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2'-Acetyltaxol is a microtubule polymerization-inactive taxol analog. Group: Biochemicals. Grades: Highly Purified. CAS No. 92950-40-8. Pack Sizes: 5mg, 10mg. Molecular Formula: C49H53NO15, Molecular Weight: 895.94. US Biological Life Sciences.
Worldwide
2'-Benzoylcarbonyl D-seco-Taxol
2'-Benzoylcarbonyl D-seco-Taxol is one of Paclitaxel intermediates. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Molecular formula: C55H59NO17. Mole weight: 1006.05.
2-Benzoylcarbonyl D-seco-Taxol
2-Benzoylcarbonyl D-seco-Taxol is an protected intermediate in the synthesis of Paclitaxel (P132500) related compound. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C55H59NO17. US Biological Life Sciences.
Worldwide
2'-Benzoyloxycarbonyl 5-Acetyl D-seco-Taxol
2'-Benzoyloxycarbonyl 5-Acetyl D-seco-Taxol is one of protected Paclitaxel intermediates. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Molecular formula: C55H59NO17. Mole weight: 1006.05.
2-Benzoyloxycarbonyl 5-Acetyl D-seco-Taxol
2-Benzoyloxycarbonyl 5-Acetyl D-seco-Taxol is an protected intermediate in the synthesis of Paclitaxel (P132500) related compound. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C55H59NO17. US Biological Life Sciences.
Worldwide
2'-Benzyloxycarbonyl Nor-D-seco-taxol
2'-Benzyloxycarbonyl Nor-D-seco-taxol is one of Paclitaxel intermediates. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Molecular formula: C55H57NO16. Mole weight: 988.04.
2-Benzyloxycarbonyl Nor-D-seco-taxol
2-Benzyloxycarbonyl Nor-D-seco-taxol is an intermediate in the synthesis of Paclitaxel (P132500) related compound. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C55H57NO16. US Biological Life Sciences.
Worldwide
2'-epi-Taxol
2'-epi-Taxol is one of Paclitaxel impurities. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Synonyms: [2aR-[2aα, 4β, 4aβ, 6β, 9α(αS*, βS*), 11α, 12α, 12aα, 12bα]]-β-(Benzoylamino)-α-hydroxy-6, 12b-bis(acetyloxy)-12-(benzoyloxy)-2a, 3, 4, 4a, 5, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-4, 11-dihydroxy-4a, 8, 13, 13-tetramethyl-5-oxo-7, 11-methano-1H-cyclodeca[3, 4]benz[1, 2-b]oxet-9-yl Ester Benzenepropanoic Acid; 2'-epi-Paclitaxel; 2'-epi-Taxol A. CAS No. 179798-21-1. Molecular formula: C47H51NO14. Mole weight: 853.90.
2-epi-Taxol
2-epi-Taxol can be synthesized from natural Taxol, also known as Paclitaxel (P132500), an antineoplastic. Group: Biochemicals. Grades: Highly Purified. CAS No. 179798-21-1. Pack Sizes: 10mg, 25mg. Molecular Formula: C47H51NO14, Molecular Weight: 853.91. US Biological Life Sciences.
Worldwide
2'-O-(Benzyloxycarbonyl) Taxol
2'-O-(Benzyloxycarbonyl) Taxol is one of protected Paclitaxel intermediates. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Synonyms: 7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete, benzenepropanoic acid deriv.; 2'-(Benzyloxycarbonyl)taxol; [2aR-[2aα , 4β , 4aβ , 6β , 9α (α R*, β S*) , 11α , 12α , 12aα , 12bα ]]-β - (Benzoylamino) -α -[[ (phenylmethoxy) carbonyl]oxy]benzenepropanoic Acid 6,12b-Bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester; (αR,βS)-β-(Benzoylamino)-α-[[(phenylmethoxy)carbonyl]oxy]-benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester; 2'-carboxybenzoylpaclitaxel; 2'-benzyloxycarbonyl-paclixatel; 2'-Z-paclitaxel. Grades: 98%. CAS No. 148930-30-7. Molecular formula: C55H57NO16. Mole weight: 988.04.
2-O-(Benzyloxycarbonyl) Taxol
2-O-(Benzyloxycarbonyl) Taxol is an protected intermediate in the synthesis of Paclitaxel (P132500) related compound. Group: Biochemicals. Grades: Highly Purified. CAS No. 148930-30-7. Pack Sizes: 5mg, 50mg. Molecular Formula: C55H57NO16. US Biological Life Sciences.
