Thromboxane Suppliers USA
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Product | Description | |
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Thromboxane A2 Quick inquiry Where to buy Suppliers range | Thromboxane A2 is the predominant cyclooxygenase product formed from arachidonic acid (AA) in human platelets. Thromboxane A2 is neither stored in platelets, nor formed in the absence of activation. However, it is synthesized in response to platelet activation by a wide variety of receptor-dependent and -independent platelet agonists. Synonyms: thromboxane A2; TXA2; 57576-52-0; TXA-2; Rabbit aorta contracting substance; 9S,11S-epoxy,15S-hydroxy-thromboxa-5Z,13E-dien-1-oic acid; 4C2A5G825S; Thromboxa-5,13-dien-1-oic acid, 9,11-epoxy-15-hydroxy-, (5Z,9alpha,11alpha,13E,15S)-; Benz(a)anthracene-1,7,12(2H)-trione, 3,4-dihydro-3,6,8-trihydroxy-3-methyl-, (-)-; (Z)-7-[(1S,3R,4S,5S)-3-[(E,3S)-3-hydroxyoct-1-enyl]-2,6-dioxabicyclo[3.1.1]heptan-4-yl]hept-5-enoic acid; (5Z,13E)-(15S)-9alpha,11alpha-Epoxy-15-hydroxythromboxa-5,13-dienoate; (5Z,9alpha,11alpha,13E,15S)-9,11-Epoxy-15-hydroxythromboxa-5,13-dien-1-oic acid. Grades: > 95%. CAS No. 57576-52-0. Molecular formula: C20H32O5. Mole weight: 352.48. | |
Thromboxane b2 Quick inquiry Where to buy Suppliers range | Thromboxane b2. Group: Heterocyclic Organic Compound. Alternative Names: THROMBOXANE B2;TXB2;9ALPHA,11,15S-TRIHYDROXYTHROMBA-5Z,13E-DIEN-1-OIC ACID;[5Z,9ALPHA,11RS,13E,15S]-9,11,15-TRIHYDROXYTHROMBOXA-5,13-DIEN-1-OIC ACID;(5z,9α,11rs,13e,15s)-9,11,15-trihydroxythromboxa-5,13-dien-1-oic acid;(E)-7-[(2S,3S,4S)-4,6-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]oxan-3-yl]hept-5-enoic acid;TXB2,(5Z,9α,11RS,13E,15S)-9,11,15-Trihydroxythromboxa-5,13-dien-1-oicacid;(5Z,13E,15S)-9α,11,15-Trihydroxythromboxa-5,13-dien-1-oic acid. CAS No. 54397-85-2. Molecular formula: C20H34O6. Mole weight: 370.48. Safty Description: 22-36-45-36/37/39-26. Hazard statements: Xn, T. | |
Thromboxane B2 Quick inquiry Where to buy Suppliers range | Thromboxane B2 is a stable metabolite of Thromboxane A2 and is important in the platelet-release reaction. Synonyms: 9α,11,15S-trihydroxythromba-5Z,13E-dien-1-oic acid; TXB2. Grades: > 95%. CAS No. 54397-85-2. Molecular formula: C20H34O6. Mole weight: 370.49. | |
Thromboxane B2 Quick inquiry Where to buy Suppliers range | Thromboxane B2. Uses: For analytical and research use. Group: Building Blocks. CAS No. 54397-85-2. IUPAC Name: (Z)-7-[(2R,3S,4S)-4,6-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]oxan-3-yl]hept-5-enoic acid. Molecular formula: C20H34O6. Mole weight: 370.48. Catalog: APS54397852. SMILES: CCCCC[C@H] (O)\C=C\[C@H]1OC (O)C[C@H] (O)[C@@H]1C\C=C/CCCC (=O)O. Format: Neat. | |
11-Dehydro-2,3-dinor thromboxane b2 Quick inquiry Where to buy Suppliers range | 11-Dehydro-2,3-dinor thromboxane b2. Group: Heterocyclic Organic Compound. Alternative Names: 9ALPHA, 15S-DIHYDROXY-11-OXO-2,3-DINOR-THROMBA-5Z, 13E-DIEN-1-OIC ACID;11-DEHYDRO-2,3-DINOR THROMBOXANE B2. CAS No. 79250-60-5. Molecular formula: C18H28O6. Mole weight: 340.41. | |
11-Dehydro thromboxane B2 Quick inquiry Where to buy Suppliers range | 11-Dehydro thromboxane B2. Group: Biochemicals. Alternative Names: (5Z)-7-[(2R,3S,4S)-Tetrahydro-4-hydroxy-2-[(1E,3S)-3-hydroxy-1-octen-1-yl]-6-oxo-2H-pyran-3-yl]-5-heptenoic acid; 11-Dehydro-TXB2; 11-keto-thromboxane B2. Grades: Highly Purified. CAS No. 67910-12-7. Pack Sizes: 1mg, 2mg, 5mg. Molecular Formula: C20H32O6. US Biological Life Sciences. | Worldwide |
11-Dehydro Thromboxane B2-d4 Quick inquiry Where to buy Suppliers range | Isotope labelled 11-Dehydro Thromboxane B2, a metabolite of Thromboxane that is an in vivo markers of oxidative stress and platelet activation. It is associated with adverse cardiovascular events in Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT). Group: Biochemicals. Grades: Highly Purified. CAS No. 1240398-15-5. Pack Sizes: 250ug, 2.5mg. Molecular Formula: C20H28D4O6, Molecular Weight: 372.49. US Biological Life Sciences. | Worldwide |
2, 3-Dinor Thromboxane B2-d9 Quick inquiry Where to buy Suppliers range | 2, 3-Dinor Thromboxane B2-d9 serves as an internal standard for the quantification of 2,3-Dinor TXB2. 2, 3-Dinor TXB2 is an abundant urinary metabolite of TXB2 and can be used as a marker in vivo TXA2 synthesis. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25ug, 50ug. Molecular Formula: C18H21D9O6, Molecular Weight: 351.48. US Biological Life Sciences. | Worldwide |
Pinane Thromboxane A2 Quick inquiry Where to buy Suppliers range | Pinane Thromboxane A2 (PTA2) is a stable analog of TXA2. It is a TXA2R antagonist and a TXA synthase inhibitor. It inhibits coronary artery constriction and platelet aggregation. Synonyms: 15(S)-Pinane Thromboxane A2; Pinane TXA2; PTA2; 7-[3-(3-hydroxyoct-1-enyl)-6,6-dimethyl-2-bicyclo[3.1.1]heptanyl]hept-5-enoic acid. Grades: ≥98%. CAS No. 71111-01-8. Molecular formula: C24H40O3. Mole weight: 376.6. | |
12(S)-HHTrE Quick inquiry Where to buy Suppliers range | 12(S)-HHTrE is a product of the cyclooxygenase (COX) pathway and one of the primary arachidonic acid metabolites of human platelets. It is biosynthesized by thromboxane (TXA2) synthase from prostaglandin H2 (PGH2) concurrently with TXA2. Synonyms: 12(S)-HHT; 12-hydroxyheptadecatrienoic acid. Grades: ≥95%. CAS No. 54397-84-1. Molecular formula: C17H28O3. Mole weight: 280.4. | |
