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| Product | Description | |
|---|---|---|
| s-Adenosyl-1,12-diamino-3-thio-9-azadodecane | Heterocyclic Organic Compound. CAS No. 118436-57-0. Catalog: ACM118436570. |  |
| S-Adenosyl-DL-methionine | S-Adenosyl-DL-methionine is a derivative of Ademetionine (HY-B0617). Ademetionine is an intermediate metabolite of methionine [1]. Uses: Scientific research. Group: Natural products. CAS No. 17176-17-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-126126. |  |
| S-Adenosyl-Homocysteine | S-Adenosyl-homocysteine hydrolyzes in acid solution (0.1M HCl, 100°C, over 90 minutes) to form S-ribosylhomocysteine. It is not hydrolyzed in neutral alkaline solutions (stable in 0.1M NaOH at 25°C over 10 minutes), but oxidation is more rapid in alkaline solution. S-Adenosyl-homocysteine is slowly oxidized to the sulfoxide as a solid and in solution. It is protected from oxidation by thiodiglycol; neutral solutions containing thiodiglycol are stable for long periods at 25°C. Group: Biochemicals. Grades: Highly Purified. CAS No. 979-92-0. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| S-adenosylhomocysteine deaminase | This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. Group: Enzymes. Synonyms: adenosylhomocysteine deaminase. Enzyme Commission Number: EC 3.5.4.28. CAS No. 125149-24-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4555; S-adenosylhomocysteine deaminase; EC 3.5.4.28; 125149-24-8; adenosylhomocysteine deaminase. Cat No: EXWM-4555. |  |
| S-ADENOSYL-L-CYSTEINE | Cas No. 35899-53-7. Molecular formula: C13H18N6O5S. Mole weight: 370.38. |  |
| s-Adenosyl-L-ethionine iodide | Heterocyclic Organic Compound. CAS No. 102029-72-1. Catalog: ACM102029721. | |
| S-adenosyl-L-homocysteine | S-adenosyl-L-homocysteine. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-2-amino-4-((((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)thio)butanoic acid. CAS No. 979-92-0. Molecular Formula: C14H20N6O5S. Mole Weight: 384.41. Catalog: APB979920. |  |
| S-Adenosyl-L-Homocysteine Hydrolase, Recombinant | Enzyme in vertebrates which catabolizes S-adenosyl-L-homocysteine. S-adenosyl-l-homocysteine hydrolase (sahh, ec 3.3.1.1) (adohcyase) is an enzyme of the activated methyl cycle, responsible for the reversible hydration of s-adenosyl-l-homocysteine into adenosine and homocysteine. sahh is a ubiquitous enzyme which binds and requires nad+ as a cofactor. adohcyase is a highly conserved protein of about 430 to 470 amino acids. the family contains a glycine-rich region in the central part of adohcyase; aregion thought to be involved in nad-binding. this protein may use themorpheein model of allosteric regulation. Group: Enzymes. Synonyms: Adenosylhomocysteinase; EC 3.3.1.1; S-adenosylhomocysteine synthase; S-adenosylhomocysteine hydrolase; adenosylhomocysteine hydrolase (ambiguous); S-adenosylhomocyste. Enzyme Commission Number: EC 3.3.1.1. Purity: >90% (SDS-PAGE test). Mole weight: About 44kDa (SDS-PAGE detection). Activity: 140U/mg. Appearance: White powder, lyophilized. Storage: Redissolved in 20% glycerol, 4°C, store at -20°C for long-term preservation, Avoid multiple freeze-thaw cycles. Form: Freeze dried powder. Adenosylhomocysteinase; EC 3.3.1.1; S-adenosylhomocysteine synthase; S-adenosylhomocysteine hydrolase; adenosylhomocysteine hydrolase (ambiguous); S-adenosylhomocysteinase; SAHase; AdoHcyase; 9025-54-1. Cat No: NATE-1150. | |
| S-Adenosyl-L-methionine | S-Adenosyl-L-methionine. Group: Biochemicals. Alternative Names: SAMe. Grades: Highly Purified. CAS No. 29908-03-0. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C15H22N6O5S, Molecular Weight: 398.44. US Biological Life Sciences. | Worldwide |
| S-Adenosyl-L-Methionine | S-adenosyl-l-methionine (SAMe) is a naturally occurring substance which is a major source of methyl groups in the brain. The efficacy of SAMe in treating depressive syndromes and disorders is superior to that of placebo and comparable to that of standard tricyclic antidepressants. Since SAMe is a naturally occurring compound with relatively few side effects, it is a potentially important treatment for depression. S-adenosylmethionine (SAMe) is a dietary supplement used in the management of osteoarthritis (OA) symptoms. Studies evaluating SAMe in the management of OA have been limited to Non Steroidal Anti-inflammatory Drugs (NSAIDs) for comparison. The present study compares the effectiveness of SAMe to a cyclooxygenase-2 (COX-2) inhibitor (celecoxib) for pain control, functional improvement and to decrease side effects in people with osteoarthritis of the knee. It also acts as a PDE4B inhibitor. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Ademetionine; AdoMet; MSI-195; MSI 195; MSI195; SAMe; S-adenosylmethionine. Heptral; Gumbaral. S-Adenosyl-L-methionine; S-Adenosyl methionine; SAMe; AdoMet; (2S)-2-amino-4-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl-methylsulfonio]butanoate. Grades: 98%. CAS No. 29908-03-0. Molecular formula: C15H22N6O5S. Mole weight: 398.438. | |
| S-Adenosyl-L-methionine chloride dihydrochloride | S-Adenosyl-L-methionine (S-Adenosyl methionine) chloride dihydrochloride is a methyl donor and cofactor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S-Adenosyl methionine chloride dihydrochloride; Ademetionine chloride dihydrochloride; AdoMet chloride dihydrochloride. CAS No. 86867-01-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-14614A. | |
| S-Adenosyl-L-methionine Disulfate Tosylate (doMet SAM Disulfate p-toluenesulfonate, SAMe) | A methyl donor and a cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. SAM is anti-apoptotic in normal hepatocytes and normal colon epithelial cells but pro-apoptotic in liver human hepatocellular carcinoma (HCC), HepG2 cells and colon cancer cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 97540-22-2. Pack Sizes: 50g, 100g, 250g, 500g. Molecular Formula: C??H??N?O??S?, Molecular Weight: 766.8. US Biological Life Sciences. | Worldwide |
