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| Product | Description | |
|---|---|---|
| SKI II | 2-(p-Hydroxyanilino)-4-(p-chlorophenyl)thiazole (SK1-II) is a cell permeable, potent, and specific inhibitor of sphingosine kinase (IC50 = 0.5 μM). The compound does not bind to the ATP-binding site and does not affect the kinase activities of hERK2, hPI3K, or hPKCα at concentrations up to 60 μM. SK1-II showed anti-tumor properties, inducing apoptosis in a number of cell lines including those that express Pgp or MRP1 drug-transport proteins. Synonyms: SphK-I2; SKI-II; SKI II. Sphingosine kinase inhibitor II. Grades: >98%. CAS No. 312636-16-1. Molecular formula: C15H11ClN2OS. Mole weight: 302.78. |  |
| SKI II | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. |  |
| SKI II | SKI II. Group: Biochemicals. Grades: Purified. CAS No. 312636-16-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| SKI II | SKI-II is an oral active and synthetic inhibitor of sphingosine kinase (SK) activity, with IC 50 values of 78 μM and 45 μM for SK1 and for SK2, respectively. SKI II causes an irreversible inhibition of SK1 by inducing its lysosomal and/or proteasomal degradation [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 312636-16-1. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13822. |  |
| SKI-II, Sphingosine Kinase Inhibitor (4- [ [4- (4-Chlorophenyl) -2-thiazolyl] amino] phenol) | Cell-permeable. SKI-II is selective a non-lipid sphingosine kinase (SK) inhibitor. It displays non-ATP-competitive inhibition of human recombinant GST-SK 1 with an IC50 value of 0.5uM, with no inhibition against ERK2, PI3-kinase, or PKCa at concentrations up to 60uM. Group: Biochemicals. Grades: Highly Purified. CAS No. 312636-16-1. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| Tin(II) Chloride [for Perovskite precursor] | Stannous chloride, solid appears as crystalline mass or flaky solid with a fatty appearance. Density 3.95 g / cm³. Melting point 247°C. Burns, but may be difficult to ignite. Toxic by ingestion. Irritates skin and eyes. Used in the manufacture of dyes, pharmaceuticals and as a tanning agent.;DryPowder; OtherSolid, Liquid; PelletsLargeCrystals;COLOURLESS OR WHITE CRYSTALS. Group: Perovskite solar cell (psc) materials. CAS No. 7772-99-8. Product ID: dichlorotin. Molecular formula: 189.61g/mol. Mole weight: SnCl2;SnCl2;Cl2Sn. Cl[Sn]Cl. InChI=1S/2ClH.Sn/h2*1H;/q;;+2/p-2. AXZWODMDQAVCJE-UHFFFAOYSA-L. |  |
| 1-(4-Hydroxyphenyl)thiourea | 1-(4-Hydroxyphenyl)thiourea is an intermediate in the synthesis of (SKI II), a nonlipid inhibitor of sphingosine kinase. SKI II s orally bioavailable and has shown significant inhibition of tumor growth in mice. Group: Biochemicals. Grades: Highly Purified. CAS No. 1520-27-0. Pack Sizes: 1g, 5g. Molecular Formula: C7H8N2OS, Molecular Weight: 168.22. US Biological Life Sciences. | Worldwide |
| 15-Lipoxygenase-2 from human, Recombinant | Two types of 15-lipoxygenase (15-LO) have been discovered and characterized, both of which metabolize arachidonic acid (AA) to produce 15(S)-hydroxyeicosatetraenoic acid (15(S)-HETE). 15-LO-1 oxygenates AA at both C-15 and C-12, whereas 15-LO-2 exclusively oxygenates C-15 of AA. Human 15-LO-2 has a molecular mass of approximately 76 kDa and exhibits approximately 40% identity to the reticulocyte 15-LO-1. Expression of 15-LO-2 appears to be restricted to prostate, lung, skin, and cornea and may play a role in the normal development of these tissues. The protein levels and enzymatic activity of 15-LO-2 are both down-regulated in prostate cancer compared with normal and benign prostate tissues, implicating a possible protective role for 15-LO-2 