Worldwide
3'-epi-Taxol
3'-epi-Taxol is one of Paclitaxel impurities. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Synonyms: 3'-epi-Taxol; SCHEMBL15000506; (2R,3R)-3-(Benzoylamino)-2-hydroxy-3-phenylpropionic acid 1,7beta-dihydroxy-2alpha-(benzoyloxy)-4,10beta-diacetoxy-9-oxo-5beta,20-epoxytaxa-11-ene-13alpha-yl ester; [(1S, 2S, 3R, 4S, 7R, 9S, 10S, 12R, 15S)-4, 12-diacetyloxy-15-[(2R, 3R)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy-1, 9-dihydroxy-10, 14, 17, 17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03, 10.04, 7]heptadec-13-en-2-yl] benzoate. Molecular formula: C47H51NO14. Mole weight: 853.90.
6a-Hydroxy Paclitaxel (6a-Hydroxy Taxol)
The major human metabolite of Paclitaxel. Group: Biochemicals. Alternative Names: 6a-Hydroxy Taxol. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
The compund has been isolated from Taxus brevifolia. It is an antineoplastic that is currently being used in cancer research. Group: Biochemicals. Alternative Names: 7-Epipaclitaxel; 7-Epitaxol; 7-epi-Taxol; Epitaxol. Grades: Plant Grade. CAS No. 105454-04-4. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
7-epi-Taxol
7-epi-Taxol is an active metabolite of taxol, with activity comparable to that of taxol against cell replication, promoting microtubule bundle formation and against microtubule depolymerization. Uses: Scientific research. Group: Natural products. Alternative Names: 7-epi-Paclitaxel. CAS No. 105454-04-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0227.
7-?Xylosyltaxol. Group: Biochemicals. Alternative Names: 7-Xylosylpaclitaxel; Taxol-7-xyloside; 7, 11-Methano-1H-cyclodeca[3, 4]?benz[1, 2-b]oxete, benzenepropanoic Acid Derivative. Grades: Highly Purified. CAS No. 90332-66-4. Pack Sizes: 1mg. Molecular Formula: C52H59NO18, Molecular Weight: 986.02. US Biological Life Sciences.
Worldwide
DEACETYL-10-OXO-7-EPI-TAXOL, 10-
Yew Tree. Group: Taxanes. CAS No. 105377-71-7. Mole weight: 809.85. Appearance: Off white Powder. Catalog: ACM105377717.
Paclitaxel-d5 (Taxol-d5)
An antineoplastic. Used in the study of structure and function of microtubles into tubulin. Group: Biochemicals. Alternative Names: Taxol-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Paclitaxel (Taxol)
Antitumor and antileukemic agent isolated from the bark of the yew tree, Taxus brevifolia. Group: Biochemicals. Alternative Names: Abraxane; Genaxol; Genetaxyl; OncoGel; Onxal; Pacliex; (-)-Paclitaxel; Taxol; Yewtaxan; NSC 125973. Grades: Highly Purified. CAS No. 33069-62-4. Pack Sizes: 50mg, 100mg, 250mg, 500mg. Molecular Formula: C47H51NO14, Molecular Weight: 853.91. US Biological Life Sciences.
Worldwide
10-Deacetyl Baccatin III
A intermediate in the synthesis of Taxol and derivatives. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
13-{[(3-t-Boc)-2,2-dimethyl-4S-phenyl-1,3-oxazolidin-5R-yl]formyl} Δ6,7-Baccatin III
13-{[(3-t-Boc)-2,2-dimethyl-4S-phenyl-1,3-oxazolidin-5R-yl]formyl} Δ6,7-Baccatin III is one of Paclitaxelintermediates. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Synonyms: N-Desbenzoyl-N-tert-butoxycarbonyl-N,O-isopropylidene-6,7-dehydro Taxol; N-Desbenzoyl-N-tert-butoxycarbonyl-N,O-isopropylidene-6,7-dehydro Paclitaxel. Molecular formula: C48H57NO14. Mole weight: 871.96.
