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| Product | Description | |
|---|---|---|
| xanthine oxidase | An iron-molybdenum flavoprotein (FAD) containing [2Fe-2S] centres. Also oxidizes hypoxanthine, some other purines and pterins, and aldehydes, but is distinct from EC 1.2.3.1, aldehyde oxidase. Under some conditions the product is mainly superoxide rather than peroxide: RH + H2O + 2 O2 = ROH + 2 O2.- + 2 H+. The mammalian enzyme predominantly exists as an NAD-dependent dehydrogenase (EC 1.17.1.4, xanthine dehydrogenase). During purification the enzyme is largely converted to the O2-dependent xanthine oxidase form (EC 1.17.3.2). The conversion can be triggered by several mechanisms, including the oxidation of cysteine thiols to form disulfide bonds [which can be catalysed by EC 1.8.4.7, enzyme-thiol transhydrogenase (glutathione-disulfide) in the presence of glutathione disulfide] or limited proteolysis, which results in irreversible conversion. The conversion can also occur in vivo. Group: Enzymes. Synonyms: hypoxanthine o. Enzyme Commission Number: EC 1.17.3.2. CAS No. 9002-17-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1088; xanthine oxidase; EC 1.17.3.2; 9002-17-9; hypoxanthine oxidase; hypoxanthine:oxygen oxidoreductase; Schardinger enzyme; xanthine oxidoreductase; hypoxanthine-xanthine oxidase; xanthine:O2 oxidoreductase; xanthine:xanthine oxidase. Cat No: EXWM-1088. |  |
| Xanthine Oxidase from Arthrobacter sp. | Xanthine oxidase is a form of xanthine oxidoreductase, a type of enzyme that generates reactive oxygen species. These enzymes catalyze the oxidation of hypoxanthine to xanthine and can further catalyze the oxidation of xanthine to uric acid. These enzymes play an important role in the catabolism of purines in some species, including humans. Group: Enzymes. Synonyms: EC 1.17.3.2; Xanthine oxidase; XO; XAO. Enzyme Commission Number: EC 1.17.3.2. CAS No. 9002-17-9. Mole weight: 160 kDa (gel). Activity: >50U/mg protein. Storage: Store at -20°C. Form: Reddish brown amorphous powder, lyophilized. Source: Arthrobacter sp. EC 1.17.3.2; Xanthine oxidase; XO; XAO; XOD. Cat No: NATE-1719. | |
| Native Bovine Xanthine Oxidase | Xanthine oxidase is a molybdenum-containing enzyme that is found in the cytosol, and may be strongly inhibited by flavonoids. It plays a vital role in the metabolism of some drugs, as well as purines and pyrimidines. It is also known to be a biological source of reactive oxygen species. Xanthine oxidase was shown to be involved in the reduction of cytochrome c by the generation of superoxide anions following the oxidation of xanthine. These free radicals are responsible for reducing cytochrome c. Formerly e.c. 1.1.3.22. Group: Enzymes. Synonyms: Xanthine oxidase; XO; xanthine oxidoreductase; EC 1.17.3.2; 9002-17-9; XOD; Xanthine:oxygen oxidoreductase; hypoxanthine oxidase; hyp...in. Storage: 2-8°C. Form: Type I, Type II, ammonium sulfate suspension; Suspension in 2.3 M (NH4)2SO4 containing 1 mM sodium salicylate; Type III, ammonium sulfate suspension, Suspension in 2.3 M (NH4)2SO4, 10 mM sodium phosphate buffer, pH 7.8, containing 1 mM EDTA and 1 mM sodium salicylate; Type IV, lyophilized powder, Contains 0.5% sodium salicylate. Source: Bovine milk. Species: Bovine. Xanthine oxidase; XO; xanthine oxidoreductase; EC 1.17.3.2; 9002-17-9; XOD; Xanthine:oxygen oxidoreductase; hypoxanthine oxidase; hypoxanthine:oxygen oxidoreductase; Schardinger enzyme; hypoxanthine-xanthine oxidase; xanthine:O2 oxidoreductase; xanthine:xanthine oxidase. Cat No: NATE-0732. | |
| Native Microbial Xanthine Oxidase | Xanthine oxidase is a molybdenum-containing enzyme that is found in the cytosol, and may be strongly inhibited by flavonoids. It plays a vital role in the metabolism of some drugs, as well as purines and pyrimidines. It is also known to be a biological source of reactive oxygen species. Xanthine oxidase was shown to be involved in the reduction of cytochrome c by the generation of superoxide anions following the oxidation of xanthine. These free radicals are responsible for reducing cytochrome c. Allopurinol is a synthetic drug show to inhibit xanthine oxidase. Applications: This enzyme is useful for enzymatic determination of inorganic phosphorus, 5?