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| Product | Description | |
|---|---|---|
| Vinblastine | Vinblastine, an inhibitor of nAChR, is a natural alkaloid isolated from the plant Vinca rosea Linn. It binds to tubulin and inhibits microtubule formation, leading to disruption of mitotic spindle assembly and arrest of tumor cells in the M-phase of the cell cycle. It may also interfere with the metabolism of amino acids, cyclic AMP, and glutathione. It is used to treat malignant lymphoma. Uses: Antitumor. Synonyms: [3aR-[3aa, 4b, 5b, 5ab, 9(3R*, 5S*, 7R*, 9S*), 10bR*, 13aa]]-Methyl 4-(acetyloxy)-3a-ethyl-9-[5-ethyl-1,4,5,6,7,8,9,10-octahydro-5-hydroxy-9-(methoxycarbonyl)-2H-3,7-methanoazacycloundecino[5,4-b]indol-9-yl]-3a,4,5,5a,6,11,12,13a-octahydro-5-hydroxy-8-methoxy-6-methyl-1H-indolizino[8,1-cd]carbazole-5-carboxylate; 1H-Indolizino[8,1-cd]carbazole, vincaleukoblastine deriv.; 1H-Indolizino(8,1-cd)carbazole-5-carboxylic acid, 4-(acetyloxy)-3a-ethyl-9-(5-ethyl-1,4,5,6,7,8,9,10-octahydro-5-hydroxy-9-(methoxycarbonyl)-2H-3,7-methanoazacycloundecino(5,4-b)indol-9-yl)-3a,4,5,5a,6,11,12,13a-octahydro-5-hydroxy-8-methoxy-6-methyl-, methyl ester, (3aR-(3aα, 4β, 5β, 5aβ, 9(3R*, 5S*, 7R*, 9S*), 10bR*, 13aα))-; Rozevin; (+)-Vinblastine; Vincaleukoblastine. Grades: >98%. CAS No. 865-21-4. Molecular formula: C46H58N4O9. Mole weight: 810.97. |  |
| Vinblastine | Vinblastine. Group: Biochemicals. Grades: Plant Grade. CAS No. 865-21-4. Pack Sizes: 20mg. US Biological Life Sciences. |  Worldwide |
| Vinblastine-d3 | Labeled Vinblastine. Antitumor alkaloid isolated from periwinkle, Vinca rosea Linn., Apocynaceae; inhibits microtubule assembly. An antineoplastic. Group: Biochemicals. Alternative Names: Vincaleukoblastine. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Vinblastine-d5-methylchloride Iodide | Vinblastine-d5-methylchloride Iodide is the labeled analogue of Vinblastine-methylchloride Iodide (V314010), an adduct of Vinblastine (V314000), an antitumor alkaloid isolated from periwinkle, Vinca rosea Linn., Apocynaceae; inhibits microtubule assembly. An antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C47H55D5ClIN4O9, Molecular Weight: 992.39. US Biological Life Sciences. | Worldwide |
| Vinblastine Impurity A | An impurity of Vinblastine. Vinblastine, isolated from Vinca rosea Linn., is an antitumor agent that is used for the treatment of kinds of cancers, including Hodgkin's lymphoma, non-small cell lung cancer, bladder cancer, brain cancer, melanoma, and testicular cancer. It binds tubulin and inhibits the assembly of microtubules. Synonyms: (5S,7S,9S)-9-((3aR,3a1R,4R,5S,5aR,10bR)-4-acetoxy-3a-ethyl-5-hydroxy-8-methoxy-5-(methoxycarbonyl)-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazol-9-yl)-3-(chloromethyl)-5-ethyl-5-hydroxy-9-(methoxycarbonyl)-1,2,3,4,5,6,7,8,9,10-dec. Molecular formula: C47H60ClN4O9.Cl. Mole weight: 895.93. | |