12(S)-HHTrE Quick inquiry Where to buy Suppliers range | 12(S)-HHTrE is a metabolite of arachidonic acid (A3303), which is an essential fatty acid and a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. Arachidonic Acid occurs in liver, brain, glandular organs, and depot fats of animals, in small amounts in human depot fats, and Arachidonic Acid is also a constituent of animal phosphatides. Group: Biochemicals. Grades: Highly Purified. CAS No. 54397-84-1. Pack Sizes: 500ug, 5mg. Molecular Formula: C17H28O3, Molecular Weight: 280.399999999999. US Biological Life Sciences. | Worldwide |
13-APA Quick inquiry Where to buy Suppliers range | 13-APA is a specific thromboxane A2 receptor (TP) antagonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 71629-07-7. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C19H37NO2, Molecular Weight: 311.5. US Biological Life Sciences. | Worldwide |
1,3-bis(4-((E)-2-carboxyvinyl)benzyl)-1H-imidazol-3-ium bromide Quick inquiry Where to buy Suppliers range | 1,3-bis(4-((E)-2-carboxyvinyl)benzyl)-1H-imidazol-3-ium bromide is an impurity of Ozagrel, an antiplatelet drug that acts as a thromboxane A2 synthesis inhibitor. Synonyms: (E)-3-(4-((1-(4-((E)-2-Carboxyvinyl)benzyl)-1H-imidazol-3-ium-3-yl)methyl)phenyl)acrylate; 883942-98-1. CAS No. 883942-98-1. Molecular formula: C23H21BrN2O4. Mole weight: 469.34. | |
14,15-Epoxyeicosatrienoic Acid (±14,15-EET) Quick inquiry Where to buy Suppliers range | Epoxyeicosatrienoic Acid (EET) has antihypertensive and anti-inflammatory properties and play a role in the maintenance of renal vascular function. N,?N'-?dicyclohexylurea (DCU) increased release of 14,15-EET when the cells were stimulated with a calcium ionophore. Also, it is derived from Arachidonic Acid, which is an essential fatty acid and a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. Arachidonic Acid occurs in liver, brain, glandular organs, and depot fats of animals, in small amounts in human depot fats, and Arachidonic Acid is also a constituent of animal phosphatides. Group: Biochemicals. Alternative Names: (5Z,8Z,11Z)-13-(3-Pentyl-2-oxiranyl)-5,8,11-tridecatrienoic Acid; 14(15)-EET; 14(15)-Epoxy-5Z,8Z,11Z-eicosatrienoic Acid; (±)14,15-EET; (±)14,15-EpETrE; (all-Z)-13-(3-Pentyloxiranyl)-5,8,11-tridecatrienoic Acid. Grades: Highly Purified. CAS No. 197508-62-6. Pack Sizes: 50ug, 100ug, 500ug. Molecular Formula: C??H??O?, Molecular Weight: 320.47. US Biological Life Sciences. | Worldwide |
2-Hydroxymethyl-2,3-dihydrobenzofuran Quick inquiry Where to buy Suppliers range | 2-Hydroxymethyl-2,3-dihydrobenzofuran is a reactant used in the preparation of thromboxane A2 agonist indane derivatives. Group: Biochemicals. Alternative Names: 2-Hydroxymethyl-2,3-dihydrobenzofuran; 2,3-Dihydro-2-benzofuranmethanol. Grades: Highly Purified. CAS No. 66158-96-1. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
(2R,4R)-trans-Ketoconazole Quick inquiry Where to buy Suppliers range | (2R,4R)-trans-Ketoconazole is an isomer of Ketoconazole (K186000). Ketoconazole inhibits cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo. It has antimetastatic and antineoplastic activity and is an orally active 5-lipoxygenase and thromboxane synthase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 142128-58-3. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C26H28Cl2N4O4, Molecular Weight: 531.429999999999. US Biological Life Sciences. | Worldwide |
(2R,4R)-trans-Ketoconazole-d8 Quick inquiry Where to buy Suppliers range | (2R,4R)-trans-Ketoconazole-d8 is the isotope labelled analog of (2R,4R)-trans-Ketoconazole (K186015); an isomer of Ketoconazole (K186000). Ketoconazole inhibits cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo. It has antimetastatic and antineoplastic activity and is an orally active 5-lipoxygenase and thromboxane synthase inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C26H20D8Cl2N4O4, Molecular Weight: 539.48. US Biological Life Sciences. | Worldwide |
2-(Tosyloxy)methyl-2,3-dihydrobenzofuran Quick inquiry Where to buy Suppliers range | Protected 2-Hydroxymethyl-2,3-dihydrobenzofuran , a reactant in the preparation of thromboxane A2 agonist indane derivatives. Group: Biochemicals. Alternative Names: 2,3-Dihydro-2-benzofuranmethanol 4-Methyl Benzene sulfonate; 2,3-Dihydro-2-benzofuranmethanol p-Toluenesulfonate. Grades: Highly Purified. CAS No. 94709-25-8. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
3-Bromo-5-iodobenzoic Acid Quick inquiry Where to buy Suppliers range | 3-Bromo-5-iodobenzoic Acid can be used as a starting material in the synthesis of 3- {3- [2- (4-Chloro Benzene sulfonamido) ethyl] -5- (4-fluorobenzyl) phenyl} propionic Acid, a potent thromboxane receptor antagonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 188815-32-9. Pack Sizes: 1g, 5g. Molecular Formula: C7H4BrIO2, Molecular Weight: 326.91. US Biological Life Sciences. | Worldwide |
ACA - CAS 110683-10-8 Quick inquiry Where to buy Suppliers range | A cell-permeable inhibitor of phospholipase A2 that blocks epinephrine-stimulated thromboxane production in platelets. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 110683-10-8. Pack Sizes: 25MG. Mole weight: 337.41. Catalog: AP110683108. Assay: ≥99% (HPLC). | |