-nucleotidase and adenosine deaminase when coupled with purine-nucleoside phosphorylase and uricase. Group: Enzymes. Synonyms: Xanthine oxidase; XO; xanthine oxidoreductase; EC 1.17. Enzyme Commission Number: EC 1.17.3.2. CAS No. 9002-17-9. XAO. Mole weight: mol wt ~160 kDa. Activity: > 7 units/mg solid. Storage: -20°C. Form: Lyophilized powder containing BSA and sodium glutamate as stabilizers. Source: Microbial. Xanthine oxidase; XO; xanthine oxidoreductase; EC 1.17.3.2; 9002-17-9; XOD; Xanthine:oxygen oxidoreductase; hypoxanthine oxidase; hypoxanthine:oxygen oxidoreductase; Schardinger enzyme; hypoxanthine-xanthine oxidase; xanthine:O2 oxidoreductase; xanthine:xanthine oxidase. Cat No: NATE-0733. | |
| Native Microorganism Xanthine oxidase | Xanthine oxidase is a form of xanthine oxidoreductase, a type of enzyme that generates reactive oxygen species. These enzymes catalyze the oxidation of hypoxanthine to xanthine and can further catalyze the oxidation of xanthine to uric acid. These enzymes play an important role in the catabolism of purines in some species, including humans. Applications: This enzyme is useful for enzymatic determination of inorganic phosphorus, 5'-nucleotidase and adenosine deaminase when coupled with purine-nucleoside phosphorylase and uricase. Group: Enzymes. Synonyms: EC 1.1.3.22; Xanthine oxidase; XO; XAO. Enzyme Commission Number: EC 1.1.3.22. CAS No. 9054-84-6. XAO. Mole weight: approx. 160 kDa. Activity: Grade? 10U/mg-solid or more. Stability: Stable at-20°C for at least year. Appearance: Reddish brown amorphous powder, lyophilized. Source: Microorganism. EC 1.1.3.22; Xanthine oxidase; XO; XAO. Cat No: DIA-218. | |
| 1-Cyclopropyl-2-nitro-naphthalene | 1-Cyclopropyl-2-nitro-naphthalene is an impurity of drug Lesinurad (L329700), which is used to synthesize febuxostat which is a non-purine analog inhibitor of xanthine oxidase. Febuxostat is approved by the European Medicines Agency and the US Food and Drug Administration for treating gout. Group: Biochemicals. Grades: Highly Purified. CAS No. 1802080-61-0. Pack Sizes: 10mg, 25mg. Molecular Formula: C13H11NO2, Molecular Weight: 213.23. US Biological Life Sciences. |  Worldwide |
| 1-Methyl-1H-pyrrole-2-carbaldehyde | 1-Methyl-1H-pyrrole-2-carbaldehyde is a substance for the toxicological evaluation of aerosols of a tobacco extract formulation and nicotine formulations in acute and short-term inhalation studies. A substance for ligand-based screening of chemical constituents of Glycyrrhiza glabra in search of inhibitors of xanthine oxidase. Group: Biochemicals. Grades: Highly Purified. CAS No. 1192-58-1. Pack Sizes: 5g, 10g. Molecular Formula: C6H7NO. US Biological Life Sciences. | Worldwide |
| 2-(1-Benzyl-1H-indazol-3-yloxy)acetic Acid | Bendazac is a non-steroidal anti-inflammatory drug (NSAID) used for joint and muscular pain, which is also known as AF-983 (an anticataract drug). It was found to inhibit only reversible and irreversible xanthine oxidase. Bendazac also inhibits the denaturing of proteins. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: 2-[[1-(phenylmethyl)-3-indazolyl]oxy]acetic acid; 2-(1-benzylindazol-3-yl)oxyacetic acid. Grades: ≥ 98 %. CAS No. 20187-55-7. Molecular formula: C16H14N2O3. Mole weight: 282.29. |  |
| 2-(3,5-dicyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid | 2-(3,5-dicyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid is an impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. CAS No. 2428631-65-4. Molecular formula: C17H15N3O3S. Mole weight: 341.39. | |
| 2-(3,5-Diformyl-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic Acid | 2-(3,5-Diformyl-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic Acid s an impurity of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C17H17NO5S, Molecular Weight: 347.39. US Biological Life Sciences. | Worldwide |
| 2-(3-bromo-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid | An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: 3-Descyano 3-Bromo-febuxostat; Bromo febuxostat impurity; Febuxostat Impurity D. CAS No. 144060-40-2. Molecular formula: C15H16BrNO3S. Mole weight: 370.26. | |
