A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Trospium-d8 Chloride
Tropine derivative with anticholinergic activity. Antispasmodic; used in treatment of urinary incontinence. Group: Biochemicals. Alternative Names: (1α,3 β , 5α )-3-[(2-Hydroxy-2, 2-diphenylacetyl)oxy]-spiro[8-azoniabicyclo[3. 2. 1]octane-8, 1'-pyrrolidinium]-d8 Chloride; Azoniaspiro-d8; Keptan-d8; Relaspium-d8; Sanctura-d8; Spasmex-d8; Spasmo 3-d8. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Trospium Impurity B
Norglipin is an intermediate in the synthesis of Trospium Chloride. Synonyms: Norglipin; α-Hydroxy-α-phenylbenzeneacetic Acid (3-endo)-8-Azabicyclo[3.2.1]oct-3-yl Ester; N-Desmethyl Tropan-3α-yl-(2-hydroxy-2,2-diphenyl)acetate; 1αH,5αH-Nortropan-3α-ol Benzilate. CAS No. 16444-19-2. Molecular formula: C21H23NO3. Mole weight: 337.42.
Trospium Impurity C
Azoniaspironortropanol Chloride is an intermediate in the synthesis of Trospium Chloride. Synonyms: Azoniaspironortropanol Chloride; USP Trospium Chloride Related Compound C; (1α,3β,5α)-3-Hydroxyspiro[8-azoniabicyclo[3.2.1]octane-8,1'-pyrrolidinium] Chloride (1:1); 3-Hydroxyspiro[nortropane-8,1'-pyrrolidinium] Chloride; 3α-Hydroxynortropane-8-spiro-1'-pyrrolidinium Chloride. CAS No. 3464-71-9. Molecular formula: C11H20NO. Cl. Mole weight: 217.74.
Trospium impurity D
An impurity of Trospium. Trospium is a derivative of tropine with anticholinergic property, which is used in the treatment of urinary incontinence as an antispasmodic. Synonyms: Benzilide; 3,3,6,6-Tetraphenyl-1,4-dioxane-2,5-dione; NSC 403081; NSC 677243. CAS No. 467-32-3. Molecular formula: C28H20O4. Mole weight: 420.47.
Trotabresib
Trotabresib is a reversible inhibitor of epigenetic target bromodomain and extra-terminal (BET) protein with anti-tumor activity. Synonyms: CC 90010; CC-90010. Grades: >98%. CAS No. 1706738-98-8. Molecular formula: C21H21NO4S. Mole weight: 383.5.
Trotabresib
CC-90010 (compound 1) is a reversible and orally active BET inhibitor. CC-90010 is applied in the study for advanced solid tumors [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CC-90010. CAS No. 1706738-98-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-137573.
Trovafloxacin
Trovafloxacin is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive, Gram-negative and anaerobic organisms. Trovafloxacin blocks the DNA gyrase and topoisomerase IV activity. Trovafloxacin is also a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC50 of 4 μM for PANX1 inward current. Trovafloxacin does not inhibit connexin 43 gap junction or PANX2. Trovafloxacin leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1. Uses: Designed for use in research and industrial production. Additional or Alternative Names: TROVAFLOXACIN;1,8-Naphthyridine-3-carboxylic acid, 7-(1.alpha.,5.alpha.,6.alpha.)-6-amino-3-azabicyclo3.1.0hex-3-yl-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-;(1α,5α,6α)-7-(6-Amino-3-azabi-cyclo[3.1.0]hex-3-y1)-1-(2,4-difluomphenyl)-6-fluom-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid;CP-99219;Trovan:CP-99219-27;7-[(1R,5S)-6-amino-3-azabicyclo[3.1.0]hexan-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-keto-1,8-naphthyridine-3-carboxylic acid;7-[(1R,5S)-6-amino-3-azabicyclo[3.1.0]hexan-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid;7-[(1R,5S)-6-azanyl-3-azabicyclo[3.1.0]hexan-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid. Product Category: Inhibitors. CAS No. 147059-72-1. Molecular formula: C20H15F3N4O3. Mole weight: 416.35. Product ID: ACM
Trovafloxacin
Trovafloxacin is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive , Gram-negative and anaerobic organisms. Trovafloxacin blocks the DNA gyrase and topoisomerase IV activity. Trovafloxacin is also a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC 50 of 4 μM for PANX1 inward current. Trovafloxacin does not inhibit connexin 43 gap junction or PANX2. Trovafloxacin leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1 [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 147059-72-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0170.
