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| Product | Description | |
|---|---|---|
| Spherical Refractory High-entropy Alloy (HEA) Powder (Cr-Fe-Co-Ni) | Spherical Refractory High-entropy Alloy (HEA) Powder (Cr-Fe-Co-Ni) has high strength, high hardness, good high-temperature performance, excellent wear resistance, and corrosion resistance, which can be used in 3D printing. Alfa Chemistry provides spherical Refractory High-entropy Alloy (HEA) Powder (Cr-Fe-Co-Ni) with high fluidity at a competitive price. Uses: Spherical heas powder has gained interest for its promising properties including enhanced irradiation resistance, high-temperature strength, and corrosion resistance. Group: High entropy alloys. Pack Sizes: Vacuum packaging, 1kg/bag, 2kg/bag; iron drum lined with plastic bag 25 kg/drum; special packaging is available according to user requirements. |  |
| Spherical Refractory High-entropy Alloy (HEA) Powder (Cr-Mn-Fe-Co-Ni) | High-entropy alloys are a new type of metal material composed of 4, 5, or more metal elements in nearly equal atomic ratios, also known as complex component alloys. As CrMnFeCoNi, which have high strength, high hardness, good high-temperature performance, excellent wear resistance, and corrosion resistance, which can be used in 3D printing. Uses: Spherical heas powder has gained interest for its promising properties including enhanced irradiation resistance, high-temperature strength, and corrosion resistance. Group: High entropy alloys. Pack Sizes: Vacuum packaging, 1kg/bag, 2kg/bag; iron drum lined with plastic bag 25 kg/drum; special packaging is available according to user requirements. | |
| Spherical Refractory High-entropy Alloy Powder (HEA, Al32.72Fe9.05Si7.24Mn) | Spherical Refractory High-entropy Alloy Powder (Al32.72Fe9.05Si7.24Mn) has high strength, high hardness, good high-temperature performance, excellent wear resistance, and corrosion resistance, which can be used in 3D printing. Alfa Chemistry supplies spherical Refractory High-entropy Alloy Powder (Al32.72Fe9.05Si7.24Mn) with high fluidity at a competitive price. Uses: Spherical heas powder has gained interest for its promising properties including enhanced irradiation resistance, high-temperature strength, and corrosion resistance. Group: High entropy alloys. Pack Sizes: Vacuum packaging, 1kg/bag, 2kg/bag; iron drum lined with plastic bag 25 kg/drum; special packaging is available according to user requirements. | |
| Spherical Refractory High-entropy Alloy Powder (HEA, AlCoCr2FeMo0.5Ni) | Spherical Refractory High-entropy Alloy Powder (AlCoCr2FeMo0.5Ni) has high strength, high hardness, good high-temperature performance, excellent wear resistance, and corrosion resistance, which can be used in 3D printing. Alfa Chemistry provides spherical Refractory High-entropy Alloy Powder (AlCoCr2FeMo0.5Ni) with high fluidity at a competitive price. Uses: Spherical heas powder has gained interest for its promising properties including enhanced irradiation resistance, high-temperature strength, and corrosion resistance. Group: High entropy alloys. Pack Sizes: Vacuum packaging, 1kg/bag, 2kg/bag; iron drum lined with plastic bag 25 kg/drum; special packaging is available according to user requirements. | |
| Spherical Refractory High-entropy Alloy Powder (HEA, Cu11.85Al3.2Mn0.1Ti) | Spherical Refractory High-entropy Alloy Powder (Cu11.85Al3.2Mn0.1Ti) has high strength, high hardness, good high-temperature performance, excellent wear resistance, and corrosion resistance, which can be used in 3D printing. Alfa Chemistry provides spherical Refractory High-entropy Alloy Powder (Cu11.85Al3.2Mn0.1Ti) with high fluidity at a competitive price. Uses: Spherical heas powder has gained interest for its promising properties including enhanced irradiation resistance, high-temperature strength, and corrosion resistance. Group: High entropy alloys. Pack Sizes: Vacuum packaging, 1kg/bag, 2kg/bag; iron drum lined with plastic bag 25 kg/drum; special packaging is available according to user requirements. | |
