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| Product | Description | |
|---|---|---|
| T-2 Toxin | T-2 toxin is a common trichothecene mycotoxin produced by Fusarium species, which can infect grain crops causing alimentary toxic aleukia in humans and animals. It triggers a ribotoxic response through its high binding affinity to peptidyl transferase, which is an integral part of the 60S ribosomal subunit, resulting in activation of JNK/p38 MAPKs, interferes with the metabolism of membrane phospholipids, and increases liver lipid peroxides.1 T-2 toxin is highly cytotoxic to macrophages, inducing apoptosis in primary porcine alveolar macrophage cells with an IC50 value of 19.47 nM. At 3 nM it decreases the production of inflammatory mediators (IL-1 β, TNFα, and nitric oxide), TLR4, and TLR2/6 agonists.2. Group: Biochemicals. Alternative Names: (3α,4 β,8α)-12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol 4,15-Diacetate 8-(3-Methylbutanoate); 12,13-Epoxytrichothec-9-ene-3α,4 β,8α,15-tetrol 4,15-Diacetate 8-Isovalerate; 4 β,15-Diacetoxy-8α-(3-methylbutyryloxy)-12,13-epoxytrichothec-9-en-3α-ol; 8α-(3-Methylbutyryloxy)-4 β,15-diacetoxyscirp-9-en-3α-ol; Fusariotoxin T 2; Insariotoxin; Mycotoxin T 2; NSC 138780; T 2; T 2 mycotoxin; T-2 Lienomycin; Toxin T 2. Grades: Highly Purified. CAS No. 21259-20-1. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. |  Worldwide |
| T-2 Toxin Triol | T-2 Toxin Triol is a type-A trichothecene mycotoxin produced by Fusarium, itself a metabolite of T-2 Toxin. Group: Biochemicals. Alternative Names: (3α,4 β,8α)-12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol 8-(3-Methylbutanoate); 12,13-Epoxytrichothec-9-ene-3α,4 β,8α,15-tetrol 8-Isovalerate; Deacetyl HT 2 Toxin; T 2 Triol; Toxin T 2 Triol; Toxin T 3. Grades: Highly Purified. CAS No. 34114-98-2. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| HT-2 toxin | HT-2 toxin is a mycotoxin produced by Fusarium sp. Symptoms of poisoning are nausea, vomiting, diarrhea, and leukopenia. The acute toxicity is lower than trichothecene. Uses: This product is used as a reference standard in quantitative analysis of food stuffs. Synonyms: Mycotoxin HT 2; Toxin HT 2. CAS No. 26934-87-2. Molecular formula: C22H32O8. Mole weight: 424.48. |  |
| HT-2 Toxin | HT-2 Toxin is a trichothecene group mycotoxin. HT-2 Toxin is the 4-hydroxy analogue of T-2 Toxin which has been shown to induce DNA damage and cell death on prolonged administration. Group: Biochemicals. Alternative Names: (3α,4 β,8α)-12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol 8-(3-Methylbutanoate) 15-Acetate; 12,13-Epoxytrichothec-9-ene-3α,4 β,8α,15-tetro 15-Acetate 8-Isovalerate; 3,4-Dihydroxy-15-acetoxy-8-(3-methylbutyryloxy)-12,13-epoxy-Δ9-trichothecene; Isovaleric Acid 8-Ester with 12,13-epoxytrichothec-9-ene-3α,4 β,8α,15-tetrol 15-Acetate; HT 2; HT 2 Toxin; Mycotoxin HT 2; NSC 278571; Toxin HT 2. Grades: Highly Purified. CAS No. 26934-87-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 2-Methylthiazolidine-4-carboxylic Acid | 2-Methylthiazolidine-4-carboxylic Acid is an indispensable compound within the compound sector, used in studying diverse afflictions encompassing diabetes and its concomitant intricacies. Uses: An cysteine prodrug, protective aginst the fungal t-2 toxin. it is also a precursor to pharmaceuticals used in the treatment of cataracts. Synonyms: 2-Methyl-4-thiazolidinecarboxylic Acid; 4-Thiazolidinecarboxylic acid, 2-methyl-. Grade: 96%. CAS No. 4165-32-6. Molecular formula: C5H9NO2S. Mole weight: 147.20. | |
| 2-Methylthiazolidine-4-carboxylic Acid | An Cysteine prodrug, protective aginst the fungal T-2 toxin. It is also a precursor to pharmaceuticals used in the treatment of cataracts. Group: Biochemicals. Alternative Names: 2-Methyl-4-thiazolidinecarboxylic Acid. Grades: Highly Purified. CAS No. 4165-32-6. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| 5'-DMT-2'-deoxyguanosine (N-PAC) | N-PAC, also referred to as 5'-DMT-2'-deoxyguanosine, proves to be an insightful compound when investigating the impact of carcinogens on DNA. Its usage in biomedicine offers deeper comprehension of tobacco smoke's effects on genetic material, as well as other environmental toxins that may lead to illnesses such as cancer. Grade: ≥ 98% by HPLC. Molecular formula: C39H37N5O8. Mole weight: 703.74. | |
| Native Bacillus cereus Phospholipase C | Phospholipase C is an enzyme with system name phosphatidylcholine cholinephosphohydrolase. This enzyme catalyses the following chemical reaction: a phosphatidylcholine + H2O<-> 1, 2-diacyl-sn-glycerol + phosphocholine. The bacterial enzyme is a zinc protein. It also acts on sphingomyelin and phosphatidylinositol. Native phospholipase c (ec 3.1.4.3) was purified from bacillus cereus. Applications: Useful for enzymatic determination of lecithin. Group: Enzymes. Synonyms: Phospholipase C; EC 3.1.4.3; lipophosphodiesterase I; Clostridium welchii alpha-toxin; Clostridium oedematiens beta-and gamma-toxins; lipophosphodiesterase C; phosphatidase C; heat-labile hemolysin; alpha-toxin. Enzyme Commission Number: EC 3.1.4.3. CAS No. 9001-86-9. Phospholipase C. Activity: > 30 U/mg. Appearance: White to brownish powder. Storage: Store in tightly closed containers, desiccated, protected from light, at-20°C. Form: Freeze dried powder. Source: Bacillus cereus. Phospholipase C; EC 3.1.4.3; lipophosphodiesterase I; Clostridium welchii alpha-toxin; Clostridium oedematiens beta-and gamma-toxins; lipophosphodiesterase C; phosphatidase C; heat-labile hemolysin; alpha-toxin. Cat No: DIA-163. |  |
