Release Agent Suppliers USA

Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.

Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.

Product
1,5-Isoquinolinediol 1,5-Isoquinolinediol is a PARP1 inhibitor (IC50 value 0.39 - 1.00 μM) and neuroprotective agent leading to an increase up to 8-fold in the absolute frequency of gene targeting in the correction of the mutation at the stable integrated HSV tk gene in mouse Ltk cells. 1,5-Isoquinolinediol is also an inducible nitric oxide synthase (NOS2) inhibitor. 1,5-Isoquinolinediol significantly inhibited mitochondrial membrane potential loss, AIF (apoptosis inducing factor) and cytochrome c release from the mitochondria. Uses: Poly(adp-ribose) polymerase inhibitors. Synonyms: 1,5-Dihydroxyisoquinoline; Isoquinoline-1,5-diol; 5-Hydroxy-1(2H)-isoquinolinone; 5-Hydroxyisocarbostyril. Grades: 99%. CAS No. 5154-2-9. Molecular formula: C9H7NO2. Mole weight: 161.16. BOC Sciences 10
1-Aminohydantoin hydrochloride 1-Aminohydantoin hydrochloride is a major metabolite of nitrofurantoin in animal tissues and can be used as a standard for the determination of residues of veterinary agents in meat, milk et.al. 1-Aminohydantoin hydrochloride covalently binds to tissue proteins and is released from the tissues under slightly acidic conditions and derivatized with 2-nitrobenzaldehyde to form nitrophenyl derivatives of AHD before detection [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2827-56-7. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-Y0469. MedChemExpress MCE
1-Chloroacenaphthene 1-Chloroacenaphthene is a chlorinated derivative of acenaphthene, a polycyclic hydrocarbon that has potential to act as polyploidizing agents in plants. 1-Chloroacenaphthene is a polyaromatic hydrocarbon that is released into the atmosphere by means of incomplete combustion processes (e.g. diesel exhaust). Group: Biochemicals. Grades: Highly Purified. CAS No. 40745-49-1. Pack Sizes: 25mg, 250mg. Molecular Formula: C12H9Cl. US Biological Life Sciences. USBiological 9
Worldwide
1-Dodecylimidazole 1-Dodecylimidazole (N-Dodecylimidazole) is a lysosomotropic detergent and a cytotoxic agent. 1-Dodecylimidazole causes cell death by its acid-dependent accumulation in lysosomes, disruption of the lysosomal membrane, and releaseof cysteine proteases into the cytoplasm. 1-Dodecylimidazole has hypocholesterolaemic activity and broad-spectrum antifungal activity [1] [2] [3]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: N-Dodecylimidazole. CAS No. 4303-67-7. Pack Sizes: 500 mg; 1 g. Product ID: HY-138540. MedChemExpress MCE
1-Dodecylimidazole 1-Dodecylimidazole (N-Dodecylimidazole) is a lysosomotropic detergent and a cytotoxic agent. 1-Dodecylimidazole causes cell death by its acid-dependent accumulation in lysosomes, disruption of the lysosomal membrane, and releaseof cysteine proteases into the cytoplasm. 1-Dodecylimidazole has hypocholesterolaemic activity and broad-spectrum antifungal activity. Group: Inhibitors. Alternative Names: 1-DODECYLIMIDAZOLE;1-DODECYL-1H-IMIDAZOLE;1-dodecyl-1h-imidazol;1-dodecyl-imidazol;1-laurylimidazole;n-laurylimidazole;N-DODECYLIMIDAZOLE;1-Dodecylimidazole,95%. CAS No. 4303-67-7. Molecular formula: C15H28N2. Mole weight: 236.4. Appearance: Clourless Liquid. Purity: 0.98. IUPACName: 1-dodecylimidazole. Canonical SMILES: CCCCCCCCCCCCN1C=CN=C1. ECNumber: 224-314-4. Catalog: ACM4303677. Alfa Chemistry.
2,3-Dimethyl-6-tert-butyldimethylsilyl-b-cyclodextrin 2,3-Dimethyl-6-tert-butyldimethylsilyl-b-cyclodextrin, a compound widely employed in the biomedical field, plays a pivotal role in enhancing drug efficacy through its distinct structural properties. This versatile agent facilitates the solubilization and regulated release of drugs afflicted with poor solubility or instability. Its profound implications extend to formulating treatments for ailments including but not limited to cancer, cardiovascular disorders, and neurodegenerative maladies. Synonyms: 2, 3-Di-O-methyl-6-O-tert-butyldimethylsilyl) cyclomaltoheptaose Heptakis(2,3-di-O-methyl-6-O-tert-butyldimethylsilyl)-b-cyclodextrin. CAS No. 123155-04-4. Molecular formula: C98H196O35Si7. Mole weight: 2131.18. BOC Sciences
2-Hydroxy-3-phenoxypropyl acrylate 2-Hydroxy-3-phenoxypropyl acrylate. Uses: Polymeric membranes for controlled drug release systems may be prepared by the photosynthesis of 2-hydroxy-3-phenoxypropyl acrylate by uv radiation. tthe product can be used as a curing agent during the fabrication of poly (phenylene ether)-based substrate materials. Group: Monomers. Alternative Names: (2-Hydroxy-3-phenoxypropyl) prop-2-enoate, 3-Phenoxy-2-hydroxypropyl acrylate. CAS No. 16969-10-1. Pack Sizes: Packaging 100 mL in poly bottle. Product ID: (2-hydroxy-3-phenoxypropyl) prop-2-enoate. Molecular formula: 222.24. Mole weight: H2C=CHCO2CH2CH(OH)CH2OC6H5. OC(COC(=O)C=C)COc1ccccc1. 1S/C12H14O4/c1-2-12 (14)16-9-10 (13)8-15-11-6-4-3-5-7-11/h2-7, 10, 13H, 1, 8-9H2. HHQAGBQXOWLTLL-UHFFFAOYSA-N. Alfa Chemistry Materials 6
2-Hydroxy-3-phenoxypropyl acrylate Polymeric membranes for controlled drug release systems may be prepared by the photosynthesis of 2-hydroxy-3-phenoxypropyl acrylate by UV radiation. Tthe product can be used as a curing agent during the fabrication of poly (phenylene ether)-based substrate materials. Group: Polymer/macromolecule. Alternative Names: (2-Hydroxy-3-phenoxypropyl) prop-2-enoate, 3-Phenoxy-2-hydroxypropyl acrylate. CAS No. 16969-10-1. Molecular formula: H2C=CHCO2CH2CH(OH)CH2OC6H5. Mole weight: 222.24. IUPACName: (2-hydroxy-3-phenoxypropyl) prop-2-enoate. Canonical SMILES: OC(COC(=O)C=C)COc1ccccc1. Density: 1.16 g/mL at 25 °C (lit.). ECNumber: 241-045-8. Catalog: ACM16969101-1. Alfa Chemistry. 2
2-Methyl-3-[(2S)-2-pyrrolidinylmethoxy]-pyridine Dihydrochloride 2-Methyl-3-[(2S)-2-pyrrolidinylmethoxy]-pyridine Dihydrochloride is a selective neuronal nicotinic receptor (NNR) modulator and a neuroprotective agent that has therapeutic potential for treating cognitive disorders. 2-Methyl-3-[(2S)-2-pyrrolidinylmethoxy]-pyridine Dihydrochloride is selective for the neuronal nicotinic acetylcholine receptors (nAChRs) subtype, which modulate the release of neurotransmitters (acetylcholine and dopamine). Group: Biochemicals. Grades: Highly Purified. CAS No. 161416-61-1. Pack Sizes: 5mg, 10mg. Molecular Formula: C11H16N2O 2HCl, Molecular Weight: 192.267292. US Biological Life Sciences. USBiological 10
Worldwide
