A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Tu-AMP 2 is an antimicrobial peptide isolated from Tulipa gesneriana L. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Lys-Ser-Cys-Cys-Arg-Asn-Thr-Thr-Ala-Arg-Asn-Cys-Tyr-Asn-Val-Cys-Arg-Ile-Pro-Gly.
Tubacin was used to study the role of HDAC6 in migration and invasion of bladder cancer cells. Tubacin (tubulin acetylation inducer) is a highly potent and selective, reversible, cell-permeable HDAC6 inhibitor with an IC50 of 4 nM. Uses: Histone deacetylase inhibitors. Synonyms: rel-N1-(4-((2R,4R,6S)-4-(((4,5-Diphenyloxazol-2-yl)thio)methyl)-6-(4-(hydroxymethyl)phenyl)-1,3-dioxan-2-yl)phenyl)-N8-hydroxyoctanediamide; Octanediamide, N1-(4-((2R,4R,6S)-4-(((4,5-diphenyl-2-oxazolyl)thio)methyl)-6-(4-(hydroxymethyl)phenyl)-1,3-dioxan-2-yl)phenyl)-N8-hydroxy-, rel-. Grades: ≥95%. CAS No. 537049-40-4. Molecular formula: C41H43N3O7S. Mole weight: 721.86.
Tubacin
Tubacin (Tubulin acetylation inducer) is a highly potent, selective, reversible, and cell-permeable inhibitor of histone deacetylase 6 (HDAC6, IC50=4nm). Displays 1000-fold more selectivity for HDAC6 over other HDACs. It inhibits a-tubulin deacetylation in mammalian cells. Unlike trichostatin A (TSA), which is a broad spectrum HDAC inhibitor, tubacin is specific for the tubulin deacetylase activity of HDAC6. Tubacin causes increased acetylation of a-tubulin, accumulation of polyubiquitinated proteins, and apoptosis. It does not affect global histone deacetylation, gene-expression profiling, or cell cycle progression mediated a-tubulin deacetylation in mammalian cells. Group: Biochemicals. Alternative Names: (N-[4-[(2R,4R,6S)-4-[[(4,5-Diphenyl- 2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3- dioxan-2-yl]phenyl]-N'-hydroxyoctanediamide). Grades: Highly Purified. CAS No. 537049-40-4. Pack Sizes: 500ug, 1mg, 2.5mg. Molecular Formula: C??H??N?O?S, Molecular Weight: 721.86. US Biological Life Sciences.
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Tubastatin A
Tubastatin A is selective at all isozymes except HDAC8 and maintains over 1000-fold selectivity against all isoforms excluding HDAC8, where it has approximately 57-fold selectivity. Grades: >98%. CAS No. 1252003-15-8. Molecular formula: C20H21N3O2. Mole weight: 335.4.
Tubastatin A HCl salt
Tubastatin A is a potent and selective HDAC6 inhibitor. Tubastatin A was substantially more selective than the known HDAC6 inhibitor Tubacin at all isozymes except HDAC8. Tubastatin A is a potent HDAC6 inhibitor with an IC50 value of 15 nM. Tubastatin A induces α-tubulin hyperacetylation at 2.5 μM in primary cortical neuron cultures. In a model of oxidative stress induced by glutathione depletion, tubastatin A displays dose-dependent neuronal protection of primary cortical neuron cultures at 5-10 μM. Grades: 0.98. CAS No. 1310693-92-5. Molecular formula: C20H22ClN3O2. Mole weight: 371.865.
Tubastatin A Hydrochloride. Group: Biochemicals. Alternative Names: N-Hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide Hydrochloride. Grades: Highly Purified. CAS No. 1310693-92-5. Pack Sizes: 10mg, 50mg, 100mg. Molecular Formula: C20H22ClN3O2, Molecular Weight: 371.86. US Biological Life Sciences.
