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| Product | Description | |
|---|---|---|
| 16:0 EPC chloride | 16:0 EPC chloride, a P-O-ethyl derivative, is a saturated cationic lipid. 16:0 EPC chloride can serve as a DNA and RNA transfecting agent. 16:0 EPC chloride can be used as a co-adjuvant for preparing vaccines and promote drug delivery [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 328250-18-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144016. |  |
| 2-Hydroxy Imiquimod | 1-(4-Amino-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol, has been shown to activate a toll-like receptor 7/8 Independent Cytokine, which can be used in the design of immunomodulating agents for use as vaccine adjuvants and anticancer treatments. Group: Biochemicals. Grades: Highly Purified. CAS No. 112668-45-8. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C14H16N4O. US Biological Life Sciences. |  Worldwide |
| 3'-CPR II CPG | 3'-CPR II CPG, a vital tool in molecular biology, is renowned for unraveling the elusive role of Toll-like receptor 9 (TLR9) in shaping the immune system. In the domain of immunotherapy, the adjuvant supplements DNA vaccines and jumpstarts immune responses to eradicate cancer and infections. Dive into the intriguing world of 3'-CPR II CPG as its therapeutic potential has undergone rigorous scrutiny in pre-clinical and clinical trials. Synonyms: 3-(4,4'-Dimethoxytrityloxy)-2,2-(dicarboxymethylamido)propyl-1-O-succinoyl-long chain alkylamino-CPG. Mole weight: 79.98. |  |
| 3'-QD-3 CPG 1000 | 3'-QD-3 CPG 1000 is a synthetic oligonucleotide used as an immune modulator in the treatment of cancer and infectious diseases. It enhances the activation of immune cells to increase anti-tumor and anti-viral responses. It is also used as an adjuvant therapy with vaccine treatments for various types of cancer. | |
| 4A-MPLA | 4A-MPLA, the synthetic antigen-adjuvant, is employed in vaccines that bolster immune responses to infectious agents and cancers. The toll-like receptor 4 (TLR4) is vigorously activated by this powerful agonist, which, when given with other adjuvants, augments vaccine effectiveness during vaccination programs intended to combat bacterial and viral infections, including tuberculosis, influenza, and meningitis. Synonyms: Monophosphoryl Tetra-acyl Lipid A. Grades: 98%. CAS No. 2260669-09-6. Molecular formula: C68H132N3O19P. Mole weight: 1326.76. | |
| 7DW8-5 | 7DW8-5, a novel glycolipid, an analog of α-galactosylceramide (α-GalCer), is an immunostimulate iNKT agonist and a vaccine adjuvant that can harness and amplify the immunotherapeutic potential of NKT cells to treat certain microbial infections such as malaria and HIV. Studies have shown that the adjuvant effect of 7DW8-5 wasmediated by CD1dmolecules. Synonyms: [(2S,3S,4R)-1-O-(α-D-galactopyranosyl)-N-(11-(4-fluorophenyl)undecanoyl)-2-amino-1,3,4-octadecanetriol)]; N-[(2S,3S,4R)-3,4-dihydroxy-1-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoctadecan-2-yl]-11-(4-fluorophenyl)undecanamide; 11-(4-Fluorophenyl)-N-[(2s,3s,4r)-1-(Alpha-D-Galactopyranosyloxy)-3,4-Dihydroxyoctadecan-2-Yl]undecanamide; CHEBI:86489; 7DW8-5; 7DW. CAS No. 1056025-00-3. Molecular formula: C41H72FNO9. Mole weight: 742. | |
