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(1R,2R,3S,4S,5S)-1-(tert-Butyldiphenyl)silyloxymethyl-2,3-dioxy-O,O-isopropylidenebicyclo[3.1.0]hexan-4-ol, an innovative compound utilized in the biomedical sector, showcases promising therapeutic attributes for diverse ailments. Synonyms: (3aR,3bR,4aS,5S,5aS)-3b-[[[(1,1-Dimethylethyl)diphenylsilyl]oxy]methyl]hexahydro-2,2-dimethylcyclopropa[3,4]cyclopenta[1,2-d]-1,3-dioxol-5-ol. CAS No. 915694-38-1. Molecular formula: C26H34O4Si. Mole weight: 438.63.
2,2,3,3-tetramethyl-4,7,10,13,16,19,22-heptaoxa-3-silatetracosan-24-oic acid. Uses: Designed for use in research and industrial production. Product Category: PROTAC Library. Molecular formula: C20H42O9Si. Mole weight: 454.6276. Purity: >95%. Product ID: PR01102. Alfa Chemistry ISO 9001:2015 Certified.
2,2,3,3-tetramethyl-4,7,10,13,16,19-hexaoxa-3-silahenicosan-21-oic acid. Uses: Designed for use in research and industrial production. Product Category: PROTAC Library. Molecular formula: C18H38O8Si. Mole weight: 410.575. Purity: >96%. Product ID: PR01081. Alfa Chemistry ISO 9001:2015 Certified.
2,3,5-Tri-O-benzhydryloxybis(trimethylsilyloxy)silyl-2-C-methyl-D-ribono-1,4-lactone is an organic compound used in the synthesis of antiviral drugs, specifically for research of hepatitis C and related viral infections. Molecular formula: C63H94O14Si9. Mole weight: 1328.20.
2-Acetamido-6-O-(a-2-N-acetylneuraminyl)-2-deoxy-a-D-galactopyranosyl serine, a chemical compound with profound biomedical implications, emerges as an efficacious glycosylation inhibitor within the realms of rigorous scientific investigation. With its noteworthy potential to unravel the intricate disease pathogenesis, facilitate the creation of innovative therapeutics targeting glycosylation-related disorders, and elucidate the underlying molecular mechanisms, this product assumes great significance in advancing the realm of drug efficacy assessment. Synonyms: STn Epitope; Serinyl 2-Acetamido-2-deoxy-6-O-(α-2-N-Acetylnuraminyl)-α-D-galactopyranosyl; 6-O-α-Sialyl-2-acetamido-2-deoxy-α-D-galactopyranosyl-1-O-L-serine; O-[2-(acetylamino)-6-O-(N-acetyl-α-neuraminosyl)-2-deoxy-α-D-galactopyranosyl]-L-serine; Sialyl Tn Antigen; O-[N-acetyl-alpha-neuraminyl-(2->6)-N-acetyl-alpha-D-galactosaminyl]-L-serine; 3-O-(2-Acetamido-6-O-(N-acetylneuraminyl)-2-deoxygalactosyl)serine. Grade: ≥95%. CAS No. 114661-01-7. Molecular formula: C22H37N3O16. Mole weight: 599.54.
2'-Deoxy-2'-fluoro-3',5'-bis-O-TBDMS-uridine
2'-Deoxy-2'-fluoro-3',5'-bis-O-TBDMS-uridine is a crucial compound extensively used in biomedicine, acting as a potent nucleoside analog incorporated into RNA molecules to disrupt viral replication processes. This compound has demonstrated promising results in the reserch of RNA viruses, including SARS-CoV-2, Influenza, and Hepatitis C. Synonyms: Uridine, 2'-deoxy-3',5'-bis-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-fluoro-; 1-[(2R,3R,4R,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-[[tert-butyl(dimethyl)silyl]oxymethyl]-3-fluorooxolan-2-yl]pyrimidine-2,4-dione; 3',5'-Bis-O-Tert-Butyl(Dimethyl)Silyl)-2'-Deoxy-2'-(R)-Fluoro-Uridine. Grade: ≥95%. CAS No. 139878-36-7. Molecular formula: C21H39FN2O5Si2. Mole weight: 474.71.
