A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
25mg Pack Size. Group: Analytical Reagents, Bioactive Small Molecules, Biochemicals. Formula: C27H45NO2 ·HCl. CAS No. 6192-62-7. Prepack ID 10945566-25mg. Molecular Weight 452.11. See USA prepack pricing.
Tomatidine Hydrochloride
Tomatidine is a steroidal alkaloid found in the skins of unripe tomatoes. Structurally, Tomatidine resembles cylopamine, but does not inhibit the Hedgehog (Hh) signaling pathway. May be used as a negative control for Cyclopamine and KAAD-Cyclopamine. Group: Biochemicals. Alternative Names: 3b-Hydroxy-5a-tomatidane Hydrochloride, 5a-Tomatidan-3b-ol hydrochloride; (3 β,5α,22 β,25S)-Spirosolan-3-ol Hydrochloride. Grades: Highly Purified. CAS No. 6192-62-7. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Tomatine
Tomatine. Group: Biochemicals. CAS No. 17406-45-0. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Tomatine
Tomatine is a glycoalkaloid, found in the tomato plant ( Lycopersicon esculentum Mill.). Tomatine elicits neurotoxicity in RIP1 kinase and caspase-independent manner. Tomatine promotes the upregulation of nuclear apoptosis inducing factor (AIF) in neuroblastoma cells. Tomatine also inhibits 20S proteasome activity [1]. Uses: Scientific research. Group: Natural products. Alternative Names: α-Tomatine; Lycopersicin; Tomatin. CAS No. 17406-45-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N2166.
Tomatine (85%)
Tomatine is used as an antiproliferatice agent used in the suppression of breast adenocarcinoma cells. Group: Biochemicals. Alternative Names: (3 β,5α,22 β,25S)-Spirosolan-3-yl-O- β-D-glucopyranosyl-(1?2)-O-[ β-D-xylopyranosyl-(1?3)]-O- β-D-glucopyranosyl-(1?4)- β-D-galactopyranoside; α-Tomatine; Spiro[8H-naphth[2', 1':4, 5]indeno[2, 1-b]furan-8, 2'-piperidine] β-D-Galactopyranoside deriv.; Spirosolane β-D-Galactopyranoside deriv.; Lycopersicin; NSC 234440; NSC 9223. Grades: Highly Purified. CAS No. 17406-45-0. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
Tomatine (Lycopersicin)
Tomatine (Lycopersicin). Group: Biochemicals. Alternative Names: Lycopersicin. Grades: Plant Grade. CAS No. 17406-45-0. Pack Sizes: 10mg. Molecular Formula: C50H83NO21, Molecular Weight: 1034.2. US Biological Life Sciences.
Worldwide
Tomato extract
Tomato extract. Applications: Tomato extract(lycopene) can be used in functional food, drinks, health care products and pharmaceuticals. Group: Others. Purity: 1%, 5%, 6%, 10-98%lycopene. Appearance: Dark red powder. Source: Lycopene is a carotenoid that is found in red fruit and vegetables such as watermelons, grapefruits and tomatoes. Tomatoes and tomato products contain particularly high concentrations of lycopene. These super strength gelatin-free capsules contain 15mg of natural lycopene, are additive-free and are suitable for vegetarians and vegans. Tomato extract. Cat No: EXTC-132.
Tomato Extract Containing Lycopene
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Tomato Powder
Tomato powder by yesherb is derived from natural tomatoes. Tomato powder are widely known for their outstanding antioxidant content, including their oftentimes-rich concentration of lycopene. Intake of tomato powder has long been linked to heart health. Tomato powder has been shown to help lower total cholesterol, LDL cholesterol, and triglycerides. It is the elemental nutriment in human body with good physiological effect. Group: Others. Tomato Powder; Solanum Lycopersicum. Cat No: EXTC-105.