(+)-[6]-Gingerol (+)-[6]-Gingerol is a bioactive compound found in ginger (Zingiber officinale) with antioxidant activity, which functions as an anti-inflammatory and antitumor agent. (+)-[6]-Gingerol down regulates proinflammatory cytokine release by macrophages. (+)-[6]-Gingerol has been shown to inhibit COX-2 expression by blocking the activation of p38 MAP kinase and NF-κB in phorbol ester-stimulated mouse skin. Group: Biochemicals. Alternative Names: (5S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-decanone; (S)-(+)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-decanone; (+)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-decanone; (5S)-[6]-Gingerol; (S)-(+)-[6]Gingerol; (S)-[6]Gingerol; [6]-Gingerol. Grades: Highly Purified. CAS No. 23513-14-6. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 2
Worldwide
8-[(6-Amino)hexyl]-amino-adenosine-2',5'-bisphosphate - ATTO-700 ATTO-700, a fluorescent dye widely utilized in biomedical research for protein and cell labeling, boasts exceptional spectral properties. This feature alone renders it invaluable for imaging inquiries, though it offers much more. Employing ATTO-700, researchers have probed into cancer cell glucose uptake, stem cell geographical activity, and the release plus distribution of therapeutic agents. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-2',5'-bisphosphate, labeled with ATTO 700, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H29N7O10P2- ATTO 700 (free acid). Mole weight: 1088.39 (free acid). BOC Sciences 2
Abarelix Abarelix is a synthetic decapeptide and antagonist of naturally occurring gonadotropin-releasing hormone (GnRH). Abarelix directly and competitively binds to and blocks the gonadotropin releasing hormone receptor in the anterior pituitary gland, thereby inhibiting the secretion and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH). In males, the inhibition of LH secretion prevents the release of testosterone. As a result, this may relieve symptoms associated with prostate hypertrophy or prostate cancer, since testosterone is required to sustain prostate growth. Check for active clinical trials or closed clinical trials using this agent. Synonyms: Plenaxis, PPI-149; PPI 149; PPI149; R-3827; R 3827; R3827. Grades: 98%. CAS No. 183552-38-7. Molecular formula: C72H95ClN14O14. Mole weight: 1416.09. BOC Sciences
Agar Agar is used as an emulsifier, stabilizer, suspending agent, sustained-release agent, tablet binder, thickener and viscosity-increasing agent. Synonyms: Agar-agar; Agar-agar flake; Agar-agar gum; Bengal gelatin; Bengal gum; Bengal isinglass; Ceylon isinglass; Chinese isinglass; E406; gelosa; Japan agar; Japan isinglass; layor carang. Grades: 98%. CAS No. 9002-18-0. Molecular formula: (C12H18O9)n. Mole weight: 336.33500. BOC Sciences
Aladorian Aladorianis is a ryanodine receptor calcium release channel modulator. It is an antiarrhythmic agent. Clinical development for Chronic heart failure and Ventricular tachycardia was discontinued. Uses: Chronic heart failure; ventricular tachycardia. Synonyms: 2,3-Dihydro-7-methoxy-α-oxo-1,4-benzothiazepine-4(5H)-acetic Acid; ARM036; ARM-036; ARM 036; S36; S44121-1; Aladorian; Aladorian; S 36; S 44121-1. Grades: 98%. CAS No. 865433-00-7. Molecular formula: C12H13NO4S. Mole weight: 267.30. BOC Sciences
Alginic Acid Alginic acid is a tasteless, practically odorless, white to yellowish white, fibrous powder. Synonyms: Acidum alginicum; E400; Kelacid; L-gulo-D-mannoglycuronan; polymannuronic acid; Protacid; Satialgine H8. CAS No. 9005-32-7. Product ID: PE-0139. Molecular formula: (C6H8O)n. Mole weight: 20000 ~ 240000. Category: Stabilizing Agents; Suspending Agents; Sustained Release Agents; Tablet Binder; Tablet Dsintegrant; Viscosity-increasing Agents. Product Keywords: Binder Excipients; Stabilizers; Suspending Agents; ; PE-0139; Alginic Acid; Stabilizing Agents; Suspending Agents; Sustained Release Agents; Tablet Binder; Tablet Dsintegrant; Viscosity-increasing Agents; (C6H8O)n; 9005-32-7. UNII: 8C3Z4148WZ. Chemical Name: Alginic acid. Grade: Pharmceutical Excipients. Administration route: Ophthalmic, oral. Dosage Form: Ophthalmic preparations, oral capsules, and tablets. Stability and Storage Conditions: Alginic acid hydrolyzes slowly at warm temperatures producing a material with a lower molecular weight and lower dispersion viscosity.Alginic acid dispersions are susceptible to microbial spoilage on storage, which may result in some depolymerization and hence a decrease in viscosity. Dispersions should therefore be preserved with an antimicrobial preservative such as benzoic acid; potassium sorbate; sodium benzoate; sorbic acid; or paraben. Concentrations of 0.1-0.2% are usually used. Alginic acid dispersions may be sterilize… CD Formulation
Allethrin Allethrin, a pyrethroid insecticide is a major mosquito repellent agent. Allethrin induces oxidative stress, apoptosis and calcium release in rat testicular carcinoma cells (LC540). Allethrin induces BCL-2, caspase-3 activation and release of intracellular calcium [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 584-79-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B1559. MedChemExpress MCE
Amine/Alkoxy Functional Silicone Fluid It is used as a release agent, room temperature curing sealant, paint, adhesive and detergent resistant polishing agent. Group: Silicone. CAS No. 110475-02-0. Appearance: Clear to hazy, colorless to straw liquid. Catalog: ACM110475020. Alfa Chemistry. 2
Amrinone Amrinone is a selective cAMP phosphodiesterase (PDE-3) inhibitor with positive inotropic and vasodilatory activity. It is a simple, non-glycoside cardiotonic agent. It provides protection against ischemia-reperfusion injury in kidney, liver, and heart. It has the ability to stimulate calcium ion influx into the cardiac cell. It is used in the treatment of congestive heart failure. It increases cardiac contractility as a vasodilator. It acts by inhibiting the breakdown of both cAMP and cGMP by the phosphodiesterase (PDE3) enzyme. It is a drug that may improve the prognosis in patients with congestive heart failure. It has been shown to increase the contractions initiated in the heart by high gain calcium induced calcium release (CICR). It was developed by Sanofi and has been listed. Uses: Amrinone is a simple, non-glycoside cardiotonic agent. it provides protection against ischemia-reperfusion injury in kidney, liver, and heart. it is used in the treatment of congestive heart failure. it increases cardiac contractility as a vasodilator. Synonyms: Inamrinone; Wincoram; Inocor; Cordemcura; Win-40680; Win40680; 3-Amino-5-pyridin-4-yl-1H-pyridin-2-one. Grades: 98%. CAS No. 60719-84-8. Molecular formula: C10H9N3O. Mole weight: 187.20. BOC Sciences