Trovafloxacin mesylate
Trovafloxacin mesylate is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive, Gram-negative and anaerobic organisms. Trovafloxacin mesylate blocks the DNA gyrase and topoisomerase IV activity. Trovafloxacin mesylate is also a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC50 of 4 μM for PANX1 inward current. Trovafloxacin mesylate does not inhibit connexin 43 gap junction or PANX2. Trovafloxacin mesylate leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 7-[(1α,5α,6α)-6-Amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic Acid Methanesulfonate; CP 99219; CP 99219-27; Trovafloxacin Methanesulfonate; Trovafloxacin Monomethanesulfonate; Trovan. Product Category: Inhibitors. Appearance: White Solid. CAS No. 147059-75-4. Molecular formula: C20H15F3N4O3. Mole weight: 512.46. Purity: >99 %. IUPACName: 7-[(1S,5R)-6-amino-3-azabicyclo[3.1.0]hexan-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid; methanesulfonic acid. Canonical SMILES: CS(=O)(=O)O.C1C2C(C2N)CN1C3=C(C=C4C(=O)C(=CN(C4=N3)C5=C(C=C(C=C5)F)F)C(=O)O)F. Density: g/cm³. Product ID: ACM147059754. Alfa Chemistry ISO 9001:2015 Certified.
Trovafloxacin mesylate
Trovafloxacin mesylate is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive , Gram-negative and anaerobic organisms. Trovafloxacin mesylate blocks the DNA gyrase and topoisomerase IV activity. Trovafloxacin mesylate is also a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC 50 of 4 μM for PANX1 inward current. Trovafloxacin mesylate does not inhibit connexin 43 gap junction or PANX2. Trovafloxacin mesylate leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1 [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 147059-75-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-103399.
Trovafloxacin mesylate
Trovafloxacin mesylate is a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC50 of 4 μM for PANX1 inward current. It does not inhibit connexin 43 gap junction or PANX2. It leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1. It is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive, Gram-negative and anaerobic organisms. It is also an inhibitor of DNA topoisomerase and gyrase. Uses: Fluorinated quinolone antibacterial. trovafloxacin mesylate blocks the activity of dna gyrase and topoisomerase iv, enzymes essential in the repliction, transcription, and repair of bacterial dna. Synonyms: 7-[(1α,5α,6α)-6-Amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic Acid Methanesulfonate; CP 99219; CP 99219-27; Trovafloxacin Methanesulfonate; Trovafloxacin Monomethanesulfonate; Trovan; 1,8-Naphthyridine-3-carboxylic acid, 7-[(1R,5S)-6-amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-, methanesulfonate (1:1). Grades: ≥95%. CAS No. 147059-75-4. Molecular formula: C21H19F3N4O6S. Mole weight: 512.46.
Trovafloxacin Mesylate
Fluorinated quinolone antibacterial. Trovafloxacin mesylate blocks the activity of DNA gyrase and topoisomerase IV, enzymes essential in the repliction, transcription, and repair of bacterial DNA. Group: Biochemicals. Alternative Names: 7-[(1α, 5α, 6α)-6-Amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2, 4-difluorophenyl)-6-fluoro-1, 4-dihydro-4-oxo-1, 8-naphthyridine-3-carboxylic Acid Methanesulfonate; CP 99219; CP 99219-27; Trovafloxacin Methanesulfonate; Trovafloxacin Monomethanesulfonate; Trovan. Grades: Highly Purified. CAS No. 147059-75-4. Pack Sizes: 10mg. US Biological Life Sciences.
Trovirdine, a thiourea non-nucleoside reverse transcriptase inhibitor, was shown to inhibits HIV-1 RT when employing heteropolymeric primer/template (oligo-DNA/ribosomal RNA)and dGTP as substrate but inhibits has no development reported recently. IC50: HI. Synonyms: 1-(5-bromopyridin-2-yl)-3-(2-pyridin-2-ylethyl)thiourea LY 300046 LY-300046 LY300046.HCl N-(2-(2-pyridyl)ethyl)-N'-(2-(5-bromo)pyridyl)thiourea hydrochloride trovirdine. Grades: 99.43%. CAS No. 149488-17-5. Molecular formula: C13H13BrN4S. Mole weight: 337.24.