Tomaymycin
It is originally isolated from Str. achromogenes var. tomaymyceticus A-2127. Tomaymycin is resistant to gram-positive bacteria and fungi, and has a weak effect on E. coli. Synonyms: NSC 177499; 2-Ethylidene-1,2,3,10,11,11a-hexahydro-8-hydroxy-7,11-dimethoxy-5H-pyrrolo(2,1-c)(1,4)benzodiazepin-5-one. CAS No. 35050-55-6. Molecular formula: C16H20N2O4. Mole weight: 304.34.
Tomeglovir
Tomeglovir is a potent and selective inhibitor of cytomegalovirus (CMV) replication. Synonyms: BAY 38-4766; N-[4-[[5-(dimethylamino)naphthalen-1-yl]sulfonylamino]phenyl]-3-hydroxy-2,2-dimethylpropanamide. Grades: 99.45%. CAS No. 233254-24-5. Molecular formula: C23H27N3O4S. Mole weight: 441.54.
Tomicorat
Tomicorat is used as an anti-inflammatory agent. Uses: Tomicorat is used as an anti-inflammatory agent. Synonyms: 4-(5-((5-Fluoro-2-methylphenoxy)methyl)-2,2,4-trimethyl-1,2-dihydroquinolin-6-yl)-3-methoxyphenyl furan-2-carboxylate. Grades: >98 %. CAS No. 1027099-03-1. Molecular formula: C32H30FNO5. Mole weight: 527.59.
Tomivosertib
Tomivosertib (eFT508) is a potent, highly selective, and orally active MNK1 and MNK2 inhibitor, with IC 50 s of 1-2 nM against both isoforms. Tomivosertib (eFT508) treatment leads to a dose-dependent reduction in eIF4E phosphorylation at serine 209 (IC 50 =2-16 nM) in tumor cell lines [1]. Tomivosertib (eFT508) also dramatically downregulates PD-L1 protein abundance [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: eFT508. CAS No. 1849590-01-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100022.
Tonabersat (SB-220453) is a gap-junction modulator. Tonabersat prevents inflammatory damage in the central nervous system [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB-220453. CAS No. 175013-84-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15204.
Tonabersat.
Tonabersat. Group: Biochemicals. Alternative Names: N-[(3S,4S)-6-Acetyl-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-3-chloro-4-fluoro-benzamide; (3S-cis)-N-(6-acetyl-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl)-3-chloro-4-fluorobenzamide; SB 220453. Grades: Highly Purified. CAS No. 175013-84-0. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Tonabersat-d6
Tonabersat-d6. Group: Biochemicals. Alternative Names: N-[(3S,4S)-6-Acetyl-3,4-dihydro-3-hydroxy-2,2-(dimethyl-d6)-2H-1-benzopyran-4-yl]-3-chloro-4-fluorobenzamide; (3S-cis)-N-(6-acetyl-3,4-dihydro-3-hydroxy-2,2-(dimethyl-d6)-2H-1-benzopyran-4-yl)-3-chloro-4-fluorobenzamide; SB 220453-d6. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Tonalide
Used for non-alcoholic perfumes. Group: Biochemicals. Alternative Names: 1-(5,6,7,8-Tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthalenyl)-ethanone;5',6',7',8'-Tetrahydro-3',5',5',6',8',8'-hexamethyl-2'-acetonaphthone; AHMT (perfume); Extralide; Fixolide; NSC 19550. Grades: Highly Purified. CAS No. 21145-77-7. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Tonapofylline
Tonapofylline, a selective adenosine-1 receptor antagonist, has natriuretic effects and is able to maintain renal function, which can be beneficial to patients with congestive heart failure. Uses: Adenosine a1 receptor antagonists; adenosine a2b receptor antagonists. Synonyms: BG9928; BG-9928; BG 9928; Tonapofylline.3-(4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)bicyclo[2.2.2]octan-1-yl)propanoic acid. Grades: ≥98%. CAS No. 340021-17-2. Molecular formula: C22H32N4O4. Mole weight: 416.24.
Tongkat Ali Extract
Tongkat Ali Extract. Applications: Tongkat ali extract can be used in functional food, drinks, health care products and pharmaceuticals. Group: Others. Purity: 10:1, 100:1, 200:1 as required. Appearance: Brown powder. Tongkat Ali Extract. Cat No: EXTC-204.
