size. Group: Biochemicals, Organics, Research Organics & Inorganics. Formula: C51H79NO13. CAS No. 53123-88-9. Prepack ID 41676136-100mg. Molecular Weight 914.17. See USA prepack pricing. |  |
| Rapamycin | Rapamycin. Group: Molecular Biology. Grades: Highly Purified. CAS No. 53123-88-9. Pack Sizes: 25mg. Molecular Formula: C51H79NO13. US Biological Life Sciences. |  Worldwide |
| Rapamycin | Rapamycin Inhibitor. Uses: Scientific use. Product Category: T1537. CAS No. 53123-88-9. |  |
| Rapamycin | Rapamycin is an mTOR inhibitor immunosuppressant and kinase inhibitor with both antifungal and antineoplastic properties. It selectively inhibits the transcriptional activation of cytokines. Uses: Antifungal and antineoplastic agent. Synonyms: Sirolimus; (-)-Rapamycin; AY 22989; AY-22989; I-2190A; NSC 226080; RAPA; RAP; RPM; SLM; WY-090217; Everolimus EP Impurity A. Grades: >98%. CAS No. 53123-88-9. Molecular formula: C51H79NO13. Mole weight: 914.19. |  |
| Rapamycin | Rapamycin (Sirolimus; AY 22989) is a potent and specific mTOR inhibitor with an IC 50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1 [1]. Rapamycin is an autophagy activator, an immunosuppressant [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Sirolimus; AY-22989. CAS No. 53123-88-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g; 2 g; 5 g. Product ID: HY-10219. |  |
| Rapamycin | Rapamycin (Sirolimus; AY 22989) is a potent and specific mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine solution. Product Category: Inhibitors. Appearance: Powder. CAS No. 53123-88-9. Molecular formula: C51H79NO13. Mole weight: 914.18. Purity: 0.98. IUPACName: (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone. Canonical SMILES: C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)O)C)/C)O)OC)C)C)/C)OC. Density: 1.035 g/ml. Product ID: ACM53123889. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Rapamycin | Sirolimus; 23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine; (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4]-oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone. anti-cancer therapeutic. CAS No. 53123-88-9. Product ID: 8-04299. Molecular formula: C51H79NO13. Mole weight: 914.17. Purity: 0.98. Properties: white crystalline. |  |
| Rapamycin-13C,d3 (contains d0) Technical Grade | Labelled Rapamycin. A triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word for Easter Island, RapaÂNui. Used as an immunosuppressant; antirestenotic. Group: Biochemicals. Grades: Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: C5013CH76D3NO13, Molecular Weight: 918.18. US Biological Life Sciences. | Worldwide |
| Rapamycin-31,42-Diester Impurity | Rapamycin-31,42-Diester Impurity. Uses: For analytical and research use. Group: Impurity standards. Catalog: APS002921. Format: Neat. |  |
| Rapamycin-d3 | Rapamycin-d 3 is the deuterium labeled Rapamycin. Rapamycin is a potent and specific mTOR inhibitor with an IC 50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant [1] [2]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Sirolimus-d3; AY-22989-d3. CAS No. 392711-19-2. Pack Sizes: 500 μg; 1 mg. Product ID: HY-10219S. | |
| Rapamycin Dialdehyde | Rapamycin Dialdehyde is an impurity of Rapamycin (R124000), a triene macrolide antibiotic isolated from Streptomyces hygroscopicus and a useful immunosuppressant to prevent rejection in organ transplantation. Group: Biochemicals. Grades: Highly Purified. CAS No. 500733-49-3. Pack Sizes: 1mg, 5mg. Molecular Formula: C51H79NO15, Molecular Weight: 946.17. US Biological Life Sciences. | Worldwide |
| Rapamycin (Everolimus EP Impurity A) | Rapamycin (Everolimus EP Impurity A). Uses: For analytical and research use. Group: Impurity standards. CAS No. 53123-88-9. Molecular Formula: C51H79NO13. Mole Weight: 914.19. Catalog: APB53123889. | |