Trovirdine
Trovirdine inhibits HIV-1 RT with an IC50 of 7 nM when employing heteropolymeric primer/template (oligo-DNA/ribosomal RNA)and dGTP as substrate.IC50 value: 7 nMTarget: HIV-1Trovirdine is currently in phase I clinical trials for potential use in thetreatment of AIDS. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid. CAS No. 149488-17-5. Molecular formula: C13H13BrN4S. Mole weight: 337.24. Purity: 0.9862. Canonical SMILES: S=C(NCCC1=NC=CC=C1)NC2=NC=C(Br)C=C2. Product ID: ACM149488175. Alfa Chemistry ISO 9001:2015 Certified.
Troxacitabine
Troxacitabine. Group: Biochemicals. Alternative Names: 4-Amino-1-((2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl)pyrimidin-2(1H)-one. Grades: Highly Purified. CAS No. 145918-75-8. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C8H11N3O4. US Biological Life Sciences.
Worldwide
Troxerutin
Troxerutin, also known as vitamin P4, is a tri-hydroxyethylated derivative of natural bioflavonoid rutins which can inhibit the production of reactive oxygen species ( ROS ) and depress ER stress-mediated NOD activation. Uses: Scientific research. Group: Natural products. Alternative Names: Trihydroxyethylrutin. CAS No. 7085-55-4. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g; 25 g. Product ID: HY-N0139.
Troxerutin
Used in the treatment of venous disorders. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3,5-Dihydroxy-3',4',7-tris(2-hydroxyethoxy)flavone 3-rutinoside. Product Category: Material of cosmetics. Appearance: Powder. CAS No. 7085-55-4. Molecular formula: C22H34O3. Mole weight: 346.5. IUPACName: 2-[3,4-Bis(2-hydroxyethoxy)phenyl]-5-hydroxy-7-(2-hydroxyethoxy)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one. Canonical SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)OCCO)C5=CC(=C(C=C5)OCCO)OCCO)O)O)O)O)O)O. Density: 1.65±0.1 g/ml. Product ID: ACM7085554. Alfa Chemistry ISO 9001:2015 Certified.
Troxerutin
Troxerutin. Group: Biochemicals. Alternative Names: 3',4',7-?[O-(2-???)]??. Grades: Plant Grade. CAS No. 7085-55-4. Pack Sizes: 20mg. Molecular Formula: C33H42O19, Molecular Weight: 742.674999999999. US Biological Life Sciences.
Used in the treatment of venous disorders. Group: Biochemicals. Alternative Names: 2-[3,4-Bis(2-hydroxethoxy)phenyl]-3-[[6-O-(6-O-deoxy-a-L-mannopyranosyl)-B-D-glucopyranosyl]oxy]-5-hydroxy-7-(2-hydroxyethoxy)-4H-1-benzopyran-4-one, Posorutin, Ruven, Vastribil. Grades: Highly Purified. CAS No. 7085-55-4. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
Troxerutin Impurity 11
Troxerutin Impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 125092-04-8. Molecular formula: C29H34O17. Mole weight: 654.57. Catalog: APB125092048.
Troxerutin Impurity 3
Troxerutin Impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 13190-92-6. Molecular formula: C29H34O17. Mole weight: 654.57. Catalog: APB13190926.
Troxerutin Impurity 4
Troxerutin Impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 13190-91-5. Molecular formula: C31H38O18. Mole weight: 698.63. Catalog: APB13190915.
Troxerutin Impurity 7
Troxerutin Impurity 7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 13374-50-0. Molecular formula: C33H42O19. Mole weight: 742.68. Catalog: APB13374500.
Troxipide
Troxipide is a novel systemic non-antisecretory gastric cytoprotective agent with anti-ulcer, anti-inflammatory and mucus secreting properties irrespective of pH of stomach or duodenum. Synonyms: Benzamide, 3,4,5-trimethoxy-N-3-piperidinyl-; (±)-3,4,5-Trimethoxy-N-3-piperidinylbenzamide; Anytoral; Aplace fine gran; Troxin; Aplace; 3,4,5-Trimethoxy-N-(3-piperidyl)benzamide; BRN0493078. Grades: >98%. CAS No. 30751-05-4. Molecular formula: C15H22N2O4. Mole weight: 294.35.
