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| Product | Description | |
|---|---|---|
| TFAP | TFAP is a selective cyclooxygenase-1 (COX-1) inhibitor, with an IC 50 of 0.8 μM. Uses: Scientific research. Group: Natural products. Alternative Names: N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide. CAS No. 1011244-68-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112731. |  |
| Tfa-Phe-OH | Tfa-Phe-OH. Synonyms: (S)-N-(trifluoroacetyl)phenylalanine; N-Trifluoroacetyl-L-phenylalanine; Tfa Phe OH. CAS No. 350-09-4. Molecular formula: C11H10F3NO3. Mole weight: 261.2. |  |
| TFB | TFB, a hole transporting material and an electron-blocking layer, has high hole mobility, low electron affinity, and high ionic potential. Its electron blocking nature results in effective confinement of injected charge carriers in the perovskite layers. Uses: Tfb can be used in the formation of multilayer quantum dot-based light-emitting diodes (leds). it can also be used in the fabrication of highly responsive gas sensors for breath analysis. Group: Perovskite materials organic light-emitting diode (oled) materials. Alternative Names: Poly[(9,9-dioctylfluorenyl-2,7-diyl)-co-(4,4'-(N-(4-sec-butylphenyl)diphenylamine)]. CAS No. 220797-16-0. Pack Sizes: 250 mg/1 g. Product ID: N-(4-butan-2-ylphenyl)-4-(9,9-dioctyl-7-phenylfluoren-2-yl)aniline. Molecular formula: 1241.43. Mole weight: (C51H61N)n. CCCCCCCCC1 (CCCCCCCC)C2=C (C=CC (C3=CC=C (N (C4=CC=C (C (CC)C)C=C4)C5=CC=C (C)C=C5)C=C3)=C2)C6=C1C=C (C)C=C6. 1S/C53H67N/c1-7-10-12-14-16-18-36-53 (37-19-17-15-13-11-8-2)51-38-41 (5)22-34-49 (51)50-35-27-45 (39-52 (50)53)44-25-32-48 (33-26-44)54 (46-28-20-40 (4)21-29-46)47-30-23-43 (24-31-47)42 (6)9-3/h20-35, 38-39, 42H, 7-19, 36-37H2, 1-6H3. LMXSDGRJIJNLIY-UHFFFAOYSA-N. |  |
| TFC 007 | TFC 007. Group: Biochemicals. Grades: Purified. CAS No. 927878-49-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| TFCA | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| TFEB activator 1 | TFEB activator 1 is an orally effective, mTOR-independent activator of TFEB. TFEB activator 1 significantly promotes the nuclear translocation of Flag-TFEB with an EC50 of 2167 nM. TFEB activator 1 enhances autophagy without inhibiting the mTOR pathway and has the potential for neurodegenerative diseases treatment[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 39777-61-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135825. | |
| TFF1 human | recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| TFF-2 human | recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| TFF3 human | recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| TFFH | TFFH. Group: Biochemicals. Alternative Names: Fluoro-N, N, N', N'-tetra methyl formamidinium hexafluorophosphate. Grades: Highly Purified. CAS No. 164298-23-1. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C5H12FN2·F6P. US Biological Life Sciences. | Worldwide |
| TFFYGGSRGKRNNFKTEEYC | TFFYGGSRGKRNNFKTEEYC is a peptide, which can be used for glioma targeted therapy. Grade: 98%. CAS No. 906480-09-9. Molecular formula: C107H154N30O32S. Mole weight: 2404.6. | |
| TFIIA-p12 human | recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| TFIIA (p12), ? subunit, GST tagged human | recombinant, expressed in E. coli, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| TFIIA-p55 human | recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| TFIIA, p55 subunit, GST tagged human | recombinant, expressed in E. coli, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| TFIIA, reconstituted human | recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| TFIIB, GST tagged human | recombinant, expressed in E. coli, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| TFIID, native complex human | ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| TFIIE ?, p34 human | recombinant, expressed in E. coli, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| TFIIE ?, p56 human | recombinant, expressed in E. coli, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| TFIIE, ? (p56), ? subunit, GST tagged human | recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| TFIIE, ?