| 2-[3-Cyano-4-(3-hydroxy-2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic Acid Ethyl Ester | 2-[3-Cyano-4-(3-hydroxy-2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic Acid Ethyl Ester is an intermediate in synthesizing Febuxostat 67M-4 (F229015), which is a derivative compound of Febuxostat 67M-1 (F229005) which is an inhibitor of xanthine oxidase. It reduces uric acid production in the body and also used to reduce the risk of gout or kidney stone formation. Group: Biochemicals. Grades: Highly Purified. CAS No. 1572503-72-0. Pack Sizes: 10mg, 25mg. Molecular Formula: C18H20N2O4S. US Biological Life Sciences. | Worldwide |
| 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid 1-oxide | 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid 1-oxide is an impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. CAS No. 2418591-42-9. Molecular formula: C16H16N2O4S. Mole weight: 332.37. | |
| 2-(3-cyano-4-isobutoxyphenyl)-N,N,4-trimethylthiazole-5-carboxamide | An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: Febuxostat Impurity 66. Grades: 99%. CAS No. 1380049-45-5. Molecular formula: C18H21N3O2S. Mole weight: 343.44. | |
| 2-(3-cyano-4-propoxyphenyl)-4-methylthiazole-5-carboxylic acid | An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: O-Desisobutyl-O-n-propyl Febuxostat; Febuxostat N-Propyl Ether Acid Impurity; Febuxostat Impurity U. CAS No. 1530308-87-2. Molecular formula: C15H14N2O3S. Mole weight: 302.35. | |
| 2,3-Dichlorobenzoyl chloride | 2,3-Dichlorobenzoyl chloride is used in the preparation of xanthine oxidase inhibitory activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 2905-60-4. Pack Sizes: 1g, 5g. Molecular Formula: C7H3Cl3O. US Biological Life Sciences. | Worldwide |
| 2-(3-formyl-4-isobutoxyphenyl)-N,N,4-trimethylthiazole-5-carboxamide | An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: Febuxostat Impurity 105; Febuxostat Impurity 65. CAS No. 1380049-42-2. Molecular formula: C18H22N2O3S. Mole weight: 346.44. | |
| 2-[[4-(1-Naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid | 2-[[4-(1-Naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid is an impurity of drug Lesinurad (L329700), which is used to synthesize febuxostat which is a non-purine analog inhibitor of xanthine oxidase. Febuxostat is approved by the European Medicines Agency and the US Food and Drug Administration for treating gout. Group: Biochemicals. Grades: Highly Purified. CAS No. 1038366-57-2. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C14H11N3O2S, Molecular Weight: 285.32. US Biological Life Sciences. | Worldwide |
| 2-[4-(2-Carboxypropoxy)-3-cyanophenyl]-4-methyl-5-thiazolecarboxylic Acid 5-Ethyl Ester | 2-[4-(2-Carboxypropoxy)-3-cyanophenyl]-4-methyl-5-thiazolecarboxylic Acid 5-Ethyl Ester is an intermediate in synthesizing Febuxostat 67M-4 (F229015), which is a derivative compound of Febuxostat 67M-1 (F229005) which is an inhibitor of xanthine oxidase. It reduces uric acid production in the body and also used to reduce the risk of gout or kidney stone formation. Group: Biochemicals. Grades: Highly Purified. CAS No. 1572503-76-4. Pack Sizes: 5mg, 10mg. Molecular Formula: C18H18N2O5S. US Biological Life Sciences. | Worldwide |
| 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid | 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid is an impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: 2-(4-hydroxyphenyl)-4-methyl-5-thiazolecarboxylic acid; 2-(4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic acid. CAS No. 886501-78-6. Molecular formula: C11H9NO3S. Mole weight: 235.26. | |
| 2-(4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid | An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: 3-Descyano Febuxostat; Febuxostat Impurity IV; Febuxostat Descyano Impurity; Febuxostat Impurity E; 5-Thiazolecarboxylic acid, 4-methyl-2-[4-(2-methylpropoxy)phenyl]-. CAS No. 1206550-99-3. Molecular formula: C15H17NO3S. Mole weight: 291.37. | |
| 2-(4-(sec-butoxy)-3-cyanophenyl)-4-methylthiazole-5-carboxylic acid | An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: Febuxostat sec-butoxy acid; Febuxostat 2-Butyl Isomer; Febuxostat Impurity J; 5-Thiazolecarboxylic acid, 2-[3-cyano-4-(1-methylpropoxy)phenyl]-4-methyl-. CAS No. 1335202-59-9. Molecular formula: C16H16N2O3S. Mole weight: 316.37. | |
