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| Product | Description | |
|---|---|---|
| SF 11 | SF 11. Group: Biochemicals. Grades: Purified. CAS No. 443292-81-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| SF 11 | SF 11 is a potent and brain penetrant neuropeptide Y Y2 receptor antagonist ( IC 50 =199 nM). Antidepressant-like activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 443292-81-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107731. |  |
| SF 11 | SF 11 is a selective and brain penetrating neuropeptide Y (NPY) Y2 antagonist (IC50 = 199 nM) displaying no affinity for Y1 receptor at concentrations up to 35 μM. SF 11 causes significant lethality in mice. Synonyms: SF 11; SF11; SF-11; N-(4-Ethoxyphenyl)-4-(hydroxydiphenylmethyl)-1-piperidinecarbothioamide. Grades: ≥99% by HPLC. CAS No. 443292-81-7. Molecular formula: C27H30N2O2S. Mole weight: 446.6. |  |
| SF 1126 | SF 1126. Group: Biochemicals. Alternative Names: N2-[1,4-Dioxo-4-[[4-(4-oxo-8-phenyl-4H-1-benzopyran-2-yl)morpholinium-4-yl]methoxy]butyl]-L-arginylglycyl-L-α-aspartyl-L-serine Inner Salt. Grades: Highly Purified. CAS No. 936487-67-1. Pack Sizes: 1mg. Molecular Formula: C39H48N8O14, Molecular Weight: 852.84. US Biological Life Sciences. | Worldwide |
| K252a (2,3,9,10,11,12-Hexahydro-10-hydroxy-9-methyl-1-oxo-(9S,10R,12R)-9,12-epoxy-1H-diindolo[1,2,3-fg:3,2,1-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic Acd Methyl Ester, Antibiotic K252a, Antibiotic SF 2370, SF 2370) | K252a is an alkaloid isolated from Nocardiopsis sp. soil fungi. This compound is a highly potent cell permeable CaM Kinase II inhibitor (IC50=1.8nM). At higher concentrations it also inhibits broad spectrum of protein kinases (1-8). It is an excellent research tool of NGF receptors-trk-signal transduction due to its potent inhibition of trk-NGF receptor-tyrosine kinase activity. Group: Biochemicals. Alternative Names: 2,3,9,10,11,12-Hexahydro-10-hydroxy-9-methyl-1-oxo-(9S,10R,12R)-9,12-epoxy-1H-diindolo[1,2,3-fg:3,2,1-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic Acd Methyl Ester; Antibiotic K252a; Antibiotic SF 2370; SF 2370. Grades: Highly Purified. CAS No. 97161-97-2. Pack Sizes: 500ug, 5mg. US Biological Life Sciences. | Worldwide |
| SF1126 | SF1126 is a water soluble, small-molecule prodrug containing the pan-PI3K/mTOR inhibitor LY294002/SF1101 conjugated to the RGD-containing tetra-peptide SF1174 with potential antineoplastic and antiangiogenic activities. The targeting peptide SF1174 moiety of pan-PI3K/mTOR inhibitor SF1126 selectively binds to cell surface integrins and, upon cell entry, the agent is hydrolyzed to the active drug SF1101; SF1101 selectively inhibits all isoforms of phosphoinositide-3-kinase (PI3K) and other members of the PI3K superfamily, such as the mammalian target of rapamycin (mTOR) and DNA-PK. By inhibiting the PI3K signaling pathway, this agent may inhibit tumor cell and tumor endothelial cell proliferation and survival. Integrins are transmembrane cell adhesion proteins expressed on the surfaces of endothelial and tumor cells. Synonyms: SF 1126, SF-1126. CAS No. 936487-67-1. Molecular formula: C39H48N8O14. Mole weight: 852.84. | |