| S-Adenosyl-L-methionine p-toluenesulfonate | S-(5?-Adenosyl)-L-methionine (SAM) is anti-apoptotic in normal hepatocytes and normal colon epithelial cells but pro-apoptotic in liver human hepatocellular carcinoma (HCC), HepG2 cells and colon cancer cells. Methyl donor; cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. It is also involved in regulating liver function, growth, and response to injury. Group: Biochemicals. Alternative Names: (3S) -5'-[ (3-Amino-3-carboxylatopropyl) methylsulphonio]-5'-deoxyadenosine) ; SAMe p-toluenesulfonate; S-Adenosylmethionine Tosylate; Adomet; Ademetionine. Grades: Highly Purified. CAS No. 17176-17-9. Pack Sizes: 10g, 25g, 50g, 100g. US Biological Life Sciences. | Worldwide |
| S-Adenosyl-L-methionine p-toluenesulfonate | S-Adenosyl-L-methionine p-toluenesulfonate, a vital compound harnessed within the biomedical sector, assumes a pivotal position as a cofactor amidst the intricate processes involved in neurotransmitter, DNA, and protein synthesis. Predominantly employed to address myriad liver afflictions such as chronic liver disease and cholestasis, this product's therapeutic efficacy extends to mood disorders by fostering regulation of neurotransmitter equilibrium, specifically targeting depression. Synonyms: S-(5'-Adenosyl)-L-methionine tosylate; Adenosine, 5'-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5'-deoxy-, 4-methylbenzenesulfonate (1:1); Adenosine, 5'-[(3-amino-3-carboxypropyl)methylsulfonio]-5'-deoxy-, (3S)-, 4-methylbenzenesulfonate (salt); Adenosine, 5'-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5'-deoxy-, salt with 4-methylbenzenesulfonic acid (1:1); S-Adenosylmethionine toluene-p-sulfonate; S-Adenosylmethionine tosylate; SAMe p-toluenesulfonate. Grades: 95%. CAS No. 52248-03-0. Molecular formula: C15H23N6O5S.C7H7O3S. Mole weight: 570.64. | |
| S-Adenosyl-L-methionine tosylate | S-Adenosyl-L-methionine tosylate is produced endogenously from methionine and ATP by action of the enzyme methionine adenosyltransferase and is an important orally active methyl group donor. S-Adenosyl-L-methionine tosylate is a dietary supplement with potent antidepressant and analgesic effects, and has the potential for liver disease and osteoarthritis research [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: S-Adenosyl methionine tosylate; Ademetionine tosylate; AdoMet tosylate. CAS No. 52248-03-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-B0617A. | |
| S-Adenosylmethione-1,4-butanedisulfonate | Ademethionine 1,4-Butanedisulfonate is used in the synthesis of sulfonio-adenosyl-L-methionine (SAMe) salts. Group: Biochemicals. Grades: Highly Purified. CAS No. 101020-79-5. Pack Sizes: 2g, 5g, 10g, 25g, 50g. Molecular Formula: C19H33N6O11S3. 1/2(C4H8O6S2), Molecular Weight: 1451.63. US Biological Life Sciences. | Worldwide |
| S-adenosylmethionine synthetase, Recombinant | S-adenosylmethionine synthetase (EC 2.5.1.6) (also known as methionine adenosyltransferase (MAT)) is an enzyme that creates S-adenosylmethionine (AdoMet) by reacting methionine (a non-polar amino acid) and ATP (the basic currency of energy). AdoMet is a methyl donor for transmethylation. It gives away its methyl group and is also the propylamino donor in polyamine biosynthesis. S-adenosylmethionine synthetasecan be considered the rate-limiting step of the methionine cycle. S-adenosylmethionine (sam) is a methyl donor and allows dna methylation. once dna is methylated, it switches the genes off and therefore, s-adenosylmethionine can be considered tocontrol gene expressi...denosylmethioninesynthase isoform type-1; AdoMet synthase 1; MAT 1; Methionineadenosyltransferase I/III; MAT-I/III; MAT1A; AMS1. Enzyme Commission Number: EC 2.5.1.6. Purity: >90% (SDS-PAGE test). Mole weight: About 46kDa (SDS-PAGE detection). Activity: >700U/mg. Appearance: White powder, lyophilized. Storage: Redissolved in 30% glycerol, 4°C, store at -20°C/-80°C for long-term preservation, Avoid multiple freeze-thaw cycles. Form: Freeze dried powder. EC 2.5.1.6; MAT; MATA1; SAMS; SAMS1; Methionine adenosyltransferase 1; S-adenosylmethioninesynthase isoform type-1; AdoMet synthase 1; MAT 1; Methionineadenosyltransferase I/III; MAT-I/III; MAT1A; AMS1. Cat No: NATE-1151. | |
| S-adenosylmethionine:tRNA ribosyltransferase-isomerase | The reaction is a combined transfer and isomerization of the ribose moiety of S-adenosyl-L-methionine to the modified guanosine base in the wobble position in tRNAs specific for Tyr, His, Asp or Asn. It is part of the queuosine biosynthesis pathway. Group: Enzymes. Synonyms: QueA enzyme; queuosine biosynthesis protein QueA. Enzyme Commission Number: EC 2.4.99.17. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2701; S-adenosylmethionine:tRNA ribosyltransferase-isomerase; EC 2.4.99.17; QueA enzyme; queuosine biosynthesis protein QueA. Cat No: EXWM-2701. | |
| Decarboxylated S-Adenosylmethionine Iodide | Decarboxylated S-adenosyl methionine is a substrate that is involved in the biosynthesis of polyamines including spermidine, spermine, and thermospermine. Synonyms: 5'-[(3-aminopropyl)methylsulfonio]-5'-deoxy-adenosine Iodide; (-)-S-Adenosyl-(5')-3-methylthiopropylamine Iodide; Decarboxylated AdoMet Iodide; S-Adenosyl-3-methylthiopropylamine Iodide; S-Adenosyl-L-methionamine Iodide; S-Adenosylmethionamine Iodide; S-M. Grades: > 95%. Molecular formula: C14H23N6O3SI. Mole weight: 482.34. | |