against tumor formation. Group: Enzymes. Synonyms: Arachidonate 15-lipoxygenase type II; 15-lipoxygenase-2; 15-LO-2; 15-LOX-2; ALOX15B. Enzyme Commission Number: EC 1.13.11.33. Purity: > 95% estimated by SDS-PAGE. Lipoxygenase. Mole weight: 76 kDa. Activity: 234.15 U/ml. Stability: As supplied, 6 months from the QC date provided on the Certificate of Analysis, when stored properly. Storage: at -80°C. Form: PBS, pH 7.4, 1 mM DTT and 20% glycerol. Source: E. coli. Species: Human. Arachidonate 15-lipoxygenase type II; 15-lipoxygenase-2; 15-LO-2; 15-LOX-2; ALOX15B. Cat No: NATE-1248. |  |
| Alalevonadifloxacin | Alalevonadifloxacin is a quinolone antibacterial. It is a DNA gyrase and DNA topoisomerase inhibitor. Alalevonadifloxacin is potentially useful to treat bacterial Gram-positive, Gram-negative and anaerobic infections. Phase II clinical trials for the treatment of Methicillin-resistant Staphylococcus aureus infections and Skin and soft tissue infections are on-going. Uses: Methicillin-resistant staphylococcus aureus infections; skin and soft tissue infections. Synonyms: WCK2349; WCK 2349; WCK-2349; (5S)-8-[4-(L-alanyloxy)piperidin-1-yl]-9-fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid. Grades: 98%. CAS No. 706809-20-3. Molecular formula: C22H26FN3O5. Mole weight: 431.46. | |
| asparaginase | Asparaginase, also known as crisantaspase, is an enzyme that is used as a medication and in food manufacturing. As a medication it is used to treat acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), and non-Hodgkin's lymphoma. It is given by injection into a vein, muscle, or under the skin. A pegylated version is also available. In food manufacturing it is used to decrease the acrylamide. Group: Enzymes. Synonyms: asparaginase II; L-asparaginase; colaspase; elspar; leunase; crasnitin; α-asparaginase. Enzyme Commission Number: EC 3.5.1.1. CAS No. 9015-68-3. Asparaginase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4377; asparaginase; EC 3.5.1.1; 9015-68-3; asparaginase II; L-asparaginase; colaspase; elspar; leunase; crasnitin; α-asparaginase. Cat No: EXWM-4377. | |
| C2 Ceramide | C2 Ceramide (Ceramide 2) is the main lipid of the stratum corneum and a protein phosphatase 1 (PP1) activator. C2 Ceramide activates PP2A and ceramide-activated protein phosphatase (CAPP). C2 Ceramide induces cells differentiation, autophagy and apoptosis , inhibits mitochondrial respiratory chain complex III. C2 Ceramide is also a skin conditioning agent that protects the epidermal barrier from water loss [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ceramide 2. CAS No. 3102-57-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-101180. | |
| Candesartan Cilexetil | Candesartan Cilexetil (TCV-116) is an angiotensin II receptor inhibitor. Candesartan Cilexetil ameliorates the pulmonary fibrosis and has antiviral and skin wound healing effect. Candesartan Cilexetil can be used for the research of high blood pressure [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TCV-116. CAS No. 145040-37-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-17505. | |
| Chymase from Human, Recombinant | Chymases are a family of serine proteases found primarily in mast cells, though also present in basophil granulocytes (e.g. alpha chymase mcpt8). They show broad peptidolytic activity and are involved in a variety of functions. For example, chymases are released by mucosal mast cells upon challenge with parasites and parasite antigens promoting an inflammatory response. Chymases are also known to convert angiotensin I to angiotensin II and thus play a role in hypertension and atherosclerosis. Because of its role in inflammation