+? subunits human | recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| TFIIF (RAP30+Rap74) human | recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| TFIIF, Rap30 subunit, GST tagged human | recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| TFIIF (RAP30 subunit) human | recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| TFIIF (RAP74 subunit) human | recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| TFIIH, native complex human | ?75% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| TFIIH, p62 subunit human | recombinant, expressed in E. coli, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| TFLLR-NH2 | TFLLR-NH2. Group: Biochemicals. Grades: Purified. CAS No. 197794-83-5. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| TFLLR-NH2 | TFLLR-NH2, derived from the protease-activated receptor-1 (PAR1), is a selective PAR1 agonist with an EC50 of 1.9 μM. Synonyms: TFLLR amide; (Thr1)-TRAP-5 amide; (Thr1)-PAR-1 (1-5) amide (human); PAR-1-activating peptide; PAR-1-AP; L-threonyl-L-phenylalanyl-L-leucyl-L-leucyl-L-argininamide. Grade: 98%. CAS No. 197794-83-5. Molecular formula: C31H53N9O6. Mole weight: 647.81. | |
| TFLLR-NH2 2TFA | TFLLR-NH2 2TFA, derived from the protease-activated receptor-1 (PAR1), is a selective PAR1 agonist with an EC50 of 1.9 μM. Synonyms: H-Thr-Phe-Leu-Leu-Arg-NH2.2TFA; TFLLR-NH2.2TFA; L-threonyl-L-phenylalanyl-L-leucyl-L-leucyl-L-argininamide trifluoroacetic acid; PAR-1-AP trifluoroacetate; Protease-activated receptor-1-activating peptide trifluoroacetate. Grade: ≥95%. Molecular formula: C31H53N9O6.2C2HF3O2. Mole weight: 875.87. | |
| TFLLR-NH2(TFA) | TFLLR-NH2, derived from the protease-activated receptor-1 (PAR1), is a selective PAR1 agonist with an EC50 of 1.9 μM. Synonyms: TFLLR-NH2 trifluoroacetate salt; L-threonyl-L-phenylalanyl-L-leucyl-L-leucyl-L-argininamide trifluoroacetic acid. Grade: 99%. CAS No. 1313730-19-6. Molecular formula: C33H54F3N9O8. Mole weight: 761.83. | |
| TFLLR-NH2 trifluoroacetate salt | >98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| TFM-4AS-1 | TFM-4AS-1. Group: Biochemicals. Grades: Purified. CAS No. 188589-61-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TFM-4AS-1 | TFM-4AS-1 is a selective androgen receptor modulator (SARM) , and a potent androgen receptor (AR) ligand with an IC 50 of 38 nM. TFM-4AS-1 is a gene-selective agonist [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 188589-61-9. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-103246. | |
| TFMB-(R)-2-HG | TFMB-(R)-2-HG, a cell membrane-permeable version of (R)-2-HG, is a carcinogenic factor in Acute myeloid leukemia (AML). TFMB-(R)-2-HG impairs SCF ER-Hoxb8 cells differentiation in response to estrogen withdrawal [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1445700-01-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129079. | |
| TFMB-(S)-2-HG | TFMB-(S)-2-HG is a potent TET2 inhibitor. TFMB-(S)-2-HG also inhibits the EglN prolyl hydroxylases. TFMB-(S)-2-HG downregulates Wnt3a, ?-catenin (intranuclear) protein expression. TFMB-(S)-2-HG inhibits osteogenic differentiation of cells. TFMB-(S)-2-HG has the potential for the research of acute myeloid leukemia (AML)[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1445703-64-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129079A. | |
| TFP-PEG12-biotinidase resistant biotin | TFP-PEG12-biotinidase resistant biotin. Synonyms: TFP-PEG12-biotinidase resistant biotin; GS-9358; TFP-dPEG(R)12-biotinidase resistant biotin. Molecular formula: C47H76F4N4O17S. Mole weight: 1077.2. | |
| TFP-PEG3-TFP | TFP-PEG3-TFP. Uses: Designed for use in research and industrial production. Product Category: Other PEG Linkers. CAS No. 1446282-34-3. Molecular formula: C22H18F8O7. Mole weight: 546.09. Purity: 95%+. Product ID: ACM1446282343. Alfa Chemistry ISO 9001:2015 Certified. |  |
| TFP-PEG4-biotinidase resistant biotin | TFP-PEG4-biotinidase resistant biotin. Synonyms: TFP-PEG4-biotinidase resistant biotin; GS-9357; TFP-dPEG(R)4-biotinidase resistant biotin. Molecular formula: C31H44F4N4O9S. Mole weight: 724.8. | |
| TfR-T12 | TfR-T12 is a BBB-penetrated transferrin receptor (TfR) binding peptide. CAS No. 344618-30-0. Molecular formula: C71H99N19O15S. Mole weight: 1490.73. | |
| TfR Targeting Peptide | The 12-mer peptide sequence is a transferrin receptor (TfR) targeting peptide. It binds to TfR and is internalized via endocytosis into TfR-expressing cells. TfR targeting peptide is a potential carrier for transportation of small molecules across the blood-brain barrier to the brain, or into malignant tissues. Synonyms: H-Thr-His-Arg-Pro-Pro-Met-Trp-Ser-Pro-Val-Trp-Pro-OH; L-threonyl-L-histidyl-L-arginyl-L-prolyl-L-prolyl-L-methionyl-L-tryptophyl-L-seryl-L-prolyl-L-valyl-L-tryptophyl-L-proline; TfR-T12. Grade: ≥95%. Molecular formula: C71H99N19O15S. Mole weight: 1490.75. | |
