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This heme-thiolate (P-450) enzyme acts on a range of steroids with a 14α-methyl group, such as obtusifoliol and lanosterol. The enzyme catalyses two successive hydroxylations of the 14α-methyl group, followed by elimination as formate, leaving a 14(15) double bond. Group: Enzymes. Synonyms: obtusufoliol 14-demethylase; lanosterol 14-demethylase; lanosterol 14α-demethylase; sterol 14-demethylase. Enzyme Commission Number: EC 1.14.13.70. CAS No. 60063-87-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0877; sterol 14α-demethylase; EC 1.14.13.70; 60063-87-8; obtusufoliol 14-demethylase; lanosterol 14-demethylase; lanosterol 14α-demethylase; sterol 14-demethylase. Cat No: EXWM-0877.
sterol 22-desaturase
A heme-thiolate protein (P450). The enzyme, found in yeast and plants, catalyses the introduction of a double bond between the C-22 and C-23 carbons of certain sterols. In yeast the enzyme acts on ergosta-5,7,24(28)-trien-3β-ol, a step in the biosynthesis of ergosterol. The enzyme from the plant Arabidopsis thaliana acts on sitosterol and 24-epi-campesterol, producing stigmasterol and brassicasterol, respectively. Group: Enzymes. Synonyms: ERG5 (gene name); CYP710A (gene name). Enzyme Commission Number: EC 1.14.19.41. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1006; sterol 22-desaturase; EC 1.14.19.41; ERG5 (gene name); CYP710A (gene name). Cat No: EXWM-1006.
sterol 24-C-methyltransferase
Requires glutathione. Acts on a range of sterols with a 24(25)-double bond in the sidechain. While zymosterol is the preferred substrate it also acts on desmosterol, 5α-cholesta-7,24-dien-3β-ol, 5α-cholesta-5,7,24-trien-3β-ol, 4α-methylzymosterol and others. S-Adenosyl-L-methionine attacks the Si-face of the 24(25) double bond and the C-24 hydrogen is transferred to C-25 on the Re face of the double bond. Group: Enzymes. Synonyms: Δ24-methyltransferase; Δ24-sterol methyltransferase; zymosterol-24-methyltransferase; S-adenosyl-4-methionine:sterol Δ24-methyltransferase; SMT1; 24-sterol C-methyltransferase; S-adenosyl-L-methionine:Δ24(23)-sterol methyltransferase; phytosterol methyltransferase. Enzyme Commission Number: EC 2.1.1.41. CAS No. 37257-07-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1945; sterol 24-C-methyltransferase; EC 2.1.1.41; 37257-07-1; Δ24-methyltransferase; Δ24-sterol methyltransferase; zymosterol-24-methyltransferase; S-adenosyl-4-methionine:sterol Δ24-methyltransferase; SMT1; 24-sterol C-methyltransferase; S-adenosyl-L-methionine:Δ24(23)-sterol methyltransferase; phytosterol methyltransferase. Cat No: EXWM-1945.
sterol 3β-glucosyltransferase
Not identical with EC 2.4.1.192 (nuatigenin 3β-glucosyltransferase) or EC 2.4.1.193 (sarsapogenin 3β-glucosyltransferase). Group: Enzymes. Synonyms: UDPG:sterol glucosyltransferase; UDP-glucose-sterol β-glucosyltransferase; sterol:UDPG glucosyltransferase; UDPG-SGTase; uridine diphosphoglucose-poriferasterol glucosyltransferase; uridine diphosphoglucose-sterol glucosyltransferase; sterol glucosyltransferase; sterol-β-D-glucosyltransferase; UDP-glucose-sterol glucosyltransferase. Enzyme Commission Number: EC 2.4.1.173. CAS No. 123940-38-5,9075-00-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2398; sterol 3β-glucosyltransferase; EC 2.4.1.173; 123940-38-5,9075-00-7; UDPG:sterol glucosyltransferase; UDP-glucose-sterol β-glucosyltransferase; sterol:UDPG glucosyltransferase; UDPG-SGTase; uridine diphosphoglucose-poriferasterol glucosyltransferase; uridine diphosphoglucose-sterol glucosyltransferase; sterol glucosyltransferase; sterol-β-D-glucosyltransferase; UDP-glucose-sterol glucosyltransferase. Cat No: EXWM-2398.
sterol esterase
A group of enzymes of broad specificity, acting on esters of sterols and long-chain fatty acids, that may also bring about the esterification of sterols. Activated by bile salts. Group: Enzymes. Synonyms: cholesterol esterase; cholesteryl ester synthase; triterpenol esterase; cholesteryl esterase; cholesteryl ester hydrolase; sterol ester hydrolase; cholesterol ester hydrolase; cholesterase; acylcholesterol lipase. Enzyme Commission Number: EC 3.1.1.13. CAS No. 9026-00-0. Cholesterol Esterase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3440; sterol esterase; EC 3.1.1.13; 9026-00-0; cholesterol esterase; cholesteryl ester synthase; triterpenol esterase; cholesteryl esterase; cholesteryl ester hydrolase; sterol ester hydrolase; cholesterol ester hydrolase; cholesterase; acylcholesterol lipase. Cat No: EXWM-3440.