it has been investigated as a target in the treatment of asthma. Applications: Chymase has been implicated in generation of angiotensin ii and cleavag... Synonyms: mast cell protease I; skeletal muscle protease; skin chymotryptic proteinase; mast cell serine proteinase, chymase; skeletal muscle (SK) protease; chymase; EC 3.4.21.39; 97501-92-3. Enzyme Commission Number: EC 3.4.21.39. CAS No. 97501-92-3. Purity: >90% (SDS-PAGE). CMA1. Mole weight: ~30 kDa. Activity: >40 units/mg protein. Storage: Store at -20°C. Form: Supplied as a solution in 20 mM Tris, 0.8 M NaCl and 25% glycerol, pH 7.6. Source: Pichia pastoris. Species: Human. mast cell protease I; skeletal muscle protease; skin chymotryptic proteinase; mast cell serine proteinase, chymase; skeletal muscle (SK) protease; chymase; EC 3.4.21.39; 97501-92-3. Cat No: NATE-0817. | |
| Collagens polypeptide | Collagen is a major structural protein that provides structure and strength to tissues in the body. Due to its biocompatibility, biodegradability, and high abundance, collagen has been utilized for many applications in biomedical research. Applications of fibrillar collagen may include: Development of collagen-based tissues for skin replacement, bone substitutes and to generate artificial blood vessels and valves. Drug delivery systems such as sponges for burns/wounds, formulations with liposomes for sustained drug delivery, materials for transdermal drug delivery, and nanoparticles for gene delivery. As collagen scaffolds for research in cancer, electrophysiological protocols, neuron myelination, immunology and other cell culture applications. Synonyms: Collagenpowder; collagens; BOVINE COLLAGEN TYPE II; COLLAGEN TYPE IV, HUMAN; COLLAGEN, TYPE IV, HUMAN PLACENTA; COLLAGEN TYPE IV (HU PLACENTA); COLLAGEN TYPE V (HU PLACENTA); COLLAGEN, TYPE 5. CAS No. 9007-34-5. | |
| Coproporphyrin III dihydrochloride | Coproporphyrin III dihydrochloride is a bioactive molecule excreted by nostril- and skin-associated Propionibacterium species that induces aggregation of Staphylococcus aureus (conditions: during early stationary phase growth, low pH: 4-6). Coproporphyrin III dihydrochloride also induces plasma-independent biofilm formation on abiotic surfaces by Staphylococcus aureus. Coproporphyrin III dihydrochloride may be an important mediator of S. aureus accumulation and/or biofilm formation in the nostrils or other sites where Propionibacterium and S. aureus inhabit [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Zincphyrin dihydrochloride. CAS No. 68938-73-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-W412175. | |
| Edasalonexent | Edasalonexent, also known as CAT-1004, is a NF-kappa B inhibitor under the development of Catabasis Pharmaceuticals and Sarepta Therapeutics. It is a Inflammation mediator inhibitor and could be an anti-inflammatory drug candidate. In Apr 2016, Phase-II clinical trials in Duchenne muscular dystrophy (In children) in USA were on-going. In Sep 2016, Catabasis Pharmaceuticals and Sarepta Therapeutics agreed to co-develop edasalonexent with an exon skipping treatment together in USA for Duchenne muscular dystrophy. Uses: Anti-inflammatory; duchenne muscular dystrophy. Synonyms: CAT-1004; CAT1004; CAT 1004; Edasalonexent; Sodium salicylate-docosahexaenoic acid conjugate;N-(2-((4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenamido)ethyl)-2-hydroxybenzamide. Grades: 98%. CAS No. 1204317-86-1. Molecular formula: C31H42N2O3. Mole weight: 490.69. | |