| NT-2 | NT-2 is a toxin produced by Fusarium sporotrichioides M-1. Molecular formula: C19H26O8. Mole weight: 382.4. | |
| T2 Toxin Triol | The 100 ppm acetonitrile solution of T2 Triol toxin, a kind of type-A trichothecene mycotoxin, could be used as standard solution. Synonyms: Scirpentriol; T-2 triol; Trichothec-9-ene-3-α,4-β,8-α,15-tetrol, 12,13-epoxy-, 8-isovalerate; T2 Triol Toxin; Toxin T-2 triol; Deacetyl-HT-2 toxin; 12,13-Epoxytrichothec-9-ene-3-alpha,4-beta,8-alpha,15-tetrol 8-isovalerate; Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 8-(3-methylbutanoate), (3alpha,4beta,8alpha)-. Grade: ≥95%. CAS No. 97373-21-2. Molecular formula: C20H30O7. Mole weight: 382.45. | |
| 17-AEP-GA | 17-AEP-GA, an ADC toxin and HSP90 antagonist, is a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion. Synonyms: Geldanamycin, 17-demethoxy-17-[[2-(1-pyrrolidinyl)ethyl]amino]-; 17-(2-(pyrrolidin-1-yl)ethyl)amino-17-demethoxygeldanamycin; 2-Azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione, 9-[(aminocarbonyl)oxy]-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-19-[[2-(1-pyrrolidinyl)ethyl]amino]-, (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-. Grade: >98.0%. CAS No. 75747-23-8. Molecular formula: C34H50N4O8. Mole weight: 642.78. | |
| 18:1 Ether Coenzyme A Ammonium salt | 18:1 Ether Coenzyme A Ammonium salt, a crucial ingredient in synthesizing glycosphingolipids and phospholipids, holds an instrumental position in the oxidative disposal of fatty acids while also being a vital agent for drug and toxin metabolism. It is a medically potent recourse for lipid abnormalities and certain inherited metabolic disorders, offering a path of primacy for therapeutic intervention. Synonyms: (9Z-octadecenyl) Coenzyme A (ammonium salt); triazanium (2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-(((((((R)-3-hydroxy-2,2-dimethyl-4-((3-((2-(((Z)-octadec-9-en-1-yl)thio)ethyl)amino)-3-oxopropyl)amino)-4-oxobutoxy)oxidophosphoryl)oxy)oxidophosphoryl)oxy)methyl)tetrahydrofuran-3-yl hydrogen phosphate; 9H-Purin-6-amine, 9-[(2ξ)-5-O-[hydroxy[[hydroxy[(3R)-3-hydroxy-2,2-dimethyl-4-[[3-[[2-[(9Z)-9-octadecen-1-ylthio]ethyl]amino]-3-oxopropyl]amino]-4-oxobutoxy]phosphinyl]oxy]phosphinyl]-3-O-phosphono-β-D-threo-pentofuranosyl]-, triammonium salt. Grade: >99%. CAS No. 2260670-62-8. Molecular formula: C39H79N10O16P3S. Mole weight: 1068.46. | |
| 1-Ethyl-4-isobutylbenzene | 1-Ethyl-4-isobutylbenzene is produced from the reductive deoxygenation of 4'-Isobutylacetophenone (I780065), a degradation product of Ibuprofen in tablets, which is a known toxin. Group: Biochemicals. Grades: Highly Purified. CAS No. 100319-40-2. Pack Sizes: 5mg, 25mg. Molecular Formula: C12H18, Molecular Weight: 162.27. US Biological Life Sciences. | Worldwide |
| 1-Hydroxybenz [a]anthracene | 1-Hydroxybenz [a]anthracene is a metabolite of monohydroxy polycyclic aromatic hydrocarbon (PAH) toxin. Group: Biochemicals. Grades: Highly Purified. CAS No. 69847-26-3. Pack Sizes: 1mg, 10mg. Molecular Formula: C18H12O, Molecular Weight: 244.29. US Biological Life Sciences. | Worldwide |
| 2-Phenylethyl isothiocyanate | 2-Phenylethyl isothiocyanate is a potent antifungal agent. 2-Phenylethyl isothiocyanate significantly inhibited spore germination and mycelial growth of Alternaria alternata , with a MIC (minimum inhibitory concentration) of 1.22 mM. The antifungal effect of 2-Phenylethyl isothiocyanate against Alternaria alternata might be via reduction in toxin content and breakdown of cell membrane integrity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2-PE ITC. CAS No. 2257-9-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-23155. |  |
| (2S,3S,4aR,6R,8aR)-2,3,4a,5,6,8a-Hexahydro-7-iodo-2,3-dimethoxy-2,3,6-trimethyl-1,4-benzodioxin-6-ol | (2S,3S,4aR,6R,8aR)-2,3,4a,5,6,8a-Hexahydro-7-iodo-2,3-dimethoxy-2,3,6-trimethyl-1,4-benzodioxin-6-ol is an intermediate in the synthesis of (-)-Altenuene (A575740), a toxin isolated from the fungus Alternaria tenuis. Group: Biochemicals. Grades: Highly Purified. CAS No. 888723-97-5. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| (2S,3S,4aR,6S,8aR)-2,3,4a,5,6,8a-Hexahydro-7-iodo-2,3-dimethoxy-2,3,6-trimethyl-1,4-benzodioxin-6-ol | (2S,3S,4aR,6S,8aR)-2,3,4a,5,6,8a-Hexahydro-7-iodo-2,3-dimethoxy-2,3,6-trimethyl-1,4-benzodioxin-6-ol is an intermediate in the synthesis of (-)-Altenuene (A575740), a toxin isolated from the fungus Alternaria tenuis. Group: Biochemicals. Grades: Highly Purified. CAS No. 888723-91-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| (2S,3S,4aR,6S,8R,8aR)-Octahydro-6,8-dihydroxy-2,3-dimethoxy-2,3-dimethyl-1,4-benzodioxin-6-carboxylic Acid Methyl Ester | (2S,3S,4aR,6S,8R,8aR)-Octahydro-6,8-dihydroxy-2,3-dimethoxy-2,3-dimethyl-1,4-benzodioxin-6-carboxylic Acid Methyl Ester is an intermediate in the synthesis of (-)-Altenuene (A575740), a toxin isolated from the fungus Alternaria tenuis. Group: Biochemicals. Alternative Names: [2S-(2α,3 β,4a β,6 β,8 β,8aα)]-Octahydro-6,8-dihydroxy-2,3-dimethoxy-2,3-dimethyl-1,4-benzodioxin-6-carboxylic Acid Methyl Ester. Grades: Highly Purified. CAS No. 176798-26-8. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| (2S,3S,4aR,8aR)-2,3,4a,8a-Tetrahydro-2,3-dimethoxy-2,3-dimethyl-1,4-benzodioxin-6(5H)-one | (2S,3S,4aR,8aR)-2,3,4a,8a-Tetrahydro-2,3-dimethoxy-2,3-dimethyl-1,4-benzodioxin-6(5H)-one is an intermediate in the synthesis of (-)-Altenuene (A575740), a toxin isolated from the fungus Alternaria tenuis. Group: Biochemicals. Grades: Highly Purified. CAS No. 286936-09-2. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| (2S,3S,4aR,8aR)-2,3,4a,8a-Tetrahydro-7-iodo-2,3-dimethoxy-2,3-dimethyl-1,4-benzodioxin-6(5H)-one | (2S,3S,4aR,8aR)-2,3,4a,8a-Tetrahydro-7-iodo-2,3-dimethoxy-2,3-dimethyl-1,4-benzodioxin-6(5H)-one is an intermediate in the synthesis of (-)-Altenuene (A575740), a toxin isolated from the fungus Alternaria tenuis. Group: Biochemicals. Grades: Highly Purified. CAS No. 334700-48-0. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| (2S,3S,4aR,8R,8aR)-Hexahydro-8-hydroxy-2,3-dimethoxy-2,3-dimethyl-1,4-benzodioxin-6(5H)-one | (2S,3S,4aR,8R,8aR)-Hexahydro-8-hydroxy-2,3-dimethoxy-2,3-dimethyl-1,4-benzodioxin-6(5H)-one is an intermediate in the synthesis of (-)-Altenuene (A575740), a toxin isolated from the fungus Alternaria tenuis. Group: Biochemicals. Grades: Highly Purified. CAS No. 286936-08-1. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| 3,5-Dimethoxyphenol | 3,5-Dimethoxyphenol is a toxin metabolite, found in human consuming yew leaves [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Phloroglucinol Dimethyl Ether. CAS No. 500-99-2. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g; 10 g. Product ID: HY-W001117. | |
| 3,8,9-Trihydroxy-7-(10-hydroxy-7,9-dimethoxy-1,3-dimethyl-3,4-dihydro-1H-benzo[g]isochromen-5-yl)-3-methyl-2,4-dihydroanthracen-1-one | 3,8,9-Trihydroxy-7-(10-hydroxy-7,9-dimethoxy-1,3-dimethyl-3,4-dihydro-1H-benzo[g]isochromen-5-yl)-3-methyl-2,4-dihydroanthracen-1-one. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Tullidinol, T-544 toxin, Toxin T 544, Karwinskia toxin T-544, NSC235814, AIDS071900, AIDS-071900, CID99832, T544, T 544, LS-20399, 1(2H)-Anthracenone, 3,4-dihydro-7-(3,4-dihydro-10-hydroxy-7,9-dimethoxy-1,3-dimethyl-1H-naphtho(2,3-c)pyran-5-yl)-3,8,9-trihydroxy-3-methyl-, 1(2H)-Anthracenone, 7-(3,4-dihydro-10-hydroxy-7,9-dimethoxy-1,3-dimethyl-1H-naphtho(2,3-c)pyran-5-yl)-3,4-dihydro-3,8,9-trihydroxy-3-methyl-, 56678-09-2, 3,8,9-Trihydroxy-7-(10-hydroxy-7,9-dimethoxy-1,3-dimethylbenzo[g]isochroman-5-yl)-3-methyl-2,3,4-trihydroanthracen-1-one. Product Category: Heterocyclic Organic Compound. CAS No. 56678-09-2. Molecular formula: C32H32O8. Mole weight: 544.592 g/mol. Purity: 0.96. IUPACName: 3,8,9-trihydroxy-7-(10-hydroxy-7,9-dimethoxy-1,3-dimethyl-3,4-dihydro-1H-benzo[g]isochromen-5-yl)-3-methyl-2,4-dihydroanthracen-1-one. Density: 1.351g/cm³. Product ID: ACM56678092. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 4-O-(α-D-Galactopyranosyl)-D-galactose | Defines the P blood-group system and it functions as specific ligands towards receptors of uropathogenic E. coli and the Shigella dysenteriae toxin. Uses: Defines the p blood-group system and it functions as specific ligands towards receptors of uropathogenic e. coli and the shigella dysenteriae toxin. Synonyms: Gal1-α-4Gal; 4-O-α-D-Galactopyranosyl-D-galactose; Galactose, 4-O-α-D-galactopyranosyl-, D-; 4α-Galactobiose; Galabiose; α-D-Galp-(1-4)-D-Gal. Grade: 97%. CAS No. 13117-26-5. Molecular formula: C12H22O11. Mole weight: 342.30. | |
| 5-Hydroxy-7-methoxy-2,2-dimethyl-4H-1,3-benzodioxin-4-one | 5-Hydroxy-7-methoxy-2,2-dimethyl-4H-1,3-benzodioxin-4-one is an intermediate for the synthesis of the precursor compound for Altenuene (A575740), a toxin isolated from the fungus Alternaria tenuis. Group: Biochemicals. Grades: Highly Purified. CAS No. 532394-23-3. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| 5-methylphenazine-1-carboxylate 1-monooxygenase | The enzyme, characterized from the bacterium Pseudomonas aeruginosa, is involved in the biosynthesis of pyocyanin, a toxin produced and secreted by the organism. It can also act on phenazine-1-carboxylate, converting it into phenazin-1-ol. Group: Enzymes. Synonyms: phzS (gene name). Enzyme Commission Number: EC 1.14.13.218. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0820; 5-methylphenazine-1-carboxylate 1-monooxygenase; EC 1.14.13.218; phzS (gene name). Cat No: EXWM-0820. | |
| 7-Methoxy-2,2-dimethyl-4H-1,3-benzodioxin-4-one | 7-Methoxy-2,2-dimethyl-4H-1,3-benzodioxin-4-one is used in the synthesis of the precursor compound for Altenuene (A575740), a toxin isolated from the fungus Alternaria tenuis. Group: Biochemicals. Grades: Highly Purified. CAS No. 888723-96-4. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| ABMA | ABMA is a broad-spectrum inhibitor of intracellular toxin and pathogens. It efficiently protects cells against various pathogens including viruses, intracellular bacteria, and parasite. ABMA selectively acts at host cell late endosomes rather than targeting toxin or pathogen itself. Synonyms: Adamantan-1-yl-(5-bromo-2-methoxy-benzyl)-amine; adamantanyl[(5-bromo-2-methoxyphenyl)methyl]amine. Grade: 99%. CAS No. 332108-65-3. Molecular formula: C18H24BrNO. Mole weight: 350.29. | |