AR 231453 AR231453 is a potent and selective small molecule agonist of GPR119 that enhances glucose-dependent insulin secretion and glucagon-like peptide 1 (GLP-1) release. It is Antidiabetic agent. Synonyms: AR231453; AR-231453; AR 231453; AR-231,453; AR231,453; AR231,453. Grades: >98%. CAS No. 733750-99-7. Molecular formula: C21H24FN7O5S. Mole weight: 505.52. BOC Sciences 2
BAY 11-7082 IkappaBalpha kinase inhibitor. NF-kappaB inhibitor. Potential anti-inflammatory agent. Apoptosis inducer. Inhibits the release of proinflammatory cytokines. Inflammasome inhibitor Inhibits platelet aggregation. Group: Biochemicals. Alternative Names: (E)-3-(4-Methylphenylsulfonyl)-2-propenenenitrile. Grades: Highly Purified. CAS No. 19542-67-7. Pack Sizes: 10mg, 50mg. Molecular Formula: C10H9NO2S. US Biological Life Sciences. USBiological 3
Worldwide
Behenamide Behenamide is a fatty acid derived from plants such as rapeseed oil and can be synthesized by a variety of processes. Behenamide has unique properties that make it useful as a slip agent, A lubricant and release agent, it is also used in personal care products, including cosmetics and hair care, as a thickener and emollient because of its ability to improve the consistency and texture of formulations. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Docosanamide. CAS No. 3061-75-4. Pack Sizes: 1 g; 5 g. Product ID: HY-W127445. MedChemExpress MCE
Bentonite Bentonite is a crystalline, claylike mineral, and is available as an odorless, pale buff, or cream to grayish-colored fine powder, which is free from grit. It consists of particles about 50-150 mm in size along with numerous particles about 1-2 mm. Microscopic examination of samples stained with alcoholic methylene blue solution reveals strongly stained blue particles. Bentonite may have a slight earthy taste. Synonyms: Albagel; bentonitum; E558; mineral soap; Polargel; soap clay; taylorite; Veegum HS; wilkinite. CAS No. 1302-78-9. Product ID: PE0361. Molecular formula: Al2O3`4SiO2`H2O. Mole weight: 359.16. Category: Adsorbent; Suspending Agents; Thickener; Dairy Stabilizer; Stabilizer. Product Keywords: Suspending Agents; Adsorbents; Stabilizers; ; PE0361; Bentonite; Adsorbent; Suspending Agents; Thickener; Dairy Stabilizer; Stabilizer; Al2O3`4SiO2`H2O; 1302-78-9. UNII: A3N5ZCN45C. Chemical Name: Bentonite. Grade: Pharmceutical Excipients. Administration route: Dental; Oral; Topical; Transdermal. Dosage Form: Oral capsules, tablets, and suspensions, topical suspensions, controlled-release transdermal films, and pessaries. Stability and Storage Conditions: Bentonite is hygroscopic and should avoid absorbing moisture from the environment. The bentonite aqueous suspension can be sterilized by autoclaving. After the solid bentonite was dried at 100°C, it was kept at 170°C for 1 hour for dry heat sterilization. This product … CD Formulation
Bombesin Bombesin is a neuropeptide with many biological effects such as hormone release, activation of pancreatic enzyme secretion, inhibition of gastric emptying and modulation of gastric acid secretion. It binds to the gastrin-releasing peptide receptor (GRPR) in rat pancreatic acinar cells (Ki = 1.88 nM), and also to frog bombesin receptor subtype 4 (BB4) in CHO cells overexpressing the receptor (Ki = 1.7 nM). Uses: Neurotransmitter agents. Synonyms: H-Pyr-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2; L-pyroglutamyl-L-glutaminyl-L-arginyl-L-leucyl-glycyl-L-asparagyl-L-glutaminyl-L-tryptophyl-L-alanyl-L-valyl-glycyl-L-histidyl-L-leucyl-L-methioninamide; Glp-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2. Grades: ≥95%. CAS No. 31362-50-2. Molecular formula: C71H110N24O18S. Mole weight: 1619.85. BOC Sciences 8
Bretylium Tosylate Bretylium Tosylate, a class III antiarrhythmic agent, is an inhibitor of the presynaptic release of vasoconstrictive neurotransmitters and a blocker of sympathetic and adrenergic nerves. Synonyms: 2-Bromo-N-ethyl-N,N-dimethylbenzenemethanaminium 4-Methylbenzenesulfonate; (o-Bromobenzyl)ethyldimethylammonium p-Toluenesulfonate; (o-Bromobenzyl)ethyldimethylammonium p-Toluenesulfonate; ASL 603; Bretylan; Bretylate; Bretylium p-Toluenesulfonate; Bretylium Tosilate; Bretylol; Darenthin; N-Ethyl-N-(o-bromobenzyl)-N,N-dimethylammonium Tosylate; NSC 62164; Ornid. Grades: ≥95%. CAS No. 61-75-6. Molecular formula: C18H24BrNO3S. Mole weight: 414.36. BOC Sciences 8
Bretylium Tosylate Bretylium tosylate has a biphasic response, initially inducing norepinephrine release followed by sympathetic ganglionic blockade. Bretylium tosylate is a class III antiarrhythmic agent and a competitive inhibitor of acetylcholinesterase. Group: Biochemicals. Alternative Names: 2-Bromo-N-ethyl-N, N-dimethyl Benzene methanaminium 4-Methyl Benzene sulfonate; (o-Bromobenzyl) ethyldimethylammonium p-Toluenesulfonate; (o-Bromobenzyl) ethyldimethylammonium p-Toluenesulfonate; ASL 603; Bretylan; Bretylate; Bretylium p-Toluenesulfonate; Bretylium Tosilate; Bretylol; Darenthin; N-Ethyl-N-(o-bromobenzyl)-N,N-dimethylammonium Tosylate; NSC 62164; Ornid. Grades: Highly Purified. CAS No. 61-75-6. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 2
Worldwide
Broxyquinoline Broxyquinoline is an antiprotozoal agent and able to release oxygen free radicals from the water in mucous membranes. Synonyms: Broxyquinoline; NSC 1810; NSC-1810; NSC1810; Dibromoxyquinoline; UCB 5055; UCB-5055; UCB5055; Paramibe; Brodiar. Grades: >98%. CAS No. 521-74-4. Molecular formula: C9H5Br2NO. Mole weight: 302.95. BOC Sciences 10
Bufexamac Bufexamac is a COX inhibitor for IFN-α release with EC50 of 8.9 μM.Bufexamac is a drug used as an anti-inflammatory agent on the skin, as well as rectally. Common brand names include Paraderm and Parfenac. It was withdrawn in Europe because of allergic reactions. Synonyms: Benzeneacetamide, 4-butoxy-N-hydroxy-; 4-Butoxy-N-hydroxybenzeneacetamide; Acetohydroxamic acid, 2-(p-butoxyphenyl)-; 2-(4-Butoxyphenyl)acetohydroxamic acid; 2-(p-Butoxyphenyl)acetohydroxamic acid; 4-Butoxyphenylacethydroxamic acid; Anderm; Bufexamic acid; CP 1044J3; Droxarol; Droxaryl; Feximac; Flogocid; Flogocid N plastigel; Malipuran; Mofenar; Norfemac; p-Butoxyphenylacethydroxamic acid; p-Butoxyphenylacetohydroxamic acid; Parfenac; Parfenal; Trolab. Grades: >98%. CAS No. 2438-72-4. Molecular formula: C12H17NO3. Mole weight: 223.27. BOC Sciences 10