| Eptaplatin | A coordination compound for treatment of cervix cancer. Group: Biochemicals. Alternative Names: (SP-4-2)-[(4R, 5R)-2-(1-Methylethyl-1, 3-dioxolane4, 5-dimethanamine-kN4, kN5][propanedioato(2-)-kO1, kO3]platinum; Heptaplatin; cis-[ (4R, 5R)-4, 5-bis (aminomethyl)-2-isopropyl-1, 3-dioxolane] (malonate)platinum (II); SKI 2053R. Grades: Highly Purified. CAS No. 146665-77-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Fluocinolone acetonide | Fluocinolone acetonide is a corticosteroid primarily used in dermatology to reduce skin inflammation and relieve itching. It was also found to strongly potentiate TGF-β-associated chondrogenesis of bone marrow mesenchymal stem/progenitor cells, by increasing the levels of collagen type II by more than 100 fold compared to the widely used dexamethasone. Uses: Glucocorticoids, synthetic; glucocorticoids, topical. Synonyms: Isepamicine (Isepamycin, sch21420) Sulphate. Grades: >98%. CAS No. 67-73-2. Molecular formula: C24H30F2O6. Mole weight: 452.488. | |
| Gepotidacin | Gepotidacin is a potent Type II DNA topoisomerase inhibitor. It is a novel antibacterial drug candidate. It is used for the treatment of gram positive bacterial infection of skin and skin structure. It is also used for the treatment of gonorrhea. It was developed by GlaxoSmithKline R & D and in clinic phase 2 trials. Uses: Gepotidacin is used for the treatment of gram positive bacterial infection of skin and skin structure. it is also used for the treatment of gonorrhea. Synonyms: GSK-2140944; GSK2140944; GSK 2140944; GSK-2140944E; GSK2140944E; GSK 2140944E; Gepotidacin;(2R)-2-[(4-{[(3,4-dihydro-2H-pyrano[2,3-c]pyridin- 6-yl)methyl]amino}piperidin-1-yl)methyl]-1,2-dihydro- 3H,8H-2a,5,8a-triazaacenaphthylene-3,8-dione. Grades: >98%. CAS No. 1075236-89-3. Molecular formula: C24H28N6O3. Mole weight: 448.53. | |
| Gluconic acid copper(II) salt, 98% | Gluconic acid copper(II) salt, 98%. Uses: Copper gluconate is cited as having skin-conditioning and skinprotecting functions. Group: Electrolytes. Alternative Names: Chelates of copper gluconate; KS-00000WNP; DB11246; D-Gluconicacidcopper(II)salt; HSDB 261; Copper gluconate (USP); Copper gluconate [USP]; Copper(II) (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate; AN-45570; SCHEMBL23076. CAS No. 527-09-3. Product ID: copper; (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate. Molecular formula: 453.84g/mol. Mole weight: C12H22CuO14. C(C(C(C(C(C(=O)[O-])O)O)O)O)O. C(C(C(C(C(C(=O)[O-])O)O)O)O)O. [Cu+2]. InChI=1S/2C6H12O7. Cu/c2*7-1-2(8)3(9)4(10)5(11)6(12)13; /h2*2-5, 7-11H, 1H2, (H, 12, 13); /q; ; +2/p-2/t2*2-, 3-, 4+, 5-; /m11. /s1. OCUCCJIRFHNWBP-IYEMJOQQSA-L. | |
| Glucose oxidase | Glucose oxidase. Synonyms: notatin;oxidaseglucose;1.1.3.4;BETA-D-GLUCOSE: OXYGEN 1-OXIDOREDUCTASE;BETA-D-GLUCOSE: OXYGEN 1-OXIDOREDUCTASE TYPE II;BETA-D-GLUCOSE: OXYGEN 1-OXIDOREDUCTASE TYPE II-S;BETA-D-GLUCOSE: OXYGEN 1-OXIDOREDUCTASE TYPE VII;BETA-D-GLUCOSE: OXYGEN 1-OXIDOREDUCTASE TYPE X-S. CAS No. 9001-37-0. Pack Sizes: 1 kg. Product ID: CDF4-0031. Category: Enzyme Preparations. Product Keywords: Food Ingredients; Enzyme Preparations; Enzyme Preparations; Glucose oxidase; CDF4-0031; 9001-37-0; 232-601-0; 9001-37-0. Purity: 0.99. Color: Yellow. EC Number: 232-601-0. Physical State: Solution (clear). Storage: -20°C. Application: glucose oxidase is an enzyme used to help stabilize a formulation. It can also improve skin feel and condition. Density: 1.00 g/mL at 20 °C. Product Description: Produced by the controlled fermentation of Aspergillus niger var. as a yellow to brown solution or as a yellow to tan or off-white powder. Soluble in water, the solutions being light yellow to brown, but practically insoluble in alcohol, chloroform or ether. |  |