Tonsil Microvascular Endothelial Cells, Human (Frozen)
Passage 3 cells are shipped in proliferating culture with a confluence of >90%. ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences.
Worldwide
Tonsil Microvascular Endothelial Cells, Human (T-25 flask)
Passage 3 cells are shipped in proliferating culture with a confluence of >90%. ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences.
Worldwide
TOOS (3-(N-Ethyl-3-methylanilino)-2-hydroxypropanesulfonic acid sodiumsalt)
1g Pack Size. Group: Analytical Reagents, Biochemicals, Stains & Indicators. Formula: C12H18NNaO4S. CAS No. 82692-93-1. Prepack ID 60478758-1g. Molecular Weight 295.33. See USA prepack pricing.
Toosendanin
Toosendanin, a triterpenoid extracted from the bark of fruit of Melia toosendan Sieb. et Zucc., possesses analgesic, insecticidal and anti-inflammatory activities [1]. Uses: Scientific research. Group: Natural products. CAS No. 58812-37-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0263.
Toosendanin
Toosendanin is a triterpenoid derivative, acts as a novel agonist of L-type Ca2+ channels in neonatal rat ventricular cells. Group: Biochemicals. Alternative Names: [C(R), 1α, 3α, 4 β, 5α, 7α, 12α, 13α, 14 β,15 β,17α]-3,12-Bis(acetyloxy)-14,15:21,23-diepoxy-1,7,19-trihydroxy-4,8-dimethyl-11-oxo-24-Norchola-20,22-diene-4-carboxaldehyde Cyclic 4,19-Hemiacetal; 14, 15-Epoxy-4, 10- (methanoxymethano) -1H-cyclopenta [a]phenanthrene, 24-Norchola-20,22-diene-4-carboxaldehyde Deriv.; 28-Deacetylsendanin; Chuanliansu. Grades: Highly Purified. CAS No. 58812-37-6. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Toosendanin (Chuanliansu, 12-Acetoxyamoorastatin)
Toosendanin (Chuanliansu, 12-Acetoxyamoorastatin). Group: Biochemicals. Alternative Names: Chuanliansu; 12-Acetoxyamoorastatin. Grades: Plant Grade. CAS No. 58812-37-6. Pack Sizes: 20mg. Molecular Formula: C30H38O11, Molecular Weight: 574.615999999999. US Biological Life Sciences.
Topiramate (McN 4853) is a broad-spectrum antiepileptic agent. Topiramate is a GluR5 receptor antagonist. Topiramate produces its antiepileptic effects through enhancement of GABAergic activity, inhibition of kainate/AMPA receptors, inhibition of voltage-sensitive sodium and calcium channels , increases in potassium conductance, and inhibition of carbonic anhydrase [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: McN 4853; RWJ 17021. CAS No. 97240-79-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0122.
One of the impurities of Topiramate, which is a fuctopyranose derivative and has been found to be used as an anticonvulsant agent. Synonyms: 2,3-O-(1-Methylethylidene)-b-D-fructopyranose 1-sulfamate Topiramate desacetal impurity. CAS No. 106881-41-8. Molecular formula: C9H17NO8S. Mole weight: 299.30.
Topiramate D-galactopyranose
Topiramate D-galactopyranose is a scientifically formulated pharmaceutical compound, used for studying epilepsy and migraine headaches. Marrying the prowess of anticonvulsant properties and the ability to curb repetitive neuronal firing, it exhibits a mechanism of action rooted in augmenting GABA receptor activity while diminishing glutamate receptor activity. Molecular formula: C18H31NO13S. Mole weight: 501.50.
Topiramate Didesacetal Impurity
One of the impurities of Topiramate, which is a fuctopyranose derivative and has been found to be used as an anticonvulsant agent. Synonyms: β-D-Fructopyranose 1-Sulfamate. CAS No. 106881-42-9. Molecular formula: C6H13NO8S. Mole weight: 259.24.