| Rapamycin Impurity 1 | An impurity of Rapamycin. Rapamycin is a macrolide compound. It inhibits activation of T cells and B cells by reducing the production of interleukin-2. Rapamycin can be used to coat coronary stents and prevent organ transplant rejection. Grades: > 95%. Molecular formula: C51H79NO13. Mole weight: 914.2. | |
| Rapamycin Impurity 1 | Rapamycin Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 141392-23-6. Molecular Formula: C50H77NO13. Mole Weight: 900.16. Catalog: APB141392236. | |
| Rapamycin Impurity 11 | Rapamycin Impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 159351-88-9. Molecular Formula: C52H81NO13. Mole Weight: 928.21. Catalog: APB159351889. | |
| Rapamycin Impurity 12 | Rapamycin Impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 156223-31-3. Molecular Formula: C50H77NO13. Mole Weight: 900.16. Catalog: APB156223313. | |
| Rapamycin Impurity 16 | Rapamycin Impurity 16. Uses: For analytical and research use. Group: Impurity standards. CAS No. 253431-35-5. Molecular Formula: C51H79NO13. Mole Weight: 914.19. Catalog: APB253431355. | |
| Rapamycin impurity 2 | Rapamycin impurity 2. CAS No. 1704711-11-5. Product ID: 8-05127. Molecular formula: C54H85NO14. Mole weight: 972.28. | |
| Rapamycin Impurity 2 | An impurity of Rapamycin. Rapamycin is a macrolide compound. It inhibits activation of T cells and B cells by reducing the production of interleukin-2. Rapamycin can be used to coat coronary stents and prevent organ transplant rejection. Grades: > 95%. Molecular formula: C50H77NO13. Mole weight: 900.17. | |
| Rapamycin Impurity 20 | Rapamycin Impurity 20. Uses: For analytical and research use. Group: Impurity standards. CAS No. 392711-19-2. Molecular Formula: C51H76D3NO13. Mole Weight: 917.21. Catalog: APB392711192. | |
| Rapamycin Impurity 23 | Rapamycin Impurity 23. Uses: For analytical and research use. Group: Impurity standards. CAS No. 147438-27-5. Molecular Formula: C51H79NO13. Mole Weight: 914.19. Catalog: APB147438275. | |
| Rapamycin Impurity 25 | Rapamycin Impurity 25. Uses: For analytical and research use. Group: Impurity standards. CAS No. 572924-54-0. Molecular Formula: C53H84NO14P. Mole Weight: 990.21. Catalog: APB572924540. | |
| Rapamycin Impurity 26 | Rapamycin Impurity 26. Uses: For analytical and research use. Group: Impurity standards. CAS No. 136293-03-3. Molecular Formula: C51H77NO13. Mole Weight: 912.17. Catalog: APB136293033. | |
| Rapamycin Impurity 27 | Rapamycin Impurity 27. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1473389-19-3. Molecular Formula: C49H75NO12. Mole Weight: 870.13. Catalog: APB1473389193. | |
| Rapamycin Impurity 28 | Rapamycin Impurity 28. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1062122-62-6. Molecular Formula: C53H84NO14P. Mole Weight: 990.22. Catalog: APB1062122626. | |
| Rapamycin Impurity 29 | Rapamycin Impurity 29. Uses: For analytical and research use. Group: Impurity standards. CAS No. 144293-63-0. Molecular Formula: C51H79NO13. Mole Weight: 914.19. Catalog: APB144293630. | |
| Rapamycin Impurity 3 | An impurity of Rapamycin. Rapamycin is a macrolide compound. It inhibits activation of T cells and B cells by reducing the production of interleukin-2. Rapamycin can be used to coat coronary stents and prevent organ transplant rejection. Grades: > 95%. CAS No. 157054-84-7. Molecular formula: C52H81NO13. Mole weight: 928.22. | |
| Rapamycin Impurity 30 | Rapamycin Impurity 30. Uses: For analytical and research use. Group: Impurity standards. CAS No. 144370-88-7. Molecular Formula: C51H79NO13. Mole Weight: 914.19. Catalog: APB144370887. | |
| Rapamycin Impurity 31 | Rapamycin Impurity 31. Uses: For analytical and research use. Group: Impurity standards. CAS No. 179076-04-1. Molecular Formula: C57H93NO13Si. Mole Weight: 1028.45. Catalog: APB179076041. | |
| Rapamycin Impurity 32 | Rapamycin Impurity 32. Uses: For analytical and research use. Group: Impurity standards. CAS No. 851536-75-9. Molecular Formula: C55H87NO14. Mole Weight: 986.29. Catalog: APB851536759. | |