2'-O-tert-Butyl(dimethyl)silyl-2-debenzoyl-[2,4]-oxol Paclitaxel is one of Paclitaxel intermediates. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Molecular formula: C46H61NO13Si. Mole weight: 864.06.
2-O-tert-Butyl(dimethyl)silyl-2-debenzoyl-[2,4]-oxol Paclitaxel is an intermediate in the synthesis of Paclitaxel (P132500) related compound. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C46H61NO13Si. US Biological Life Sciences.
(2R, 3S, 4S, 5R)-5-Hydroxy-2, 3, 4-tris (phenylmethoxy)-5-[ (phenylmethoxy)methyl]-cyclohexanone is used to explore the steric course of 5-epi-valiolone dehydratase in validamycin A biosynthesis. It can also be used to synthesize 1-Silyl-2,6-diketones as versatile intermediates for divergent synthesis of five and six-membered carbocycle cyclitols under radical and anionic conditions. Group: Biochemicals. Grades: Highly Purified. CAS No. 911439-19-5. Pack Sizes: 5mg, 50mg. Molecular Formula: C35H36O6, Molecular Weight: 552.66. US Biological Life Sciences.
3,4,6-Tri-O-acetyl-2-azido-1-O-[tert-butyl(dimethyl)silyl]-2-deoxy-beta-D-glucopyranose, an indispensable compound in the biomedical sector, showcases its significance in the synthesis of glycosidic compounds and the investigation of carbohydrate-mediated interactions. In the pursuit of antiviral drugs, focusing on restraining glycosidase enzymes to combat viral infections, this product emerges as an invaluable asset. Its multifaceted application and pivotal role render it indispensable within the realm of drug development. Synonyms: 1-O-tert-Butyldimethylsilyl 2-azido-2-deoxy-beta-D-glucopyranoside 3,4,6-triacetate; tert-Butyldimethylsilyl-3,4,6-tri-O-acetyl-2-azido-2-deoxy-ss-D-glucopyranoside. CAS No. 99049-65-7. Molecular formula: C18H31N3O8Si. Mole weight: 445.54.
Used in the preparation of follicular fluid-meiosis activating sterols (FF-MAS). Group: Biochemicals. Alternative Names: (20S)-21-O-[[Tris (isopropyll)silyl]-20-methyl-pregn-5-ene-3 β,21-diol. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
(3-Cyanobutyl)Methyldichlorosilane
(3-Cyanobutyl)Methyldichlorosilane. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (3-CYANOBUTYL)METHYLDICHLOROSILANE;4-(dichloromethylsilyl)-2-methylbutyronitrile;4-[Dichloro(methyl)silyl]-2-methylbutanenitrile. Product Category: Heterocyclic Organic Compound. CAS No. 71550-62-4. Molecular formula: C6H11Cl2NSi. Mole weight: 196.17 g/mol. Product ID: ACM71550624. Alfa Chemistry ISO 9001:2015 Certified.
3'-O-(t-Butyldimethylsilyl)-2'-O-(2-methoxyethyl)-5-methyluridine is a crucial compound in biomedicine used for various purposes. It plays a significant role in synthesizing nucleic acid analogs, and specifically, it is extensively utilized in the research and development of antiviral drugs. This compound acts as a key building block in the construction of nucleoside analogs targeting viral replication processes, facilitating the treatment of viral diseases such as HIV and hepatitis. Synonyms: 3'-O-[Dimethyl(2-methyl-2-propanyl)silyl]-2'-O-(2-methoxyethyl)-5-methyluridine; Uridine, 3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-O-(2-methoxyethyl)-5-methyl-. Grade: ≥95%. CAS No. 1221967-92-5. Molecular formula: C19H34N2O7Si. Mole weight: 430.57.
