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| Product | Description | |
|---|---|---|
| tRNA (adenine22-N1)-methyltransferase | The enzyme specifically methylates adenine22 in tRNA. Group: Enzymes. Synonyms: TrmK; YqfN; Sp1610 (gene name); tRNA: m1A22 methyltransferase. Enzyme Commission Number: EC 2.1.1.217. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1819; tRNA (adenine22-N1)-methyltransferase; EC 2.1.1.217; TrmK; YqfN; Sp1610 (gene name); tRNA: m1A22 methyltransferase. Cat No: EXWM-1819. |  |
| tRNA(adenine34) deaminase | The enzyme is involved in editing of tRNA. The active site contains Zn2+. Group: Enzymes. Synonyms: tRNA:A34 deaminase; tadA protein; ADAT2-ADAT3 complex; TADA; tRNA adenosine deaminase arginine; AtTadA; tadA/ecADAT2; tRNA A:34 deaminase. Enzyme Commission Number: EC 3.5.4.33. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4561; tRNA(adenine34) deaminase; EC 3.5.4.33; tRNA:A34 deaminase; tadA protein; ADAT2-ADAT3 complex; TADA; tRNA adenosine deaminase arginine; AtTadA; tadA/ecADAT2; tRNA A:34 deaminase. Cat No: EXWM-4561. | |
| tRNA (adenine57-N1/adenine58-N1)-methyltransferase | The enzyme catalyses the formation of N1-methyladenine at two adjacent positions (57 and 58) in the T-loop of certain tRNAs (e.g. tRNAAsp). Methyladenosine at position 57 is an obligatory intermediate for the synthesis of methylinosine, which is commonly found at position 57 of archaeal tRNAs. Group: Enzymes. Synonyms: TrmI; PabTrmI; AqTrmI; MtTrmI. Enzyme Commission Number: EC 2.1.1.219. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1821; tRNA (adenine57-N1/adenine58-N1)-methyltransferase; EC 2.1.1.219; TrmI; PabTrmI; AqTrmI; MtTrmI. Cat No: EXWM-1821. | |
| tRNA (adenine58-N1)-methyltransferase | The enzyme specifically methylates adenine58 in tRNA. The methylation of A58 is critical for maintaining the stability of initiator tRNAMet in yeast. Group: Enzymes. Synonyms: tRNA m1A58 methyltransferase; tRNA (m1A58) methyltransferase; TrmI; tRNA (m1A58) Mtase; Rv2118cp; Gcd10p-Gcd14p; Trm61p-Trm6p. Enzyme Commission Number: EC 2.1.1.220. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1823; tRNA (adenine58-N1)-methyltransferase; EC 2.1.1.220; tRNA m1A58 methyltransferase; tRNA (m1A58) methyltransferase; TrmI; tRNA (m1A58) Mtase; Rv2118cp; Gcd10p-Gcd14p; Trm61p-Trm6p. Cat No: EXWM-1823. | |
| tRNA (adenine9-N1)-methyltransferase | The enzyme from Sulfolobus acidocaldarius specifically methylates adenine9 in tRNA. The bifunctional enzyme from Thermococcus kodakaraensis also catalyses the methylation of guanine9 in tRNA (cf. EC 2.1.1.221, tRNA (guanine9-N1)-methyltransferase). Group: Enzymes. Synonyms: Trm10p (ambiguous); tRNA(m1G9/m1A9)-methyltransferase; tRNA(m1G9/m1A9)MTase; TK0422p (gene name); tRNA m1A9-methyltransferase; tRNA m1A9 Mtase. Enzyme Commission Number: EC 2.1.1.218. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1820; tRNA (adenine9-N1)-methyltransferase; EC 2.1.1.218; Trm10p (ambiguous); tRNA(m1G9/m1A9)-methyltransferase; tRNA(m1G9/m1A9)MTase; TK0422p (gene name); tRNA m1A9-methyltransferase; tRNA m1A9 Mtase. Cat No: EXWM-1820. | |
| tRNA (adenine-N6-)-methyltransferase | This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. Group: Enzymes. Synonyms: S-adenosyl-L-methionine:tRNA (adenine-6-N-)-methyltransferase. Enzyme Commission Number: EC 2.1.1.55. CAS No. 9014-53-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1957; tRNA (adenine-N6-)-methyltransferase; EC 2.1.1.55; 9014-53-3; S-adenosyl-L-methionine:tRNA (adenine-6-N-)-methyltransferase. Cat No: EXWM-1957. | |
| tRNAAla(adenine37) deaminase | The enzyme deaminates adenosine37 to inosine in eukaryotic tRNAAla. tRNA editing is strictly dependent on Mg2+. Group: Enzymes. Synonyms: ADAT1; Tad1p. Enzyme Commission Number: EC 3.5.4.34. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4562; tRNAAla(adenine37) deaminase; EC 3.5.4.34; ADAT1; Tad1p. Cat No: EXWM-4562. | |
| tRNA (carboxymethyluridine34-5-O)-methyltransferase | The enzyme catalyses the posttranslational modification of uridine residues at the wobble position 34 of the anticodon loop of tRNA. Group: Enzymes. Synonyms: ALKBH8; ABH8; Trm9; tRNA methyltransferase 9. Enzyme Commission Number: EC 2.1.1.229. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1832; tRNA (carboxymethyluridine34-5-O)-methyltransferase; EC 2.1.1.229; ALKBH8; ABH8; Trm9; tRNA methyltransferase 9. Cat No: EXWM-1832. | |
| tRNA (cytidine32/guanosine34-2'-O)-methyltransferase | The enzyme from Saccharomyces cerevisiae catalyses the formation of 2'-O-methylnucleotides at positions 32 and 34 of the yeast tRNAPhe, tRNATrp and, possibly, tRNALeu. Group: Enzymes. Synonyms: Trm7p. Enzyme Commission Number: EC 2.1.1.205. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1806; tRNA (cytidine32/guanosine34-2'-O)-methyltransferase; EC 2.1.1.205; Trm7p. Cat No: EXWM-1806. | |
| tRNA (cytidine32/uridine32-2'-O)-methyltransferase | In Escherichia coli YfhQ is the only methyltransferase responsible for the formation of 2'-O-methylcytidine32 in tRNA. No methylation of cytosine34 in tRNALeu(CAA). In vitro the enzyme 2-O-methylates cytidine32 of tRNASer1 and uridine32 of tRNAGln2. Group: Enzymes. Synonyms: YfhQ; tRNA:Cm32/Um32 methyltransferase; TrMet(Xm32); TrmJ. Enzyme Commission Number: EC 2.1.1.200. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1801; tRNA (cytidine32/uridine32-2'-O)-methyltransferase; EC 2.1.1.200; YfhQ; tRNA:Cm32/Um32 methyltransferase; TrMet(Xm32); TrmJ. Cat No: EXWM-1801. | |