| 2-(4-(tert-butoxy)-3-cyanophenyl)-4-methylthiazole-5-carboxylic acid | An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: Febuxostat Impurity 70; 5-Thiazolecarboxylic acid, 2-[3-cyano-4-(1,1-dimethylethoxy)phenyl]-4-methyl-. CAS No. 2418591-43-0. Molecular formula: C16H16N2O3S. Mole weight: 316.37. | |
| 2-[[5-Bromo-4-(1-cyclopropyl-2-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid | 2-[[5-Bromo-4-(1-cyclopropyl-2-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid is an impurity of drug Lesinurad (L329700), which is used to synthesize febuxostat which is a non-purine analog inhibitor of xanthine oxidase. Febuxostat is approved by the European Medicines Agency and the US Food and Drug Administration for treating gout. Group: Biochemicals. Grades: Highly Purified. CAS No. 1533519-94-6. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C17H14BrN3O2S, Molecular Weight: 404.28. US Biological Life Sciences. | Worldwide |
| 2-[[5-Bromo-4-(4-propyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid | 2-[[5-Bromo-4-(4-propyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid is an impurity of drug Lesinurad (L329700), which is used to synthesize febuxostat which is a non-purine analog inhibitor of xanthine oxidase. Febuxostat is approved by the European Medicines Agency and the US Food and Drug Administration for treating gout. Group: Biochemicals. Grades: Highly Purified. CAS No. 1533519-96-8. Pack Sizes: 10mg, 25mg. Molecular Formula: C17H16BrN3O2S, Molecular Weight: 406.3. US Biological Life Sciences. | Worldwide |
| 2-[[5-Bromo-4-(5-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid | 2-[[5-Bromo-4-(5-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid is an impurity of drug Lesinurad (L329700), which is used to synthesize febuxostat which is a non-purine analog inhibitor of xanthine oxidase. Febuxostat is approved by the European Medicines Agency and the US Food and Drug Administration for treating gout. Group: Biochemicals. Grades: Highly Purified. CAS No. 1533519-97-9. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C17H14BrN3O2S, Molecular Weight: 404.28. US Biological Life Sciences. | Worldwide |
| 2-[[5-Bromo-4-(naphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid | 2-[[5-Bromo-4-(naphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid is an impurity of drug Lesinurad (L329700), which is used to synthesize febuxostat which is a non-purine analog inhibitor of xanthine oxidase. Febuxostat is approved by the European Medicines Agency and the US Food and Drug Administration for treating gout. Group: Biochemicals. Grades: Highly Purified. CAS No. 1210330-64-5. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C14H10BrN3O2S, Molecular Weight: 364.22. US Biological Life Sciences. | Worldwide |
| 2-Aminoanthraquinone | 2-Aminoanthraquinone is a reagent used in the synthesis of isonicotinic carboxamide derivatives used as anti-hyperlipidemic agents. 2-Aminoanthraquinone also displays xanthine oxidase inhibitory activity and antimalarial activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 117-79-3. Pack Sizes: 5g, 10g. Molecular Formula: C14H9NO2, Molecular Weight: 223.23. US Biological Life Sciences. | Worldwide |
| 2-Cyclopropyl-1-nitro-naphthalene | 2-Cyclopropyl-1-nitro-naphthalene is an impurity of drug Lesinurad (L329700), which is used to synthesize febuxostat which is a non-purine analog inhibitor of xanthine oxidase. Febuxostat is approved by the European Medicines Agency and the US Food and Drug Administration for treating gout. Group: Biochemicals. Grades: Highly Purified. CAS No. 52331-35-8. Pack Sizes: 10mg, 25mg. Molecular Formula: C13H11NO2, Molecular Weight: 213.23. US Biological Life Sciences. | Worldwide |
| 2'-Deoxyguanosine N1-(Ethyl Acrylate) | 2'-Deoxyguanosine N1-(Ethyl Acrylate) is an intermediate in the synthesis of 3-(2-Deoxy-β-D-erythro-pentofuranosyl)-3,5-dihydropyrimido[1,2-a]purine-6,10-dione. 3-(2-Deoxy-β-D-erythro-pentofuranosyl)-3,5-dihydropyrimido[1,2-a]purine-6,10-dione is likely an endogenous biomarker in humans and is readily generated from M1dG in liver cytosol, which involves xanthine oxidase and aldehyde oxidase. Synonyms: 3-[2-Amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-6,9-dihydro-6-oxo-1H-purin-1-yl]-2-propenoic Acid Ethyl Ester. CAS No. 895571-80-9. Molecular formula: C15H19N5O6. Mole weight: 365.34. | |