sterol O-acyltransferase
The animal enzyme is highly specific for transfer of acyl groups with a single cis double bond that is nine carbon atoms distant from the carboxy group. Group: Enzymes. Synonyms: cholesterol acyltransferase; sterol-ester synthase; sterol-ester synthetase; sterol-ester synthase; acyl coenzyme A-cholesterol-O-acyltransferase; acyl-CoA:cholesterol acyltransferase; ACAT; acylcoenzyme A:cholesterol O-acyltransferase; cholesterol ester synthase; cholesterol ester synthetase; cholesteryl ester synthetase. Enzyme Commission Number: EC 2.3.1.26. CAS No. 9027-63-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2203; sterol O-acyltransferase; EC 2.3.1.26; 9027-63-8; cholesterol acyltransferase; sterol-ester synthase; sterol-ester synthetase; sterol-ester synthase; acyl coenzyme A-cholesterol-O-acyltransferase; acyl-CoA:cholesterol acyltransferase; ACAT; acylcoenzyme A:cholesterol O-acyltransferase; cholesterol ester synthase; cholesterol ester synthetase; cholesteryl ester synthetase. Cat No: EXWM-2203.
24,25-Epoxycholesterol is sterol found in red alga Rissoella verruculosa and Galaxaura marginata and exhibits cytotoxicity toward several cancer cell lines. Group: Biochemicals. Grades: Highly Purified. CAS No. 72542-49-5. Pack Sizes: 500ug, 1mg. Molecular Formula: C27H44O2, Molecular Weight: 400.64. US Biological Life Sciences.
Worldwide
24-Hydroxycholesterol
24-Hydroxycholesterol, also known as 24-OH-Chol, a natural sterol, is the main cholesterol elimination product of the brain. 24-Hydroxycholesterol is a positive allosteric modulator of N-Methyl-d-Aspartate (NMDA) receptorsR, and a potent activator of the transcription factors LXR. 24-Hydroxycholesterol acts as a neurotoxin to SH-SY5Y human neuroblastoma cells which showed corresponding morphological changes: the cells became round, lost adhesion to the petri-dish, and neurite outgrowth degenerated. Synonyms: (3S,8S,9S,10R,13R,14S,17R)-17-[(2R)-5-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol; 24-hydroxycholesterol; 24S-hydroxycholesterol; cerebrosterol; cholest-5-ene-3,24-diol. CAS No. 30271-38-6. Molecular formula: C27H46O2. Mole weight: 402.65.
24-Hydroxycholesterol
24-Hydroxycholesterol is a natural sterol, which serves as a positive allosteric modulator of N-Methyl-d-Aspartate (NMDA) receptorsR , and a potent activator of the transcription factors LXR. Uses: Scientific research. Group: Natural products. CAS No. 30271-38-6. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg. Product ID: HY-N2370.
24-Methylenecholesterol
24-Methylenecholesterol (Ostreasterol), a natural marine sterol, stimulates cholesterol acyltransferase in human macrophages. 24-Methylenecholesterol possess anti-aging effects in yeast. 24-methylenecholesterol enhances honey bee longevity and improves nurse bee physiology [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Ostreasterol. CAS No. 474-63-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133968.
24-methylenesterol C-methyltransferase
This is the second methylation step of plant sterol biosynthesis (cf EC 2.1.1.142, cycloartenol 24-C-methyltransferase). Group: Enzymes. Synonyms: SMT2; 24-methylenelophenol C-241-methyltransferase. Enzyme Commission Number: EC 2.1.1.143. CAS No. 67165-89-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1739; 24-methylenesterol C-methyltransferase; EC 2.1.1.143; 67165-89-3; SMT2; 24-methylenelophenol C-241-methyltransferase. Cat No: EXWM-1739.
25(S)-27-Hydroxy cholesterol
25(S)-27-Hydroxy cholesterol, a sterol 27-hydroxylase-mediated cholesterol hydroxylation product, activates LXRα and LXRβ in vitro with EC50 values of 85 and 71 nM, respectively, and is a potent suppressor of cholesterol biosynthesis. Synonyms: (25S)-26-hydroxy cholesterol; 26-OHC. Grades: ≥95%. CAS No. 56845-83-1. Molecular formula: C27H46O2. Mole weight: 402.7.
27-Carboxy-7-keto Cholesterol
27-Carboxy-7-keto Cholesterol is a cytostatic sterol for treatment of cancer and other conditions associated with rapidly growing cells. Synonyms: (3β)-3-Hydroxy-7-oxocholest-5-en-26-oic Acid. Grades: > 95%. CAS No. 148988-30-1. Molecular formula: C27H42O4. Mole weight: 430.63.
