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| Product | Description | |
|---|---|---|
| RNA helicase | RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. Some helicases unwind DNA as well as RNA. May be identical with EC 3.6.4.12 (DNA helicase). Group: Enzymes. Synonyms: CSFV NS3 helicase; DBP2; DbpA; DDX17; DDX25; DDX3; DDX3X; DDX3Y; DDX4; DDX5; DEAD-box protein DED1; DEAD-box RNA helicase; DEAH-box protein 2; DEAH-box RNA helicase; DED1; Dex(H/D) RNA helicase; EhDEAD1; EhDEAD1 RNA helicase; eIF4A helicase; KOKV helicase; Mtr4p; nonstructural protein 3 helicase; NPH-II; RHA; RNA helicase A; RNA helicase DDX3; RNA helicase Hera; RNA-dependent ATPase; TGBp1 NTPase/helicase domain; VRH1; GRTH/DDX25. Enzyme Commission Number: EC 3.6.4.13. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4703; RNA helicase; EC 3.6.4.13; CSFV NS3 helicase; DBP2; DbpA; DDX17; DDX25; DDX3; DDX3X; DDX3Y; DDX4; DDX5; DEAD-box protein DED1; DEAD-box RNA helicase; DEAH-box protein 2; DEAH-box RNA helicase; DED1; Dex(H/D) RNA helicase; EhDEAD1; EhDEAD1 RNA helicase; eIF4A helicase; KOKV helicase; Mtr4p; nonstructural protein 3 helicase; NPH-II; RHA; RNA helicase A; RNA helicase DDX3; RNA helicase Hera; RNA-dependent ATPase; TGBp1 NTPase/helicase domain; VRH1; GRTH/DDX25. Cat No: EXWM-4703. |  |
| ATP-dependent RNA helicase DDX5 (148-156) | ATP-dependent RNA helicase DDX5 (148-156) is a fragment of ATP-dependent RNA helicase DDX5. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. It can be used in Ovarian carcinoma research. Synonyms: DEAD box protein 5 (148-156); RNA helicase p68 (148-156). |  |
| Avenanthramide A | Avenanthramide A is a phytoalexin, which can be found in oats ( Avena sativa L. ). Avenanthramide A targets the RNA helicase DDX3 , leads to mitochondrial swelling and increased ROS production, and induces apoptosis in CRC cells. Avenanthramide A exhibits antitumor efficacy in mouse model. Avenanthramide A orally active [1]. Uses: Scientific research. Group: Natural products. CAS No. 108605-70-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-114977. |  |
| DNA helicase | DNA helicases utilize the energy from ATP hydrolysis to unwind double-stranded DNA. Some of them unwind duplex DNA with a 3' to 5' polarity, others show 5' to 3' polarity or unwind DNA in both directions. Some helicases unwind DNA as well as RNA. May be identical with EC 3.6.4.13 (RNA helicase). Group: Enzymes. Synonyms: 3' to 5' DNA helicase; 3'-5' DNA helicase; 3'-5' PfDH; 5' to 3' DNA helicase; AvDH1; BACH1 helicase; BcMCM; BLM protein; BRCA1-associated C-terminal helicase; CeWRN-1; Dbp9p; DmRECQ5; DNA helicase 120; DNA helicase A; DNA helicase E; DNA helicase I. Enzyme Commission Number: EC 3.6.4.12. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4702; DNA helicase; EC 3.6.4.12; 3' to 5' DNA helicase; 3'-5' DNA helicase; 3'-5' PfDH; 5' to 3' DNA helicase; AvDH1; BACH1 helicase; BcMCM; BLM protein; BRCA1-associated C-terminal helicase; CeWRN-1; Dbp9p; DmRECQ5; DNA helicase 120; DNA helicase A; DNA helicase E; DNA helicase II; DNA helicase III; DNA helicase RECQL5β; DNA helicase VI; dnaB; DnaB helicase E1; helicase HDH IV; Hel E; helicase DnaB; helicase domain of bacteriophage T7 gene 4 protein helicase; PcrA helicase; UvrD; hHcsA; Hmi1p; hPif1; MCM helicase; MCM protein; MER3 helicase; MER3 protein; MPH1; PcrA; PcrA helicase; PDH120; PfDH A; Pfh1p; PIF1. Cat No: EXWM-4702. | |