all cis-5,8,11,14,17-Eicosapentaenoic Acid Ethyl Ester Quick inquiry Where to buy Suppliers range | all cis-5,8,11,14,17-Eicosapentaenoic Acid Ethyl Ester is an omega-3 fatty acid agent. It is important polyunsaturated fatty acid of the marine food chain. It serves as a precursor of the prostaglandin-3 and thromboxane-3 families. It differs from arachidonic acid by the extra double bond between the third and fourth carbons from the "methyl end" of the molecule. It reduces non-high-density lipoprotein cholesterol, lipoprotein-associated phospholipase A2, apolipoprotein B, very low-density lipoprotein cholesterol, and total cholesterol. It reduces the TG levels and improved other lipid parameters without significantly increasing the LDL cholesterol levels. It is used in combination with changes in diet to lower triglyceride levels in adults with severe (≥ 500 mg/dL) hypertriglyceridemia. It has anti-inflammatory and cardiovascular benefits. It may alter the expression of genes related to fatty acid metabolism. It was the second class of fish oil-based drug to be approved for use as a drug. It was developed by Amarin Corporation. It has been listed. Uses: All cis-5,8,11,14,17-eicosapentaenoic acid ethyl ester reduces non-high-density lipoprotein cholesterol, lipoprotein-associated phospholipase a2, apolipoprotein b, very low-density lipoprotein cholesterol, and total cholesterol. it has anti-inflammatory and cardiovascular benefits. Synonyms: Eicosapentaenoic Acid Ethyl Ester;(5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic Acid Ethyl Ester;(all-Z)-5,8,11,14,17-Eicosapentaenoic Acid Ethyl Ester;cis-Eicosapentaenoic Acid Ethyl Ester;Ethyl icosapentate; Epadel;Ethyl eicosapentaenoate;Vascepa;EPA ethyl ester;Ethyl (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoate. Grades: >98%. CAS No. 86227-47-6. Molecular formula: C22H34O2. Mole weight: 330.50. | |
Arachidonic acid Quick inquiry Where to buy Suppliers range | Arachidonic acid is an essential fatty acid and a precursor in the biosynthesis of thromboxanes, prostaglandins and leukotrienes. It is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. It is an important cellular signaling mediator in a variety of biological processes, including smooth chemotaxis, muscle contraction, apoptosis, cell proliferation and differentiation. It exits in liver, brain, glandular organs, and depot fats of animals and a constituent of animal phosphatides. It could bind to the subunit of G protein and inhibit the activity of Ras GTPase-activating proteins (GAPs). It stimulates adhesion of MDA-MB-435 human metastatic cancer cells to extracellular matrix molecules. Synonyms: Arachidonate. Grades: 98 %. CAS No. 506-32-1. Molecular formula: C20H32O2. Mole weight: 304.47. | |
Arachidonic acid-[13C20] Quick inquiry Where to buy Suppliers range | Labelled Arachidonic acid. Arachidonic acid is an essential fatty acid and a precursor in the biosynthesis of thromboxanes, prostaglandins and leukotrienes. It is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. It is an important cellular signaling mediator in a variety of biological processes, including smooth chemotaxis, muscle contraction, apoptosis, cell proliferation and differentiation. It exits in liver, brain, glandular organs, and depot fats of animals and a constituent of animal phosphatides. It could bind to the subunit of G protein and inhibit the activity of Ras GTPase-activating proteins (GAPs). It stimulates adhesion of MDA-MB-435 human metastatic cancer cells to extracellular matrix molecules. Grades: > 98%. Molecular formula: [13C]20H32O2. Mole weight: 324.32. | |
Arachidonic Acid Alkyne Quick inquiry Where to buy Suppliers range | Arachidonic Acid Alkyne is a metabolite of Arachidonic Acid (A3303). Arachidonic Acid is an essential fatty acid and a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. Arachidonic Acid occurs in liver, brain, glandular organs, and depot fats of animals, in small amounts in human depot fats, and Arachidonic Acid is also a constituent of animal phosphatides. Group: Biochemicals. Grades: Highly Purified. CAS No. 1219038-32-0. Pack Sizes: 100ug, 500ug. Molecular Formula: C20H28O2, Molecular Weight: 300.44. US Biological Life Sciences. | Worldwide |
Bioactive Lipid Compound Library Quick inquiry Where to buy Suppliers range | A unique collection of 385 bioactive lipids related compounds for high throughput screening (HTS) and high content screening (HCS), including Agonists & Antagonists, Endocannabinoids, Farnesyl/geranylgeranyl derivates, HETEs deHETEs, hepoxilins, Polyunsaturated fatty acids, Leukotrienes, lipoxins, LPA & phosphatidic acids, Octadecanoids, PAFs, Prostaglandins & thromboxanes, Retinoids, vitamin D metabolites, Sphingolipids, etc. ; - Targets include GPCR, HDAC, PPAR, DNA Alkylating, EGFR, etc. ; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L7000. Categories: Bioactive Lipid Compounds Libraries. | |
BM 567 Quick inquiry Where to buy Suppliers range | Thromboxane A2 (TXA2) is a potent thrombogenic and vasoconstrictor eicosanoid. It has been reported as a causal factor in the onset of stroke and myocardial infarction. BM 567 is a dual acting antithrombogenic agent, which is acting as an inhibitor of thromboxane A2 (TXA2) synthase and an antagonist of the TP receptor. It also antagonizes the vascular smooth muscle TP receptor with an IC50 value of 1.1 nM. Synonyms: BM567; BM-567. Grades: ≥98%. CAS No. 284464-77-3. Molecular formula: C18H28N4O5S. Mole weight: 412.5. | |
