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UK-1 is a cytotoxic metabolite from Streptomyces sp. 517-02 and exerts a wide spectrum of potent anticancer activities. UK-1 also inhibits HCV replication. Uses: Designed for use in research and industrial production. Additional or Alternative Names: UK 1. Product Category: Inhibitors. Appearance: White to off-white solid. CAS No. 151271-53-3. Molecular formula: C22H14N2O5. Mole weight: 386.362. Canonical SMILES: O=C(C1=C2N=C(C3=C4N=C(C5=CC=CC=C5O)OC4=CC=C3)OC2=CC=C1)OC. Product ID: ACM151271533. Alfa Chemistry ISO 9001:2015 Certified. Categories: Uk 1997 election.
UK-1
UK-1, a benzoxazol derivative, has been found to be a Streptomyces metabolite that could exhibit anticancer activity and topoisomerase II restraination activity. Synonyms: UK 1, UK-1, UK1; [2,4'-Bibenzoxazole]-4-carboxylicacid, 2'-(2-hydroxyphenyl)-, methyl ester; ACMC-20n661; CTK4C6968; ZINC598610. Grades: 98%. CAS No. 151271-53-3. Molecular formula: C22H14N2O5. Mole weight: 386.36.
UK-1745
UK-1745, an indole derivative, has been found to be a Calcium channel antagonist that was once studied in the treatment of arrhythmias as well as heart failure. Synonyms: 2-Aminomethyl-2,3,7,8-tetrahydro-2,3,5,8,8-pentamethyl-6H-furo(2,3-e)indole-7-one hydrochloride; CTK0H6059; UK 1745; UK1745; UK-1745. Grades: 98%. CAS No. 170684-14-7. Molecular formula: C16H23ClN2O2. Mole weight: 310.82.
UK-1 (Antibiotic)
Antibiotic UK-1 is an unusual bis-benzoxazole metabolite isolated from a species of Streptomyces. It exhibits good antitumor activity but is devoid of antimicrobial activity. Antibiotic UK-1 acts as a magnesium ion-dependent DNA binding agent and inhibitor of human topoisomerase II. Group: Biochemicals. Grades: Highly Purified. CAS No. 151271-53-3. Pack Sizes: 1mg. US Biological Life Sciences.
Brimonidine D-Tartrate is an alpha2 receptor agonist. It is a drug used to treat glaucoma and acts via decreasing aqueous humor synthesis. Group: Biochemicals. Alternative Names: 5-Bromo-N-(4,5-dihydro-1H-imidazol-d4-2-yl)-6-quinoxalinamine D-Tartrate; 5-Bromo-6-(2-imidazolin-d4-2-ylamino)quinoxaline; UK-14304-18-d4; AGN-190342-LF-d4; Alphagan-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
It is an a 2 receptor agonist. It is a drug used to treat glaucoma. It acts via decreasing aqueous humor synthesis. Group: Biochemicals. Alternative Names: 5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-6-quinoxalinamine L-Tartrate; 5-Bromo-6-(2-imidazolin-2-ylamino)quinoxaline; UK-14304-18; AGN-190342-LF; Alphagan. Grades: Highly Purified. CAS No. 70359-46-5. Pack Sizes: 100mg. US Biological Life Sciences.
Labeled Vorizonazole, used as an antifungal. An Ergosterol Biosynthesis inhibitor. Group: Biochemicals. Alternative Names: (aR,bS)-a-(2,4-Difluorophenyl)-5-fluoro-b-methyl-d3-a-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol; UK-109496-d3. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Voriconazole Impurity 10 (UK-115191)
One of the impurities of Voriconazole, which has been found to be an ergosterol biosynthesis inhibitor and could be used as an antifungal agent. Molecular formula: C10H7F2N3O. Mole weight: 223.18.
AJI-9561
AJI-9561 is a benzoxazole derivative produced by Streptomyces sp. AJ9561. It has cytotoxic activity with IC50 of 0.88 μmol/L and 1.63 μmol/L for Jorkat and P388 cells, respectively. Its mechanism of action is the same as that of UK-1, which can inhibit DNA topoisomerase U. Synonyms: (2,4'-Bibenzoxazole)-4-carboxylic acid, 2'-(2-hydroxy-6-methylphenyl)-. CAS No. 339300-34-4. Molecular formula: C22H14N2O5. Mole weight: 386.36.
Brimonidine
α2-Adrenoceptor agonist. Antiglaucoma. Group: Biochemicals. Alternative Names: 5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-6-quinoxalinamine; 5-Bromo-6-(2-imidazolin-2-ylamino)quinoxaline; Bromoxidine;AGN-190342; UK-14304. Grades: Highly Purified. CAS No. 59803-98-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Brimonidine
Brimonidine is α2-Adrenoceptor agonist. It is a drug used as eye drops to treat open-angle glaucoma or ocular hypertension. It acts via decreasing synthesis of aqueous humor, and increasing the amount that drains from the eye through uveoscleral outflow. Uses: α2-adrenoceptor agonist. antiglaucoma. Synonyms: UK 14,304; UK14,304; UK-14,304; UK14304; Brimonidine; AGN 190342; AGN-190342; AGN1903425-bromo-n-(4,5-dihydro-1h-imidazol-2-yl)-6-quinoxalinamin. Grades: ≥95%. CAS No. 59803-98-4. Molecular formula: C11H10BrN5. Mole weight: 292.13.