13-{[ (3-tert-Butyloxycarbonyl) -2, 2-dimethyl-4S-phenyl-1, 3-oxazolidin-5R-yl]formyl}-7-O- ( (trifluoromethyl) sulfonyl]oxy) Baccatin III
Intermediate in the synthesis of taxol analogs. Group: Biochemicals. Alternative Names: (4S, 5R) -2, 2-Di methyl -4-phenyl -3, 5-oxazolidinedicarboxyl ic Acid 5-[ (2aR, 4S, 4aS, 6R, 9S, 11S, 12S, 12aR, 12bS) -6, 12b-Bis (acetyloxy) -12- (benzoyloxy) -2a, 3, 4, 4a, 5, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-11-hydroxy-4a, 8, 13, 13-tetramethyl-5-oxo-4-[[ (trifluoromethyl) sulfonyl]oxy]-7, 11-methano-1H-cyclodeca[3, 4]benz[1, 2-b]oxet-9-yl] 3-(1,1-dimethylethyl) Ester. Grades: Highly Purified. CAS No. 168120-69-2. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
13-{[(3-tert-Butyloxycarbonyl)-2,2-dimethyl-4S-phenyl-1,3-oxazolidin-5R-yl]formyl} Baccatin III
Intermediate in the synthesis of taxol and its analogs. Group: Biochemicals. Alternative Names: (4S, 5R) -2, 2-Di methyl -4-phenyl -3, 5-oxazolidinedicarboxyl ic Acid 5-[(2aR, 4S, 4aS, 6R, 9S, 11S, 12S, 12aR, 12bS)-6, 12b-Bis(acetyloxy)-12-(benzoyloxy)-2a, 3, 4, 4a, 5, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-4, 11-dihydroxy-4a, 8, 13, 13-tetramethyl-5-oxo-7, 11-methano-1H-cyclodeca[3, 4]benz[1, 2-b]oxet-9-yl] 3-(1,1-dimethylethyl) Ester. Grades: Highly Purified. CAS No. 143527-72-4. Pack Sizes: 2.5mg. US Biological Life Sciences.
2',7-Bis-O-{[(2,2,2,-Trichloroethyl)oxy]carbonyl Paclitaxel is one of Paclitaxel impurities. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Synonyms: 2',7-Bis[(2,2,2-trichloroethoxy)carbonyl]taxol; [2aR-[2aα, 4β, 4aβ, 6β, 9α(αR*, βS*), 11α, 12α, 12aα, 12bα]]-β-(Benzoylamino)-α-[[(2, 2, 2-trichloroethoxy)carbonyl]oxy]-benzenepropanoic Acid 6,12b-Bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-4-[[(2,2,2-trichloroethoxy)carbonyl]oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester; 2',7-Bis-O-{[(2,2,2,-Trichloroethyl)oxy]carbonyl Paclitaxel; (5beta, 7beta, 10beta, 13alpha) -4, 10-Bis (acetyloxy) -13-{[ (2R, 3S) -3-benzamido-3-phenyl-2-{[ (2, 2, 2-trichloroethoxy) carbonyl]oxy}propanoyl]oxy}-1-hydroxy-9-oxo-7-{[ (2, 2, 2-trichloroethoxy) carbonyl]oxy}-5, 20-epoxytax-11-en-2-yl benzoate. Grades: > 98%. CAS No. 100449-86-3. Molecular formula: C53H53Cl6NO18. Mole weight: 1204.70.
2'-O-tert-Butyl(dimethyl)silyl-7-O-triethylsilyl-2-debenzoyl-4-desacetyl Paclitaxel is one of Paclitaxel intermediates. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Synonyms: (αR,βS)-β-(Benzoylamino)-α-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6-(acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-Dodecahydro-11,12,12b-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-[(triethylsilyl)oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester; [2aR-[2aα , 4β , 4aβ , 6β , 9α (α R*, β S*) , 11α , 12α , 12aα , 12bα ]]-β - (Benzoylamino) -α -[[ (1, 1-dimethylethyl) dimethylsilyl]oxy]benzenepropanoic Acid 6-(Acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11,12,12b-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-[(triethylsilyl)oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester; 4-deacetyl-2-debenzoyl-2'-O-tert-butyldimethylsilyl-7-O-(triethylsilyl)taxol; 2'-tert-butyldimethylsilyl-2-debenzoyl-4-deacetyl-7-(triethylsilyl)paclitaxel. Grades: 98%. CAS No. 160768-75-2. Molecular formula: C50H73NO12Si2. Mole weight: 936.28.
