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| Product | Description | |
|---|---|---|
| superoxide dismutase | A metalloprotein; also known as erythrocuprein, hemocuprein or cytocuprein. Enzymes from most eukaryotes contain both copper and zinc; those from mitochondria and most prokaryotes contain manganese or iron. Group: Enzymes. Synonyms: superoxidase dismutase; copper-zinc superoxide dismutase; Cu-Zn superoxide dismutase; ferrisuperoxide dismutase; superoxide dismutase I; superoxide dismutase II; SOD; Cu,Zn-SOD; Mn-SOD; Fe-SOD; SODF; SODS; SOD-1; SOD-2; SOD-3; SOD-4; hemocuprein; erythrocuprein; cytocuprein; cuprein; hepatocuprein. Enzyme Commission Number: EC 1.15.1.1. CAS No. 9054-89-1. SOD. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1063; superoxide dismutase; EC 1.15.1.1; 9054-89-1; superoxidase dismutase; copper-zinc superoxide dismutase; Cu-Zn superoxide dismutase; ferrisuperoxide dismutase; superoxide dismutase I; superoxide dismutase II; SOD; Cu,Zn-SOD; Mn-SOD; Fe-SOD; SODF; SODS; SOD-1; SOD-2; SOD-3; SOD-4; hemocuprein; erythrocuprein; cytocuprein; cuprein; hepatocuprein. Cat No: EXWM-1063. |  |
| Superoxide Dismutase | EC #232-943-0 EC#1.15.1.1. CAS No. 9054-89-1. Product ID: 2-08484. Mole weight: 32500. Purity: ≥3,000 units/mg protein. Properties: from bovine erythrocytes. |  |
| Superoxide Dismutase 2 from Human, Recombinant | SOD2 is part of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. SOD2 binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in SOD2 gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. SOD2 destroys radicals which are usually produced within the cells and which are toxic to biological systems. Group: Enzymes. Synonyms: Superoxide dismutase [Mn]; mitochondrial; IPOB; MNSOD; MVCD6. Enzyme Commission Number: EC 1.15.1.1. Purity: > 95% by SDS-PAGE. SOD. Mole weight: 24.4 kDa (219 aa, 25-222 aa + His Tag). Activity: > 1,200 units/mg. Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at - 20°C or -70°C. Avoid repeated freezing and thawing cycles. Form: Liquid. Source: E. coli. Species: Human. Superoxide dismutase [Mn]; mitochondrial; IPOB; MNSOD; MVCD6; Superoxide Dismutase 2; SOD-2; Mn-SOD; Mn Superoxide dismutase. Cat No: NATE-1658. | |
| Superoxide Dismutase 8,000u/g (Bovine) (SOD) | Superoxide Dismutase 8,000u/g (Bovine) (SOD). |  CA, FL & NJ |
| Superoxide Dismutase A from Bacterial, Recombinant | Superoxide dismutase, Mn, also known as sodA, is a member of the iron/manganese superoxide dismutase family. SodA destroys radicals which are normally produced within the cells and which are toxic to biological systems. It works by catalyzing the dismutation of the superoxide radical O2- to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase. Group: Enzymes. Enzyme Commission Number: EC 1.15.1.1. Purity: > 95% by SDS-PAGE. SOD. Mole weight: 25.2 kDa (226 aa, 1-206 aa + His Tag). Activity: >350 units/mg. Form: Liquid. Source: E. coli. Species: Bacterial. Cat No: NATE-1659. | |
| Superoxide Dismutase from Bovine, Recombinant | Superoxide dismutase (SOD) catalyzes the dismutation of superoxide radicals to hydrogen peroxide and molecular oxygen. SOD plays a critical role in the defense of cells against the toxic effects of oxygen radicals. SOD competes with nitric oxide (NO) for superoxide anion (which reacts with NO to form peroxynitrite), thereby SOD promotes the activity of NO. SOD has also been shown to suppress apoptosis in cultured rat ovarian follicles, neural cell lines, and transgenic mice by preventing the conversion of NO to peroxynitrate, an inducer of apoptosis. Sod from bovine erythr ocytes was the first sod to be found in mammalian tissues. before its enzymatic activity was disc...Superoxide dismutase has been used in a study to investigate where lipoproteins may affect the l-arginine-nitric oxide pathway. superoxide dismutase has also been used in a study to investigate the mass spectral evidence for carbonate-anion-radical-induced posttranslational modification of tryptophan to kynurenine in human cu, zn superoxide dismutase. the product has been used to develop an sod assay. this assay used dismutase-mediated inhibition of nadh-dependent nitroblue tetrazolium reduction. Group: Enzymes. Synonyms: Superoxide dismutases; EC 1.15.1.1; superoxidase dismutase; copper-zinc superoxide dismutase; Cu-Zn superoxide dismutase; ferrisuperoxide dismutase; s | |