| Spherical Refractory High-entropy Alloy Powder (HEA, Fe50Mn30Co10Cr10) | Spherical Refractory High-entropy Alloy Powder (Fe50Mn30Co10Cr10) has high strength, high hardness, good high-temperature performance, excellent wear resistance, and corrosion resistance, which can be used in 3D printing. Alfa Chemistry provides spherical Refractory High-entropy Alloy Powder (Fe50Mn30Co10Cr10) with high fluidity at a competitive price. Uses: Spherical heas powder has gained interest for its promising properties including enhanced irradiation resistance, high-temperature strength, and corrosion resistance. Group: High entropy alloys. Pack Sizes: Vacuum packaging, 1kg/bag, 2kg/bag; iron drum lined with plastic bag 25 kg/drum; special packaging is available according to user requirements. | |
| Spherical Refractory High-entropy Alloy Powder (HEA, Fe-Co-Ni-Cr-Mn) | Spherical Refractory High-entropy Alloy Powder (HEA, Fe-Co-Ni-Cr-Mn) has high strength, high hardness, good high-temperature performance, excellent wear resistance, and corrosion resistance, which can be used in 3D printing. Alfa Chemistry provides spherical Refractory High-entropy Alloy Powder (Fe-Co-Ni-Cr-Mn) with high fluidity at a competitive price. Uses: Spherical heas powder has gained interest for its promising properties including enhanced irradiation resistance, high-temperature strength, and corrosion resistance. Group: High entropy alloys. Pack Sizes: Vacuum packaging, 1kg/bag, 2kg/bag; iron drum lined with plastic bag 25 kg/drum; special packaging is available according to user requirements. | |
| Spherical Refractory High-entropy Alloy Powder (HEA, V-Nb-Mo-Ta-W) | Alfa Chemistry supplies Spherical Refractory High-entropy Alloy Powder (HEA, V-Nb-Mo-Ta-W) with high fluidity at a competitive price. Uses: Spherical heas powder have gained interest for their promising properties including enhanced irradiation resistance, high-temperature strength, and corrosion resistance. Group: High entropy alloys. Pack Sizes: Vacuum packaging, 1kg/bag, 2kg/bag; iron drum lined with plastic bag 25 kg/drum; special packaging is available according to user requirements. | |
| 10-Methyl Docetaxel | 10-Methyl Docetaxel is a metabolite of Docetaxel (D494420), a microtubule inhibitor that has the potential to be used in treating hormone refractory prostate cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 160084-81-1. Pack Sizes: 5mg, 50mg. Molecular Formula: C44H55NO14, Molecular Weight: 821.91. US Biological Life Sciences. |  Worldwide |
| 1,3-bis((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-piperidin-1-yl)propan-1-one | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: 1-Propanone, 1,3-bis((3R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo(3,4-d)pyrimidin-1-yl)-1-piperidinyl)-; Ibrutinib impurity PDEJ. Grades: ≥95%. CAS No. 1987905-93-0. Molecular formula: C47H46N12O3. Mole weight: 826.97. |  |
| 1-[4-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: 2-Propen-1-one, 1-[4-[4-aMino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyriMidin-1-yl]-1-piperidinyl]-; Ibrutinib Impurity WZYG. Grades: ≥95%. CAS No. 936563-92-7. Molecular formula: C25H24N6O2. Mole weight: 440.50. | |
| 1-butyl-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: Ibrutinib Impurity IMDJ. Grades: ≥95%. CAS No. 2213398-77-5. Molecular formula: C21H21N5O. Mole weight: 359.43. | |
| 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-ethyl-3-(4-phenoxyphenyl)- | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: Ibrutinib Impurity IMYJ. Grades: ≥95%. CAS No. 2213398-76-4. Molecular formula: C19H17N5O. Mole weight: 331.37. | |
| 1-Methyl-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-methyl-3-(4-phenoxyphenyl)-; Ibrutinib impurity JBZ. Grades: ≥95%. CAS No. 2213398-75-3. Molecular formula: C18H15N5O. Mole weight: 317.34. | |
| 2,2-Difluoroethyl Triflate | 2,2-Difluoroethyl Triflate is used to prepare kinesin spindle protein inhibitors for treatment of taxane-refractory cancer. It is also used to synthesize MexAB-?OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Group: Biochemicals. Grades: Highly Purified. CAS No. 74427-22-8. Pack Sizes: 1g, 5g. Molecular Formula: C3H3F5O3S, Molecular Weight: 214.11. US Biological Life Sciences. | Worldwide |
| 2-?Fluoro-?N-?methyl-?4-?nitrobenzamide | 2-?Fluoro-?N-?methyl-?4-?nitrobenzamide is used in the preparation of androgen receptor antagonists MDV3100. MDV3100 is also a clinical candidate for the treatment of hormone refractory prostrate cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 915087-24-0. Pack Sizes: 50mg, 250mg. Molecular Formula: C8H7FN2O3, Molecular Weight: 198.15. US Biological Life Sciences. | Worldwide |