| Rapamycin Impurity 33 | Rapamycin Impurity 33. Uses: For analytical and research use. Group: Impurity standards. CAS No. 143030-02-8. Molecular Formula: C57H93NO13Si. Mole Weight: 1028.45. Catalog: APB143030028. | |
| Rapamycin Impurity 34 | Rapamycin Impurity 34. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1062645-51-5. Molecular Formula: C58H95N2O17P. Mole Weight: 1123.37. Catalog: APB1062645515. | |
| Rapamycin Impurity 35 | Rapamycin Impurity 35. Uses: For analytical and research use. Group: Impurity standards. CAS No. 85537-35-5. Molecular Formula: C50H77NO12. Mole Weight: 884.16. Catalog: APB85537355. | |
| Rapamycin Impurity 36 | Rapamycin Impurity 36. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1290606-22-2. Molecular Formula: C52H81NO13. Mole Weight: 928.21. Catalog: APB1290606222. | |
| Rapamycin Impurity 37 | Rapamycin Impurity 37. Uses: For analytical and research use. Group: Impurity standards. CAS No. 221877-56-1. Molecular Formula: C52H79N5O12. Mole Weight: 966.23. Catalog: APB221877561. | |
| Rapamycin Impurity 4 | Rapamycin Impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 151519-50-5. Molecular Formula: C50H77NO13. Mole Weight: 900.16. Catalog: APB151519505. | |
| Rapamycin Impurity 48 | Rapamycin Impurity 48. Uses: For analytical and research use. Group: Impurity standards. CAS No. 151945-42-5. Molecular Formula: C51H79NO13. Mole Weight: 914.19. Catalog: APB151945425. | |
| Rapamycin Impurity 4 (Sirolimus-31,42-Diester Impurity) | An impurity of Rapamycin. Rapamycin is a macrolide compound. It inhibits activation of T cells and B cells by reducing the production of interleukin-2. Rapamycin can be used to coat coronary stents and prevent organ transplant rejection. Grades: > 95%. Molecular formula: C61H95NO19. Mole weight: 1146.43. | |
| Rapamycin Impurity 5 | Rapamycin Impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 142382-16-9. Molecular Formula: C50H77NO13. Mole Weight: 900.16. Catalog: APB142382169. | |
| Rapamycin Impurity 58 | Rapamycin Impurity 58. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1392400-31-5. Molecular Formula: C61H101NO14Si. Mole Weight: 1100.56. Catalog: APB1392400315. | |
| Rapamycin Impurity 6 | Rapamycin Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 500733-49-3. Molecular Formula: C51H79NO15. Mole Weight: 946.18. Catalog: APB500733493. | |
| Rapamycin Impurity 7 | Rapamycin Impurity 7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 83482-58-0. Molecular Formula: C50H77NO12. Mole Weight: 884.16. Catalog: APB83482580. | |
| Rapamycin, seco, Sodium Salt (FRAP, mTOR Inhibitor, Sirolimus) | A metabolite of Sirolimus. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Rapamycin (Sirolimus) | Cas No. 53123-88-9. | |
| (19E/Z)-seco-[4-O-[2-Hydroxy(ethyl)-d4]] Rapamycin Sodium Salt | A labelled metabolite of the immunosuppressant macrolide SDZ RAD (also known as Everolimus E945400) which is an analog of the parent drug Rapamycin (R124000). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C53H78D4NNaO14, Molecular Weight: 984.23. US Biological Life Sciences. | Worldwide |
| (19E/Z)-seco-[4-O-(2-Hydroxyethyl)] Rapamycin | (19E/Z)-seco-[4-O-(2-Hydroxyethyl)] Rapamycin is a metabolite of the immunosuppressant macrolide SDZ RAD (also known as Everolimus E945400) which is an analog of the parent drug Rapamycin (R124000). Group: Biochemicals. Grades: Highly Purified. CAS No. 1062122-63-7. Pack Sizes: 1mg, 5mg. Molecular Formula: C53H83NO14. US Biological Life Sciences. | Worldwide |