| 1,3-dimethyl-1H-indazol-6-amine | 1,3-dimethyl-1H-indazol-6-amine is an impurity in the synthesis of Pazopanib (P210925) which is an oral angiogenesis inhibitor targeting VEGFR and PDGFR. It is used as a reagent in the preparation of glycinamide derivatives which are useful in production of drugs for preventing and treating diseases caused by S-adenosyl homocysteine hydrolase. Group: Biochemicals. Grades: Highly Purified. CAS No. 221681-92-1. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C9H11N3, Molecular Weight: 161.199999999999. US Biological Life Sciences. | Worldwide |
| 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase | KsgA introduces the most highly conserved ribosomal RNA modification, the dimethylation of adenine1518 and adenine1519 in 16S rRNA. Strains lacking the methylase are resistant to kasugamycin. Group: Enzymes. Synonyms: S-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase; KsgA; ksgA methyltransferase. Enzyme Commission Number: EC 2.1.1.182. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1781; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase; EC 2.1.1.182; S-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase; KsgA; ksgA methyltransferase. Cat No: EXWM-1781. | |
| 1-aminocyclopropane-1-carboxylate synthase | A pyridoxal-phosphate protein. The enzyme catalyses an α,γ-elimination. Group: Enzymes. Synonyms: 1-aminocyclopropanecarboxylate synthase; 1-aminocyclopropane-1-carboxylic acid synthase; 1-aminocyclopropane-1-carboxylate synthetase; aminocyclopropanecarboxylic acid synthase; aminocyclopropanecarboxylate synthase; ACC synthase; S-adenosyl-L-methionine methylthioadenosine-lyase. Enzyme Commission Number: EC 4.4.1.14. CAS No. 72506-68-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5316; 1-aminocyclopropane-1-carboxylate synthase; EC 4.4.1.14; 72506-68-4; 1-aminocyclopropanecarboxylate synthase; 1-aminocyclopropane-1-carboxylic acid synthase; 1-aminocyclopropane-1-carboxylate synthetase; aminocyclopropanecarboxylic acid synthase; aminocyclopropanecarboxylate synthase; ACC synthase; S-adenosyl-L-methionine methylthioadenosine-lyase. Cat No: EXWM-5316. | |
| 2',?3'-?O-?(1-?Methylethylidene)?-?5'-?thio-?adenosine 5'-?Acetate | 2',?3'-O-(1-Methylethylidene)?-5'-thio-adenosine 5'-Acetate is an intermediate in synthesizing Decarboxylated S-Adenosylmethionine Sulfate Salt, a substrate that is involved in the biosynthesis of polyamines including spermidine, spermine, and thermospermine. Synonyms: Furo[3,4-d]-1,3-dioxole Adenosine Derivative; S-(((3aS,4S,6R,6aR)-6-(6-Amino-9H-purin-9-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl) Ethanethioate. CAS No. 84365-04-8. Molecular formula: C15H19N5O4S. Mole weight: 365.41. | |
| 2',?3'-?O-?(1-?Methylethylidene)?-?5'-?thio-?adenosine 5'-?Acetate | 2',?3'-?O-?(1-?Methylethylidene)?-?5'-?thio-?adenosine 5'-?Acetate is an intermediate in synthesizing Decarboxylated S-Adenosylmethionine Sulfate Salt (D222000), a substrate that is involved in the biosynthesis of polyamines including spermidine, spermine, and thermospermine. Group: Biochemicals. Grades: Highly Purified. CAS No. 84365-04-8. Pack Sizes: 50mg, 100mg. Molecular Formula: C15H19N5O4S. US Biological Life Sciences. | Worldwide |
| 23S rRNA (adenine2503-C2)-methyltransferase | Contains an [4Fe-4S] cluster. This enzyme is a member of the 'AdoMet radical' (radical SAM) family. S-Adenosyl-L-methionine acts as both a radical generator and as the source of the appended methyl group. RlmN first transfers an CH2 group to a conserved cysteine (Cys355 in Escherichia coli), the generated radical from a second S-adenosyl-L-methionine then attacks the methyl group, exctracting a hydrogen. The formed radical forms a covalent intermediate with the adenine group of the tRNA. RlmN is an endogenous enzyme used by the cell to refine functions of the ribosome in protein synthesis. The enzyme methylates adenosine by a radical mechanism with CH2 from the S-adenosyl-L-methionine and retention of the hydrogen at C-2 of adenosine2503 of 23S rRNA. It will also methylate 8-methyladenosine2503 of 23S rRNA. cf. EC 2.1.1.224 [23S rRNA (adenine2503-C8)-methyltransferase]. Group: Enzymes. Synonyms: RlmN; YfgB; Cfr. Enzyme Commission Number: EC 2.1.1.192. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1792; 23S rRNA (adenine2503-C2)-methyltransferase; EC 2.1.1.192; RlmN; YfgB; Cfr. Cat No: EXWM-1792. | |
| 23S rRNA (adenine2503-C8)-methyltransferase | This enzyme is a member of the 'AdoMet radical' (radical SAM) family. S-Adenosyl-L-methionine acts as both a radical generator and as the source of the appended methyl group. It contains an [4Fe-S] cluster. Cfr is an plasmid-acquired methyltransferase that protects cells from the action of antibiotics. The enzyme methylates adenosine at position 2503 of 23S rRNA by a radical mechanism, transferring a CH2 group from S-adenosyl-L-methionine while retaining the hydrogen at the C-8 position of the adenine. Cfr first transfers an CH2 group to a conserved cysteine (Cys338 in Staphylococcus aureus), the generated radical from a second S-adenosyl-L-methionine then attacks the methyl group, exctracting a hydrogen. The formed radical forms a covalent intermediate with the adenine group of the tRNA. The enzyme will also methylate 2-methyladenine produced by the action of EC 2.1.1.192 [23S rRNA (adenine2503-C2)-methyltransferase]. Group: Enzymes. Synonyms: Cfr (gene name). Enzyme Commission Number: EC 2.1.1.224. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1827; 23S rRNA (adenine2503-C8)-methyltransferase; EC 2.1.1.224; Cfr (gene name). Cat No: EXWM-1827. | |
| 23S rRNA (cytidine2498-2'-O)-methyltransferase | 23S rRNA (cytidine2498-2'-O)-methyltransferase (EC 2.1.1.186, YgdE, rRNA large subunit methyltransferase M, RlmM) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (cytidine2498-2'-O-)-methyltransferase. Group: Enzymes. Synonyms: YgdE; rRNA large subunit methyltransferase M; RlmM. Enzyme Commission Number: EC 2.1.1.186. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1785; 23S rRNA (cytidine2498-2'-O)-methyltransferase; EC 2.1.1.186; YgdE; rRNA large subunit methyltransferase M; RlmM. Cat No: EXWM-1785. | |