| Acetyl coenzyme A sodium salt | Acetyl coenzyme A sodium salt, a pivotal molecule in the biomedical industry, is widely utilized in fatty acid and cholesterol biosynthesis, as well as the citric acid cycle. Its role in drug and toxin metabolism and breakdown in the body is also noteworthy. Besides, it contributes to treating metabolic disorders such as diabetes, obesity, and cancer. Its multifaceted functions make it a molecule of great scientific significance. Synonyms: Acetyl CoA. Grade: 90%. CAS No. 102029-73-2. Molecular formula: C23H38N7O17P3S·xNa. Mole weight: 809.57 (free acid). | |
| Acetyl hexapeptide-3 | Acetyl hexapeptide-3 is a synthetic peptide that mimics the N-terminal of SNAP-25 (a substrate of Botulinum toxin (Botox)) protein and consists of six amino acids. A cosmetic formulation acts as an anti-wrinkle ingredient used in anti-aging products. Synonyms: N-Acetyl-L-α-glutamyl-L-α-glutamyl-L-methionyl-L-glutaminyl-L-arginyl-L-argininamide; Acetyl hexapeptide 8; Argireline; Argireline NP. Grade: ≥98%. CAS No. 616204-22-9. Molecular formula: C34H60N14O12S. Mole weight: 888.99. | |
| Acetyl Hexapeptide-8 | Acetyl Hexapeptide-8 is an amino-peptide developed to help reduce the appearance of fine lines and wrinkles. Acetyl Hexapeptide-8 is also a peptide which is a fragment of SNAP-25, a substrate of Botulinum toxin (Botox). Acetyl Hexapeptide-8 cosmetics have become a popular application for wrinkle treatment in the USA and Europe. Categories: Acetyl Hexapeptide 8. |  United States and all of its trading partners.. |
| Actoxumab | Actoxumab (Anti-C. difficile Toxin A Recombinant Antibody) is a antitoxin antibody against C. difficile toxin A by neutralizing TcdA. Actoxumab prevents both the damage to the gut wall and the inflammatory response, which are associated with C. difficile. Actoxumab has synergy effect with Bezlotoxumab (HY-P9929) targeting TcdB [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-C. difficile Toxin A Recombinant Antibody. CAS No. 1245634-25-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99277. | |
| Actoxumab | Actoxumab is a human monoclonal antibody that binds to C. difficile toxin A and thus preventing toxin from binding to host cells. Actoxumab was developed in conjunction with bezlotoxumab for the treatment of Clostridioides difficile infection. Synonyms: MK-3415; MK 3415; MK3415; GS-CDA1; CDA1. Grade: 95%. CAS No. 1245634-25-6. Molecular formula: C6476H10000N1740O2010S45. Mole weight: 145.8 kDa. | |
| Adenosine A1 Receptor Agonist II, CCPA ( (2R, 3R, 4S, 5R) -2- (2-chloro-6- (cyclopentylamino) -9H-purin-9-yl) -5- (hydroxymethyl) tetrahydrofuran-3, 4-diol, 2-Chloro-N6-cyclopentyladenosine) | An adenosine analog that acts as a selective, high affinity agonist for Adenosine A1 receptor (A1R) (Ki = 800 pM; 2.3uM, 18.8uM, and 42nM for human A1, A2A, A2B, A3 respectively). Shown to be centrally active following systemic administration and exhibits anti-convulsive effects. Also reported to inhibit adenylate cyclase activity in rat fat cell membrane (IC50 = 33nM). Diminishes respiratory rhythm, reduces heart rate, and enhances the activity of KATP channels. Reduces norepinephrine release by about 50% in untreated and pertussis toxin treated hearts.CAS Number:37739-05-2. Group: Biochemicals. Grades: Highly Purified. CAS No. 37739-05-2. Pack Sizes: 10mg. Molecular Formula: C??H??ClN?O?. US Biological Life Sciences. | Worldwide |
| AK-toxin I | It is produced by the strain of Alternaria kikuchiana AS-1223. It's a plant toxin (especially for pear trees). Synonyms: CTK3E8898; (2E,4E,6E)-8-(2-acetamido-3-phenyl-butanoyl)oxy-8-(2-methyloxiran-2-yl)octa-2,4,6-trienoic Acid. Grade: 95%. CAS No. 85146-09-4. Molecular formula: C23H27NO6. Mole weight: 413.46. | |
| AK-toxin ll | It is produced by the strain of Alternaria kikuchiana AS-1223. It's a plant toxin (especially for pear trees). Synonyms: L-Phenylalanine, N-acetyl-, 7-carboxy-1-(2-methyloxiranyl)-2,4,6-heptatrienyl ester, (2S-(2R*(1S*,2E,4Z,6E)))-. Grade: 95%. CAS No. 85146-10-7. Molecular formula: C22H25NO6. Mole weight: 399.44. | |
| ALPHA-AMANITIN | α-Amanitin is produced by the strain of Amanita phalloides. It is highly toxic to humans and can cause salivation, vomiting, bleeding, diarrhea, cyanosis, muscle convulsions, spasms, and death. It is the principal toxin of several deadly poisonous mushrooms and exerts its toxic effects by inhibiting RNA polymerase II. Synonyms: α-Amatoxin; cyclo[L-Asparaginyl-4-hydroxy-L-proly-(R-4,5-dihydroxy-L-isoleucyl-6-hydroxy-2-mercapto-L-tryptophylglycyl-L-isoleucylglycyl-L-cysteinyl]cyclic (4-8)-sulfide (R)-S-oxide. Grade: ≥98%. CAS No. 23109-05-9. Molecular formula: C39H54N10O14S. Mole weight: 918.97. | |
| Altenuene | (-)-Altenuene is a toxin isolated from the fungus Alternaria tenuis. It has antioxidant activity and inhibits cholinesterases. Synonyms: (2R,3R,4aR)-2,3,4,4a-Tetrahydro-2,3,7-trihydroxy-9-methoxy-4a-methyl-6H-dibenzo[b,d]pyran-6-one. Grade: >95%. CAS No. 29752-43-0. Molecular formula: C15H16O6. Mole weight: 292.29. | |