| Vinblastine Impurity B | An impurity of Vinblastine. Vinblastine, isolated from Vinca rosea Linn., is an antitumor agent that is used for the treatment of kinds of cancers, including Hodgkin's lymphoma, non-small cell lung cancer, bladder cancer, brain cancer, melanoma, and testicular cancer. It binds tubulin and inhibits the assembly of microtubules. Synonyms: (5S,7S,9S)-9-((3aR,3a1R,4R,5S,5aR,10bR)-4-acetoxy-3a-ethyl-5-hydroxy-8-methoxy-5-(methoxycarbonyl)-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazol-9-yl)-5-ethyl-5-hydroxy-9-(methoxycarbonyl)-1,2,3,4,5,6,7,8,9,10-decahydro-3,7-methan. CAS No. 61936-68-3. Molecular formula: C46H58N4O10. Mole weight: 827. | |
| Vinblastine Impurity C | An impurity of Vinblastine. Vinblastine, isolated from Vinca rosea Linn., is an antitumor agent that is used for the treatment of kinds of cancers, including Hodgkin's lymphoma, non-small cell lung cancer, bladder cancer, brain cancer, melanoma, and testicular cancer. It binds tubulin and inhibits the assembly of microtubules. Synonyms: N-Desmethyl Vinblastine; 1-Demethyl-vincaleukoblastine; N-Deformylleurocristine; N-Deformylvincristine. CAS No. 18172-50-4. Molecular formula: C45H56N4O9. Mole weight: 796.97. | |
| Vinblastine Impurity D | An impurity of Vinblastine. Vinblastine, isolated from Vinca rosea Linn., is an antitumor agent that is used for the treatment of kinds of cancers, including Hodgkin's lymphoma, non-small cell lung cancer, bladder cancer, brain cancer, melanoma, and testicular cancer. It binds tubulin and inhibits the assembly of microtubules. Synonyms: 19'-Oxovinblastine; (3aR,3a1R,4R,5S,5aR,10bR)-Methyl 4-Acetoxy-3a-ethyl-9-((3R,5S,7S,9S)-5-ethyl-5-hydroxy-9-(methoxycarbonyl)-15-oxo-2,4,5,6,7,8,9,10-octahydro-1H-3,7-methano[1]azacycloundecino[5,4-b]indol-9-yl)-5-hydroxy-8-methoxy-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate. Molecular formula: C46H56N4O10. Mole weight: 824.98. | |
| Vinblastine Impurity E | An impurity of Vinblastine. Vinblastine, isolated from Vinca rosea Linn., is an antitumor agent that is used for the treatment of kinds of cancers, including Hodgkin's lymphoma, non-small cell lung cancer, bladder cancer, brain cancer, melanoma, and testicular cancer. It binds tubulin and inhibits the assembly of microtubules. Synonyms: Methyl (3aR,4R,5S,5aR,10bR,13aR)-3a-ethyl-9-[(5S,7R,9S)-5-ethyl-5-hydroxy-9-(methoxycarbonyl)-1,4,5,6,7,8,9,10-octahydro-2H-3,7-methanoazacycloundecino[5,4-b]indol-9-yl]-4,5-dihydroxy-8-methoxy-6-methyl-3a,4,5,5a,6,11,12,13aoctahydro-1H-indolizino[8,1-cd]. Molecular formula: C44H56N4O8. Mole weight: 768.96. | |
| Vinblastine Impurity F | An impurity of Vinblastine. Vinblastine, isolated from Vinca rosea Linn., is an antitumor agent that is used for the treatment of kinds of cancers, including Hodgkin's lymphoma, non-small cell lung cancer, bladder cancer, brain cancer, melanoma, and testicular cancer. It binds tubulin and inhibits the assembly of microtubules. Synonyms: Leurosine; (1aS,11S,13R,13aR)-methyl 11-((3aR,3a1R,4R,5S,5aR,10bR)-4-acetoxy-3a-ethyl-5-hydroxy-8-methoxy-5-(methoxycarbonyl)-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazol-9-yl)-1a-ethyl-2,4,5,10,11,12,13,13a-octahydro-1aH-3,13-me. Molecular formula: C46H56N4O9. Mole weight: 808.98. | |
