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2-Hydroxy-4,6-dimethoxybenzoic acid is a reagent used in the synthesis of rac Zearalenone-d6 (Z270502). rac Zearalenone-d6 s an estrogenic mycotoxin produced by Fusarium fungi commonly found in grains. One of a group of compounds known as resorcylicacid lactones. Group: Biochemicals. Grades: Highly Purified. CAS No. 3187-19-7. Pack Sizes: 100mg, 250mg. Molecular Formula: C9H10O5, Molecular Weight: 198.05. US Biological Life Sciences.
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3,5-Dihydroxybenzoic acid
3,5-DHBA is a selective agonist of hydroxycarboxylic acid receptor 1 (HCA1/GPR81) (EC50 ~150 μM). It inhibits lipolysis in wild-type mouse adipocytes. 3,5-DHBA can be used as a biomarker of whole grain wheat and rye. Synonyms: Benzoic acid, 3,5-dihydroxy-; α-Resorcylicacid; 5-Carboxyresorcinol; NSC 22948. Grades: ≥95%. CAS No. 99-10-5. Molecular formula: C7H6O4. Mole weight: 154.12.
3,5-Dihydroxybenzoic acid
3,5-Dihydroxybenzoic acid. Group: Biochemicals. Alternative Names: a-Resorcylicacid; 5-Carboxyresorcinol; NSC 22948. Grades: Highly Purified. CAS No. 99-10-5. Pack Sizes: 100g, 250g, 500g, 1Kg, 2Kg. Molecular Formula: C7H6O4. US Biological Life Sciences.
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3,5-Dihydroxybenzoic Acid 3-O-Sulfate Sodium Salt
3,5-Dihydroxybenzoic Acid 3-O-Sulfate is a possible metabolite of alkylresorcinol in humans. Group: Biochemicals. Alternative Names: α-ResorcylicAcid 3-O-Sulfate Sodium; 5-Carboxyresorcinol 3-O-Sulfate Sodium. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
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3-Hydroxymitorubrin
3-Hydroxymitorubrin is a mitorubrin derivative. Mitorubrin is a unique subgroup of azaphenanthrene isolated from various fungal species. Synonyms: Mitorubrinol; Benzoic acid, 2,4-dihydroxy-6-methyl-, 7,8-dihydro-3-(3-hydroxy-1-propenyl)-7-methyl-6,8-dioxo-6H-2-benzopyran-7-yl ester, [R-(E)]-; β-Resorcylicacid, 6-methyl-, 7-ester with 7-hydroxy-3-(3-hydroxypropenyl)-7-methyl-6H-2-benzopyran-6,8(7H)-dione (7CI,8CI); 6H-2-Benzopyran-6,8(7H)-dione, 7-hydroxy-3-(3-hydroxypropenyl)-7-methyl-, 7-(6-methyl-β-resorcylate) (8CI). CAS No. 3215-47-2. Molecular formula: C21H18O8. Mole weight: 398.36.
4-O-Demethylbarbatic acid
4-O-Demethylbarbatic acid is an inhibitor of leukotriene B4 (LTB4). Synonyms: β-Resorcylicacid, 3,6-dimethyl-, 4-(3,6-dimethyl-β-resorcylate) (8CI); 4-Carboxy-3-hydroxy-2,5-dimethylphenyl 2,4-dihydroxy-3,6-dimethylbenzoate; Barbatic acid, 4-O-demethyl-. CAS No. 20372-89-8. Molecular formula: C18H18O7. Mole weight: 346.33.
4-O-Methylgyrophoric acid
4-O-Methylgyrophoric acidis an analog of Gyrophoric acid. Gyrophoric acid is a depside that can be found in the lichen Cryptothecia rubrocincta and in Xanthoparmelia pokomyi. Synonyms: Amidepsine K; 2,6-Cresotic acid, 4-methoxy-, 4-ester with 6-methyl-β-resorcylicacid, 4-ester with 6-methyl-β-resorcylicacid (8CI); β-Resorcylicacid, 6-methyl-, 4-(6-methyl-β-resorcylate) 4-(4-methoxy-2,6-cresotate) (8CI). CAS No. 23437-51-6. Molecular formula: C25H22O10. Mole weight: 482.44.