| tRNA (cytidine34-2'-O)-methyltransferase | The enzyme from Escherichia coli catalyses the 2'-O-methylation of cytidine or 5-carboxymethylaminomethyluridine at the wobble position at nucleotide 34 in tRNALeuCmAA and tRNALeucmnm5UmAA. The enzyme is selective for the two tRNALeu isoacceptors and only methylates these when they present the correct anticodon loop sequence and modification pattern. Specifically, YibK requires a pyrimidine nucleoside at position 34, it has a clear preference for an adenosine at position 35, and it fails to methylate without prior addition of the N6-(isopentenyl)-2-methylthioadenosine modification at position 37. Group: Enzymes. Synonyms: yibK (gene name); methyltransferase yibK; TrmL; tRNA methyltransferase L; tRNA (cytidine34/5-carboxymethylaminomethyluridine34-2'-O)-methyltransferase. Enzyme Commission Number: EC 2.1.1.207. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1808; tRNA (cytidine34-2'-O)-methyltransferase; EC 2.1.1.207; yibK (gene name); methyltransferase yibK; TrmL; tRNA methyltransferase L; tRNA (cytidine34/5-carboxymethylaminomethyluridine34-2'-O)-methyltransferase. Cat No: EXWM-1808. | |
| tRNA (cytidine56-2'-O)-methyltransferase | The archaeal enzyme specifically catalyses the S-adenosyl-L-methionine dependent 2'-O-ribose methylation of cytidine at position 56 in tRNA transcripts. Group: Enzymes. Synonyms: aTrm56; tRNA ribose 2'-O-methyltransferase aTrm56; PAB1040 (gene name). Enzyme Commission Number: EC 2.1.1.206. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1807; tRNA (cytidine56-2'-O)-methyltransferase; EC 2.1.1.206; aTrm56; tRNA ribose 2'-O-methyltransferase aTrm56; PAB1040 (gene name). Cat No: EXWM-1807. | |
| tRNA (cytosine34-C5)-methyltransferase | The human enzyme is specific for C5-methylation of cytosine34 in tRNA precursors. The intron in the human pre-tRNALeu(CAA) is indispensable for the C5-methylation of cytosine in the first position of the anticodon. It is not able to form 5-methylcytosine at positions 48 and 49 of human and yeast tRNA precursors. Group: Enzymes. Synonyms: hTrm4 Mtase; hTrm4 methyltransferase; hTrm4 (gene name); tRNA:m5C-methyltransferase (ambiguous). Enzyme Commission Number: EC 2.1.1.203. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1804; tRNA (cytosine34-C5)-methyltransferase; EC 2.1.1.203; hTrm4 Mtase; hTrm4 methyltransferase; hTrm4 (gene name); tRNA:m5C-methyltransferase (ambiguous). Cat No: EXWM-1804. | |
| tRNA (cytosine38-C5)-methyltransferase | The eukaryotic enzyme catalyses methylation of cytosine38 in the anti-codon loop of tRNAAsp(GTC), tRNAVal(AAC) and tRNAGly(GCC). Methylation by Dnmt2 protects tRNAs against stress-induced cleavage by ribonuclease. Group: Enzymes. Synonyms: hDNMT2 (gene name); DNMT2 (gene name); TRDMT1 (gene name). Enzyme Commission Number: EC 2.1.1.204. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1805; tRNA (cytosine38-C5)-methyltransferase; EC 2.1.1.204; hDNMT2 (gene name); DNMT2 (gene name); TRDMT1 (gene name). Cat No: EXWM-1805. | |
| tRNA(cytosine8) deaminase | The enzyme from Methanopyrus kandleri specifically catalyses the deamimation of cytosine at poition 8 of tRNA in 30 different tRNAs. This cytosine-to-uracil editing guarantees the proper folding and functionality of the tRNAs. Group: Enzymes. Synonyms: CDAT8. Enzyme Commission Number: EC 3.5.4.35. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4563; tRNA(cytosine8) deaminase; EC 3.5.4.35; CDAT8. Cat No: EXWM-4563. | |
| tRNA-dihydrouridine16/17 synthase [NAD(P)+] | A flavoprotein. The enzyme specifically modifies uracil16 and uracil17 in tRNA. Group: Enzymes. Synonyms: Dus1p; tRNA-dihydrouridine synthase 1. Enzyme Commission Number: EC 1.3.1.88. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1357; tRNA-dihydrouridine16/17 synthase [NAD(P)+]; EC 1.3.1.88; Dus1p; tRNA-dihydrouridine synthase 1. Cat No: EXWM-1357. | |
| tRNA-dihydrouridine20a/20b synthase [NAD(P)+] | A flavoenzyme. The enzyme specifically modifies uracil20a and uracil20b in tRNA. Group: Enzymes. Synonyms: Dus4p. Enzyme Commission Number: EC 1.3.1.90. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1360; tRNA-dihydrouridine20a/20b synthase [NAD(P)+]; EC 1.3.1.90; Dus4p. Cat No: EXWM-1360. | |
| tRNA-dihydrouridine20 synthase [NAD(P)+] | A flavoenzyme. The enzyme specifically modifies uracil20 in tRNA. Group: Enzymes. Synonyms: Dus2p; tRNA-dihydrouridine synthase 2. Enzyme Commission Number: EC 1.3.1.91. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1361; tRNA-dihydrouridine20 synthase [NAD(P)+]; EC 1.3.1.91; Dus2p; tRNA-dihydrouridine synthase 2. Cat No: EXWM-1361. | |
| tRNA-dihydrouridine47 synthase [NAD(P)+] | A flavoenzyme. The enzyme specifically modifies uracil47 in tRNA. Group: Enzymes. Synonyms: Dus3p; tRNA-dihydrouridine synthase 3. Enzyme Commission Number: EC 1.3.1.89. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1358; tRNA-dihydrouridine47 synthase [NAD(P)+]; EC 1.3.1.89; Dus3p; tRNA-dihydrouridine synthase 3. Cat No: EXWM-1358. | |