| (19E/Z)-seco-[4-O-(2-Hydroxyethyl)] Rapamycin Sodium Salt | Metabolite of the immunosuppressant macrolide SDZ RAD (also known as Everolimus E945400) which is an analog of the parent drug Rapamycin. Group: Biochemicals. Alternative Names: (2S)-1-[2-oxo-2-[(2R, 3R, 6S)-tetrahydro-2-hydroxy-6-[(2S, 3E, 5E, 7E, 9S, 11R, 13R, 14R, 15E, 17R, 19E/Z, 21R)-14-hydroxy-22-[(1S, 3R, 4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-2, 13-dimethoxy-3, 9, 11, 15, 17, 21-hexamethyl-12, 18-dioxo-3, 5, 7, 15, 19-docosapentaen-1-yl]-3-methyl-2H-pyran-2-yl]acetyl]-2-piperidinecarboxylic Acid Sodium Salt; seco Everolimus Sodium Salt. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| (19Z)-seco-[4-O-(2-hydroxyethyl)] rapamycin sodium salt | (19Z)-seco-[4-O-(2-hydroxyethyl)] rapamycin sodium salt. Group: Biochemicals. Alternative Names: (2S)-1-[2-oxo-2-[(2R, 3R, 6S)-tetrahydro-2-hydroxy-6-[(2S, 3E, 5E, 7E, 9S, 11R, 13R, 14R, 15E, 17R, 19Z, 21R)-14-hydroxy-22-[(1S, 3R, 4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-2, 13-dimethoxy-3, 9, 11, 15, 17, 21-hexamethyl-12, 18-dioxo-3, 5, 7, 15, 19-docosapentaen-1-yl]-3-methyl-2H-pyran-2-yl]acetyl]-2-piperidinecarboxylic acid sodium salt; seco everolimus sodium salt. Grades: Highly Purified. CAS No. 220127-31-1. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C53H82NNaO14. US Biological Life Sciences. | Worldwide |
| 27-O-Desmethyl Rapamycin (27-O-Desmethyl Sirolimus) | A metabolite of Rapamycin. Rapamycin is a macrolide compound. It inhibits activation of T cells and B cells by reducing the production of interleukin-2. Rapamycin can be used to coat coronary stents and prevent organ transplant rejection. Grades: > 95%. Molecular formula: C50H77NO13. Mole weight: 900.17. | |
| 28-epi-Rapamycin | An epimer of Rapamycin. Rapamycin is a macrolide compound. It inhibits activation of T cells and B cells by reducing the production of interleukin-2. Rapamycin can be used to coat coronary stents and prevent organ transplant rejection. Synonyms: 28-epi-Rapamycin; (31S)-Rapamycin. Grades: > 95%. CAS No. 253431-35-5. Molecular formula: C51H79NO13. Mole weight: 914.2. | |
| 28-Epirapamycin | 28-Epirapamycin is an epimer of Rapamycin (R124000), a triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word for Easter Island, RapaNui. Used as an immunosuppressant; antirestenotic. Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants. Group: Biochemicals. Grades: Highly Purified. CAS No. 253431-35-5. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C51H79NO13. US Biological Life Sciences. | Worldwide |
| 28-Ethyl-d4-hydroxy Rapamycin | 28-Ethyl-d4-hydroxy Rapamycin is the labeled analogue of 28-Ethylhydroxy Rapamycin (E678640), an impurity of Everolimus (E945400),a derivative of Rapamycin. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C53H79D4NO14, Molecular Weight: 962.25. US Biological Life Sciences. | Worldwide |
| 28-O-Methyl-rapamycin | 28-O-Methyl-rapamycin is a derivative of Rapamycin (R124000), a triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word for Easter Island, RapaNui. Used as an immunosuppressant; antirestenotic. Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants. Group: Biochemicals. Grades: Highly Purified. CAS No. 159351-88-9. Pack Sizes: 1mg. Molecular Formula: C52H81NO13. US Biological Life Sciences. | Worldwide |
| 42-O-[2-[[Hydroxy (2-bromoethoxy) phosphinyl]oxy]ethyl] Rapamycin | Rapamycin derivative. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 42-O- [2- [ [Hydroxy [2- (trimethylammonio) ethoxy] phosphinyl] oxy] ethyl] Rapamycin Inner Salt | A phosphocholine ester metabolite of the immunosuppressant macrolide SDZ RAD (also known as Everolimus E945400) which is an analog of the parent drug Rapamycin. Group: Biochemicals. Alternative Names: ATG 181. Grades: Highly Purified. CAS No. 1062645-51-5. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 42-O-tert-Butyldi methyl silyloxyethyl-d4 Rapamycin | Intermediate to make Everolimus-d4. Group: Biochemicals. Alternative Names: 42-O- [2- [ [ (1, 1-Dimethylethyl) dimethylsilyl] oxy] ethyl-d4] rapamycin; Everolimus-d4 tert-Butyldimethylsilyl Ether. Grades: Highly Purified. CAS No. 1356839-88-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 7-O-Demethyl rapamycin | 7-O-Demethyl rapamycin, a derivative of Rapamycin (HY-10219), has antifungal activity and immunosuppressant properties. 