| 3,5-Dibromobenzoic acid | 3,5-Dibromobenzoic acid. Group: Dendrimer building blocks. CAS No. 618-58-6. Product ID: 3,5-dibromobenzoic acid. Molecular formula: 279.91g/mol. Mole weight: C7H4Br2O2. C1=C(C=C(C=C1Br)Br)C(=O)O. InChI=1S/C7H4Br2O2/c8-5-1-4 (7 (10)11)2-6 (9)3-5/h1-3H, (H, 10, 11). SFTFNJZWZHASAQ-UHFFFAOYSA-N. |  |
| 4- (2-morpholinoethylcarbamoyl) phenylboronic acid | 4- (2-morpholinoethylcarbamoyl) phenylboronic acid. Group: Salt. Product ID: [4-(2-morpholin-4-ylethylcarbamoyl)phenyl]boronic acid. Molecular formula: 278.11g/mol. Mole weight: C13H19BN2O4. B(C1=CC=C(C=C1)C(=O)NCCN2CCOCC2)(O)O. InChI=1S/C13H19BN2O4/c17-13 (11-1-3-12 (4-2-11) 14 (18) 19) 15-5-6-16-7-9-20-10-8-16/h1-4, 18-19H, 5-10H2, (H, 15, 17). SFJAUBYTKBOMQG-UHFFFAOYSA-N. | |
| 4-methoxycarbonyl-2-nitrophenylboronic acid | 4-methoxycarbonyl-2-nitrophenylboronic acid. Group: Salt. Product ID: (4-methoxycarbonyl-2-nitrophenyl)boronic acid. Molecular formula: 224.97g/mol. Mole weight: C8H8BNO6. B (C1=C (C=C (C=C1)C (=O)OC)[N+] (=O)[O-]) (O)O. InChI=1S/C8H8BNO6/c1-16-8 (11)5-2-3-6 (9 (12)13)7 (4-5)10 (14)15/h2-4, 12-13H, 1H3. SFEJGHJCGQNFQC-UHFFFAOYSA-N. | |
| 5(6)-SFX SE | 5(6)-SFX SE. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5(6)-FAM-X SE , Fluorescein-5(6)-carboxamidocaproic acid N-succinimidyl ester , 6-(Fluorescein-5(6)-carboxamido)hexanoic acid N-succinimidyl ester. Product Category: Fluorescein Fluorophores. Appearance: Yellow to orange powder. CAS No. 114616-31-8. Molecular formula: C31H26N2O10. Mole weight: 586.55. Purity: 90%+. Product ID: ACM114616318. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 5(6)-SFX ,SE | 5(6)-SFX ,SE (Compound SFX-SE) is a fluorescent dye for labeling primary amines and nascent proteins [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 114616-31-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-D1109. | |
| 6-Ethoxy-5-methylpyridine-3-boronic acid | 6-Ethoxy-5-methylpyridine-3-boronic acid. Group: Salt. Product ID: (6-ethoxy-5-methylpyridin-3-yl)boronic acid. Molecular formula: 181g/mol. Mole weight: C8H12BNO3. B(C1=CC(=C(N=C1)OCC)C)(O)O. InChI=1S/C8H12BNO3/c1-3-13-8-6 (2)4-7 (5-10-8)9 (11)12/h4-5, 11-12H, 3H2, 1-2H3. SFGDPXBBFQWHEF-UHFFFAOYSA-N. | |
| 9(Z),11(E)-Conjugated linoleic acid methyl ester | 9(Z),11(E)-Conjugated linoleic acid methyl ester (9Z,11E-CLA; Methyl 9(Z),11(E)-octadecadienoate; (9Z,11E)-SFE 19:2) is an isomer of Linoleic acid (HY-N0729). Conjugated linoleic acid is a bioactive fatty acid, which can improve body composition, enhance immune system function, exhibits anti-cancer and antiatherosclerosis effect [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 9Z,11E-CLA; Methyl 9(Z),11(E)-octadecadienoate; (9Z,11E)-SFE 19:2. CAS No. 13058-52-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-124370. | |
| CB-7921220 | CB-7921220 is an adenylate cyclase inhibitor which is selective, reducing adenylyl cyclase type I and VI activity by 60% while having no effect on types II and V in Sf9 membranes stimulated by forskolin at a concentration of 100 μM. CB-7921220 has a binding conformation similar to ATP and P-site inhibitors, which may explain its lack of selectivity between AC1 and AC6. Synonyms: CB7921220; CB 7921220; CB-7921220; 6-[(E)-2-(4-aminophenyl)ethenyl]pyridine-2-carboxylic acid. CAS No. 115453-99-1. Molecular formula: C14H12N2O2. Mole weight: 240.26. | |