| Superoxide Dismutase from Human, Recombinant | Superoxide dismutase (SOD) catalyzes the dismutation of superoxide radicals to hydrogen peroxide and molecular oxygen. SOD plays a critical role in the defense of cells against the toxic effects of oxygen radicals. SOD competes with nitric oxide (NO) for superoxide anion (which reacts with NO to form peroxynitrite), thereby SOD promotes the activity of NO. SOD has also been shown to suppress apoptosis in cultured rat ovarian follicles, neural cell lines, and transgenic mice by preventing the conversion of NO to peroxynitrate, an inducer of apoptosis. Group: Enzymes. Synonyms: Superoxide dismutase [Cu-Zn]; EC 1.15.1.1; SOD1; SOD; ALS; ALS1; IPOA. Enzyme Commission Number: EC 1.15.1.1. Purity: > 95% by SDS-PAGE. SOD. Mole weight: 16.8 kDa (monomer), 33.6 kDa (homodimer). Activity: ~40,000 U/mg. Storage: Store at -20°C. Form: Lyophilized powder. Source: E. coli. Species: Human. Superoxide dismutase [Cu-Zn]; EC 1.15.1.1; SOD1; SOD; ALS; ALS1; IPOA; Cu-Zn superoxide dismutase; Cu,Zn-SOD. Cat No: NATE-1657. | |
| Superoxide Dismutase (SOD) 1IU NBT-mg from Melon | Superoxide Dismutase (SOD) 1IU NBT-mg from Melon. | CA, FL & NJ |
| Bovine Superoxide dismutase-polyethylene glycol | Superoxide dismutases (SOD) are enzymes that alternately catalyze the dismutation (or partitioning) of the superoxide (O2-) radical into either ordinary molecular oxygen (O2) or hydrogen peroxide (H2O2). Superoxide is produced as a by-product of oxygen metabolism and, if not regulated, causes many types of cell damage. Hydrogen peroxide is also damaging, but less so, and is degraded by other enzymes such as catalase. Thus, SOD is an important antioxidant defense in nearly all living cells exposed to oxygen. One exception is Lactobacillus plantarum and related lactobacilli, which use a different mechanism to prevent damage from reactive (O2-). Group: Enzymes. Synonyms: PEG-SOD; Superoxide dismutase-polyethylene glycol; SOD-PEG. SOD. Activity: 11,000 units/mg SOD before conjugation; SOD/PEG ratio: 10-20 PEG with each SOD enzyme. Appearance: Off-white. Storage: Store at -20°C. Form: Lyophilized powder. Source: Bovine Kidney. Species: Bovine. PEG-SOD; Superoxide dismutase-polyethylene glycol; SOD-PEG. Cat No: NATE-0682. | |
| Cu/Zn Superoxide Dismutase, Recombinant | Superoxide dismutase (SOD) catalyzes the dismutation of superoxide radicals to hydrogen peroxide and molecular oxygen. SOD plays a critical role in the defense of cells against the toxic effects of oxygen radicals. SOD competes with nitric oxide (NO) for superoxide anion (which reacts with NO to form peroxynitrite), thereby SOD promotes the activity of NO. SOD has also been shown to suppress apoptosis in cultured rat ovarian follicles, neural cell lines, and transgenic mice by preventing the conversion of NO to peroxynitrate, an inducer of apoptosis. Superoxide dismutase (sod?ec 1.15.1.1) deal with the superoxide radical byalternately adding or removing an electron from t...c arthritis, myocardial infarction, angiocardiopathy, cancer patients. Group: Enzymes. Synonyms: Superoxide dismutases; EC 1.15.1.1; superoxidase dismutase; copper-zinc superoxide dismutase; Cu-Zn superoxide dismutase; ferrisuperoxide dismutase; superoxide dismutase I; superoxide dismutase II; SOD; Cu,Zn-SOD; Mn-SOD; Fe-SOD; SODF; SODS; SOD-1; SOD-2; SOD-3; SOD-4; hemocuprein; erythrocuprein; cytocuprein; cuprein ; hepatocuprein; 9054-89-1. Enzyme Commission Number: EC 1.15.1.1. Purity: >90% (SDS-PAGE test). Mole weight: About 20kDa (SDS-PAGE detection). Activity: 21,186U/mg protein. Appearance: White powder, lyophilized. Storage: 4°C, store at -20°C for long-term preserva | |
| Mn-Superoxide Dismutase, Recombinant | Superoxide dismutase (SOD) catalyzes the dismutation of superoxide radicals to hydrogen peroxide and molecular oxygen. SOD plays a critical role in the defense of cells against the toxic effects of oxygen radicals. SOD competes with nitric oxide (NO) for superoxide anion (which reacts with NO to form peroxynitrite), thereby SOD promotes the activity of NO. SOD has also been shown to suppress apoptosis in cultured rat ovarian follicles, neural cell lines, and transgenic mice by preventing the conversion of NO to peroxynitrate, an inducer of apoptosis. Superoxide dismutase (sod?ec 1.15.1.1) deals with the superoxide radical by alternately adding or removing an electron from t...ic arthritis, myocardial infarction, angiocardiopathy, cancer patients. Group: Enzymes. Synonyms: Superoxide dismutases; EC 1.15.1.1; superoxidase dismutase; copper-zinc superoxide dismutase; Cu-Zn superoxide dismutase; ferrisuperoxide dismutase; superoxide dismutase I; superoxide dismutase II; SOD; Cu,Zn-SOD; Mn-SOD; Fe-SOD; SODF; SODS; SOD-1; SOD-2; SOD-3; SOD-4; hemocuprein; erythrocuprein; cytocuprein; cuprein ; hepatocuprein; 9054-89-1. Enzyme Commission Number: EC 1.15.1.1. Purity: >90% (SDS-PAGE test). Mole weight: About 26kDa (SDS-PAGE detection). Activity: 15,528U/mg protein. Appearance: White powder, lyophilized. Storage: 4°C, store at -20°C for long-term preserva | |