Troxipide
Troxipide is an orally active defensive factor-enhancing therapeutic agent for gastritis and gastric ulcer (GU). Troxipide is a non-antisecretory gastro protective agent with antiulcer, anti-inflammatory and mucus-secreting properties [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 30751-05-4. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-B0758.
Troxipide
Troxipide. Group: Biochemicals. Grades: Highly Purified. CAS No. 99777-81-8. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C15H22N2O4. US Biological Life Sciences.
Worldwide
Trp(4)-Octreotide
Trp(4)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: L-Trp(4)-Octreotide; D-phenylalanyl-L-cystyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); H-D-Phe-Cys-Phe-L-Trp-Lys-Thr-Cys-Thr-ol (Disulfide bridge: Cys2-Cys7); (4R,7S,10S,13S,16S,19R)-13-((1H-indol-3-yl)methyl)-19-((R)-2-amino-3-phenylpropanamido)-10-(4-aminobutyl)-16-benzyl-N-((2R,3R)-1,3-dihydroxybutan-2-yl)-7-((R)-1-hydroxyethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carboxamide. Molecular formula: C49H66N10O10S2. Mole weight: 1019.25.
TrpA1 Antagonist, HC-030031 - CAS 349085-38-7
The TrpA1 Antagonist, HC-030031, also referenced under CAS 349085-38-7, controls the biological activity of TrpA1. This small molecule/inhibitor is primarily used for Neuroscience applications. Group: Fluorescence/luminescence spectroscopy.
TRPA1-IN-2
TRPA1-IN-2 (compound 1) is a potent and orally active TRPA1 inhibitor with an IC 50 value of 0.04 μM. TRPA1-IN-2 shows anti-inflammation activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2415206-22-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153711.
Trp-Arg
Tryptophanyl-arginine is a dipeptide composed of tryptophan and arginine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: L-Arginine, L-tryptophyl-; tryptophanyl-arginine; L-tryptophyl-L-arginine; (S)-2-((S)-2-Amino-3-(1H-indol-3-yl)propanamido)-5-guanidinopentanoic acid. Grades: ≥95% by HPLC. CAS No. 88831-09-8. Molecular formula: C17H24N6O3. Mole weight: 360.41.
A cell-permeable pyrazole derivative that acts as a selective blocker of the transient receptor potential cation channel TRPC3-medated ROCE (receptor-operated Ca2+ entry) and inhibits Carbachol-induced Ca2+ entry in TRPC3-expressing HEK293 cells (IC50 = 0.72uM; by Fura-2), while exhibiting much reduced potency against Stim1 and Orai1-coupled CRAC (Ca2+ release-activated Ca2+) channel-mediated SOCE (store-operated Ca2+ entry) in RBL-2H3 cells (IC50 = 13.08uM; by Fura-2). A great complement to Pyr2, Pyr 3, and Pyr6 in Ca2+ signaling studies. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
TRPC6-IN-3
TRPC6-IN-3 (compound 17) is a potent, orally active transient receptor potential C6 ion channel (TRPC6) inhibitor. TRPC6-IN-3 modulates not only intracellular calcium concentration, but also membrane potential by modulating the flux of cations including calcium and sodium ions. TRPC6-IN-3 can be used in research of respiratory system [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2311863-36-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148129.
TRPC6 inhibitor
TRPC6 inhibitor. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1333207-63-8. Molecular formula: C21H24Cl3N3O. Mole weight: 440.79. Catalog: APB1333207638.