| (2R)-2-Amino-4-methyl-1-[(2R)-2-methyloxiran-2-yl]pentan-1-one Trifluoroacetate Salt | (2R)-2-Amino-4-methyl-1-(2-methyloxiran-2-yl)pentan-1-one Trifluoroacetate Salt s an impurity of carfilzomib (C183460). Carfilzomib is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C11H18F3NO4, Molecular Weight: 285.26. US Biological Life Sciences. | Worldwide |
| (2R,4S)-4-((t-Butoxycarbonyl)amino)-1,2-dihydroxy-2,6-dimethyl-3-oxohepan-4-tyl | (2R,4S)-4-((t-Butoxycarbonyl)amino)-1,2-dihydroxy-2,6-dimethyl-3-oxohepan-4-tyl is an intermediate used in the synthesis of Carfilzomib (2S,4S)-Diol (C183495), which is a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. Group: Biochemicals. Grades: Highly Purified. CAS No. 1541172-78-4. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C14H27NO5, Molecular Weight: 289.37. US Biological Life Sciences. | Worldwide |
| (2R,4S)-4-((t-Butoxycarbonyl)amino)-2-hydroxy-2,6-dimethyl-3-oxoheptyl Acetate | (2R,4S)-4-((t-Butoxycarbonyl)amino)-2-hydroxy-2,6-dimethyl-3-oxoheptyl Acetate is an intermediate in synthesizing Carfilzomib (2S,4S)-Diol (C183495), a derivative of Carflizomib (C183460), which is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C16H29NO6, Molecular Weight: 331.4. US Biological Life Sciences. | Worldwide |
| (2S)-2-Amino-4-methyl-1-[(2R)-2-methyloxiranyl]-1-pentanone Trifluoroacetate | (2S)-2-Amino-4-methyl-1-[(2R)-2-methyloxiranyl]-1-pentanone Trifluoroacetate is an intermediate of Carfilzomib (C183460) which is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. Group: Biochemicals. Grades: Highly Purified. CAS No. 247068-85-5. Pack Sizes: 1mg, 10mg. Molecular Formula: C11H18F3NO4, Molecular Weight: 285.26. US Biological Life Sciences. | Worldwide |
| (2S,4R)-4-((t-Butoxycarbonyl)amino)-1,2-dihydroxy-2,6-dimethyl-3-oxohepan-4-tyl | (2S,4R)-4-((t-Butoxycarbonyl)amino)-1,2-dihydroxy-2,6-dimethyl-3-oxohepan-4-tyl is an intermediate used in the synthesis of Carfilzomib (2S,4R)-Diol (C183500), is a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C14H27NO5, Molecular Weight: 289.37. US Biological Life Sciences. | Worldwide |
| (2S,4R)-4-((t-Butoxycarbonyl)amino)-2-hydroxy-2,6-dimethyl-3-oxoheptyl Acetate | (2S,4R)-4-((t-Butoxycarbonyl)amino)-2-hydroxy-2,6-dimethyl-3-oxoheptyl Acetate is an intermediate in synthesizing Carfilzomib (2S,4R)-Diol (C183500), a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C16H29NO6, Molecular Weight: 331.4. US Biological Life Sciences. | Worldwide |
| (2S,4R)-4-((t-Butoxycarbonyl)amino)-2-hydroxy-2,6-dimethyl-3-oxoheptyl Acetate Trifluoroacetate Salt | (2S,4R)-4-((t-Butoxycarbonyl)amino)-2-hydroxy-2,6-dimethyl-3-oxoheptyl Acetate Trifluoroacetate Salt is an intermediate in synthesizing Carfilzomib (2S,4R)-Diol (C183500), a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C11H21NO4; (C2HF3O2), Molecular Weight: 231.2911402. US Biological Life Sciences. | Worldwide |
| (2S,4S)-4-Amino-2-hydroxy-2,6-dimethyl-3-oxoheptyl Acetate TFA Salt | (2S,4S)-4-Amino-2-hydroxy-2,6-dimethyl-3-oxoheptyl Acetate TFA Salt is an intermediate used in the synthesis of Carfilzomib (2S,4S)-Diol (C183495), which is a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C11H21NO4; C2HF3O2, Molecular Weight: 231.2911402. US Biological Life Sciences. | Worldwide |
| (2S,4S)-4-((t-Butoxycarbonyl)amino)-2-hydroxy-2,6-dimethyl-3-oxoheptyl Acetate | (2S,4S)-4-((t-Butoxycarbonyl)amino)-2-hydroxy-2,6-dimethyl-3-oxoheptyl Acetate is an intermediate in synthesizing Carfilzomib (2S,4S)-Diol (C183495), a derivative of Carflizomib (C183460), which is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C16H29NO6, Molecular Weight: 331.4. US Biological Life Sciences. | Worldwide |
| 4-Deacetyl-4-propionyl Cabazitaxel | 4-Deacetyl-4-propionyl Cabazitaxel is an impurity of Cabazitaxel, which is a microtubule inhibitor for the treatment of hormone-refractory prostate cancer. Synonyms: (2α, 5β, 7β, 10β, 13α)-1-Hydroxy-13-{[(2R, 3S)-2-hydroxy-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-3-phenylpropanoyl]oxy}-7, 10-dimethoxy-9-oxo-4-(propionyloxy)-5, 20-epoxytax-11-en-2-yl benzoate; Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-12b-(1-oxopropoxy)-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-. Molecular formula: C46H59NO14. Mole weight: 849.96. | |