| Flavoglaucin | Flavoglaucin is a natural compound isolated from marine fungus Eurotium sp. SF-5989. Flavoglaucin exhibits significant inhibitory effect on PTP1B with IC50 value of 13.4 micrometer. Flavoglaucin shows good binding affinity for human opioid or cannabinoid receptors. Flavoglaucin has anti-inflammatory effect, which inhibits inflammatory mediators via the induction of heme oxygenase-1 in lipopolysaccharide-stimulated RAW264.7 macrophages. Flavoglaucin exhibits significant radical scavenging activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH) with the IC50 value of 11.3 microM. Synonyms: 6-Heptyl-3-(3-methyl-2-butenyl)gentisaldehyde; Benzaldehyde, 2-heptyl-3,6-dihydroxy-5-(3-methyl-2-butenyl)-. Grades: 98.0%. CAS No. 523-73-9. Molecular formula: C19H28O3. Mole weight: 304.42. | |
| K252a | K252a. Group: Biochemicals. Alternative Names: 2,3,9,10,11,12-Hexahydro-10-hydroxy-9-methyl-1-oxo-(9S,10R,12R)-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acd methyl ester; Antibiotic K252a; Antibiotic SF 2370. Grades: Highly Purified. CAS No. 97161-97-2. Pack Sizes: 1mg, 2mg, 5mg. Molecular Formula: C27H21N3O5. US Biological Life Sciences. | Worldwide |
| N-(4-Ethoxyphenyl)-4-(hydroxydiphenylmethyl)-1-piperidinecarbothioamide | N-(4-Ethoxyphenyl)-4-(hydroxydiphenylmethyl)-1-piperidinecarbothioamide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-(4-ethoxyphenyl)-4-[hydroxy(diphenyl)methyl]piperidine-1-carbothioamide, 443292-81-7, AC1MGIEX, BAS 01915526, Oprea1_641933, MLS000569101, CHEMBL1543306, CTK8E8153, MolPort-001-556-550, HMS2560N17, ML075, SF 11, SF-11, STK077599, ZINC08687060, AKOS000589821, MCULE-1790587705, SID 17507305, SMR000177227, ST4097488. Product Category: Heterocyclic Organic Compound. CAS No. 443292-81-7. Molecular formula: 446.6. Purity: >99 %. IUPACName: N-(4-ethoxyphenyl)-4-[hydroxy(diphenyl)methyl]piperidine-1-carbothioamide. Canonical SMILES: CCOC1=CC=C(C=C1)NC(=S)N2CCC(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O. Product ID: ACM443292817. Alfa Chemistry ISO 9001:2015 Certified. | |
| Octa methyl cyclotetrasiloxane | Octa methyl cyclotetrasiloxane. Group: Biochemicals. Alternative Names: 2, 2, 4, 4, 6, 6, 8, 8-Octa methyl cyclotetrasiloxane; Abil K 4; Cyclic dimethylsiloxane tetramer; D 4; DC 244; DC 344; DC 5258; DWQ 110; DWQ 120; Dabco DC 5258; Dow Corning 244; Dow Corning 244 Fluid; Dow Corning 344; KF 994; LS 8620; Mirasil CM 4; NSC 345674; NUC Silicone VS 7207; Octa methyl cyclotetrasiloxanes; PMX 0110; SF 1173; SH 244; SH 244 Fluid; SH 344; Silbione 70045V2; Silbione V 2; TSF 404; Tetracyclomethicone; UC 7207; Union Carbide 7207; VS 7207; Volasil 244; XF 3803; Y 7175; YF 393; ZBH 270. Grades: Highly Purified. CAS No. 556-67-2. Pack Sizes: 5g. Molecular Formula: C8H24O4Si4, Molecular Weight: 296.62. US Biological Life Sciences. | Worldwide |