| Native Bacillus stearothermophilus Superoxide Dismutase | Superoxide dismutase (SOD) catalyzes the dismutation of superoxide radicals to hydrogen peroxide and molecular oxygen. SOD plays a critical role in the defense of cells against the toxic effects of oxygen radicals. SOD competes with nitric oxide (NO) for superoxide anion (which reacts with NO to form peroxynitrite), thereby SOD promotes the activity of NO. SOD has also been shown to suppress apoptosis in cultured rat ovarian follicles, neural cell lines, and transgenic mice by preventing the conversion of NO to peroxynitrate, an inducer of apoptosis. Applications: The enzyme is useful for medicine, cosmetic material and nutrition or antioxidant. Group: Enzymes. Synonyms: Superoxide dismutases; EC 1.15.1.1; superoxidase dismutase;. Enzyme Commission Number: EC 1.15.1.1. CAS No. 9054-89-1. SOD. Mole weight: ca. 50,000; Subunit molecular weight : ca. 25,000. Appearance: Lyophilized. Storage: Stable at -20 °C for at least one year. Source: Bacillus stearothermophilus. Superoxide dismutases; EC 1.15.1.1; superoxidase dismutase; copper-zinc superoxide dismutase; Cu-Zn superoxide dismutase; ferrisuperoxide dismutase; superoxide dismutase I; superoxide dismutase II; SOD; Cu,Zn-SOD; Mn-SOD; Fe-SOD; SODF; SODS; SOD-1; SOD-2; SOD-3; SOD-4; hemocuprein; erythrocuprein; cytocuprein; cuprein ; hepatocuprein; 9054-89-1. Cat No: NATE-1910. | |
| Native Bovine Superoxide Dismutase | Superoxide dismutase (SOD) catalyzes the dismutation of superoxide radicals to hydrogen peroxide and molecular oxygen. SOD plays a critical role in the defense of cells against the toxic effects of oxygen radicals. SOD competes with nitric oxide (NO) for superoxide anion (which reacts with NO to form peroxynitrite), thereby SOD promotes the activity of NO. SOD has also been shown to suppress apoptosis in cultured rat ovarian follicles, neural cell lines, and transgenic mice by preventing the conversion of NO to peroxynitrate, an inducer of apoptosis. Group: Enzymes. Synonyms: Superoxide dismutases; EC 1.15.1.1; superoxidase dismutase; copper-zinc superoxide dismutase; Cu-Zn superoxide di. Enzyme Commission Number: EC 1.15.1.1. CAS No. 9054-89-1. SOD. Mole weight: mol wt 32.5 kDa. Activity: Type I, > 3 ,000 units/mg protein; Type II, > 4,500 units/mg protein; Type III, 2,500-7 ,000 units/mg protein. Storage: -20°C. Form: lyophilized powder. Source: Bovine erythrocytes. Species: Bovine. Superoxide dismutases; EC 1.15.1.1; superoxidase dismutase; copper-zinc superoxide dismutase; Cu-Zn superoxide dismutase; ferrisuperoxide dismutase; superoxide dismutase I; superoxide dismutase II; SOD; Cu,Zn-SOD; Mn-SOD; Fe-SOD; SODF; SODS; SOD-1; SOD-2; SOD-3; SOD-4; hemocuprein; erythrocuprein; cytocuprein; cuprein ; hepatocuprein; 9054-89-1. Cat No: NATE-0675. | |
| Native Canine Superoxide Dismutase | Superoxide dismutases (SOD) are enzymes that alternately catalyze the dismutation (or partitioning) of the superoxide (O2-) radical into either ordinary molecular oxygen (O2) or hydrogen peroxide (H2O2). Superoxide is produced as a by-product of oxygen metabolism and, if not regulated, causes many types of cell damage. Hydrogen peroxide is also damaging, but less so, and is degraded by other enzymes such as catalase. Thus, SOD is an important antioxidant defense in nearly all living cells exposed to oxygen. One exception is Lactobacillus plantarum and related lactobacilli, which use a different mechanism to prevent damage from reactive (O2-). Group: Enzymes. Synonyms: EC 1.15.1.1; 9054-89-1; SOD; Superoxide:superoxide oxidoreductase; Superoxide Dismutase. Enzyme Commission Number: EC 1.15.1.1. CAS No. 9054-89-1. SOD. Mole weight: mol wt ~31.2 kDa (two identical subunits). Activity: 2,000-6,000 units/mg protein. Stability: -20°C. Form: lyophilized powder. Source: canine erythrocytes. Species: Canine. EC 1.15.1.1; 9054-89-1; SOD; Superoxide:superoxide oxidoreductase; Superoxide Dismutase. Cat No: NATE-0677. | |
| Native Escherichia coli Superoxide Dismutase | Superoxide dismutase (SOD) catalyzes the dismutation of superoxide radicals to hydrogen peroxide and molecular oxygen. SOD plays a critical role in the defense of cells against the toxic effects of oxygen radicals. SOD competes with nitric oxide (NO) for superoxide anion (which reacts with NO to form peroxynitrite), thereby SOD promotes the activity of NO. SOD has also been shown to suppress apoptosis in cultured rat ovarian follicles, neural cell lines, and transgenic mice by preventing the conversion of NO to peroxynitrate, an inducer of apoptosis. Superoxide dismutases are a group of low molecular weight metalloproteins present in all aerobic cells of plants, animals...5.1.1; superoxidase dismutase; copper-zinc superoxide dismutase; Cu-Zn superoxide dismutase; ferrisuperoxide dismutase; superoxide dismutase I; superoxide dismutase II; SOD; Cu,Zn-SOD; Mn-SOD; Fe-SOD; SODF; SODS; SOD-1; SOD-2; SOD-3; SOD-4; hemocuprein; erythrocuprein; cytocuprein; cuprein ; hepatocuprein; 9054-89-1. Enzyme Commission Number: EC 1.15.1.1. CAS No. 9054-89-1. SOD. Mole weight: mol wt 32.5 kDa. Activity: > 1 ,000 units/mg protein. Storage: -20°C. Form: Lyophilized powder containing Tris buffer salts. Source: Escherichia coli. Superoxide dismutases; EC 1.15.1.1; superoxidase dismutase; copper-zinc superoxide dismutase; Cu-Zn superoxide dismutase; ferrisuper | |