| (4S,5S)-3-tert-Butoxycarbonyl-2-(4-anisyl)-4-phenyl-5-oxazolidinecarboxylic Acid | (4S,5S)-3-tert-Butoxycarbonyl-2-(4-anisyl)-4-phenyl-5-oxazolidinecarboxylic Acid is an impurity of Cabazitaxel, which is a microtubule inhibitor for the treatment of hormone-refractory prostate cancer. Synonyms: Cabazitaxel Impurity 32 (Mixture of Diastereomers); Cabazitaxel Impurity 20; (4S,5S)-2-(4-Methoxyphenyl)-4-phenyl-3-(1,1-dimethylethyl)ester-3,5-Oxazolidinedicarboxylic Acid; (4S,5S)-2-(4-Methoxyphenyl)-3-{[(2-methyl-2-propanyl)oxy]carbonyl}-4-phenyl-1,3-oxazolidine-5-carboxylic acid; 3,5-Oxazolidinedicarboxylic acid, 2-(4-methoxyphenyl)-4-phenyl-, 3-(1,1-dimethylethyl) ester, (4S,5S)-; (4S,5S)-3-(tert-Butoxycarbonyl)-2-(4-methoxyphenyl)-4-phenyloxazolidine-5-carboxylic acid. Grades: 98%. CAS No. 949459-78-3. Molecular formula: C22H25NO6. Mole weight: 399.44. | |
| Aluminium Oxide Powder | White crystalline powder, highly abrasive & refractory. Uses: abrasives, ceramics, refractories, polishing. Group: inorganic compound. Alternative Names: Alumina, Corundum. CAS No. 1344-28-1. |  |
| AP14145 hydrochloride | AP14145 hydrochloride is a potent K Ca 2 (SK) channel negative allosteric modulator with an IC 50 of 1.1 μM for K Ca 2.2 (SK2) and K Ca 2.3 (SK3) channels. AP14145 hydrochloride inhibition strongly depends on two amino acids, S508 and A533 in the channel. AP14145 hydrochloride prolonged atrial effective refractory period (AERP) in rats and demonstrates antiarrhythmic effects in a Vernakalant-resistant porcine model of atrial fibrillation (AF) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2387505-59-9. Pack Sizes: 5 mg. Product ID: HY-120355A. |  |
| AR-42 | AR-42 is an orally available, broad-spectrum deactylation inhibitor of both histone and non-histone proteins which play an important role in the regulation of gene expression, cell growth and survival. In preclinical studies, AR-42 has demonstrated greater potency and activity in solid and liquid tumors when compared to vorinostat and other deacetylase inhibitors. AR-42 is currently being studied in an investigator-initiated Phase I/IIa clinical study in adult patients with relapsed or refractory multiple myeloma, chronic lymphocytic leukemia or lymphoma. Synonyms: HDAC-42; HDAC42; HDAC 42; OSU-HDAC-42; OSU HDAC 42; AR-42; AR42; AR 42. Grades: 98%. CAS No. 935881-37-1. Molecular formula: C18H20N2O3. Mole weight: 312.37. | |
| Begelomab | Begelomab (SAND-26) is a murine IgG2b monoclonal antibody against DPP-4/CD26. Begelomab can be used for the research of severe refractory idiopathic inflammatory myopathy [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SAND-26. CAS No. 1403744-56-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99466. | |
| Belantamab | Belantamab is a humanized monoclonal antibody directed against the B-cell maturation antigen (BCMA). Belantamab can be used in the synthesis of Belantamab mafodotin, an ADC developed for the treatment of adult patients with relapsed or refractory multiple myeloma (RRMM). Synonyms: GSK2857914; GSK 2857914; GSK-2857914. CAS No. 2061894-48-0. | |
| Bexarotene, Free Acid (Targretin, Targretyn, Targrexin, LGD-1069, LG 1069, LG100069, SR-11247) | Bexarotene (LGD-1069) is a synthetic retinoid analog with specific affinity for the retinoid X receptor and belongs to a group of compounds called rexinoids. It is an oral, noncytotoxic drug that was approved in Europe and in the U.S.A. for the treatment of refractory advanced-stage cutaneous T-cell lymphomas (CTCL). Group: Biochemicals. Grades: Highly Purified. CAS No. 153559-49-0. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Bexarotene (Targretin, Targretyn, Targrexin, LGD-1069, LG 1069, LG100069, SR-11247) | Bexarotene (also called Targretin, Targretyn, Targrexin, LGD-1069, LG 1069, LG100069, SR-11247) is a synthetic retinoid analog with specific affinity for the retinoid X receptor and belongs to a group of compounds called rexinoids. It is an oral, noncytotoxic drug that was approved in Europe and in the U.S.A. for the treatment of refractory advanced-stage cutaneous T-cell lymphomas. The receptor-selective retinoids might be particularly useful in preventing ER-negative breast cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 153559-49-0. Pack Sizes: 5mg. Molecular Formula:C24H28O2 MOLECULAR WEIGHT: 348.48. US Biological Life Sciences. | Worldwide |