Worldwide
Tubastatin A trifluoroacetate
Tubastatin A trifluoroacetate. Group: Biochemicals. Alternative Names: N-Hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide 2,2,2-trifluoroacetate. Grades: Highly Purified. CAS No. 1239262-52-2. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C22H22F3N3O4. US Biological Life Sciences.
Worldwide
Tubastatin A trifluoroacetate salt
Tubastatin A is a potent HDAC6 inhibitor with IC50 value of 15 nM. Tubastatin A induces α-tubulin hyperacetylation at 2.5 μM in primary cortical neuron cultures. In a model of oxidative stress induced by glutathione depletion, tubastatin A displays dose-dependent neuronal protection of primary cortical neuron cultures at 5-10 μM. Synonyms: N-Hydroxy-4-((2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)methyl)benzamide 2,2,2-trifluoroacetate. Grades: ≥95%. CAS No. 1239262-52-2. Molecular formula: C20H21N3O2·CF3COOH. Mole weight: 449.4.
Tubeimoside I
Tubeimoside I(Lobatoside-H) is an extract from Chinese herbal medicine Bolbostemma paniculatum (MAXIM. Uses: Scientific research. Group: Natural products. Alternative Names: Tubeimoside-1; Lobatoside-H. CAS No. 102040-03-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-N0890.
Tubeimoside I
Tubeimoside I. Group: Biochemicals. CAS No. 102040-03-9. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Tubeimoside II
Tubeimoside II. Group: Biochemicals. Grades: Plant Grade. CAS No. 115810-12-3. Pack Sizes: 20mg. Molecular Formula: C63H98O30, Molecular Weight: 1335.43. US Biological Life Sciences.
Worldwide
Tubeimoside II
Tubeimoside II. Group: Biochemicals. CAS No. 115810-12-3. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Tubeimoside II
Tubeimoside II is a natural analogue of oleanane type of triterpenoid saponin, showing anti-inflammatory, antitumor, and antitumor-promoting effects. Synonyms: Tubeimoside-B. Grades: >98%. CAS No. 115810-12-3. Molecular formula: C63H98O30. Mole weight: 1335.43.
Tubeimoside III
Tubeimoside III. Group: Biochemicals. Grades: Plant Grade. CAS No. 115810-13-4. Pack Sizes: 20mg. Molecular Formula: C64H100O31, Molecular Weight: 1365.46. US Biological Life Sciences.
Worldwide
Tubeimoside I (Lobatoside H)
Tubeimoside I (Lobatoside H). Group: Biochemicals. Alternative Names: 3-[[2-O-[4-O- (4-Carboxy-3-hydroxy-3-methyl-1-oxobutyl-) -a-L-arabinopyranosyl]-b-D-glucopyranosyl]oxy]-2, 23-dihydroxy-28- (O-b-D-xylopyranosyl- (1-3) -O-6-deoxy-a-L-mannopyranosyl- (1-2) -a-L-arabinopyranosyl) ester; Lobatoside H. Grades: Plant Grade. CAS No. 102040-03-9. Pack Sizes: 20mg. Molecular Formula: C63H98O29, Molecular Weight: 1319.43. US Biological Life Sciences.
Worldwide
Tuberactinomycin A
Tuberactinomycin A is produced by the strain of Streptoverticillium griseoverticillatus var. tuberacticus B-386. It is effective against mycobacteria, but less effective against gram-positive and gram-negative bacteria. CAS No. 33103-21-8. Molecular formula: C25H43N13O11. Mole weight: 701.69.
Tubercidin
Tubercidin. Group: Biochemicals. Alternative Names: 4-Amino-7-( β -D-ribofuranosyl) pyrrolo[2, 3-d]pyrimidine; 6-Amino-9-D-ribofuranosyl-7-desazapurine; 7-Deazaadenosine; Antibiotic XK 101-1; N7-Deazaadenosine; NSC 5640Sparsamycin A; Sparsomycin A; Tubercidine; U 10071. Grades: Highly Purified. CAS No. 69-33-0. Pack Sizes: 10mg. Molecular Formula: C11H14N4O3, Molecular Weight: 250.25. US Biological Life Sciences.