| PDE4A10 active from Human, Recombinant | Human PDE4A10, also known as PDE4A protein isoform 6, transcript variant 3 (GenBank Accession No. NM_001111309) amino acids 2-825 (end) with N-terminal GST-tag, MW=117 kDa, expressed in a Baculovirus infected Sf9 cell expression system. Uman pde4a10, also known as pde4a protein isoform 6, transcript variant 3 (genbank accession no. nm_001111309) amino acids 2-825 (end) with n-terminal gst-tag, mw=117 kda, expressed in a baculovirus infected sf9 cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: DPDE2; PDE46; phosphodiesterase 4A, cAMP-specific; PDE4A10; PDE4A. Purity: > 75% (SDS-PAGE). Phosphodiesterase. Mole weight: mol wt 117 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Human. DPDE2; PDE46; phosphodiesterase 4A, cAMP-specific; PDE4A10; PDE4A. Cat No: NATE-0523. |  |
| PDE4D7 active from Human, Recombinant | Human PDE4D7 (GenBank Accession No. NM_001165899) amino acids 2-748 (end) with N-terminal GST-tag, MW=111 kDa, expressed in a Baculovirus infected Sf9 cell expression system. Human pde4d7 (genbank accession no. nm_001165899) amino acids 2-748 (end) with n-terminal gst-tag, mw=111 kda, expressed in a baculovirus infected sf9 cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: DPDE3; PDE43; STRK1; phosphodiesterase 4D, cAMP-specific; PDE4D2; PDE4D. Purity: > 65% (SDS-PAGE). PDE. Mole weight: mol wt 111 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Human. DPDE3; PDE43; STRK1; phosphodiesterase 4D, cAMP-specific; PDE4D2; PDE4D. Cat No: NATE-0526. | |
| Phosphodiesterase 5A1 from Human, Recombinant | PDE5 regulates vascular smooth muscle contraction and is involved in NO-cGMP signaling in platelets to control aggregation. PDE5 may also be involved in the regulation of cGMP signaling in the brain and may modulate pressure-induced cardiac hypertrophy and fibrosis. N-terminal gst-tagged 126 kda full-length protein. Applications: Phosphodiesterase (pde) is an enzyme that is used to breaks phosphodiester bonds. pde5 is a molecular target for the treatment of erectile dysfunction and pulmonary hypertension. pde5 is used to find novel pde5 inhibitors. Group: Enzymes. Synonyms: CN5N; phosphodiesterase 5A, cGMP-specific; PDE5A1; PDE5A; 3',5'-cyclic-GMP phosphodiesterase, PDE 5A1. Phosphodiesterase. Mole weight: 126 kDa. Storage: -70°C. Form: Supplied as a solution in 20% glycerol containing 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% TWEEN 20 and 3 mM DTT. Source: Sf9 cells. Species: Human. CN5N; phosphodiesterase 5A, cGMP-specific; PDE5A1; PDE5A; 3',5'-cyclic-GMP phosphodiesterase, PDE 5A1. Cat No: NATE-0527. | |
| Pimaricin | from Streptomyces chattanoogensis, ?95% (HPLC). Group: Pesticides & metabolites standardspharma & vet compounds & metabolitesstandards for environmental regulatory methodspharma & vet compounds & metabolites. Alternative Names: Natamax lactose, 6,11,28-Trioxatricyclo[22.3.1.05,7]octacosane, pimaricin deriv., Myprozine,6,11,28-Trioxatricyclo[22.3.1.05,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid, 22-[(3-amino-3,6-dideoxy-?-D-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-, (1R,3S,5R,7R,8E,12R,14E,16E,18E,20E,22R,24S,25R,26S)-, [1R-(1R*,3S*,5R*,7R*,8E,12R*,14E,16E,18E,20E,22R*,24S*,25R*,26S*)]-22-[(3-Amino-3,6-dideoxy-?-D-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-6,11,28-trioxatricyclo[22.3.1.05,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid, Antibiotic A 5283, Delvocid, Pimaricin (6CI,8CI), 6,11,28-Trioxatricyclo[22.3.1.05,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid, 22-[(3-amino-3,6-dideoxy-?-D-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-, [1R-(1R*,3S*,5R*,7R*,8E,12R*,14E,16E,18E,20E,22R*,24S*,25R*,26S*)]-, CL 12625, Natacyn, Natamax, Pimafucin, Natamax SF, Natajen, Natamycin, E 235, Synogil, Mycophyt, Myuprozine, ?-Natamycin, Tennecetin (7CI). |  |