Topiramate Dimer Impurity
One of the impurities of Topiramate, which is a fuctopyranose derivative and has been found to be used as an anticonvulsant agent. Molecular formula: C24H39NO13S. Mole weight: 581.63.
Topiramate EP Impurity C
Topiramate EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 106881-41-8. Molecular formula: C9H17NO8S. Mole weight: 299.29. Catalog: APB106881418.
Topiramate Impurity 1
One of the impurities of Topiramate, which is a fuctopyranose derivative and has been found to be used as an anticonvulsant agent. Synonyms: 2,3. CAS No. 106881-35-0. Molecular formula: C12H19N3O8S. Mole weight: 365.36.
Topiramate Impurity 12
Topiramate Impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 106881-42-9. Molecular formula: C6H13NO8S. Mole weight: 259.23. Catalog: APB106881429.
Topiramate Impurity 16
Topiramate Impurity 16. Uses: For analytical and research use. Group: Impurity standards. CAS No. 10489-81-3. Molecular formula: C6H12O6. Mole weight: 180.16. Catalog: APB10489813.
Topiramate Impurity 2
One of the impurities of Topiramate, which is a fuctopyranose derivative and has been found to be used as an anticonvulsant agent. Synonyms: 4,5-O-(1-Methylethylidene)-b-D-fructopyranose 1-sulfamate. CAS No. 851957-35-2. Molecular formula: C9H17NO8S. Mole weight: 299.30.
Topiramate impurity B
Topiramate Impurity B is a pharmaceutical offering, aiding in anchoring the assessment of quality and purity within topiramate formulations, an eminent remedy for epilepsy research and migraine prophylaxis. Synonyms: Topiramate related compound B.
Topiramate impurity C
One of the impurities of Topiramate, which is a fuctopyranose derivative and has been found to be used as an anticonvulsant agent. Synonyms: (2,2,7,7-tetramethyl-tetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d] pyran-3a-yl)methyl sulfurochloridoate. Molecular formula: C12H19ClO8S. Mole weight: 358.79.
Topiramate Impurity D
Cas No. 25018-67-1.
Topiramate N-Methyl Impurity
One of the impurities of Topiramate, which is a fuctopyranose derivative and has been found to be used as an anticonvulsant agent. Synonyms: N-Methyl Topiramate; 2,3:4,5-bis-O-(1-Methylethylidene)-β-D-Fructopyranose 1-(N-Methylsulfamate); 2,3:4,5-bis-O-(1-methylethylidene)-β-D-fructopyranose Methylsulfamate. CAS No. 97240-80-7. Molecular formula: C13H23NO8S. Mole weight: 353.39.
Topiramate Related Compound A
One of the impurities of Topiramate, which is a fuctopyranose derivative and has been found to be used as an anticonvulsant agent. Synonyms: 2,3:4,5-Di-O-isopropylidene-β-D-fructopyranose; 2,3:4,5-Bis-O-(1-methylethylidene)-β-D-fructopyranose; USP Topiramate Related Compound A; Diacetonefructose; ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-3a-yl)methanol. Grades: ≥98%. CAS No. 20880-92-6. Molecular formula: C12H20O6. Mole weight: 260.28.
Topiramate Related Compound A
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Topiroxostat
Topiroxostat (FYX-051) is a potent and orally active xanthine oxidoreductase (XOR) inhibitor with an IC 50 value of 5.3 nM and a K i value of 5.7 nM. Topiroxostat exhibits weak CYP3A4 -inhibitory activity (18.6%). Topiroxostat has the potential for hyperuricemia treatment [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FYX-051. CAS No. 577778-58-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14874.
Topiroxostat
Topiroxostat is a novel and potent xanthine oxidoreductase (XOR) inhibitor. Uses: Enzyme inhibitors. Synonyms: FYX051; FYX051; FYX 051; Topiroxostat. trade names Topiloric Uriadec. Grades: >98%. CAS No. 577778-58-6. Molecular formula: C13H8N6. Mole weight: 248.24.