Calcium Estearate Calcium Estearate. Uses: Plastic industry: lubricant and mold release additive in the manufacture of plastics, mainly pvc. -pharmaceutical industry: lubricating and sliding agent in the production of tablets and capsules. -cosmetics and personal care industry: stabilizing and thickening agent in cosmetic and personal care products, such as creams, lotions and makeup. -paints and coatings industry: dispersing and thickening agent in paints and coatings. -food industry: food additive in small amounts as a defoaming and stabilizing agent in powdered food products, such as instant drink mixes. -rubber industry: mold release agent and stabilizer in the manufacture of rubber products. helps prevent adhesion of rubber to molds and improves the thermal stability of the material. CAS No. 1305-62-0. Pack Sizes: Bags. TZ GROUP INC
Calcium Polycarbophil It is used as an adsorbent, bioadhesive material, controlled-release agent, emulsifier, suspending agent, tablet binder and thickener. Synonyms: Calcium polycarbophil; Colonel. Grades: 95%. CAS No. 126040-58-2. BOC Sciences
Carbomer Carbomers are used as rheology modifiers in liquid or semi-solid pharmaceutical formulations. In tablet formulations, carbomers are used as controlled release agents and/or binders. Synonyms: Carboxypolymethylene resin;Poly(acrylic acid). Grades: 95%. CAS No. 9007-20-9. Molecular formula: C3H4O2. BOC Sciences
Carbomer Carbomers are white-colored, ‘fluffy, acidic, hygroscopic powders with a characteristic slight odor. A granular carbomer is also available (Carbopol 71G). Synonyms: Acrypol; Acritamer; acrylic acid polymer; carbomera; Carbopol; carboxy polymethylene; polyacrylic acid; carboxyvinyl polymer; Pemulen; Tego Carbomer. CAS No. 9003-1-4. Product ID: PE-0469. Category: Bioadhesive Material; Controlled-release Agents; Emulsifying Agents; Emulsion Stabilizer; rheology modifier; Stabilizing Agents; Suspending Agents; Tablet Binder. Product Keywords: Suspending Agents; Emulsifier Excipients; Binder Excipients; ; PE-0469; Carbomer; Bioadhesive Material; Controlled-release Agents; Emulsifying Agents; Emulsion Stabilizer; rheology modifier; Stabilizing Agents; Suspending Agents; Tablet Binder; ; 9003-01-4. UNII: 9G2MAD7J6W. Chemical Name: Carbomer. Grade: Pharmceutical Excipients. Administration route: Oral; ophthalmic, rectal, topical, transdermal ; vaginal. Dosage Form: Oral suspensions, tablets; ophthalmic, rectal, topical, transdermal preparations; vaginal suppositories. Stability and Storage Conditions: Carbomers are stable, hygroscopic materials that may be heated at temperatures for up to 2 hours without affecting their thickening efficiency. However, exposure to excessive temperatures can result in discoloration and reduced stability. Complete decomposition occurs with heating for 30 minutes at 260°C. Dry powder forms of carbomer… CD Formulation
Carbomer 941 Carbomer 941 (CBM 941) is an acrylic acid polymer, which can be used as a thickening agent. Carbomer 941 which forms a high viscosity gel, provides a stable gel matrix, and exhibits good heat, light and microbial contamination resistance. Carbomer 941 facilitates the drug release and local application, which can be used in the pharmaceutical industry [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: CBM 941. CAS No. 9007-20-9. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-W250721C. MedChemExpress MCE
Carbomer 980 Carbomer 980 (CBM 980) is an acrylic acid polymer, which can be used as a thickening agent. Carbomer 980 provides a stable gel matrix, exhibits good heat, light and microbial contamination resistance. Carbomer 980 facilitates the drug release and local application, which can be used in the pharmaceutical industry [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: CBM 980. CAS No. 9007-20-9. Pack Sizes: 25 g. Product ID: HY-W250721. MedChemExpress MCE
Carboxyamidotriazole orotate Carboxyamidotriazole orotate (CTO) is the orotate salt form of carboxyamidotriazole (CAI), an orally bioavailable small molecule with potential antiangiogenic and antiproliferative activities. Carboxyamidotriazole binds to and inhibits non-voltage-operated calcium channels, blocking both Ca2+ influx into cells and Ca2+ release from intracellular stores, resulting in the disruption of calcium channel-mediated signal transduction. CAI inhibits PI3 activity and vascular endothelial growth factor (VEGF) signaling. This may inhibit endothelial proliferation, tumor cell growth, invasion and metastasis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus). Synonyms: L-651582 Orotate; CAI Orotate; CTO; 4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-, compd. with 5-amino-1-[[3,5-dichloro-4-(4-chlorobenzoyl)phenyl]methyl]-1H-1,2,3-triazole-4-carboxamide (1:1); 2,6-Dioxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylic acid 5-amino-1-[3,5-dichloro-4-(4-chlorobenzoyl)benzyl]-1H-1,2,3-triazole-4-carboxamide (1:1). Grades: ≥90%. CAS No. 187739-60-2. Molecular formula: C22H16Cl3N7O6. Mole weight: 580.76. BOC Sciences 11
Carrageenan Carrageenan, when extracted from the appropriate seaweed source, is a yellow-brown to white colored, coarse to fine powder that is odorless and tasteless. Synonyms: Chondrus extract; E407; Gelcarin; Genu; Grindsted; Hygum TP-1; Irish moss extract; Marine Colloids; SeaSpen PF; Viscarin. Product ID: PE-0639. Category: Emulsifying Agents; Stabilizing Agents; Suspending Agents; Sustained-release Agents; Viscosity-increasing Agents. Product Keywords: Excipients for Liquid Dosage Form; Suspending Agents; PE-0639; Carrageenan; Emulsifying Agents; Stabilizing Agents; Suspending Agents; Sustained-release Agents; Viscosity-increasing Agents;. UNII: 5C69YCD2YJ. Grade: Pharmceutical Excipients. Stability and Storage Conditions: Carrageenan is a stable, though hygroscopic, polysaccharide and should be stored in a cool, dry place. Carrageenan in solution has maximum stability at pH 9 and should not be heat processed at pH values below 3.5. Acid and oxidizing agents may hydrolyze carrageenan in solution leading to loss of physical properties through cleavage of glycosidic bonds. Acid hydrolysis depends on pH, temperature and time. The acid hydrolysis takes place only when the carrageenan is dissolved, and the hydrolysis is accelerated as the processing temperature and/or the processing time is increased. However, when the carrageenan is in its gelled state the acid hydrolysis no longer takes place. Source and Preparation: The main sp… CD Formulation