Worldwide
Tubercidin
Tubercidin (7-Deazaadenosine) is an antibiotic obtained from Streptomyces tubercidicus. Tubercidin inhibits the growth of Streptococcus faecalis (8043) with an IC50 of 0.02 μM. Tubercidin inhibits polymerases by incorporating DNA or RNA, thereby inhibiting DNA replication, RNA and protein synthesis. Tubercidin is a weak inhibitor of adenosine phosphorylase, and interferes with the phosphorylation of adenosine and AMP. Tubercidin has antiviral activity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: TUBERCIDIN;TUBERCIDINE;3-d)pyrimidin-4-amine,7-beta-d-ribofuranosyl-7h-pyrrolo(;3-d)pyrimidine,4-amino-7-beta-d-ribofuranosyl-7h-pyrrolo(;4-amino-7-(beta-d-ribofuranosyl)-pyrrolo(2,3-d)pyrimidine;4-amino-7-beta-d-ribofuranosyl-7h-pyrrolo(2,3-d)pyrimidine;7-beta-d-ribofuranosyl-7h-pyrrolo(2,3-d)pyrimidine-4-amine;7-deaza-adenosin. Product Category: Inhibitors. Appearance: Solid. CAS No. 69-33-0. Molecular formula: C11H14N4O4. Mole weight: 266.25. Purity: ≥98.0%. Canonical SMILES: O[C@H]1[C@@H](O)[C@H](N2C=CC3=C2N=CN=C3N)O[C@@H]1CO. Product ID: ACM69330. Alfa Chemistry ISO 9001:2015 Certified. Categories: Tube riding.
tuberculosinol synthase
Only found in species of Mycobacterium that cause tuberculosis. In addition, it also gives isotuberculosinol in 1:1 mixture, cf. EC 3.1.7.9, isotuberculosinol synthase. Group: Enzymes. Synonyms: Rv3378c. Enzyme Commission Number: EC 3.1.7.8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3768; tuberculosinol synthase; EC 3.1.7.8; Rv3378c. Cat No: EXWM-3768.
Tuberculosis inhibitor 12
Tuberculosis inhibitor 12 (compound 12) is an oxadiazole derivative and an inhibitor of Mycobacterium tuberculosis. The inhibition rates of Tuberculosis inhibitor 12 (20 μM) on 7H9-Tw-OADC and 7H9-Tw-OADC reached 82% and 78% respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 793729-44-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-49071.
Tuberculostearic Acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 10-methyloctadecanoic acid. Appearance: Colorless liquid. CAS No. 542-47-2. Molecular formula: C19H38O2. Mole weight: 298.5. Purity: 95% ethanol. Product ID: ACM542472. Alfa Chemistry ISO 9001:2015 Certified.
Tuberin
Tuberin is produced by the strain of Str.amakusaensis 10-101 and it is resistant to mycobacteria. Synonyms: N-Formyl-T-P-methoxystyrilamine; NSC 7382; N-trans-(p-Methoxystyryl)formamide. CAS No. 53643-53-1. Molecular formula: C10H11NO2. Mole weight: 177.20.
Tuberoside d(solanum)
Tuberoside d(solanum). Uses: Designed for use in research and industrial production. Additional or Alternative Names: collettisideiii; dioscine; polyphyllin III. Product Category: Heterocyclic Organic Compound. CAS No. 60478-68-4. Molecular formula: C45H72O16. Mole weight: 869.0436. Purity: 0.96. IUPACName: Dioscin. Canonical SMILES: CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)OC7C(C(C(C(O7)CO)OC8C(C(C(C(O8)C)O)O)O)O)OC9C(C(C(C(O9)C)O)O)O)C)C)C)OC1. Density: 1.39g/cm³. Product ID: ACM60478684. Alfa Chemistry ISO 9001:2015 Certified.