2'-O-(tert-Butyldimethylsilyl) Paclitaxel is one of Paclitaxel impurities. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Uses: Paclitaxel derivative as antitumor agent. Synonyms: 2'-O-(tert-Butyldimethylsilyl)taxol; (3xi,5beta,7beta,10beta,13alpha)-4,10-Bis(acetyloxy)-13-{[(2R,3S)-3-benzamido-2-{[tert-butyl(dimethyl)silyl]oxy}-3-phenylpropanoyl]oxy}-1,7-dihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate; 2'-O-TBS-paclitaxel. Grades: 98%. CAS No. 114655-02-6. Molecular formula: C53H65NO14Si. Mole weight: 968.16.
2'-O-(tert-Butyldimethylsilyl) Paclitaxel
Paclitaxel derivative as antitumor agent. Group: Biochemicals. Alternative Names: 2'-O- (tert-Butyldimethylsilyl) taxol. Grades: Highly Purified. CAS No. 114655-02-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
(2R,3S)-3-Phenylisoserine Ethyl Ester
(2R,3S)-3-Phenylisoserine Ethyl Ester is a reactant used in the preparation of Taxotere and Taxol side chain. Group: Biochemicals. Alternative Names: (2R,3S)-3-Amino-2-hydroxy-3-phenylpropionic Acid Ethyl Ester; (αR, βS)- β-Amino-α-hydroxy-benzenepropanoic Acid Ethyl Ester. Grades: Highly Purified. CAS No. 143615-00-3. Pack Sizes: 100mg. US Biological Life Sciences.
(2S,3R)-3-Benzamido-2-hydroxy-3-phenylpropanoic acid can be used as an enantiomeric taxol sidechain or chiral building block. Group: Biochemicals. Grades: Highly Purified. CAS No. 54323-80-7. Pack Sizes: 50mg, 100mg. Molecular Formula: C16H15NO4, Molecular Weight: 285.29. US Biological Life Sciences.
Worldwide
(2S,3R)-N-Boc-3-phenyl Isoserine Methyl Ester
(2S,3R)-N-Boc-3-phenyl Isoserine Methyl Ester acts as a reagent used in the synthesis of of taxol and taxotere C-13 side chains which are important anticancer agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 161759-90-6. Pack Sizes: 5mg, 10mg. Molecular Formula: C15H21NO5, Molecular Weight: 295.33. US Biological Life Sciences.
A protected Paclitaxel (Taxol). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
4-Chloro-L-β-homophenylglycine
4-Chloro-L-β-homophenylglycine is used in the synthesis of N-Benzoyl Phenylisoserinoyl side-chain of the anticancer drug taxol. Synonyms: H-Phg(4-Cl)-(C#CH2)OH; H-β-Phe(4-Cl)-OH; (R)-3-Amino-3-(4-chlorophenyl)propanoic acid. Grades: ≥ 99% (HPLC). CAS No. 131690-61-4. Molecular formula: C9H10ClNO2. Mole weight: 199.64.
6a-Hydroxy Paclitaxel
6α-hydroxy Paclitaxel is a primary metabolite of the anticancer compound paclitaxel (Item No. 10461), produced by the action of the cytochrome P450 isoform CYP2C8.1,2 The generation of 6α-hydroxy paclitaxel by CYP2C8 can be impacted by other drugs (e.g., fluvastatin, Item No. 10010334) or dietary components that interefere with CYP2C8 activity, as well as by CYP2C8 genetic polymorphisms.3,4,5. Group: Biochemicals. Alternative Names: 6α-hydroxy Taxol; βS-(benzoylamino)-αR-hydroxy-(2aR, 3S, 4R, 4aS, 6R, 9S, 11S, 12S, 12aR, 12bS, )-6, 12b-bis(acetyloxy)-12-(benzoyloxy)-2a, 3, 4, 4a, 5, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-3, 4, 11-trihydroxy-4a, 8, 13, 13-tetramethyl-5-oxo-7, 11-methano-1H-cyclodeca[3, 4]benz[1, 2-b]oxet-9-yl ester-benzenepropanoic acid. Grades: Highly Purified. CAS No. 153212-75-0. Pack Sizes: 1mg. Molecular Formula: C??H??NO??, Molecular Weight: 869.91. US Biological Life Sciences.