| Vinblastine Impurity G | An impurity of Vinblastine. Vinblastine, isolated from Vinca rosea Linn., is an antitumor agent that is used for the treatment of kinds of cancers, including Hodgkin's lymphoma, non-small cell lung cancer, bladder cancer, brain cancer, melanoma, and testicular cancer. It binds tubulin and inhibits the assembly of microtubules. Synonyms: (1aS,11S,13R,13aR)-methyl 11-((3aR,3a1R,4R,5S,5aR,10bR)-4-acetoxy-3a-ethyl-5-hydroxy-8-methoxy-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazol-9-yl)-1a-ethyl-2,4,5,10,11,12,13,13a-octahydro-1aH-3,13-methanooxireno[2',3':9,10][1]azac. Molecular formula: C44H56N4O7. Mole weight: 752.96. | |
| Vinblastine Impurity H | An impurity of Vinblastine. Vinblastine, isolated from Vinca rosea Linn., is an antitumor agent that is used for the treatment of kinds of cancers, including Hodgkin's lymphoma, non-small cell lung cancer, bladder cancer, brain cancer, melanoma, and testicular cancer. It binds tubulin and inhibits the assembly of microtubules. Synonyms: (3aS,3a1R,4R,5R,5aR,10bR)-methyl 4-acetoxy-3a-ethyl-9-((5S,7S,9S)-5-ethyl-5-hydroxy-9-(methoxycarbonyl)-2,4,5,6,7,8,9,10-octahydro-1H-3,7-methano[1]azacycloundecino[5,4-b]indol-9-yl)-8-methoxy-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-3H-3,5-epoxyindolizin. Molecular formula: C46H56N4O9. Mole weight: 808.98. | |
| Vinblastine Impurity J | Vinblastine Impurity J is an adduct of Vinblastine. Vinblastine, isolated from Vinca rosea Linn., is an antitumor agent that is used for the treatment of kinds of cancers, including Hodgkin's lymphoma, non-small cell lung cancer, bladder cancer, brain cancer, melanoma, and testicular cancer. It binds tubulin and inhibits the assembly of microtubules. Synonyms: Vinblastine Methiodide; 6'-Methylvincaleukoblastinium Iodide; 1H-Indolizino[8,1-cd]carbazole Vincaleukoblastinium Deriv.; 2H-3,7-Methanoazacycloundecino[5,4-b]indole Vincaleukoblastinium Deriv.; (3R,5S,7S,9S)-9-((3aR,3a1R,4R,5S,5aR,10bR)-4-Acetoxy-3a-ethyl-5-hydroxy-8-methoxy-5-(methoxycarbonyl)-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazol-9-yl)-5-ethyl-5-hydroxy-9-(methoxycarbonyl)-3-methyl-1,2,3,4,5,6,7,8,9,10-decahydro-3,7-methano[1]azacycloundecino[5,4-b]indol-3-ium Iodide. CAS No. 61988-79-2. Molecular formula: C47H61N4O9.I. Mole weight: 952.93. | |
| Vinblastine Impurity K | Cas No. 71486-22-1. | |
| Vinblastine Impurity M | An impurity of Vinblastine. Vinblastine, isolated from Vinca rosea Linn., is an antitumor agent that is used for the treatment of kinds of cancers, including Hodgkin's lymphoma, non-small cell lung cancer, bladder cancer, brain cancer, melanoma, and testicular cancer. It binds tubulin and inhibits the assembly of microtubules. Synonyms: (1bS,1b1R,2R,3S,3aR,8bR)-methyl 2-acetoxy-1b-ethyl-7-((5S,7S,9S)-5-ethyl-5-hydroxy-9-(methoxycarbonyl)-15-oxo-2,4,5,6,7,8,9,10-octahydro-1H-3,7-methano[1]azacycloundecino[5,4-b]indol-9-yl)-3-hydroxy-6-methoxy-4-methyl-1b,1b1,2,3,3a,4,9,10,12,12a-decahydro. Molecular formula: C46H56N4O11. Mole weight: 840.98. | |