| 2-Deoxyguanosine N1-(Ethyl Acrylate) | 2-Deoxyguanosine N1-(Ethyl Acrylate) is an intermediate in the synthesis of 3-(2-Deoxy- β-D-erythro-pentofuranosyl)-3,5-dihydropyrimido[1,2-a]purine-6,10-dione (D235185). 3-(2-Deoxy- β-D-erythro-pentofuranosyl)-3,5-dihydropyrimido[1,2-a]purine-6,10-dione is likely an endogenous biomarker in humans and is readily generated from M1dG in liver cytosol, which involves xanthine oxidase and aldehyde oxidase. Group: Biochemicals. Grades: Highly Purified. CAS No. 895571-80-9. Pack Sizes: 5mg, 10mg. Molecular Formula: C15H19N5O6, Molecular Weight: 365.34. US Biological Life Sciences. | Worldwide |
| 2-hydroxy-5-(4-methylthiazol-2-yl)benzaldehyde | 2-hydroxy-5-(4-methylthiazol-2-yl)benzaldehyde is an impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: Febuxostat Impurity 58; 2-(3-carbamoyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid. CAS No. 2227293-68-5. Molecular formula: C11H9NO2S. Mole weight: 219.26. | |
| 3-(2-Deoxy- β-D-erythro-pentofuranosyl)-3,5-dihydropyrimido[1,2-a]purine-6,10-dione | 3-(2-Deoxy- β-D-erythro-pentofuranosyl)-3,5-dihydropyrimido[1,2-a]purine-6,10-dione is likely an endogenous biomarker in humans and is readily generated from M1dG in liver cytosol, which involves xanthine oxidase and aldehyde oxidase. Group: Biochemicals. Grades: Highly Purified. CAS No. 895571-79-6. Pack Sizes: 1mg, 5mg. Molecular Formula: C13H13N5O5. US Biological Life Sciences. | Worldwide |
| 3,5-dipyridyl-1,2,4-triazole | One of the impurities of Topiroxostat, which is a xanthine oxidase inhibitor and has been found to be effective in the treatment of gout and hyperuricemia. Synonyms: 4,4'-(1H-1,2,4-triazole-3,5-diyl)dipyridine; 3,5-Di(4-pyridyl)-1,2,4-triazole. CAS No. 4329-78-6. Molecular formula: C12H9N5. Mole weight: 223.24. | |
| 3-Benzyloxy-4-hydroxybenzaldehyde | A reactant used in the preparation of PDE4 and PDE7 inhibitors, insulin-like growth-factor-I receptor (IGF-IR) inhibitors and ferulic acid derivatives as xanthine oxidase inhibitors. Group: Biochemicals. Alternative Names: 4-Hydroxy-3-(phenylmethoxy)-benzaldehyde; 3-(Phenylmethoxy)-4-hydroxybenzaldehyde; 4-Hydroxy-3- (phenylmethoxy) benzaldehyde. Grades: Highly Purified. CAS No. 50773-56-3. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| 4-Amino-6-mercaptopyrazolo[3,4-d]pyrimidine | Pyrazolo[3,4-d]pyrimidines have a close structural resemblance to the substrates for the enzyme xanthine oxidase, hypoxanthine (6-hydroxypurine) and xanthine (2. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| 5-(5-(ethoxycarbonyl)-4-methylthiazol-2-yl)-2-isobutoxybenzoic acid | 5-(5-(ethoxycarbonyl)-4-methylthiazol-2-yl)-2-isobutoxybenzoic acid is an impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: 5-(5-(ethoxycarbonyl)-4-methylthiazol-2-yl)-2-isobutoxybenzoic acid; 2095166-41-7. CAS No. 2095166-41-7. Molecular formula: C18H21NO5S. Mole weight: 363.43. | |
| 5,6-Dichlorobenzimidazole | A benzimidazole derivative as potent inhibitor of milk xanthine oxidase. Group: Biochemicals. Alternative Names: 5,6-Dichloro-1H-benzimidazole; NSC 326397; NSC 63938. Grades: Highly Purified. CAS No. 6478-73-5. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| 5-Hydroxy-3,4,7-triphenyl-2,6-benzofurandione | 5-Hydroxy-3,4,7-triphenyl-2,6-benzofurandione is a xanthine oxidase (XO) inhibitor produced by Peniophora sanguinea. Synonyms: 5-Hydroxy-3,4,7-triphenylbenzofuran-2,6-dione. Molecular formula: C26H16O4. Mole weight: 392.40. | |
| 6-Aminoallopurinol riboside | 6-Aminoallopurinol riboside is a pharmacological entity, finding application in the research of specific ailments linked to malfunctions in purine metabolism. It exerts its mode of action through the suppression of xanthine oxidase, an enzymatic catalyst in the degradation pathway of purine. Synonyms: 7-deaza-8-azaguanosine; 6-Amino-1,5-dihydro-1-(b-D-ribofuranosyl)-4H-pyrazolo[3,4-d]pyrimidin-4-one; 6-Amino-1-beta-D-ribofuranosylpyrazolo(3,4-d)pyrimidin-4-one; 6-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one. Grades: ≥95%. CAS No. 85426-74-0. Molecular formula: C10H13N5O5. Mole weight: 283.24. | |
