Tacrine Suppliers USA
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Product | Description | |
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Tacrine Quick inquiry Where to buy Suppliers range | Tacrine is a centrally acting anticholinesterase and indirect cholinergic agonist for the palliative treatment of mild to moderate dementia of the Alzheimer's type. Uses: A centrally acting anticholinesterase and indirect cholinergic agonist. Synonyms: CS 12602, CS 12602, CS 12602; 1,2,3,4-Tetrahydro-5-aminoacridine; 1,2,3,4-tetrahydro-9-acridinamin; 1,2,3,4-tetrahydro-9-amino-acridin; 1,2,3,4-Tetrahydro-9-aminoacridine; 5-Amino-6,7,8,9-tetrahydroacridine; Acridine, 1,2,3,4-tetrahydro-9-amino-; Acridine, 9-amino-1,2,3,4-tetrahydro-. Grades: ≥95%. CAS No. 321-64-2. Molecular formula: C13H14N2. Mole weight: 198.27. | |
Tacrine Quick inquiry Where to buy Suppliers range | Tacrine, 321-64-2, 1,2,3,4-tetrahydroacridin-9-amine, Tetrahydroaminacrine, 1,2,3,4-TETRAHYDRO-9-ACRIDINAMINE, Tetrahydroaminoacridine, Tetrahydroaminocrine, Tetrahydroaminocrin, Cognex, 9-amino-1,2,3,4-tetrahydroacridine, Tacrinum, 9-Acridinamine, 1,2,3,4-tetrahydro-, CS 12602, Tacrina, Tacrinal, Tacrine [INN:BAN], Tacrinum [INN-Latin], Tacrina [INN-Spanish], 1,2,3,4-Tetrahydro-9-aminoacridine, Tacrinal (TN), Tacrine (INN), Acridine, 1,2,3,4-tetrahydro-9-amino-, 1,2,3,4-Tetrahydroaminoacridine, CHEMBL95, EINECS 206-291-2, 5-Amino-6,7,8,9-tetrahydroacridine (European), 5-Amino-6,7,8,9-tetrahydroacridine, BRN 0147610, UNII-4VX7YNB537, 1,2,3,4-Tetrahydro-acridin-9-ylamine, 4VX7YNB537, DTXSID1037272, CHEBI:45980, C13H14N2, 5,6,7,8-tetrahydroacridin-9-amine, MFCD00046923, 1,2,3,4-Tetrahydro-9-acridineamine, tacrine.HCl, NCGC00015054-06, TACRINE [INN], Cognex (TN), DTXCID9017272, 1,2,3,4-TETRAHYDRO-9-ACRIDINAMINE (SEE ALSO 1684-40-8), CAS-321-64-2, Tracine, 9-AMINOTETRAHYDROACRIDINE, 1acj, 2aow, 2aox, Romotal (Salt/Mix), Spectrum_000416, Tocris-0965, 1mx1, TACRINE [VANDF], TACRINE [MI], Prestwick0_000329, Prestwick1_000329, Prestwick2_000329, Prestwick3_000329, Spectrum2_001812, Spectrum3_001709, Spectrum4_000819, Spectrum5_001402, Lopac-A-3773, TACRINE [WHO-DD], D0E6YQ, cid_1935, SCHEMBL2828, 9-THA, NCIOpen2_003667, Lopac0_000036, Oprea1_008681, Acridine, 9-aminotetrahydro-, BSPBio_000337, BSPBio_003298, KBioGR_001337, KBioSS_000896, BIDD:GT0090, DivK1c_000936, SPBio_001823, SPBio_002258, BDBM8961, BPBio1_000371, GTPL6687, KBio1_000936, KBio2_000896, KBio2_003464, KBio2_006032, KBio3_002518, NINDS_000936, HMS2089F19, HMS3743C11, BCP03564, Tox21_110073, Tox21_302277, BBL001044, PDSP1_000330, PDSP2_000328, STK101308, AKOS000277493, Tox21_110073_1, AB89727, BCP9000019, CCG-204132, CS-O-02538, DB00382, LS-1191, SDCCGSBI-0050025.P004, 1,2,3,4-tetra -hydro-9-acridinamine, IDI1_000936, NCGC00015054-01, NCGC00015054-02, NCGC00015054-03, NCGC00015054-04, NCGC00015054-05, NCGC00015054-07, NCGC00015054-08, NCGC00015054-09, NCGC00015054-10, NCGC00015054-12, NCGC00024908-01, NCGC00024908-03, NCGC00024908-04, NCGC00024908-05, NCGC00255540-01, 1,2,3,4-tetrahydro-acridin-9-yl-amine, BS-28027, SY138494, Acridine, 9-amino-1,2,3,4-tetrahydro-, SBI-0050025.P003, HY-111338, 9-amino-1, | |