| Vinblastine sulfate | Vinblastine sulfate, also called cellblastin, derived from C. roseus, as a microtubule disrupter and antineoplastic agent, it binds tubulin and disrupts microtubule assembly and proper formation of the mitotic spindle, which leads to the assembly of microtubules and causing M phase-specific cell cycle arrest. Uses: Anticancer. Synonyms: cell pharm Brand of Vinblastine Sulfate; cellblastin; EG Labo Brand of Vinblastine Sulfate; Faulding Brand of Vinblastine Sulfate; Gastrozepin Brand of Vinblastine Sulfate; Gry Brand of Vinblastine Sulfate; Hexal Brand of Vinblastine Sulfate; Lemblastine; Lemery Brand of Vinblastine Sulfate; Lilly Brand of Vinblastine Sulfate; Sulfate, Vinblastine; Velban; Velbe; Vinblastin Hexal; Vinblastina Lilly; Vinblastine; Vinblastine Sulfate; Vinblastinsulfat-Gry; Vincaleukoblastine; Vinblastine sulfate; 143-67-9; C46H58N4O9H2SO4. Grades: >98%. CAS No. 143-67-9. Molecular formula: C46H58N4O9.H2SO4. Mole weight: 909.06. | |
| Vinblastine sulfate | Vinblastine sulfate. Group: Biochemicals. Alternative Names: Vincaleukoblastine. Grades: Highly Purified. CAS No. 143-67-9. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C46H60N4O13S. US Biological Life Sciences. | Worldwide |
| Vinblastine sulfate | Vinblastine sulfate is a cytotoxic alkaloid used against various cancer types. Vinblastine sulfate inhibits the formation of microtubule and suppresses nAChR with an IC50 of 8.9 μM. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (3S)-3-Phenylisoserine hydrochloride. Product Category: Inhibitors. Appearance: White powder. CAS No. 143-67-9. Molecular formula: C46H60N4O13S. Mole weight: 909.05. Purity: 0.98. IUPACName: Methyl (1R,9R,10S,11R,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15S,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate;sulfuric acid. Canonical SMILES: CC[C@@]1(C[C@@H]2C[C@@](C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)[C@]78CCN9[C@H]7[C@@](C=CC9)([C@H]([C@@]([C@@H]8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O.OS(=O)(=O)O. Product ID: ACM143679. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Vinblastine sulfate | Vinblastine sulfate is a cytotoxic alkaloid used against various cancer types. Vinblastine sulfate inhibits the formation of microtubule and suppresses nAChR with an IC 50 of 8.9 μM. Uses: Scientific research. Group: Natural products. Alternative Names: Vincaleukoblastine sulfate salt. CAS No. 143-67-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13780. |  |
| Vinblastine Sulfate (29060-LE, Exal, Velban, Velbe,) | An antineoplastic. Group: Biochemicals. Alternative Names: 29060-LE, Exal, Velban, Velbe. Grades: Highly Purified. CAS No. 143-67-9. Pack Sizes: 20mg. US Biological Life Sciences. | Worldwide |
| Vinblastine Sulphate USP | S-adenosyl-L-homocysteine hydrolase (SAHH) inhibitor, hypocholesterolemic activity. Grades: USP. CAS No. 143-67-9. Product ID: 8-04410. Molecular formula: C46H58N4O9.H2SO4. Mole weight: 909.06. |  |
| 4-Desacetyl Vinblastine Methosulfate | A pro-drug of Vinblastine. Group: Biochemicals. Alternative Names: O4-Deacetyl-vincaleukoblastine Methosulfate; 4-Deacetylvinblastine Methosulfate; Deacetylvinblastine Methosulfate. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Anhydro Vinblastine-d3 Disulfate Salt | Anhydrovinblastine. Group: Biochemicals. Alternative Names: 3', 4'-Dide hydro-4'-deoxyvincaleukoblastin e-d3 Disulfate Salt; (+)-Anhydrovinblastine-d3 Disulfate Salt; 3',4'-Anhydrovinblastine-d3 Disulfate Salt; 3',4'-Dehydroisoleurosine-d3 Disulfate Salt; 3',4'-Dehydrovinblastine-d3 Disulfate Salt; 3',4'-Didehydroisoleurosine-d3 Disulfate Salt; An hydrovincaleukoblas tine-d3 Disulfate Salt; F 81097-d3 Disulfate Salt. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Anhydro Vinblastine Disulfate Salt | Anhydrovinblastine. Group: Biochemicals. Alternative Names: 3', 4'-Dide hydro-4'-deoxyvincaleukoblastin e Disulfate Salt; (+)-Anhydrovinblastine Disulfate Salt; 3',4'-Anhydrovinblastine Disulfate Salt; 3',4'-Dehydroisoleurosine Disulfate Salt; 3',4'-Dehydrovinblastine Disulfate Salt; 3',4'-Didehydroisoleurosine Disulfate Salt; An hydrovincaleukoblas tine Disulfate Salt; F 81097 Disulfate Salt. Grades: Highly Purified. CAS No. 81165-17-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| N-Desmethyl vinblastine | N-Desmethyl vinblastine. Group: Biochemicals. Alternative Names: 1-Demethyl-vincaleukoblastine; N-Deformylleurocristine; N-Deformylvincristine. Grades: Highly Purified. CAS No. 18172-50-4. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C45H56N4O9. US Biological Life Sciences. | Worldwide |
| N-Desmethyl Vinblastine | N-Desmethyl Vinblastine. Uses: For analytical and research use. Group: Impurity standards. CAS No. 18172-50-4. Molecular Formula: C45H56N4O9. Mole Weight: 796.95. Catalog: APS18172504. SMILES: CC[C@]1 (O)C[C@@H]2CN (CCc3c ([nH]c4ccccc34)[C@@] (C2) (C (=O)OC)c5cc6c (N[C@H]7[C@] (O) ([C@H] (OC (=O)C)[C@]8 (CC)C=CCN9CC[C@]67[C@H]89)C (=O)OC)cc5OC)C1. Format: Neat. |  |
| N-Desmethyl Vinblastine, protocol with the exact weight | N-Desmethyl Vinblastine, protocol with the exact weight. Uses: For analytical and research use. Group: Impurity standards. CAS No. 18172-50-4. Pack Sizes: 10MG. Molecular Formula: C45H56N4O9. Mole Weight: 796.95. Catalog: APS18172504A. SMILES: CC[C@]1 (O)C[C@@H]2CN (CCc3c ([nH]c4ccccc34)[C@@] (C2) (C (=O)OC)c5cc6c (N[C@H]7[C@] (O) ([C@H] (OC (=O)C)[C@]8 (CC)C=CCN9CC[C@]67[C@H]89)C (=O)OC)cc5OC)C1. Format: Neat. | |
| Vincristine EP Impurity H (vinblastine) | Vincristine EP Impurity H (vinblastine). Uses: For analytical and research use. Group: Impurity standards. CAS No. 865-21-4. Molecular Formula: C46H58N4O9. Mole Weight: 810.99. Catalog: APB865214. | |
| Vincristine EP Impurity H (vinblastine) Sulfate | Vincristine EP Impurity H (vinblastine) Sulfate. Uses: For analytical and research use. Group: Impurity standards. CAS No. 143-67-9. Molecular Formula: C46H60N4O13S. Mole Weight: 909.06. Catalog: APB143679. | |
| 19'-Oxovincaleukoblastine-d3 Sulfate | 19'-Oxovincaleukoblastine-d3 Sulfate is the labeled analogue of 19'-Oxovincaleukoblastine Sulfate (O867210), a metabolite of Vinblastine Sulfate (V314000), an antitumor alkaloid isolated from periwinkle, Vinca rosea Linn., Apocynaceae; inhibits microtubule assembly. An antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C46H53D3N4O10. x(H2O4S), Molecular Weight: 827.989808. US Biological Life Sciences. | Worldwide |
| 19'-Oxovincaleukoblastine Sulfate | 19'-Oxovincaleukoblastine Sulfate is a metabolite of Vinblastine Sulfate (V314000), an antitumor alkaloid isolated from periwinkle, Vinca rosea Linn., Apocynaceae; inhibits microtubule assembly. An antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C46H56N4O10. x(H2O4S), Molecular Weight: 824.969807999999. US Biological Life Sciences. | Worldwide |