| anthrax lethal factor endopeptidase | From the bacterium Bacilus anthracis that causes anthrax. One of three proteins that are collectively termed anthrax toxin. Cleaves several MAP kinase kinases near their N-termini, preventing them from phosphorylating the downstream mitogen-activated protein kinases. In peptidase family M34. Group: Enzymes. Synonyms: lethal toxin. Enzyme Commission Number: EC 3.4.24.83. CAS No. 477950-41-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4367; anthrax lethal factor endopeptidase; EC 3.4.24.83; 477950-41-7; lethal toxin. Cat No: EXWM-4367. | |
| atrolysin A | A hemorrhagic endopeptidase of 68 kDa, one of six hemorrhagic toxins in the venom of western diamondback rattlesnake. The 60 kDa hemorrhagic toxin 1 of Crotalus ruber ruber shows identical specificity. In peptidase family M12 (astacin family). Related metalloendopeptidases from rattlesnake venoms are EC 3.4.24.41 (atrolysin B), EC 3.4.24.42 (atrolysin C), EC 3.4.24.43 (atroxase), EC 3.4.24.44 (atrolysin E), EC 3.4.24.45 (atrolysin F), EC 3.4.24.46 (adamalysin), EC 3.4.24.47 (horrilysin), and EC 3.4.24.48 (ruberlysin). Group: Enzymes. Synonyms: Crotalus atrox metalloendopeptidase a; hemorrhagic toxin a; Crotalus atrox α-proteinase; Crotalus atrox proteinase; bothropasin. Enzyme Commission Number: EC 3.4.24.1. CAS No. 37288-82-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4291; atrolysin A; EC 3.4.24.1; 37288-82-7; Crotalus atrox metalloendopeptidase a; hemorrhagic toxin a; Crotalus atrox α-proteinase; Crotalus atrox proteinase; bothropasin. Cat No: EXWM-4291. | |
| atrolysin B | From the venom of the western diamondback rattlesnake (Crotalus atrox). In peptidase family M12 (astacin family). Group: Enzymes. Synonyms: Crotalus atrox metalloendopeptidase b; hemorrhagic toxin b; Ht-b. Enzyme Commission Number: EC 3.4.24.41. CAS No. 172306-48-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4323; atrolysin B; EC 3.4.24.41; 172306-48-8; Crotalus atrox metalloendopeptidase b; hemorrhagic toxin b; Ht-b. Cat No: EXWM-4323. | |
| atrolysin C | A 24 kDa hemorrhagic endopeptidase from the venom of the western diamondback rattlesnake (Crotalus atrox) that digests type IV collagen, and exists as two forms, c and d. Phosphoramidon inhibits in the 0.1 mM range. In peptidase family M12 (astacin family). Hemorrhagic toxin-2 of C. ruber ruber has the same Mr and specificity and is a homologue. Group: Enzymes. Synonyms: Crotalus atrox metalloendopeptidase c; hemorrhagic toxin c and d. Enzyme Commission Number: EC 3.4.24.42. CAS No. 158886-17-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4324; atrolysin C; EC 3.4.24.42; 158886-17-0; Crotalus atrox metalloendopeptidase c; hemorrhagic toxin c and d. Cat No: EXWM-4324. | |
| atrolysin E | A 25.7 kDa hemorrhagic endopeptidase from the venom of the western diamondback rattlesnake (Crotalus atrox) that digests basement membrane components, including the triple helix of type IV collagen. Such action is believed to contribute to the hemorrhagic property by weakening capillary walls. In peptidase family M12 (astacin family). Group: Enzymes. Synonyms: Crotalus atrox metalloendopeptidase e; hemorrhagic toxin e. Enzyme Commission Number: EC 3.4.24.44. CAS No. 172306-51-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4326; atrolysin E; EC 3.4.24.44; 172306-51-3; Crotalus atrox metalloendopeptidase e; hemorrhagic toxin e. Cat No: EXWM-4326. | |
| atrolysin F | A 64 kDa hemorrhagic endopeptidase from the venom of the western diamondback rattlesnake (Crotalus atrox) that digests the γ chain of fibrinogen. Immunologically distinct from EC 3.4.24.1, atrolysin A. Group: Enzymes. Synonyms: Crotalus atrox metalloendopeptidase; hemorrhagic toxin f; Crotalus atrox metalloendopeptidase f. Enzyme Commission Number: EC 3.4.24.45. CAS No. 172306-52-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4327; atrolysin F; EC 3.4.24.45; 172306-52-4; Crotalus atrox metalloendopeptidase; hemorrhagic toxin f; Crotalus atrox metalloendopeptidase f. Cat No: EXWM-4327. | |
| β-Amanitin | β-Amanitin is a cyclic peptide toxin in the poisonous Amanita phalloides mushroom. β-Amanitin inhibits inhibits eukaryotic RNA polymerase II and III. β-Amanitin inhibits protein synthesis. β-Amanitin can be used as a cytotoxic component of antibody-drug conjugates (ADCs) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 21150-22-1. Pack Sizes: 100 μg; 500 μg; 1 mg. Product ID: HY-125586. | |
| β-cyclopiazonate dehydrogenase | A flavoprotein (FAD). Cytochrome c and various dyes can act as acceptor. Cyclopiazonate is a microbial toxin. Group: Enzymes. Synonyms: β-cyclopiazonate oxidocyclase; β-cyclopiazonic oxidocyclase; β-cyclopiazonate:(acceptor) oxidoreductase (cyclizing). Enzyme Commission Number: EC 1.21.99.1. CAS No. 9059-00-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1262; β-cyclopiazonate dehydrogenase; EC 1.21.99.1; 9059-00-1; β-cyclopiazonate oxidocyclase; β-cyclopiazonic oxidocyclase; β-cyclopiazonate:(acceptor) oxidoreductase (cyclizing). Cat No: EXWM-1262. | |