| 2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase | Specifically methylates 2,4',7-trihydroxyisoflavanone on the 4'-position. No activity with isoflavones. The enzyme is involved in formononetin biosynthesis in legumes. The protein from pea (Pisum sativum) also methylates (+)-6a-hydroxymaackiain at the 3-position (cf. EC 2.1.1.270, (+)-6a-hydroxymaackiain 3-O-methyltransferase). Group: Enzymes. Synonyms: SAM:2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase; HI4'OMT; HMM1; MtIOMT5; S-adenosyl-L-methionine:2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase. Enzyme Commission Number: EC 2.1.1.212. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1814; 2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase; EC 2.1.1.212; SAM:2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase; HI4'OMT; HMM1; MtIOMT5; S-adenosyl-L-methionine:2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase. Cat No: EXWM-1814. | |
| 2-Amino-4-phenoxybutanoic Acid | 2-Amino-4-phenoxybutanoic Acid has inhibitory effects on ATP:L-methionine S-adenosyltransferase in rat liver. Group: Biochemicals. Grades: Highly Purified. CAS No. 52161-80-5. Pack Sizes: 50mg, 100mg. Molecular Formula: C10H13NO3, Molecular Weight: 195.22. US Biological Life Sciences. | Worldwide |
| 2-Cyanomethylthioadenosine | 2-Cyanomethylthioadenosine, a powerful inhibitor of S-adenosylhomocysteine hydrolase (SAHH), the regulator of methylation pressure and a participant in the development of cancer, is a highly effective modulator of extracellular metabolism, opening doors for therapeutic interventions in cancer, inflammation, and immunomodulation, illuminating its status as a multifaceted agent at the cutting-edge of biochemistry. Grades: ≥95%. CAS No. 2095417-67-5. Molecular formula: C12H14N6O4S. Mole weight: 338.34. | |
| 2'-Deoxyadenosine | 2'-Deoxyadenosine is a purine nucleoside composed of Adenine (HY-B0152) and 2'-deoxyribose. 2'-Deoxyadenosine activates Caspase-3 and promotes Apoptosis. 2'-Deoxyadenosine inhibits the activity of S-adenosyl-L-homocysteine hydrolase. 2'-Deoxyadenosine inhibits the growth of various cells. 2'-Deoxyadenosine has an anticancer effect on colon cancer [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Natural products. CAS No. 958-09-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-W040329. | |
| 2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent) | Involved in the biosynthetic pathway of the aminoglycoside antibiotics of the butirosin family. The enzyme from Bacillus circulans was shown to be a radical S-adenosyl-L-methionine (SAM) enzyme. cf. EC 1.1.1.329, 2-deoxy-scyllo-inosamine dehydrogenase. Group: Enzymes. Synonyms: btrN (gene name); 2-deoxy-scyllo-inosamine dehydrogenase (SAM-dependent). Enzyme Commission Number: EC 1.1.99.38. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0466; 2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent); EC 1.1.99.38; btrN (gene name); 2-deoxy-scyllo-inosamine dehydrogenase (SAM-dependent). Cat No: EXWM-0466. | |
| 2-iminoacetate synthase | Binds a [4Fe-4S] cluster that is coordinated by 3 cysteines and an exchangeable S-adenosyl-L-methionine molecule. The first stage of catalysis is reduction of the S-adenosyl-L-methionine to produce methionine and a 5-deoxyadenosin-5-yl radical that is crucial for the conversion of the substrate. The reductant is assumed to be NADPH, which is provided by a flavoprotein:NADPH oxidoreductase system. Part of the pathway for thiamine biosynthesis. Group: Enzymes. Synonyms: thiH (gene name). Enzyme Commission Number: EC 4.1.99.19. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4932; 2-iminoacetate synthase; EC 4.1.99.19; thiH (gene name). Cat No: EXWM-4932. | |
| 2-Methyl-4-pyrimidinyl-boronic Acid | 2-Methyl-4-pyrimidinyl-boronic Acid is used to synthesize indazole-derived S-adenosyl homocysteine / methylthioadenosine nucleosidase inhibitors with antimicrobial activities. Group: Biochemicals. Grades: Highly Purified. CAS No. 647853-31-4. Pack Sizes: 100mg, 1g. Molecular Formula: C5H7BN2O2, Molecular Weight: 137.93. US Biological Life Sciences. | Worldwide |
| 3,7-dimethylquercetin 4'-O-methyltransferase | 3,7-Dimethylquercetagetin can also act as acceptor. Involved with EC 2.1.1.76 quercetin 3-O-methyltransferase and EC 2.1.1.82 3-methylquercetin 7-O-methyltransferase in the methylation of quercetin to 3,7,4'-trimethylquercetin in Chrysosplenium americanum. Does not act on flavones, dihydroflavonols, or their glucosides. Group: Enzymes. Synonyms: flavonol 4'-O-methyltransferase; flavonol 4'-methyltransferase; 4'-OMT; S-adenosyl-L-methionine:3',4',5-trihydroxy-3,7-dimethoxyflavone 4'-O-methyltransferase; 3,7-dimethylquercitin 4'-O-methyltransferase [mis-spelt]. Enzyme Commission Number: EC 2.1.1.83. CAS No. 96477-60-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1984; 3,7-dimethylquercetin 4'-O-methyltransferase; EC 2.1.1.83; 96477-60-0; flavonol 4'-O-methyltransferase; flavonol 4'-methyltransferase; 4'-OMT; S-adenosyl-L-methionine:3',4',5-trihydroxy-3,7-dimethoxyflavone 4'-O-methyltransferase; 3,7-dimethylquercitin 4'-O-methyltransferase [mis-spelt]. Cat No: EXWM-1984. | |
| 3-Deazaadenosine | 3-Deazaadenosine is an inhibitor of S-adenosylhomocysteine hydrolase, with a Ki of 3.9 μM; 3-Deazaadenosine has anti-inflammatory, anti-proliferative and anti-HIV activity. Group: Inhibitors. CAS No. 6736-58-9. Molecular formula: C11H14N4O4. Mole weight: 266.25. Appearance: Solid. Canonical SMILES: O[C@H]1[C@@H] (O[C@H] (CO)[C@H]1O)N2C3=C (C (N)=NC=C3)N=C2. Catalog: ACM6736589. | |