| 6-Formylpterin | 6-Formylpterin is an inhibitor of Xanthine Oxidase. 6-Formylpterin induces intracellular ROS generation and apoptosis in HL-60 cells. 6-Formylpterin suppresses cell proliferation in PanC-1 cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 712-30-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-113978. |  |
| 6-Formylpterin | 6-Formylpterin is a pteridine derivative that acts as a xanthine oxidase inhibitor. Synonyms: Pterin-6-aldehyde; 2-Amino-4-hydroxy-6-formylpteridine. Grades: 95%. CAS No. 712-30-1. Molecular formula: C7H5N5O2. Mole weight: 191.15. | |
| (6R)-5,6,7,8-Tetrahydro-L-biolumazine | (6R)-5,6,7,8-Tetrahydro-L-biolumazine is a derivative of Biolumazine, which is a xanthine oxidase inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C9H14N4O4, Molecular Weight: 242.23. US Biological Life Sciences. | Worldwide |
| 7,8,3,4-Tetrahydroxyflavone | 7,8,3,4-Tetrahydroxyflavone (compound 2) is a potent xanthine oxidase (XOD) inhibitor with an IC 50 value of 10.488 μM [1]. Uses: Scientific research. Group: Natural products. CAS No. 3440-24-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N8600. | |
| aldehyde dehydrogenase (FAD-independent) | Belongs to the xanthine oxidase family of enzymes. The enzyme from Desulfovibrio sp. contains a molybdenum-molybdopterin-cytosine dinucleotide (MCD) complex and two types of [2Fe-2S] cluster per monomer, but does not contain FAD. Group: Enzymes. Synonyms: aldehyde oxidase; aldehyde oxidoreductase; Mop; AORDd. Enzyme Commission Number: EC 1.2.99.7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1235; aldehyde dehydrogenase (FAD-independent); EC 1.2.99.7; aldehyde oxidase; aldehyde oxidoreductase; Mop; AORDd. Cat No: EXWM-1235. | |
| Allopurinol | Allopurinol is a potent and orally active xanthine oxidase inhibitor with an IC 50 value of 0.2-50 μM. Allopurinol can be used in the research of hyperuricemia and gout. Allopurinol decreases the expression of HIF-1α and HIF-2α protein. Allopurinol shows anti-depressant and anti-nociception activity. Anti-leishmanial effect [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 315-30-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g; 10 g. Product ID: HY-B0219. | |
| Allopurinol | Xanthine oxidase inhibitor; decreases uric acid production. Used in treatment of hyperuricemia and chronic gout. Antiurolithic. Group: Biochemicals. Alternative Names: 1,5-Dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one; 4-Hydroxypyrazolo[3,4-d]pyrimidine; 4-Oxopyrazolo[3,4-d]pyrimidine; Adenock; Allopur; Caplenal; Cellidrin; NSC 101655; NSC 1390. Grades: Highly Purified. CAS No. 315-30-0. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| Allopurinol-d2 | Labeled xanthine oxidase inhibitor; decreases uric acid production. Used in treatment of hyperuricemia and chronic gout. Antiurolithic. Group: Biochemicals. Alternative Names: 1,5-Dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one-d2; 4-Hydroxypyrazolo[3,4-d]pyrimidine-d2; 4-Oxopyrazolo[3,4-d]pyrimidine-d2; Adenock-d2; Allopur-d2; Caplenal-d2; Cellidrin-d2; NSC 101655-d2; NSC 1390-d2. Grades: Highly Purified. CAS No. 916979-34-5. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Allopurinol riboside | Allopurinol riboside is a noteworthy compound, astutely used in research of kidney stones and hyperuricemia, wielding its powers as a potent xanthine oxidase inhibitor. By hindering uric acid compoundion, it proficiently mitigates the jeopardy of crystal deposition. Uses: Antiprotozoal agents. Synonyms: Allopurinol riboside; 16220-07-8; Allopurinol ribonucleoside; Allopurinol-1-ribonucleoside; WZS8452SEC; 4-Hydroxy[3,4-d]pyrazolopyrimidine riboside; CHEMBL1688966; CHEBI:74074; 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,5-dihydro-1-beta-D-ribofuranosyl-; 4-Hydroxy(3,4-d)pyrazolopyrimidine riboside; 1-[(2R,3R,4S,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-5H-PYRAZOLO[3,4-D]PYRIMIDIN-4-ONE; 1-beta-D-Ribofuranosyl-1H-pyrazolo[3,4-d]pyrimidine-4-one; 4H-Pyrazolo(3,4-d)pyrimidin-4-one, 1,5-dihydro-1-.beta.-D-ribofuranosyl-1111. Grades: ≥ 97%. CAS No. 16220-07-8. Molecular formula: C10H12N4O5. Mole weight: 268.23. | |