| Adjuvant Peptide | Adjuvant Peptide is an immunomodulatory factor that can be used as a vaccine adjuvant to enhance immune response. It inhibits HIV replication in CD4+H9 lymphocytes. Uses: Adjuvants, immunologic. Synonyms: D-α-Glutamine, N-(N-acetylmuramoyl)-L-alanyl-; D-α-Glutamine, N2-[N-(N-acetylmuramoyl)-L-alanyl]-; N-(N-Acetylmuramoyl)-L-alanyl-D-α-glutamine; Acetylmuramoyl-L-alanyl-D-isoglutamine; MDP; MDP-D; Muramoyl dipeptide; N-(Acetylmuramoyl)-L-alanyl-D-isoglutamine; N-(Acetylmuramoyl)alanyl-D-isoglutamine; N-Acetylmuramoyl dipeptide; N-Acetylmuramoyl-L-alanine-D-isoGln; N-Acetylmuramoylalanyl-D-isoglutamine; (4R,5R,7R,10S,13R)-13-carbamoyl-4-formyl-7,10-dimethyl-2,8,11-trioxo-5-((1R,2R)-1,2,3-trihydroxypropyl)-6-oxa-3,9,12-triazahexadecan-16-oic acid; N-Ac-Mur-Ala-D-Glu-NH2; N-Acetylmuramyl-L-Ala-D-Glu-NH2; Muramyl dipeptide. Grades: ≥95%. CAS No. 53678-77-6. Molecular formula: C19H32N4O11. Mole weight: 492.48. | |
| Aluminium phosphate | Aluminium phosphate occurs in nature as the mineral, berlinite. Also, it occurs in nature in minerals, amblygonite, [NaAl(PO4)(OH)]; augelite, [Al2(PO4)(OH)3]; lazulite, [(Mg,Fe)Al2(PO4)2(OH)2]; variscite [(Al,Fe3+)(PO4) 2H2O]; and wavellite, [Al3(OH)3 (PO4)2 5H2O]. It is used as flux for ceramics; as cement in combination with calcium sulfate and sodium silicate; and in the manufacture of special glasses. It is also used in dried gel and therapeutically as an antacid. Product ID: PE-0677. Molecular formula: AlPO4. Mole weight: 121.9529. Category: Antacid; vaccine adjuvant. Product Keywords: Vaccine Adjuvants; PE-0677; Aluminium phosphate. Chemical Name: Aluminium phosphate. Grade: Pharmaceutical grade. Administration route: Accepted for use in human and veterinary vaccines. Dosage Form: Accepted for use in human and veterinary vaccines. Stability and Storage Conditions: Aluminum phosphate adjuvant is stable for at least 2 years when stored at 4-308°C in well-sealed inert containers. It must not be allowed to freeze as the hydrated colloid structure will be irreversibly damaged. Source and Preparation: Aluminum phosphate adjuvant is formed by the reaction of a solution of aluminum chloride and phosphoric acid with alkali hydroxide. Applications: Aluminum Phosphate is an odorless, white crystalline solid which is often used in liquid or gel form. It is used in ceramics, dental cements, cosmetics, paints, paper an |  |
| Aluminum Hydroxide | Aluminum Hydroxide is an orally active main form of aluminum used as adjuvant. Aluminum hydroxide-based adjuvant researches include the repository effect, pro-phagocytic effect, and activation of the pro-inflammatory NLRP3 pathway. Aluminum Hydroxide also acts as adjuvant to compensate low inherent immunogenicity of subunit vaccines [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 21645-51-2. Pack Sizes: 500 mg; 1 g. Product ID: HY-B1521. | |
| Aluminum Hydroxide Adjuvant | Aluminum hydroxide adjuvant is a white hydrogel that sediments slowly and forms a clear supernatant. Synonyms: Alhydrogel; aluminii hydroxidum hydricum ad adsorptionem; aluminium hydroxide adjuvant; aluminium oxyhydroxide; poorly crystalline boehmite; pseudoboehmite; Rehydragel. CAS No. 21645-51-2. Product ID: PE0377. Molecular formula: AlO(OH). Mole weight: 59.99. Category: Adsorbents. Product Keywords: Pharmaceutical Excipients; Excipients for Solid Dosage Form; Filler Excipients; Absorbent; Aluminum Hydroxide Adjuvant; PE0377; 5QB0T2IUN0; 21645-51-2; 21645-51-2. UNII: 5QB0T2IUN0. Chemical Name: Aluminum oxyhydroxide. Grade: Pharmceutical Excipients. Stability and Storage Conditions: Aluminum hydroxide adjuvant is stable when stored at 4-30°C in well-sealed inert containers. It must not be allowed to freeze as the hydrated colloid structure will be irreversibly damaged. Applications: Aluminum hydroxide adjuvant is used in parenteral human and veterinary vaccines. Safety: Aluminum hydroxide adjuvant is intended for use in parenteral vaccines and is generally regarded as nontoxic. | |