27-Hydroxy-7-keto Cholesterol
27-Hydroxy-7-keto Cholesterol is a cytostatic sterol for treatment of cancer and other conditions associated with rapidly growing cells. Synonyms: (3β)-3,26-Dihydroxycholest-5-en-7-one. Grades: > 95%. CAS No. 148988-28-7. Molecular formula: C27H44O3. Mole weight: 416.64.
3-O-tert-Butyldimethylsilyl 7 β-Hydroxy Cholesterol-d7 is a derivative of 7α-Hydroxy Cholesterol-d7 (H917992), a metabolite of Cholesterol (C432501). 3-O-tert-Butyldimethylsilyl 7 β-Hydroxy Cholesterol-d7 is used in the preparation of deuterated isotopomers of sterols. Group: Biochemicals. Alternative Names: (3 β,7 β ) -3-[[ (1, 1-Dimethylethyl) dimethylsilyl]oxy]-cholest-5-en-7-ol. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
7-Dehydrocholesterol - Product ID: NST-10-88. Category: Sterols. Alternative Names: Cholesta-5,7-dien-3?-ol. Purity: 98%. Test method: HPLC. CAS No. 434-16-2. Pack Sizes: 5g, 10g, 25g, 50g. Appearance: White to beige colored Powder. Molecular formula: C27H44O. Mole weight: 384.65. Storage: +2 +8 °C.
7-dehydrocholesterol reductase
The enzyme is part of the cholesterol biosynthesis pathway. Group: Enzymes. Synonyms: DHCR7 (gene name); 7-DHC reductase; 7-dehydrocholesterol dehydrogenase/cholesterol oxidase; Δ7-sterol reductase. Enzyme Commission Number: EC 1.3.1.21. CAS No. 9080-21-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1296; 7-dehydrocholesterol reductase; EC 1.3.1.21; 9080-21-1; DHCR7 (gene name); 7-DHC reductase; 7-dehydrocholesterol dehydrogenase/cholesterol oxidase; Δ7-sterol reductase. Cat No: EXWM-1296.
7-Ketocholesterol
7-Ketocholesterol is a bioactive sterol and a major oxysterol component of oxidized LDL. It is also a metabolite of Cholesterol. Synonyms: (3β)-3-Hydroxycholest-5-en-7-one; 3β-Hydroxycholest-5-en-7-one; 7-Oxocholesterol; Cholest-5-en-3β-ol-7-one; 7-Oxocholesterol; 7-oxo-cholesterol. Grades: > 95%. CAS No. 566-28-9. Molecular formula: C27H44O2. Mole weight: 400.64.
8R-Brassicasterol is a by-product in the synthesis of Brassicasterol (B676850). Brassicasterol is a phytosterol found in canola oil, rapeseed oil, marine algae and shellfish. This compound has been shown to inhibit sterol Δ24-reductase, an enzyme involved in the mammalian cholesterol biosynthesis pathway. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C28H46O. US Biological Life Sciences.
Worldwide
β-Sitosterol
A common sterol in plants. Isolated from wheat germ oil, corn oil. Antilipemic. Used in the treatment of prostatic adenoma. 5-alpha reductase inhibitor. β-sitosterol reduces blood levels of cholesterol, and is sometimes used in treating hypercholesterolemia. β-Sitosterol inhibits cholesterol absorption in the intestine. When the sterol is absorbed in the intestine, it is transported by lipoproteins and incorporated into the cellular membrane. Group: Biochemicals. Alternative Names: (3 β)-Stigmast-5-en-3-ol; Nimbosterol; Stigmast-5-en-3 β-ol; (-)- β-Sitosterol; (24R)-Ethylcholest-5-en-3 β-ol; (24R)-Stigmast-5-en-3 β-ol. Grades: Highly Purified. CAS No. 83-46-5. Pack Sizes: 10mg, 25mg, 50mg. Molecular Formula: C29H50O, Molecular Weight: 414.71. US Biological Life Sciences.
Worldwide
Beta-Sitosterol (purity>80%)
Beta-Sitosterol (purity>80%) includes β-sitosterol (≥80%), stigmasterol, campesterol and brassicasterol mainly. Beta-Sitosterol is a plant sterol. Beta-Sitosterol (purity>80%) interfere with multiple cell signaling pathways, including cell cycle, apoptosis, proliferation, survival, invasion, angiogenesis, metastasis and inflammation [1]. Uses: Scientific research. Group: Natural products. CAS No. 83-46-5. Pack Sizes: 100 mg; 1 g; 5 g. Product ID: HY-N0171.