| Melanotan II (MT-II, MSHa) | Melanotan and Melanotan-II are both analogs of the peptide hormone alpha melanocyte stimulating hormone ( -MSH) that tend to induce skin tanning. Unlike Melanotan, Melanotan-II has the additional effect of increasing libido. Melanotan II has aphrodisiac properties. Molecular weight of 1024.2 dalton. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 20mg, 100mg. US Biological Life Sciences. | Worldwide |
| MitMAB | MitMAB, an organic building block and cationic surfactant, is a dynamin inhibitor that inhibits the GTPase activity of dynamin I (Ki = 940 nM; IC50=3.1 μM). It has been used in a study to assess a surfactant-controlled synthetic method to obtain a nanophase of mesoporous ceria-zirconia solid solution containing cationic defects in the crystalline structure. Uses: Quaternary ammonium compounds are used in disinfectants and sanitizers to treat swimming pools and industrial water reservoirs, as antiseptics for cleaning wounds, skin, and burns, in hair conditioners, as softeners for textiles and paper, and as pigment dispersers. Synonyms: Tetradecyltrimethylammonium bromide; (1-Tetradecyl)trimethylammonium Bromide Cetrimide BP; MTAB ; Microcide II; Morpan T; Myristyltrimethylammonium bromide; Myrtrimonium Bromide; Mytab; N,N,N-Trimethyl-1-tetradecanaminium Bromide;N-Tetradecyl-N,N,N-trimethylammonium Bromide; Pentonium 4Br40;Quaternium 13; Querton 14Br40; TTAB; TTAB (surfactant); Tetradecyltrimethylammonium Bromide; Tetradonium Bromide; Trimethylmyristylammonium Bromide; n-Tetradecyltrimethylammonium Bromide. Grades: >98.0%(T). CAS No. 1119-97-7. Molecular formula: C17H38BrN. Mole weight: 336.39. | |
| MK0873 | MK0873 is a phosphodiesterase 4 (PDE4) inhibitor. It has shown as an innovative tool to design topical formulation to achieve desired pharmacokinetics in humans along with a minipig skin biopsy model. It was developed by Merck. It was used to treat rheumatoid arthritis in phase II clinical trials and plaque psoriasis in phase I clinical trials, but it has no recent research progress. Uses: Mk0873 was used to treat rheumatoid arthritis and plaque psoriasis. Synonyms: N-cyclopropyl-1-[3-[2-(1-oxidopyridin-1-ium-3-yl)ethynyl]phenyl]-4-oxo-1,8-naphthyridine-3-carboxamide;MK0873; MK 0873; MK-0873;3-((3-(3-(cyclopropylcarbamoyl)-4-oxo-1,8-naphthyridin-1(4H)-yl)phenyl)ethynyl)pyridine 1-oxide. Grades: 98%. CAS No. 500355-52-2. Molecular formula: C25H18N4O3. Mole weight: 422.44. | |
| Nadifloxacin | Nadifloxacin is a potent, broad-spectrum, quinolone agent approved for topical use in acne vulgaris and skin infections. Uses: Topoisomerase ii inhibitors. Synonyms: Nadifloxacine; Nadixa; OPC-7251; OPC7251; OPC 7251. Grades: >98%. CAS No. 124858-35-1. Molecular formula: C19H21FN2O4. Mole weight: 360.38. | |
| Native Human Tryptase | Tryptase is a member of the serine protease S1 family. It is the predominant neutral protease of the mast cell granules. Within the mast cell granule it exists as a heparin-stabilized active tetramer. Stabilization is a result of the high negative charge density of the glycosaminoglycan. This stabilization activity is observed with heparins with a MW > 6 kDa as well as other glycosaminoglycans such as dextran sulfate or chondroitin sulfates. Removal of heparin results in dissociation of the tetramer and inactivation of the enzyme. High concentrations of NaCl will result in the dissociation of heparin. Tryptase is a glycoprotein released from mast cells during anaphylaxis, which pe...acterized recombinant rat mast cell protease 7 expressed in pichia pastoris. tryptase has also been used in a study to investigate drug allergies in mast cell disease. Group: Enzymes. Synonyms: tryptase; mast cell tryptase; mast cell protease II; skin tryptase; lung tryptase; pituitary tryptase; mast cell neutral proteinase; mast cell tryptase; mast cell neutral proteinase; mast cell serine proteinase II; mast cell proteinase II; mast cell serine proteinase tryptase; rat mast cell protease II; tryptase M; EC 3.4.21.59. Enzyme Commission Number: EC 3.4.21.59. CAS No. 97501-93-4. Tryptase. Mole weight: Molecular Weight: ~135 kDa (Human) (Non-covalently linked tetramer with two sets o | |