| tRNA dimethylallyltransferase | Formerly known as tRNA isopentenyltransferase (EC 2.5.1.8), but it is now known that dimethylallyl diphosphate, rather than isopentenyl diphosphate, is the substrate. Group: Enzymes. Synonyms: tRNA prenyltransferase; MiaA; transfer ribonucleate isopentenyltransferase (incorrect); Δ2-isopentenyl pyrophosphate:tRNA-Δ2-isopentenyl transferase (incorrect); Δ2-isopentenyl pyrophosphate:transfer ribonucleic acid Δ2-isopentenyltransferase (incorrect); dimethylallyl-diphosphate: tRNA dimethylallyltransferase. Enzyme Commission Number: EC 2.5.1.75. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2813; tRNA dimethylallyltransferase; EC 2.5.1.75; tRNA prenyltransferase; MiaA; transfer ribonucleate isopentenyltransferase (incorrect); Δ2-isopentenyl pyrophosphate:tRNA-Δ2-isopentenyl transferase (incorrect); Δ2-isopentenyl pyrophosphate:transfer ribonucleic acid Δ2-isopentenyltransferase (incorrect); dimethylallyl-diphosphate: tRNA dimethylallyltransferase. Cat No: EXWM-2813. | |
| tRNA (guanine10-N2)-dimethyltransferase | TRNA (guanine10-N2)-dimethyltransferase (EC 2.1.1.213, PAB1283, N(2),N(2)-dimethylguanosine tRNA methyltransferase, Trm-G10, PabTrm-G10, PabTrm-m2 2G10 enzyme) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (guanine10-N2)-dimethyltransferase. Group: Enzymes. Synonyms: PAB1283; N(2),N(2)-dimethylguanosine tRNA methyltransferase; Trm-G10; PabTrm-G10; PabTrm-m2 2G10 enzyme. Enzyme Commission Number: EC 2.1.1.213. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1815; tRNA (guanine10-N2)-dimethyltransferase; EC 2.1.1.213; PAB1283; N(2),N(2)-dimethylguanosine tRNA methyltransferase; Trm-G10; PabTrm-G10; PabTrm-m2 2G10 enzyme. Cat No: EXWM-1815. | |
| tRNA (guanine10-N2)-methyltransferase | In contrast to the archaeal enzyme tRNA (guanine10-N2)-dimethyltransferase (EC 2.1.1.213), tRNA (guanine10-N2)-methyltransferase from yeast does not catalyse the methylation from N2-methylguanine10 to N2-dimethylguanine10 in tRNA. Group: Enzymes. Synonyms: (m2G10) methyltransferase; Trm11-Trm112 complex. Enzyme Commission Number: EC 2.1.1.214. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1816; tRNA (guanine10-N2)-methyltransferase; EC 2.1.1.214; (m2G10) methyltransferase; Trm11-Trm112 complex. Cat No: EXWM-1816. | |
| tRNA-guanine15 transglycosylase | Archaeal tRNAs contain the modified nucleoside archaeosine at position 15. This archaeal enzyme catalyses the exchange of guanine at position 15 of tRNA with the base preQ0, which is ultimately modified to form the nucleoside archaeosine (cf. EC 2.6.1.97). Group: Enzymes. Synonyms: tRNA transglycosylase (ambiguous); transfer ribonucleate glycosyltransferase (ambiguous); tRNA guanine15 transglycosidase; TGT (ambiguous); transfer ribonucleic acid guanine15 transglycosylase. Enzyme Commission Number: EC 2.4.2.48. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2677; tRNA-guanine15 transglycosylase; EC 2.4.2.48; tRNA transglycosylase (ambiguous); transfer ribonucleate glycosyltransferase (ambiguous); tRNA guanine15 transglycosidase; TGT (ambiguous); transfer ribonucleic acid guanine15 transglycosylase. Cat No: EXWM-2677. | |
| tRNA (guanine26-N2)-dimethyltransferase | The enzyme dissociates from its tRNA substrate between the two consecutive methylation reactions. In contrast to EC 2.1.1.215, tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase, this enzyme does not catalyse the methylation of guanine27 in tRNA. Group: Enzymes. Synonyms: Trm1p; TRM1; tRNA (m22G26)dimethyltransferase. Enzyme Commission Number: EC 2.1.1.216. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1818; tRNA (guanine26-N2)-dimethyltransferase; EC 2.1.1.216; Trm1p; TRM1; tRNA (m22G26)dimethyltransferase. Cat No: EXWM-1818. | |
| tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase | The enzyme from Aquifex aeolicus is similar to the TRM1 methyltransferases of archaea and eukarya (see EC 2.1.1.216, tRNA (guanine26-N2)-dimethyltransferase). However, it catalyses the double methylation of guanines at both positions 26 and 27 of tRNA. Group: Enzymes. Synonyms: Trm1 (ambiguous); tRNA (N2,N2-guanine)-dimethyltransferase; tRNA (m2(2G26) methyltransferase; Trm1[tRNA (m2(2)G26) methyltransferase]. Enzyme Commission Number: EC 2.1.1.215. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1817; tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase; EC 2.1.1.215; Trm1 (ambiguous); tRNA (N2,N2-guanine)-dimethyltransferase; tRNA (m2(2G26) methyltransferase; Trm1[tRNA (m2(2)G26) methyltransferase]. Cat No: EXWM-1817. | |
| tRNA (guanine37-N1)-methyltransferase | This enzyme is important for the maintenance of the correct reading frame during translation. Unlike TrmD from Escherichia coli, which recognizes the G36pG37 motif preferentially, the human enzyme (encoded by TRMT5) also methylates inosine at position 37. Group: Enzymes. Synonyms: TrmD; tRNA (m1G37) methyltransferase; transfer RNA (m1G37) methyltransferase; Trm5p; TRMT5; tRNA-(N1G37) methyltransferase; MJ0883 (gene name). Enzyme Commission Number: EC 2.1.1.228. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1831; tRNA (guanine37-N1)-methyltransferase; EC 2.1.1.228; TrmD; tRNA (m1G37) methyltransferase; transfer RNA (m1G37) methyltransferase; Trm5p; TRMT5; tRNA-(N1G37) methyltransferase; MJ0883 (gene name). Cat No: EXWM-1831. | |