| 3-Deazaadenosine | 3-Deazaadenosine is an inhibitor of S-adenosylhomocysteine hydrolase , with a K i of 3.9 μM; 3-Deazaadenosine has anti-inflammatory, anti-proliferative and anti- HIV activity. Uses: Scientific research. Group: Signaling pathways. CAS No. 6736-58-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-W013332. | |
| 3-Deazaadenosine hydrochloride | 3-Deazaadenosine (hydrochloride) is an inhibitor of S-adenosylhomocysteine hydrolase , with a K i of 3.9 μM; 3-Deazaadenosine has anti-inflammatory, anti-proliferative and anti- HIV activity. Uses: Scientific research. Group: Signaling pathways. CAS No. 86583-19-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-W013332A. | |
| 3-Deazaneplanocin A | 3-Deazaneplanocin A (DZNep) is a potent histone methyltransferase EZH2 inhibitor [1] [2]. 3-Deazaneplanocin A is a potent S-adenosylhomocysteine hydrolase (AHCY) inhibitor. 3-Deazaneplanocin A shows anti-orthopoxvirus activity [6] [7]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DZNep; 3-Deazaneplanocin. CAS No. 102052-95-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-10442. | |
| 3-Deazaneplanocin A | 3-Deazaneplanocin A is a a powerful inhibitor of S-adenosylhomocysteine hydrolase that has shown potent and selective in vitro and in vivo antiviral activities. Group: Biochemicals. Alternative Names: (1S,2R,5R)-5-(4-Amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1,2-diol Hydrochloride;[1S-(1α,2α,5 β)]-5-(4-Amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1,2-diol Monohydrochloride. Grades: Highly Purified. CAS No. 120964-45-6. Pack Sizes: 500ug, 1mg, 5mg. Molecular Formula: C??H??ClN?O?, Melting Point: >185°C (dec.). US Biological Life Sciences. | Worldwide |
| 3-Deazaneplanocin A | 3-Deazaneplanocin A is an inhibitor of S-adenosylmethionine-dependent methyltransferase. In combination with sodium butyrate, 3-Deazaneplanocin A can induce epigenetically reprogramming of human embryonic stem cells (hESC). Synonyms: DZNep; (1S,2R,5R)-5-(4-aminoimidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol. Grades: >98%. CAS No. 102052-95-9. Molecular formula: C12H14N4O3. Mole weight: 262.26. | |
| 3-deazaneplanocin A (DZNeP) HCl | 3-deazaneplanocin A (DZNeP)HCl, an analog of adenosine, is a competitive inhibitor of S-adenosylhomocysteine hydrolase with Ki of 50 pM. Synonyms: NSC 617989 HCl; NSC617989 HCl; NSC-617989 HCl; 3-deazaneplanocin A HCl; 3-deazaneplanocin A hydrochloride; DZNep. Grades: >98%. CAS No. 120964-45-6. Molecular formula: C12H15ClN4O3. Mole weight: 298.72. | |
| 3-Deazaneplanocin A hydrochloride | 3-Deazaneplanocin A hydrochloride (DZNep hydrochloride) is a potent histone methyltransferase EZH2 inhibitor [1] [2]. 3-Deazaneplanocin A hydrochlorideis a potent S-adenosylhomocysteine hydrolase (AHCY) inhibitor [6]. 3-Deazaneplanocin A hydrochloride also has anti- orthopoxvirus and anti-variola activities [7]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DZNep hydrochloride; NSC 617989 hydrochloride; 3-Deazaneplanocin hydrochloride. CAS No. 120964-45-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12186. | |
| 3-demethylubiquinol 3-O-methyltransferase | This enzyme is involved in ubiquinone biosynthesis. Ubiquinones from different organisms have a different number of prenyl units (for example, ubiquinone-6 in Saccharomyces, ubiquinone-9 in rat and ubiquinone-10 in human), and thus the natural substrate for the enzymes from different organisms has a different number of prenyl units. However, the enzyme usually shows a low degree of specificity regarding the number of prenyl units. For example, the human COQ3 enzyme can restore biosynthesis of ubiquinone-6 in coq3 deletion mutants of yeast.The enzymes from yeast, Escherichia coli and rat also catalyse the methylation of 3,4-dihydroxy-5-all-trans-polyprenylbenzoate (a reac...COQ3 (gene name); Coq3 O-methyltransferase; ubiG (gene name, ambiguous). Enzyme Commission Number: EC 2.1.1.64. CAS No. 63774-48-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1966; 3-demethylubiquinol 3-O-methyltransferase; EC 2.1.1.64; 63774-48-1; 5-demethylubiquinone-9 methyltransferase; OMHMB-methyltransferase; 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone methyltransferase; S-adenosyl-L-methionine:2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone-O-methyltransferase; COQ3 (gene name); Coq3 O-methyltransferase; ubiG (gene name, ambiguous). Cat No: EXWM-1966. | |
| 3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase | Involved in the biosynthesis of vindoline from tabersonine in the Madagascar periwinkleCatharanthus roseus. Group: Enzymes. Synonyms: 16-methoxy-2,3-dihydro-3-hydroxytabersonine methyltransferase; NMT; 16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase; S-adenosyl-L-methionine:16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase. Enzyme Commission Number: EC 2.1.1.99. CAS No. 113478-40-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1999; 3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase; EC 2.1.1.99; 113478-40-3; 16-methoxy-2,3-dihydro-3-hydroxytabersonine methyltransferase; NMT; 16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase; S-adenosyl-L-methionine:16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase. Cat No: EXWM-1999. | |
| 3-methylquercetin 7-O-methyltransferase | Involved with EC 2.1.1.76 quercetin 3-O-methyltransferase and EC 2.1.1.83 3,7-dimethylquercetin 4'-O-methyltransferase in the methylation of quercetin to 3,7,4'-trimethylquercetin in Chrysosplenium americanum. Does not act on flavones, dihydroflavonols, or their glucosides. Group: Enzymes. Synonyms: flavonol 7-O-methyltransferase; flavonol 7-methyltransferase; 7-OMT; S-adenosyl-L-methionine:3',4',5,7-tetrahydroxy-3-methoxyflavone 7-O-methyltransferase; 3-methylquercitin 7-O-methyltransferase [mis-spelt]. Enzyme Commission Number: EC 2.1.1.82. CAS No. 97089-67-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1983; 3-methylquercetin 7-O-methyltransferase; EC 2.1.1.82; 97089-67-3; flavonol 7-O-methyltransferase; flavonol 7-methyltransferase; 7-OMT; S-adenosyl-L-methionine:3',4',5,7-tetrahydroxy-3-methoxyflavone 7-O-methyltransferase; 3-methylquercitin 7-O-methyltransferase [mis-spelt]. Cat No: EXWM-1983. | |