4-O-Methylhyperolivetoric acid
4-O-Methylhyperolivetoric acid is a lichen depside. Synonyms: β-Resorcylicacid, 6-heptyl-, 4-[2-hydroxy-6-(2-oxoheptyl)-p-anisate] (8CI). CAS No. 21251-07-0. Molecular formula: C29H38O8. Mole weight: 514.61.
5-Bromo-2,4-dihydroxybenzoic acid
5-Bromo-2,4-dihydroxybenzoic acid. Group: Biochemicals. Alternative Names: 2 4-Dihydroxy-5-bromobenzoic acid; 5-Bromo-b-resorcylicacid. Grades: Highly Purified. CAS No. 7355-22-8. Pack Sizes: 10g, 25g, 50g, 100g, 250g. US Biological Life Sciences.
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(5E)-7-Oxozeaenol
(5E)-7-Oxozeaenol, a resorcylicacid lactone isolated from the fungus MSX 63935 and Drechslera portulacae, has enzyme inhibitory effect and anticancer activities. Synonyms: Oxozeaenol, (5E)-7-; (3S,5E,8S,9S,11E)-3,4,9,10-tetrahydro-8,9,16-trihydroxy-14-methoxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione; LL-Z 1640-2; Cochliomycin F; (2E,5S,6S,8E,11S)-5,6,15-trihydroxy-17-methoxy-11-methyl-12-oxabicyclo[12.4.0]octadeca-1(18),2,8,14,16-pentaene-7,13-dione. Grades: ≥95% by HPLC. CAS No. 1198574-97-8. Molecular formula: C19H22O7. Mole weight: 362.37.
alpha-Zearalenol-[d5]
α-Zearalenol-[d5] is a labelled impurity of Zearalenol. Zearalenol, a resorcylicacid lactones derivative, could be produced by Fusarium fungi in grains and has been found to be an environmental contaminant. Synonyms: α-Zearalenol-d5; (E)-(7S,11R)-2,4,11-Trihydroxy-7-methyl-7,8,9,10,11,12,13,14-octahydro-10,10,11,12,12-D5-6-oxa-benzocyclotetradecen-5-one; (-)-α-Zearalenol-d5; Zearalenol-d5; trans-Zearalenol-d5; (3S,7R,11E)-3,4,5,6,7,8,9,10-Octahydro-7,14,16-trihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1-one-d5. Grades: 95% by HPLC; 98% atom D. CAS No. 36455-72-8. Molecular formula: C18H19D5O5. Mole weight: 325.41.
Antibiotic LL Z1640-2 (Antibiotic C292, Antibiotic L 783278)
Antibiotic LL Z1640-2 a cis-enone resorcylicacid lactone first reported in 1978 and later rediscovered as an irreversible and highly selective TAK 1 inhibitor. TAK1 is a MAPKKK involved in the p38 signalling cascade for pro-inflammation signals such as cytokines. LL Z1640-2 effectively prevents inflammation in an animal models. Group: Biochemicals. Alternative Names: Antibiotic C292, Antibiotic L 783278. Grades: Highly Purified. CAS No. 66018-38-0. Pack Sizes: 1mg. US Biological Life Sciences.
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Antibiotic LL Z1640-4 (Zeaenol)
Antibiotic LL Z1640-4 is a cis-enol resorcylicacid lactone first reported in 1978 exhibiting both antiviral and antiprotozoan activity. More recently, antibiotic LL Z1640-2 containing the essential cis-enone system that selectively inhibits TAK 1 has gained literature focus. With its inactive cis-enol, Antibiotic LL Z1640-4 is an ideal negative control to help dissect the selectivity of the MAP kinases. Group: Biochemicals. Alternative Names: Zeaenol. Grades: Highly Purified. CAS No. 66018-41-5. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Aphthosin
Aphthosin is a tetrapeptide glycoside isolated from Peltigera aphthosa (L.) Willd. Synonyms: 2,6-Cresotic acid, 4-methoxy-, 4-ester with 6-methyl-β-resorcylicacid, 4-ester with 6-methyl-β-resorcylicacid, 4-ester with methyl 6-methyl-β-resorcylate (8CI). CAS No. 31449-13-5. Molecular formula: C34H30O13. Mole weight: 646.59.