Brassicasterol
Brassicasterol is a metabolite of Ergosterol and has cardiovascular protective effects. Brassicasterol exerts anticancer effects in prostate cancer through dual targeting of AKT and androgen receptor signaling pathways. Brassicasterol inhibits HSV-1 ( IC 50 =1.2 μM) and Mycobacterium tuberculosis. Brassicasterol also inhibits sterol δ 24-reductase , slowing the progression of atherosclerosis. Brassicasterol is also a cerebrospinal fluid biomarker for Alzheimer's disease [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. CAS No. 474-67-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-113289.
Brassicasterol-(2,2',3,4,4',6-D6)
Brassicasterol-(2,2',3,4,4',6-D6) is derived from Brassicasterol (B676850), which is a phytosterol found in canola oil, rapeseed oil, marine algae and shellfish. This compound has been shown to inhibit sterol Δ24-reductase, an enzyme involved in the mammalian cholesterol biosynthesis pathway. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C28H40D6O, Molecular Weight: 404.7. US Biological Life Sciences.
Worldwide
Butchers Broom P.E. 22% Sterolic Heterosides UV
Butchers Broom P.E. 22% Sterolic Heterosides UV.
CA, FL & NJ
Campesterol
Campesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects. Uses: Scientific research. Group: Natural products. CAS No. 474-62-4. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N1459.
Chemically modified Pseudomonas species Cholesterol Esterase
Hydrolase that splits fatty acids from sterols. Take advantage of the enhanced stability of this enzyme in liquid reagents. Rely on the proven diagnostic quality of this product. Applications: Use cholesterol esterase, chemically modified in diagnostic tests for the determination of cholesterol in combination with cholesterol oxidase. Group: Enzymes. Synonyms: cholesterol esterase; cholesteryl ester synthase; triterpenol esterase; cholesteryl esterase; cholesteryl ester hydrolase; sterol ester hydrolase; cholesterol ester hydrolase; cholesterase; acylcholesterol lipase; sterol esterase; CE. Cholesterol Esterase. Mole weight: ~129 kD. Activity: >10 U/mg lyophilizate; >100 U/mg protein. Stability: At +2 to +8°C within specification range for 12 months. Store dry. Appearance: Brownish lyophilizate. Source: Pseudomonas species. cholesterol esterase; cholesteryl ester synthase; triterpenol esterase; cholesteryl esterase; cholesteryl ester hydrolase; sterol ester hydrolase; cholesterol ester hydrolase; cholesterase; acylcholesterol lipase; EC 3.1.1.13; 9026-00-0; sterol esterase; CE. Cat No: DIA-281.
Cholesterol
Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins [1] [2]. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist [3]. Uses: Scientific research. Group: Natural products. CAS No. 57-88-5. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-N0322.
Cholesterol
Cholesterol occurs as white or faintly yellow, almost odorless, pearly leaflets, needles, powder, or granules. On prolonged exposure to light and air, cholesterol acquires a yellow to tan color. Synonyms: Cholesterin; cholesterolum. CAS No. 57-88-5. Product ID: PE-0519. Molecular formula: C27H46O. Mole weight: 386.67. Category: Emollient; Emulsifying Agents. Product Keywords: Excipients for Liquid Dosage Form; Emulsifier Excipients; PE-0519; Cholesterol; Emollient; Emulsifying Agents; C27H46O; 57-88-5. UNII: 97C5T2UQ7J. Chemical Name: Cholest-5-en-3β-ol. Grade: Pharmceutical Excipients. Administration route: Injections; ophthalmic, topical, and vaginal. Dosage Form: Injections; ophthalmic, topical, and vaginal preparations. Stability and Storage Conditions: Cholesterol is stable and should be stored in a well-closed container, protected from light. Source and Preparation: The commercial material is normally obtained from the spinal cord of cattle by extraction with petroleum ethers, but it may also be obtained from wool fat. Purification is normally accomplished by repeated bromination. Cholesterol may also be produced by entirely synthetic means. Cholesterol produced from animal organs will always contain cholestanol and other saturated sterols. Applications: Cholesterol is used in cosmetics and topical pharmaceutical formulations at concentrations of 0.3-5.0% w/w as an emulsifying agent. It imparts water-absorbi
Cholesterol
Cholesterol - Product ID: NST-10-135. Category: Sterols. Alternative Names: (-)-Cholesterol, Cholesteryl alcohol, Dythol, Lidinit, Marine Cholesterol, Provitamin D. Purity: 98%. Test method: HPLC. CAS No. 57-88-5. Pack Sizes: 50g, 100g, 250g, 500g. Appearance: White to beige coloured Powder. Molecular formula: C27H46O. Mole weight: 386.66. Storage: +2 +8 °C.