| Native Horseradish Superoxide Dismutase | Superoxide dismutases (SOD) are enzymes that alternately catalyze the dismutation (or partitioning) of the superoxide (O2-) radical into either ordinary molecular oxygen (O2) or hydrogen peroxide (H2O2). Superoxide is produced as a by-product of oxygen metabolism and, if not regulated, causes many types of cell damage. Hydrogen peroxide is also damaging, but less so, and is degraded by other enzymes such as catalase. Thus, SOD is an important antioxidant defense in nearly all living cells exposed to oxygen. One exception is Lactobacillus plantarum and related lactobacilli, which use a different mechanism to prevent damage from reactive (O2-). Applications: Superoxide dism...mutase and glutathione reductase, and environmental and xenobiotic stress tolerance in maize inbreds. superoxide dismutase from horseradish has also been used in a study to investigate chemiluminometric enzyme sensors for flow-injection analysis. Group: Enzymes. Synonyms: EC 1.15.1.1; 9054-89-1; SOD; Superoxide:superoxide oxidoreductase; Superoxide Dismutase. Enzyme Commission Number: EC 1.15.1.1. CAS No. 9054-89-1. SOD. Activity: 1,000-4,000 units/mg protein. Stability: -20°C. Form: Lyophilized powder containing potassium phosphate buffer salts. Source: Horseradish. EC 1.15.1.1; 9054-89-1; SOD; Superoxide:superoxide oxidoreductase; Superoxide Dismutase. Cat No: NATE-0679. | |
| Native Human Superoxide Dismutase | Superoxide dismutase (SOD) catalyzes the dismutation of superoxide radicals to hydrogen peroxide and molecular oxygen. SOD plays a critical role in the defense of cells against the toxic effects of oxygen radicals. SOD competes with nitric oxide (NO) for superoxide anion (which reacts with NO to form peroxynitrite), thereby SOD promotes the activity of NO. SOD has also been shown to suppress apoptosis in cultured rat ovarian follicles, neural cell lines, and transgenic mice by preventing the conversion of NO to peroxynitrate, an inducer of apoptosis. Applications: Superoxide dismutase from human erythr ocytes has been used in a study to identify in vitro glycated sites of hu...-3; SOD-4; hemocuprein; erythrocuprein; cytocuprein; cuprein ; hepatocuprein; 9054-89-1. Enzyme Commission Number: EC 1.15.1.1. CAS No. 9054-89-1. SOD. Activity: > 2,500 units/mg protein. Storage: -20°C. Form: Lyophilized powder containing potassium phosphate buffer salts. Source: Human erythrocytes. Species: Human. Superoxide dismutases; EC 1.15.1.1; superoxidase dismutase; copper-zinc superoxide dismutase; Cu-Zn superoxide dismutase; ferrisuperoxide dismutase; superoxide dismutase I; superoxide dismutase II; SOD; Cu,Zn-SOD; Mn-SOD; Fe-SOD; SODF; SODS; SOD-1; SOD-2; SOD-3; SOD-4; hemocuprein; erythrocuprein; cytocuprein; cuprein ; hepatocuprein; 9054-89-1. Cat No: NATE-0680. | |
| Native Plant Superoxide Dismutase | Superoxide dismutase (SOD) catalyzes the dismutation of superoxide radicals to hydrogen peroxide and molecular oxygen. SOD plays a critical role in the defense of cells against the toxic effects of oxygen radicals. SOD competes with nitric oxide (NO) for superoxide anion (which reacts with NO to form peroxynitrite), thereby SOD promotes the activity of NO. SOD has also been shown to suppress apoptosis in cultured rat ovarian follicles, neural cell lines, and transgenic mice by preventing the conversion of NO to peroxynitrate, an inducer of apoptosis. Group: Enzymes. Synonyms: Superoxide dismutases; EC 1.15.1.1; copper-zinc superoxide dismutase; Cu-Zn superoxide dismutase; Cu,Zn-SOD; SOD. Enzyme Commission Number: EC 1.15.1.1. CAS No. 9054-89-1. SOD. Activity: 20,000u/g. Storage: at -4°C - 25°C, dry, dark conditions for 3 years. Form: Lyophilized powder. Source: Cactus. Superoxide dismutases; EC 1.15.1.1; copper-zinc superoxide dismutase; Cu-Zn superoxide dismutase; Cu,Zn-SOD; SOD. Cat No: NATE-1868. | |