A membrane permeable dihydroquinolinyloxo-isoindolinedione compound that acts as a potent and selective agonist of lysosomal mucolipin transient receptor potential (TRP) channel 1,2,3 (TRPML) in all mammalian cells. Does not appear to affect six other related TRP channels. Shown to rapidly activate whole-endolysosome TRPML-like current and induce lysosomal Ca2+ release (~10uM). Its activating action on whole-endolysosome is comparable to that of PI(3,5)P2 (1uM) with which it shows a synergistic effect. ML-SA1-induced Ca2+ responses are reportedly abolished by glycyl-L-phenylalanine 2-naphthylamide, induces osmotic lysis of lysosomes, and Bafilomycin A1, a V-ATPase inhibitor. Also reduces lactosylceramide and cholesterol accumulation and corrects trafficking defects in Niemann-Pick (NP) disease cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 332382-54-4. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
TRPML Agonist, ML-SA1 - CAS 332382-54-4
The TRPML Agonist, ML-SA1 controls the biological activity of TRPML. This small molecule/inhibitor is primarily used for Biochemicals applications. Group: Fluorescence/luminescence spectroscopy.
Trp-nle-arg-phe-nh2
Trp-nle-arg-phe-nh2. Uses: Designed for use in research and industrial production. Additional or Alternative Names: W-NLE-R-F-NH2;TRP-NLE-ARG-PHE-NH2;trp-nle-arg-phe amide acetate;TRP-NLE-ARG-PHE AMIDE;tryptophyl-norleucyl-arginyl-phenylalaninamide;TRP-NLE-ARG-PHE- (TRP-NLE-ARG-PHE-AMIDE ACETATE);tryptophan-norleucine-arginine-phenylalanine amide acetate. Product Category: Heterocyclic Organic Compound. CAS No. 83903-33-7. Molecular formula: C32H45N9O4. Mole weight: 619.76. Purity: 0.96. IUPACName: (2S)-2-[[(2S)-2-amino-3-(1H-indol-3-yl)propanoyl]amino]-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]hexanamide. Density: 1.34g/cm³. Product ID: ACM83903337. Alfa Chemistry ISO 9001:2015 Certified.
Trp-ser-lys-met-asp-gln-leu-ala-lys-glu-leu-thr-ala-glu. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CHROMOGRANIN A (324-337), HUMAN;CHROMOGRANIN A FRAGMENT 324-337 HUMAN;H-TRP-SER-LYS-MET-ASP-GLN-LEU-ALA-LYS-GLU-LEU-THR-ALA-GLU-OH;PEPTIDE WE-14;TRP-SER-LYS-MET-ASP-GLN-LEU-ALA-LYS-GLU-LEU-THR-ALA-GLU;chromogranina-derivedpeptide,we-14;chromogranin A fra. Product Category: Heterocyclic Organic Compound. CAS No. 115136-18-0. Molecular formula: C72H116N18O24S. Mole weight: 1649.86. Product ID: ACM115136180. Alfa Chemistry ISO 9001:2015 Certified.
The TRPV4 Antagonist II, HC-067047 controls the biological activity of TRPV4. Group: Fluorescence/luminescence spectroscopy.
TRPV4 Antagonist II, HC-067047 (2-Methyl-1- (3-morpholinopropyl) -5-phenyl-N- (3- (trifluoromethyl) phenyl) -1H-pyrrole-3-carboxamide, Transient Receptor Potential Vanilloid-4 Antagonist II, HC067047)
A pyrrolocarboxamide compound that potently antagonizes TRP (transient receptor potential) family cation channel TRPV4 activity (IC50 = 17, 48, and 133nM, respectively, against mouse, human, or rat TRPV4 in whole cell voltage-gated current measurement) in a reversible manner, displaying much reduced potency against human ERG and TRPM8 (IC50 = 368 and 780nM, respectively) and little or no activity toward hKv1.3, hTRPA1, hTRPC5, hTRPV1/2/3/6, mTRPM7, mTRPV2, or rKv1.2. HC-067047 is efficacious (10mg/kg via i.p.) in reducing micturition (urination) frequency and increasing voided urine volume of mice and rats suffering from CPA-induced cystitis in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
TRPV4 Antagonist I, RN-1734 (2, 4-Dichloro-N-isopropyl-N- (2-isopropylaminoethyl) benzenesulfonamide, Transient Receptor Potential Vanilloid-4 Antagonist I, RN1734)
A cell-permeable benzenesulfonamide compound that selectively antagonizes TRPV4 agonist 4a-PDD-stimulated Ca2+ influx (IC50 = 2.3, 3.2 and 5.9uM, respectively, in HEK293 expressing human, rat, or mouse TRPV4) without affecting the activity of three other human TRP (transient receptor potential) channels, including capsaicin- activated TRPV1, camphor-activated TRPV3, and methanol-activated TRPM8 (IC50 >30uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 946387-07-1. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
TRPV4 Antagonist I, RN-1734 - CAS 946387-07-1
The TRPV4 Antagonist I, RN-1734, also referenced under CAS 946387-07-1, controls the biological activity of TRPV4. This small molecule/inhibitor is primarily used for Biochemicals applications. Group: Fluorescence/luminescence spectroscopy.