Cholesterol-13C2
Cholesterol- 13 C 2 is the 13 C labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins [1] [2]. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist [3]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 78887-48-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N0322S5.
cholesterol 25-hydroxylase
Unlike most other sterol hydroxylases, this enzyme is not a cytochrome P-450. Instead, it uses diiron cofactors to catalyse the hydroxylation of hydrophobic substrates. The diiron cofactor can be either Fe-O-Fe or Fe-OH-Fe and is bound to the enzyme through interactions with clustered histidine or glutamate residues. In cell cultures, this enzyme down-regulates cholesterol synthesis and the processing of sterol regulatory element binding proteins (SREBPs). Group: Enzymes. Synonyms: cholesterol 25-monooxygenase. Enzyme Commission Number: EC 1.14.99.38. CAS No. 60202-07-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1049; cholesterol 25-hydroxylase; EC 1.14.99.38; 60202-07-5; cholesterol 25-monooxygenase. Cat No: EXWM-1049.
Cholesterol-25-Hydroxylase, Human (CH25H)
Cholesterol-25-Hydroxylase (CH25H) is an intronless gene that is involved in cholesterol and lipid metabolism. The encoded protein is a membrane protein and contains clusters of histidine residues essential for catalytic activity. Unlike most other sterol hydroxylases, this enzyme is a member of a small family of enzymes that utilize diiron cofactors to catalyze the hydroxylation of hydrophobic substrates. Group: Molecular Biology. Pack Sizes: 10ug, 50ug, 100ug. US Biological Life Sciences.
Worldwide
cholesterol 7-desaturase
The enzyme, characterized from several organisms including the worm Caenorhabditis elegans, the fly Drosophila melanogaster, and the ciliate Tetrahymena thermophila, is a Rieske oxygenase. In insects it participates in the the biosythesis of ecdysteroid hormones. The electrons are transferred from NAD(P)H via an electron transfer chain likely to include ferredoxin reductase and ferredoxin. The enzyme differs from regular desaturases, such as EC 1.14.19.20, 7-sterol 5(6)-desaturase, which are cytochrome b5-dependent and contain the three His-boxes that are typical to most desaturases. Group: Enzymes. Synonyms: nvd (gene name); daf-36 (gene name). Enzyme Commission Number: EC 1.14.19.21. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0984; cholesterol 7-desaturase; EC 1.14.19.21; nvd (gene name); daf-36 (gene name). Cat No: EXWM-0984.
Cholesterol-d4
Labeled Cholesterol. Cholesterol is the principal sterol of the higher animals. Cholesterol was found in all body tissues, especial in the brain, spinal cord, and in animal fats or oils. Cholesterol is the main constituent of gallstones. Group: Biochemicals. Alternative Names: Cholesterol-25,26,26,26-d4; (3 β)-. Grades: Highly Purified. CAS No. 956029-28-0. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Cholesterol-d6
Cholesterol-d 6 is the deuterium labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins [1] [2]. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist [3] [4]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 60816-17-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N0322S1.
Cholesterol-d6
Labeled Cholesterol. Cholesterol is the principal sterol of the higher animals. Cholesterol was found in all body tissues, especial in the brain, spinal cord, and in animal fats or oils. Cholesterol is the main constituent of gallstones. Group: Biochemicals. Alternative Names: Cholesterol-2,2,3,4,4,6-d6; (3 β)-Cholest-5-en-3-ol-d6; (3 β)-. Grades: Highly Purified. CAS No. 92543-08-3. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Cholesterol-d7
Cholesterol-d 7 is the deuterium labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins [1] [2]. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist [3]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 83199-47-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0322S.
Cholesterol-d7
Labeled Cholesterol. Cholesterol is the principal sterol of the higher animals. Cholesterol was found in all body tissues, especial in the brain, spinal cord, and in animal fats or oils. Cholesterol is the main constituent of gallstones. Group: Biochemicals. Alternative Names: Cholesterol-25,26,26,26,27,27,27-d7; (3 β)-Cholest-5-en-3-ol-d7; (3 β)-. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Cholesterol Dehydrogenase from Nocardia sp.
Cholesterol dehydrogenase is an enzyme that uses nicotinamide adenine dinucleotide/nicotinamide adenine dinucleotide phosphate (NAD(P)) as its cofactor in oxidizing cholesterol to form cholest-4-en-3-one. This enzyme oxidizes the hydroxyl group at the 3 position of the sterol ring to form a ketone. Group: Enzymes. Synonyms: Cholesterol Dehydrogenase; CDH. CAS No. 67775-34-2. Activity: 10U/mg-solid or more. Storage: at -20°C. Form: Freeze dried powder. Source: Nocardia sp. Cholesterol Dehydrogenase; CDH. Cat No: NATE-0892.