| Native Porcine Superoxide Dismutase | Superoxide dismutase (SOD) is one kind of metalloenzyme, it can be used in antioxidization, fight against senium and improve the immunologic function. Superoxide dismutase(SOD) can be used in health care food, cosmetics and beer, etc. Group: Enzymes. Synonyms: Superoxide dismutases; EC 1.15.1.1; superoxidase dismutase; copper-zinc superoxide dismutase; Cu-Zn superoxide dismutase; ferrisuperoxide dismutase; superoxide dismutase I; superoxide dismutase II; SOD; Cu,Zn-SOD; Mn-SOD; Fe-SOD; SODF; SODS; SOD-1; SOD-2; SOD-3; SOD-4; hemocuprein; erythrocuprein; cytocuprein; cuprein; hepatocuprein; 9054-89-1. Enzyme Commission Number: EC 1.15.1.1. CAS No. 9054-89-1. SOD. Mole weight: 32KD. Activity: 4500 U/mg. Storage: 2 years in dry and low temperature. Form: light blue green powder. Source: Porcine. Species: Porcine. Superoxide dismutases; EC 1.15.1.1; superoxidase dismutase; copper-zinc superoxide dismutase; Cu-Zn superoxide dismutase; ferrisuperoxide dismutase; superoxide dismutase I; superoxide dismutase II; SOD; Cu,Zn-SOD; Mn-SOD; Fe-SOD; SODF; SODS; SOD-1; SOD-2; SOD-3; SOD-4; hemocuprein; erythrocuprein; cytocuprein; cuprein; hepatocuprein; 9054-89-1. Cat No: NATE-1925. | |
| Native Silphium perfoliatum L. Superoxide Dismutase | Superoxide dismutase (SOD) catalyzes the dismutation of superoxide radicals to hydrogen peroxide and molecular oxygen. SOD plays a critical role in the defense of cells against the toxic effects of oxygen radicals. SOD competes with nitric oxide (NO) for superoxide anion (which reacts with NO to form peroxynitrite), thereby SOD promotes the activity of NO. SOD has also been shown to suppress apoptosis in cultured rat ovarian follicles, neural cell lines, and transgenic mice by preventing the conversion of NO to peroxynitrate, an inducer of apoptosis. Applications: Mainly used in health food, cosmetics, medical drugs, biochemical agents supporting raw materials and additives. Group: Enzymes. Synonyms: Superoxide dismutases; EC 1.15.1.1; copper-zinc superoxide dismutase; Cu-Zn superoxide dismutase; Cu,Zn-SOD. Enzyme Commission Number: EC 1.15.1.1. CAS No. 9054-89-1. SOD. Mole weight: 32kD. Storage: at -4-25°C, dry, dark conditions for 3 years. Form: Light blue-green lyophilized powder. Source: Silphium perfoliatum L. Superoxide dismutases; EC 1.15.1.1; superoxidase dismutase; copper-zinc superoxide dismutase; Cu-Zn superoxide dismutase; Cu,Zn-SOD. Cat No: NATE-1619. | |
| SOD1 Inhibitor, LCS-1 (4,5-dichloro-2-(3-methylphenyl)-3(2H)-pyridazinone, 4,5-dichloro-2-m-tolylpyridazin-3(2H)-one, Superoxide Dismutase 1 Inhibitor, Lung Cancer Screen 1) | A 2-phenylpyridazin-3(2H)-one based non-copper chelater that selectively inhibits the activity of Superoxide dismutase 1 (Cu/Zn-SOD) (IC50=1.07uM). Cells over-expressing SOD1 show reduced sensitivity to LCS-1. Shown to preferably inhibit the growth of a variety of human lung adenocarinoma cell lines with EGFR and KRAS mutations (IC50=200nM). Prevents serum-induced activation of the ERK and PI 3-kinase/AKT signaling thereby affecting cell growth and survival. Apparent half-life of this compound is reported to be 6.6min in human liver microsomes. Group: Biochemicals. Grades: Highly Purified. CAS No. 41931-13-9. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| 2,3-Dimethylmaleic Anhydride | 2,3-Dimethylmaleic Anhydride. Uses: Reagent used in the synthesis of maleimides and as an amino group protecting agent for superoxide dismutase. Additional or Alternative Names: 3,4-dimethylfuran-2,5-dione; 3,4-dimethylfuran-2,5-dione. Product Category: Polymer/MacromoleculeAnhydride Monomers. Appearance: Off-White Solid. CAS No. 766-39-2. Molecular formula: C6H6O3. Mole weight: 126.11 g/mol. Purity: 0.98. Canonical SMILES: CC1=C(C)C(=O)OC1=O. ECNumber: 212-165-8. Product ID: ACM-MO-766392. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 2-Hydroxyethylhydrazine | 2-Hydroxyethylhydrazine is a reagent that is used in the preparation of dichlorophenoxymethyl-substituted pyrazolones and analogs as neuroprotectors against cytoxicity from protein aggregation of mutant superoxide dismutase 1. Group: Biochemicals. Grades: Highly Purified. CAS No. 109-84-2. Pack Sizes: 1g, 10 g. Molecular Formula: C2H8N2O. US Biological Life Sciences. | Worldwide |
| 2-Methoxyestradiol | 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. Alternative Names: 2-ME2; NSC-659853. CAS No. 362-07-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12033. |  |
| 2-Methoxyestradiol | 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-Me2. Product Category: Inhibitors. Appearance: Off-white solid. CAS No. 362-07-2. Molecular formula: C19H26O3. Mole weight: 302.41. Purity: 95%+. IUPACName: (8R,9S,13S,14S,17S)-2-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol. Canonical SMILES: CC12CCC3C(C1CCC2O)CCC4=CC(=C(C=C34)OC)O. Density: 1.178g/cm³. Product ID: ACM362072. Alfa Chemistry ISO 9001:2015 Certified. | |
| 4-Hydroxyisophthalic acid | 4-Hydroxyisophthalic acid activates antioxidant enzymes (such as catalase CAT and superoxide dismutase SOD ), scavenges free radicals, and exhibits antioxidant property. 4-Hydroxyisophthalic acid activates AChE and BChE , enhances neuronal function and improves Tau-induced neurobehavioral defects. 4-Hydroxyisophthalic acid improves the cognitive defects, and ameliorates circadian rhythm disorders of fruit flies [1]. Uses: Scientific research. Group: Natural products. CAS No. 636-46-4. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-76632. | |