| blinatumomab | Blinatumomab is a monoclonal antibody used for the treatment of Philadelphia chromosome-negative relapsed or refractory acute lymphoblastic leukemia. It effects against tumor cells via binding to a CD3 site for T cells and a CD19 site for the target B cells, which express both in pediatric and adult populations. Uses: The treatment of philadelphia chromosome-negative relapsed or refractory acute lymphoblastic leukemia. Synonyms: Blincyto. CAS No. 853426-35-4. Molecular formula: C2367H3577N649O772S19. Mole weight: 54100. | |
| Boehmite Nanoparticles/Nanopowder | Boehmite Nanoparticles/Nanopowder. Uses: Abrasive materials, catalysts, flame retardant additive, circuit substrates, refractory materials, nanomedicine. Group: Oxides nanoparticles. | |
| Brostallicin hydrochloride | Brostallicin is a synthetic, alpha-bromoacrylic, second-generation minor groove binder (MGB), related to distamycin A, with potential antineoplastic activity. Brostallicin binds to DNA minor groove DNA, after having formed a highly reactive glutathione (GSH)-brostallicin complex in the presence of the enzyme glutathione S-transferase (GST), which is overexpressed in cancer cells; DNA replication and cell division are inhibited, resulting in tumor cell death. Compared to typical MGBs, this agent appears to bind covalently to DNA in a different manner and its activity does not depend on a functional DNA mismatch repair (MMR) mechanism. Accordingly, brostallicin may be effective against MMR-defective tumors that are refractory to various anticancer agents. Synonyms: PNU-166196; PNU 166196; PNU166196; 4-(2-bromoacrylamido)-N-(5-(5-(5-(2-guanidinoethylcarbamoyl)-1-methyl- 1H-pyrrol-3-ylcarbamoyl)-1-methyl-1H-pyrrol-3-ylcarbamoyl)-1-methyl-1H- pyrrol-3-yl)-1-methyl-1H-pyrrole-2-carboxamide. CAS No. 203258-38-2. Molecular formula: C30H36BrClN12O5. Mole weight: 760.05. | |
| Camlipixant | Camlipixant (BLU-5937) a potent, selective, non-competitive and orally active P2X3 homotrimeric receptor antagonist with an IC 50 of 25 nM against hP2X3 homotrimeric. Camlipixant shows potent anti-tussive effect and no taste alteration. Camlipixant can be used for the research of unexplained, refractory chronic cough [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BLU-5937. CAS No. 1621164-74-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136026. | |
| Carfilzomib | Carfilzomib is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. Group: Biochemicals. Alternative Names: (α S) -α - [ [2- (4-Morpholinyl) acetyl] amino] benzenebutanoyl-L-leucyl-N- [ (1S) -3-methyl-1- [ [ (2R) -2-methyl-2-oxiranyl] carbonyl] butyl] -L-phenylalaninamide; (α S) -α - [ (4-Morpholinylacetyl) amino] benzenebutanoyl-L-leucyl-N- [ (1S) -3-methyl-1- [ [ (2R) -2-methyloxiranyl] carbonyl] butyl] -L-phenylalaninamide; PR 171. Grades: Highly Purified. CAS No. 868540-17-4. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C40H57N5O7, Molecular Weight: 719.91. US Biological Life Sciences. | Worldwide |
| Carfilzomib Impurity 2 | Carfilzomib (2R,4S)-Diol is a derivative of Carflizomib , a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. Synonyms: (α S) ?-α -[[2- (4-Morpholinyl) ?acetyl]?amino]?benzenebutanoyl-L-leucyl-N-[ (1S, ?3R) ?-3, ?4-dihydroxy-3-methyl-1- (2-methylpropyl) ?-2-oxobutyl]?-L-phenylalaninamide. Grades: > 95%. CAS No. 1541172-75-1. Molecular formula: C40H59N5O8. Mole weight: 737.94. | |
| CG200745 | CG200745 is a novel hydroxamate-based pan-histone deacetylase inhibitor (HDACI). Like other inhibitors, CG200745 has the hydroxamic acid moiety to bind zinc at the bottom of catalytic pocket. CG200745 inhibited deacetylation of histone H3 and tubulin as much as vorinostat and belinostat did. CG200745 also inhibited growth of prostate cancer cells, increased sub-G1 population, and activated caspase-9, -3 and -8 in LNCaP, DU145 and PC3 cells. These results indicate that CG200745 induces apoptosis. The preclinical results show that combination treatment with docetaxel and new HDACI, CG200745, potentiated anti-tumor effect in hormone-refractory prostate cancer (HRPC) cells via activation of apoptosis. Synonyms: Ivaltinostat; CG-200745; CG-2; (E)-N1-(3-(dimethylamino)propyl)-N8-hydroxy-2-((naphthalen-1-yloxy)methyl)oct-2-enediamide. CAS No. 936221-33-9. Molecular formula: C24H33N3O4. Mole weight: 427.55. | |
| Clofarabine-5'-monophosphate | Clofarabine-5'-monophosphate is a prodrug form of clofarabine, an anti-cancer agent used to treat pediatric acute lymphoblastic leukemia and adult refractory or relapsed acute myeloid leukemia. It quickly converts into clofarabine-5'-triphosphate, which inhibits DNA synthesis and induces apoptosis in cancer cells. Grades: ≥ 95% by HPLC. CAS No. 134646-42-7. Molecular formula: C10H12ClFN5O6P (free acid). Mole weight: 383.66 (free acid). | |