Cholesterol Esterase from Candida Rugosa
Cholesterol esterase (CE) is also known as cholesterol ester hydrolase. This enzyme catalyzes the following reaction: Sterol Ester --------> Sterol + Fatty Acid. Cholesterol esterase activity has been demonstrated in pancreas, intestine, liver and kidney. The enzyme is inactivated by proteolytic enzymes but stabilized by proteolytic enzyme inhibitors and by bile salts. Group: Enzymes. Synonyms: cholesterol esterase; cholesteryl ester synthase; triterpenol esterase; cholesteryl esterase; cholesteryl ester hydrolase; sterol ester hydrolase; cholesterol ester hydrolase; cholesterase; acylcholesterol lipase; sterol esterase; CE. Enzyme Commission Number: EC 3.1.1.13. CAS No. 9026-00-0. Purity: 0.9. Activity: 25-100 U/mg. Storage: Store at -20° C. Form: Freeze dried powder. Source: Candida Rugosa. cholesterol esterase; cholesteryl ester synthase; triterpenol esterase; cholesteryl esterase; cholesteryl ester hydrolase; sterol ester hydrolase; cholesterol ester hydrolase; cholesterase; acylcholesterol lipase; sterol esterase; CE. Cat No: NATE-1679.
Cholesterol Esterase from E. coli, Recombinant
Sterol esterase belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is steryl-ester acylhydrolase. This enzyme participates in bile acid biosynthesis. Group: Enzymes. Synonyms: cholesterol esterase; cholesteryl ester synthase; triterpenol esterase; cholesteryl esterase; cholesteryl ester hydrolase; sterol ester hydrolase; cholesterol ester hydrolase; cholesterase; acylcholesterol lipase; EC 3.1.1.13; Sterol esterase. Enzyme Commission Number: EC 3.1.1.13. CAS No. 9026-00-0. Cholesterol Esterase. Mole weight: ca. 54 kDa. Activity: > 5 U/mg lyophilizate. Appearance: Light yellow lyophilizate. Source: E. coli. Species: E. coli. cholesterol esterase; cholesteryl ester synthase; triterpenol esterase; cholesteryl esterase; cholesteryl ester hydrolase; sterol ester hydrolase; cholesterol ester hydrolase; cholesterase; acylcholesterol lipase; EC 3.1.1.13; Sterol esterase. Cat No: DIA-405.
Cholesterol Esterase from Microorganism
Cholesterol esterase (CE) is also known as cholesterol ester hydrolase. This enzyme catalyzes the following reaction: Sterol Ester --------> Sterol + Fatty Acid. Cholesterol esterase activity has been demonstrated in pancreas, intestine, liver and kidney. The enzyme is inactivated by proteolytic enzymes but stabilized by proteolytic enzyme inhibitors and by bile salts. Group: Enzymes. Synonyms: cholesterol esterase; cholesteryl ester synthase; triterpenol esterase; cholesteryl esterase; cholesteryl ester hydrolase; sterol ester hydrolase; cholesterol ester hydrolase; cholesterase; acylcholesterol lipase; EC 3.1.1.13; Sterol esterase. Enzyme Commission Number: EC 3.1.1.13. CAS No. 9026-00-0. Activity: 5.0U/mg-solid or more. Form: Freeze dried powder. Source: Microorganism. cholesterol esterase; cholesteryl ester synthase; triterpenol esterase; cholesteryl esterase; cholesteryl ester hydrolase; sterol ester hydrolase; cholesterol ester hydrolase; cholesterase; acylcholesterol lipase; EC 3.1.1.13; Sterol esterase. Cat No: DIA-135.
Cholesterol Esterase from Pseudomonas sp.
Cholesterol esterase (CE) is also known as cholesterol ester hydrolase. This enzyme catalyzes the following reaction: Sterol Ester --------> Sterol + Fatty Acid. Cholesterol esterase activity has been demonstrated in pancreas, intestine, liver and kidney. The enzyme is inactivated by proteolytic enzymes but stabilized by proteolytic enzyme inhibitors and by bile salts. Group: Enzymes. Synonyms: cholesterol esterase; cholesteryl ester synthase; triterpenol esterase; cholesteryl esterase; cholesteryl ester hydrolase; sterol ester hydrolase; cholesterol ester hydrolase; cholesterase; acylcholesterol lipase; EC 3.1.1.13; Sterol esterase. Enzyme Commission Number: EC 3.1.1.13. CAS No. 9026-00-0. Activity: 100U/mg-solid or more (containing approx. 40% of stabilizers). Form: Freeze dried powder. Source: Pseudomonas sp. cholesterol esterase; cholesteryl ester synthase; triterpenol esterase; cholesteryl esterase; cholesteryl ester hydrolase; sterol ester hydrolase; cholesterol ester hydrolase; cholesterase; acylcholesterol lipase; EC 3.1.1.13; Sterol esterase. Cat No: DIA-134.