| Oncorhyncin III | Oncorhyncin III is an antimicrobial peptide comprising residues 1-66 of Non-histone chromosomal protein H6. It is isolated from Rainbow trout skin secretions, Oncorhynchus mykiss, and has antibacterial activity. Synonyms: Oncorhyncin 3. Grades: >98%. Mole weight: 6671.00. | |
| Phorbol 12-myristate 13-acetate (PMA, TPA, 12-O-Tetradecanoylphorbol 13-acetate) | Most commonly-used phorbol ester. Binds to and activates protein kinase C (PKC) at nM concentrations. Induces cell growth arrest through a variety of pathways including the mitogen-activated protein kinases (MAPKs), p38 and c-Jun N-terminal kinase (JNK) pathways mediated by cyclin dependent kinase (CDK) inhibitors such as p21WAF1/CIP1, p27KIP1, p15 and p16. Potent mouse skin tumor promoter. Promoter of inducible NOS (iNOS; NOS II). Apoptosis inducer. Potential effective cancer therapeutic agent. Inhibitor of anti-lipolytic activity of insulin. Group: Biochemicals. Alternative Names: PMA; TPA; 12-O-Tetradecanoylphorbol 13-acetate. Grades: Highly Purified. CAS No. 16561-29-8. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C36H56O8, Molecular Weight: 616.83. US Biological Life Sciences. | Worldwide |
| Phytosphingosine | Phytosphingosine is a phospholipid with anti-inflammatory, antibacterial, and anti-cancer activities, which can induce apoptosis. Phytosphingosine is an immune regulator and can be used in the study of inflammatory skin diseases. Phytosphingosine is also an activator of GPR120 with an IC 50 value of 33.4 μM and can be used in the study of type II diabetes [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: 4-Hydroxysphinganine. CAS No. 554-62-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W011303. | |
| Tenuazonic acid | Tenuazonic acid is a nonhost-selective mycotoxin belonging to the tetramic acids family. Tenuazonic acid inhibits protein biosynthesis on ribosomes by suppressing the release of new protein. Tenuazonic acid is acutely toxic, and oral LD 50 is set between 81-186 mg/kg in rats and mice. Tenuazonic acid blocks electron transport beyond the primary quinone receptor (QA) by interacting with the D1 protein and is a photosystem II (PSII) inhibitor. In addition, Tenuazonic acid has antiviral effects on measles virus, enterovirus, respiratory virus and so on. Tenuazonic acid has an inhibitory effect on skin cancer [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Natural products. CAS No. 610-88-8. Pack Sizes: 5 mg. Product ID: HY-N6715. | |
| tryptase | Occurs as a tetrameric molecule with high affinity for heparin, in mast cell granules. In peptidase family S1 (trypsin family). Not inhibited by α1-proteinase inhibitor or α2-macroglobulin. Group: Enzymes. Synonyms: mast cell tryptase; mast cell protease II; skin tryptase; lung tryptase; pituitary tryptase; mast cell neutral proteinase; mast cell tryptase; mast cell neutral proteinase; mast cell serine proteinase II; mast cell proteinase II; mast cell serine proteinase tryptase; rat mast cell protease II; tryptase M. Enzyme Commission Number: EC 3.4.21.59. CAS No. 97501-93-4. Tryptase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4149; tryptase; EC 3.4.21.59; 97501-93-4; mast cell tryptase; mast cell protease II; skin tryptase; lung tryptase; pituitary tryptase; mast cell neutral proteinase; mast cell tryptase; mast cell neutral proteinase; mast cell serine proteinase II; mast cell proteinase II; mast cell serine proteinase tryptase; rat mast cell protease II; tryptase M. Cat No: EXWM-4149. | |