| D,L-Sotalol, Hydrochloride (MJ-1999, Betapace, Darob, Sotacor, Sotalex) | A potent β-adrenergic-blocking agent. A class III antiarrythmic. It has been shown to prolong action potential and increases the refractory period. Group: Biochemicals. Alternative Names: N- [4- [1-Hydroxy-2- [ (1-methylethyl) amino] ethyl] phenyl] methanesulfonamide Hydrochloride; 4'- [1-Hydroxy-2- (isopropylamino) ethyl] methanesulfonanilide Hydrochloride; Betapace; DL-MJ 1999; Darob; MJ 1999; Sotacor; Sotalex; dl-Sotalol Hydrochloride. Grades: Highly Purified. CAS No. 959-24-0. Pack Sizes: 50mg, 100mg, 250mg, 500mg. Molecular Formula: C??H??ClN?O?S, Molecular Weight: 308.83. US Biological Life Sciences. | Worldwide |
| DL-threo-PDMP hydrochloride | DL-threo-PDMP hydrochloride is the hydrochloride form of DL-threo-PDMP that is a competitive glucosylceramide synthase ( GCS ) inhibitor. DL-threo-PDMP resensitizes refractory testicular germ cell tumors and epithelial ovarian cancer orthoxenografts to cisplatin in mice [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 80938-69-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-116392B. | |
| Eliapixant | Eliapixant (BAY 1817080) is a potent and selective antagonist of P2X3 receptor , with an IC 50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 1817080. CAS No. 1948229-21-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109170. | |
| Elotuzumab | Elotuzumab is a monoclonal antibody directed against the SLAMF7 receptor. Elotuzumab has no significant antimyeloma activity when given as a single agent with relapsed or refractory multiple myeloma (RRMM). Elotuzumab results in improved response and outcome when combined with other antimyeloma agents [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: HuLuc 63; PDL 063; BMS 901608. CAS No. 915296-00-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9965. | |
| Enasidenib mesylate | Enasidenib mesylate is a first-in-class, oral, potent, reversible, selective inhibitor of the IDH2 mutant enzymes indicated for the treatment of adult patients with replased or refractory acute myeloid leukemia (AML) with an isocitrate dehydrogenase-2 (IDH2) mutation. Synonyms: methanesulfonic acid;2-methyl-1-[[4-[6-(trifluoromethyl)pyridin-2-yl]-6-[[2-(trifluoromethyl)pyridin-4-yl]amino]-1,3,5-triazin-2-yl]amino]propan-2-ol; Enasidenib (mesylate); AG-221 mesylate; Enasidenib mesilate; Enasidenib methanesulfonate; Enasidenib mesylate [USAN]. CAS No. 1650550-25-6. Molecular formula: C20H21F6N7O4S. Mole weight: 569.48. | |
| Etripamil | Etripamil (MSP-2017) is a short-acting L-type calcium-channel antagonist, can be used for the research of Paroxysmal Supraventricular Tachycardia (PSVT). Etripamil (MSP-2017) slows atrioventricular nodal conduction and prolongs atrioventricular nodal refractory periods by inhibiting calcium ion influx through the calcium slow channels in the atrioventricular node cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MSP-2017; (-)-MSP-2017. CAS No. 1593673-23-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17611. | |
| Evinacumab | Evinacumab (REGN1500) is a human anti- ANGPTL3 ( angiopoietin-like protein 3 ) monoclonal antibody (IgG4 class antibody). Evinacumab reduces plasma lipids in dyslipidemic mice by blocking ANGPTL3. Evinacumab can be used in studies of homozygous familial hypercholesterolaemia (HoFH), refractory hypercholesterolaemia (both familial and non-familial) and severe hypertriglyceridaemia [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN1500. CAS No. 1446419-85-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99194. | |
| Fe-Co-Ni-Cr-Mo Spherical High-entropy Alloy (HEA) Powder | Spherical Refractory High-entropy Alloy Powder (Fe-Co-Ni-Cr-Mo) has high strength, high hardness, good high-temperature performance, excellent wear resistance, and corrosion resistance, which can be used in 3D printing. Alfa Chemistry provides spherical Refractory High-entropy Alloy Powder (Fe-Co-Ni-Cr-Mo) with high fluidity at a competitive price. Uses: Spherical heas powder has gained interest for its promising properties including enhanced irradiation resistance, high-temperature strength, and corrosion resistance. Group: High entropy alloys. Pack Sizes: Vacuum packaging, 1kg/bag, 2kg/bag; iron drum lined with plastic bag 25 kg/drum; special packaging is available according to user requirements. | |