| tRNA (guanine46-N7)-methyltransferase | The enzyme specifically methylates guanine46 at N7 in tRNA. Group: Enzymes. Synonyms: Trm8/Trm82; TrmB; tRNA (m7G46) methyltransferase; transfer ribonucleate guanine 7-methyltransferase; 7-methylguanine transfer ribonucleate methylase; tRNA guanine 7-methyltransferase; N7-methylguanine methylase; S-adenosyl-L-methionine:tRNA (guanine-7-N-)-methyltransferase. Enzyme Commission Number: EC 2.1.1.33. CAS No. 37257-00-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1937; tRNA (guanine46-N7)-methyltransferase; EC 2.1.1.33; 37257-00-4; Trm8/Trm82; TrmB; tRNA (m7G46) methyltransferase; transfer ribonucleate guanine 7-methyltransferase; 7-methylguanine transfer ribonucleate methylase; tRNA guanine 7-methyltransferase; N7-methylguanine methylase; S-adenosyl-L-methionine:tRNA (guanine-7-N-)-methyltransferase. Cat No: EXWM-1937. | |
| tRNA (guanine6-N2)-methyltransferase | The enzyme specifically methylates guanine6 at N2 in tRNA. Group: Enzymes. Synonyms: methyltransferase Trm14; m2G6 methyltransferase. Enzyme Commission Number: EC 2.1.1.256. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1860; tRNA (guanine6-N2)-methyltransferase; EC 2.1.1.256; methyltransferase Trm14; m2G6 methyltransferase. Cat No: EXWM-1860. | |
| tRNA (guanine9-N1)-methyltransferase | The enzyme from Saccharomyces cerevisiae specifically methylates guanine9. The bifunctional enzyme from Thermococcus kodakaraensis also catalyses the methylation of adenine9 in tRNA (cf. EC 2.1.1.218, tRNA (adenine9-N1)-methyltransferase). Group: Enzymes. Synonyms: Trm10p (ambiguous); tRNA(m1G9/m1A9)-methyltransferase; tRNA(m1G9/m1A9)MTase; tRNA (guanine-N(1)-)-methyltransferase; tRNA m1G9-methyltransferase; tRNA m1G9 MTase. Enzyme Commission Number: EC 2.1.1.221. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1824; tRNA (guanine9-N1)-methyltransferase; EC 2.1.1.221; Trm10p (ambiguous); tRNA(m1G9/m1A9)-methyltransferase; tRNA(m1G9/m1A9)MTase; tRNA (guanine-N(1)-)-methyltransferase; tRNA m1G9-methyltransferase; tRNA m1G9 MTase. Cat No: EXWM-1824. | |
| tRNA (guanosine18-2'-O)-methyltransferase | The enzyme catalyses the methylation of guanosine18 in tRNA. Group: Enzymes. Synonyms: tRNA (Gm18) 2'-O-methyltransferase; tRNA (Gm18) methyltransferase; TrmH; SpoU. Enzyme Commission Number: EC 2.1.1.34. CAS No. 37257-01-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1938; tRNA (guanosine18-2'-O)-methyltransferase; EC 2.1.1.34; 37257-01-5; tRNA (Gm18) 2'-O-methyltransferase; tRNA (Gm18) methyltransferase; TrmH; SpoU. Cat No: EXWM-1938. | |
| tRNA-guanosine34 transglycosylase | Certain prokaryotic and eukaryotic tRNAs contain the modified base queuine at position 34. In eukaryotes queuine is salvaged from food and incorporated into tRNA directly via a base-exchange reaction, replacing guanine. In eubacteria, which produce queuine de novo, the enzyme catalyses the exchange of guanine with the queuine precursor preQ1, which is ultimately modified to queuosine. The eubacterial enzyme can also use an earlier intermediate, preQ0, to replace guanine in unmodified tRNATyr and tRNAAsn. This enzyme acts after EC 1.7.1.13, preQ1 synthase, in the queuine-biosynthesis pathway. Group: Enzymes. Synonyms: guanine insertion enzyme (ambiguous); tRNA transglycosylase (ambiguou. Enzyme Commission Number: EC 2.4.2.29. CAS No. 72162-89-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2656; tRNA-guanosine34 transglycosylase; EC 2.4.2.29; 72162-89-1; guanine insertion enzyme (ambiguous); tRNA transglycosylase (ambiguous); Q-insertase (ambiguous); queuine34 transfer ribonucleate ribosyltransferase; transfer ribonucleate glycosyltransferase (ambiguous); tRNA guanine34 transglycosidase; queuine tRNA-ribosyltransferase (ambiguous); TGT; [tRNA]-guanine34:queuine tRNA-D-ribosyltransferase; transfer ribonucleic acid guanine34 transglycosylase. Cat No: EXWM-2656. | |
| tRNAHis guanylyltransferase | In eukarya an additional guanosine residue is added post-transcriptionally to the 5'-end of tRNAHis molecules. The addition occurs opposite a universally conserved adenosine73 and is thus the result of a non-templated 3'-5' addition reaction. The additional guanosine residue is an important determinant for aminoacylation by EC 6.1.1.21, histidyl-tRNA ligase.The enzyme requires a divalent cation for activity. ATP activation is not required when the substrate contains a 5'-triphosphate (ppp-tRNAHis). Group: Enzymes. Synonyms: histidine tRNA guanylyltransferase; Thg1p (ambiguous); Thg1 (ambiguous). Enzyme Commission Number: EC 2.7.7.79. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3291; tRNAHis guanylyltransferase; EC 2.7.7.79; histidine tRNA guanylyltransferase; Thg1p (ambiguous); Thg1 (ambiguous). Cat No: EXWM-3291. | |
| tRNAIle2-agmatinylcytidine synthase | The enzyme from the archaeon Archaeoglobus fulgidus modifies the wobble base of the CAU anticodon of the archaeal tRNAIle2 at the oxo group in position 2 of cytidine34. This modification is crucial for accurate decoding of the genetic code. In bacteria EC 6.3.4.19, tRNAIle-lysidine synthase, catalyses the modification of [tRNAIle2]-cytidine34 to [tRNAIle2]-lysidine34. Group: Enzymes. Synonyms: TiaS; AF2259; tRNAIle-2-agmatinylcytidine synthetase; tRNAIle-agm2C synthetase; tRNAIle-agmatidine synthetase. Enzyme Commission Number: EC 6.3.4.22. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5792; tRNAIle2-agmatinylcytidine synthase; EC 6.3.4.22; TiaS; AF2259; tRNAIle-2-agmatinylcytidine synthetase; tRNAIle-agm2C synthetase; tRNAIle-agmatidine synthetase. Cat No: EXWM-5792. | |