CAY10535 Quick inquiry Where to buy Suppliers range | TPα and TPβ are two isoforms of the human TP receptor, which is the G protein-coupled receptor (GPCR) that mediates the actions of thromboxane A2 (TXA2). CAY10535 is a TP receptor antagonist that shows ~20-fold selectivity for TPβ with IC50 of 99 nM than TPα with IC50 of 1970 nM in the inhibition of U46619-mediated Ca2+ mobilization. Synonyms: CAY 10535; CAY-10535. Grades: ≥98%. CAS No. 945716-28-9. Molecular formula: C18H21N3O7S. Mole weight: 423.4. | |
Dimethyl (3-phenoxy-2-oxoproyl)phosphonate Quick inquiry Where to buy Suppliers range | Dimethyl (3-phenoxy-2-oxoproyl)phosphonate Travopropst (T715600), a selective FP prostaglandin receptor agonist. Isopropyl ester of (+)-fluprostenol. Antiglaucoma. Used in the synthesis ofnovel prostanoid thromboxane A2 agonists. Group: Biochemicals. Alternative Names: P- (2-oxo-3-Phenoxypropyl) phosphonic Acid Dimethyl Ester; (2-oxo-3-Phenoxypropyl) phosphonic Acid Dimethyl Ester; (2-Oxo-3-phenoxypropyl) phosphonic Acid Dimethyl Ester; Dimethyl (2-oxo-3-phenoxypropyl) phosphonate; Dimethyl (3-Phenoxyacetonyl) phosphonate; Dimethyl 3-{Phenoxy-2-oxopropylphosphonate. Grades: Highly Purified. CAS No. 40665-68-7. Pack Sizes: 2.5g. US Biological Life Sciences. | Worldwide |
(E)-3-(4-((1H-imidazol-1-yl)methyl)phenyl)-1-(1H-imidazol-1-yl)prop-2-en-1-one Quick inquiry Where to buy Suppliers range | (E)-3-(4-((1H-imidazol-1-yl)methyl)phenyl)-1-(1H-imidazol-1-yl)prop-2-en-1-one is an impurity of Ozagrel, an antiplatelet drug that acts as a thromboxane A2 synthesis inhibitor. Synonyms: (E)-3-(4-((1H-imidazol-1-yl)methyl)phenyl)-1-(1H-imidazol-1-yl)prop-2-en-1-one; 2452215-05-1. CAS No. 2452215-05-1. Molecular formula: C16H14N4O. Mole weight: 278.32. | |
Eicosapentaenoic acid Quick inquiry Where to buy Suppliers range | Important polyunsaturated fatty acid of the marine food chain that serves as a precursor for the prostaglandin-3 and thromboxane-3 families. It differs from arachidonic acid (the eicosatetraenoic acid that is a precursor for the prostaglandin and thromboxane-2 families) by the extra double bond between the third and fourth carbons from the methyl end of the molecule. Antilipemic. Group: Biochemicals. Alternative Names: (5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic Acid; (all-Z)-5,8,11,14,17-Eicosapentaenoic Acid; EPA; EPA 45G; Icosapent; Icosapentaenoic Acid; Incromega E 7010SR; Ropufa 70; Timnodonic Acid. Grades: Highly Purified. CAS No. 10417-94-4. Pack Sizes: 10g. Molecular Formula: C20H30O2, Molecular Weight: 302.45. US Biological Life Sciences. | Worldwide |
Eicosapentaenoic Acid Quick inquiry Where to buy Suppliers range | Eicosapentaenoic acid (EPA) is an omega-3 fatty acid found in fish oil. It acts as a precursor to prostaglandin-3 and thromboxane-3 families. EPA decreases serum lipid concentration, reduces the risk of cardiovascular disorders and suppresses platelet aggregation. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Timnodonic acid; Icosapent; Icosapentaenoic acid; EPA; (5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic Acid; (all-Z)-5,8,11,14,17-Eicosapentaenoic Acid; Incromega E 7010SR; Ropufa 70; cis-5,8,11,14,17-Eicosapentaenoic acid; 5Z,8Z,11Z,14Z,17Z-Eicosapentaenoic acid; (5Z,8Z,11Z,14Z,17Z)-Icosapentaenoic acid; all-cis-5,8,11,14,17-icosapentaenoic acid. Grades: 98%. CAS No. 10417-94-4. Molecular formula: C20H30O2. Mole weight: 302.46. | |
(E)-Ozagrel hydrochloride Quick inquiry Where to buy Suppliers range | Ozagrel HCl is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia. Uses: Enzyme inhibitors. Synonyms: ozagrel hydrochloride; OKY-046 hydrochloride. Grades: >98%. CAS No. 78712-43-3. Molecular formula: C13H13ClN2O2. Mole weight: 264.71. | |
Epoprostenol Sodium Quick inquiry Where to buy Suppliers range | Epoprostenol Sodium is the sodium salt form of epoprostenol, which is a synthetic prostacyclin. It has vasodilatory and anticoagulant activity. It is a short-lived product of the cyclooxygenase pathway in vascular endothelial cells. It prevents the formation of platelet plugs and is an effective vasodilator. It is a potent inhibitor of platelet aggregation by antagonizing thromboxane A2 and stimulating platelet adenylyl cyclase. It directly simulates prostaglandin receptors in arterial vascular smooth muscle, thereby causing vasodilatation. lt is also used for the treatment of pulmonary hypertension. It is biosynthesized enzymatically from prostaglandin endoperoxides in human vascular tissue. It is vasoprotective, protecting arterial walls from injury-induced lesions and cytoprotective in the liver and gastrointestinal tract. It was developed by GlaxoSmithKline and has been listed. Uses: Epoprostenol sodium has vasodilatory and anticoagulant activity. it prevents the formation of platelet plugs and is an effective vasodilator. lt is also used for the treatment of pulmonary hypertension. Synonyms: Prostacyclin Sodium Salt; (5Z,9α,11α,13E,15S)-6,9-epoxy-11,15-Dihydroxy-prosta-5,13-dien-1-oic Acid Sodium Salt; Flolan. Grades: >99 %. CAS No. 61849-14-7. Molecular formula: C20H31O5Na. Mole weight: 374.45. | |
Furegrelate sodium salt Quick inquiry Where to buy Suppliers range | Furegrelate is a selective and potent inhibitor of thromboxane synthase with an IC50 value of 15 nM for human platelet microsomal thromboxane synthase. Synonyms: U-63557A; 5-(3-pyridinylmethyl)-2-benzofurancarboxylic acid, sodium salt. Grades: ≥99%. CAS No. 85666-17-7. Molecular formula: C15H10NO3·Na. Mole weight: 275.2. | |