7-O-Demethyl rapamycin has useful tumor cell growth-inhibiting activity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 7-O-Demethyl Cypher; 7-O-Demethyl Rapammune; 7-O-Demethyl Sirolimus. Product Category: Inhibitors. Appearance: Solid. CAS No. 151519-50-5. Molecular formula: C50H77NO13. Mole weight: 900.15. Purity: 0.96. IUPACName: 7-O-Demethyl Rapamycin. Canonical SMILES: CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)O)C)C)O)OC)C)C)C)O. Product ID: ACM151519505. Alfa Chemistry ISO 9001:2015 Certified. Categories: Novolimus. | |
| 7-O-Demethyl Rapamycin | Rapamycin metabolite. Group: Biochemicals. Alternative Names: 7-O-Demethyl Cypher; 7-O-Demethyl Rapammune; 7-O-Demethyl Sirolimus. Grades: Highly Purified. CAS No. 151519-50-5. Pack Sizes: 1mg. Molecular Formula: C??H??NO??, Molecular Weight: 900.15. US Biological Life Sciences. | Worldwide |
| 7-O-Desmethyl Rapamycin | A metabolite of Rapamycin. Rapamycin is a macrolide compound. It inhibits activation of T cells and B cells by reducing the production of interleukin-2. Rapamycin can be used to coat coronary stents and prevent organ transplant rejection. Synonyms: 7-O-Demethyl Cypher; 7-O-Demethyl Rapammune; 7-O-Demethyl Sirolimus. Grades: > 95%. CAS No. 151519-50-5. Molecular formula: C50H77NO13. Mole weight: 900.17. | |
| Demethoxy Rapamycin | A derivative of Rapamycin. Rapamycin is a macrolide compound. It inhibits activation of T cells and B cells by reducing the production of interleukin-2. Rapamycin can be used to coat coronary stents and prevent organ transplant rejection. Synonyms: Demethoxyrapamycin; Rapamycin, 32-demethoxy-; Desmethoxyrapamycin; 83482-58-0; AY 24668; (16E, 24E, 26E, 28E)-1, 18-dihydroxy-12-[1-(4-hydroxy-3-methoxycyclohexyl)propan-2-yl]-30-methoxy-15, 17, 21, 23, 29, 35-hexamethyl-11, 36-dioxa-4-azatricyclo[30.3.1.04, 9]hexatriaconta-16, 24, 26, 28-tetraene-2, 3, 10, 14, 20-pentone; AY-24668; 19-O-Desmethoxy rapamycin. Grades: > 95%. CAS No. 83482-58-0. Molecular formula: C50H77NO12. Mole weight: 884.17. | |
| Seco Rapamycin (sodium salt) | Seco-rapamycin is the first in vivo open-ring metabolite of rapamycin which is a natural macrolide immunosuppressant. Seco-rapamycin inhibits the ChT-L (D) and PGPH (E) peptidases, and activate the T-L (F) peptidase and poorly activates mTOR. IC50: ChT-L. Uses: A decomposition product of rapamycin (r124000). Synonyms: sodium;(2S)-1-[2-[(2R,3R,6S)-2-hydroxy-6-[(2S,9S,11R,13R,14R,17R,21R)-14-hydroxy-22-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxodocosa-3,5,7,15,19-pentaenyl]-3-methyloxan-2-yl]-2-oxoacetyl]piperidine-2-c. Grades: > 95%. CAS No. 148554-65-8. Molecular formula: C51H78NNaO13. Mole weight: 936.15. | |
| Sirolimus (Rapamycin) | Sirolimus, also known as rapamycin, is a natural macrocyclic lactone produced by the bacterium Streptomyces hygroscopicus, with immunosuppressant properties. In cells, sirolimus binds to the immunophilin FK Binding Protein-12 (FKBP-12) to generate an immunosuppressive complex that binds to and inhibits the activation of the mammalian Target Of Rapamycin (mTOR), a key regulatory kinase. This results in inhibition of T lymphocyte activation and proliferation that occurs in response to antigenic and cytokine (IL-2, IL-4, and IL-15) stimulation and inhibition of antibody production. Uses: Designed for use in research and industrial production. Additional or Alternative Names: RAPA; RAP; RPM; SLM; AY 22989; AY22989; AY-22989; SILA 9268A; WY090217; WY-090217; WY 090217; C07909; D00753; sirolimus; rapamycin; Rapamune. Product Category: Others. Appearance: White to off-white solid powder. CAS No. 53123-88-9. Molecular formula: C51H79NO13. Mole weight: 914.17. Purity: >98%. IUPACName: (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34, 34a-hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4] oxaazacyclohentriacontine-1,5,11,28,29 (4H,6H,31H)-pentone. Canonical SMILES: C[C@@H](C([C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(C[C@@H]([C@H](C)C[C@@H]1CC[C@@H](O)C(OC)C1 | |