Worldwide
6α-Hydroxy Paclitaxel
6α-Hydroxy Paclitaxel is the major human metabolite of Paclitaxel is a derivative of Paclitaxel, which is a chemotherapy medication used to treat a number of types of cancer. Synonyms: 6α-Hydroxy Taxol; 6-Hydroxypaclitaxel; Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, (2aR, 3S, 4R, 4aS, 6R, 9S, 11S, 12S, 12aR, 12bS)-6, 12b-bis(acetyloxy)-12-(benzoyloxy)-2a, 3, 4, 4a, 5, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-3, 4, 11-trihydroxy-4 a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-; (2α, 5β, 6α, 7β, 10β, 13α)-4, 10-Diacetoxy-13-{[(2R, 3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoyl]oxy}-1, 6, 7-trihydroxy-9-oxo-5, 20-epoxytax-11-en-2-yl benzoate. Grades: 90%. CAS No. 153212-75-0. Molecular formula: C47H51NO15. Mole weight: 869.90.
6α-Hydroxy Paclitaxel-d5
The major human labeled metabolite of Paclitaxel. Group: Biochemicals. Alternative Names: 6α-Hydroxy Taxol-d5. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
7,13-Bis-O-(triethylsilyl)-10-deacetyl Baccatin III
10-Deacetylbaccatin III (D198250) derivative, used in the preparation of taxol analogs with antitumoral and antineoplastic properties. Group: Biochemicals. Alternative Names: [2aR-(2aα,4 β,4a β,6 β , 9α , 11α , 12α , 12aα , 12bα )]-12b- (Acetyloxy)-12- (benzoyloxy)-1, 2a, 3, 4, 4a, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-6, 11-dihydroxy-4a, 8, 13, 13-tetramethyl-4, 9-bis[ (triethylsilyl)oxy]-7, 11-methano-5H-cyclodeca[3, 4]benz[1, 2-b]oxet-5-one. Grades: Highly Purified. CAS No. 183133-99-5. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
7-Epi 10-Desacetyl Paclitaxel
Paclitaxel impurity. Paclitaxel related compound B. Group: Biochemicals. Alternative Names: 10-Deacetyl-7-epi-taxol; 10-Deacetyl-7-epitaxol; 10-Desacetyl-7-epipaclitaxel; 7-Epi-10-deacetyltaxol; 7-epi-10-Deacetyltaxol; Ormosin VI. Grades: Highly Purified. CAS No. 78454-17-8. Pack Sizes: 2.5mg. US Biological Life Sciences.
Baccatin III (B101000) derivative, used in the preparation of taxol analogs as antineoplastic agents and taxoids derivatives useful due to their ability to activate murine macrophages and inhibit the growth of macrophage-like cells. Group: Biochemicals. Alternative Names: [2aR-(2aα,4 β,4a β,6 β, 11α, 12α, 12aα, 12bα)]-6, 12b-Bis(acetyloxy)-12-(benzoyloxy)-2a, 4, 4a, 10, 11, 12, 12a, 12b-octahydro-11-hydroxy-4a, 8, 13, 13-tetramethyl-4-[(triethylsilyl)oxy]-7, 11-methano-1H-cyclodeca[3, 4]benz[1, 2-b]oxete-5, 9(3H, 6H)-dione. Grades: Highly Purified. CAS No. 150665-56-8. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
8-epi-10-Deacety Baccatin III
An impurity of Baccatin III which is a precursor to the anti-cancer drug paclitaxel (Taxol). Synonyms: 92999-93-4; 8-epi-10-Deacetylbaccatin III7,11-Methano-5H-cyclodeca(3,4)benz(1,2-b)oxet-5-one, 12b-(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-, (2aR-(2aalpha, 4beta, 4aalpha, 6beta, 9alpha, 11alpha, 12alpha, 12aalpha, 12balpha))-. Grades: > 95%. CAS No. 92999-93-4. Molecular formula: C29H36O10. Mole weight: 544.6.
Cephalomannine - Product ID: NST-10-218. Category: Terpenes. Alternative Names: Taxol B. Purity: 98%. Test method: HPLC. CAS No. 71610-00-9. Pack Sizes: 0,05g, 0,1g, 0,25g, 0,5g. Appearance: White Powder. Molecular formula: C45H53NO14. Mole weight: 831.9. Storage: +2 +8 °C.