3'-O-(t-Butyldimethylsilyl)-2'-O-methyluridine
3'-O-(t-Butyldimethylsilyl)-2'-O-methyluridine is a biochemical compound widely used in the biomedical industry. This product is utilized in the development of antiviral drugs and therapies for treating viral infections such as hepatitis and HIV. Its unique properties make it a valuable tool for researchers studying nucleotide modifications and their impact on RNA function. Synonyms: Uridine, 3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-O-methyl-; 2'-O-Methyl-3'-O-(tert-butyldimethylsilyl)uridine; 1-((2R,3R,4R,5R)-4-((tert-Butyldimethylsilyl)oxy)-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 3'-O-TBDMS-2'-OMe-U; 3'-O-[Dimethyl(2-methyl-2-propanyl)silyl]-2'-O-methyluridine; 3'-TBDMS-2'-O-Me-rU. Grade: ≥95%. CAS No. 171268-84-1. Molecular formula: C16H28N2O6Si. Mole weight: 372.49.
A derivative of S. Group: Biochemicals. Alternative Names: (2S, 3R, 4E) -2-Amino-3- (tertbutyldi methyl silyloxy) -2-fluorenylcarbonylamino-4-octadecene-1-ol. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
5-O-tert-Butyldimethylsilyl-1,4-dideoxy-1,4-imino-2,3-O-isopropylidene-D-ribitol is a compound frequently employed in the biomedical sector, exhibiting remarkable potency in research of a multitude of diseases and conditions, predominantly bacterial infections. Synonyms: (3aR,4R,6aS)-4-{[(tert-butyldimethylsilyl)oxy]methyl}-2,2-dimethyl-hexahydro-[1,3]dioxolo[4,5-c]pyrrole; (3aR,4R,6aS)-4-(((tert-Butyldimethylsilyl)oxy)methyl)-2,2-dimethyltetrahydro-3aH-[1,3]dioxolo[4,5-c]pyrrole; (3aR,4R,6aS)-4-(((tert-butyldimethylsilyl)oxy)methyl)-2,2-dimethyltetrahydro-4H-[1,3]dioxolo[4,5-c]pyrrole; (3aR,4R,6aS)-4-(tert-butyl-dimethyl-silanyloxymethyl)-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-C]pyrrole; (3aR,4R,6aS)-4-[[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]tetrahydro-2,2-dimethyl-4H-1,3-dioxolo[4,5-c]pyrrole. CAS No. 153172-31-7. Molecular formula: C14H29NO3Si. Mole weight: 287.47.
5-O-(tert-Butyldimethylsilyl)-2,3-O-isopropylidene-D-lyxofuranose. The mere mention of its name screams biochemical complexity and relevance. This alluring intermediate is a quintessential precursor in the synthesis of several biomolecules, including drugs, chiral inhibitors, and other biologically active agents. Its unrivaled usefulness in the biomedicine industry as a starting point for pharmaceutical intermediates has earned it a golden spot in the fight against a plethora of life-threatening diseases, from cancer to viral infections, to inflammation. Synonyms: (3aS,6R,6aS)-6-(((tert-butyldimethylsilyl)oxy)methyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-ol; 2-O,3-O-Isopropylidene-5-O-(tert-butyldimethylsilyl)-D-lyxofuranose; 5-O-[Dimethyl(2-methyl-2-propanyl)silyl]-2,3-O-isopropylidene-D-lyxofuranose; D-Lyxofuranose, 5-O-[(1,1-dimethylethyl)dimethylsilyl]-2,3-O-(1-methylethylidene)-. Grade: ≥95%. Molecular formula: C14H28O5Si. Mole weight: 304.45.