| Aluminum Phosphate Adjuvant | Aluminum phosphate adjuvant is a white hydrogel that sediments slowly and forms a clear supernatant. Synonyms: Adju-Phos; aluminum hydroxyphosphate; aluminium hydroxyphosphate; Rehydraphos. Product ID: PE0379. Molecular formula: Al(OH)x(PO4)y. Category: Adsorbents. Product Keywords: Pharmaceutical Excipients; Excipients for Solid Dosage Form; Filler Excipients; Absorbent; Aluminum Phosphate Adjuvant; PE0379. Chemical Name: Aluminum phosphate. Grade: Pharmceutical Excipients. Stability and Storage Conditions: Aluminum phosphate adjuvant is stable fwhen stored at 4-30°C in well-sealed inert containers. It must not be allowed to freeze as the hydrated colloid structure will be irreversibly damaged. Applications: Aluminum phosphate adjuvant is used in parenteral human and veterinary vaccines. Safety: Aluminum phosphate adjuvant is intended for use in parenteral vaccines and is generally regarded as safe. It may cause mild irritation, dryness, and dermatitis on skin contact. It may also cause redness, conjunctivitis, and short-term mild irritation on eye contact. Ingestion of large amounts of aluminum phosphate adjuvant may cause respiratory irritation with nausea, vomiting, and constipation. Inhalation is unlikely, although the dried product may cause respiratory irritation and cough. Type I hypersensitivity reactions following parenteral administration have also been reported. | |
| Amino-PEG7-alcohol | Amino-PEG7-alcohol (CAS# 1425973-14-3) is a reagent used in pharmaceutical preparations such as the preparation of a water-soluble cancer vaccine adjuvant. Synonyms: 2- [2- [2- [2- [2- [2- (2-aminoethoxy) ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethanol; 2- [2- [2- [2- [2- [2- (2-aminoethoxy) ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethanol. Grades: >97%. CAS No. 1425973-14-3. Molecular formula: C14H31NO7. Mole weight: 325.40. | |
| Amorphous aluminum hydroxyphosphate sulfate | Amorphous aluminum hydroxyphosphate sulfate (AAHS) is an aluminum-containing adjuvant produced by Merck & Company (Rahway, NJ, USA), and is used in several commercial vaccines, including Recombivax, Gardasil, and Vaxelis. Synonyms: AAHS; aluminum hydroxyphosphate sulfate. CAS No. 150828-31-2. Molecular formula: AlHO9PS-3. Mole weight: 235.03. | |
| b-D-Glucan - from Yeast (Saccharomyces Cerevisiae) | b-D-Glucan - from Yeast (Saccharomyces Cerevisiae): b-D-Glucan, derived from Saccharomyces cerevisiae yeast, is a natural compound utilized in the biomedical industry. Widely recognized for its immunomodulatory properties, b-D-Glucan is extensively employed as an adjuvant in vaccines and therapeutics for enhancing immune responses. Uses: Adjuvants, immunologic. Synonyms: 1,3-b-D-Glucan; b-1,3-D-Glucan. CAS No. 9012-72-0. Molecular formula: (C6H10O5)n. Mole weight: 472.4. | |
| Calcium Phosphate | Calcium phosphate was used as an adjuvant in France in diphtheria, tetanus, pertussis, and poliomyelitis vaccines. Synonyms: Phosphoric acid, calcium salt (1:x); Phosphoric acid, calcium salt; Budal MW 500; Calcium phosphate; Crodax DP 30; Dikal 21; Dynafos; E 341; Halox 430; HAP 05NP; HAP 60NPG; KDV 15u; LF-CP-ZA; Man-Gill 51504; Mecahl P; Mekaru P; Osteon GBC0305; Toppufuro K. Grades: 95%. CAS No. 10103-46-5. Molecular formula: Ca.xH3O4P. Mole weight: 97.99 (free acid). | |