| γ-[(8-Aminooctyl)-imido]-XTP | γ-[(8-Aminooctyl)-imido]-XTP, a biochemical reagent utilized for studying enzymes involved in RNA synthesis and processing, mimics ATP's structure and has demonstrated compatibility as a substrate for RNA polymerases. This versatile compound enables research on ribonucleases and ATP-dependent RNA helicases. Moreover, its utility extends to the study of the HIV-1 reverse transcriptase enzyme. Synonyms: γ-[(8-Aminooctyl)-imido]-xanthosine-5'-triphosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C18H33N6O14P3(free acid). Mole weight: 650.41 (free acid). | |
| Heliquinomycin (Rubymycin, NSC 702208) | Antibiotic. DNA helicase inhibitor. Inhibits the DNA helicase activity of the human minichromosome maintenance (MCM) 4/6/7 complex. Topoisomerase I and II inhibitor (weaker than DNA helicase). DNA and RNA synthesis inhibitor in cell culture. Does not inhibit protein synthesis. Induces cell cycle arrest. Anticancer compound. Antibacterial against Gram-positive bacteria. Group: Biochemicals. Grades: Purified. CAS No. 178182-49-5. Pack Sizes: 250ug, 500ug. Molecular Formula: C33H30O17. US Biological Life Sciences. |  Worldwide |
| ribonuclease E | RNase E is a bacterial ribonuclease that plays a role in the processing of ribosomal RNA (9S to 5S rRNA), the chemical degradation of bulk cellular RNA, the decay of specific regulatory, messenger and structural RNAs and the control of plasmid DNA replication. The enzyme binds to monophosphorylated 5' ends of substrates but exhibits sequential cleavages in the 3' to 5' direction. 2'-O-Methyl nucleotide substitutions at RNase E binding sites do not prevent binding but do prevent cleavage of non-modified target sequences 5' to that locus. In Escherichia coli, the enzyme is found in the RNA degradosome. The C-terminal half of the protein contains binding sites for the three other major degradosomal components, the DEAD-box RNA helicase Rh1B, enolase (EC 4.1.1.11) and polynucleotide phosphorylase (EC 2.7.7.8). Group: Enzymes. Synonyms: endoribonuclease E; RNase E; Rne protein. Enzyme Commission Number: EC 3.1.26.12. CAS No. 76106-82-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3588; ribonuclease E; EC 3.1.26.12; 76106-82-6; endoribonuclease E; RNase E; Rne protein. Cat No: EXWM-3588. | |
| RK-33 | RK-33 is an RNA helicase inhibitor against DDX3, and inhibits its helicase activity. Uses: Scientific research. Group: Signaling pathways. CAS No. 1070773-09-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100455. | |
| YK-4-279 | YK-4-279 blocks RNA Helicase A (RHA) binding with EWS-FLI1 (oncogenic protein). YK-4-279 induces apoptosis and shows anti-proliferation activities towards various cancer cells. YK-4-279 has a chiral center and it can be separated into two enantiomers. YK-4-279 can be used for the research of cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1037184-44-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14507. | |
| YK-4-279 | YK-4-279 is a potent inhibitor of EWS-FLI1 binding to RNA helicase A (RHA).YK-4-279 eliminates cyclin D levels by blocking the interaction of EWS-FLI1 with RHA in EWS-FLI1-containing TC32 cells. Synonyms: YK-4-279; YK4-279; YK 4-279; YK-4279; YK4279; YK 4279. Grades: >98%. CAS No. 1037184-44-3. Molecular formula: C17H13Cl2NO4. Mole weight: 366.20. | |
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