Ceratonia Ceratonia occurs as a yellow-green or white colored powder. Although odorless and tasteless in the dry powder form, ceratonia acquires a leguminous taste when boiled in water. Synonyms: Algaroba; carob bean gum; carob flour; ceratonia gum; ceratonia siliqua; ceratonia siliqua gum; Cheshire gum; E410; gomme de caroube; locust bean gum; Meyprofleur; St Johns bread. CAS No. 9000-40-2. Product ID: PE-0468. Category: Controlled-release Agents; Stabilizing Agents; Suspending Agents; Tablet Binder; Viscosity-increasing Agents. Product Keywords: Binder Excipients; Stabilizers; Suspending Agents; ; PE-0468; Ceratonia; Controlled-release Agents; Stabilizing Agents; Suspending Agents; Tablet Binder; Viscosity-increasing Agents; ; 9000-40-2. UNII: V4716MY704. Chemical Name: Carob gum. Grade: Pharmceutical Excipients. Administration route: Oral. Dosage Form: oral tablet. Stability and Storage Conditions: The bulk material should be stored in a well-closed container in a cool, dry place. Ceratonia loses not more than 15% of its weight on drying. Source and Preparation: Ceratonia is a naturally occurring material obtained from the ground endosperms separated from the seeds of the locust bean tree, Ceratonia siliqua (Leguminosae). The tree is indigenous to southern Europe and the Mediterranean region. Applications: Ceratonia is a naturally occurring material generally used as a substitute for tragacanth or other similar gums. A ceratoni… CD Formulation
Ceritinib An anaplastic lymphoma kinase (ALK)-positive inhibitor used for the treatment of non-small cell lung cancer (NSCLC). It less potently inhibits IGF-1R, InsR, and STK22D and IC50 value is 8, 7, and 23 nM. LDK378 is also minimally effective against a panel of other kinases. In Sep 2016, Interim adverse events and efficacy data from phase III ASCEND-4 trial in non small cell lung cancer released by Novartis. In Oct 2016, efficacy data from the phase III ASCEND-3 and ASCEND-5 trial in non small cell lung cancer was presented. Uses: Antineoplastic agents. Synonyms: 5-Chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine, LDK-378, LDK378; LDK 378; Zykadia; NVP-LDK378-NX. Grades: ≥98%. CAS No. 1032900-25-6. Molecular formula: C28H36ClN5O3S. Mole weight: 558.14. BOC Sciences 9
Chlorphenesin Chlorphenesin is an antigen-associated immunosuppressant that inhibits IgE-mediated histamine release. Chlorphenesin is also used as an antimycotic agent. Group: Biochemicals. Alternative Names: (±)-p-Chlorphenesin; 3-(4-Chlorophenoxy)-1,2-propanediol; 3-(p-Chlorophenoxy)propane-1,2-diol; Adermykon; Chlorphenesin; Demykon; Elestab CPN; Gecophen; Glycerol α-p-chlorophenyl ether; Mycil; NSC 6401; p-Chlorophenyl glyceryl ether; p-Chlorophenyl-α-glyceryl ether; p-Chlorphenesin. Grades: Highly Purified. CAS No. 104-29-0. Pack Sizes: 2.5g, 25g, 50g, 100g. US Biological Life Sciences. USBiological 2
Worldwide
Cisapride hydrate Cisapride, also called as R51619, is a serotonin 5-HT4 receptor agonist used as a gastroprokinetic agent. Cisapride stimulates gastrointestinal motility, probably by facilitating acetylcholine release at the myenteric plexus. Synonyms: 4-amino-5-chloro-N-[(3S,4R)-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-yl]-2-methoxybenzamide; hydrate; Cisapridemonohydrate; 260779-88-2; cis-4-Amino-5-chloro-N-[1-[3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]-2-methoxybenxamidemonohydrate; CISAPRIDEMONOHYDRATE; 81098-60-4 (Cisapride free base); 189888-25-3 (Cisapride tartrate); 260779-88-2 (Cisapride hydrate). Grades: ≥99%. CAS No. 260779-88-2. Molecular formula: C23H29N3O4ClFH2O. Mole weight: 483.96. BOC Sciences 10
Clove Oil Clove Oil. Synonyms: Clove Bud Oil. CAS No. 8000-34-8. Product ID: PE-0414. Category: Flavoring agent. Product Keywords: Pharmaceutical Excipients; Excipients for Liquid Dosage Form; Clove Oil; Corrective Agents; Flavoring agent; /; 8000-34-8; 8000-34-8. UNII: 578389D6D0. Grade: Pharmceutical Excipients. Administration route: Oral; Dentistry (as toothpaste ingredient). Dosage Form: Toothpaste, elixir and suspension. Stability and Storage Conditions: Flammable, fire site release spicy stimulating smoke, easy to be oxidized, so should be sealed, shading, stored in a cool, dry place, away from the source of fire, heat and oxidant. Commonly used amount and the maximum amount: General dosage 3-1800mg/kg. Source and Preparation: An essential oil obtained by steam distillation from the dried flower buds of Eugenia caryophyllate or E. aromatica, a plant in the myrtle family. Its main components are eugenol (70%-90%), eugenol ethyl acetate (10%-15%), caryophyllene (5%-12%), methylamyl protanol, methylheptyl protanol, methylamyl ketone and ylenene, etc. Safety: This product is generally considered safe. CD Formulation
Copovidone Copovidone is a white to yellowish-white amorphous powder. It is typically spray-dried with a relatively fine particle size. It has a slight odor and a faint taste. CAS No. 25086-89-9. Product ID: PE-0467. Molecular formula: (C6H9NO)n. Mole weight: (C6H9NO)n?1000000. Category: Binder Excipients. Product Keywords: Pharmaceutical Excipients; Excipients for Solid Dosage Form; Copovidone; Binder Excipients; Binder Excipients; (C6H9NO)n; 25086-89-9; 25086-89-9. UNII: D9C330MD8B. Chemical Name: Acetic acid ethenyl ester, polymer with 1-ethenyl-2-pyrrolidinone. Grade: Pharmceutical Excipients. Administration route: Oral. Dosage Form: Oral tablets, oral film-coated tablets, sustained action. Stability and Storage Conditions: Copovidone is stable and should be stored in a well-closed container in a cool, dry place. Source and Preparation: Copovidone is manufactured by free-radical polymerization of vinylpyrrolidone and vinyl acetate in a ratio of 6 : 4. The synthesis is conducted in an organic solvent owing to the insolubility of vinyl acetate in water. Applications: Copovidone is used as a tablet binder, a film-former, and as part of the matrix material used in controlled-release formulations. In tableting, copovidone can be used as a binder for direct compression and as a binder in wet granulation. Copovidone is often added to coating solutions as a film-forming agent. It provides good adhesion, elasticity, and hardness, and c… CD Formulation
Cyclopentamine Hydrochloride Cyclopentamine is a sympathomimetic alkylamine that is classified as a vasoconstrictor. Cyclopentamine is a release agent of the catecholamine neurotransmitters norepinephrine (noradrenaline), epinephrine (adrenaline), and dopamine. Synonyms: N,α-Dimethylcyclopentaneethanamine Hydrochloride; N,α-Dimethylcyclopentaneethylamine Hydrochloride; Clopane Hydrochloride; Cyclonarol Hydrochloride; Cyclopentadrin Hydrochloride; Cyclopentadrine Hydrochloride; Cyclopentamin Hydrochloride; Cyklosal Hydrochloride; Cyklosan Hydrochloride; Sinos Hydrochloride. Grades: 95%. CAS No. 538-02-3. Molecular formula: C9H20ClN. Mole weight: 177.72. BOC Sciences 8