| Pyrindamycin A | Pyrindamycin A is an antibiotic produced by the strain of Streptomyces spp. It inhibits DNA synthesis and has the activity against gram-positive and gram-negative bacteria. It has antitumor activity against murine leukemia, shows stronger cytotoxic activities towards murine and human tumor cell lines and especially towards doxorubicin-resistant cells, inhibits P388 and P388/ADR cells with the same IC50 of 3.9 μg/ml. Synonyms: Duocarmycin C2; Antibiotic DC 89A2; Benzo(1,2-b:4,3-b')dipyrrole-2-carboxylic acid, 8-(chloromethyl)-1,2,3,6,7,8-hexahydro-4-hydroxy-2-methyl-1-oxo-6-((5,6,7-trimethoxy-1H-indol-2-yl)carbonyl)-, methyl ester, (2R-trans)-; Methyl (2R,8S)-8-(chloromethyl)-4-hydroxy-2-methyl-1-oxo-6-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]-1,2,3,6,7,8-hexahydropyrrolo[3,2-e]indole-2-carboxylate; Antibiotic SF 2582A. Grades: ≥95%. CAS No. 118292-36-7. Molecular formula: C26H26ClN3O8. Mole weight: 543.95. | |
| Pyrindamycin B | Pyrindamycin B is an antibiotic. It is active against gram-positive and gram-negative bacteria, and exhibits strong therapeutic effects against both drug-sensitive and resistant cells of P388 leukemia in mice. Synonyms: Pyrindamycin B; Antibiotic DC 89A1; Antibiotic SF 2582B. CAS No. 118292-35-6. Molecular formula: C26H26ClN3O8. Mole weight: 543.95. | |
| Sanglifehrin A | It is a cyclophilin combination produced by the strain of Streptomyces sp. A92-308110. The affinity of Sanglifehrin A to Cyclophilin is 10-20 times stronger than Cyclosporin A. The immunosuppressive effect of Sanglifehrin is lower than Cyclosporin A by mixed lymphocyte reaction assay. Synonyms: SFA; (-)-sanglifehrin A; 19-Oxa-1,4,7,25-tetraazabicyclo[19.3.1]pentacosa-13,15-diene-2,5,8,20-tetrone, 18-[(1E,3E,7S,8S)-9-[(2S,3R,4S,5S,6R,9S,11S)-9-ethyl-4-hydroxy-3,5,11-trimethyl-8-oxo-1-oxa-7-azaspiro[5.5]undec-2-yl]-8-hydroxy-1,7-dimethyl-1,3-nonadienyl]-10,12-dihydroxy-3-[(3-hydroxyphenyl)methyl]-11-methyl-6-(1-methylethyl)-9-(3-oxobutyl)-, (3S, 6S, 9R, 10R, 11S, 12S, 13E, 15E, 18S, 21S)-. CAS No. 187148-13-6. Molecular formula: C60H91N5O13. Mole weight: 1090.39. | |
| Sanglifehrin C | It is a cyclophilin combination produced by the strain of Streptomyces sp. A92-308110. The affinity of Sanglifehrin C to Cyclophilin is similar to Cyclosporin A. The immunosuppressive effect of Sanglifehrin is lower than Cyclosporin A by mixed lymphocyte reaction assay. Synonyms: SFC. Molecular formula: C61H93N5O13. Mole weight: 1104.41. | |
| SF 2315 A | SF 2315 A is a quinone antibiotic produced by Excellospora viridilutea SF2315. It exhibits inhibitory effect against Avian myelobastosis virus reverse transcriptase with IC50 of 100 μg/mL. It has weak activity against gram-positive bacteria. Synonyms: Antibiotic SF 2315A; SF 2315A; SF2315A; cis-(+)-4a,5,6,12b-Tetrahydro-4a,8-dihydroxy-3-methylbenz(a)anthracene-1,7,12(4H)-trione. CAS No. 114687-52-4. Molecular formula: C19H16O5. Mole weight: 324.3. | |