TRPV antagonist 1
TRPV antagonist 1 is a transient receptor potential vanilloid (TRPV) antagonist (IC50= < 250 nM). Synonyms: 5H-Thiazolo[3,2-a]pyrimidin-5-one, 7-[(1E)-2-[2-(cyclopropylmethoxy)-3-methoxyphenyl]ethenyl]-6-[4-(trifluoromethoxy)phenyl]-. CAS No. 1192871-27-4. Molecular formula: C26H21F3N2O4S. Mole weight: 514.52.
Trt-Cysteamine HCl
S-Tritylcysteamine Hydrochloride has been shown to have an antileukemic activity. Synonyms: 2-tritylsulfanylethanamine, hydrochloride; S-tritylcysteamine HCl; S-trityl-D-cysteine; S-tritylcysteamine hydrochloride; S-trityl-2-mercaptoethylamine hydrochloride. Grades: ≥ 95%. CAS No. 15297-43-5. Molecular formula: C21H21NS·HCl. Mole weight: 355.92.
Trt-cysteamine hydrochloride
Trt-cysteamine hydrochloride. Group: Biochemicals. Alternative Names: 2-(Tritylthio)ethylamine hydrochloride. Grades: Highly Purified. CAS No. 15297-43-5. Pack Sizes: 1g, 2g, 5g. US Biological Life Sciences.
Worldwide
Trt-cysteamine hydrochloride 99+% (HPLC)
Trt-cysteamine hydrochloride 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g. US Biological Life Sciences.
Worldwide
Trtiyl-s-tityl-L-cyseteine
Trtiyl-s-tityl-L-cyseteine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: TRT-CYS(TRT)-OH; TRTIYL-S-TITYL-L-CYSETEINE. Product Category: Heterocyclic Organic Compound. CAS No. 27686-50-6. Molecular formula: C41H35NO2S. Mole weight: 605.8. Purity: 0.96. IUPACName: N,S-Ditrityl-L-Cystein. Product ID: ACM27686506. Alfa Chemistry ISO 9001:2015 Certified.
Tru9 I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 65°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme more than 95% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 500 U; 2500U. T↑TAA AAT↓T. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer W. Storage: -20°C. Form: Liquid. Source: An E.coli strain that carries the cloned Tru9 I gene from Thermus ruber 9. Pack: 10 mM Tris-HCl-(pH 7.5); 50 mM NaCl; 0,1 mM EDTA; 1 mM DTT; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1183RE.
True Blue
True Blue (NCI 240899) is a fluorescent dye, as neuronal retrograde tracer (excitation wavelength 395-425 nm, barrier filter 450 nm). True Blue can label neuron and has no effects on neuronal survival [1] [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: NCI 240899. CAS No. 71431-30-6. Pack Sizes: 1 mg. Product ID: HY-D1161.
True Blue Diaceturate Salt
True Blue Diaceturate Salt is a fluorescent neuronal tracer. It is also a salt form of 2, 2- (1, 2-Ethene diyl ) bis [5-benzofurancarboximidam ide ] (CAS 65426-90-6) which can be used in biological study for identification of small moecule inhibitors of anthrax lethal factor. Group: Biochemicals. Alternative Names: 2, 2- (1, 2-Ethene diyl ) bis-5-benzofurancarboximidam ide compd. with N-Acetylglycine. Grades: Purified. CAS No. 108321-12-6. Pack Sizes: 1mg, 5mg. Molecular Formula: C??H??N?O? 2(C?H?NO?), Molecular Weight: 578.58. US Biological Life Sciences.
Worldwide
TrueGel3D Crosslinker
CD cell-degradable crosslinker. Group: Fluorescence/luminescence spectroscopy.