| 3',4'-Anhydro Vincristine Ditartrate | A derivative of Vinblastine, an antitumor alkaloid. Group: Biochemicals. Alternative Names: 3',4'-Didehydro-4'-deoxy-22-oxo-vincaleukoblastine Ditartrate; 3',4'-Anhydroleurocristine Ditartrate; 3',4'-Anhydrovincristine Ditartrate; Anhydroleurocristine Ditartrate; Anhydrovincristine Ditartrate. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| ALB-109564 | ALB 109564(a) is a semi-synthetic derivative of the vinka alkaloid vinblastine with potential antineoplastic activity. Tubulin inhibitor ALB 109564(a) binds to tubulin monomers and inhibits microtubule formation, resulting in disruption of mitotic spindle assembly and arrest of tumor cells in the G2/M phase of the cell cycle. Synonyms: ALB-109564; ALB 109564; ALB109564; ALB 109564(a); Vincaleukoblastine, 12'-(methylthio)-, hydrochloride (1:2). CAS No. 854756-74-4. Molecular formula: C47H60N4O9S. Mole weight: 857.07. | |
| Anhydrovinblastin | immunosuppression. Uses: Immunosuppression. Synonyms: ANHYDROVINBLASTINE; Vinblastineanhydrous; Vincaleukoblastine, 3',4'-didehydro-4'-deoxy-; C11641; 3',4'-anhydrovinblastine; 3,4-ANHYDROVINBLASTINE,95%; ANHYDROVINBLASTIN; 3',4'-Didehydro-4'-deoxyvincaleukoblastine. Grades: >98%. CAS No. 38390-45-3. Molecular formula: C46H56N4O8. Mole weight: 792.96. | |
| Ansamitocin P3 | Ansamitocin P-3 is a metabolite of Ansamitocin which is a new maytansinoid antitumor antibiotic. Fungal metabolite with antineoplastic, antimitotic activity. Binds to tubulin and inhibits vinblastine-induced spiral formation. Group: Biochemicals. Alternative Names: 3-O-De[2-(acetylmethylamino)-1-oxopropyl]-3-O-(1-oxobutyl)-maytansine; 4, 24-Dioxa-9, 22-diazatetracyclo[19. 3. 1. 110, 14. 03, 5]hexacosane, maytansine deriv.; Ansamitocin P 3; Antibiotic C 15003P3; Maytansinol Butyrate. Grades: Purified. CAS No. 66547-09-9. Pack Sizes: 25mg, 50mg, 100mg, 250mg. Molecular Formula: C32H43CIN2O9, Molecular Weight: 635.14. US Biological Life Sciences. | Worldwide |
| Catharanthine-d3 | Isotope labeled precursor of Vinblastine-type alkaloids. Group: Biochemicals. Alternative Names: (2α,5 β,6α,18 β)-3,4-Didehydro-ibogamine-18-carboxylic Acid Methyl-d3 Ester; (+)-3,4-Didehydrocoronaridine-d3; (+)-Catharanthine-d3; Catharanthin-d3. Grades: Highly Purified. CAS No. 133146-02-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Catharanthine Tartrate | Precursor of Vinblastine-type alkaloids. Group: Biochemicals. Alternative Names: (2α,5 β,6α,18 β)-3,4-Didehydro-ibogamine-18-carboxylic Acid Methyl Ester Tartrate ; (+)-3,4-Didehydrocoronaridine Tartrate; (+)-Catharanthine Tartrate; Catharanthin Tartrate. Grades: Highly Purified. CAS No. 4168-17-6. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Cevipabulin | Cevipabulin (TTI-237) is an oral, microtubule-active antitumor compound and inhibits the binding of [ 3 H] vinblastine to tubulin, with an IC 50 of 18-40 nM for cytotoxicity in human tumor cell line [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TTI-237. CAS No. 849550-05-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14949. | |