Tacrine hydrochloride Quick inquiry Where to buy Suppliers range | Tacrine hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1684-40-8. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
Tacrine hydrochloride Quick inquiry Where to buy Suppliers range | Tacrine hydrochloride is a potent cholinesterase inhibitor used for the treatment of memory deficits in patients with Alzheimers's disease. Tacrine hydrochloride has been shown to inhibit acetylcholinesterase (AChE) and butyrylcholinesterase (IC50s = 31 and 26.5 nM, respectively). Tacrine also inhibits the uptake of serotonin and norepinephrine in rat cerebral cortex and reduces depolarization-induced calcium influx through L-type calcium channels in SN56 neuronal cells. Uses: The treatment of alzheimers's disease. Synonyms: 1,2,3,4-Tetrahydro-5-aminoacridine hydrochloride; Tacrine HCl; Hydroaminacrine; NSC72108; NSC-72108; NSC72108; Tenakrin. Grades: ≥99% by HPLC. CAS No. 1684-40-8. Molecular formula: C13H14N2.HCl. Mole weight: 234.73. | |
Tacrine Hydrochloride Quick inquiry Where to buy Suppliers range | Tacrine Hydrochloride. Uses: For analytical and research use. Group: API Standards; Pharmaceutical Toxicology. Alternative Names: 9-Acridinamine, 1,2,3,4-tetrahydro-, monohydrochloride (9CI), Romotal,9-Acridinamine, 1,2,3,4-tetrahydro-, hydrochloride (1:1), Hydroaminacrine, CI 970, 9-Amino-1,2,3,4-Tetrahydroacridine hydrochloride, THA, Tenakrin, Acridine, 9-amino-1,2,3,4-tetrahydro-, monohydrochloride (8CI), Acridine, 9-amino-1,2,3,4-tetrahydro-, hydrochloride (7CI), Cognex, Tacrin hydrochloride, 5,6,7,8-Tetrahydroacridin-9-amine hydrochloride, 1,2,3,4-Tetrahydro-9-aminoacridine hydrochloride, Tacrine hydrochloride. CAS No. 1684-40-8. IUPAC Name: 1,2,3,4-tetrahydroacridin-9-amine;hydrochloride. Molecular formula: C13H14N2.ClH. Mole weight: 234.72. Catalog: APS1684408. SMILES: Cl.Nc1c2CCCCc2nc3ccccc13. Format: Neat. Product Type: API. Shipping: Room Temperature. | |
Tacrine hydrochloride hydrate Quick inquiry Where to buy Suppliers range | Tacrine is a centerally active acetylcholinesterase inhibitor. It has been approved for the treatment of Alzheimer's disease and other central nervous system disorders. Synonyms: Tacrine hydrochloride monohydrate. CAS No. 206658-92-6. Molecular formula: C13H14N2·xHCl·xH2O. Mole weight: 198.26. | |
1-Hydroxy Tacrine Quick inquiry Where to buy Suppliers range | One of the impurities of Tacrine, which is an effective cholinesterase inhibitor and could probably be active in studies of Alzheimers's disease. Uses: Cholinesterase inhibitors. Synonyms: 1-Hydroxy Tacrine. Grades: > 95%. CAS No. 124027-47-0. Molecular formula: C13H14N2O. Mole weight: 214.27. | |
1-Hydroxy Tacrine Maleate Quick inquiry Where to buy Suppliers range | One of the impurities of Tacrine, which is an effective cholinesterase inhibitor and could probably be active in studies of Alzheimers's disease. Uses: Cholinesterase inhibitors. Synonyms: 1-Hydroxy Tacrine Maleate; 9-Amino-1,2,3,4-tetrahydroacridin-1-ol Maleate; 9-Amino-1,2,3,4-tetrahydro-1-acridinol (2Z)-2-Butenedioate; HP 029; Mentane; P 83-6029A; Velnacrine Hydrogen Maleate; Velnacrine Maleate. Grades: > 95%. CAS No. 118909-22-1. Molecular formula: C13H14N2O. C4H4O4. Mole weight: 330.33. | |