ICI 185,282 Quick inquiry Where to buy Suppliers range | ICI 185,282 is a potent thromboxane receptor antagonist. Synonyms: ICI-185282; ICI 185282; ICI185282; 5-(Z)-7-(4-o-Hydroxyphenyl-2-trifluoromethyl-1,3 dioxan-cis-5-yl)heptenoic acid. CAS No. 106393-80-0. Molecular formula: C18H21F3O5. Mole weight: 374.36. | |
ICI 192,605 Quick inquiry Where to buy Suppliers range | ICI 192,605 is a potent thromboxane A2 receptor antagonist. It can reverse vasoconstriction induced by inhibition of NO production and inhibits platelet aggregation, which leads to an increase in TXA2 release. It also inhibits contractile responses to U 46619. Synonyms: ICI 192605 ; ICI192605; ICI-192605. (4Z)-rel-, 4(Z)-6-(2-o-chlorophenyl-4-o-hydroxyphenyl-1,3-dioxan-cis-5-yl) hexenoic acid; 4-Hexenoic acid, 6-[(2R,4R,5S)-2-(2-chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl]-; 4-(Z)-6-(2-o-Chlorophenyl-4-o-hydroxyphenyl-1,3-dioxan-cis-5-yl)hexenoic acid; (E)-6-[(2S,4S,5R)-2-(2-chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl]hex-4-enoic acid; rel-(4Z)-6-[(2R,4R,5S)-2-(2-Chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl]-4-hexenoic Acid. Grades: ≥98% by HPLC. CAS No. 117621-64-4. Molecular formula: C22H23ClO5. Mole weight: 402.87. | |
Ifetroban Quick inquiry Where to buy Suppliers range | Ifetroban is a selective Prostaglandin receptor and Thromboxane A2 receptor antagonist under the development of Bristol-Myers Squibb. Phase II clinical trials for the treatment of Asthma, Hepatorenal syndrome, Portal hypertension and Systemic scleroderma is on-going. Uses: Asthma; hepatorenal syndrome; portal hypertension; systemic scleroderma. Synonyms: Ifetroban; BMS 180291-02; BMS-180291; BMS180291; CHEMBL283100; BMS-180291;SCHEMBL9589119;3-[2-[[3-[4-(pentylcarbamoyl)-1,3-oxazol-2-yl]-7-oxabicyclo[2.2.1]heptan-2-yl]methyl]phenyl]propanoic acid. Grades: 98%. CAS No. 143443-90-7. Molecular formula: C25H32N2O5. Mole weight: 440.54. | |
I-SAP Quick inquiry Where to buy Suppliers range | I-SAP is a high affinity TP receptor antagonist. I-SAP binds to and induces platelet shape change, but not aggregation, with EC50 value of 9.7 nM. Synonyms: Iodophenyl sulfonyl amino pinane Thromboxane A2; Iodophenyl sulfonyl amino pinane TXA2; (Z)-7-[(1S,2S,3S,5R)-3-[(4-iodophenyl)sulfonylamino]-6,6-dimethyl-2-bicyclo[3.1.1]heptanyl]hept-5-enoic acid. Grades: ≥98%. CAS No. 133538-58-6. Molecular formula: C22H30INO4S. Mole weight: 531.4. | |
Ketoconazole (cis-1-Acetyl-4- [4- [ [2- (2, 4-dichlorophenyl) -2- (1H-imidazol-1-ylmethyl) -1, 3-dioxolan-4-yl] methoxy] phenyl] piperazine) Quick inquiry Where to buy Suppliers range | Inhibits cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo. Antimetastatic and antineoplastic activity. Orally active 5-lipoxygenase and thromboxane synthase inhibitor. Group: Biochemicals. Alternative Names: cis-1-Acetyl-4- [4- [ [2- (2, 4-dichlorophenyl) -2- (1H-imidazol-1-ylmethyl) -1, 3-dioxolan-4-yl] methoxy] phenyl] piperazine. Grades: Highly Purified. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
Ketoconazole-d8 (cis-1-Acetyl-4- [4- [ [2- (2, 4-dichlorophenyl) -2- (1H-imidazol-1-ylmethyl) -1, 3-dioxolan-4-yl] methoxy] phenyl] piperazine-d8) Quick inquiry Where to buy Suppliers range | Deuterated Ketoconazole, an inhibitor of cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo. Antimetastatic and antineoplastic activity. Orally active 5-lipoxygenase and thromboxane synthase inhibitor. Group: Biochemicals. Alternative Names: cis-1-Acetyl-4- [4- [ [2- (2, 4-dichlorophenyl) -2- (1H-imidazol-1-ylmethyl) -1, 3-dioxolan-4-yl] methoxy] phenyl] piperazine-d8. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
KF 13218 Quick inquiry Where to buy Suppliers range | KF 13218, a novel pyridobenzazepinone derivative, inhibited human and bovine platelet thromboxane synthase with IC50 values of 27 +/- 5.8 nmol/l (mean +/- S.E.M.) and 36 +/- 6.9 nmol/l, respectively. Synonyms: (6Z)-6-(6-methyl-5-oxopyrido[4,3-c][1]benzazepin-11-ylidene)hexanoic acid; 11-(5-carboxypentylidene)-6-methyl-5,11-dihydropyrido(4,3-c)(1)benzazepin-5(6H)-one; KF 13218; KF-13218; KF13218. CAS No. 127654-03-9. Molecular formula: C20H20N2O3. Mole weight: 336.38. | |
L-655,240 Quick inquiry Where to buy Suppliers range | L-655,240 is a potent and selective antagonist of thromboxane and prostaglandin endoperoxide receptor. It also blocks TP-mediated bronchoconstriction in vivo and platelet aggregation ex vivo. Synonyms: 3-(1-(4-Chlorobenzyl)-5-fluoro-3-methylindol-2-yl)-2,2-dimethylpropanoic acid. Grades: ≥98%. CAS No. 103253-15-2. Molecular formula: C21H21ClFNO2. Mole weight: 373.9. | |
L-670,596 Quick inquiry Where to buy Suppliers range | L-670,596 is a potent and selective thromboxane A2/prostaglandin endoperoxide receptor antagonist with IC50 value of 5.5 nM. It displays ALDH1A1 specific inhibitory activity. It inhibits human platelet aggregation and U-44069-induced contractions of guinea pig trachea in vitro. It also inhibits thromboxane-mediated endothelial cell death. It is orally active in vivo. Synonyms: L-670596; L 670596; L670596; (-)-6-8-Difluoro-2,3,4,9-tetrahydro-9-[[4-(methylsulfonyl)phenyl]methyl]-1H-carbazole-1-acetic acid; 2-[6,8-Difluoro-9-[(4-methylsulfonylphenyl)methyl]-1,2,3,4-tetrahydrocarbazol-1-yl]acetic acid. Grades: ≥98% by HPLC. CAS No. 121083-05-4. Molecular formula: C22H21F2NO4S. Mole weight: 433.47. | |