Docetaxel
An antineoplastic. An antimitotic agent that promotes the assembly of microtublules and inhibits their depolymerization to free tubulin. Docetaxel is of the chemotherapy drug class; taxane, and is a semi-synthetic analogue of paclitaxel (Taxol), an extract from the bark of the rare Pacific yew tree Taxus brevifolia. Due to scarcity of paclitaxel, extensive research was carried out leading to the formulation of docetaxel - an esterified product of 10-deacetyl baccatin III, which is extracted from the renewable and more readily available leaves of the European yew tree. Group: Biochemicals. Alternative Names: Docecad; N-debenzoyl-N-tert-butoxycarbonyl-10-deacetyltaxol; NSC 628503; RP 56976; Taxoltere metro; docetaxol; Taxotere. Grades: Highly Purified. CAS No. 114977-28-5. Pack Sizes: 100mg, 500mg, 1g. US Biological Life Sciences.
Worldwide
Docetaxel Related Compound 1 ((2R, 3S)-3-Phenylisoserine)
Intermediate for the synthesis of taxol. Synonyms: (2R,3S)-3-Amino-2-hydroxy-3-phenyl-propanoic acid. Grades: ≥ 98% (NMR). CAS No. 136561-53-0. Molecular formula: C9H11NO3. Mole weight: 181.19.
Docetaxel Trihydrate
Docetaxel Trihydrate (RP-56976 Trihydrate) is an antineoplastic agent and inhibits microtubule depolymerization with an IC 50 value of 0.2 μM [1]. Docetaxel Trihydrate is a semisynthetic analog of taxol and attenuates the effects of bcl-2 and bcl-xL gene expression. Docetaxel Trihydrate arrests the cell cycle at G2/M and leads to cell apoptosis [1] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RP-56976 Trihydrate. CAS No. 148408-66-6. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0011A.
Epothilone A
Epothilone A is a microtubule inhibitor isolated from the myxobacteria, Sorangium cellulosum. Epothilone A acts by stabilising microtubule formation at the taxol binding site and causes cell cycle arrest at the G2/M transition, leading to cytotoxicity. Epothilone A is under investigation as an antitumor agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 152044-53-6. Pack Sizes: 100ug. US Biological Life Sciences.
Worldwide
Epothilone B
Epothilone B is a microtubule inhibitor isolated from the myxobacteria, Sorangium cellulosum. Like epothilone A, epothilone B acts by stabilising microtubule formation at the taxol binding site and causes cell cycle arrest at the G2/M transition, leading to cytotoxicity. Group: Biochemicals. Grades: Highly Purified. CAS No. 152044-54-7. Pack Sizes: 100ug. US Biological Life Sciences.
Worldwide
Flutax 1
Flutax 1 is a fluorescent taxol derivative that binds to the taxol microtubule binding site with high affinity (Ka ~ 107M-1). Flutax 1 is useful for direct imaging of the microtubule cytoskeleton. Excitation maximum ~ 495 nm; emission maximum ~ 520 nm. Group: Biochemicals. Alternative Names: (2aR, 4S, 4aS, 6R, 9S, 11S, 12S, 12aR, 12bS)-6, 12b-Bis(acetyloxy)-9-[(2R, 3S)-3-(benzoylamino)-2-hydroxy-1-oxo-3-phenylpropoxy]-12-(benzoyloxy)-2a, 3, 4, 4a, 5, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-11-hydroxy-4a, 8, 13, 13-tetramethyl-5-oxo-7, 11-methano-1H-cyclodeca[3, 4]benz[1, 2-b]oxet-4-yl Ester N-[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)carbonyl]-L-alanine; 7-O-[N-(4-Fluoresceincarbonyl)-L-alanyl] Taxol. Grades: Highly Purified. CAS No. 191930-58-2. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Fmoc-(2R,3S)-3-phenylisoserine
Intermediate for the synthesis of taxol. Synonyms: (2R,3S)-3-(Fmoc-amino)-2-hydroxy-3-phenyl-propanoic acid. Grades: ≥ 99% (HPLC). CAS No. 252206-27-2. Molecular formula: C24H21NO5. Mole weight: 403.43.
FSLLRY-NH2
FSLLRY-NH2 is a selective PAR2 peptide antagonist. It reverses taxol-induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR mice, also suppresses ERK activation and collagen production in isolated cardiac fibroblasts. Synonyms: [Phe1,Ser2,Tyr6]-PAR-1 (1-6) amide (human). CAS No. 245329-02-6. Molecular formula: C39H60N10O8. Mole weight: 796.97.