| SF 2315 B | SF 2315 B is a quinone antibiotic produced by Excellospora viridilutea SF2315. It exhibits inhibitory effect against Avian myelobastosis virus reverse transcriptase with IC50 of 40 μg/mL. It has weak activity against gram-positive bacteria. Synonyms: Antibiotic SF 2315B; SF 2315B; SF2315B. CAS No. 114687-53-5. Molecular formula: C19H20O5. Mole weight: 344.4. | |
| SF-2415A1 | SF-2415A1 is an antibiotic produced by Streptomyces aculeolatus. It is effective against gram-positive bacteria but inactive to gram-negative bacteria. Synonyms: Antibiotic SF 2415A1; SF 2415A1. CAS No. 110200-32-3. Molecular formula: C26H31ClN2O5. Mole weight: 487. | |
| SF-2415A2 | SF-2415A2 is an antibiotic produced by Streptomyces aculeolatus. It is effective against gram-positive bacteria but inactive to gram-negative bacteria. Synonyms: Antibiotic SF 2415A2; SF 2415A2. CAS No. 110200-31-2. Molecular formula: C26H30N2O5. Mole weight: 450.5. | |
| SF-2415A3 | SF-2415A3 is an antibiotic produced by Streptomyces aculeolatus. It is effective against gram-positive bacteria but inactive to gram-negative bacteria. Synonyms: Antibiotic SF 2415A3; SF 2415A3. CAS No. 110200-33-4. Molecular formula: C26H30Cl2N2O5. Mole weight: 521.4. | |
| SF-2415B1 | SF-2415B1 is an antibiotic produced by Streptomyces aculeolatus. It is effective against gram-positive bacteria but inactive to gram-negative bacteria. Synonyms: Antibiotic SF 2415B1; SF 2415B1. CAS No. 110200-34-5. Molecular formula: C26H33ClO5. Mole weight: 461. | |
| SF 2446A3 | Synonyms: SF2446A3. CAS No. 115834-24-7. Molecular formula: C26H21NO11. Mole weight: 523.4. | |
| SF2457 | SF2457 is an antibiotic related to amicetin, which is isolated from the fermentation broth of Nocardia brasiliensis SF2457. It exhibits inhibitory activity against Gram-positive and Gram-negative bacteria. Synonyms: SF-2457; SF 2457. CAS No. 115748-04-4. Molecular formula: C27H38N6O9. Mole weight: 590.6. | |
| SF2523 | SF2523 is a dual inhibitor of phosphatidylinositol 3-kinase and bromodomain-containing protein 4 with IC50 values of 34 nM, 158 nM, 9 nM, 241 nM and 280 nM for PI3Kα, PI3Kγ, DNA-PK, BRD4 and mTOR, respectively. In vivo SF2523 shows anti- tumor activity in xenograft studies. Synonyms: 3-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-morpholin-4-ylthieno[3,2-b]pyran-7-one; SF-2523; SF 2523; CHEMBL2322228. CAS No. 1174428-47-7. Molecular formula: C19H17NO5S. Mole weight: 371.41. | |
| SfaN I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme more than 95% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 500 U; 2500U. GCATC(N)5↑ CGTAG(N)9&darr. Activity: 10000u.a./ml. Appearance: 10 X SE-buffer O. Storage: -20°C. Form: Liquid. Source: An E.coli strain that carries the cloned SfaN I gene from Streptococcus faecalis N. Pack: 10 mM Tris-HCl (pH 7.5); 300 mM NaCl; 0,1 mM EDTA; 1 mM DTT; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1172RE. | |