| TG003 | TG003 is a potent inhibitor of Clk1/Sty; inhibits Clk1 and Clk4 with IC50 values of 20 and 15 nM, respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 719277-26-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15338. | |
| TG003 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| TG 003 | TG 003. Group: Biochemicals. Grades: Purified. CAS No. 719277-26-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TG 100713 | TG 100713. Group: Biochemicals. Grades: Purified. CAS No. 925705-73-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TG 100801 | TG 100801 is a proagent that generates TG 100572 by de-esterification in development to treat age-related macular degeneration. TG 100572 is a multi-targeted kinase inhibitor which inhibits receptor tyrosine kinases and Src kinases ; has IC 50 s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 nM for VEGFR1 , VEGFR2 , FGFR1 , FGFR2 , PDGFRβ , Fgr , Fyn , Hck , Lck , Lyn , Src , Yes , respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 867331-82-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10186. | |
| TG101209 | TG101209 is a selective JAK2 inhibitor with IC 50 of 6 nM, less potent to Flt3 and RET with IC 50 of 25 nM and 17 nM, appr 30-fold selective for JAK2 than JAK3, and sensitive to JAK2V617F and MPLW515L/K mutations. Uses: Scientific research. Group: Signaling pathways. CAS No. 936091-14-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10410. | |
| TG101209 | TG101209. Group: Biochemicals. Alternative Names: N- (1, 1-Dimethylethyl) -3- [ [5-methyl-2- [ [4- (4-methyl-1-piperazinyl) phenyl] amino] -4-pyrimidinyl] amino] benzenesulfonamide. Grades: Highly Purified. CAS No. 936091-14-4. Pack Sizes: 2.5mg. Molecular Formula: C26H35N7O2S, Molecular Weight: 509.67. US Biological Life Sciences. | Worldwide |
| TG101348 (SAR302503) | TG101348 is a potent, and selective inhibitor of JAK2 (IC50 = 3 nM). It has a 35- and 334-fold selectivity over JAK3 and JAK1, respectively. Group: Biochemicals. Alternative Names: N-tert-butyl-3- (5-methyl-2- (4- (2- (pyrrolidin-1-yl) ethoxy) phenylamino) pyrimidin-4-ylamino) benzenesulfonamide. Grades: Highly Purified. CAS No. 936091-26-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| TG 4-155 | TG 4-155. Group: Biochemicals. Grades: Purified. CAS No. 1164462-05-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TG4-155 | TG4-155 is a potent, brain-permeant and selective EP2 receptor antagonist with a K i of 9.9 nM [1] [2]. TG4-155 shows low nanomolar antagonist activity against only EP2 and DP1 [1]. TG4-155 has an EP2 Schild K B of 2.4 nM and displays 550-4750-fold selectivity for EP2 over EP1, EP3, EP4 and IP, but only 14-fold selectivity against the DP1 receptor [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1164462-05-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-18971. | |
| TG4-155 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| TG53 | TG53 is a novel inhibitor of tissue transglutaminase (TG2) and fibronectin (FN) protein-protein interaction. Group: Biochemicals. Grades: Highly Purified. CAS No. 946369-04-6. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C21H22ClN5O2, Molecular Weight: 411.88. US Biological Life Sciences. | Worldwide |
| Tgf-alpha | Tgf-alpha. Uses: Designed for use in research and industrial production. Additional or Alternative Names: HUMAN TRANSFORMING GROWTH FACTOR ALPHA;HUMAN TGF-A;HUMAN TGF-ALPHA;H-VAL-VAL-SER-HIS-PHE-ASN-LYS-CYS-PRO-ASP-SER-HIS-THR-GLN-TYR-CYS-PHE-HIS-GLY-THR-CYS-ARG-PHE-LEU-VAL-GLN-GLU-GLU-LYS-PRO-ALA-CYS-VAL-CYS-HIS-SER-GLY-TYR-VAL-GLY-VAL-ARG-CYS-GLU-HIS-ALA-A. Product Category: Heterocyclic Organic Compound. CAS No. 89899-53-6. Molecular formula: C244H367N71O71S6. Mole weight: 5623.35. Product ID: ACM89899536. Alfa Chemistry ISO 9001:2015 Certified. Categories: TGF alpha. | |
| TGF α (1-50) (rat) | TGF α (1-50) (rat) was originally identified as an agent that can reversibly confer a transformed phenotype on normal non-tumor cells, such as normal rat renal fibroblasts. This activity requires the presence of transforming growth factor-β (TGF-β), which enhances the effects of TGF-α through a separate receptor. TGF-α is synthesized by monocytes, keratinocytes and a variety of tissues and tumors. (approx. ED50 = 0.2 ng/mL). Synonyms: H-Val-Val-Ser-His-Phe-Asn-Lys-Cys-Pro-Asp-Ser-His-Thr-Gln-Tyr-Cys-Phe-His-Gly-Thr-Cys-Arg-Phe-Leu-Val-Gln-Glu-Glu-Lys-Pro-Ala-Cys-Val-Cys-His-Ser-Gly-Tyr-Val-Gly-Val-Arg-Cys-Glu-His-Ala-Asp-Leu-Leu-Ala-OH (Disulfide bridge: Cys8-Cys21, Cys16-Cys32, Cys34-Cys43); Transforming Growth Factor-α (1-50) from rat. CAS No. 89899-53-6. Molecular formula: C244H361N71O71S6. Mole weight: 5617.38. | |