| 5'-Chloro-5'-deoxyadenosine | 5'-Chloro-5'-deoxyadenosine (CAS# 892-48-8) is an intermediate in the synthesis of 5'-Deoxy-5'-(methylthio)adenosine (D242600), a substrate to study the specificity and kinetics of 5'-methylthioadenosinephosphorylase (MTAP) (EC2.4.2.28), a tumor suppressor gene expressed enzyme that supports the S-adenosylmethionine (AdoMet) and methionine salvage pathways. Synonyms: 5'-Chloroadenosine; 5'-deoxy-5'-chloroadenosine. Grades: 96 %. CAS No. 892-48-8. Molecular formula: C10H12ClN5O3. Mole weight: 285.69. | |
| 5'-Deoxy-5'-(dimethylsulfonio)adenosine Bromide | 5'-Deoxy-5'-(dimethylsulfonio)denosine Bromide is a derivative of Ademethionine, and potential design inhibitor of human S-adenosylmethionine decarboxylase. Synonyms: (((2S,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)dimethylsulfonium Bromide. CAS No. 1106914-63-9. Molecular formula: C12H18BrN5O3S. Mole weight: 392.27. | |
| 5'-Deoxy-5'-(methylthio)adenosine | 5'-Deoxy-5'-(methylthio)adenosine Bromide is a derivative of Ademethionine and is a potential design inhibitor of human S-adenosylmethionine decarboxylase. Synonyms: (2R, 3R, 4S, 5S) -2- (6-Amino-9H-purin-9-yl) -5- ( (methylsulfinyl) methyl) tetrahydrofuran-3, 4-diol. CAS No. 3387-65-3. Molecular formula: C11H15N5O4S. Mole weight: 313.33. | |
| 5'-Deoxy-5'-(methylthio)adenosine | 5?-Deoxy-5?-(methylthio)adenosine (Methylthioadenosine) may be used as a substrate to study the specificity and kinetics of 5?-methyl thioadenosine phosphoryl ase (MTAP) (EC2.4.2.28), a tumor suppressor gene expressed enzyme that supports the S-adenosylmethionine (AdoMet) and methionine salvage pathways. Methylthioadenosine is used in studies on bacterial quorum sensing pathways that envolve enzymes such as 5?-Methylthioadenosine/S-adenosylhomocysteine nucleosidase (MTAN). Group: Biochemicals. Alternative Names: 5'-S-Methyl-5'-thioadenosine; 5'-(Methylthio)-5'-deoxyadenosine; 5'-(Methylthio)adenosine; 5'-Deoxy (methylthio)adenosine; 5'-S-Methyl-5'-thioadenosine; 5'-S-Methylthioadenosine; NSC 335422; Vitamin L2; 1-(6-Amino-9H-purin-9-yl)-1-deoxy-5-S-methyl-5-thio- β-D-ribofuranose. Grades: Highly Purified. CAS No. 2457-80-9. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 5-hydroxyfuranocoumarin 5-O-methyltransferase | Converts bergaptol into bergapten, which has therapeutic potential in the treatment of psoriasis as it has photosensitizing and antiproliferative activities. The enzyme methylates the 5-hydroxy group of some hydroxy- and methylcoumarins, such as 5-hydroxyxanthotoxin, but has little activity on non-coumarin phenols. Caffeate, 5-hydroxyferulate and daphnetin are not substrates. Cu2+, Zn2+ and Co2+ cause enzyme inhibition. (see also EC 2.1.1.70, 8-hydroxyfuranocoumarin 8-O-methyltransferase). Group: Enzymes. Synonyms: furanocoumarin 5-methyltransferase; furanocoumarin 5-O-methyltransferase; bergaptol 5-O-methyltransferase; bergaptol O-methyltransferase; bergaptol methyltransferase; S-adenosyl-L-methionine:bergaptol O-methyltransferas. Enzyme Commission Number: EC 2.1.1.69. CAS No. 67339-12-2, 101637-31-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1970; 5-hydroxyfuranocoumarin 5-O-methyltransferase; EC 2.1.1.69; 67339-12-2, 101637-31-4; furanocoumarin 5-methyltransferase; furanocoumarin 5-O-methyltransferase; bergaptol 5-O-methyltransferase; bergaptol O-methyltransferase; bergaptol methyltransferase; S-adenosyl-L-methionine:bergaptol O-methyltransferase; BMT; S-adenosyl-L-methionine:5-hydroxyfuranocoumarin 5-O-methyltransferase. Cat No: EXWM-1970. | |
| 5'-Methylthioadenosine | 5'-Methylthioadenosine (5'-(Methylthio)-5'-deoxyadenosine) is a nucleoside generated from S-adenosylmethionine (SAM) during polyamine synthesis [1]. 5'-Methylthioadenosine suppresses tumors by inhibiting tumor cell proliferation, invasion, and the induction of apoptosis while controlling the inflammatory micro-environments of tumor tissue. 5'-Methylthioadenosine and its associated materials have striking regulatory effects on tumorigenesis [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 5'-(Methylthio)-5'-deoxyadenosine; 5'-Deoxy-5'-(methylthio)adenosine; 5'-S-Methyl-5'-thioadenosine. CAS No. 2457-80-9. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-16938. | |
| 5'-?S-?[3-? (1, ?3-?Dihydro-?1, ?3-?dioxo-?2H-?isoindol-?2-?yl) ?propyl]?-?2', ?3'-?O-? (1-?methylethylidene) ?-?5'-?thio-adenosine | 5'-S-[3-(1,?3-Dihydro-1,?3-dioxo-2H-isoindol-2-yl)?propyl]?-2',?3'-O-(1-methylethylidene)?-5'-thio-adenosine is an intermediate in synthesizing Decarboxylated S-Adenosylmethionine Sulfate Salt, a substrate that is involved in the biosynthesis of polyamines including spermidine, spermine, and thermospermine. Synonyms: 2-(3-((((3aS,4S,6R,6aR)-6-(6-Amino-9H-purin-9-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl)thio)propyl)isoindoline-1,3-dione. CAS No. 263715-50-0. Molecular formula: C24H26N6O5S. Mole weight: 510.57. | |
| 5'-?S-?(3-?Aminopropyl)?-?5'-?thio-adenosine Sulfate | 5'-S-(3-Aminopropyl)?-5'-thio-adenosine Sulfate is an intermediate in synthesizing Decarboxylated S-Adenosylmethionine Sulfate Salt, a substrate that is involved in the biosynthesis of polyamines including spermidine, spermine, and thermospermine. Synonyms: (2R, 3R, 4S, 5S) -2- (6-Amino-9H-purin-9-yl) -5- ( ( (3-aminopropyl) thio) methyl) tetrahydrofuran-3, 4-diol Sulfate. CAS No. 99019-00-8. Molecular formula: C13H20N6O3S H2SO4. Mole weight: 340.41. | |