Brimonidine L-tartrate
Brimonidine L-tartrate. Group: Biochemicals. Alternative Names: 5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-6-quinoxalinamine L-tartrate; 5-Bromo-6-(2-imidazolin-2-ylamino)quinoxaline; UK-14304-18. Grades: Highly Purified. CAS No. 70359-46-5. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C15H16BrN5O6. US Biological Life Sciences.
Worldwide
Brimonidine Tartrate
Brimonidine Tartrate is a highly selective α-adrenergic receptor agonist with EC50 of 0.45 nM for the α2A adrenoreceptor, and used to treat open-angle glaucoma or ocular hypertension. Synonyms: Brimonidine L-Tartrate; 5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-6-quinoxalinamine L-Tartrate; 5-Bromo-6-(2-imidazolin-2-ylamino)quinoxaline; UK-14304-18; AGN-190342-LF. Grades: >98%. CAS No. 70359-46-5. Molecular formula: C15H16BrN5O6. Mole weight: 442.22.
Eletriptan
Eletriptan is Serotonin 1D receptor agonist originated by Pfizer. It is a second generation triptan drug. It is used as an abortive medication, blocking a migraine attack which is already in progress. Eletriptan was approved by the FDA for the acute treatment of migraine with or without aura in adults in 2002. Uses: Menstrual migraine; migraine. Synonyms: 3-[[(2R)-1-Methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethyl]-1H-indole; (R)-5-[2-(Benzenesulfonyl)ethyl]-3-[(N-methylpyrrolidin-2-yl)methyl]-1H-indole; Eletriptan; UK 116044; UK-116,044; UK-116,044-04 [as hydrobromide]; UNII-22QOO9B8KI; Relpax free amine. Grades: 98%. CAS No. 143322-58-1. Molecular formula: C22H26N2O2S. Mole weight: 382.52.
Eletriptan HBr
Eletriptan induces concentration-dependent contractions of meningeal artery, coronary artery, and saphenous vein. The potency of Eletriptan is higher in meningeal artery than in coronary artery (86-fold) or saphenous vein (66-fold). Synonyms: Eletriptan Hydrobromide; CHEBI:61176; M41W832TA3; UNII-M41W832TA3; eletriptan hydrobromide; Relpax; UK 166,044; UK 166044; UK-166,044; UK-166044. Grades: >98%. CAS No. 177834-92-3. Molecular formula: C22H26N2O2S.HBr. Mole weight: 463.43.
Eletriptan hydrobromide
Eletriptan hydrobromide (Eletriptan HBr) is a 5-HT 1B and 5-HT 1D receptor agonist with antimigraine activity, with K i of 0.92 nM and 3.14 nM, respectively [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Eletriptan HBr; UK-116044 hydrobromide. CAS No. 177834-92-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0010.
N-Desmethyl Sildenafil
N-Desmethyl Sildenafil (Desmethylsildenafil) is a major metabolite of Sildenafil. Sildenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Desmethylsildenafil; UK-103,320. CAS No. 139755-82-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117605.
Triadimenol
Triadimenol is a agricultural fungicide that is systemically active against powdery mildews and rusts of grains. lt is a systemic fungicide with a broad spectrum. It inhibits the ergosterol - and gibberellin - biosynthesis. Uses: Triadimenol is a agricultural fungicide that is systemically active against powdery mildews and rusts of grains. Synonyms: UK 199; UK-199; UK199; Baytan;Bayfidan;Spinnaker;Summit;1-(4-Chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-ol;UK-199;UK199;1,2,4-Triazole-1-ethanol, beta-(4-chlorophenoxy)-alpha-(1,1-dimethylethyl)-;Beta-(4-chlorophenoxy)-alpha-(1,1-dimethylethyl)-1H-1,2,4-triazole-. Grades: 98%. CAS No. 55219-65-3. Molecular formula: C14H18ClN3O2. Mole weight: 295.76.
Voriconazole
An ergosterol biosynthesis inhibitor. Anti-fungal; sterol 14α-demethylase inhibitor. Group: Biochemicals. Alternative Names: (aR,bS)-a-(2,4-Difluorophenyl)-5-fluoro-b-methyl-a-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol; UK-109496. Grades: Highly Purified. CAS No. 137234-62-9. Pack Sizes: 1g, 5g. Molecular Formula: C16H14F3N5O, Molecular Weight: 349.31. US Biological Life Sciences.
Worldwide
Voriconazole
Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: UK-109496. CAS No. 137234-62-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-76200.
(±)-Voriconazole
(±)-Voriconazole ((±)-UK-109496) is a relative configuration of Voriconazole (HY-76200). Voriconazole is an antifungal agent [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-UK-109496. CAS No. 188416-29-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W337569.
Voriconazole-d3
Voriconazole-d 3 is the deuterium labeled Voriconazole. Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: UK-109496-d3. CAS No. 1217661-14-7. Pack Sizes: 500 μg; 1 mg. Product ID: HY-76200S.
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