| tRNAIle-lysidine synthase | The bacterial enzyme modifies the wobble base of the CAU anticodon of tRNAIle at the oxo group in position 2 of cytidine34. This modification determines both codon and amino acid specificities of tRNAIle. Group: Enzymes. Synonyms: TilS; mesJ (gene name); yacA (gene name); isoleucine-specific transfer ribonucleate lysidine synthetase; tRNAIle-lysidine synthetase. Enzyme Commission Number: EC 6.3.4.19. CAS No. 635304-92-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5788; tRNAIle-lysidine synthase; EC 6.3.4.19; 635304-92-6; TilS; mesJ (gene name); yacA (gene name); isoleucine-specific transfer ribonucleate lysidine synthetase; tRNAIle-lysidine synthetase. Cat No: EXWM-5788. | |
| tRNA-intron lyase | The enzyme catalyses the final stage in the maturation of tRNA molecules. Group: Enzymes. Synonyms: transfer ribonucleate intron endoribonuclease; tRNA splicing endonuclease; splicing endonuclease; tRNATRPintron endonuclease; transfer splicing endonuclease. Enzyme Commission Number: EC 4.6.1.16. CAS No. 117444-13-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5353; tRNA-intron lyase; EC 4.6.1.16; 117444-13-0; transfer ribonucleate intron endoribonuclease; tRNA splicing endonuclease; splicing endonuclease; tRNATRPintron endonuclease; transfer splicing endonuclease. Cat No: EXWM-5353. | |
| tRNA:m4X modification enzyme | The enzyme from Saccharomyces cerevisiae 2'-O-methylates cytidine4 in tRNAPro and tRNAGly(GCC), and adenosine4 in tRNAHis. Group: Enzymes. Synonyms: TRM13; Trm13p; tRNA:Xm4 modification enzyme. Enzyme Commission Number: EC 2.1.1.225. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1828; tRNA:m4X modification enzyme; EC 2.1.1.225; TRM13; Trm13p; tRNA:Xm4 modification enzyme. Cat No: EXWM-1828. | |
| tRNAMet cytidine acetyltransferase | The enzyme acetylates the wobble base cytidine34 of the CAU anticodon of elongation-specific tRNAMet. Escherichia coli TmcA strictly discriminates elongator tRNAMet from tRNAIle, which is structurally similar and has the same anticodon loop, mainly by recognizing the C27-G43 pair in the anticodon stem. The enzyme can use GTP in place of ATP for formation of N4-acetylcytidine. Group: Enzymes. Synonyms: YpfI; TmcA. Enzyme Commission Number: EC 2.3.1.193. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2136; tRNAMet cytidine acetyltransferase; EC 2.3.1.193; YpfI; TmcA. Cat No: EXWM-2136. | |
| tRNA (N6-L-threonylcarbamoyladenosine37-C2)-methylthiotransferase | The enzyme, which is a member of the S-adenosyl-L-methionine-dependent radical (radical AdoMet) enzymes superfamily, binds two [4Fe-4S] clusters as well as the transferred sulfur. The sulfur donor is believed to be one of the [4Fe-4S] clusters, which is sacrificed in the process, so that in vitro the reaction is a single turnover. The identity of the electron donor is not known. Group: Enzymes. Synonyms: MtaB; methylthio-threonylcarbamoyl-adenosine transferase B; CDKAL1 (gene name). Enzyme Commission Number: EC 2.8.4.5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3431; tRNA (N6-L-threonylcarbamoyladenosine37-C2)-methylthiotransferase; EC 2.8.4.5; MtaB; methylthio-threonylcarbamoyl-adenosine transferase B; CDKAL1 (gene name). Cat No: EXWM-3431. | |
| tRNA nucleotidyltransferase | Brings about the final exonucleolytic trimming of the 3'-terminus of tRNA precursors in Escherichia coli by a phosphorolysis, producing a mature 3'-terminus on tRNA and nucleoside diphosphate. Not identical with EC 2.7.7.8 polyribonucleotide nucleotidyltransferase. Group: Enzymes. Synonyms: phosphate-dependent exonuclease; RNase PH; ribonuclease PH. Enzyme Commission Number: EC 2.7.7.56. CAS No. 116412-36-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3267; tRNA nucleotidyltransferase; EC 2.7.7.56; 116412-36-3; phosphate-dependent exonuclease; RNase PH; ribonuclease PH. Cat No: EXWM-3267. | |
| tRNAPhe (4-demethylwyosine37-C7) aminocarboxypropyltransferase | The enzyme, which is found in all eukaryotes and in the majority of Euryarchaeota (but not in the Crenarchaeota), is involved in the hypermodification of the guanine nucleoside at position 37 of tRNA leading to formation of assorted wye bases. This modification is essential for translational reading-frame maintenance. The eukaryotic enzyme is involved in biosynthesis of the tricyclic base wybutosine, which is found only in tRNAPhe. Group: Enzymes. Synonyms: TYW2; tRNA-yW synthesizing enzyme-2; TRM12 (gene name); taw2 (gene name). Enzyme Commission Number: EC 2.5.1.114. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2730; tRNAPhe (4-demethylwyosine37-C7) aminocarboxypropyltransferase; EC 2.5.1.114; TYW2; tRNA-yW synthesizing enzyme-2; TRM12 (gene name); taw2 (gene name). Cat No: EXWM-2730. | |