| 6-Amino-5-nitroso-3-methyluracil-d3 | Possible inhibitor of Superoxide Dismutase. Group: Biochemicals. Alternative Names: 6-Amino-3-methyl-5-nitrosopyrimidine-2,4-dione-d3. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| AKV-9 | AKV-9 is the inhibitor for mutated Cu/Zn superoxide dismutase ( SOD1 ), that inhibits SOD1-induced protein aggregation and exhibits protective efficacy against SOD1-induced cytotoxicity in PC-12 with an EC 50 of 0.3 μM. AKV-9 ameliorates amyotrophic lateral sclerosis in mouse models and extends their lifespan [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1307262-15-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-169904. | |
| ATN-224 | ATN-224 is an oral Cu 2+ /Zn 2+ -superoxide dismutase 1 ( SOD1 ) inhibitor. ATN-224 inhibits SOD1 activity in endothelial cells, an effect that is dose dependent with an IC 50 of 17.5±3.7 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Bis(choline)tetrathiomolybdate. CAS No. 649749-10-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16074. | |
| ATN-224 | ATN-224 is an oral Cu2+/Zn2+ superoxide dismutase 1 (SOD1) inhibitor that inhibits SOD1 activity in endothelial cells in a dose-dependent manner with an IC50 of 17.5±3.7 nM. Synonyms: Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, (T-4)-tetrathioxomolybdate(2-) (2:1); 2-Hydroxy-N,N,N-trimethylethanaminium tetrathiomolybdate (2:1); ALXN 1840; ATN 224; ATN224; Bis(choline)tetrathiomolybdate; Tiomolibdate Choline; WTX 101; 2-Hydroxy-N,N,N-trimethylethan-1-aminium tetrathiomolybdate; Choline tetrathiomolybdate. Grades: ≥95%. CAS No. 649749-10-0. Molecular formula: C5H14NO.1/2MoS4. Mole weight: 432.54. |  |
| Avarol | Antibacterial against selected Gram-positive strains, antifungal. Anticancer compound. Antileukemic. Antimitotic agent. Antiviral compound. Inhibits HIV activity. Anti-inflammatory. Synovial phospholipase A2, cyclooxygenase and lipoxygenase inhibitor. Modulator of superoxide dismutase and glutathione peroxidase. Platelet aggregation inhibitor. Anti-psoriatic, mediated by inhibition of TNF-alpha generation and NF-kappaB activation. Group: Biochemicals. Alternative Names: NSC 306951. Grades: Highly Purified. CAS No. 55303-98-5. Pack Sizes: 1mg. Molecular Formula: C21H30O2. US Biological Life Sciences. | Worldwide |
| Avasopasem manganese | Avasopasem manganese (GC4419; M-40419) is a potent superoxide dismutase mimetic that rapidly and specifically converts O 2 *- to hydrogen peroxide (H 2 O 2 ), arresting the initiation of this cascade. Avasopasem manganese can be used for the research of severe oral mucositis (SOM) and cancer [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GC-4419; M-40419. CAS No. 435327-40-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109110. | |
| CORM-3 | CORM-3 is a water-soluble carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity. It attenuates NF-κB p65 nuclear translocation, reduces ROS generation and enhances intracellular glutathione and superoxide dismutase levels. Synonyms: Tricarbonylchloro (glycinato)ruthenium; (OC-6-44)-Tricarbonylchloro(glycinato-κN,κO)ruthenium; CORM3; CORM 3. Grades: >98%. CAS No. 475473-26-8. Molecular formula: C5H4ClNO5Ru. Mole weight: 294.61. | |
| Deacetylasperulosidic Acid | Deacetylasperulosidic acid (DAA) is a major phytochemical constituent of Morinda citrifolia fruit. Deacetylasperulosidic acidhas antioxidant activity by increasing superoxide dismutase activity. Deacetylasperulosidic acid has anticlastogenic activity, suppressing the induction of chromosome aberrations in hamster ovary cells and mice [1]. Deacetylasperulosidic acid prevents 4-nitroquinoline 1-oxide (4NQO) induced DNA damage in vitro, suppresses IL-2 production along with the activation of natural killer cells [2]. Uses: Scientific research. Group: Natural products. CAS No. 14259-55-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N0594. | |
| EUK-118 ((acetato- kO)[[2, 2'- [1, 2- ethanediylbis[(nitrilo- κ N)methylidyne]]bis[3, 5- dimethoxyphenolato- κO]](2- )]- manganese) | A structural analog of EUK 8 and EUK 134 with significantly reduced activity. Acts as a synthetic catalytic scavenger of reactive oxygen species with superoxide dismutase (SOD) and catalase mimetic activity. Superoxide-mediated reduction of an electron acceptor (i.e., SOD mimetic activity) was inhibited by EUK 118 with an IC50 value of 2.0um. Group: Biochemicals. Grades: Highly Purified. CAS No. 186299-34-3. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| EUK-124 (chloro[[2, 2- [1, 2- ethanediylbis[(nitrilo- κN)methylidyne) | A structural analog of EUK 8 and EUK 134 with significantly reduced activity. Acts as a synthetic catalytic scavenger of reactive oxygen species with superoxide dismutase (SOD) and catalase mimetic activity. EUK 124 inhibits superoxide-mediated reduction of an electron acceptor (i.e., SOD mimetic activity), with an IC?? value of 5.0um. Group: Biochemicals. Grades: Highly Purified. CAS No. 186299-35-4. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| EUK 134 | EUK 134, a synthetic superoxide dismutase (SOD)/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amyloid fibril. Synonyms: Acetorphan; EUK-134; EUK134. Grades: >98%. CAS No. 81065-76-1. Molecular formula: C18H18ClMnN2O4. Mole weight: 416.74. | |