| SMER28 (Small-Molecule Enhancer of Rapamycin-28, 6-Bromo-4-allylaminoquinazoline) | Cell permeable. Acts as a positive regulator of autophagy, acting via mTOR-independent mechanism. SMER28 increases autophagosome synthesis and enhances the clearance of model autophagy substrates such as A53T a-synuclein and mutant huntingtin fragments. It is also protective in Drosophila model of Huntingtons Disease (HD). Group: Biochemicals. Grades: Highly Purified. CAS No. 307538-42-7. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| Temsirolimus (Rapamycin 42-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate, CCL-779) | Ester analog of rapamycin. Group: Biochemicals. Alternative Names: Rapamycin 42-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate; CCL-779. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Wortmannin-Rapamycin Conjugate | Wortmannin is a potent inhibitor of PI3K enzymes, and rapamycin blocks mTOR. The wortmannin-rapamycin conjugate inhibits the growth of HT-29 colon tumors and A498 renal tumors in mice better than rapamycin alone. Synonyms: Wortmannin-Rapamycin Conjugate; 1067892-47-0; AKOS040755180. Grades: ≥98%. CAS No. 1067892-47-0. Molecular formula: C88H131N3O23. Mole weight: 1598.9. | |
| 2-(4-((3-Amino-6-bromoquinolin-4-yl)amino)-phenyl)-2-methylpropanenitrile | 2-(4-((3-Amino-6-bromoquinolin-4-yl)amino)-phenyl)-2-methylpropanenitrile is used as a reagent in the preparation of imidazo quinoline derivatives, compounds that act as mammalian target of rapamycin (mTOR) an phosphatidylinositol 3-kinase (PI3K-kinase) inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 915019-52-2. Pack Sizes: 5mg, 10mg. Molecular Formula: C19H17BrN4. US Biological Life Sciences. | Worldwide |
| 2,4-Dichloro-5,7-dihydro-7,7-dimethylfuro[3,4-d]pyrimidine | 2,4-Dichloro-5,7-dihydro-7,7-dimethylfuro[3,4-d]pyrimidine is used for preparation and study of pharmacokinetics, and antitumor activity of dihydrofuro[3,4-d]pyrimidines as inhibitors of mammalian target of rapamycin kinase. Group: Biochemicals. Grades: Highly Purified. CAS No. 1260088-72-9. Pack Sizes: 25mg, 50mg. Molecular Formula: C8H8Cl2N2O, Molecular Weight: 219.07. US Biological Life Sciences. | Worldwide |
| 28-Ethylhydroxy Everolimus-d4 Impurity | 28-Ethylhydroxy Everolimus-d4 Impurity is a deuterium labelled 28-Ethylhydroxy-everolimus Impurity (E945435). It is also an impurity of Everolimus (E945400), which is a derivative of Rapamycin (R124000). Everolimus inhibits cytokine-mediated lymphocyte proliferation. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C55H83D4NO15, Molecular Weight: 1006.3. US Biological Life Sciences. | Worldwide |
| 28-Ethylhydroxy Everolimus Impurity | 28-Ethylhydroxy Everolimus Impurity is an impurity of Everolimus (E945400), which is a derivative of Rapamycin (R124000). Everolimus inhibits cytokine-mediated lymphocyte proliferation. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C55H87NO15, Molecular Weight: 1002.28. US Biological Life Sciences. | Worldwide |
| 2- ( (tert-Butyldimethylsilyl) oxy) ethyl 2,2,2-trichloroacetimidate | 2- ( (tert-Butyldimethylsilyl) oxy) ethyl 2,2,2-trichloroacetimidate is an intermediate in the synthesis of 28-Ethylhydroxy Rapamycin (E678640), which is an impurity of Everolimus (E945400),a derivative of Rapamycin. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250mg, 500mg. Molecular Formula: C10H20Cl3NO2Si. US Biological Life Sciences. | Worldwide |
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