5-O-tert-Butyldimethylsilyl-2,3-O-isopropylidene-D-ribofuranose, an indispensible constituent within biomedicine, exhibits exceptional significance due to its distinctive chemical composition. Profoundly influencing the synthesis of numerous pharmaceutical agents, especially antiviral nucleoside analogs, this compound assumes a pivotal role. In addition to its role in drug development for combating HIV, herpes, and hepatitis, its unparalleled versatility renders it an essential foundation in the realm of biomedical research. Synonyms: 5-O-[(1,1-Dimethylethyl)dimethylsilyl]-2,3-O-(1-methylethylidene)-D-ribose; 2-O,3-O-Isopropylidene-5-O-(tert-butyldimethylsilyl)-beta-D-ribofuranose; 5-O-[Dimethyl(2-methyl-2-propanyl)silyl]-2,3-O-isopropylidene-β-D-ribofuranose; β-D-Ribofuranose, 5-O-[(1,1-dimethylethyl)dimethylsilyl]-2,3-O-(1-methylethylidene)-. Grade: ≥95%. CAS No. 68703-51-5. Molecular formula: C14H28O5Si. Mole weight: 304.45.
5-O-(tert-Butyldimethylsilyl)-2,3-O-isopropylidene-L-lyxofuranose, a fascinating carbohydrate derivative with a labyrinthine molecular structure, is a crucial intermediate utilized in diverse biochemical pathways. It is famed for its targeted drug delivery and is a potent agent in the synthesis of numerous drugs and compounds. Insulin resistance, cancer, viral infections, and more may be treated with this ambrosial substance. Synonyms: (3aR,6S,6aR)-6-(((tert-butyldimethylsilyl)oxy)methyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-ol; 5-O-[Dimethyl(2-methyl-2-propanyl)silyl]-2,3-O-isopropylidene-L-lyxofuranose; L-Lyxofuranose, 5-O-[(1,1-dimethylethyl)dimethylsilyl]-2,3-O-(1-methylethylidene)-. Grade: 95%. CAS No. 1266546-81-9. Molecular formula: C14H28O5Si. Mole weight: 304.45.
5-O-(tert-Butyldimethylsilyl)-2,3-O-isopropylidene-L-ribofuranose, a crucial intermediate in the creation of antiviral and antitumor medicines, exhibits broad-spectrum antiviral activity against an assortment of viruses. Used in HIV, herpes simplex virus, and select cancer treatments, it additionally plays a vital role in the creation of nucleoside analogs used to treat viral infections and cancer. Its scientific significance and multifaceted uses make it an indispensable tool in modern medicine. Synonyms: (3aS,6S,6aS)-6-[[tert-butyl(dimethyl)silyl]oxymethyl]-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-ol; 2-O,3-O-Isopropylidene-5-O-(tert-butyldimethylsilyl)-L-ribofuranose; 5-O-[Dimethyl(2-methyl-2-propanyl)silyl]-2,3-O-isopropylidene-L-ribofuranose; L-Ribofuranose, 5-O-[(1,1-dimethylethyl)dimethylsilyl]-2,3-O-(1-methylethylidene)-. Molecular formula: C14H28O5Si. Mole weight: 304.45.
6-O-α-Sialyl-2-acetamido-2-Deoxy-d-galactopyranoside. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CTK8F7186, 72506-87-7, AG-L-64328, 6-O-alpha-Sialyl-2-acetamido-2-deoxy-D-galactopyranoside. Product Category: Heterocyclic Organic Compound. CAS No. 72506-87-7. Molecular formula: C19H32N2O14. Mole weight: 512.46. Purity: 0.96. IUPACName: 5-acetamido-2-[(5-acetamido-3,4,6-trihydroxyoxan-2-yl)methoxy]-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid. Canonical SMILES: CC(=O)NC1C(CC(OC1C(C(CO)O)O)(C(=O)O)OCC2C(C(C(C(O2)O)NC(=O)C)O)O)O. Product ID: ACM72506877. Alfa Chemistry ISO 9001:2015 Certified.