| VX-148 | VX-148 is a novel, uncompetitive IMPDH inhibitor with a K(I) value of 6 nM against IMPDH type II enzyme. VX-148 is slightly more potent than mycophenolic acid and VX-497 in inhibiting the proliferation of mitogen-stimulated primary human lymphocytes (IC(50) value of ~80 nM). VX-148 does not inhibit proliferation of nonlymphoid cell types such as fibroblasts, indicating selectivity for inhibition of IMPDH activity. VX-148 significantly prolongs skin graft survival at 100 mg/kg b.i.d. in mice. Synonyms: VX148; VX 148; (R)-1-cyanobutan-2-yl ( (S) -1- (3- (3- (4-cyano-3-methoxyphenyl) ureido) phenyl) ethyl) carbamate. Grades: 98%. CAS No. 297730-05-3. Molecular formula: C23H25N5O4. Mole weight: 435.48. | |
| Collagen Type II, Human Sternal Cartilage, Dilution Buffer (10X) | Collagen is an inert, rigid protein found predominantly in skin, ligaments, bones and teeth. Its most distinctive attribute, essential to a transmitter of mechanical force, is inelasticity. Its fundamental structural unit is tropo-collagen, a molecular rod about 2600Å in length and 15Å in diameter and 300,000 molecular weight. In tendons these macromolecules, grouped as collagen fibrils, run parallel to the axis. In skin the fibrils are interlaced and branched. Group: Molecular Biology. Grades: Molecular Biology Grade. Pack Sizes: 10ml. US Biological Life Sciences. | Worldwide |
| Polystyrene, General-II, high strength | Insoluble in water and less dense than water. Contact may cause irritate skin, eyes, and mucous membranes. May be toxic by ingestion.;Styrene monomer, stabilized appears as a clear colorless to dark liquid with an aromatic odor. Vapors heavier than air and irritating to the eyes and mucous membranes. Subject to polymerization. If the polymerization takes place inside a closed container, the container may rupture violently. Less dense than water and insoluble in water. Used to make plastics, paints, and synthetic rubber.;GasVapor; Liquid; PelletsLargeCrystals; PelletsLargeCrystals, Liquid;Liquid;Liquid;COLOURLESS-TO-YELLOW OILY LIQUID.;COLOURLESS SOLID IN VARIOUS FORMS.;Colorless to yellow, oily liquid with a sweet, floral odor.;Colorless to yellow, oily liquid with a sweet, floral odor. Group: Polymers. CAS No. 9003-53-6. Product ID: styrene. Molecular formula: 104.15g/mol. Mole weight: C8H8;C6H5CHCH2;(C8H8)x;C8H8. C=CC1=CC=CC=C1. InChI=1S / C8H8 / c1-2-8-6-4-3-5-7-8 / h2-7H, 1H2. PPBRXRYQALVLMV-UHFFFAOYSA-N. | |
| Vanadium(III) chloride | Vanadium trichloride appears as a pink crystalline solid. Density 3.00 g / cm³. Irritates skin and eyes. Used to make other chemicals. Group: Electrolyteshydrogen storage materials. CAS No. 7718-98-1. Product ID: trichlorovanadium. Molecular formula: 157.3g/mol. Mole weight: VCl3;Cl3V. Cl[V](Cl)Cl. InChI=1S/3ClH.V/h3*1H;/q;;;+3/p-3. HQYCOEXWFMFWLR-UHFFFAOYSA-K. | |
| Vanadium(III) oxide | Vanadium trioxide appears as a black crystalline solid. Density 4.87 g / cm³. Slightly soluble in water. Irritating to skin and eyes. May be toxic by ingestion. Used to make other chemicals. Used as a catalyst.;DryPowder;BLACK POWDER. Group: Electrode materials solid oxide fuel cell materials. CAS No. 1314-34-7. Product ID: oxo(oxovanadiooxy)vanadium. Molecular formula: 149.881g/mol. Mole weight: V2O3;V2O3;O3V2. O=[V]O[V]=O. InChI=1S/3O.2V. KFAFTZQGYMGWLU-UHFFFAOYSA-N. | |
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