Linoleoyl coenzyme A Quick inquiry Where to buy Suppliers range | Linoleoyl coenzyme A acts as a vital molecular precursor in the polyunsaturated fatty acid biosynthesis process. These fatty acids are necessary in various biological frameworks. It's a driving force in the biosynthesis of crucial mediating factors like prostaglandins, leukotrienes, and thromboxanes which have a central role in managing inflammation and pain. Moreover, linoleoyl coenzyme A is a pivotal agent in the metabolism of drugs and toxins, making it a fundamental area of interest when researching toxicology, and drug discovery. Synonyms: cis,cis-9,12-Octadecadienoyl coenzyme A; (9Z,12Z)-Octadecadienoyl-CoA; Linoleoyl coenzyme A lithium salt. Grades: ≥ 92% (HPLC). CAS No. 6709-57-5. Molecular formula: C39H66N7O17P3S. Mole weight: 1029.97. | |
methyl (E)-3-(4-(methoxymethyl)phenyl)acrylate Quick inquiry Where to buy Suppliers range | methyl (E)-3-(4-(methoxymethyl)phenyl)acrylate is an impurity of Ozagrel, an antiplatelet drug that acts as a thromboxane A2 synthesis inhibitor. Synonyms: methyl (E)-3-(4-(methoxymethyl)phenyl)acrylate; AKOS020185360; 121379-29-1. CAS No. 121379-29-1. Molecular formula: C12H14O3. Mole weight: 206.24. | |
N,N-Diethylaminoethyl 2,2-diphenylvalerate hydrochloride (SKF-525A HCl) Quick inquiry Where to buy Suppliers range | Cytochrome P-459 inhibitor; blocks glibenclamide-sensitive K+ channels; inhibits neuronal nitric oxide synthetase; stimulates endothelial cell prostacyclin while inhibiting platelet thromboxane synthesis. Group: Biochemicals. Alternative Names: α-Phenyl-α-Propylbenzeneacetic Acid 2-(Diethylamino)ethyl Ester Hydrochloride; 2,2-Diphenylvaleric Acid 2-(Diethylamino)ethyl Ester Hydrochloride; 2-(Diethylamino)ethyl 2,2-Diphenylvalerate Hydrochloride; Proadifen Hydrochloride; RP 5171; SKF 525; U 5446. Grades: Highly Purified. CAS No. 62-68-0. Pack Sizes: 250mg, 500mg, 1g, 5g. Molecular Formula: C??H??ClNO?, Molecular Weight: 389.96. US Biological Life Sciences. | Worldwide |
ONO3708 Quick inquiry Where to buy Suppliers range | ONO3708 is a potent antagonist of the thromboxane A2/prostaglandin endoperoxide receptor in vitro and in vivo. It could play an important role in the pathogenesis of thrombosis and may be of therapeutic use in preventing cerebral vasospasm. It has therapeutic advantages in preventing thrombosis. Uses: Ono3708 may be of therapeutic use in preventing cerebral vasospasm. it has therapeutic advantages in preventing thrombosis. Synonyms: Ono3708; Ono-3708; Ono 3708;5-Heptenoic acid, 7-((1S,2S,3S,5R)-3-(((2R)-cyclopentylhydroxyacetyl)amino)-6,6-dimethylbicyclo(3.1.1)hept-2-yl)-, (5Z)-;(Z)-7-[(1R,3S,4S,5S)-3-[[(2R)-2-cyclopentyl-2-hydroxyacetyl]amino]-6,6-dimethyl-4-bicyclo[3.1.1]heptanyl]hept-5-enoic acid. Grades: >98 %. CAS No. 102191-05-9. Molecular formula: C23H37NO4. Mole weight: 391.55. | |
Ozagrel Quick inquiry Where to buy Suppliers range | Ozagrel is an antiplatelet agent working as a thromboxane A2 (TXA2) synthesis inhibitor. It has been a clinical objective for many years. lt is a 1-alkyl imidazole derivative that acts as a selective inhibitor of TXA2 with an IC50 of 11 nM. lt was selected as the best compound of highly selective inhibitors of TXA2 synthase. lt increased 6-keto-PGF1 alpha in various isolated cells and tissues. It blunted and delayed the decrease in cardiac output and maintained end-systolic pressure-diameter relation, +dp/dt, and lung lymph flow at baseline values. Uses: Ozagrel was selected as the best compound of highly selective inhibitors of txa2 synthase. lt increased 6-keto-pgf1 alpha in various isolated cells and tissues. Synonyms: OKY046; OKY 046; OKY-046; 2-Propenoic acid,3-[4-(1H-imidazol-1- ylmethyl)phenyl]-,(2E)-;(E)-p-(Imidazol-1-ylmethyl)cinnamic acid;(E)-3-[4-(imidazol-1-ylmethyl)phenyl]prop-2-enoic acid;(E)-3-[P-(imidazol-1-ylmethyl)phenyl]prop-2-enoic acid. Grades: >98%. CAS No. 82571-53-7. Molecular formula: C13H12N2O2. Mole weight: 228.25. | |
Ozagrel hydrochloride Quick inquiry Where to buy Suppliers range | Ozagrel hydrochloride is a thromboxane synthetase inhibitor with IC50 value of 4 nM. Uses: Enzyme inhibitors. Synonyms: (2E)-3-[4-(1H-Imidazol-1-ylmethyl)phenyl]-2-propenoic acid hydrochloride. Grades: ≥98% by HPLC. CAS No. 74003-18-2. Molecular formula: C13H12N2O2.HCl. Mole weight: 264.71. | |
Ozagrel Methyl Ester Quick inquiry Where to buy Suppliers range | Ozagrel Methyl Ester is an impurity of Ozagrel, an antiplatelet drug that acts as a thromboxane A2 synthesis inhibitor. Synonyms: methyl (E)-3-(4-((1H-imidazol-1-yl)methyl)phenyl)acrylate; (2E)-3-[4-(1H-imidazol-1-ylmethyl)phenyl]-methyl Ester 2-Propenoic Acid. CAS No. 956932-46-0. Molecular formula: C14H14N2O2. Mole weight: 242.27. | |
Ozagrel sodium Quick inquiry Where to buy Suppliers range | Ozagrel is a thromboxane A2 synthase inhibitor used as an antiplatelet agent. It reduces the risk of neurological impairment and the volume of brain damage. Synonyms: KCT-0809; Cataclot; Xanbo; (E)-3-[4-(imidazol-1-ylmethyl)phenyl]prop-2-enoate sodium. CAS No. 189224-26-8. Molecular formula: C13H11N2O2·Na. Mole weight: 250.23. | |