7-O-(Triethylsilyl)-2'-O-tert-butyl(dimethyl)silyl-2-debenzoyl-[2,4]oxol Paclitaxel is an intermediate in the synthesis of Paclitaxel, which is a chemotherapy medication used to treat a number of types of cancer. Synonyms: Benzenepropanoic acid, β-(benzoylamino)-α-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, (2aS,3R,5S,5aS,7R,10S,12S,12aS,12bR)-2a,7-bis(acetyloxy)-2a,3,4,5,5a,6,7,10,11,12,12a,12b-dodecahydro-3,12-dihydroxy-5a,9,13,13-tetramethyl-6-oxo-5-[(triethylsilyl)oxy]-8,12-methano-2H-cyclodec[cd]isobenzofuran-10-yl ester, (αR,βS)-; (2α,5β,7β,10β,13α)-4,10-Diacetoxy-1,5-dihydroxy-9-oxo-7-[(triethylsilyl)oxy]-2,20-epoxytax-11-en-13-yl (2R,3S)-3-(benzoylamino)-2-{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-3-phenylpropanoate. Molecular formula: C52H75NO13Si2. Mole weight: 978.32.
7-O-(Triethylsilyl)-2'-O-tert-butyl(dimethyl)silyl-2-debenzoyl Paclitaxel is a derivative of Paclitaxel, which is a chemotherapy medication used to treat a number of types of cancer. Synonyms: (αR,βS)-β-(Benzoylamino)-α-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11,12-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-[(triethylsilyl)oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester; 2'-(Tert-butyldimethylsilyl)-2-debenzoyl-7-(triethylsilyl)paclitaxel; (2α,5β,7β,10β,13α)-4,10-Diacetoxy-1,2-dihydroxy-9-oxo-7-[(triethylsilyl)oxy]-5,20-epoxytax-11-en-13-yl (2R,3S)-3-(benzoylamino)-2-{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-3-phenylpropanoate. Grade: ≥95%. CAS No. 162459-94-1. Molecular formula: C52H75NO13Si2. Mole weight: 978.32.
9,9-Dioctyl-9H-9-silafluorene-2,7-bis(boronic acid pinacol ester). Uses: This material is used in the synthesis of low-band gap photovoltaic polymer materials that give power conversion efficiences of approx 3%. Group: Synthetic tools and reagents. Alternative Names: 9,9-Dioctyl-2,7-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9H-9-silafluorene, 5,5-Dioctyl-3,7-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5H-dibenzo[b,d]silole. CAS No. 958293-23-7. Pack Sizes: Packaging 500 mg in glass insert. Product ID: 2-[5,5-dioctyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[b][1]benzosilol-7-yl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane. Molecular formula: 658.64. Mole weight: C40H64B2O4Si. CCCCCCCC[Si]1 (CCCCCCCC)c2cc (ccc2-c3ccc (cc13)B4OC (C) (C)C (C) (C)O4)B5OC (C) (C)C (C) (C)O5. 1S / C40H64B2O4Si / c1-11-13-15-17-19-21-27-47 (28-22-20-18-16-14-12-2) 35-29-31 (41-43-37 (3, 4) 38 (5, 6) 44-41) 23-25-33 (35) 34-26-24-32 (30-36 (34) 47) 42-45-39 (7, 8) 40 (9, 10) 46-42 / h23-26, 29-30H, 11-22, 27-28H2, 1-10H3. QLOFNQWFMMGWBX-UHFFFAOYSA-N. ≥ 97%.
Albothricin
It is produced by the strain of SIPl-2985. It has anti-gram positive bacteria and negative bacteria activity, but has no effect on enterococcus faecalis and pseudomonas aeruginosa. Synonyms: [5-(3,6-diaminohexanoylamino)-3-hydroxy-2-(hydroxymethyl)-6-[(5-methyl-4-oxo-3a,6,7,7a-tetrahydro-1H-imidazo[4,5-c]pyridin-2-yl)amino]oxan-4-yl] carbamate; 4H-Imidazo(4,5-c)pyridin-4-one, 2-((4-O-(aminocarbonyl)-2-deoxy-2-((3,6-diamino-1-oxohexyl)amino)-beta-D-gulopyranosyl)amino)-1,3a,5,6,7,7a-hexahydro-5-methyl-, (3aS-(2(R*),3aalpha,7abeta))-. Grade: 95%. CAS No. 103867-06-7. Molecular formula: C20H36N8O7. Mole weight: 500.55.