| dI-CPG 1000 | dI-CPG 1000, a powerful synthetic immunostimulatory oligonucleotide that serves to activate the natural immune system. Its unique ability to act as a Toll-like receptor 9 (TLR9) agonist initiates the production of an array of cytokines and chemokines, which in turn create a domino effect that stimulates immune responses effectively. Its extensive application in cancer immunotherapy as an adjuvant and also as a vaccine adjuvant against a vast range of infectious diseases amplifies its importance in the scientific community. Synonyms: 5'-Dimethoxytrityl-2'-deoxyInosine, 3'-succinoyl-long chain alkylamino-CPG 1000. Mole weight: 314.19. | |
| Difucosyllacto-N-hexaose (b) | Difucosyllacto-N-hexaose (b) is a compound widely employed sector, used for studying a plethora of afflictions, including cancer and viral infections. As an adjuvant, this compound exerts its influence by amplifying the immune response, thus rendering it indispensable in the realm of drug discovery for immunotherapy and vaccine formulation. Synonyms: DFLNH (b); Cluster Lewis x-Lewis a octasaccharide branched. Molecular formula: C52H88N2O39. Mole weight: 1365.25. | |
| Dried aluminum hydroxide gel,United States Pharmacopeia (USP) Reference Standard | Dried aluminum hydroxide gel is a commonly used antacid with significant compound adhesion and release activity. Dried aluminum hydroxide gel can effectively neutralize gastric acid and relieve stomach discomfort. Dried aluminum hydroxide gel is also often used as an adjuvant in vaccines to enhance immune response. Dried aluminum hydroxide gel can improve the stability and bioavailability of compounds in preparations. Uses: Scientific research. Group: Signaling pathways. CAS No. 21645-51-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W116335A. | |
| Gardiquimod | Immune response modifier. Antiviral and antitumor compound. Selective ligand for human or mouse Toll-like receptor 7 (TLR7). Induces the activation of NF-kappaB in HEK 293 cells expressing TLR7 at 0.1ug/ml. 10 times more active than Imiquimod. At high concentrations (3ug/ml) slightly activates TLR8. Shows adjuvant activity to increase the effectiveness of vaccines. Group: Biochemicals. Alternative Names: 1- (4-Amino-2-ethylamino methyl imidazo [4, 5-c] quinolin-1-yl) -2- methyl propan-2-ol, 4-Amino-2-[(ethylamino)methyl]-?,?-dimethyl-1H-Imidazo[4,5-c]quinoline-1-ethanol. Grades: Highly Purified. CAS No. 1020412-43-4. Pack Sizes: 5mg, 25mg. Molecular Formula: C??H??N?O. US Biological Life Sciences. | Worldwide |
| Imiquimod Impurity 1 (S-26704) | used in the design of immunomodulating agents for use as vaccine adjuvants and anticancer treatments. Synonyms: 2-Hydroxy Imiquimod; 4-Amino-α,α-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol; R 842; R 842 (pharmaceutical); 1-(4-Amino-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol; 2-Hydroxy Imiquimod. Grades: > 95%. CAS No. 112668-45-8. Molecular formula: C14H16N4O. Mole weight: 256.31. | |
| Inulin | Inulin (Inulin and sodium chloride) is a starch found in the tubers and roots of many plants, classified as a fructosan. Inulin is used as an adjuvant to enhance vaccine efficacy against influenza, hepatitis B, West Nile virus, Japanese encephalitis, human immunodeficiency virus, SARS, and anthrax. Synonyms: β-d-[2?1] poly(fructo-furanosyl) α-d-glucose; Poly-b-(2-1)-fructofuranose; Polyfructose; a-D-glucopyranosyl-[b-D-fructofuranosyl](n-1)-D-fructofuranosides; GpyFn; Advax; Advax D; Agave Inulin; Alant starch; Alantin; Beneo; CBP Inulin; Dahlin; Fibruline; Fibrulose; Inulin Fib97; LV 110; Oliggo-Fiber F 97; P95 FOS; Prebiofeed; Raftifeed IPE; Raftifeed IPS; Raftiline; Sinantrin; Synantherin; Ticaloid LC-CSR 2. Grades: 90%. CAS No. 9005-80-5. Molecular formula: C6nH10n+2O5n+1. | |