Tuberostemonine
Tuberostemonine. Group: Biochemicals. Grades: Plant Grade. CAS No. 6879-1-2. Pack Sizes: 20mg. Molecular Formula: C22H33NO4, Molecular Weight: 375.5. US Biological Life Sciences.
Worldwide
Tuberostemonine Trifluoroacetate
Tuberostemonine Trifluoroacetate. Group: Biochemicals. Pack Sizes: 5mg. US Biological Life Sciences.
recombinant, expressed in E. coli, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy.
tubulin GTPase
An intrinsic activity of α-tubulin involved in tubulin folding, division plane formation in prokaryotic cells and others. Group: Enzymes. Enzyme Commission Number: EC 3.6.5.6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4717; tubulin GTPase; EC 3.6.5.6. Cat No: EXWM-4717.
Tubulin Inhibitor 6
Tubulin inhibitor 6 is a tubulin inhibitor and an effective inhibitor of a variety of cancer cell lines. Synonyms: IHAP1; 2-Chloro-10-(4-Methoxybenzoyl)-10H-Phenothiazine; (2-Chloro-10H-Phenothiazin-10-Yl)(4-Methoxyphenyl)Methanone; Oprea1_789892. Grades: 98%. CAS No. 105925-39-1. Molecular formula: C20H14ClNO2S. Mole weight: 367.8.
tubulin-tyrosine ligase
L-Tyrosine is linked via a peptide bond to the C-terminus of de-tyrosinated α-tubulin (des-Tyrω-α-tubulin). The enzyme is highly specific for α-tubulin and moderately specific for ATP and L-tyrosine. L-Phenylalanine and 3,4-dihydroxy-L-phenylalanine are transferred but with higher Km values. Group: Enzymes. Enzyme Commission Number: EC 6.3.2.25. CAS No. 60321-03-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5743; tubulin-tyrosine ligase; EC 6.3.2.25; 60321-03-1. Cat No: EXWM-5743.
tubulinyl-Tyr carboxypeptidase
Active at neutral pH, from brain. Group: Enzymes. Synonyms: carboxypeptidase-tubulin; soluble carboxypeptidase; tubulin-tyrosine carboxypeptidase; tubulin carboxypeptidase; tubulinyltyrosine carboxypeptidase; tyrosinotubulin carboxypeptidase; tyrosyltubulin carboxypeptidase; TTCPase; brain I carboxypeptidase. Enzyme Commission Number: EC 3.4.17.17. CAS No. 73050-23-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4069; tubulinyl-Tyr carboxypeptidase; EC 3.4.17.17; 73050-23-4; carboxypeptidase-tubulin; soluble carboxypeptidase; tubulin-tyrosine carboxypeptidase; tubulin carboxypeptidase; tubulinyltyrosine carboxypeptidase; tyrosinotubulin carboxypeptidase; tyrosyltubulin carboxypeptidase; TTCPase; brain I carboxypeptidase. Cat No: EXWM-4069.
Tubuloside A
Tubuloside A. Group: Biochemicals. Grades: Plant Grade. CAS No. 112516-05-9. Pack Sizes: 20mg. Molecular Formula: C37H48O21, Molecular Weight: 828.76. US Biological Life Sciences.
Worldwide
Tubuloside A
Tubuloside A. Group: Biochemicals. CAS No. 112516-05-9. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Tubuloside A
Tubuloside A is a phenylethanoid glycoside with antioxidative effect and hepatoprotective activity. Synonyms: Tubuloside A; 112516-05-9; [(2R,3R,4S,5R,6R)-5-acetyloxy-6-[2-(3,4-dihydroxyphenyl)ethoxy]-2-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate; SCHEMBL4044477; MFCD28251989; AKOS037514890; (2R,3R,4S,5R,6R)-5-(acetyloxy)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-2-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)-4-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}oxan-3-yl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate. Grades: >98%. CAS No. 112516-05-9. Molecular formula: C37H48O21. Mole weight: 828.76.