Parthenolide ((1aR-[1aR*, 4E, 7aS*, -10aS*, -10bR*])-2, 3-6, 7, 7a, 8, 10a, 10b-octahydro-1a, 5-dimethyl-8-methyleneoxireno[9, 10]cyclo deca[1,2-b]furan-9(1aH)-one) Quick inquiry Where to buy Suppliers range | An anti-inflammatory agent. Specifically inhibits activation of NF-kB by preventing the degradation of IkBa and IkBb. Inhibits activation of MAP kinase (MAPK/ERK) and generation of leukotriene B4 and thromboxane B2. Potent anticancer agent. Induces apoptosis in various cancer cell lines. Specifically inhibits histone deacetylase 1 (HDAC1) without affecting other class I/II HDACs. Group: Biochemicals. Grades: Highly Purified. CAS No. 20554-84-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
Picotamide Quick inquiry Where to buy Suppliers range | Picotamide is a dual inhibitor of thromboxane A2 (TXA2) receptors and TXA2 synthase. It is used as an antiplatelet drug. Picotamide has been demonstrated that reduces overall mortality in type 2 diabetic patients with associated peripheral arterial disease (PAD). Synonyms: 4-Methoxy-N,N'-bis(3-pyridinylmethyl)-1,3-benzenedicarboxamide. Grades: ≥98%. CAS No. 32828-81-2. Molecular formula: C21H20N4O3. Mole weight: 376.4. | |
Pimprinine (3-(2-Methyl-5-oxazolyl)-1H-indole, Antibiotic WS-30581C, NSC80793, 5-(3-Indoyl)-2-methyloxazole) Quick inquiry Where to buy Suppliers range | Indole alkaloid. Monoamine oxidase inhibitor (MAOI). Antiepileptic (anticonvulsant) compound. Inhibitor of platelet aggregation and thromboxane A2 synthesis. Weak antifungal and antituberculosis activity. Useful as lead structure for potent antifungal substances. Group: Biochemicals. Grades: Highly Purified. CAS No. 13640-26-1. Pack Sizes: 1mg, 5mg. Molecular Formula: C12H10N2O, Molecular Weight: 198.2. US Biological Life Sciences. | Worldwide |
Piperlongumine (Piplartine, 5,6-Dihydro-1-(1-oxo-3-trans-2-propenyl)-2-pyridinone) Quick inquiry Where to buy Suppliers range | Cytotoxic against tumor cell lines. Induces necrosis and apoptosis in cancer cells. Shows anti-platelet aggregation activity possibly by inhibition of cyclooxgenase activity and a decrease in thromboxane A2 formation. Shows significant anxiolytic and antidepressant activities. Promotes adipogenesis of 3T3-L1 cells. Induces in vivo and in vitro mutagenicity in eukaryotic models. Selectively kills cancer cells by targeting the stress response to ROS. Shows in vitro schistosomicidal activity. Group: Biochemicals. Alternative Names: Piplartine, 5,6-Dihydro-1-(1-oxo-3--trans-2-propenyl)-2-pyridinone. Grades: Highly Purified. CAS No. 20069-09-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
Prostaglandin H1 Quick inquiry Where to buy Suppliers range | Prostaglandin H1 (PGH1) is a COX metabolite of DGLA and is the precursor to all 1-series PGs and thromboxanes. PGH1 is a suicide inhibitor of platelet thromboxane synthase with Ki value of 28 μM. Synonyms: PGH1; 9S,11R-epidioxy-15S-hydroxy-13E-prostaenoic acid; 9alpha,11alpha-epidioxy-15(S)-hydroxy-13-trans-prostenoic acid. Grades: ≥95%. CAS No. 52589-22-7. Molecular formula: C20H34O5. Mole weight: 354.5. | |
R 59-022 Quick inquiry Where to buy Suppliers range | R 59-022 is a diacylglycerol (DAG) kinase inhibitor (IC50 = 2.8 μM) without affecting phosphodiesterase or phosphatidylinositol kinase, and potentiates the activity of protein kinase C by inhibiting diacylglycerol metabolism. R 59-022 also blocks vascular contraction induced by the thromboxane analog U-46619. At 10 μM, R 59-022 induces apoptosis in glioblastoma cells without being toxic to non-cancerous cells. Uses: Enzyme inhibitors. Synonyms: R59022; R-59022; R 59022; 6-[2-[4-[(4-Fluorophenyl)phenylmethylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one; Diacylglycerol Kinase Inhibitor I. Grades: ≥98% by HPLC. CAS No. 93076-89-2. Molecular formula: C27H26FN3OS. Mole weight: 459.58. | |
Ramatroban Quick inquiry Where to buy Suppliers range | Ramatroban is a thromboxane A(2) (TxA(2)) antagonist marketed for allergic rhinitis. Synonyms: Ramatroban; Bay u 3406; Bay u-3405; BAY u3405; EN 137774. Grades: >98%. CAS No. 116649-85-5. Molecular formula: C21H21FN2O4S. Mole weight: 416.47. | |
Ramatroban Quick inquiry Where to buy Suppliers range | A thromboxane receptor antagonist for use in the treatment of coronary artery disease. Group: Biochemicals. Alternative Names: (3R) -3-[[ (4-Fluorophenyl) sulfonyl]amino]-1, 2, 3, 4-tetrahydro-9H-carbazole-9-propanoic Acid; BAY-u 3405; Baynas. Grades: Highly Purified. CAS No. 116649-85-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Ridogrel Quick inquiry Where to buy Suppliers range | Ridogrel is a thromboxane synthase inhibitor used for the prevention of systemic thrombo-embolism. It is also a receptor antagonist that may be used as an adjunctive agent to thrombolytic therapy in acute myocardial infarction. It was developed by Xian Janssen and was terminated in clinic phase 3 trials. Uses: Ridogrel is used for the prevention of systemic thrombo-embolism. it also may be used as an adjunctive agent to thrombolytic therapy in acute myocardial infarction. Synonyms: Ridogrel, R 68070; R-68070; R68070; R 70416; R-70416; R70416; 5-[[Pyridin-3-yl-[3- (trifluoromethyl) phenyl]methylidene]amino]oxypenta noic acid; 5-[[ (E) - (3-Pyridinyl) [3- (trifluoromethyl) phenyl]methylene]aminooxy]valeric acid; 5-[[[ (E) -α - (Pyridine-3-yl) -3- (trifluoromethyl) benzylidene]amino]oxy]valeric acid;R-68070;Pentanoic acid, 5-[[ (E) -[3-pyridinyl[3- (trifluoromethyl) phenyl]methylene]amino]oxy]-. Grades: 95%. CAS No. 110140-89-1. Molecular formula: C18H17F3N2O3. Mole weight: 366.33. | |