| Sfi I | One unit of the enzyme is the amount required to hydrolyze 1 μg of T7 DNA in 1 hour at 50°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme more than 70% of the dna fragments can be ligated and recut. in the presence of 10% peg ligation is better. Group: Restriction Enzymes. Purity: 1000U; 5000U. GGCCNNNN↑NGGCC CCGGN↓NNNNCCGG. Activity: 10000u.a./ml. Appearance: 10 X SE-buffer G, BSA. Storage: -20°C. Form: Liquid. Source: An E.coli strain, that carries the cloned gene Sfi I from Streptomyces fimbriatus. Pack: 10 mM Tris-HCl (pH 7.5); 200 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1173RE. | |
| Sibanomicin | It is produced by the strain of Micronconospora sp. SF2364. It has weak effect against gram-positive bacteria. Mice inoculated with leukemic P388 cells were given 2.1 and 1.0 mg/kg, which extended the survival time by 96% and 69% compared with the control group. Synonyms: 7-[[3-C-Methyl-4-(methylamino)-4,6-dideoxy-α-L-mannopyranosyl]oxy]-1,2,3,11a-tetrahydro-2-[(E)-propylidene]-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one; 5H-Pyrrolo[2,1-c][1,4]benzodiazepin-5-one, 7-[[4,6-dideoxy-3-C-methyl-4-(methylamino)-a-L-mannopyranosyl]oxy]-1,2,3,11a-tetrahydro-2-propylidene-, (2E)-; Antibiotic SF 2364. CAS No. 117782-84-0. Molecular formula: C23H31N3O5. Mole weight: 429.51. | |
| Tallowamine polyethoxylated | Tallowamine polyethoxylated. Uses: For analytical and research use. Group: Food contact materials. Alternative Names: Rhodameen T 15, Ethomeen T 27, Genamin T, Genamin T 200NF, Witcamine TAM 45, Katapol PN 430, Ethoxylated tallow amines, Ethoxamine SF 11, Rhodameen IT 50/46, Rhodameen T 50, MON 0818, Nymeen T 2-202, Surfonic T 20, Prevocell 1618/3, T 15, Surfonic T 5, Varonic T 220, Amiet 502, Atlas G 3780644, Trymeen 6607, Surfonic T 15, Genamin T 080, Nissan Nymeen T 2-210, Alkaminox T 2, Genamin T 020, Entry I. CAS No. 61791-26-2. Catalog: APS61791262. Format: Neat. Shipping: Room Temperature. | |
| tert-Butyl(3>R,4S)-3-fluoro-4-hydroxypiperidine-1-carboxylate | tert-Butyl(3>R,4S)-3-fluoro-4-hydroxypiperidine-1-carboxylate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1174020-42-8, tert-butyl (3R,4S)-3-fluoro-4-hydroxypiperidine-1-carboxylate, (3R,4S)-tert-butyl 3-fluoro-4-hydroxypiperidine-1-carboxylate, SCHEMBL255934, XRNLYXKYODGLMI-SFYZADRCSA-N, WT1084, ZINC32915018, SS-4802, AJ-85709, AK170547, DB-061012, KB-309050, I12-0524, tert-butyl cis-3-fluoro-4-hydroxypiperidine-1-carboxylate, (cis)-3-fluoro-4-hydroxypiperidine-1-carboxylic acid tert-butyl ester, tert-butyl (3R,4S)-3-fluoro-4-hydroxypiperidine-1-carboxylate >98% ee, 1174020-42-8 tert-butyl (3R,4S)-3-fluoro-4-hydroxypiperidine-1-carboxylate. Product Category: Heterocyclic Organic Compound. CAS No. 1174020-42-8. Molecular formula: C10H18FNO3. Mole weight: 219.253223 [g/mol]. Purity: 0.96. IUPACName: tert-butyl (3R,4S)-3-fluoro-4-hydroxypiperidine-1-carboxylate. Canonical SMILES: CC(C)(C)OC(=O)N1CCC(C(C1)F)O. Product ID: ACM1174020428. Alfa Chemistry ISO 9001:2015 Certified. | |
| SF1670 | SF1670 is a highly potent and specific PTEN inhibitor with IC50 of 2 μM. Synonyms: SF1670; SF 1670; SF-1670. Grades: >98%. CAS No. 345630-40-2. Molecular formula: C19H17NO3. Mole weight: 307.34. | |
| SF-331 | SF-331 is one of diaminoaryl-triazinenitrofurylhydrazones with an inhibitory effect on mycobacterium tuberculosis. Uses: Antibacterial agent. Synonyms: SF331; SF 331. | |