Tubuloside B
Tubuloside B, one of the phenylethanoids isolated from the stems of Cistanche salsa, inhibits TNFα-induced apoptosis. Tubuloside B possesses antioxidative effects. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid. CAS No. 112516-04-8. Molecular formula: C31H38O16. Mole weight: 666.62. Purity: 0.98. Canonical SMILES: CC(O[C@@H]([C@@H](O1)OCCC(C=C2)=CC(O)=C2O)[C@H]([C@@H]([C@H]1COC(/C=C/C(C=C3)=CC(O)=C3O)=O)O)O[C@H](O[C@H]4C)[C@@H]([C@@H]([C@H]4O)O)O)=O. Product ID: ACM112516048. Alfa Chemistry ISO 9001:2015 Certified.
Tubulysin
The Tubulysin family of secondary metabolites was originally isolated from the myxobacteria Archangium geophyra and Angiococcus disciformis. These compounds are potent microtubule destabilizers and anti-microtubule toxins ( anti-microtubule toxins ), with effective IC 50 concentrations against multidrug-resistant cancer cell lines. In the picomole range. Tubulysins are ideal candidates for incorporation into small active molecule conjugate (SMDC) delivery systems and are commonly used in ADC synthesis as ADC cytotoxins ( ADC Cytotoxin ) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1943604-24-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-128914.
Tubulysin B
Tubulysin B is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates. It also has anti-fungal properties. Synonyms: (2S,4R)-2-Methyl-4-[2-[(1R,3R)-1-acetoxy-3-[[N-[[(2R)-1-methyl-2beta-piperidinyl]carbonyl]-L-isoleucyl](butanoyloxymethyl)amino]-4-methylpentyl]thiazole-4-ylcarbonylamino]-5-(4-hydroxyphenyl)pentanoic acid. Grades: ≥95%. CAS No. 205304-87-6. Molecular formula: C42H63N5O10S. Mole weight: 830.04.
Tubulysin C
Tubulysin C is a highly cytotoxic peptide isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis. Tubulysin C is a cytotoxic activity tubulysin which inhibits tubulin polymerization and leads to cell cycle arrest and apoptosis. Synonyms: Tubulysin C; 205304-88-7; 072P54KU0L; UNII-072P54KU0L; (2S,4R)-4-[[2-[(1R,3R)-1-acetyloxy-4-methyl-3-[[(2S,3S)-3-methyl-2-[[(2R)-1-methylpiperidine-2-carbonyl]amino]pentanoyl]-(propanoyloxymethyl)amino]pentyl]-1,3-thiazole-4-carbonyl]amino]-5-(4-hydroxyphenyl)-2-methylpentanoic acid; Benzenepentanoic acid, gamma-(((2-((1R,3R)-1-(acetyloxy)-4-methyl-3-(((2S,3S)-3-methyl-2-((((2R)-1-methyl-2-piperidinyl)carbonyl)amino)-1-oxopentyl)((1-oxopropoxy)methyl)amino)pentyl)-4-thiazolyl)carbonyl)amino)-4-hydroxy-alpha-methyl-, (alphaS. ga; SCHEMBL24218753; EX-A5466C; HY-N2347; AKOS040740942; CS-0021784; BENZENEPENTANOIC ACID. GAMMA.-(((2-((1R,3R)-1-(ACETYLOXY)-4-METHYL-3-(((2S,3S)-3-METHYL-2-((((2R)-1-METHYL-2-PIPERIDINYL)CARBONYL)AMINO)-1-OXOPENTYL)((1-OXOPROPOXY)METHYL)AMINO)PENTYL)-4-THIAZOLYL)CARBONYL)AMINO)-4-HYDROXY-.ALPHA.-METHYL-, (.ALPHA.S. GAMMA.R)-. Grades: 98%. CAS No. 205304-88-7. Molecular formula: C41H61N5O10S. Mole weight: 816.02.