Topiroxostat Impurity 1
One of the impurities of Topiroxostat, which is a xanthine oxidase inhibitor and has been found to be effective in the treatment of gout and hyperuricemia. Synonyms: 4-(5-(Pyridin-4-yl)-1,3,4-oxadiazol-2-yl)picolinonitrile; 4-(5-pyridin-4-yl-1,3,4-oxadiazol-2-yl)pyridine-2-carbonitrile; TOPIROXOSTAT IMPURITY 1; DTXSID001166750; 2-Pyridinecarbonitrile, 4-[5-(4-pyridinyl)-1,3,4-oxadiazol-2-yl]-. Molecular formula: C7H10N6O. Mole weight: 194.2.
Topiroxostat Impurity 10
One of the impurities of Topiroxostat, which is a xanthine oxidase inhibitor and has been found to be effective in the treatment of gout and hyperuricemia. Molecular formula: C14H8N4O. Mole weight: 248.25.
Topiroxostat Impurity 11
One of the impurities of Topiroxostat, which is a xanthine oxidase inhibitor and has been found to be effective in the treatment of gout and hyperuricemia. Molecular formula: C14H6N6O. Mole weight: 274.24.
Topiroxostat Impurity 12
One of the impurities of Topiroxostat, which is a xanthine oxidase inhibitor and has been found to be effective in the treatment of gout and hyperuricemia. Molecular formula: C14H9N7O. Mole weight: 291.27.
Topiroxostat Impurity 13
One of the impurities of Topiroxostat, which is a xanthine oxidase inhibitor and has been found to be effective in the treatment of gout and hyperuricemia. Molecular formula: C14H7N7. Mole weight: 273.26.
Topiroxostat Impurity 2
One of the impurities of Topiroxostat, which is a xanthine oxidase inhibitor and has been found to be effective in the treatment of gout and hyperuricemia. Molecular formula: C7H8N4O2. Mole weight: 180.17.
Topiroxostat Impurity 3
One of the impurities of Topiroxostat, which is a xanthine oxidase inhibitor and has been found to be effective in the treatment of gout and hyperuricemia. Molecular formula: C6H7N3O2. Mole weight: 153.14.
Topiroxostat Impurity 4
One of the impurities of Topiroxostat, which is a xanthine oxidase inhibitor and has been found to be effective in the treatment of gout and hyperuricemia. Molecular formula: C12H9N5O. Mole weight: 239.24.
Topiroxostat Impurity 5
One of the impurities of Topiroxostat, which is a xanthine oxidase inhibitor and has been found to be effective in the treatment of gout and hyperuricemia. Synonyms: 4-Amino-3,5-bis(4-pyridyl)-1,2,4-triazole; 4,4'-(4-Amino-4H-1,2,4-triazole-3,5-diyl)di-pyridine; 3,5-Di-4-pyridinyl-4H-1,2,4-triazol-4-amine. CAS No. 38634-05-8. Molecular formula: C13H10N6O. Mole weight: 266.26.
Topiroxostat Impurity 6
One of the impurities of Topiroxostat, which is a xanthine oxidase inhibitor and has been found to be effective in the treatment of gout and hyperuricemia. Molecular formula: C13H9N5O2. Mole weight: 267.25.
Topiroxostat Impurity 7
One of the impurities of Topiroxostat, which is a xanthine oxidase inhibitor and has been found to be effective in the treatment of gout and hyperuricemia. Molecular formula: C20H2N10. Mole weight: 392.39.
Topiroxostat Impurity 9
One of the impurities of Topiroxostat, which is a xanthine oxidase inhibitor and has been found to be effective in the treatment of gout and hyperuricemia. Synonyms: Topiroxostat Impurity 9; 577778-82-6; 4-(5-(2-Cyanopyridin-4-yl)-1H-1,2,4-triazol-3-yl)pyridine 1-oxide; SCHEMBL4678077; 4-[5-(1-hydroxypyridin-4-ylidene)-1,2,4-triazol-3-yl]pyridine-2-carbonitrile. CAS No. 577778-82-6. Molecular formula: C13H8N6O. Mole weight: 264.25.