SB 203580 hydrochloride Quick inquiry Where to buy Suppliers range | SB 203580 hydrochloride is a water-soluble form of the potent MAP kinase inhibitor SB 203580 with IC50 values of 50 and 500 nM for SAPK2a/p38 and SAPK2b/p38β2, respectively. It was shown to inhibit interleukin-2-induced T cell proliferation, cyclooxygenase-1 and -2, and thromboxane synthase. Synonyms: 4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazole hydrochloride. Grades: >98%. CAS No. 869185-85-3. Molecular formula: C21H17FN3OSCl. Mole weight: 413.9. | |
Seratrodast Quick inquiry Where to buy Suppliers range | Seratrodast is a potent and selective thromboxane A2 receptor (TP) antagonist used primarily in the treatment of asthma. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: (+/-)-7-(3,5,6-Trimethyl-1,4-benzoquinon-2-yl)-7-phenylheptanoic Acid; AA-2414; Benzeneheptanoic acid, ζ-(2,4,5-trimethyl-3,6-dioxo-1,4-cyclohexadien-1-yl)-; Benzeneheptanoic acid, ζ-(2,4,5-trimethyl-3,6-dioxo-1,4-cyclohexadien-1-yl)-, (±)-; ζ-(2,4,5-Trimethyl-3,6-dioxo-1,4-cyclohexadien-1-yl)benzeneheptanoic acid; (±)-2,4,5-Trimethyl-3,6-dioxo-ζ-phenyl-1,4-cyclohexadiene-1-heptanoic acid; 7-(3,5,6-Trimethyl-1,4-benzoquinon-2-yl)-7-phenylheptanoic acid; 7-Phenyl-7-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dien-1-yl)heptanoic acid; A 73001; AA 2414; AA2414; Abbott 73001; ABT 001; Bronica; Seratodrast. Grades: >98%. CAS No. 112665-43-7. Molecular formula: C22H26O4. Mole weight: 354.44. | |
Seratrodast ((±)-7-(3,5,6-Trimethyl-1,4-benzoquinon-2-yl)-7-phenylheptanoic Acid, AA-2414,. Abbott 73001, Bronica) Quick inquiry Where to buy Suppliers range | Thromboxane A2-receptor antagonist. Antiasthmatic. Group: Biochemicals. Alternative Names: (±)-7-(3,5,6-Trimethyl-1,4-benzoquinon-2-yl)-7-phenylheptanoic Acid; AA-2414; Abbott 73001; Bronica. Grades: Highly Purified. CAS No. 112665-43-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
SKF-525A, Hydrochloride (Proadifen, HCl, a-Phenyl-a-propylbenzeneacetic Acid 2-[Diethylamino]ethyl Ester, HCl) Quick inquiry Where to buy Suppliers range | Cytochrome P-459 inhibitor; blocks glibenclamide-sensitive K+ channels; inhibits neuronal nitric oxide synthetase; stimulates endothelial cell prostacyclin while inhibiting platelet thromboxane synthesis. Group: Biochemicals. Alternative Names: Proadifen, HCl, a-Phenyl-a-propylbenzeneacetic Acid 2-[Diethylamino]ethyl Ester, HCl. Grades: Highly Purified. Pack Sizes: 2g. US Biological Life Sciences. | Worldwide |
Sulfinpyrazone Quick inquiry Where to buy Suppliers range | Sulfinpyrazone is a uricosuric medication used to treat gout. It inhibits uric acid reabsorption in kidney proximal tubules. It can also used to reduce platelet aggregation by inhibiting degranulation of platelets which reduces the release of ADP and thromboxane. It was developed by Novartis and has been listed. Uses: Sulfinpyrazone is a uricosuric medication used to treat gout. Synonyms: G-28315; G28315; G 28315; Anturane; Sulfinpyrazon; Anturan; Diphenylpyrazone; Anturanil; 1,2-Diphenyl-4-(2-(phenylsulfinyl)ethyl)pyrazolidine-3,5-dione; NSC 75925. Grades: 98%. CAS No. 57-96-5. Molecular formula: C23H20N2O3S. Mole weight: 404.48. | |
Terutroban Quick inquiry Where to buy Suppliers range | Terutroban is a potent, orally active antagonist of the thromboxane/prostaglandin A2(TP) receptor (IC50 = 16.4 nM). In guinea pigs it also inhibits U 46619 induced increase pressure in the bronchi. Synonyms: Terutroban; S 18886; S-18886; S18886; 3-[(6R)-6-[(4-chlorophenyl)sulfonylamino]-2-methyl-5,6,7,8-tetrahydronaphthalen-1-yl]propanoic acid3-((6-amino-(4-chlorobenzenesulfonyl)-2-methyl-5,6,7,8-tetrahydronapht)-1-yl)propionic acid3-((6R)-6-(((4-chlorophenyl)sulfonyl)amino)-2-methyl-5,6,7,8 te. CAS No. 165538-40-9. Molecular formula: C20H22ClNO4S. Mole weight: 407.91. | |
Triflusal Quick inquiry Where to buy Suppliers range | Triflusal irreversibly inhibits the production of thromboxane-B2 in platelets by acetylating cycloxygenase-1. Uses: Platelet aggregation inhibitors. Synonyms: UR1501; UR 1501; UR-1501. Grades: >98%. CAS No. 322-79-2. Molecular formula: C10H7F3O4. Mole weight: 248.16. | |
U 46619 Quick inquiry Where to buy Suppliers range | U 46619 is a PGH2 (TXA2) analog that is reported to be a potent and stable thromboxane A2 (TP) receptor agonist (EC50 = 0.035 μM). U 46619 has been shown to stimulate TP receptor-mediated, but not other prostaglandin receptor-mediated responses in various in vitro preparations. U 46619 also activates ERK-1 and ERK-2 in HEK 293 cells expressing TPα and TPβ receptors. Synonyms: U46619, U-46619, U 46619; (5Z)-7-[(1R,4S,5S,6R)-6-[(1E,3S)-3-Hydroxy-1-octenyl]-2-oxabicyclo[2.2.1]hept-5-yl]-5-heptenoic acid. Grades: ≥98% by HPLC. CAS No. 56985-40-1. Molecular formula: C21H34O4. Mole weight: 350.5. | |
U-51605 Quick inquiry Where to buy Suppliers range | U-51605 is a stable analog of the endoperoxide prostaglandin H2 (PGH2). U-51605 is an inhibitor of both prostacyclin (PGI) and thromboxane (TX) synthases, as well as a partial agonist at TP receptors. Synonyms: U 51605; U51605; 7-(6-Oct-1-enyl-2,3-diazabicyclo[2.2.1]hept-2-en-5-yl)hept-5-enoic acid. Grades: ≥98%. CAS No. 64192-56-9. Molecular formula: C20H32N2O2. Mole weight: 332.5. | |
UK 34787 Quick inquiry Where to buy Suppliers range | UK 34787 is a thromboxane inhibitor,but no detailed information has been published yet. Synonyms: UK 34787, UK-34787, UK34787; 3-((1H-imidazol-1-yl)methyl)-2-isopropyl-1H-indole. Grades: 98%. CAS No. 72818-36-1. Molecular formula: C15H17N3. Mole weight: 239.32. |