| Biliatresone | Biliatresone is a natural toxin isolated from Dysphania glomulifera and D. littoralis. Biliatresone, a 1,2-diaryl-2-propenone class of isoflavonoid, produces extrahepatic biliary atresia in a zebrafish model [1]. Uses: Scientific research. Group: Natural products. CAS No. 1801433-90-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119412. | |
| Black rice powder | Black rice powder. Applications: Black rice and other whole grain rice varieties- like wild, red, or brown rices- have a similar amount of fiber, with about 2-3 grams per half cup serving. the fiber in black rice helps to prevent constipation, bloating, and other unwanted digestive symptoms. fiber binds to waste and toxins within the digestive tract, helping to pull them out and to contribute to regular bowel function. Group: Others. Purity: 100% black rice. Appearance: This product is grey powder with natural smell and best taste. Source: Black rice is a range of rice types of the species Oryza sativa L., some of which are glutinous rice. Varieties include Indonesian black rice and Thai jasmine black rice. Black rice has a deep black color and usually turns deep purple when cooked. Its dark purple color is primarily due to its anthocyanin content, which is higher by weight than that of other colored grains. Black rice powder; longevity rice; purple rice. Cat No: EXTC-206. | |
| Bongkrekic acid | Bongkrekic acid is an acid-labile toxin produced by Pseudomonas cocoveneans. Uses: Anti-bacterial agents. Synonyms: (2E,4Z,6R,8Z,10E,14E,17S,18E,20Z)-20-(Carboxymethyl)-6-methoxy-2,5,17-trimethyl-2,4,8,10,14,18,20-docosaheptaenedioic Acid; (-)-Bongkrekic Acid; BA; Flavotoxin A. Grade: ≥98%. CAS No. 11076-19-0. Molecular formula: C28H38O7. Mole weight: 486.60. | |
| BPIPP | BPIPP is a non-competitive guanylyl cyclase (GC) and adenylyl cyclase (AC) inhibitor. It downregulates cAMP and cGMP synthesis, suppresses cGMP accumulation in a variety of cell lines (IC50 = 3.4 - 11.2 μM), inhibits GC-stimulated Cl- transport in vitro, and suppresses toxin-induced intestinal fluid accumulation in vivo. BPIPP may be a useful treatment of diarrhea. Uses: Potential treatment of diarrhea. Synonyms: 5-(3-Bromophenyl)-5,11-dihydro-1,3-dimethyl-1H-indeno[2',1':5,6]pyrido[2,3-d]pyrimidine-2,4,6(3H)-trione. Grade: ≥99% by HPLC. CAS No. 325746-94-9. Molecular formula: C22H16BrN3O3. Mole weight: 450.28. | |
| bursehernin 5'-monooxygenase | This cytochrome P450 enzyme, characterized from the plant Sinopodophyllum hexandrum, is involved in the biosynthetic pathway of podophyllotoxin, a non-alkaloid toxin lignan whose derivatives are important anticancer drugs. Group: Enzymes. Synonyms: CYP71CU1 (gene name); bursehernin 5'-hydroxylase. Enzyme Commission Number: EC 1.14.13.213. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0815; bursehernin 5'-monooxygenase; EC 1.14.13.213; CYP71CU1 (gene name); bursehernin 5'-hydroxylase. Cat No: EXWM-0815. | |
| Candidalysin | Candidalysin is a cytolytic peptide toxin, which is initially isolated from Candida albicans and exhibits virulent and avirulent characters. Candidalysin activates epithelial cell signaling pathways by interacting with the epithelial growth factor receptor (EGFR) of host cells, activates matrix metalloproteinase ( MMP ) and calcium flux, resulting in inflammatory responses and recruitment of immune cells. Candidalysin exhibits cytotoxicity by dealing membran damage to host cells [1]. Uses: Scientific research. Group: Peptides. CAS No. 1906866-53-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10408. | |
| (+)-CBI-CDPI1 | (+)-CBI-CDPI1 is an enhanced functional analog of CC-1065. It is also a DNA alkylating agent that acts as an antibody drug conjugate (ADC) toxin. Synonyms: Benzo[1,2-b:4,3-b']dipyrrole-3(2H)-carboxamide, 7-[[(8bR,9aS)-9,9a-dihydro-4-oxo-1H-benzo[e]cycloprop[c]indol-2(4H)-yl]carbonyl]-1,6-dihydro-; 7-{[(1aS,9bR)-5-Oxo-1a,2-dihydro-1H-benzo[e]cyclopropa[c]indol-3(5H)-yl]carbonyl}-1,6-dihydropyrrolo[3,2-e]indole-3(2H)-carboxamide. Grade: ≥95%. CAS No. 128300-14-1. Molecular formula: C25H20N4O3. Mole weight: 424.45. | |
| (+)-CBI-CDPI2 | (+)-CBI-CDPI2 is an enhanced functional analog of CC-1065. It is also a DNA alkylating agent that acts as an antibody drug conjugate (ADC) toxin. Synonyms: Benzo[1,2-b:4,3-b']dipyrrole-3(2H)-carboxamide, 7-[[7-[[(1aS,9bR)-1a,2-dihydro-5-oxo-1H-benzo[e]cycloprop[c]indol-3(5H)-yl]carbonyl]-1,6-dihydrobenzo[1,2-b:4,3-b']dipyrrol-3(2H)-yl]carbonyl]-1,6-dihydro-; 7-{[7-{[(1aS,9bR)-5-Oxo-1a,2-dihydro-1H-benzo[e]cyclopropa[c]indol-3(5H)-yl]carbonyl}-1,6-dihydropyrrolo[3,2-e]indol-3(2H)-yl]carbonyl}-1,6-dihydropyrrolo[3,2-e]indole-3(2H)-carboxamide. Grade: 95%. CAS No. 128300-15-2. Molecular formula: C36H28N6O4. Mole weight: 608.65. | |