| KIN1148 | KIN1148, a small-molecule IRF3 agonist, associates with and activates recombinant RIG-I protein in cell-free assays. KIN1148 is a novel influenza vaccine adjuvant found to enhance flu vaccine efficacy. Synonyms: KIN-1148; KIN 1148; KIN1148; N-([1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)naphthalene-2-carboxamide. Grades: ≥98% (HPLC). CAS No. 1428729-56-9. Molecular formula: C19H11N3OS2. Mole weight: 361.44. | |
| Loxoribine | Guanosine analog derivatized at position N7 and C8. Very potent immunostimulatory compound that increases cytokine production. Antitumor and antiviral activity compound. Potent and selective synthetic ligand for Toll-like receptor 7 (TLR7). Co-incubation with thymidine homopolymer oligodeoxynucleotides (ODN) redirected the stimulatory effect of loxoribine away from TLR7 toward TLR8. Induces autophagy and autophagy-induced cell death in Caco-2 cells. Shows adjuvant activity to increase the effectiveness of vaccines. Group: Biochemicals. Alternative Names: 7-Allyl-8-oxoguanosine; RWJ 21757, 7-Allyl-2-amino-9-(3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-7,9-dihydro-1H-purine-6,8-dione. Grades: Highly Purified. CAS No. 121288-39-9. Pack Sizes: 5mg, 25mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences. | Worldwide |
| Monophosphoryl 3-deacyl Lipid A ammonium salt | Monophosphoryl 3-deacyl Lipid A ammonium salt is a remarkable biomedical innovation, aiding in studying infectious diseases. As an exquisitely crafted immunostimulating adjuvant, it is widely used for developing vaccines. Synonyms: 3D-PHAD®. Grades: >99%. CAS No. 1699735-79-9. Molecular formula: C82H158N3O20P. Mole weight: 1537.11. | |
| Monophosphoryl Lipid A | Monophosphoryl Lipid A is a toll-like receptor 4 agonist with potential immunostimulatory activity, which is commonly used as a vaccine adjuvant. Synonyms: MPLA (PHAD®); phosphorylated hexaacyl disaccharide; Glycopyranoside Lipid A. Grades: > 99%. CAS No. 1246298-63-4. Molecular formula: C96H184N3O22P. Mole weight: 1763.47. | |
| NGcGM3 (Bovine Spleen) | NGcGM3 (Bovine Spleen), derived from bovine spleen tissue, is a formidable immunotherapeutic agent, leveraging its immunomodulatory properties in the fight against breast, lung, and colon cancer. In preclinical models, it has demonstrated remarkable efficacy in facilitating immune responses against the malignant cells and thus is considered a potential game-changer in the treatment of these dreaded diseases. In addition to its direct antitumor effects, NGcGM3 (Bovine Spleen) has shown promise as a vaccine adjuvant, elevating the potency and efficacy of cancer vaccines by providing additional augmentation to the body's immune response. Synonyms: NGcGM3 Ganglioside (spleen). Grades: >99%. CAS No. 2260670-78-6. Molecular formula: C65H121N3O22. Mole weight: 1296.66. | |