Tubulysin D
Tubulysin D is a tetrapeptide isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis. It displays potent antitumor activity and leads to cell cycle arrest and apoptosis by inhibiting tubulin polymerization with an IC50 of 1.7 μM. Tubulysin displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC50 values in the lower nanomolar range. Synonyms: (+)-Tubulysin D. Grades: ≥98%. CAS No. 309935-57-7. Molecular formula: C43H65N5O9S. Mole weight: 828.07.
Tucaresol
Tucaresol is an orally bioavailable immunopotentiatory drug that show to enhance T-helper-cell activity, with the induction of increased IL-2 and IFN-γ levels in mice and humans. Tucaresol has anti- HIV effect [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BWA589C. CAS No. 84290-27-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106755.
Tucatinib
Tucatinib (Irbinitinib) is a potent, orally active and selective HER2 inhibitor with an IC 50 of 8 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Irbinitinib; ARRY-380; ONT-380. CAS No. 937263-43-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16069.
Tucidinostat
Tucidinostat (Chidamide) is a potent and orally bioavailable HDAC enzymes class I ( HDAC1/2/3 ) and class IIb ( HDAC10 ) inhibitor, with IC 50 s of 95, 160, 67 and 78 nM, less active on HDAC8 and HDAC11 ( IC 50 s, 733 nM, 432 nM, respectively), and shows no effect on HDAC4/5/6/7/9 [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Chidamide; HBI-8000; CS 055. CAS No. 1616493-44-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109015.
Tucidinostat is a novel inhibitor of HDAC1, 2, 3, and 10 with IC50 values of 95, 160, 67, 78 nM, respectively. It increases the acetylation levels of histone H3 and decreases histone deacetylase (HDAC) activity, inducing apoptosis of cancer cells. Synonyms: HBI-8000; CS-055; Chidamide; Epidaza. CAS No. 1616493-44-7. Molecular formula: C22H19FN4O2. Mole weight: 390.41.
Tuftsin
Tuftsin is a tetrapeptide. Tuftsin is a macrophage/microglial activator. Uses: Scientific research. Group: Peptides. CAS No. 9063-57-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P0240.
Tuftsin
Tuftsin is a tetrapeptide located in the Fd fragment of the gamma-globulin molecule. Tuftsin is a macrophage/microglial activator. Synonyms: L-Arginine, L-threonyl-L-lysyl-L-prolyl-; L-Arginine, N2-[1-(N2-L-threonyl-L-lysyl)-L-prolyl]-; L-Threonyl-L-lysyl-L-prolyl-L-arginine; Tafcine; Taftsin; Taphcin; H-Thr-Lys-Pro-Arg-OH. Grades: 95%. CAS No. 9063-57-4. Molecular formula: C21H40N8O6. Mole weight: 500.59.
Tuftsin 3TFA
Tuftsin is a tetrapeptide located in the Fd fragment of the gamma-globulin molecule. Tuftsin is a macrophage/microglial activator. Synonyms: L-Arginine, N2-[1-(N2-L-threonyl-L-lysyl)-L-prolyl]-, tris(trifluoroacetate) (salt); Acetic acid, trifluoro-, compd. with N2-[1-(N2-L-threonyl-L-lysyl)-L-prolyl]-L-arginine (3:1); H-Thr-Lys-Pro-Arg-OH.3TFA; L-threonyl-L-lysyl-L-prolyl-L-arginine trifluoroacetic acid; TKPR.3TFA. Grades: ≥95%. CAS No. 81019-03-6. Molecular formula: C21H40N8O6.3C2HF3O2. Mole weight: 842.66.
TUG424 is a a potent and selective free fatty acid receptor 1 agonist. It is expected to be useful in the exploration of FFA1 and may also be valuable as a lead structure for new potential antidiabetic therapeutics. Uses: Tug424 may be valuable as a lead structure for new potential antidiabetic therapeutics. Synonyms: TUG-424; TUG424; TUG 424; 4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid;CAY10587;3-(4-(o-Tolylethynyl)phenyl)propanoic acid; TUG-424; 3-[4-[ (2-Methylphenyl) ethynyl]phenyl]propanoic acid. Grades: >99 %. CAS No. 1082058-99-8. Molecular formula: C18H16O2. Mole weight: 264.32.