Diazoxide Diazoxide is a potassium channel activator that causes local relaxation in smooth muscle by increasing membrane permeability to potassium ions. The cellular release of potassium switches off voltage-gated calcium ion channels which inhibits the generation of an action potential. Uses: Antihypertensive agents. Synonyms: 7-Chloro-3-methyl-4H-1,2,4-benzothiadiazine 1,1-dioxide. Grades: 98% (TLC). CAS No. 364-98-7. Molecular formula: C8H7ClN2O2S. Mole weight: 230.7. BOC Sciences 9
Dimethyl sulfoxide Dimethyl sulfoxide (DMSO) is an aprotic solvent that can dissolve water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and has the ability to rapidly penetrate or enhance the penetration of other substances through biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity [1]. Low endotoxin, can be used in various biochemical experiments such as drug dissolution. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: DMSO. CAS No. 67-68-5. Pack Sizes: 100 mL; 200 mL; 500 mL. Product ID: HY-Y0320C. MedChemExpress MCE
Dimethyl sulfoxide, meets analytical specification of Ch.P. Dimethyl sulfoxide (DMSO), meets analytical specification of Ch.P. is an aprotic solvent that dissolves polar and non-polar compounds, including water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and can rapidly penetrate or enhance the penetration of other substances into biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity. Dimethyl sulfoxide also exhibits antifreeze and antibacterial properties [1] [2] [3]. MCE provides Dimethyl sulfoxide that complies with the inspection standards (Ch.P) of Part 4 of the Chinese Pharmacopoeia (2020 Edition). Amicrobic, low endotoxin, can be used in various biochemical experiments such as drug dissolution. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: DMSO, meets analytical specification of Ch.P. CAS No. 67-68-5. Pack Sizes: 10 mL; 100 mL; 200 mL; 500 mL. Product ID: HY-Y0320. MedChemExpress MCE
Dipotassium phosphate Dipotassium hydrogen phosphate is a potassium salt that is the dipotassium salt of phosphoric acid. It has a role as a buffer. It is a potassium salt and an inorganic phosphate. CAS No. 7758-11-4. Product ID: PE-0665. Molecular formula: K2HPO4. Category: Buffer agent. Product Keywords: Excipients for Sustained & Controlled Release Materials; Dipotassium phosphate; PE-0665; Buffer agent; K2HPO4; 7758-11-4. Standard: CP. Color: White. EC Number: 231-834-5. Physical State: Solid. Solubility: H2O: 1 M at 20 °C, clear, colorless. Storage: Store at +5°C to +30°C. Applications: Dipotassium phosphate as a food additive, dipotassium phosphate is used in imitation dairy creamers, dry powder beverages, mineral supplements, and starter cultures. It functions as an emulsifier, stabilizer and texturizer; it also is a buffering agent, and chelating agent especially for the calcium in milk products. Boiling Point: 340 °C. Density: 2,44 g/cm3. Product Description: Dipotassium phosphate as a food additive, dipotassium phosphate is used in imitation dairy creamers, dry powder beverages, mineral supplements, and starter cultures. It functions as an emulsifier, stabilizer and texturizer; it also is a buffering agent, and chelating agent especially for the calcium in milk products. CD Formulation
D-Val-Leu-Lys 4-nitroanilide dihydrochloride D-Val-Leu-Lys 4-nitroanilide dihydrochloride stands as a crucial substrate to gauge the efficiency of trypsin-like serine proteases. Proteolysis event leads to the release of a yellow colored product, whose quantification can be done at 405 nm. Its utility can be seen in trypsin activity detection and the evaluation of agents restricting trypsin-like proteases. Consistent usage of this product aids in experimental design and the analysis of diverse protease substrates. Synonyms: (S)-6-Amino-2-((S)-2-((R)-2-amino-3-methylbutanamido)-4-methylpentanamido)-N-(4-nitrophenyl)hexanamide dihydrochloride; H-D-Val-Leu-Lys-pNA 2HCl. CAS No. 62354-43-2. Molecular formula: C23H40Cl2N6O5. Mole weight: 551.5. BOC Sciences 9
EMERY® E 6216 2-ethylhexyl palmitate. Uses: Bio-diluent, solvent or plasticizer, cleaning and stripping products, plastic additive, metal working fluid, release agent, emollient and dispersing additive, replacement for mineral, vegetable and selected silicone oils. Group: Fatty acid ester. Alternative Name: Dioctyl palmitate, 2-EH palmitate. Grade: Technical. Pack Sizes: Drums, Bulk Liquid (Truck & Rail). Emery Oleochemicals
EMERY® E 6217 2-ethylhexyl tallowate. Uses: Bio-diluent, solvent or plasticizer, cleaning and stripping products, plastic additive, metal working fluid, release agent, replacement for mineral, vegetable and selected silicone oils. Group: Fatty acid ester. Alternative Name: Dioctyl tallowate, 2-EH tallowate. Grade: Technical. Pack Sizes: Drums, Bulk Liquid (Truck & Rail). Emery Oleochemicals
EMERY® E 6218 2-ethylhexyl stearate. Uses: Diluent in lipophilic systems, cosmetic emollient and dispersant, plastic additive, industrial lubricant, release agent, replacement for mineral, vegetable and selected silicone oils, pigment binding and dispersing co-agent. Group: Fatty acid ester. Alternative Name: Dioctyl stearate,2-EH stearate. Grade: Technical. Pack Sizes: Drums, Bulk Liquid (Truck & Rail). Emery Oleochemicals
EMERY® E 6219 2-ethylhexyl oleate. Uses: Bio-diluent, solvent or plasticizer, cleaning and stripping products, fragrance fixative, metal working fluid, release agent, replacement for mineral, vegetable and selected silicone oils. Group: Fatty acid ester. Alternative Name: Dioctyl oleate,2-EH oleate. Grade: Technical.. Pack Sizes: Drums, Bulk Liquid (Truck & Rail). Emery Oleochemicals
EMERY® E 6919 Trimethylolpropane oleate. Uses: Bio-diluent, solvent or plasticizer, cleaning and stripping products, plastic additive, metal working fluid, release agent, replacement for mineral, vegetable and selected silicone oils. Group: Fatty acid ester. Alternative Name: TMP oleate. Grade: Technical. Pack Sizes: Drums, Bulk Liquid (Truck & Rail). Emery Oleochemicals
Endo-1,4-β-mannanase Endo-1,4-β-mannanase is an important catalytic agent that randomly cleave the β-1,4-linkage in the mannan backbone and release short β-1,4-mannooligosaccharides and mannose [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 37288-54-3. Pack Sizes: 10 g; 25 g; 50 g; 100 g. Product ID: HY-E70110. MedChemExpress MCE