| Fmoc-D-serine | N-Fmoc-D-serine is an N-Fmoc-protected form of D-Serine. D-Serine is a neurotransmitter that is concentrated in the mammalian brain, and is one of the very few amino acids that occur in the D- and L-configurations in significant amounts. D-Serine is a potent agonist of the N-methyl-D-aspartate (NMDA) receptor in the brain, which is associated with schizophrenia. Use of D-Serine has been considered as an additional therapy for refractory schizophrenic patients. Synonyms: Fmoc-D-Ser-OH; Fmoc-D-β-Hydroxyalanine; (R)-Fmoc-2-amino-3-hydroxypropionic acid. Grades: ≥ 98% (HPLC). CAS No. 116861-26-8. Molecular formula: C18H17NO5. Mole weight: 327.30. | |
| γ-(6-Aminohexyl)-ATP | γ-(6-Aminohexyl)-ATP, a pivotal biomedicine product, enacts a pivotal role in treating manifold cancers, as it targets refractory neoplastic cells and hinders their deleterious proliferation. This agent, also efficacious in ameliorating cognitive dysfunction in patients struggling with Alzheimer's and dementia, serves as a cutting-edge research tool for investigating diverse biological processes including DNA and protein synthesis. Synonyms: γ-(6-Aminohexyl)-adenosine-5'-triphosphate, Sodium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C16H29N6O13P3(free acid). Mole weight: 606.35 (free acid). | |
| Glofitamab | Glofitamab is a T-cell-engaging bispecific antibody possessing a novel 2:1 structure with bivalency for CD20 on B cells and monovalency for CD3 on T cells. Glofitamab is used as an effective therapy for relapsed or refractory diffuse large B-cell lymphoma. Synonyms: RO7082859; RG6026. CAS No. 2229047-91-8. | |
| Glofitamab | Glofitamab (RO7082859) is a T-cell-engaging bispecific antibody possessing a novel 2:1 structure with bivalency for CD20 on B cells and monovalency for CD3 on T cells. Glofitamab leads to T-cell activation, proliferation, and tumor cell killing upon binding to CD20 on malignant cells. Glofitamab induces durable complete remissions in relapsed or refractory B-Cell non-Hodgkin lymphoma (B-NHL) [1] [2] [3] [4]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: RO7082859. CAS No. 2229047-91-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99024. | |
| Hafnium Diboride HfB2 Powder | Hafnium Diboride HfB2 Powder. Uses: Hafnium diboride is widely used in wear-resistant coatings, refractory materials, cutting tools and aerospace thermal protection systems and other fields. Group: Boride powders. CAS No. 12007-23-7. Molecular formula: 200.11. Mole weight: HfB2. >99.5%. | |
| Hafnium(IV) carbide | Hafnium carbide (HfC) with a melting point over 3890°C is a refractory binary compound. HfC and NbC can also be used as refractory coatings in nuclear reactors. The mixed carbide Ta4HfC5 possesses the highest melting point of any currently known compound at 4215°C. Group: Metal & ceramic materials. Alternative Names: HAFNIUM CARBIDE;Hafnium carbide ceramics;HAFNIUM(IV) CARBIDE, ;HAFNIUM(IV) CARBIDE-325MESH;hafnium(iv) carbide;HAFNIUM CARBIDE , 45 MICRON;Hafnium carbide, 99.5% (metals basis excluding Zr), Zr ;Hafnium carbide/ 99+%. CAS No. 12069-85-1. Molecular formula: HfC. Mole weight: 190.5. Purity: 0.995. Catalog: ACM12069851. |  |
| Herg Activator (NS1643, 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea, Human ether-a-go-go related gene (hERG) K+ channel activator, KV11.1 Channel Activator) | A diphenolurea compound that selectively activates human ether-a-go-go-related gene (hERG) K+-channel (EC50=10.5uM). Shown to significantly increase both steady-state and peak tail currents of hERG channels, but exhibits only a trivial effect on Kv4.3 and Kv1.5 channels. Causes a significant reduction in action potential duration (APD90) in patch clamp assays in Xenopus oocytes, HEK293 cells, and guinea pig cardiamyocyes that can be reversed by the addition of E-4031, a specific blocker of hERG channels. Also shown to activate IKr channel in cardiomyocytes and increase post-repolarization refractory time thereby alleviating hyper-excitability and producing antiarrhythmic effects. It can also restore IKr reduced by down-regulation of IKr expression. Group: Biochemicals. Grades: Highly Purified. CAS No. 448895-37-2. Pack Sizes: 10mg. Molecular Formula: C??H??F?N?O?, Molecular Weight: 380.2. US Biological Life Sciences. | Worldwide |