| CFTR Inhibitor-172 (CFTRinh-172, 3-[ (3-Trifluoromethyl) phenyl]-5-[ (4-carboxyphenyl) methylene]-2-thioxo-4-thiazolidinone) | A cell-permeable 2-thio-4-thiazolidinone compound that acts as a potent, reversible, rapid, and voltage-independent inhibitor of CFTR (cystic fibrosis transmembrane conductance regulator)-mediated Cl- transport in human airway cells (Ki ~300nM). It does not prevent elevation of cellular cAMP, nor does it inhibit non-CFTR Cl- channels, MDR-1, ATP-sensitive K+ channels, or a series of other transporters even at concentrations as high as 5uM. Shown to block cholera toxin-induced intestinal fluid secretion in mice. May be also useful for reducing intestinal fluid loss in other secretory diarrheas. Group: Biochemicals. Grades: Highly Purified. CAS No. 307510-92-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Clindamycin | Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin can inhibit bacterial protein synthesis, possessing the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla). Clindamycin also can be used for researching malaria. Uses: Designed for use in research and industrial production. Additional or Alternative Names: L-threo-alpha-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(((1-methyl-4-propyl-2-pyrrolidinyl)carbonyl)amino)-1-thio-, (2S-trans)-. Product Category: Inhibitors. CAS No. 18323-44-9. Molecular formula: C18H33ClN2O5S. Mole weight: 424.98. Product ID: ACM18323449. Alfa Chemistry ISO 9001:2015 Certified. | |
| Curvularin | It is produced by the strain of Curvularia sp., Penicillum gilmanii and Pen. citroviride. It strongly inhibits cell division and is a toxin harmful to plants. Synonyms: S-Curvularin; NSC 166071; 11,13-Dihydroxy-4-methyl-4,5,6,7,8,9-hexahydro-2H-3-benzoxacyclododecine-2,10(1H)-dione; 2H-3-Benzoxacyclododecin-2,4,5,6,7,8,9-hexahydro-11,13-dihydroxy-4-methyl-, (S)-. Grade: >99% by HPLC. CAS No. 10140-70-2. Molecular formula: C16H20O5. Mole weight: 292.33. | |
| Cylindrospermopsin | It is produced by the strain of Cylindrospermopsis raciborskii. Cylindrospermopsin is a tricyclic uracil derivative which is a cyanobacterial toxin. And it targets protein and glutathione synthesis in hepatocytes (IC50s = 1.3 and 2.4 μM, respectively), leading to cell death. It has been proved to inhibit the activity of the uridine monophosphate synthase complex with a Ki value of 10 μM. Synonyms: [2aS-[2aα,3α,4α,5aα,7β(S*)]]-6-[Hydroxy[2,2a,3,4,5,5a,6,7-octahydro-3-methyl-4-(sulfooxy)-1H-1,8,8b-triazaacenaphthylen-7-yl]methyl]-2,4(1H,3H)-pyrimidinedione; 6-[(R)-Hydroxy[(2aS,3R,4S,5aS,7R)-2,2a,3,4,5,5a,6,7-octahydro-3-methyl-4-(sulfooxy)-1H-1,8,8b-triazaacenaphthylen-7-yl]methyl]-2,4(1H,3H)-pyrimidinedione; Cylindrospermopsine. Grade: ≥95%. CAS No. 143545-90-8. Molecular formula: C15H21N5O7S. Mole weight: 415.43. | |
| (Dap22)-ShK | (Dap22)-ShK (ShK Dap22) peptide is a synthetic derivative of the well-known ShK toxin isolated from the venom of the Carribean sea anemone Stoichactis helianthus. ShK-Dap22 is an extremely potent KV1.3 channel blocker (Kd = 23 pM for mKV1.3 currents). Synonyms: (DAP22)-SHK; ShK-Dap22. Grade: > 97%. CAS No. 220384-25-8. Molecular formula: C166H268N54O48S7. Mole weight: 4012.8. | |
| Denileukin diftitox | Denileukin diftitox is a recombinant IL - 2-diphtheria toxin conjugate. It works by interfering with the growth of cancer cells, which results in the death of the cells. Synonyms: DAB(389)-interleukin-2/DAB389 interleukin-2/DAB389/interleukin-2 immunotoxin/DABIL2. CAS No. 173146-27-5. Molecular formula: C2560H4042N678O799S17. Mole weight: 57640.606. | |
| (-)-deoxypodophyllotoxin synthase | The enzyme, characterized from the plant Sinopodophyllum hexandrum, is involved in the biosynthetic pathway of podophyllotoxin, a non-alkaloid toxin lignan whose derivatives are important anticancer drugs. It catalyses the closure of the central six-membered ring in the aryltetralin scaffold. Group: Enzymes. Synonyms: 2-ODD (gene name). Enzyme Commission Number: EC 1.14.11.50. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0669; (-)-deoxypodophyllotoxin synthase; EC 1.14.11.50; 2-ODD (gene name). Cat No: EXWM-0669. | |
| DGN462 | DGN462 is a potent DNA alkylating agent with antitumor activity, such as against acute myeloid leukemia (AML). DGN462 can be used as an ADC toxin molecule to synthesize ADC. Synonyms: DGN-462; IMGN-779; IMGN779-linker; (5aS)-10-Methoxy-9-({3-[{2-[2-(2-methoxyethoxy)ethoxy]ethyl}(2-methyl-2-sulfanylpropyl)amino]-5-({[(5aS)-10-methoxy-12-oxo-5a,6,7,12-tetrahydro-5H-indolo[2,1-c][1,4]benzodiazepin-9-yl]oxy}methyl)benzyl}oxy)-5,5a-dihydro-12H-indolo[2,1-c][1,4]benzodiazepin-12-one; 6H-Indolo[2,1-c][1,4]benzodiazepin-6-one, 9-[[3-[[[(12aS)-12a,13-dihydro-8-methoxy-6-oxo-6H-indolo[2,1-c][1,4]benzodiazepin-9-yl]oxy]methyl]-5-[(2-mercapto-2-methylpropyl)[2-[2-(2-methoxyethoxy)ethoxy]ethyl]amino]phenyl]methoxy]-11,12,12a,13-tetrahydro-8-methoxy-, (12aS)-; (12aS)-9-[[3-[[[(12aS)-12a,13-Dihydro-8-methoxy-6-oxo-6H-indolo[2,1-c][1,4]benzodiazepin-9-yl]oxy]methyl]-5-[(2-mercapto-2-methylpropyl)[2-[2-(2-methoxyethoxy)ethoxy]ethyl]amino]phenyl]methoxy]-11,12,12a,13-tetrahydro-8-methoxy-6H-indolo[2,1-c][1,4]benzodiazepin-6-one. Grade: ≥95%. CAS No. 1394079-41-4. Molecular formula: C53H59N5O9S. Mole weight: 942.13. | |
| Diethyl D-(-)-Tartrate | Diethyl D-(-)-Tartrate is used as a chiral reagent in a host of chemical reactions, suhc as marin toxin and antitumor agent phorboxazole A, or asymmetric syntheses of S,S-dialkyl-substituted sulfoximines. Group: Biochemicals. Alternative Names: Diethyl D-tartrate; [S-(R*,R*)]-2,3-Dihydroxybutanedioic Acid Diethyl Ester; (-)-Tartaric Acid Diethyl Ester; (-)-Diethyl Tartrate; (2S,3S)-Diethyl Tartrate; (S,S)-Diethyl Tartrate; D-(-)-Diethyl Tartrate; D-Diethyl Tartarate; D-Ethyl Tartrate; D-Tartaric Acid Diethyl Ester; Diethyl (-)-D-Tartrate; Diethyl (2S,3S)-(-)-Tartrate; Diethyl (S,S)-(-)-Tartrate. Grades: Highly Purified. CAS No. 13811-71-7. Pack Sizes: 10g. US Biological Life Sciences. | Worldwide |