Cholesterol Esterase from Schizophyllum commune
Cholesterol esterase (CE) is also known as cholesterol ester hydrolase. This enzyme catalyzes the following reaction: Sterol Ester --------> Sterol + Fatty Acid. Cholesterol esterase activity has been demonstrated in pancreas, intestine, liver and kidney. The enzyme is inactivated by proteolytic enzymes but stabilized by proteolytic enzyme inhibitors and by bile salts. Group: Enzymes. Synonyms: cholesterol esterase; cholesteryl ester synthase; triterpenol esterase; cholesteryl esterase; cholesteryl ester hydrolase; sterol ester hydrolase; cholesterol ester hydrolase; cholesterase; acylcholesterol lipase; EC 3.1.1.13; Sterol esterase. Enzyme Commission Number: EC 3.1.1.13. CAS No. 9026-00-0. Activity: 2.0 U/mg-solid or more (containing approx. 20% of stabilizers). Form: Freeze dried powder. Source: Schizophyllum commune. cholesterol esterase; cholesteryl ester synthase; triterpenol esterase; cholesteryl esterase; cholesteryl ester hydrolase; sterol ester hydrolase; cholesterol ester hydrolase; cholesterase; acylcholesterol lipase; EC 3.1.1.13; Sterol esterase. Cat No: DIA-133.
Cholesterol Esterase, PEG Modified
PEG (Polyethylene glycol) modified cholesterol esterase (PEG Cholesterol Esterase) isone of our premier cholesterol esterase conjugates. Cholesterol esterase is an enzyme that catalyzes the hydrolysis of cholesterol esters into their sterol components and fatty acids. Cholesterol esterase has clinical applications in the determination of serum cholesterol combined with other enzymes. PEG modified cholesterol esterase shows better stability with good reactivity. All our labeled cholesterol esterase products were performed under mild reaction conditions to retain their maximum bioactivity. These conjugates were further purified by chromatography to ensure adequate applications both in-vitro and in-vivo. Conjugate ration: 20~50 peg5000/monomer. solubility: soluble in aqueous buffer. Group: Enzymes. Synonyms: PEG Cholesterol Esterase; Cholesterol Esterase-polyethylene glycol; CE-polyethylene glycol; CE-PEG; PEG-CE; PEG-Cholesterol Esterase. Cholesterol Esterase. Mole weight: ~65 kD for monomer; 400 kD for hexamer. Activity: >300 units/g. Storage: Store at -20°C. Form: Lyophilized powder. Source: Porcine pancreas. Species: Porcine. PEG Cholesterol Esterase; Cholesterol Esterase-polyethylene glycol; CE-polyethylene glycol; CE-PEG; PEG-CE; PEG-Cholesterol Esterase; Cholesterol Esterase, PEG Modified. Cat No: NATE-1587.
Cholesterol oxidase, Microorganism
Cholesterol oxidase, Microorganism (ChOx) is a bacterial flavin oxidase containing FAD, commonly used in biochemical research. Cholesterol oxidase catalyzes the oxidation of the C(3)-OH group of cholesterol (and other sterols) to cholest-5-en-3-one and isomerizes it to cholest-4-en-3-one [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ChOx. CAS No. 9028-76-6. Pack Sizes: 100 U; 500 U; 1 KU. Product ID: HY-P2848.
Cholesterol (Standard)
Cholesterol (Standard) is the analytical standard of Cholesterol. This product is intended for research and analytical applications. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins [1] [2]. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist [3]. Uses: Scientific research. Group: Natural products. CAS No. 57-88-5. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-N0322R.
Daucosterol
Daucosterol is an orally active natural sterol compound, which has anti-inflammatory, anticancer and immunomodulatory activities. Daucosterol inhibits cancer cell proliferation by inducing autophagy through ROS-dependent manner. Daucosterol also inhibits colon cancer growth by inducing apoptosis, inhibiting cell migration and invasion and targeting caspase signalling pathway [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Eleutheroside A; β-Sitosterol β-D-glucoside. CAS No. 474-58-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N0410.
Δ14-sterol reductase
This enzyme acts on a range of steroids with a 14(15)-double bond. Group: Enzymes. Enzyme Commission Number: EC 1.3.1.70. CAS No. 69403-07-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1339; Δ14-sterol reductase; EC 1.3.1.70; 69403-07-2. Cat No: EXWM-1339.
Δ24(241)-sterol reductase
Acts on a range of steroids with a 24(241)-double bond. Group: Enzymes. Synonyms: sterol Δ24(28)-methylene reductase; sterol Δ24(28)-reductase. Enzyme Commission Number: EC 1.3.1.71. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1340; Δ24(241)-sterol reductase; EC 1.3.1.71; sterol Δ24(28)-methylene reductase; sterol Δ24(28)-reductase. Cat No: EXWM-1340.
Δ24-sterol reductase
Acts on a range of steroids with a 24(25)-double bond, including lanosterol, desmosterol and zymosterol. Group: Enzymes. Synonyms: lanosterol Δ24-reductase. Enzyme Commission Number: EC 1.3.1.72. CAS No. 9033-57-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1341; Δ24-sterol reductase; EC 1.3.1.72; 9033-57-2; lanosterol Δ24-reductase. Cat No: EXWM-1341.