| 6-Methylthio-guanosine | 6-Methylthio-guanosine, a petite molecule, offers a vantage point for investigating the intricate interplay between post-transcriptional modification and gene expression. Its structural resemblance to S-adenosylmethionine, along with a demonstrated impact on mRNA transcript stabilization and translation regulation, hold immense value for scientific investigations. Furthermore, its potential therapeutic applications in treating viral infections and cancer open up new avenues of exploration for the scientific community. Grades: ≥ 98%. Molecular formula: C11H15N5O4S. Mole weight: 313.33. | |
| 7-carboxy-7-deazaguanine synthase | Requires Mg2+. The enzyme is a member of the superfamily of S-adenosyl-L-methionine-dependent radical (radical AdoMet) enzymes. Binds a [4Fe-4S] cluster that is coordinated by 3 cysteines and an exchangeable S-adenosyl-L-methionine molecule. The S-adenosyl-L-methionine is catalytic as it is regenerated at the end of the reaction. The reaction is part of the biosynthesis pathway of queuosine. Group: Enzymes. Synonyms: 7-carboxy-7-carbaguanine synthase; queE (gene name). Enzyme Commission Number: EC 4.3.99.3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5310; 7-carboxy-7-deazaguanine synthase; EC 4.3.99.3; 7-carboxy-7-carbaguanine synthase; queE (gene name). Cat No: EXWM-5310. | |
| 7-methylxanthosine synthase | The enzyme is specific for xanthosine, as XMP and xanthine cannot act as substrates. The enzyme does not have N1- or N3- methylation activity. This is the first methylation step in the production of caffeine. Group: Enzymes. Synonyms: xanthosine methyltransferase; XMT; xanthosine:S-adenosyl-L-methionine methyltransferase; CtCS1; CmXRS1; CaXMT1; S-adenosyl-L-methionine:xanthosine 7-N-methyltransferase. Enzyme Commission Number: EC 2.1.1.158. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1754; 7-methylxanthosine synthase; EC 2.1.1.158; xanthosine methyltransferase; XMT; xanthosine:S-adenosyl-L-methionine methyltransferase; CtCS1; CmXRS1; CaXMT1; S-adenosyl-L-methionine:xanthosine 7-N-methyltransferase. Cat No: EXWM-1754. | |
| 8-Fluoroadenosine | 8-Fluoroadenosine is an extraordinary compound, acting as a highly selective inhibitor of S-adenosylhomocysteine hydrolase (SAHH) within the dynamic realm of cellular biochemistry. Synonyms: 8-fluoro-adenosine; (2R,3R,4S,5R)-2-(6-Amino-8-fluoro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. CAS No. 23205-67-6. Molecular formula: C10H12FN5O4. Mole weight: 285.23. | |
| 8-hydroxyfuranocoumarin 8-O-methyltransferase | Converts xanthotoxol into xanthotoxin, which has therapeutic potential in the treatment of psoriasis as it has photosensitizing and antiproliferative activities. Methylates the 8-hydroxy group of some hydroxy- and methylcoumarins, but has little activity on non-coumarin phenols (see also EC 2.1.1.69, 5-hydroxyfuranocoumarin 5-O-methyltransferase). Group: Enzymes. Synonyms: furanocoumarin 8-methyltransferase; furanocoumarin 8-O-methyl-transferase; xanthotoxol 8-O-methyltransferase; XMT; 8-hydroxyfuranocoumarin 8-O-methyltransferase; SAM:xanthotoxol O-methyltransferase; S-adenosyl-L-methionine:8-hydroxyfuranoco. Enzyme Commission Number: EC 2.1.1.70. CAS No. 67339-13-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1972; 8-hydroxyfuranocoumarin 8-O-methyltransferase; EC 2.1.1.70; 67339-13-3; furanocoumarin 8-methyltransferase; furanocoumarin 8-O-methyl-transferase; xanthotoxol 8-O-methyltransferase; XMT; 8-hydroxyfuranocoumarin 8-O-methyltransferase; SAM:xanthotoxol O-methyltransferase; S-adenosyl-L-methionine:8-hydroxyfuranocoumarin 8-O-methyltransferase; xanthotoxol methyltransferase; xanthotoxol O-methyltransferase; S-adenosyl-L-methionine:xanthotoxol O-methyltransferase; S-adenosyl-L-methionine-xanthotoxol O-methyltransferase. Cat No: EXWM-1972. | |
| 8-hydroxyquercetin 8-O-methyltransferase | Also acts on 8-hydroxykaempferol, but not on the glycosides of 8-hydroxyflavonols. An enzyme from the flower buds of Lotus corniculatus. Group: Enzymes. Synonyms: flavonol 8-O-methyltransferase; flavonol 8-methyltransferase; S-adenosyl-L-methionine:3,3',4',5,7,8-hexahydroxyflavone 8-O-methyltransferase; 8-hydroxyquercitin 8-O-methyltransferase [mis-spelt]. Enzyme Commission Number: EC 2.1.1.88. CAS No. 99775-17-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1989; 8-hydroxyquercetin 8-O-methyltransferase; EC 2.1.1.88; 99775-17-4; flavonol 8-O-methyltransferase; flavonol 8-methyltransferase; S-adenosyl-L-methionine:3,3',4',5,7,8-hexahydroxyflavone 8-O-methyltransferase; 8-hydroxyquercitin 8-O-methyltransferase [mis-spelt]. Cat No: EXWM-1989. | |
| acyl-homoserine-lactone synthase | Acyl-homoserine lactones (AHLs) are produced by a number of bacterial species and are used by them to regulate the expression of virulence genes in a process known as quorum-sensing. Each bacterial cell has a basal level of AHL and, once the population density reaches a critical level, it triggers AHL-signalling which, in turn, initiates the expression of particular virulence genes. N-(3-Oxohexanoyl)-[acyl-carrier protein] and hexanoyl-[acyl-carrier protein] are the best substrates. The fatty-acyl substrate is derived from fatty-acid biosynthesis through acyl-[acyl-carrier protein] rather than from fatty-acid degradation through acyl-CoA. S-Adenosyl-L-methionine cannot be rep...No. 176023-66-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2126; acyl-homoserine-lactone synthase; EC 2.3.1.184; 176023-66-8; acyl-homoserine lactone synthase; acyl homoserine lactone synthase; acyl-homoserinelactone synthase; acylhomoserine lactone synthase; AHL synthase; AHS; AHSL synthase; AhyI; AinS; AinS protein; autoinducer synthase; autoinducer synthesis protein rhlI; EsaI; ExpISCC1; ExpISCC3065; LasI; LasR; LuxI; LuxI protein; LuxM; N-acyl homoserine lactone synthase; RhlI; YspI acyl-[acyl carrier protein]:S-adenosyl-L-methionine acyltranserase (lactone-forming, methylthioadeno | |