This active molecular is a free fatty acid (FFA) 1 receptor agonist. TUG-469 is more than two hundred fold selective for FFA1 over FFA4. TUG-469 can potential use for the treatment of type 2 diabetes mellitus as a selectively FFA1 inhibitor. Activation of the FFA1 leads to an enhancement of glucose-stimulated insulin secretion from pancreatic β-cells. Uses: Type 2 diabetes mellitus. Synonyms: TUG469; TUG 469; TUG-469; 4-[[(2'-Methyl[1,1'-biphenyl]-3-yl)methyl]amino]benzenepropanoic Acid; 3-(4-(((2'-Methyl-[1,1'-biphenyl]-3-yl)methyl)amino)phenyl)propanoic Acid. Grades: 98%. CAS No. 1236109-67-3. Molecular formula: C23H23NO2. Mole weight: 345.44.
TUG-770
TUG-770 displayed excellent physicochemical and in vitro ADME properties, with good aqueous solubility, good chemical stability, low lipophilicity, and decreased plasma protein binding (PPB). TUG-770 furthermore showed excellent stability toward human liver microsomes (HLM), no inhibition of selected CYP-enzymes implicated in drug-drug interactions, no P-glycoprotein (P-gp) inhibition, and good permeability in the Caco-2 cell assay. Examination of TUG-770 in an acute intraperitoneal glucose tolerance test (IPGTT) in normal mice revealed a good dose dependent response with maximal reduction in glucose level reached at 50 mg/kg. The effect of TUG-770 was fully sustained after 29 days of daily oral treatment. Additional evaluation of TUG-770 in rats confirmed a significant glucose lowering effect for the high doses already after 10 min and for all doses after 30 min. Synonyms: TUG-770; TUG 770; TUG770. Grades: >98%. CAS No. 1402601-82-4. Molecular formula: C19H14FNO2. Mole weight: 307.32.
TUG 891
TUG-891 is a selective free fatty acid receptor 4 (FFA4/GPR120)agonist. pEC50 values are 7.36 for human and 7.77 for mouse GPR120. TUG-891 also activates GPR40 (FFAR1) with a pEC50 value of 4.19 but shows no activity at GPR41 (FFAR3) or GPR43 (FFAR2). Synonyms: GPU-028; GPU-028; GPU-028; 2,2-d2-TUG-891; 2,2d2TUG891; 2,2 d2 TUG 891; 4-[(4-fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]-benzenepropanoic acid. Grades: 98%. CAS No. 1374516-07-0. Molecular formula: C23H19D2FO3. Mole weight: 364.41.
TUG 891
TUG 891. Group: Biochemicals. Alternative Names: 4- [ (4-Fluoro-4'-methyl [1, 1'-biphenyl] -2-yl) methoxy] benzenepropanoic Acid. Grades: Highly Purified. CAS No. 1374516-07-0. Pack Sizes: 10mg. Molecular Formula: C23H21FO3, Molecular Weight: 364.41. US Biological Life Sciences.
Worldwide
TUG-891
TUG-891 is a potent and selective agonist for the long chain free fatty acid (LCFA) receptor 4 ( FFA4/GPR120 ) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1374516-07-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100881.
TUG-905 is a Free Fatty Acid Receptor 4 (FFA4/GPR120) Agonist. Synonyms: TUG-905; TUG 905; TUG905. 3-(2-fluoro-4-(((2'-methyl-4'-(3-(methylsulfonyl)propoxy)-[1,1'-biphenyl]-3-yl)methyl)amino)phenyl)propanoic acid. Grades: 98%. CAS No. 1390641-90-3. Molecular formula: C27H30FNO5S. Mole weight: 499.60.