| tRNAPhe 7-[(3-amino-3-carboxypropyl)-4-demethylwyosine37-N4]-methyltransferase | The enzyme is involved in the biosynthesis of hypermodified tricyclic bases found at position 37 of certain tRNAs. These modifications are important for translational reading-frame maintenance. The enzyme is found in all eukaryotes and in some archaea, but not in bacteria. The eukaryotic enzyme is involved in the biosynthesis of wybutosine. Group: Enzymes. Synonyms: TYW3 (gene name); tRNA-yW synthesizing enzyme-3. Enzyme Commission Number: EC 2.1.1.282. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1889; tRNAPhe 7-[(3-amino-3-carboxypropyl)-4-demethylwyosine37-N4]-methyltransferase; EC 2.1.1.282; TYW3 (gene name); tRNA-yW synthesizing enzyme-3. Cat No: EXWM-1889. | |
| tRNAPhe (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase | Requires Fe2+. The enzyme is not active with wybutosine. Group: Enzymes. Synonyms: TYW5; tRNA yW-synthesizing enzyme 5. Enzyme Commission Number: EC 1.14.11.42. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0661; tRNAPhe (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase; EC 1.14.11.42; TYW5; tRNA yW-synthesizing enzyme 5. Cat No: EXWM-0661. | |
| tRNAPhe [7-(3-amino-3-carboxypropyl)wyosine37-O]-methyltransferase | The enzyme is found only in eukaryotes, where it is involved in the biosynthesis of wybutosine, a hypermodified tricyclic base found at position 37 of certain tRNAs. The modification is important for translational reading-frame maintenance. In some species that produce hydroxywybutosine the enzyme uses 7-(2-hydroxy-3-amino-3-carboxypropyl)wyosine37 in tRNAPhe as substrate. The enzyme also has the activity of EC 2.3.1.231, tRNAPhe 7-[(3S)-4-methoxy-(3-amino-3-carboxypropyl)wyosine37-O]-carbonyltransferase. Group: Enzymes. Synonyms: TYW4 (ambiguous); tRNA-yW synthesizing enzyme-4 (ambiguous). Enzyme Commission Number: EC 2.1.1.290. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1897; tRNAPhe [7-(3-amino-3-carboxypropyl)wyosine37-O]-methyltransferase; EC 2.1.1.290; TYW4 (ambiguous); tRNA-yW synthesizing enzyme-4 (ambiguous). Cat No: EXWM-1897. | |
| tRNAPhe {7-[3-amino-3-(methoxycarbonyl)propyl]wyosine37-N}-methoxycarbonyltransferase | The enzyme is found only in eukaryotes, where it is involved in the biosynthesis of wybutosine, a hypermodified tricyclic base found at position 37 of certain tRNAs. The modification is important for translational reading-frame maintenance. In some species that produce hydroxywybutosine the enzyme uses 7-[2-hydroxy-3-amino-3-(methoxycarbonyl)propyl]wyosine37 in tRNAPhe as substrate. The enzyme also has the activity of EC 2.1.1.290, tRNAPhe [7-(3-amino-3-carboxypropyl)wyosine37-O]-methyltransferase. Group: Enzymes. Synonyms: TYW4 (ambiguous); tRNA-yW synthesizing enzyme-4 (ambiguous). Enzyme Commission Number: EC 2.3.1.231. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2179; tRNAPhe {7-[3-amino-3-(methoxycarbonyl)propyl]wyosine37-N}-methoxycarbonyltransferase; EC 2.3.1.231; TYW4 (ambiguous); tRNA-yW synthesizing enzyme-4 (ambiguous). Cat No: EXWM-2179. | |
| tRNA pseudouridine13 synthase | Pseudouridine synthase TruD from Escherichia coli specifically acts on uridine13 in tRNA. The Pus7 protein from Saccharomyces cerevisiae is a multisite-multisubstrate pseudouridine synthase that is able to modify uridine13 in several yeast tRNAs, uridine35 in the pre-tRNATyr, uridine35 in U2 small nuclear RNA, and uridine50 in 5S rRNA. Group: Enzymes. Synonyms: TruD; YgbO; tRNA PSI13 synthase; RNA:PSI-synthase Pus7p; Pus7p; RNA:pseudouridine-synthase Pus7p; Pus7 protein. Enzyme Commission Number: EC 5.4.99.27. CAS No. 430429-15-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5567; tRNA pseudouridine13 synthase; EC 5.4.99.27; 430429-15-5; TruD; YgbO; tRNA PSI13 synthase; RNA:PSI-synthase Pus7p; Pus7p; RNA:pseudouridine-synthase Pus7p; Pus7 protein. Cat No: EXWM-5567. | |
| tRNA pseudouridine31 synthase | The enzyme specifically acts on uridine31 in tRNA. Group: Enzymes. Synonyms: Pus6p. Enzyme Commission Number: EC 5.4.99.42. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5584; tRNA pseudouridine31 synthase; EC 5.4.99.42; Pus6p. Cat No: EXWM-5584. | |
| tRNA pseudouridine32 synthase | The dual-specificity enzyme from Escherichia coli also catalyses the formation of pseudouridine746 in 23S rRNA. cf. EC 5.4.99.29 (23S rRNA pseudouridine746 synthase). Group: Enzymes. Synonyms: RluA (ambiguous); pseudouridine synthase RluA (ambiguous); Pus9p; Rib2/Pus8p. Enzyme Commission Number: EC 5.4.99.28. CAS No. 430429-15-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5568; tRNA pseudouridine32 synthase; EC 5.4.99.28; 430429-15-5; RluA (ambiguous); pseudouridine synthase RluA (ambiguous); Pus9p; Rib2/Pus8p. Cat No: EXWM-5568. | |
| tRNA pseudouridine38/39 synthase | The enzyme from Saccharomyces cerevisiae is active only towards uridine38 and uridine39, and shows no activity with uridine40 (cf. EC 5.4.99.12, tRNA pseudouridine38-40 synthase). In vitro the enzyme from mouse is active on uridine39 and very slightly on uridine38 (human tRNALeu). Group: Enzymes. Synonyms: Deg1; Pus3p; pseudouridine synthase 3. Enzyme Commission Number: EC 5.4.99.45. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5587; tRNA pseudouridine38/39 synthase; EC 5.4.99.45; Deg1; Pus3p; pseudouridine synthase 3. Cat No: EXWM-5587. | |