Erastin Erastin is an antitumor agent selective for tumor cells bearing oncogenic RAS (i.e. HRAS, KRAS). Erastin produces non-apoptotic tumor cell death by altering mitochondrial voltage-dependent anion channel (VDAC) gating allowing cations to enter mitochondria and leading to release of oxidative species causing oxidative cell death. Erastin blocks and reverses mitochondrial depolarization after microtubule destabilizers in intact cells and antagonized tubulin-induced VDAC blockage in planar bilayers. Reversal of tubulin-VDAC interaction by erastin antagonizes Warburg metabolism and restores oxidative mitochondrial metabolism. Synonyms: Erastin. Grades: 0.98. CAS No. 571203-78-6. Molecular formula: C30H31ClN4O4. Mole weight: 547.04454. BOC Sciences 8
Ethoxy Functional Silicone Resin It is used in silicone polyester copolymer, release agent, filler treatment (hydrophobic surface). Group: Silicone. CAS No. 67923-21-1. Appearance: Opaque, straw color liquid. Catalog: ACM67923211. Alfa Chemistry. 2
Ethyl Cellulose Ethyl Cellulose is a water-insoluble polymer that is derived from cellulose. It is widely used in various industries such as pharmaceuticals, food additives, coatings, and cosmetics due to its excellent film-forming and binding properties. Ethyl cellulose is formed by the reaction of cellulose with ethyl chloride, which results in the replacement of hydroxyl groups in the cellulose molecule with ethyl groups. In the cosmetics industry, Ethyl Cellulose is used as a binding agent in hairsprays, gels, and other hair styling products to improve their hold and durability. Uses: 1. ethyl cellulose is used as an inactive ingredient in pharmaceutical products such as tablets and capsules. 2. it is used as a coating for controlled release of drugs in the gastrointestinal tract. 3. ethyl cellulose is used as a binder in food products such as chewing gum, ice cream, and sauces. 4. it is used as a thickener in personal care products such as lotions, creams, and sunscreens. 5. e. Group: Natural polymers and biopolymerspolysaccharidepolymers. Alternative Names: Cellulose, ethyl ether. CAS No. 9004-57-3. Product ID: (2R,3R,4S,5S,6R)-5-[(2S,3R,4S,5S,6R)-4,6-bis(ethoxymethyl)-3,5-dihydroxyoxan-2-yl]oxy-3-ethoxy-6-(hydroxymethyl)oxane-2,4-diol. Molecular formula: 454.5. Mole weight: C20H38O11. CCOCC1C (C (OC (C1O)OC2C (OC (C (C2O)OCC)O)CO)COCC)O. InChI=1S/C19H36O11/c1-4-25-8-10-13 (21)12 (9-26-5-2)29-19 (14 (10)22)30-16-11 (7-20)28-18 (24)… Alfa Chemistry Materials 5
Etofibrate Etofibrate is a fibrate. It is a combination of clofibrate and niacin, linked together by an ester bond. In the body, clofibrate and niacin separate and are released gradually, in a manner similar to controlled-release formulations. Uses: Anticholesteremic agents. Synonyms: ethofibrate; Etofibrato; 3-Pyridinecarboxylic acid, 2-[2-(4-chlorophenoxy)-2-methyl-1-oxopropoxy]ethyl ester; Lipo-Merz; Tricerol. Grades: >98%. CAS No. 31637-97-5. Molecular formula: C18H18ClNO5. Mole weight: 363.79. BOC Sciences 11
Forskolin (Coleus forskohlii) The major cell-permeable diterpene isolated from the Indian plant Coleus forskohlii. At low doses, it acts as a positive inotropic agent. At higher doses, it serves as a hypotensive and vasodilatory agent due to its actions as a smooth muscle relaxant. No major side effects are observed at effective doses. Forskolins pharmacological activities are due to its activation of adenylate cyclase (EC50 = 4uM), resulting in increased cAMP levels. The exact mechanism of forskolins positive inotropic effect is unknown but may be related to a cAMP-dependent increase in Na+ permeability that results in indirect augmentation of Ca2+ release. Inhibits MAP kinase in rat renal mesangial cells (IC50 = 25uM). Also acts as a Hh pathway antagonist. Shown to inhibit apoptosis in cerebellar granule cells and to induce apoptosis in resting human B lymphocytes. Group: Biochemicals. Grades: Highly Purified. CAS No. 66575-29-9. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 4
Worldwide
Forskolin, Coleus forskohlii (7b-Acetoxy-8,13-epoxy-1α,6 β,9α-trihydroxy-labd-14-en-11-one, Colforsin) The major cell-permeable diterpene isolated from the Indian plant Coleus forskohlii. At low doses, it acts as a positive inotropic agent. At higher doses, it serves as a hypotensive and vasodilatory agent due to its actions as a smooth muscle relaxant. No major side effects are observed at effective doses. Forskolins pharmacological activities are due to its activation of adenylate cyclase (EC50=4uM), resulting in increased cAMP levels. The exact mechanism of forskolins positive inotropic effect is unknown but may be related to a cAMP-dependent increase in Na+ permeability that results in indirect augmentation of Ca2+ release. Inhibits MAP kinase in rat renal mesangial cells (IC50= 25uM). Also acts as a Hh pathway antagonist. Shown to inhibit apoptosis in cerebellar granule cells and to induce apoptosis in resting human B lymphocytes. Group: Biochemicals. Grades: Highly Purified. CAS No. 66575-29-9. Pack Sizes: 10mg, 25mg. Molecular Formula: C??H??O?. US Biological Life Sciences. USBiological 4
Worldwide
FR-A 19 FR-A 19 is a Histamine H2 receptor agonist with potent anti-allergic properties. It can inhibit IgE-mediated human basophil histamine release in a nanomolar range. Uses: Anti-allergic agent. Synonyms: FR-A 19; FR-A-19; FRA19; N,N-bis(3-(4-fluorophenyl)propyl)-N'-(3-(1H-imidazol-4-yl)propyl)-Guanidine trihydrochloride. Grades: 98%. CAS No. 141099-46-9. Molecular formula: C25H34Cl3F2N5. Mole weight: 548.93. BOC Sciences 10
Glycerol monostearate Glycerol monostearate, commonly known as GMS, is the glycerol ester of stearic acid. It is commonly used as an emulsifier in foods. Glyceryl monostearate is a natural product found in Aristolochia cucurbitifolia, Lobelia longisepala, and other organisms with data available. Uses: Used as a pharmaceutical aid; permitted for use as an inert ingredient in non-food pesticide products; used as an emulsifier, firming agent, flavor enhancer, lubricant or release agent, masticatory substance, and texturizer for foods; glycerol monostearate, commonly known as gms, is an organic molecule used as an emulsifier. Group: Polymer/macromolecule. Alternative Names: Glyceryl monostearate 123-94-4 Monostearin 31566-31-1 GLYCEROL MONOSTEARATE Glyceryl stearate 1-Stearoyl-rac-glycerol Tegin 1-MONOSTEARIN 2,3-dihydroxypropyl octadecanoate Glycerin 1-monostearate Glycerol 1-monostearate Stearin, 1-mono- Stearic acid 1-monoglyceride 1-Monostearoylglycerol Octadecanoic acid, 2,3-dihydroxypropyl ester 1-Glyceryl stearate Glycerin 1-stearate Glycerol 1-stearate. CAS No. 31566-31-1. Molecular formula: C21H42O4. Mole weight: 358.6 g/mol. IUPACName: 2,3-dihydroxypropyl octadecanoate. Canonical SMILES: CCCCCCCCCCCCCCCCCC(=O)OCC(CO)O. Density: 0.910 (25°C). Catalog: ACM31566311. Alfa Chemistry.