| Poly(I:C) | Poly(I:C) is an immunostimulant used in the form of sodium salts to simulate viral infections. Poly(I:C) is structurally similar to double-stranded RNA, found in some viruses, and is a ''natural'' stimulator of TLR3. Therefore, Poly(I:C) can be considered a synthetic analog of double-stranded RNA and is a common tool for scientific research in the immune system. Poly(I:C) is a vaccine adjuvant that increases vaccine immunogenicity, especially in formulations that target dendritic cells. Synonyms: Poly I:C; Polyinosinic-polycytidylic acid [Poly(I:C)]; Poly I C; Poly I-C; Poly(rI).Poly(rC); Polyinosinic-Polycytidylic Acid; 5'-Inosinic acid, homopolymer, complex with 5'-cytidylic acid homopolymer (1:1); 5'-Cytidylic acid, homopolymer, complex with 5'-inosinic acid homopolymer (1:1); 5'-Cytidylic acid, polymers, complex with 5'-inosinic acid polymers (1:1); 5'-Inosinic acid, polymers, complex with 5'-cytidylic acid polymers (1:1); 5'-Inosinic acid homopolymer-5'-cytidylic acid homopolymer complex; NSC 120949; NSC 123233; NSC 128576; Poly I:C; Poly(C).poly(I); Poly(C:I); Poly(cytidylic acid)-poly(inosinic acid); Poly(I)-poly(C); Poly(I).poly(C) complex; Poly(rI)-poly(rC); Poly(rI):poly(rC); Poly(rI:rC); Polyinosinate-polycytidylate complex; Polyinosinate:polycytidylate; Polyinosine-polycytidylic acid; Polyinosinic acid:polycytidylic acid; Polyinosinic acid:polycytidylic acid complex; Polyinosinic-polycytidylic acid; Polyinosinic-polycytidylic acid complex; Polyribocytidylic acid-polyriboinosinic acid complex. CAS No. 24939-03-5. Molecular formula: (C10H13N4O8P)x (C9H14N3O8P)x. Mole weight: 671.4. | |
| Polyinosinic-polycytidylic acid | Polyinosinic-polycytidylic acid (Poly(I:C)) is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gene I (RIG-I)-like receptors ( RIG-I and MDA5 ). Polyinosinic-polycytidylic acid can be used as a vaccine adjuvant to enhance innate and adaptive immune responses, and to alter the tumor microenvironment. Polyinosinic-polycytidylic acid can directly trigger cancer cells to undergo apoptosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Poly(I:C). CAS No. 24939-03-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107202. | |
| Polyinosinic-polycytidylic acid sodium | Polyinosinic-polycytidylic acid (Poly(I:C)) sodium is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gene I (RIG-I)-like receptors ( RIG-I and MDA5 ). Polyinosinic-polycytidylic acid sodium can be used as a vaccine adjuvant to enhance innate and adaptive immune responses, and to alter the tumor microenvironment. Polyinosinic-polycytidylic acid sodium can directly trigger cancer cells to undergo apoptosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Poly(I:C) sodium. CAS No. 42424-50-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135748. | |
| QS-21 | QS-21, an immunostimulatory saponin, could be used as a potent vaccine adjuvant. QS-21 stimulates Th2 humoral and Th1 cell-mediated immune responses through action on antigen presenting cells (APCs) and T cells. QS-21 can activate the NLRP3 inflammasome with subsequent release of caspase-1 dependent cytokines, IL-1β and IL-18 [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Stimulon. CAS No. 141256-04-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-101092. | |
| QS-21 | QS-21 is a natural triterpenoid saponin extracted from the soap bark tree. It has the potential use as an immunologic adjuvant in vaccine to enhance their efficacy. Synonyms: Saponin QA 21V1; QS-21. Grades: 90%. CAS No. 141256-04-4. Molecular formula: C92H148O46. Mole weight: 1990.13. | |