| EUK-134 | EUK-134, a synthetic superoxide dismutase and catalase mimetic, protects rat kidneys from ischemia-reperfusion-induced damage. EUK-134 is a superoxide dismutase ( SOD ) mimetics (SODm) with catalase activity. EUK-134 is a mitoprotective antioxidant. EUK-134 reduces the expression of NF-κB , MDA level, and protein carbonylation in H9C2 cells [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 81065-76-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100594. | |
| EUK-134 (chloro[[2, 2'- [1, 2- ethanediylbis[(nitrilo- κ N)methylidyne]]bis[6- methoxyphenolato- κO]]]- manganese) | A synthetic superoxide dismutase (SOD)/catalase mimetic. EUK 134 is a salen-manganese complex that has been modified to increase its catalase activity while retaining SOD activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 81065-76-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Imisopasem manganese | Imisopasem manganese is a manganese-based non-peptidyl mimetic of the human mitochondrial manganese superoxide dismutase (MnSOD), with potential antioxidant and chemo/radioprotective activities. Upon administration, imisopasem manganese mimics the activity of MnSOD and scavenges reactive oxygen species (ROS), such as superoxide anion, which prevents oxygen free radical damage to macromolecules such as DNA. Synonyms: M40403; M 40403; M 40403; CG4419; CG 4419; CG-4419; SC-72325; SC72325; SC 72325. Grades: >98%. CAS No. 218791-21-0. Molecular formula: C21H35Cl2MnN5. Mole weight: 483.39. | |
| L-Carnosine (Standard) | L-Carnosine (Standard) is the analytical standard of L-Carnosine. This product is intended for research and analytical applications. L-Carnosine is a dipeptide of the amino acids beta-alanine and histidine and has the potential to suppress many of the biochemical changes that accompany aging. In Vitro: L-Carnosine is a dipeptide of the amino acids beta-alanine and histidine and has the potential to suppress many of the biochemical changes that accompany aging [1]. L-Carnosine also exhibits some antioxidant effects. The antioxidant mechanism of L-Carnosine is attributed to its chelating effect against metal ions, superoxide dismutase (SOD)-like activity, and ROS and free radicals scavenging ability [2]. Uses: Scientific research. Group: Peptides. CAS No. 305-84-0. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W013494R. | |
| LCS-1 | LCS-1 is an inhibitor superoxide dismutase 1 (SOD1) inhibitor, catalyzing the conversion of superoxide ion (O2-) into H2O2 and O2 to maintain low levels of reactive oxygen species. LCS-1 can prevent serum-induced activation of the ERK and PI 3-kinase/AKT signaling pathways and inhibit the proliferation of lung adenocarcinoma cell lines. Synonyms: LCS-1; LCS 1; LCS1; 4,5-Dichloro-2-(m-tolyl)pyridazin-3(2H)-one; 4,5-Dichloro-2-(3-methylphenyl)pyridazin-3-one. Grades: 99%. CAS No. 41931-13-9. Molecular formula: C11H8Cl2N2O. Mole weight: 255.1. | |
| LCS-1 | LCS-1 is a superoxide dismutase 1 ( SOD1 ) inhibitor. LCS-1 inhibits SOD1 activity with an IC 50 value of 1.07 μM. LCS-1 induces the early- and late-stage apoptosis of multiple myeloma (MM.1S) cells [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 41931-13-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115445. | |
| Levamlodipine besylate | Levamlodipine besylate ((S)-Amlodipine besylate) is an orally active calcium channel blocker with antioxidant and vasodilatory properties. Levamlodipine besylate can reduce serum malondialdehyde (MDA) levels, increase superoxide dismutase (SOD) activity, and improve oxidative stress. Levamlodipine besylate can be used for research on vascular dementia, hypertension, and cerebrovascular diseases [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (S)-Amlodipine besylate; Levoamlodipine besylate. CAS No. 150566-71-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14744A. | |