| tRNA pseudouridine38-40 synthase | The uridylate residues at positions 38, 39 and 40 of nearly all tRNAs are isomerized to pseudouridine. TruA specifically modifies uridines at positions 38, 39, and/or 40 in the anticodon stem loop of tRNAs with highly divergent sequences and structures. Group: Enzymes. Synonyms: TruA; tRNA pseudouridine synthase I; PSUI; hisT (gene name). Enzyme Commission Number: EC 5.4.99.12. CAS No. 61506-89-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5551; tRNA pseudouridine38-40 synthase; EC 5.4.99.12; 61506-89-6; TruA; tRNA pseudouridine synthase I; PSUI; hisT (gene name). Cat No: EXWM-5551. | |
| tRNA (pseudouridine54-N1)-methyltransferase | While this archaeal enzyme is specific for the 54 position and does not methylate pseudouridine at position 55, the presence of pseudouridine at position 55 is necessary for the efficient methylation of pseudouridine at position 54. Group: Enzymes. Synonyms: TrmY; m1ψ methyltransferase. Enzyme Commission Number: EC 2.1.1.257. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1861; tRNA (pseudouridine54-N1)-methyltransferase; EC 2.1.1.257; TrmY; m1ψ methyltransferase. Cat No: EXWM-1861. | |
| tRNA pseudouridine55 synthase | Pseudouridine synthase TruB from Escherichia coli specifically modifies uridine55 in tRNA molecules. The bifunctional archaeal enzyme also catalyses the pseudouridylation of uridine54. It is not known whether the enzyme from Escherichia coli can also act on position 54 in vitro, since this position is occupied in Escherichia coli tRNAs by thymine. Group: Enzymes. Synonyms: TruB; aCbf5; Pus4; YNL292w (gene name); ψ55 tRNA pseudouridine synthase; tRNA:ψ55-synthase; tRNA pseudouridine 55 synthase; tRNA:pseudouridine-55 synthase; ψ55 synthase; tRNA ψ55 synthase; tRNA:ψ55 synthase; tRNA-uridine55 uracil mutase; Pus10; tRNA-uridine54/55 uracil mutase. Enzyme Commission Number: EC 5.4.99.25. CAS No. 430429-15-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5565; tRNA pseudouridine55 synthase; EC 5.4.99.25; 430429-15-5; TruB; aCbf5; Pus4; YNL292w (gene name); ψ55 tRNA pseudouridine synthase; tRNA:ψ55-synthase; tRNA pseudouridine 55 synthase; tRNA:pseudouridine-55 synthase; ψ55 synthase; tRNA ψ55 synthase; tRNA:ψ55 synthase; tRNA-uridine55 uracil mutase; Pus10; tRNA-uridine54/55 uracil mutase. Cat No: EXWM-5565. | |
| tRNA pseudouridine65 synthase | TruC specifically modifies uridines at positions 65 in tRNA. Group: Enzymes. Synonyms: TruC; YqcB. Enzyme Commission Number: EC 5.4.99.26. CAS No. 430429-15-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5566; tRNA pseudouridine65 synthase; EC 5.4.99.26; 430429-15-5; TruC; YqcB. Cat No: EXWM-5566. | |
| tRNA-queuosine β-mannosyltransferase | This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. Group: Enzymes. Enzyme Commission Number: EC 2.4.1.110. CAS No. 9055-6-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2337; tRNA-queuosine β-mannosyltransferase; EC 2.4.1.110; 9055-06-5. Cat No: EXWM-2337. | |
| tRNASer (uridine44-2'-O)-methyltransferase | The 2'-O-methylation of uridine44 contributes to stability of tRNASer(CGA). Group: Enzymes. Synonyms: TRM44. Enzyme Commission Number: EC 2.1.1.211. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1813; tRNASer (uridine44-2'-O)-methyltransferase; EC 2.1.1.211; TRM44. Cat No: EXWM-1813. | |
| tRNase Z | No cofactor requirements. An homologous enzyme to that found in Arabidopsis thaliana has been found in Methanococcus janaschii. Group: Enzymes. Synonyms: 3 tRNase; tRNA 3 endonuclease; RNase Z; 3' tRNase. Enzyme Commission Number: EC 3.1.26.11. CAS No. 98148-84-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3587; tRNase Z; EC 3.1.26.11; 98148-84-6; 3 tRNase; tRNA 3 endonuclease; RNase Z; 3' tRNase. Cat No: EXWM-3587. | |
| tRNA sulfurtransferase | A group of enzymes transferring sulfur to various nucleotides in a tRNA chain, producing residues such as 4-thiouridylate. With some enzymes mercaptopyruvate can act as sulfur donor. Group: Enzymes. Synonyms: transfer ribonucleate sulfurtransferase; RNA sulfurtransferase; ribonucleate sulfurtransferase; transfer RNA sulfurtransferase; transfer RNA thiolase. Enzyme Commission Number: EC 2.8.1.4. CAS No. 9055-57-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3362; tRNA sulfurtransferase; EC 2.8.1.4; 9055-57-6; transfer ribonucleate sulfurtransferase; RNA sulfurtransferase; ribonucleate sulfurtransferase; transfer RNA sulfurtransferase; transfer RNA thiolase. Cat No: EXWM-3362. | |
| tRNAThr (cytosine32-N3)-methyltransferase | The enzyme from Saccharomyces cerevisiae specifically methylates cytosine32 in tRNAThr and in tRNASer. Group: Enzymes. Synonyms: ABP140; Trm140p. Enzyme Commission Number: EC 2.1.1.268. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1873; tRNAThr (cytosine32-N3)-methyltransferase; EC 2.1.1.268; ABP140; Trm140p. Cat No: EXWM-1873. | |
| tRNA (uracil54-C5)-methyltransferase | Unlike this enzyme, EC 2.1.1.74 (methylenetetrahydrofolate-tRNA-(uracil54-C5)-methyltransferase (FADH2-oxidizing)), uses 5,10-methylenetetrahydrofolate and FADH2 to supply the atoms for methylation of U54. Group: Enzymes. Synonyms: transfer RNA uracil54 5-methyltransferase; transfer RNA uracil54 methylase; tRNA uracil54 5-methyltransferase; m5U54-methyltransferase; tRNA:m5U54-methyltransferase; RUMT; TrmA; 5-methyluridine54 tRNA methyltransferase; tRNA(uracil-54,C5)-methyltransferase; Trm2; tRNA(m5U54)methyltransferase. Enzyme Commission Number: EC 2.1.1.35. CAS No. 37257-02-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1939; tRNA (uracil54-C5)-methyltransferase; EC 2.1.1.35; 37257-02-6; transfer RNA uracil54 5-methyltransferase; transfer RNA uracil54 methylase; tRNA uracil54 5-methyltransferase; m5U54-methyltransferase; tRNA:m5U54-methyltransferase; RUMT; TrmA; 5-methyluridine54 tRNA methyltransferase; tRNA(uracil-54,C5)-methyltransferase; Trm2; tRNA(m5U54)methyltransferase. Cat No: EXWM-1939. | |