Tulathromycin A
Triamilide antibiotic for treatment of bovine and porcine respiratory disease. Exists as an equilibrium mixture of two isomeric forms, Tulathromycin A (90%) and B (10%). Antibacterial. Group: Biochemicals. Alternative Names: (2R, 3S, 4R, 5R, 8R, 10R, 11R, 12S, 13S, 14R)-13-[[2, 6-Dideoxy-3-C-methyl-3-O-methyl-4-C-[(propylamino)methyl]-a-L-ribo-hexopyranosyl]oxy]-2-ethyl-3, 4, 10-trihydroxy-3, 5, 8, 10, 12, 14-hexamethyl-11-[[3, 4, 6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one; CP 472295; Draxxin. Grades: Highly Purified. CAS No. 217500-96-4. Pack Sizes: 100mg, 500mg, 1g. Molecular Formula: C41H79N3O12, Molecular Weight: 806.08. US Biological Life Sciences.
Worldwide
Tulathromycin A
Tulathromycin A, also known as Tulathromycin and CP-472295, is a macrolide antibiotic used to treat bovine respiratory disease (BRD) in cattle and swine respiratory disease in pigs. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Tulathromycin; Draxxin; Tulathromycin A; CP-472,295; CP-472295; CP 472295; CP472295. Product Category: Others. Appearance: Solid powder. CAS No. 217500-96-4. Molecular formula: C41H79N3O12. Mole weight: 806.09. Purity: >98%. IUPACName: (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyl-5-(propylaminomethyl)oxan-2-yl]oxy-3,5,8,10,12,14-hexamethyl-1-oxa-6-azacyclopentadecan-15-one. Canonical SMILES: O=C1[C@H](C)[C@@H](O[C@@H]2O[C@@H](C)[C@](CNCCC)(O)[C@](C)(OC)C2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@H](N(C)C)[C@H]3O)[C@](C)(O)C[C@@H](C)CN[C@H](C)[C@@H](O)[C@](C)(O)[C@@H](CC)O1. Density: 1.17. Product ID: ACM217500964. Alfa Chemistry ISO 9001:2015 Certified.
Tulathromycin A
?95% (HPLC). Group: Fluorescence/luminescence spectroscopypharma & vet compounds & metabolitespharma & vet compounds & metabolitescarbohydrateschiral molecules. Alternative Names: (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[[2,6-Dideoxy-3-C-methyl-3-O-methyl-4-C-[(propylamino)methyl]-?-L-ribo-hexopyranosyl]oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-?-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one, Tulathromycin, Draxxin, CP 472295, Tulathromycin A.
Tulathromycin A
Tulathromycin A (Tulathromycin), a macrolide antibiotic , inhibits protein synthesis (IC 50 =0.26 μM) by targeting bacterial ribosome. Tulathromycin A is used for the research of respiratory disease in cattle and swine. Immunomodulatory effects [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tulathromycin; CP 472295. CAS No. 217500-96-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15662.
Tulathromycin A Impurity 1
An impurity of Tulathromycin A. Tulathromycin A is a macrolide antibiotic used to treat bovine and swine respiratory disease (BRD). Molecular formula: C29H56N2O9. Mole weight: 576.78.
Tulathromycin B
Tulathromycin B is an isomer of Tulathromycin A used for the treatment of bacterial infections. Synonyms: TULATHROMYCIN B; Tulathromycin; (2R,3R,6R,8R,9R,10S,11S,12R)-11-[[2,6-Dideoxy-3-C-methyl-3-O-methyl-4-C-[(propylamino)methyl]-a-L-ribo-hexopyranosyl]oxy]-2-[(1R,2R)-1,2-dihydroxy-1-methylbutyl]-8-hydroxy-3,6,8,10,12-pentamethyl-9-[[3,4,6-trideoxy-3-(dimeth. Grades: 98%. CAS No. 280755-12-6. Molecular formula: C41H79N3O12. Mole weight: 806.084.