| MnTBAP chloride | Cell permeable superoxide dismutase (SOD) mimetic. Potent inhibitor of peroxynitrite-induced oxidative reactions (peroxynitrite scavenger), but not a scavenger of nitric oxide (NO). Neuronal apoptosis inhibitor. Protects T cells from superoxide generation, caspase-dependent DNA loss and cell death. Lipopolysaccharide-induced TNF-alpha production inhibitor, by prevention of intracellular ROS generation and subsequent inactivation of p38 MAPK and SAPK/JNK. Group: Biochemicals. Alternative Names: Manganese (III) tetrakis (4-benzoic acid)porphyrin chloride. Grades: Highly Purified. CAS No. 55266-18-7. Pack Sizes: 10mg, 50mg. Molecular Formula: C48H28MnN4O8Cl. US Biological Life Sciences. | Worldwide |
| MnTMPyP pentachloride | Cell permeable superoxide dismutase (SOD) mimetic. Peroxynitrite scavenger. Displays a protective effect against H2O2 mediated injury. Neuroprotective. Oxidative stress inhibitor. Apoptosis inhibitor. Reduces inflammation. Group: Biochemicals. Grades: Highly Purified. CAS No. 100012-18-8. Pack Sizes: 10mg, 50mg. Molecular Formula: C44H36MnN8Cl5. US Biological Life Sciences. | Worldwide |
| Oroxylin A | Oroxylin A is a natural active flavonoid with strong anticancer effects.IC50 value:Target:In vitro: Oroxylin A suppressed the MDM2-mediated degradation of p53 via downregulating MDM2 transcription in wt-p53 cancer cells. Oroxylin A remarkably reduced the generation of lactate and glucose uptake under hypoxia in HepG2 cells, inhibited HIF-1α expression and its stability. Oroxylin A promotes superoxide dismutase (SOD2) gene expression through SIRT3-regulated DNA-binding activity of FOXO3a and increases the activity of SOD2 by promoting SIRT3-mediated deacetylation.In vivo: Oroxylin A inhibited the tumor growth of nude mice-inoculated MCF-7 or HCT116 cells. The expression of MDM2 protein in tumor tissue was downregulated by oroxylin A as well. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid. CAS No. 480-11-5. Molecular formula: C16H12O5. Mole weight: 284.26. Purity: 0.9987. Canonical SMILES: O=C1C=C(C2=CC=CC=C2)OC3=CC(O)=C(OC)C(O)=C13. Product ID: ACM480115. Alfa Chemistry ISO 9001:2015 Certified. | |
| RTA-408 | RTA-408 is a member of the synthetic oleanane triterpenoid class of compounds and an activator of nuclear factor erythroid 2 [NF-E2]-related factor 2 (Nrf2, Nfe2l2), with potential chemopreventive activity. Upon administration, RTA 408 activates the cytoprotective transcription factor Nrf2. In turn, Nrf2 translocates to the nucleus, dimerizes with a small Maf protein (sMaf), and binds to the antioxidant response element (ARE). This induces the expression of a number of cytoprotective genes, including NAD(P)H quinone oxidoreductase 1 (NQO1), sulfiredoxin 1 (Srxn1), heme oxygenase-1 (HO1, HMOX1), superoxide dismutase 1 (SOD1), gamma-glutamylcysteine synthetase (gamma-GCS), thioredoxin reductase-1 (TXNRD1), glutathione S-transferase (GST), glutamate-cysteine ligase catalytic subunit (Gclc) and glutamate-cysteine ligase regulatory subunit (Gclm), and increases the synthesis of the antioxidant glutathione (GSH). Nrf2, a leucine zipper transcription factor, plays a key role in the maintenance of redox balance and cytoprotection against oxidative stress. Synonyms: RTA408; RTA408; RTA-408. Omaveloxolone; Propanamide, N-(2-cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoro-. Grades: >98%. CAS No. 1474034-05-3. Molecular formula: C33H44F2N2O3. Mole weight: 554.723. | |
| Rucosopasem Manganese | Rucosopasem manganese is a superoxide dismutase (SOD) mimic. Synonyms: FW5T90VM32; GC-4419 dipropionate; Bis-propionato(gc4419); Avasopasem manganese dipropionate. Grades: >98%. CAS No. 2248030-85-3. Molecular formula: C27H45MnN5O4. Mole weight: 558.6. | |
| Sodium Diethyldithiocarbamate-d10 | An inhibitor of superoxide dismutase, having both antioxidant and oxidant effects. Group: Biochemicals. Alternative Names: N,N-Diethyl-carbamodithioic Acid-d10 Sodium Salt; Diethyldithio-carbamic Acid-d10 Sodium Salt; Dithiocarb-d10; Dithiocarb-d10 sodium; Ditiocarb-d10 sodium; Imuthiol-d10; Kupral-d10; Soxinol ESL-d10; Thiocarb-d10. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Superoxide oxidoreductase | Synonyms: ORGOTEIN; Superoxide dismutases; SOD. CAS No. 9054-89-1. | |
| Tempol | Tempol is a general superoxide dismutase (SOD)-mimetic agent that efficiently neutralizes reactive oxygen species (ROS). Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4-Hydroxy-TEMPO. CAS No. 2226-96-2. Pack Sizes: 10 mM * 1 mL; 200 mg; 1 g. Product ID: HY-100561. | |
| Zineb | Zineb is an agricultural fungicide of the dithiocarbamate class. Its toxicity is relatively low, and there is little evidence of human harm from exposure. Oxidative stress is one of the main factors contributing to diseases caused by Zineb. Zineb does not alter the activity of any superoxide dismutase enzymes. Catalase (CAT) activity was reduced only by Zineb. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Zinc ethylene-1, 2-bisdithiocarbamate. CAS No. 12122-67-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W127739. | |
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