| tRNA-uridine 2-sulfurtransferase | The enzyme, found in bacteria, catalyses formation of the 2-thiouridine modification in the wobble position of tRNAGln, tRNALys and tRNAGlu. Group: Enzymes. Synonyms: mnmA (gene name). Enzyme Commission Number: EC 2.8.1.13. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3358; tRNA-uridine 2-sulfurtransferase; EC 2.8.1.13; mnmA (gene name). Cat No: EXWM-3358. | |
| tRNA-uridine aminocarboxypropyltransferase | The enzyme was studied in the bacterium Escherichia coli. The modification is found in the variable loop of the tRNA. Group: Enzymes. Synonyms: S-adenosyl-L-methionine:tRNA-uridine 3-(3-amino-3-carboxypropyl)transferase. Enzyme Commission Number: EC 2.5.1.25. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2762; tRNA-uridine aminocarboxypropyltransferase; EC 2.5.1.25; S-adenosyl-L-methionine:tRNA-uridine 3-(3-amino-3-carboxypropyl)transferase. Cat No: EXWM-2762. | |
| TRO 19622 | TRO 19622. Group: Biochemicals. Grades: Purified. CAS No. 22033-87-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| TRO 19622 | Olesoxime (TRO19622) is an experimental neuroprotective drug. It is the lead compound of Trophos' cholesterol-oxime compound family of mitochondrial pore modulators. It is a molecule that has a cholesterol-like structure and displays neuroprotective properties. TRO19622 is as effective as a cocktail of three neurotrophic factors in keeping motor neurons alive in culture. Preclinical studies have demonstrated that the compound promotes the function and survival of neurons and other cell types under disease-relevant stress conditions through interactions with the mitochondrial permeability transition pore (mPTP). A 2009-2011 phase 3 clinical trial of olesoxime in amyotrophic lateral sclerosis did not demonstrate a significant increase in survival versus placebo. The results of a 2011-2013 combined phase 2/3 trial of olesoxime in spinal muscular atrophy (SMA) indicated that the compound prevents deterioration of muscle function, suggesting that olesoxime might become the first drug approved to treat SMA. Synonyms: TRO-19622; TRO19622; TRO19622; RG6083; RG 6083; RG-6083; NSC 21311; NSC-21311; NSC21311; Olesoxime. Grades: >98%. CAS No. 22033-87-0. Molecular formula: C27H45NO. Mole weight: 399.65. |  |
| Trodusquemine | Trodusquemine, also called as MSI-1436 or Aminosterol-1436, with the potential to treat type 2 diabetes and obesity, it is a non-competitive cholestane inihbitor that specifically targets the enzyme protein tyrosine phosphatase 1B (PTB-1B) with 200-fold s. Synonyms: [ (3R, 6R) -6-[ (3S, 5R, 7R, 8R, 9S, 10S, 13R, 14S, 17R) -3-[3-[4- (3-aminopropylamino) butylamino]propylamino]-7-hydroxy-10, 13-dimethyl-2, 3, 4, 5, 6, 7, 8, 9, 11, 12, 14, 15, 16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylheptan-3-yl] hydrogen sulfate 3-N-1(sperm. CAS No. 186139-09-3. Molecular formula: C37H72N4O5S. Mole weight: 685.06. | |
| Troethylene Tetramine 112-24-3 | Troethylene Tetramine - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. |  North America & APAC |
| Trofinetide | Trofinetide (NNZ-2566), a synthetic analogue of the endogenous N-terminus tripeptide, Glycine-Proline-Glutamate (GPE), has been shown to be neuroprotective in animal models of brain injury. Uses: Scientific research. Group: Peptides. Alternative Names: NNZ-2566. CAS No. 853400-76-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16757. |  |
| Trofinetide | Trofinetide. Uses: For analytical and research use. Group: Impurity standards. CAS No. 853400-76-7. Molecular Formula: C13H21N3O6. Mole Weight: 315.33. Catalog: APB853400767. |  |
| Trofinetide | Trofinetide is a NMDA antagonist under the development of Neuren Pharmaceuticals. It is an analogue of the neuropeptide (1-3) IGF-1, which is a simple tripeptide with sequence Gly-Pro-Glu formed by enzymatic cleavage of the growth factor IGF-1 within the brain. Phase II clinical trials against Fragile X syndrome and Rett syndrome are on-going. Uses: Brain injuries; fragile x syndrome; rett syndrome. Synonyms: NNZ-2566; NNZ 2566; NNZ2566; Trofinetide; ((S)-1-glycyl-2-methylpyrrolidine-2-carbonyl)-L-glutamic acid. Grades: 98%. CAS No. 853400-76-7. Molecular formula: C13H21N3O6. Mole weight: 315.32. | |
| Trofinetide Impurity 1 | Trofinetide Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 42856-71-3. Molecular Formula: C6H11NO2. Mole Weight: 129.16. Catalog: APB42856713. | |
| Trofinetide Impurity 10 | Trofinetide Impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2603450-06-0. Molecular Formula: C15H25N3O6. Mole Weight: 343.38. Catalog: APB2603450060. | |
| Trofinetide Impurity 11 | Trofinetide Impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2603450-10-6. Molecular Formula: C15H25N3O6. Mole Weight: 343.38. Catalog: APB2603450106. | |
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