Topiroxostat Impurity C
One of the impurities of Topiroxostat, which is a xanthine oxidase inhibitor and has been found to be effective in the treatment of gout and hyperuricemia. Molecular formula: C13H7N5O. Mole weight: 249.23.
Topiroxostat Impurity F
One of the impurities of Topiroxostat, which is a xanthine oxidase inhibitor and has been found to be effective in the treatment of gout and hyperuricemia. Molecular formula: C12H11N5O2. Mole weight: 257.25.
Topiroxostat Impurity L
One of the impurities of Topiroxostat, which is a xanthine oxidase inhibitor and has been found to be effective in the treatment of gout and hyperuricemia. Molecular formula: C13H8N6O. Mole weight: 264.25.
recombinant, expressed in insect cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
Topo I (C651-765) (C terminal domain) human
recombinant, expressed in insect cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
Topo I (N1-197) (NTD) human
recombinant, expressed in insect cells, ?85% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
Topoisomerase I from E. coli, Recombinant
Topoisomerase I relaxes supercoiled DNA molecules. The enzyme initiates transient breakages and rejoins of phosphodiester bonds in superhelical turns of closed-circular DNA. Enzyme activity is independent of right-and left-handed superhelices. Topoisomerase i (e. coli) catalyzes the relaxation of negatively supercoiled dna. topoisomerase i has also been implicated in knotting and unknotting dna and in linking complementary rings of single-stranded dna into double-stranded rings. the intact holoenzyme is a 97 kda protein. Group: Enzymes. Synonyms: Topoisomerase I; EC 5.99.1.2; type I DNA topoisomerase; untwisting enzyme; relaxing enzyme; nicking-closing enzyme; swivelase; ω-protein; deoxyribonucleate topoisomerase; topoisomerase; type I DNA topoisomerase; DNA topoisomerase; TOPO I. TOPO I. Storage: at -20°C. Form: 50 mM KCl, 10 mM Tris-HCl (pH 7.5), 35 mM (NH4)2SO4, 0.1 mM EDTA, 1 mM DTT and 50% glycerol. Source: E. coli. Species: E. coli. Topoisomerase I; EC 5.99.1.2; type I DNA topoisomerase; untwisting enzyme; relaxing enzyme; nicking-closing enzyme; swivelase; ω-protein; deoxyribonucleate topoisomerase; topoisomerase; type I DNA topoisomerase; DNA topoisomerase; TOPO I. Cat No: NATE-1339.
Topoisomerase I from Human, Recombinant
Topoisomerase I relaxes supercoiled DNA molecules. The enzyme initiates transient breakages and rejoins of phosphodiester bonds in superhelical turns of closed-circular DNA. Enzyme activity is independent of right-and left-handed superhelices. Group: Enzymes. Synonyms: Topoisomerase I; EC 5.99.1.2; type I DNA topoisomerase; untwisting enzyme; relaxing enzyme; nicking-closing enzyme; swivelase; ω-protein; deoxyribonucleate topoisomerase; topoisomerase; type I DNA topoisomerase; DNA topoisomerase; TOPO I. TOPO I. Stability: Stable for 3 months undiluted. Storage: Store at -80°C. It is recommended that the enzyme is aliquoted to avoid repeated freeze-thaw cycles. Source: Baculovirus-infected insect cells (Spodoptera frugiperda). Species: Human. Topoisomerase I; EC 5.99.1.2; type I DNA topoisomerase; untwisting enzyme; relaxing enzyme; nicking-closing enzyme; swivelase; ω-protein; deoxyribonucleate topoisomerase; topoisomerase; type I DNA topoisomerase; DNA topoisomerase; TOPO I. Cat No: NATE-1340.
Topoisomerase II-alpha-b (828-836)
Topoisomerase II-alpha-b (828-836) is a peptide derived from Topoisomerase II-alpha-b. Topoisomerase II-alpha is an enzyme that controls and alters the topologic states of DNA during transcription. Human topoisomerase II enzymes are targets for a number of widely used anticancer agents.