bis(7)-Tacrine Quick inquiry Where to buy Suppliers range | Acetylcholinesterase (AChE) is the primary cholinesterase in the body. It is an enzyme catalyzing the breakdown of acetylcholine and some other choline esters that function as neurotransmitters. Tacrine is an amino acridine compound that inhibits acetylcholinesterase (AChE), which has been proposed as a clinical treatment for Alzheimer's disease. Bis(7)-Tacrine is a tacrine dimer, linked via a 7-carbon alkyl spacer. It inhibits AChE with an IC50 of 0.40 nM, making it more than 1,000 times more potent than tacrine. It is thought to have multiple mechanisms of action including inhibition of AChE, and inihbititon of the amyloid precursor protein/beta-amyloid cascade. It has been shown to inhibit the formation of Aβ1-42 oligomers and reduce the amount of pre-formed Aβ1-42 oligomers. Synonyms: 1,7-N-heptylene-bis-9,9'-amino-1,2,3,4-tetrahydro-acridine. Grades: ≥98%. CAS No. 224445-12-9. Molecular formula: C33H40N4·2HCl. Mole weight: 565.6. | |
Coluracetam Quick inquiry Where to buy Suppliers range | MKC-231 (10(-10)-10(-6) moll) significantly increased high affinity choline uptake (HACU) when it was incubated with the hippocampal synaptosomes of ethylcholine mustard aziridinium ion (AF64A) treated rats, but not of normal rats. MKC-231 did not affect the AChE activity, [3H]- quinuclidinyl benzilate binding, and [3H]-pirenzepine binding. Oral administration of MKC-231 (1-10 mg/kg) significantly improved the learning deficits in the Morris' water maze of AF64A-treated rats, but it did not produce any significant side effects, like tremor, salivation or hypothermia, which were observed in rats treated with high doses of tacrine [1]. In acute behavioral experiments, MKC-231 and THA had no significant effect on AF64A-induced memory deficits at any doses tested (0.3, 1.0 and 3.0 mg/kg), whereas Dup 996, at a dose of 1.0 mg/kg, significantly improved memory deficits. In chronic experiments, MKC-231 improved memory deficit at all doses tested (0.3, 1.0, or 3.0 mg/kg p.o., once daily for 11 days) and Dup 996 did so only at a dose of 3.0 mg/kg, whereas THA did not improve memory deficit at any doses tested. Synonyms: Coluracetam; BCI-540; MKC-231; BCI 540; MKC 231; BCI540; MKC231. Grades: >98%. CAS No. 135463-81-9. Molecular formula: C19H23N3O3. Mole weight: 341.4. | |
N-Acetyl-L-aspartyl-L-glutamic acid Quick inquiry Where to buy Suppliers range | white powder. Group: Heterocyclic Organic Compound. Alternative Names: AC-ASP-GLU-OH; ACETYL-D-E; N-acetyl-L-aspartyl-L-glutamate; AC-ASP-GLU H2O; NAAGA; Isospaglumic acid; N-acetyl-L-aspartyl-L-glutamic acid; NAAG Spaglumic acid; Tacrine hydrochloride; SPAGLUMIC ACID; AC-ASP-GLU; Naaxia; N-acetyl-aspartatylglutamate; NAAG. Grades: 96%. CAS No. 3106-85-2. Molecular formula: C11H16N2O8. Mole weight: 304.25. IUPAC Name: 2-[(2-acetamido-4-hydroxy-4-oxobutanoyl)amino]pentanedioic acid. Exact Mass: 304.09100. Boiling Point: 769.5ºC at 760mmHg. Flash Point: 419.1ºC. Density: 1.472g/cm3. InChIKey: OPVPGKGADVGKTG-UHFFFAOYSA-N. H-Bond Donor: 5. H-Bond Acceptor: 8. Safty Description: S26-S36. Hazard statements: Xi: Irritant. |