| TGF-beta 3-E. coli human | recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| TGFβ-IN-2 | TGFβ-IN-2 (Compound 9d) inhibits TGF-β-induced total collagen accumulation in NRK-49F cells with the IC 50 of 4.31 μM. TGFβ-IN-2 suppresses the TGF-β-induced protein expression of COL1A1, α-SMA, and p-Smad3 in vitro. TGFβ-IN-2 can be used as a potential effective compound for anti-fibrosis in vivo by oral administration [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2387678-02-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-146434. | |
| TGFβ-IN-5 | TGFβ-IN-5(Compd 12) is a TGFβ inhibitor useful for the study of fibroproliferative diseases associated with TGF-β signaling [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 259870-32-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128437. | |
| TGF-beta receptor type-2 (131-139) | TGF-beta receptor type-2 (131-139) is a truncated fragment of TGF-beta receptor type-2. TGF-beta receptor type-2 is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with TGF-beta receptor type-1, and binds TGF-beta. Synonyms: Transforming Growth Factor Beta Receptor 2 (131-139); TGF-Beta Type II Receptor (131-139). | |
| TGF-beta/Smad Compound Library | A unique collection of 180 TGF-beta/Smad signaling targeted compounds for high throughput and high content screening; - Bioactivity and safety confirmed by pre-clinical research and clinical trials; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L4100. Categories: TGF-beta/Smad Compounds Libraries. |  |
| TGFBR1-IN-2 | TGFBR1-IN-2 (Compound AQA) is a TGFBR1 inhibitor and an antibacterial agent. TGFBR1-IN-2 is a substrate for cytochrome P450s. TGFBR1-IN-2 contains the pyridyl-6-methyl moiety necessary for Mycobacterium tuberculosis inhibition and has potent inhibitory activity against non-replicating and persistent Mycobacterium tuberculosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 733806-89-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-164793. | |
| TGF?R1 (80-end), active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| TGF?R1 (80-end), GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| TGF?R2 (190-end), active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| TGN 020 | TGN 020. Group: Biochemicals. Grades: Purified. CAS No. 51987-99-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TGN-020 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| TGN-020 | TGN-020 is a selective Aquaporin 4 (AQP4) inhibitor with an IC50 of 3.1 ?M[1][2]. TGN-020 is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[3].TGN-020 alleviates edema and inhibits glial scar formation after spinal cord compression injury in rats[4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 51987-99-6. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-W008574. | |
| TGN-020 sodium | TGN-020 sodium is a selective Aquaporin 4 (AQP4) inhibitor with an IC50 of 3.1 ?M[1][2]. TGN-020 sodium is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[3]. TGN-020 sodium alleviates edema and inhibits glial scar formation after spinal cord compression injury in rats[4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1313731-99-5. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-W008574A. | |
| TGR5 Receptor Agonist | TGR5 Receptor Agonist (CCDC), a potent Takeda G protein-coupled receptor 5 (TGR5; GPCR19) agonist, shows improved potency in the U2-OS cells and melanophore cells with pEC 50 s of 6.8 and 7.5, respectively. TGR5 Receptor Agonist can induce peripheral and central hypersensitivity to bladder distension in mice, and increase intracellular Ca 2+ concentration. TGR5 Receptor Agonist can also reduces food intake and improves insulin responsiveness, in diet-induced obese mice. TGR5 Receptor Agonist can be used to research diabetes, bladder hypersensitivity and anti-obesity [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CCDC. CAS No. 1197300-24-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14229. | |
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