Delta-5-Avenasterol
Delta-5-Avenasterol is an analog of Stigmasterol, which is a plant sterol that is used as a precursor in the synthesis of progesterone. It has antioxidant activity. Synonyms: Δ5-Avenasterol; (3β)-Stigmasta-5,24(28)-dien-3-ol; Stigmasta-5,24(28)-dien-3β-ol; 24(28)-Ethylidenecholest-5-en-3β-ol; 24-Ethylcholesta-5,24(28)-dien-3β-ol; 24-Ethylidenecholest-5-en-3β-ol; 24-Ethylidenecholesterol. Grades: > 95%. CAS No. 18472-36-1. Molecular formula: C29H48O. Mole weight: 412.71.
Delta-7-Avenasterol
Delta-7-Avenasterol is an analog of Stigmasterol, which is a plant sterol that is used as a precursor in the synthesis of progesterone. It has antioxidant activity. Synonyms: Δ7-Avenasterol; (3β,5α,24Z)-Stigmasta-7,24(28)-dien-3-ol; (24Z)-24-Ethyl-5α-cholesta-7,24(28)-dien-3β-ol; (24Z)-5α-Stigmasta-7,24(28)-dien-3β-ol; (Z)-5α-Stigmasta-7,24(28)-dien-3β-ol; 24Z-Ethylidenelathosterol; 3β-Hydroxy-5α-stigmasta-7,24(28)Z-diene; 5α-Stigm. Grades: > 95%. CAS No. 23290-26-8. Molecular formula: C29H48O. Mole weight: 412.71.
Δ7-sterol 5(6)-desaturase
This enzyme, found in eukaryotic organisms, catalyses the introduction of a double bond between the C5 and C6 carbons of the B ring of Δ7-sterols, to yield the corresponding Δ5,7-sterols. The enzymes from yeast, plants and vertebrates act on avenasterol, episterol, and lathosterol, respectively. The enzyme is located at the endoplasmic reticulum and is membrane bound. Group: Enzymes. Synonyms: lathosterol oxidase; Δ7-sterol Δ5-dehydrogenase; Δ7-sterol 5-desaturase; Δ7-sterol-C5(6)-desaturase; 5-DES; SC5DL (gene name); ERG3 (gene name). Enzyme Commission Number: EC 1.14.19.20. CAS No. 37255-37-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0983; Δ7-sterol 5(6)-desaturase; EC 1.14.19.20; 37255-37-1; lathosterol oxidase; Δ7-sterol Δ5-dehydrogenase; Δ7-sterol 5-desaturase; Δ7-sterol-C5(6)-desaturase; 5-DES; SC5DL (gene name); ERG3 (gene name). Cat No: EXWM-0983.
diacylglycerol-sterol O-acyltransferase
Cholesterol, sitosterol, campesterol and diacylglycerol can act as acceptors. Transfers a number of long-chain fatty acyl groups. Group: Enzymes. Synonyms: 1,2-diacyl-sn-glycerol:sterol acyl transferase. Enzyme Commission Number: EC 2.3.1.73. CAS No. 79586-23-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2253; diacylglycerol-sterol O-acyltransferase; EC 2.3.1.73; 79586-23-5; 1,2-diacyl-sn-glycerol:sterol acyl transferase. Cat No: EXWM-2253.
Ergosterol is the primary sterol found in fungi, with antioxidative, anti-proliferative, and anti-inflammatory effects. Uses: Scientific research. Group: Natural products. CAS No. 57-87-4. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-N0181.
Fucosterol
Fucosterol is a sterol isolated from algae, seaweed or diatoms. Fucosterol exhibits various biological activities, including antioxidant, anti-adipogenic, blood cholesterol reducing, anti-diabetic and anti-cancer activities [1] [2]. Fucosterol regulates adipogenesis via inhibition of PPARα and C/EBPα expression and can be used for anti-obesity agents development research [1]. Uses: Scientific research. Group: Natural products. CAS No. 17605-67-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N4103.
Fucosterol
Fucosterol is a sterol isolated from algae, seaweed or diatoms. Fucosterol exhibits various biological activities, including antioxidant, anti-adipogenic, blood cholesterol reducing, anti-diabetic and anti-cancer activities. Fucosterol regulates adipogenesis via inhibition of PPARα and C/EBPα expression and can be used for anti-obesity agents development research. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Powder. CAS No. 17605-67-3. Molecular formula: C29H48O. Mole weight: 412.69. Purity: 0.98. IUPACName: (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(E,2R)-5-propan-2-ylhept-5-en-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol. Canonical SMILES: CC=C(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C(C)C. Product ID: ACM17605673-1. Alfa Chemistry ISO 9001:2015 Certified.