| Ademethionine 1,4-Butanedisulfonate | Ademethionine 1,4-Butanedisulfonate is used in the synthesis of sulfonio-adenosyl-L-methionine (SAMe) salts. Synonyms: (3S)-5'-[(3-Amino-3-carboxypropyl)methylsulfonio]-5'-deoxyadenosine 1,4-Butanedisulfonate 1,4-Butanedisulfonate (2:1:2); 1,4-Butanedisulfonic Acid, ion(2-)Bis[(3S)-5'-[(3-amino-3-carboxypropyl)methylsulfonio]-5'-deoxyadenosine] 1,4-Butanedisulfonate (1:2); 1,4-Butanedisulfonic Acid Ion(2-), Bis[5'-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5'-deoxyadenosine], 1,4-Butanedisulfonate (1:2); SAMe-1,4-Butanedisulfonate; S-Adenosylmethione-1,4-butanedisulfonate. Grades: 95%. CAS No. 101020-79-5. Molecular formula: C19H33N6O11S3 1/2(C4H8O6S2). Mole weight: 617.69. | |
| Ademethionine Disulfate Tosylate | Ademetionine Disulfate Tosylate is used to study the survival time in various damage brain models. Synonyms: 4-Methylbenzenesulfonate (salt) Sulfate (salt) (1:1:1:1) (9CI); FO 1561; S-Adenosyl-L-methionine Disulfate Tosylate; 5'-[[(3S)-3-Amino-3-carboxypropyl]methylsulfonio]-5'-deoxyadenosine Sulfate 4-Methylbenzenesulfonate Sulfate; (3S)-5'-[(3-Amino-3-carboxyp. Grades: > 95%. CAS No. 97540-22-2. Molecular formula: C22H34N6O16S4. Mole weight: 766.8. | |
| Ademetionine | Ademetionine is a common co-substrate involved in methyl group transfers. Applications: A common co-substrate involved in methyl group transfers. Group: Coenzymes. Synonyms: S-Adenosyl-L-methionine; SAMe; AdoMet. CAS No. 29908-03-0. Purity: ≥95%. Mole weight: 398.44. Form: Solid. S-Adenosyl-L-methionine; SAMe; AdoMet; Ademetionine; 29908-03-0. Cat No: COEC-097. | |
| Ademetionine 1,4-butanedisulfonate | Heterocyclic Organic Compound. Alternative Names: (3s)-5-[(3-amino-3-carboxypropyl)methylsulfonio]-5-deoxy-adenosine 1,4-butanedisulfonate 1,4-butanedisulfonate (2:1:2);Ademetionine 1,4-butanedisulfonate;s-adenosylmethionine 1,4-butanedisulfonate;Adenosine, 5-(3S)-3-amino-3-carboxypropylmethylsulfonio-5-deoxy-, 1,4-butanedisulfonate (salt), 1,4-butanedisulfonate (salt) (2:1:2);S-ADENOSYLMETHIONINE1,4-BUTANEDUSULFONATE;(3S)-5-[(3-Amino-3-carboxypropyl)methylsulfonio]-5-deoxy-adenosine 1,4-butanedisulfonate 1,4-butanedisulfonate (2:1:2);S-Adenosylmethione-1,4-butanedisulfonate;S-Adenosyl-L-methionine 1,4-butanedisulfonate sodium salt. CAS No. 101020-79-5. Molecular formula: 2C15H23N6O5S.2C4H10O6S2.C4H8O6S2. Mole weight: 1451.63. Purity: 0.98. Catalog: ACM101020795. | |
| Adenosine dialdehyde | Adenosine dialdehyde is an irreversible inhibitor of S-adenosylhomocysteine hydrolase (IC50 = 40 nM), blocking the conversion of SAH to homocysteine and adenosine. Synonyms: 2-[1-(6-aminopurin-9-yl)-2-oxoethoxy]-3-hydroxypropanal. Grades: ≥ 95 %. CAS No. 34240-05-6. Molecular formula: C10H11N5O4. Mole weight: 265.23. | |
| adenosyl-fluoride synthase | The fluorinase enzyme (EC 2.5.1.63, also known as adenosyl-fluoride synthase) catalyzes the reaction between fluoride ion and the co-factor S-adenosyl-L-methionine to generate L-methionine and 5'-fluoro-5'-deoxyadenosine, the first committed product of the fluorometabolite biosynthesis pathway. Group: Enzymes. Synonyms: fluorinase. Enzyme Commission Number: EC 2.5.1.63. CAS No. 438583-16-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2801; adenosyl-fluoride synthase; EC 2.5.1.63; 438583-16-5; fluorinase. Cat No: EXWM-2801. | |
| adenosylhomocysteinase | The enzyme contains one tightly bound NAD+ per subunit. This appears to bring about a transient oxidation at C-3' of the 5'-deoxyadenosine residue, thus labilizing the thioether bond (for mechanism, click here), cf. EC 5.5.1.4, inositol-3-phosphate synthase. Group: Enzymes. Synonyms: S-adenosylhomocysteine synthase; S-adenosylhomocysteine hydrolase (ambiguous); adenosylhomocysteine hydrolase; S-adenosylhomocysteinase; SAHase; AdoHcyase. Enzyme Commission Number: EC 3.3.1.1. CAS No. 9025-54-1. AHCY. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3992; adenosylhomocysteinase; EC 3.3.1.1; 9025-54-1; S-adenosylhomocysteine synthase; S-adenosylhomocysteine hydrolase (ambiguous); adenosylhomocysteine hydrolase; S-adenosylhomocysteinase; SAHase; AdoHcyase. Cat No: EXWM-3992. | |
| Adenosylhomocysteinase | Adenosylhomocysteinase (SAHH; AHCY) is a highly conserved enzyme. Adenosylhomocysteinase reversible catalyzes S-adenosylhomocysteine (SAH) to adenosine and L-homocysteine. The serum exosomal Adenosylhomocysteinase level can be used as a prognostic biomarker in HBV-LC patients [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: SAHH; AHCY. CAS No. 9025-54-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-149048. | |
| Adenosylhomocysteinease from Human, Recombinant | S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Adenosylhomocysteinase is an enzyme that converts S-adenosylhomocysteine to homocysteine and adenosine. This enzyme catalyses the following chemical reaction: S-adenosyl-L-homocysteine + H2O<-> L-homocysteine + adenosine. The enzyme contains one tightly bound NAD+ per subunit. Group: Enzymes. Synonyms: Adenosylhomocysteinase; S-adenosylhomocysteine synthase; S-adenosylhomocysteine hydrolase; adenosylhomocysteine hydr. Enzyme Commission Number: EC 3.3.1.1. CAS No. 9025-54-1. AHCY. Mole weight: 47 kDa. Storage: -20°C. Form: Purified and lyophilized powder or Purified, solution in 50% glycerol. Source: Human. Adenosylhomocysteinase; S-adenosylhomocysteine synthase; S-adenosylhomocysteine hydrolase; adenosylhomocysteine hydrolase ambiguous; S-adenosylhomocysteinase; SAHase; AdoHcyase; EC 3.3.1.1; 9025-54-1; AHCY. Cat No: DIA-122. | |
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