| Resiquimod (R-848, S 28463) | Immune response modifier. Potent antitumor and antiviral compound. Stimulates antibody secretion and cytokine production. Used as adjuvant to increase the effectiveness of vaccines. Potent and selective synthetic ligand for Toll-like receptor 7 (TLR7) in mouse and for TLR7 and TLR8 in human. Activates immune cells via the TLR7/TLR8 MyD88-dependent signaling pathway and leads to the induction of NF-kappaB. NLRP3/NALP3 inflammasome activator, independent of TLRs and RIG-I. Upregulator of the opioid growth factor receptor. Used in the treatment of skin lesions such as herpes simplex virus. Group: Biochemicals. Alternative Names: 1-[4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol; 4-Amino-2- (ethoxymethyl) -1- (2-hydroxyisobutyl) imidazo[4, 5-c]quinoline; 4-Amino-2-ethoxymethyl-α,α-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol; R 848; Resiquimod; S 28463. Grades: Highly Purified. CAS No. 144875-48-9. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C??H??N?O?, Molecular Weight: 314.4. US Biological Life Sciences. | Worldwide |
| RS 09 | RS09 is a LPS peptide mimic serves as a candidate to be considered as a new class of TLR4 agonist adjuvant. RS09 increases antibody production in a vaccine setting [1]. Uses: Scientific research. Group: Peptides. CAS No. 1449566-36-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P1439. | |
| RS09 2TFA | RS09 2TFA, a TLR4 agonist, is an adjuvant that promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. RS09 increases antibody production in the vaccine environment. Synonyms: H-Ala-Pro-Pro-His-Ala-Leu-Ser-OH.2TFA; L-alanyl-L-prolyl-L-prolyl-L-histidyl-L-alanyl-L-leucyl-L-serine trifluoroacetic acid; RS 09 2TFA. Grades: ≥95%. Molecular formula: C35H51F6N9O13. Mole weight: 919.82. | |
| Thymalfasin | Thymalfasin is an immunomodulating agent indicated as an adjuvant for influenza vaccine in elderly patients. Synonyms: Thymosin α1. Grades: 98%. CAS No. 69440-99-9. Molecular formula: C129H215N33O55. Mole weight: 3108.31. | |
| Trehalose-6,6'-dibehenate | Trehalose-6,6'-dibehenate is a bioactive glycolipid and an analog of mycobacterial cord factor. Trehalose-6,6'-dibehenate is considered less toxic and an efficient vaccine adjuvant for tuberculosis. Synonyms: 22:0 Trehalose; D-(+)-trehalose 6,6'-dibehenate; 6,6'-didocosanoyl-α,α'-trehalose; TDB. Grades: >99%. CAS No. 66758-35-8. Molecular formula: C56H106O13. Mole weight: 987.43. | |
| c-di-IMP | c-diIMP is an analogue of c-diAMP and c-diGMP, the bacterial second messengers, which is potentially used as an adjuvant for mucosal vaccination. Synonyms: Cyclic diinosine monophosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 79940-41-3. Molecular formula: C20H22N8O14P2 (free acid). Mole weight: 660.4 (free acid). | |
| Chitosan | Chitosan is a deacetylated derivative of chitin. Chitosan is a polysaccharide present in the exoskeleton of a variety of crustaceans and cell walls of fungi. It can be used in the medical field and cosmetics manufacturing. In addition to its role in drug delivery, chitosan can also act as an adjuvant due to its immune-stimulating activity. Chitosan stimulates the immune system by activating the NLRP3 inflammasome, which produces potent IL-1b. When tested in an experimental model of vaccination, chitosan elicits a balanced Th1/Th2 response. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Deacetylated chitin; Poly(D-glucosamine); Poly-b-(1,4)-2-Amino-2-deoxy-D-glucose; 2-Amino-2-deoxy-(1,4)-b-D-glucopyranan; deacetylchitin; b-1,4-poly-D-glucosamine; poly-D-glucosamine; poly-(1,4-b-D-glucopyranosamine). Grades: DAC degree?90%+. CAS No. 9012-76-4. Molecular formula: [C7H15NO4]n. Mole weight: 60-120 kDa. | |
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