| Allopurinol sodium | Allopurinol sodium is a potent and orally active xanthine oxidase inhibitor with an IC 50 value of 0.2-50 μM. Allopurinol sodium can be used in the research of hyperuricemia and gout. Allopurinol sodium decreases the expression of HIF-1α and HIF-2α protein. Allopurinol sodium shows anti-depressant and anti-nociception activity. Anti-leishmanial effect [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 17795-21-0. Pack Sizes: 10 mg; 25 mg. Product ID: HY-B0219A. | |
| Allopurinol Sodium | Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM. Synonyms: Sodium allopurinol; Allopurinol sodium salt; NSC 108836; 1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one,monosodiumsalt. Grades: >98%. CAS No. 17795-21-0. Molecular formula: C5H3N4NaO. Mole weight: 158.09. | |
| Allopurinol (Standard) | Allopurinol (Standard) is the analytical standard of Allopurinol. This product is intended for research and analytical applications. Allopurinol is a potent and orally active xanthine oxidase inhibitor with an IC50 value of 0.2-50 μM. Allopurinol can be used in the research of hyperuricemia and gout. Allopurinol decreases the expression of HIF-1α and HIF-2α protein. Allopurinol shows anti-depressant and anti-nociception activity. Anti-leishmanial effect [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 315-30-0. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-B0219R. | |
| Amflutizole | Amflutizole is a xanthine oxidase inhibitor. It inhibits free radical generation in the ischemic/reperfused rat cerebral cortex. Synonyms: 4-Amino-3-(3-(trifluoromethyl)phenyl)isothiazole-5-carboxylic acid. CAS No. 82114-19-0. Molecular formula: C11H7F3N2O2S. Mole weight: 288.25. | |
| Anthragallol | Anthragallol is the most active inhibitor against xanthine oxidase. Group: Biochemicals. Alternative Names: 1,2,3-Trihydroxy-9,10-anthracenedione; 1,2,3-Trihydroxy-9,10-anthraquinone; 1, 2, 3-Tri hydroxyanthraquinone; Alizarine Brown HD; Anthracene Brown FD; Anthracene; Antracromo Brown D; Antragallol; C.I. 58200. Grades: Highly Purified. CAS No. 602-64-2. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| Baicalein | Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor with an IC50 value of 3.12 μM. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Noroxylin. Product Category: Inhibitors. Appearance: Yellow solid. CAS No. 491-67-8. Molecular formula: C15H10O5. Mole weight: 270.24. Purity: 0.98. IUPACName: 5,6,7-Trihydroxy-2-phenylchromen-4-one. Canonical SMILES: C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=C(C(=C3O)O)O. Density: 1.3280 g/cm³. Product ID: ACM491678. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Baicalein | Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor with an IC 50 value of 3.12 μM. Uses: Scientific research. Group: Natural products. Alternative Names: 5,6,7-Trihydroxyflavone. CAS No. 491-67-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-N0196. | |
| diethyl 2,2'-(4-isobutoxy-1,3-phenylene)bis(4-methylthiazole-5-carboxylate) | diethyl 2,2'-(4-isobutoxy-1,3-phenylene)bis(4-methylthiazole-5-carboxylate) is an impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: Diethyl 2,2'-(4-isobutoxy-1,3-phenylene)bis(4-methyl-1,3-thiazole-5-carboxylate). CAS No. 1346238-13-8. Molecular formula: C24H28N2O5S2. Mole weight: 488.62. | |
| (±)-Dihydroactinidiolide | (±)-Dihydroactinidiolide, an important aroma compound of black tea and tobacco, has been isolated from several plants. (±)-Dihydroactinidiolide can be formation from β-Carotene by the treatment of polyphenoloxidase, the lipoxygenase, and the xanthine oxidase [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 15356-74-8. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-W041301. | |