| SF-PDI | Band gap: 2.1 eV. Group: Organic field effect transistor (ofet) materials organic solar cell (opv) materials. Alternative Names: 1-(3-Butoxycarbonylpropyl)-1-phenyl-[6.6]C61. CAS No. 1643842-69-6. Pack Sizes: 100 mg in glass bottle. Molecular formula: 1822.44. Mole weight: C125H136N4O8. O=C1N (C (CCCCCC) CCCCCC) C (C2=C (C1=CC=C3C4=C (C (C=C5) =CC6=C5C (C=CC (C7=CC8=C9C% 10=C7C% 11=C% 12C (C% 13=CC=C% 12C% 10=CC=C9C (N (C (CCCCCC) CCCCCC) C8=O) =O) =C (C (N (C (CCCCCC) CCCCCC) C% 13=O) =O) C=C% 11) =C% 14) =C% 14C6% 15C% 16=CC=CC=C% 16C% 17=C% 15C=CC=C% 17) C=C (C (N (C (CCCCCC) CCCCCC) C. InChI=1S / C125H136N4O8 / c1-9-17-25-33-45-79 (46-34-26-18-10-2) 126-117 (130) 93-67-61-87-89-63-69-97-113-101 (123 (136) 128 (121 (97) 134) 81 (49-37-29-21-13-5) 50-38-30-22-14-6) 75-99 (109 (115 (89) 113) 91-65-71-95 (119 (126) 132) 111 (93) 107 (87) 91) 77-57-59-85-86-60-58-78 (74-106 (86) 125 (105 (85) 73-77) 103-55-43-41-53-83 (103) 84-54-42-44-56-104 (84) 125) 100-76-102-114-98 (122 (135) 129 (124 (102) 137) 82 (51-39-31-23-15-7) 52-40-32-24-16-8) 70-64-90-88-62-68-94-112-96 (72-66-92 (108 (88) 112) 110 (100) 116 (90) 114) 120 (133) 127 (118 (94) 131) 80 (47-35-27-19-11-3) 48-36-28-20-12-4 / h41-44, 53-76, 79-82H, 9-40, 45-52H2, 1-8H3. FYQVTINZMWVMSE-UHFFFAOYSA-N. | |
| Sfr274 I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA (Hind III-digest) in 1 hour at 50°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 2000U; 10000U. C↑TCGAG GAGCT↓C. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer B. Storage: -20°C. Form: Liquid. Source: Streptomyces fradiae 274. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1174RE. | |
| Sfr303 I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. CCGC↑GG GG↓CGCC. Activity: 10000u.a./ml. Appearance: 10 X SE-buffer B. Storage: -20°C. Form: Liquid. Source: Streptomyces fradiae 303. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1175RE. | |
| VT-464 | VT-464, also called as Seviteronel, is an oral, non-steroidal, lyase-selective CYP17 inhibitor to reach Phase II clinical trials in Breast cancer in USA (PO). in vitro: Approximately 10-fold more selective towards lyase than hydroxylase. Selective inhibit. Uses: Antineoplastic agents. Synonyms: (1S)-1-[6,7-bis(difluoromethoxy)naphthalen-2-yl]-2-methyl-1-(2H-triazol-4-yl)propan-1-ol; VT464; VT 464; VT-464; INO-464; INO 464; INO464;CHEMBL3264610; CS-3139; CS 3139; CS3139; HY-15996; UNII-8S5OIN36X4 component ZBRAJOQFSNYJMF-SFHVURJKSA-N; 1610537-15-9; 1H-1,2,3-Triazole-5-methanol, alpha-(6,7-bis(difluoromethoxy). CAS No. 1610537-15-9. Molecular formula: C18H17F4N3O3. Mole weight: 399.34. | |
| VT-464 racemate | The racemate form of VT-464, a non-steroidal compound, has been found to lead to the reduction of androgen through acting as a human CYP17 lyase inhibitor. IC50: 69 nM. Uses: The racemate form of vt-464 has been found to lead to the reduction of androgen through acting as a human cyp17 lyase inhibitor. Synonyms: VT-464 racemate; VT 464 racemate; VT464 racemate; VT-464; CHEMBL3264610; CS-3139; CS 3139; CS3139; UNII-8S5OIN36X4 component ZBRAJOQFSNYJMF-SFHVURJKSA-N. Grades: 98%. CAS No. 1375603-36-3. Molecular formula: C18H17F4N3O3. Mole weight: 399.34. | |
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