| cis-Diamineplatinum(II) dichloride | cis-Diamineplatinum(II) dichloride. Uses: Cisplatin is a cytostatic agent and it is used to treat various cancer types, including cancer of ovary, testis, lung, head, neck, bladder, neuroblastoma, and nephroblastoma, and hodgkin's disease and non-hodgkin lymphoma.cddp, also referred to as cisplatinum or cisplatin, is a yellow powder and has found widespread use a chemotherapeutic agent.cisplatin, combined with bleomycin and vinblastine or etoposide, produces cures in most patients with metastatic testicular cancer or germ cell cancer of the ovary. cisplatin also shows some activity against carcinomas of the head and neck, bladder, cervix, prostate, and lung. Group: Salt. Alternative Names: cis-Dichlorodiammine platinum(II). CAS No. 15663-27-1. Molecular formula: 300.05. Mole weight: Pt(NH3)2Cl2. Pt ≥65.0%. |  |
| PC-046 | PC-046 is a potent tubulin-binding agent, which was originally identified for development based on selective activity in deleted in pancreas cancer locus 4 (DPC4/SMAD4) deficient tumors. PC-046 has growth inhibitory activity in a variety of tumor types in vitro, and efficacy in SCID mice was shown in human tumor xenografts of MV-4-11 acute myeloid leukemia, MM.1S multiple myeloma, and DU-145 prostate cancer. Pharmacokinetic studies demonstrated relatively high oral bioavailability (71 %) with distribution to both plasma and bone marrow. No myelosuppression was seen in non-tumor bearing SCID mice given a single dose just under the acute lethal dose. The COMPARE algorithm in the NCI-60 cell line panel demonstrated that PC-046 closely correlated to other known tubulin destabilizing agents (correlation coefficients ?0.7 for vincristine and vinblastine). Mechanism of action studies showed cell cycle arrest in metaphase and inhibition of tubulin polymerization. Overall, these studies show that PC-046 is a synthetically-derived, small molecule microtubule destabilizing agent. Advantages over existing microtubule destabilizing agents include ease of synthesis, lack of MDR cross-resistance, good oral bioavailability and the lack of acute myelotoxicity. Synonyms: PC 046; PC046; NSC-756784; 5-(4-methoxyphenyl)-2-(3-(3-methoxyphenyl)pyridin-4-yl)oxazole. Grades: 98%. CAS No. 1202401-59-9. Molecular formula: C22H18N2O3. Mole weight: 358.39. | |
| Phomopsin A | It is an acidic 13-membered cyclic hexapeptide-like metabolite with three unusual amino acids. It is a potent mycotoxin produced by the fungus, phomopsis leptostromiformis. It is an important bioprobe for understanding cellular structural proteins. It selectively binds to the dimeric tubulin at the overlap of vinblastine and maytansine, inhibits the formation of the microtubule spindle to block cell division. Synonyms: 2-Oxa-5,8-diazabicyclo[10.3.1]hexadecane, cyclic peptide deriv.; (2E)-(βS)-3-chloro-β,5-dihydroxy-N-methyl-L-tyrosyl-3,4-didehydro-L-valyl-3-hydroxy-L-isoleucyl-3,4-didehydro-L-prolyl-(2E)-2,3-didehydroisoleucyl-2,3-didehydro-aspartic acid, cyclic (15?3)-ether; NSC 381839; PMSA; Phomopsin. Grades: >98% by HPLC. CAS No. 64925-80-0. Molecular formula: C36H45ClN6O12. Mole weight: 789.23. | |