TRULI
TRULI (Lats-IN-1) is a potent and ATP-competitive inhibitor of Lats1 and Lats2 kinases. TRULI promotes Yap-dependent proliferation in postmitotic mammalian tissues [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lats-IN-1. CAS No. 1424635-83-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138489.
Truncated (32-20)-Calcitonin
Truncated (32-20)-Calcitonin is an impurity of Calcitonin salmon, which is a calcium regulating hormone used to be an effective alternative for the treatment of postmenopausal osteoporosis. Synonyms: H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-NH2 (Disulfide bridge between Cys1 and Cys7); Calcitonin impurity-30; L-cysteinyl-L-seryl-L-asparagyl-L-leucyl-L-seryl-L-threonyl-L-cysteinyl-L-valyl-L-leucyl-glycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-alpha-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucinamide (1->7)-disulfide. Molecular formula: C88H152N26O27S2. Mole weight: 2070.46.
Truncated (32-27)-Calcitonin
Truncated (32-27)-Calcitonin is an impurity of Calcitonin salmon, which is a calcium regulating hormone used to be an effective alternative for the treatment of postmenopausal osteoporosis. Synonyms: H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-NH2 (Disulfide bond between Cys1 and Cys7); L-cysteinyl-L-seryl-L-asparagyl-L-leucyl-L-seryl-L-threonyl-L-cysteinyl-L-valyl-L-leucyl-glycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-alpha-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-asparaginamide (1->7)-disulfide. Molecular formula: C125H208N38O39S2. Mole weight: 2931.39.
Truncated (32-28)-Calcitonin
Truncated (32-28)-Calcitonin is an impurity of Calcitonin salmon, which is a calcium regulating hormone used to be an effective alternative for the treatment of postmenopausal osteoporosis. Synonyms: H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-NH2 (Disulfide bridge between Cys1 and Cys7); L-cysteinyl-L-seryl-L-asparagyl-L-leucyl-L-seryl-L-threonyl-L-cysteinyl-L-valyl-L-leucyl-glycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-alpha-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-asparagyl-L-threoninamide (1->7)-disulfide. Molecular formula: C129H215N39O41S2. Mole weight: 3032.49.
Truncated (32-29)-Calctonin
Truncated (32-29)-Calctonin is an impurity of Calcitonin salmon, which is a calcium regulating hormone used to be an effective alternative for the treatment of postmenopausal osteoporosis. Synonyms: H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-NH2 (Disulfide bridge between Cys1 and Cys7); Des-Ser-Gly-Thr-Pro-(32-29)-Calcitonin; Calcitonin impurity-31; L-cysteinyl-L-seryl-L-asparagyl-L-leucyl-L-seryl-L-threonyl-L-cysteinyl-L-valyl-L-leucyl-glycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-alpha-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-asparagyl-L-threonyl-glycinamide (1->7)-disulfide. Molecular formula: C131H218N40O42S2. Mole weight: 3089.54.
Truncated plakophilin-2 (581-590)
Truncated plakophilin-2 (581-590) is a truncated fragment of plakophilin-2 which is expressed in skin and cardiac muscle, where it functions to link cadherins to intermediate filaments in the cytoskeleton. This peptide can be used in Ovarian carcinoma related research.
Truxima is a bioanalogue of rituximab used for the treatment of all the indications of rituximab such as non-Hodgkin's lymphoma, chronic lymphocytic leukaemia (CLL), severe rheumatoid arthritis and granulomatosis with polyangiitis. Uses: All the indications of rituximab.
TRV-120027
TRV120027, a β-arrestin-1 -biased agonist of the angiotensin II receptor type 1 (AT1R) , engages -arrestins while blocking G-protein signaling [1]. TRV120027 induces acute catecholamine secretion through cation channel subfamily C3 (TRPC3) coupling, promotes the formation of a macromolecular complex composed of AT1R - β-arrestin-1 - TRPC3 - PLCγ at the plasma membrane. TRV120027 inhibits angiotensin II - mediated vasoconstriction and increases cardiomyocyte contractility. TRV120027 has the potential for the acute decompensated heart failure (ADHF) treatment [2]. Uses: Scientific research. Group: Peptides. CAS No. 1234510-46-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2141.