Bergenin
A herbal remedy with antioxidant, antimicrobial and antiinflammatory properties. Group: Biochemicals. Alternative Names: (2R,3S,4S,4aR,10bS)-3,4,4a,10b-Tetrahydro-3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxy-pyrano[3,2-c][2]benzopyran-6(2H)-one; 4-Methoxy-2-[tetrahydro-3,4,5-trihydroxy-6-(hydroxymethyl)pyran-2-yl]-α-resorcylicAcid δ-Lactone; Ai Cha Su; Ardisic Acid B; Bergenit; Corylopsin; Cuscutin; NSC 661749; Peltophorin; Vakerin. Grades: Highly Purified. CAS No. 477-90-7. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. US Biological Life Sciences.
Worldwide
Divaricatic acid
Divaricatic acid, a secondary metabolite produced by lichens of the genus Ramalina, has molluscicidal and antiparasitic activities. Synonyms: Divaricatic acid (Evernia); NSC 646003; Benzoic acid, 2-hydroxy-4-((2-hydroxy-4-methoxy-6-propylbenzoyl)oxy)-6-propyl-; divericatic acid; Divaricatsaeure; p-Anisic acid, 2-hydroxy-6-propyl-, 4-ester with 6-propyl-β-resorcylicacid; β-resorcylicacid, 6-propyl-, 4-(2-hydroxy-6-propyl-p-Anisate). CAS No. 491-62-3. Molecular formula: C21H24O7. Mole weight: 388.41.
Hypothemycin
Hypothemycin, a resorcylicacid lactone antibiotic, was identified as active in a screen for inhibitors of T cell activation. It was found to inhibit the proliferation of mouse and human T cells stimulated with anti-CD3 mAb + PMA and of human PBMC stimulated with anti-CD3 mAb alone. This inhibition was partially reversed by exogenous IL-2 indicating that it is not due to non-specific toxicity. Hypothemycin potently suppressed the production of IL-2 (IC50: 9 nM) but affected IL-2-induced proliferation to a lesser extent (IC50: 194 nM). Hypothemycin also inhibited IL-6, IL-10, IFN-gamma and TNF-alpha production. By contrast, it markedly enhanced the production of IL-4, IL-5 and IL-13. These effects were seen both at the mRNA and protein secretion levels. Analysis of the effect of hypothemycin on CD69 induction suggested that it disrupts calcineurin-independent rather than calcineurin-dependent signaling. Furthermore, hypothemycin was able to inhibit the phosphorylation of ERK1/2 induced by PMA treatment of T cells. Therefore, hypothemycin represents an inhibitor of T cell activation with a novel mode of action and unique modulatory activity on cytokine production. Synonyms: Hypothemycin. CAS No. 76958-67-3. Molecular formula: C19H22O8. Mole weight: 378.38.
LL Z1640-4
A cis-enol resorcylicacid lactone exhibiting antiviral and antiprotozoan activity. Synonyms: Zeaenol. Grades: >99% by HPLC. CAS No. 66018-41-5. Molecular formula: C19H24O7. Mole weight: 364.39.
Methyl β-Resorcylate
Methyl β-Resorcylate. Group: Biochemicals. Alternative Names: 2,4-Dihydroxybenzoic Acid Methyl Ester; Methyl 2,4-Dihydroxybenzoate; β-ResorcylicAcid Methyl Ester. Grades: Highly Purified. CAS No. 2150-47-2. Pack Sizes: 10g. Molecular Formula: C8H8O4, Molecular Weight: 168.15. US Biological Life Sciences.
Mitorubrin is a metabolite synthesized by phytotoxic fungi. Synonyms: (-)-Mitorubrin; β-Resorcylicacid, 6-methyl-, ester with 7-hydroxy-7-methyl-3-propenyl-6H-2-benzopyran-6,8(7H)-dione (7CI,8CI). CAS No. 3403-71-2. Molecular formula: C21H18O7. Mole weight: 382.36.
Olivetolic Acid
Olivetolic Acid is a precursor in the synthesis of primin and tetrahydrocannabinol. Group: Biochemicals. Alternative Names: 2-Amyl-4,6-dihydroxy-benzoic acid; Olivetolic Acid; 6-Pentyl- β-resorcylicAcid; 2,4-Dihydroxy-6-pentylbenzoic Acid; Allazetolcarboxylic Acid; Olivetolcarboxylic Acid. Grades: Highly Purified. CAS No. 491-72-5. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C??H??O?, Molecular Weight: 224.25. US Biological Life Sciences.