| Phomopsin A | Phomopsin A is an acidic 13-membered cyclic hexapeptide-like metabolite with three unusual amino acids linked in an "ansa" macrocycle with a three amino acid "tail", terminating in a dicarboxylic acid. Phomopsin A is a potent mycotoxin produced by the fungus Phomopsis leptostromiformis and is the causative agent of lupinosis in livestock fed infected lupins. Phomopsin A is an important bioprobe for understanding cellular structural proteins. It acts by selectively binding to dimeric tubulin, inhibiting the formation of the microtubule spindle to block cell division. Phomopsin A binds to tubulin at a site overlapping that of vinblastine and maytansine. Uniquely, phomopsin A protects tubulin from decay. Group: Biochemicals. Alternative Names: 2-Oxa-5, 8-diazabicyclo[10. 3. 1]hexadecane, cyclic peptide deriv.; 3-Chloro-erythro- β,5-dihydroxy-N-methyl-L-tyrosyl-3,4-didehydro-L-valyl-3-hydroxy-L-isoleucyl-3,4-didehydro-L-prolyl-(E)-2,3-didehydroisoleucyl-(E)-2,3-didehydroaspartic acid cyclic (15?3)-ether; NSC 381839. Grades: Highly Purified. CAS No. 64925-80-0. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Secologanin | Secologanin, a secoiridoid glucoside, is a pivotal terpenoid intermediate in the biosynthesis of biologically active monoterpenoid indole alkaloids such as reserpine, ajmaline, and vinblastine. Secologanin synthase (cytochrome P450 isoform CYP72A1) catalyzes the oxidative cleavage of loganin into Secologanin [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 19351-63-4. Pack Sizes: 1 mg. Product ID: HY-125598. | |
| Vindesine EP Impurity C | Vindesine EP Impurity C is a cytotoxic alkaloid often conjugated with folic acid to produce EC145, a novel folate-receptor targeted agent with an antitumor property. Synonyms: Desacetyl Vinblastine Hydrazide; 4-Desacetylvinblastine 3-carbohydrazide; 4-Desacetylvinblastine 3-carboxyhydrazide 4-Desacetylvincaleukoblastine 3-carboxyhydrazide; Deacetylvinblastine hydrazide; Desacetylvinblastine hydrazide. CAS No. 55383-37-4. Molecular formula: C43H56N6O7. Mole weight: 768.96. | |
| Vindesine Sulfate Salt (LY-099094, Eldisine, Fildesin) | Synthetic derivative of the dimeric Catharanthus alkaloid vinblastine. Antineoplastic. Group: Biochemicals. Alternative Names: LY-099094; Eldisine; Fildesin. Grades: Highly Purified. CAS No. 59917-39-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Vintafolide | Vintafolide is a water-soluble, folate-receptor-targeted conjugate of folate and the vinca alkaloid desacetylvinblastine monohydrazide (DAVLBH) with potential antineoplastic activity. The folate moiety of folate-vinca alkaloid conjugate EC145 binds to folic acid receptors on the tumor cell surface and the agent is internalized via folate receptor-mediated endocytosis, delivering the tubulin-binding DAVLBH moiety directly into the tumor cell; DAVLBH binding to tubulin results in the disruption of microtubule assembly-disassembly dynamics, cell cycle arrest, and tumor cell apoptosis. Folic acid receptors are frequently upregulated on the surfaces of many tumor cell types. DAVLBH is a derivative of the natural product vinblastine. Synonyms: EC-145; EC 145; EC145; KM-8109; KM 8109; KM8109; Vintafolide. CAS No. 742092-03-1. Molecular formula: C86H109N21O26S2. Mole weight: 1917.06. | |
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