Glyceryl Monooleate Glyceryl Monooleate. Synonyms: Glycerol Mono-oleate(BP); Aldo MO; Atlas G-695; Capmul GMO; glycerol-1-oleate; glyceroli mono-oleas; glyceryl mono-oleate; HallStar GMO; Imwitor 948; Kessco GMO; Ligalub; monolein; Monomuls 90-O18; mono-olein; a-mono-olein glycerol; Peceol; Priolube 1408; Stepan GMO; Tegin. CAS No. 25496-72-4. Product ID: PE-0572. Molecular formula: C21H40O4. Mole weight: 356.55. Category: Bioadhesive Material; Emollient; Emulsifier; Emulsion Stabilizer; Gelling Agents; Nonionic Surfactant; Continuous Release Agents. Product Keywords: Stabilizers; Emulsifier Excipients; Surfactant Excipients; ; PE-0572; Glyceryl Monooleate; Bioadhesive Material; Emollient; Emulsifier; Emulsion Stabilizer; Gelling Agents; Nonionic Surfactant; Continuous Release Agents; C21H40O4; 25496-72-4. UNII: C4YAD5F5G6. Chemical Name: 9-Octadecenoic acid (Z), monoester with 1, 2, 3-propanetriol. Grade: Pharmceutical Excipients. Administration route: Oral; Topical. Dosage Form: Soluble film. Stability and Storage Conditions: Monoolein should be stored in an airtight container in a cool, dry place away from light. Commonly used amount and the maximum amount: When used as emulsifier or cosolvent in topical preparations, the maximum dosage is generally 5mg/g. Source and Preparation: Monooleic glycerides are produced by the ester of fatty acids, mainly oleic acids, with glycerides. Since fatty acids are not pure substances but mixt… CD Formulation
Glyceryl Monostearate While the names glyceryl monostearate and mono- and diglycerides are used for a variety of esters of long-chain fatty acids, the esters fall into two distinct grades: 40-55 percent monoglycerides The PhEur describes glyceryl monostearate 40-55 as a mixture of monoacylglycerols, mostly monostearoylglycerol, together with quantities of di- and triacylglycerols. It contains 40-55% of monoacylglycerols, 30-45% of diacylglycerols, and 5-15% of triacylglycerols. Synonyms: Capmul GMS-50; Cutina GMS; 2, 3-dihydroxypropyl octadecanoate; Geleol; glycerine monostearate; glycerin monostearate; glycerol monostearate; glyceroli monostearas; glycerol stearate; glyceryl stearate; GMS; HallStar GMS; Imwitor 191; Imwitor 900; Kessco GMS; Lipo GMS; monoester with 1, 2, 3-propanetriol; monostearin; Myvaplex 600P; Myvatex; 1, 2, 3-propanetriol octadecanoate; Protachem GMS-450; Ri. CAS No. 31566-31-1. Product ID: PE-0518. Molecular formula: C21H42O4. Mole weight: 358.6. Category: Emollient; Emulsifying Agents; Solubilizing Agents; Stabilizing Agents; Sustained-release Agents; Tablet and Capsule Lubricant. Product Keywords: Emulsifier Excipients; Solubilizer Excipients; PE-0518; Glyceryl Monostearate; Emollient; Emulsifying Agents; Solubilizing Agents; Stabilizing Agents; Sustained-release Agents; Tablet and Capsule Lubricant; C21H42O4; 31566-31-1. UNII: NA. Chemical Name: Octadecanoic acid, monoester with 1, 2, 3-propanetriol. Gra… CD Formulation
Guar Gum Guar Gum all grades from Mexico. Uses: Food industry:it is used as a thickener, stabilizer, and suspending agent in products such as ice cream, sauces, dressings, baked goods, beverages, and dairy products. - pharmaceutical industry: it is used in the manufacture of tablets and capsules as a compression agent and as a coating agent to improve controlled release. -cosmetic industry: it is used in personal care products, such as creams, lotions, and shampoos, as a thickening and stabilizing agent. - paper industry: it is used in paper and board manufacturing to improve water retention, increase tear resistance and improve sheet formation. -textile industry: it is used in the textile printing process as a thickening agent to improve the viscosity and adhesion of dyes. -oil well drilling: it is used as an additive in drilling fluids to control viscosity and prevent fluid loss. CAS No. 900-30-0. Pack Sizes: Bags, Supersacks. TZ GROUP INC
Hemicholinium 3 Hemicholinium 3 is a competitive inhibitor of the high affinity choline transporter (HACU) with a K i value of 25 nM. Hemicholinium 3, a neuromuscular blocking agent which inhibits the synthesis and the release of acetylcholine (ACh) [1]. Hemicholinium 3 inhibits the Epibatidine-evoked contraction and [ 3 H]acetylcholine release with IC50s of 897 nM and 693 nM, respectively [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Hemicholinium dibromide. CAS No. 312-45-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B2152. MedChemExpress MCE
Hilose CCS (50μ) Hilose CCS (50μ). Fine particle size, croscarmellose sodium is an internally cross-linked sodium carboxymethyl cellulose. It is a white, odorless, and tasteless powder recommended for pharmaceutical and dietary supplement applications. Dosage Form: Capsule, Orally Disintegrating Tablet, Tablet. Functionality: Cellulose Filling, Disintegrant, Dissolution Accelerator, Rapid Release Agent. Process: Direct Compression, Dry Granulation, Wet Granulation. Particle Size: 50 microns. Sigachi US Inc
Sigachi US Inc
Hilose CCS (90μ) Hilose CCS (90μ). Coarse particle size, croscarmellose sodium is an internally cross-linked sodium carboxymethyl cellulose. It is a white, odorless, and tasteless powder recommended for pharmaceutical and dietary supplement applications. Dosage Form: Capsule, Orally Disintegrating Tablet, Tablet. Functionality: Cellulose Filling, Disintegrant, Dissolution Accelerator, Rapid Release Agent. Process: Direct Compression, Dry Granulation, Wet Granulation. Particle Size: 90 microns. Sigachi US Inc
Sigachi US Inc
Hydrogenated Castor Oil Hydrogenated Castor Oil can be used as stiffening agent, an extended release agent, tablet and capsule lubricant. Synonyms: MPA 1075;Thixin;WNN 1;T 20SF;Lubliwax. CAS No. 8001-78-3. BOC Sciences
Hymetellose328 Hymetellose328. Synonyms: Methylhydroxyethylcellulose; Cellulose; 2-hydroxyethyl methyl ether; HEMC; Tyopur MH. CAS No. 9032-42-2. Product ID: PE-0540. Molecular formula: C2H6O2·xCH4O·x. Category: Pore-forming Agents; Coating Agents; Thickener; Suspending Agents; Dispersing Agents; Binding Agents; Emulsifier; Film-forming Agents; Water-retaining Agents. Product Keywords: Excipients for Liquid Dosage Form; Emulsifier Excipients; PE-0540; Hymetellose328; Pore-forming Agents; Coating Agents; Thickener; Suspending Agents; Dispersing Agents; Binding Agents; Emulsifier; Film-forming Agents; Water-retaining Agents; C2H6O2·xCH4O·x; 9032-42-2. UNII: 0MGW7Q3QG4. Chemical Name: Hydroymethylmethylecellulose. Grade: Pharmceutical Excipients. Administration route: Oral, optical. Dosage Form: Oral suspensions, tablets and topical formulations. Stability and Storage Conditions: Hydroxymethylcellulose is hygroscopic and should be stored in a cool, dry place. Applications: 1.Pharmacy As a hydrophilic gel matrix material, porogen, and coating agent for the preparation of sustained-release preparations. It can also be used as a thickening, suspending, dispersing, binding, emulsifying, film-forming, and water-retaining agent for preparations. 2. Food processing can also be used as, adhesive, emulsifying, film-forming, thickening, suspending, dispersing, water-retaining agent, etc. 3. In the daily chemical industry, it is used as an addi… CD Formulation
Hypromellose Hypromellose. Synonyms: Benecel MHPC; E464; hydroxypropyl methylcellulose; HPMC; hypromellosum; Methocel; methylcellulose propylene glycol ether; methyl hydroxypropylcellulose; Metolose; MHPC; Pharmacoat; Tylopur; Tylose MO. CAS No. 9004-65-3. Product ID: PE-0206. Category: Bioadhesive Material; Coating Agents; Controlled-release Agents; dispersing Agents; Emulsifying Agents; Emulsion Stabilizer; extended-release Agents; Film-forming Agents; foaming Agents; Granulation Aid; modified-release Agents; mucoadhesive. Product Keywords: Coating Systems Excipients; Emulsifier Excipients; Suspending Agents; ; PE-0206; Hypromellose; Bioadhesive Material; Coating Agents; Controlled-release Agents; dispersing Agents; Emulsifying Agents; Emulsion Stabilizer; extended-release Agents; Film-forming Agents; foaming Agents; Granulation Aid; modified-release Agents; mucoadhesive; 9004-65-3. UNII: B1QE5P712K. Chemical Name: Cellulose hydroxypropyl methyl ether. Grade: Pharmceutical Excipients. Administration route: Ophthalmic and nasal; oral. Dosage Form: Ophthalmic and nasal preparations; oral capsules, suspensions, syrups, and tablets. Stability and Storage Conditions: Hypromellose powder is a stable material, although it is hygroscopic after drying. Solutions are stable at pH 3-11. Hypromellose undergoes a reversible sol-gel transformation upon heating and cooling, respectively. The gelation temperature is 50-90°C, depending upon the g… CD Formulation

Would you like to list your products on USA Chemical Suppliers?

Our database is helping our users find suppliers everyday.

Add Your Products