| Dihydroxyaflavinine | Dihydroxyaflavinine is a metabolite of Aspergillus flavus and is a fungal toxin. It inhibits non-competitively GABAA receptor channel expressed in Xenopus oocytes. It displays oral toxicity to the corn earworm (Heliothis zea) and fall armyworm (Spodoptera frugiperda). Synonyms: 20,25-Dihydroxyaflavinine; 1H-Benzo[d]naphthalene-1,5-diol, 2,3,4,4a,5,6,7,7a,10,11-decahydro-9-[(1R)-2-hydroxy-1-methylethyl]-8-(1H-indol-3-yl)-4,4a,7-trimethyl-, (1R,4S,4aR,5S,7S,7aR,11aR)-rel-; 1H-Benzo(d)naphthalene-1,5-diol, 2,3,4,4a,5,6,7,7a,10,11-decahydro-9-(2-hydroxy-1-methylethyl)-8-(1H-indol-3-yl)-4,4a,7-trimethyl-, (1alpha,4alpha,4aalpha,5beta,7alpha,7abeta,9(R*),11aR*)-. Grade: 98.0%. CAS No. 76410-56-5. Molecular formula: C28H39NO3. Mole weight: 437.61. | |
| diphthine-ammonia ligase | This amidase catalyses the last step in the conversion of an L-histidine residue in the translation elongation factor EF2 to diphthamide. This factor is found in all archaebacteria and eukaryotes, but not in eubacteria, and is the target of bacterial toxins such as the diphtheria toxin and the Pseudomonas exotoxin A (see EC 2.4.2.36, NAD+-diphthamide ADP-ribosyltransferase). The substrate of the enzyme, diphthine, is produced by EC 2.1.1.98, diphthine synthase. Group: Enzymes. Synonyms: diphthamide synthase; diphthamide synthetase; DPH6 (gene name); ATPBD4 (gene name); diphthine:ammonia ligase (AMP-forming). Enzyme Commission Number: EC 6.3.1.14. CAS No. 114514-33-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5717; diphthine-ammonia ligase; EC 6.3.1.14; 114514-33-9; diphthamide synthase; diphthamide synthetase; DPH6 (gene name); ATPBD4 (gene name); diphthine:ammonia ligase (AMP-forming). Cat No: EXWM-5717. | |
| Direct Blue 218 | Direct Blue 218 is an azo dye used in diagnostic imaging. Used in the prediction of rat carcinogenisis. Also used in textile dyes contributing to textile effluents and wastewaters. Environmental toxin on US EPA Toxic Release Inventory list (TRI) list. Group: Biochemicals. Alternative Names: [Tetrahydrogen -3, 3'- [ (3, 3'-dihydroxy-4, 4'-biphenylylene ) bis (azo) ] bis [5-amino-4-hydroxy-2, 7-naphthalene disulfonato] (4-) ] di-Copper Tetrasodium Salt; [ μ - [ [3, 3'- [ (3, 3'-Dihydroxy [1, 1'-biphenyl] -4, 4'-diyl) bis (azo) ] bis [5-amino-4-hydroxy-2, 7-naphthalene disulfonato] ] (8-) ] ] di-Cuprate (4-) Tetra sodium ; [ μ - [ [3, 3'- [ [3, 3'-Di (hydroxy- κ O) [1, 1'-biphenyl] -4, 4'-diyl] bis (azo- κ N1) ] bis [5-amino-4- (hydroxy- κ O) -2, 7-naphthalene disulfonato] ] (8-) ] ] di-Cuprate (4-) Tetrasodium;3,3'-[(3,3'-Dihydroxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[5-amino-4-hydroxy-2,7-Naphthalenedisulfonic Acid Copper Complex; Amanil Supra Blue 9GL; C.I. 24401; Carta Blue VP; Direct Blue 218; Fastusol Blue 9GLP; Intralite Blue 8GLL; Pontamine Bond Blue B; Pontamine Fast Blue 7GLN. Grades: Purified. CAS No. 28407-37-6. Pack Sizes: 1g, 5g, 10g. Molecular Formula: C??H??Cu?N?Na?O??S?, Molecular Weight: 1087.81. US Biological Life Sciences. | Worldwide |
| Duocarmycin DM free base | Duocarmycin DM free base, a DNA minor-groove alkylator, is an antibody agent conjugates (ADCs) toxin. Duocarmycin DM free base is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1116745-06-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128915. | |
| Duocarmycin DM free base | Duocarmycin DM free base is a DNA minor-groove alkylating agent, which can be used as an antibody drug conjugate (ADC) toxin. Duocarmycin DM free base is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity. Synonyms: [(1S)-1-(Chloromethyl)-5-hydroxy-1,2-dihydro-3H-benzo[e]indol-3-yl]{5-[2-(dimethylamino)ethoxy]-1H-indol-2-yl}methanone; Methanone, [(1S)-1-(chloromethyl)-1,2-dihydro-5-hydroxy-3H-benz[e]indol-3-yl][5-[2-(dimethylamino)ethoxy]-1H-indol-2-yl]-. Grade: ≥97%. CAS No. 1116745-06-2. Molecular formula: C26H26ClN3O3. Mole weight: 463.96. | |
| Duocarmycin MB | Duocarmycin MB is an antibody drug conjugate (ADC) toxin that can be used against multidrug resistant cell lines. Duocarmycin is a DNA alkylating agent that binds in minor groove. Synonyms: Carbamic acid, N-[2-[[(1S)-1-(chloromethyl)-1,2-dihydro-5-hydroxy-3H-benz[e]indol-3-yl]carbonyl]-1H-indol-6-yl]-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl N-[2-[[(1S)-1-(chloromethyl)-1,2-dihydro-5-hydroxy-3H-benz[e]indol-3-yl]carbonyl]-1H-indol-6-yl]carbamate; 2-Methyl-2-propanyl (2-{[(1S)-1-(chloromethyl)-5-hydroxy-1,2-dihydro-3H-benzo[e]indol-3-yl]carbonyl}-1H-indol-6-yl)carbamate. Grade: ≥95%. CAS No. 1613286-58-0. Molecular formula: C27H26ClN3O4. Mole weight: 491.97. | |
| Enfortumab vedotin-ejfv | Enfortumab vedotin-ejfv is a first-in-class monoclonal antibody drug conjugate that binds Nectin-4, a protein expressed on bladder cancer cells, and delivers the tubulin toxin, monomethyl auristatin E, into the cell causing cell death. Enfortumab vedotin-ejfv was approved by FDA for the treatment of locally advanced or metastatic urothelial cancer. Synonyms: Padcev. CAS No. 1346452-25-2. | |
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