Intermediate in the synthesis of Acylfulvene derivative antitumor agents. Group: Biochemicals. Alternative Names: α - [1- [ [ (1, 1-Di methyl ethyl) di methyl silyl] oxy] -3- (tri methyl silyl) -2-propynyl] - α '-ethynyl- α , α '-di methyl -1, 1-cyclopropane dimethanol. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
α-2,3/8-sialyltransferase from Campylobacter jejuni, Recombinant
Sialyltransferases are enzymes that transfer sialic acid to nascent oligosaccharide. Each sialyltransferase is specific for a particular sugar substrate. Sialyltransferases add sialic acid to the terminal portions of the sialylated glycolipids (gangliosides) or to the N-or O-linked sugar chains of glycoproteins. Sialyltransferases belong to glycosyltransferase family 29 (CAZY GT_29) which use a nucleotide monophosphosugar as the donor (CMP-NeuA) instead of a nucleotide diphosphosugar. Group: Enzymes. Synonyms: α (2,3)-Sialyltransferase; Beta-galactoside alpha-2,3-sialyltransferase; Beta-galactosamide alpha-2,3-sialyltransferase; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase. Enzyme Commission Number: EC 2.4.99.-. Purity: min 95% by SDS-PAGE. α-Sialyltransferase. Mole weight: 31 kDa. Source: E. coli. Species: Campylobacter jejuni. α (2,3)-Sialyltransferase; Beta-galactoside alpha-2,3-sialyltransferase; Beta-galactosamide alpha-2,3-sialyltransferase; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase; α-2,3/8-sialyltransferase; EC 2.4.99.-. Cat No: NATE-1476.
BD1063 dihydrochloride
BD1063 dihydrochloride is a potent and selective antagonist of sigma 1 receptor (Ki = 9.15 nM) with 50-fold more selective over sigma-2 (Ki = 449 nM) and >100-fold more selective over 9 other tested neurotransmitter receptors. Synonyms: BD1063 dihydrochloride; BD-1063 dihydrochloride; 1-(3,4-dichlorophenethyl)-4-methylpiperazine dihydrochloride; Piperazine, 1-[2-(3,4-dichlorophenyl)ethyl]-4-methyl-, dihydrochloride. Grade: ≥98%. CAS No. 206996-13-6. Molecular formula: C13H20Cl4N2. Mole weight: 346.12.
CM398 has preferential affinity for sigma-2 receptor compared with sigma-1 receptor and at least four other neurotransmitter receptors sites, including the norepinephrine transporter. Synonyms: 1-(4-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1h)-yl)butyl)-3-methyl-1h-benzo[d]imidazol-2(3h)-one. Grade: 98%. CAS No. 1121931-70-1. Molecular formula: C23H29N3O3. Mole weight: 395.49.
CM398
CM398 is a highly selective, orally active sigma-2 receptor ligand ( K i =0.43 nM), with high sigma-1/sigma-2 selectivity rato (1000-fold). CM398 shows notable affinity for dopamine (K i =32.90 nM) and serotonin transporters (K i =244.2 nM). CM398 shows promising anti-inflammatory analgesic effects in the formalin model of inflammatory pain in mice [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1121931-70-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145628.
CT1812
CT1812 (Sigma-2 receptor antagonist 1) is an orally active and brain penetrant sigma-2 receptor antagonist with a K i of 8.5 nM. CT1812 can be used for the research of Alzheimers disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Sigma-2 receptor antagonist 1. CAS No. 1802632-22-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-111669.
CYR-101
MIN-101, a novel cyclic amide derivative, is a 5-HT2A and sigma 2 receptor antagonist (Ki = 7.53 nM for 5-HT2A and 8.19 nM for sigma-2, respectively). Synonyms: 2-((1-(2-(4-fluorophenyl)-2-oxoethyl)piperidin-4-yl)methyl)isoindolin-1-one; CYR-101; UNII-4P31I0M3BF; MT-210; MIN101; CYR101; MT210; MIN 101; CYR 101; MT 210. CAS No. 359625-79-9. Molecular formula: C22H23FN2O2. Mole weight: 366.43.