| Iadademstat | Iadademstat (ORY-1001) is a highly potent, orally active and selective LSD1 (KDM1A) inhibitor with antileukemic activity. Iadademstat can be used for relapsed or refractory acute myeloid leukemia research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ORY-1001. CAS No. 1431304-21-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-109117. | |
| Ibrutinib Dimer | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: Ibrutinib impurity MDAEJ; 2-Propen-1-one, 1-[(3R)-3-[4-[[3-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-3-oxopropyl]amino]-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-; 1-((R)-3-(4-((3-((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl)amino)-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one. Grades: ≥95%. CAS No. 2031255-23-7. Molecular formula: C50H48N12O4. Mole weight: 880.99. | |
| Ibrutinib Impurity 1 | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: 1-Piperidinecarboxylic acid, 3-[4-aMino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyriMidin-1-yl]-, 1,1-diMethylethyl ester, (3R)-; (R)-tert-Butyl 3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate. Grades: > 95%. CAS No. 1022150-11-3. Molecular formula: C27H30N6O3. Mole weight: 486.58. | |
| Ibrutinib Impurity HNEJ | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Grades: ≥95%. Molecular formula: C49H46N12O4. Mole weight: 866.99. | |
| Ibrutinib Impurity IMYBJ | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Grades: ≥95%. Molecular formula: C20H19N5O. Mole weight: 345.41. | |
| Ibrutinib Impurity JXBJ | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Grades: ≥95%. Molecular formula: C26H26N6O2. Mole weight: 454.53. | |
| Ibrutinib Impurity MDDYH | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Grades: ≥95%. CAS No. 2052279-49-7. Molecular formula: C25H24N6O3. Mole weight: 456.51. | |
| Ibrutinib Impurity SMSJ | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Grades: ≥95%. Molecular formula: C32H24N8O2. Mole weight: 552.60. | |
| Ibrutinib Methoxy Impurity | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-methoxypropan-1-one; Ibrutinib impurity JYD. Grades: ≥95%. CAS No. 2031255-26-0. Molecular formula: C26H28N6O3. Mole weight: 472.55. | |
| Idelalisib | Idelalisib is a kinase inhibitor. In combination with rituximab, it was used for the treatment of relapsed or refractory chronic lymphocytic leukemia (CLL). Uses: The treatment of chronic lymphocytic leukemia (cll). Synonyms: Idelalisib; CAL101; CAL 101; CAL-101; GS1101; GS 1101; GS-1101, Idelalisib. Grades: > 95%. CAS No. 870281-82-6. Molecular formula: C22H18FN7O. Mole weight: 415.432. | |
| INOTUZUMAB OZOGAMICIN | INOTUZUMAB OZOGAMICIN is an antibody-drug conjugate targeting CD22 for the treatment of adults with relapsed or refractory CD22-positive B-cell precursor acute lymphoblastic leukemia (ALL). Uses: The treatment of acute lymphoblastic leukemia (all). Synonyms: Besponsa. CAS No. 635715-01-4. Molecular formula: C73H96IN6O25S3. Mole weight: 1680.67. | |
| Kaolin | Kaolin is a clay that is essentially kaolinite, a hydrated aluminum silicate. It has a high fusion point and is the most refractory of all clays. In oral medicines, kaolin is used as a diluent in tablet and capsule preparations. It is also used as a suspending vehicle. Therapeutically, kaolin has been used as an oral antidiarrheal agent. Uses: Hair care, soap, body care, face care. Synonyms: Hydrated aluminum silicate; Bolus alba; ASP; Acidic white clays; Alfaplate; Alpha-Print; Alphacoat; Alphacote; Alphagloss; Alphalux 91; Altowhite; Apsilex; Argiflex; Argil; Argilla; Asphaltex; Astra-Cote; Astra-Glaze; Astra-Plate; Astracote 90; Astrasheen; BSK-H; Barden clay; Barrisurf HX; Barrisurf LX; CMP. Grades: ≥95%. CAS No. 1332-58-7. Molecular formula: Al2H4O9Si2. Mole weight: 258.16. | |
| Lucatumumab | Lucatumumab (HCD122) is a fully human anti-CD40 antagonist monoclonal antibody, which blocks CD40/CD40L-mediated signaling. Lucatumumab efficiently mediates antibody-dependent cell-mediated cytotoxicity (ADCC) and clearance of tumor cells, can be used for refractory lymphomas, CLL and multiple myeloma research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: HCD122. CAS No. 903512-50-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99167. | |
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