| enzyme-thiol transhydrogenase (glutathione-disulfide) | Converts EC 1.17.1.4 xanthine dehydrogenase into EC 1.17.3.2 xanthine oxidase in the presence of glutathione disulfide; also reduces the disulfide bond of ricin. Not inhibited by Cu2+ or thiol reagents. Group: Enzymes. Synonyms: [xanthine-dehydrogenase]:oxidized-glutathione S-oxidoreductase; enzyme-thiol transhydrogenase (oxidized-glutathione); glutathione-dependent thiol:disulfide oxidoreductase; thiol:disulphide oxidoreductase. Enzyme Commission Number: EC 1.8.4.7. CAS No. 85030-79-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1673; enzyme-thiol transhydrogenase (glutathione-disulfide); EC 1.8.4.7; 85030-79-1; [xanthine-dehydrogenase]:oxidized-glutathione S-oxidoreductase; enzyme-thiol transhydrogenase (oxidized-glutathione); glutathione-dependent thiol:disulfide oxidoreductase; thiol:disulphide oxidoreductase. Cat No: EXWM-1673. | |
| ethyl 2-(2-(3-hydroxyphenyl)thiazol-4-yl)acetate | An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: Febuxostat Impurity 61; 4-Thiazoleacetic acid, 2-(3-hydroxyphenyl)-, ethyl ester. CAS No. 171017-48-4. Molecular formula: C13H13NO3S. Mole weight: 263.31. | |
| ethyl 2-(3,5-dicyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate | ethyl 2-(3,5-dicyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate is an impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. CAS No. 2428631-67-6. Molecular formula: C19H19N3O3S. Mole weight: 369.44. | |
| ethyl 2-(3,5-diformyl-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate | ethyl 2-(3,5-diformyl-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylat is an impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: Ethyl 2-(3,5-diformyl-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate. CAS No. 2375033-26-2. Molecular formula: C19H21NO5S. Mole weight: 375.44. | |
| ethyl 2-(3-carbamoyl-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate | ethyl 2-(3-carbamoyl-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate is an impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: SCHEMBL458831; ethyl 2-(3-carbamoyl-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate; 1346238-15-0. CAS No. 1346238-15-0. Molecular formula: 18H22N2O4S. Mole weight: 362.44. | |
| ethyl 2-(4-butoxy-3-cyanophenyl)-4-methylthiazole-5-carboxylate | ethyl 2-(4-butoxy-3-cyanophenyl)-4-methylthiazole-5-carboxylate is an impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. CAS No. 2230270-05-8. Molecular formula: C18H20N2O3S. Mole weight: 344.43. | |
| ethyl 2-(4-butoxy-3-formylphenyl)-4-methylthiazole-5-carboxylate | ethyl 2-(4-butoxy-3-formylphenyl)-4-methylthiazole-5-carboxylate is an impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: Ethyl 2-(4-butoxy-3-formylphenyl)-4-methylthiazole-5-carboxylate; A934076; Ethyl2-(4-butoxy-3-formylphenyl)-4-methylthiazole-5-carboxylate. CAS No. 2230270-03-6. Molecular formula: C18H21NO4S. Mole weight: 347.43. | |
| ethyl 2-(4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate | An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: 3-Descyano Febuxostat Ethyl Ester; Febuxostat Impurity F; 5-Thiazolecarboxylic acid, 4-methyl-2-[4-(2-methylpropoxy)phenyl]-, ethyl ester. Grades: 95% by HPLC. CAS No. 144060-97-9. Molecular formula: C17H21NO3S. Mole weight: 319.42. | |
| ethyl 2-(4-(sec-butoxy)-3-formylphenyl)-4-methylthiazole-5-carboxylate | ethyl 2-(4-(sec-butoxy)-3-formylphenyl)-4-methylthiazole-5-carboxylate is an impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. CAS No. 2375033-31-9. Molecular formula: C18H21NO4S. Mole weight: 347.43. | |
| Febuxostat | Febuxostat (TEI 6720) is a potent, selective and non-purine xanthine oxidase (XO) inhibitor with a K i value of 0.6 nM. Febuxostat has the potential for the research of hyperuricemia and gout [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TEI 6720; TMX 67. CAS No. 144060-53-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14268. | |
| Febuxostat | Xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. Group: Biochemicals. Alternative Names: 2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic Acid; 2-(3-Cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic Acid; TEI 6720; TMX 67. Grades: Highly Purified. CAS No. 144060-53-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Febuxostat 2-Butyl Isomer Ethyl Ester | Febuxostat 2-Butyl Isomer Ethyl Ester is an impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: Ethyl 2-(4-(sec-Butoxy)-3-cyanophenyl)-4-methylthiazole-5-carboxylate. CAS No. 2375033-35-3. Molecular formula: C18H20N2O3S. Mole weight: 344.43. | |
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