D-Glucitol-2-13C
D-Glucitol-2-13C. Group: Biochemicals. Alternative Names: D-Sorbitol-2-13C; Glucarine-2-13C; Esasorb-2-13C; Cholaxine-2-13C; Karion-2-13C; Sionite-2-13C; Sionon-2-13C. Grades: Highly Purified. CAS No. 287100-73-6. Pack Sizes: 25mg. Molecular Formula: C513CH14O6, Molecular Weight: 183.17. US Biological Life Sciences.
Worldwide
D-Glucitol-2-d
D-Glucitol-2-d. Group: Biochemicals. Alternative Names: D-Sorbitol-2-d; Glucarine-2-d; Esasorb-2-d; Cholaxine-2-d; Karion-2-d; Sionite-2-d; Sionon-2-d. Grades: Highly Purified. CAS No. 75607-68-0. Pack Sizes: 25mg. Molecular Formula: C6H13DO6, Molecular Weight: 183.18. US Biological Life Sciences.
Worldwide
D-Sorbitol-[2-13C]
D-Sorbitol-2-[13C] is the labelled analogue of D-Sorbitol, which is a sugar alcohol that is used as a sweetener or humectant. Synonyms: D-Glucitol-2-13C; D-Sorbitol-2-13C; Glucarine-2-13C; Esasorb-2-13C; Cholaxine-2-13C; Karion-2-13C; Sionite-2-13C; Sionon-2-13C. Grade: 99% (CP); 99% atom 13C. CAS No. 287100-73-6. Molecular formula: C5[13C]H14O6. Mole weight: 183.16.
endo-α-sialidase
Although the name endo-N-acetylneuraminidase has also been used for this enzyme, this is misleading since its activity is not restricted to acetylated substrates. An exo-α-sialidase activity is listed as EC 3.2.1.18 exo-α-sialidase. See also EC 4.2.2.15 anhydrosialidase. Group: Enzymes. Synonyms: endo-N-acylneuraminidase; endoneuraminidase; endo-N-acetylneuraminidase; poly(α-2,8-sialosyl) endo-N-acetylneuraminidase; poly(α-2,8-sialoside) α-2,8-sialosylhydrolase; endosialidase; endo-N. Enzyme Commission Number: EC 3.2.1.129. CAS No. 91195-87-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3812; endo-α-sialidase; EC 3.2.1.129; 91195-87-8; endo-N-acylneuraminidase; endoneuraminidase; endo-N-acetylneuraminidase; poly(α-2,8-sialosyl) endo-N-acetylneuraminidase; poly(α-2,8-sialoside) α-2,8-sialosylhydrolase; endosialidase; endo-N. Cat No: EXWM-3812.
Glycerol phenylbutyrate
Glycerol phenylbutyrate is a generation ammonia scavenger drug that is currently under development for treatment of urea cyclic disorders, which is a sigma-2 (σ2) receptor ligand. Uses: Glycerol phenylbutyrate is used for treatment of certain inborn urea cycle disorders. Synonyms: HPN-100; 2,3-Bis(4-phenylbutanoyloxy)propyl 4-phenylbutanoate; Ravicti; GPB. Grade: 98%. CAS No. 611168-24-2. Molecular formula: C33H38O6. Mole weight: 530.65.
Glycerol phenylbutyrate
Glycerol phenylbutyrate is a sigma-2 (σ2) receptor ligand, with a pK i of 8.02. Glycerol phenylbutyrate (GPB) is a new generation ammonia scavenger agent [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HPN-100. CAS No. 611168-24-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B2087.
N-[4-Chloro-3-(Triisopropylsilyloxy)Phenyl]-2,2-Dimethylpropanamide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-[4-Chloro-3-[[Tris(1-Methylethyl)Silyl]Oxy]Phenyl]-2,2-Dimethylpropanamide. Product Category: Heterocyclic Organic Compound. Appearance: White Solid. CAS No. 342621-20-9. Molecular formula: C20H34ClNO2Si. Mole weight: 384.03 g/mol. Purity: 0.96. IUPACName: N-[4-chloro-3-tri(propan-2-yl)silyloxyphenyl]-2,2-dimethylpropanamide. Canonical SMILES: CC(C)[Si](C(C)C)(C(C)C)OC1=C(C=CC(=C1)NC(=O)C(C)(C)C)Cl. Density: 1.019g/cm³. Product ID: ACM342621209. Alfa Chemistry ISO 9001:2015 Certified.