FSLLRY-NH2 TFA
FSLLRY-NH2 TFA is a selective PAR2 peptide antagonist. It reverses taxol-induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR mice, and also suppresses ERK activation and collagen production in isolated cardiac fibroblasts. Synonyms: H-Phe-Ser-Leu-Leu-Arg-Tyr-NH2.TFA; L-phenylalanyl-L-seryl-L-leucyl-L-leucyl-L-arginyl-L-tyrosinamide trifluoroacetic acid. Grades: ≥95%. Molecular formula: C41H61F3N10O10. Mole weight: 910.99.
HMN-176
HMN-176 is an active metabolite of the synthetic antitumor compound HMN-214. HMN-176 shows potent cytotoxicity toward various human tumor cell lines, and in mitotic cells, it causes cell cycle arrest at M phase through the destruction of spindle polar bodies, followed by the induction of DNA fragmentation. However, no direct interactions of HMN-176 with tubulin are observed. Moreover, in animal models, it was observed that oral administration of the prodrug HMN-214 caused no significant nerve toxicity, a severe side effect often associated with microtubule binding agents such as Taxol and VCR.3 In Phase I clinical trials, HMN-214 has caused sensory neuropathy and ileus in some patients. However, the grade and frequency of these adverse effects were much lower than those of typical microtubule binding agents. As expected from the mechanism of action of HMN-214 (induction of G2-M arrest in dividing cells), the main adverse effect was neutropenia. (Source: CANCER RESEARCH 63, 6942 -6947). Group: Inhibitors. Alternative Names: HMN176; HMN 176; HMN-176. CAS No. 173529-10-7. Molecular formula: C20H18N2O4S. Mole weight: 382.43. Appearance: Solid powder. Purity: >98%. IUPACName: (E) -4- (2- (4-methoxyphenylsulfonamido) styryl) pyridine 1-oxide. Canonical SMILES: O=S (NC1=CC=CC=C1/C=C/C2=CC=[N+] ([O-])C=C2) (C3=CC=C (OC)C=C3)=O. Catalog: ACM173529107.
HMN-176
HMN-176 is an active metabolite of the synthetic antitumor compound HMN-214. HMN-176 shows potent cytotoxicity toward various human tumor cell lines, and in mitotic cells, it causes cell cycle arrest at M phase through the destruction of spindle polar bodies, followed by the induction of DNA fragmentation. However, no direct interactions of HMN-176 with tubulin are observed. Moreover, in animal models, it was observed that oral administration of the prodrug HMN-214 caused no significant nerve toxicity, a severe side effect often associated with microtubule binding agents such as Taxol and VCR.3 In Phase I clinical trials, HMN-214 has caused sensory neuropathy and ileus in some patients. However, the grade and frequency of these adverse effects were much lower than those of typical microtubule binding agents. As expected from the mechanism of action of HMN-214 (induction of G2-M arrest in dividing cells), the main adverse effect was neutropenia. Synonyms: HMN 176; HMN176; (E) -4- (2- (2- (N- ( (p-Methoxyphenyl) sulfonyl) amino) phenyl) ethenyl) pyridine 1-oxide. CAS No. 173529-10-7. Molecular formula: C20H18N2O4S. Mole weight: 382.43.
[ (Methoxy) methyl] triphenylphosphonium Chloride
[ (Methoxy) methyl] triphenylphosphonium Chloride is used in the synthesis of Cephalotaxine (C261050), an antiviral and antitumor agent. Also used in the synthesis of Taxol A fragment. Group: Biochemicals. Alternative Names: (Methoxymethyl) triphenylphosphonium Chloride; (Methoxymethyl) triphenylphosphonium Chloride; NSC 49223; Triphenyl (methoxymethyl) phosphonium Chloride. Grades: Highly Purified. CAS No. 4009-98-7. Pack Sizes: 10g. US Biological Life Sciences.
Worldwide
N-Benzoyl-(2R,3S)-3-phenylisoserine
N-Benzoyl-(2R,3S)-3-phenylisoserine is a Taxol C-13 Side Chain and crucial for the strong antitumor activity of Taxol [1]. Uses: Scientific research. Group: Natural products. CAS No. 132201-33-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2380.
N-Debenzoyl-7-{[(2,2,2,-trichloroethyl)oxy]carbonyl} Paclitaxel is one of Paclitaxel impurities. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Uses: A paclitaxel (taxol). Synonyms: N-Debenzoyl-7-[[(2,2,2-trichloroethoxy)carbonyl]oxy]taxol. Grades: > 98%. CAS No. 114915-15-0. Molecular formula: C43H48Cl3NO15. Mole weight: 925.20.