Worldwide
Olivetoric acid
It occurs in lichens and forms a purplish red color with a solution of ferric chloride. Mainly used in chemical research. Synonyms: Benzoic acid, 2,4-dihydroxy-6-(2-oxoheptyl)-, 4-carboxy-3-hydroxy-5-pentylphenyl ester; beta-Resorcylicacid, 6-(2-oxoheptyl)-, 4-carboxy-3-hydroxy-5-pentylphenyl ester; 4-[2-(2-Oxoheptyl)-4,6-dihydroxybenzoyloxy]-6-pentylsalicylic acid; 2,4-Dihydroxy-6-(2-oxoheptyl)benzoic acid 4-carboxy-3-hydroxy-5-pentylphenyl ester; 4,6-Dioxy-2-(β-oxo-n-heptyl)-benzoesaeure-(5-oxy-4-carboxy-3-n-amyl-phenylester); β-Resorcylicacid, 6-(2-oxoheptyl)-, 4-carboxy-3-hydroxy-5-pentylphenyl ester. Grades: 99%. CAS No. 491-47-4. Molecular formula: C26H32O8. Mole weight: 472.53.
Phenarctin is obtained from Nephroma arcticum. Synonyms: 3-Hydroxy-4-(methoxycarbonyl)-2,5,6-trimethylphenyl 3,5-diformyl-2,4-dihydroxy-6-methylbenzoate; β-Resorcylicacid, 3,5-diformyl-6-methyl-, 4-ester with methyl 3,5,6-trimethyl-β-resorcylate (8CI). CAS No. 27839-39-0. Molecular formula: C21H20O9. Mole weight: 416.38.
rac Zearalenone-d6
Estrogenic mycotoxin produced by Fusarium fungi commonly found in grains. One of a group of compounds known as resorcylicacid lactones. Group: Biochemicals. Alternative Names: (+/-)-3,4,5,6,9,10-Hexahydro-14,16-dihydroxy-3-methyl-. Grades: Highly Purified. CAS No. 1185236-04-7. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Radicicol (Monorden)
Radicicol is a resorcylicacid lactone produced by several fungal species that exhibits broad spectrum antifungal and antitumor activity. Radicicol has been the subject of extensive investigation and been shown to inhibit protein tyrosine kinase, induce the differentiation of HL-60 cells into macrophages, block cell cycle at G1 and G2, suppress NIH 3T3 cell transformation by diverse oncogenes such as src, ras and mos and also suppress the expression of mitogen-inducible cyclooxygenase-2. As a cell differentiation modulator, radicicol has anti-angiogenic activity in vivo, inhibiting the proliferation of plasminogen activator production by vascular endothelial cells. Group: Biochemicals. Alternative Names: Monorden. Grades: Highly Purified. CAS No. 12772-57-5. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Zearalenone-14-O-β-glucoside
Zearalenone-14-O-β-glucoside is an impurity of Zearalenol. Zearalenol, a resorcylicacid lactones derivative, could be produced by Fusarium fungi in grains and has been found to be an environmental contaminant. Synonyms: (3S)-16-Hydroxy-3-methyl-3,4,5,6,7,8,9,10-octahydro-1H-2-benzoxacyclotetradecine-1,7-dione-14-O-β-D-glucopyranoside. Molecular formula: C24H32O10. Mole weight: 480.5.
2',4'-Dihydroxy-2-benzoylbenzoic Acid
A by-product of Fluorescein. Group: Biochemicals. Alternative Names: 2- (2, 4-Dihydroxybenzoyl) benzoic Acid; o- β-Resorcyloylbenzoic Acid; DHBBA. Grades: Highly Purified. CAS No. 2513-33-9. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
3,5-Dihydroxybenzoic Acid Methyl Ester
The methyl ester of 3,5-Dihydroxybenzoic Acid with potential antifeedant activity for pine weevil, Hylobius abietis. Group: Biochemicals. Alternative Names: α-Resorcinol Carboxylic Acid Methyl Ester; 3,5-Dihydroxy Methyl Benzoate; 3,5-Dihydroxybenzoic Acid Methyl Ester; Methyl 3,5-dihydroxybenzoate; Methyl α-Resorcylate; NSC 146458. Grades: Highly Purified. CAS No. 2150-44-9. Pack Sizes: 5g. US Biological Life Sciences.
Worldwide
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