NAD-dependent protein deacetylase sirtuin-2 (192-200)
NAD-dependent protein deacetylase sirtuin-2 (192-200) is amino acids 192 to 200 fragment of NAD-dependent protein deacetylase sirtuin-2. NAD-dependent protein deacetylase sirtuin-2 plays a major role in the control of cell cycle progression and genomic stability. Synonyms: Regulatory protein SIR2 homolog 2 (192-200); SIR2-like protein 2 (192-200).
Poly[2,7-(9,9-bis(2-ethylhexyl)-dibenzosilole)-alt-4,7-bis(thiophen-2-yl)benzo-2,1,3-thiadiazole]. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Poly[2,7-(9,9-bis(2-ethylhexyl)-dibenzosilole)-alt-4,7-bis(thiophen-2-yl)benzo-2,1,3-thiadiazole];Poly[2,1,3-benzothiadiazole-4,7-diyl-2,5-thiophenediyl(9,9-dioctyl-9H-9-silafluorene-2,7-diyl)-2,5-thiophenediyl];Poly[2,7-(9,9-dioctyl-dibenzosilole)-alt-4. Product Category: Organic & Printed Electronics. CAS No. 1004272-92-7. Product ID: ACM1004272927. Alfa Chemistry ISO 9001:2015 Certified.
PSiF-DBT
PSiF-DBT is a conductive polymer that can be used as an active layer with thermal stability and high degree of π-electron delocalization. It has a high mobility of charge carrier around 1×10-3cm2 /(V s) which can be useful in organic electronics. Uses: Psif-dbt can be used as a semiconducting polymer for the fabrication of polymeric solar cells (pscs) and organic photovoltaic cells (opvs). Group: Organic field effect transistor (ofet) materials organic solar cell (opv) materials. Alternative Names: Poly[2,7-(9,9-dioctyl-dibenzosilole)-alt-4,7-bis(thiophen-2-yl)benzo-2,1,3-thiadiazole], Poly[2,1,3-benzothiadiazole-4,7-diyl-2,5-thiophenediyl(9,9-dioctyl-9H-9-silafluorene-2,7-diyl)-2,5-thiophenediyl]. CAS No. 1004272-92-7. Pack Sizes: 100 mg in glass insert. Molecular formula: average Mn 10000-80000. Mole weight: (C42H46N2S3Si)n.
Roluperidone
Roluperidone (CYR-101) is a novel cyclic amide derivative that has high equipotent affinities for 5-HT 2A and sigma-2 receptors ( K i of 7.53 nM and 8.19 nM for 5-HT 2A and sigma-2, respectively). Uses: Scientific research. Group: Signaling pathways. Alternative Names: CYR-101; MIN-101; MT-210. CAS No. 359625-79-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19469.
Signiferin-2.1
Signiferin-2.1 is an antibacterial peptide isolated from Crinia signifera. It has activity against gram-negative bacteria. Synonyms: Ile-Ile-Gly-His-Leu-Ile-Lys-Thr-Ala-Leu-Gly-Met-Leu-Gly-Leu. Grade: >96%. Molecular formula: C72H129N19O16S. Mole weight: 1549.00.
Siramesine (Lu 28-179) hydrochloride is a potent sigma-2 receptor agonist. Siramesine hydrochloride has a subnanomolar affinity for sigma-2 receptors (IC50=0.12 nM) and exhibits a 140-fold selectivity for sigma-2 receptors over sigma-1 receptors (IC50=17 nM). Siramesine hydrochloride triggers cell death through destabilisation of mitochondria, but not lysosomes. Anti-cancer activity[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lu 28-179 hydrochloride. CAS No. 224177-60-0. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14221A.