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One of the impurities of Zolpidem, which is a GABAA receptor agonist and could be used as a hypnotic agent. Molecular formula: C13H16BrNO2. Mole weight: 298.18.
Zolpidem Related Compound 3
One of the impurities of Zolpidem, which is a GABAA receptor agonist and could be used as a hypnotic agent. Molecular formula: C13H15NO2. Mole weight: 217.27.
Zolpidem Related Compound 4
One of the impurities of Zolpidem, which is a GABAA receptor agonist and could be used as a hypnotic agent. Synonyms: 6-Methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetamide; Zolpidem Related Compound C. CAS No. 365213-58-7. Molecular formula: C17H17N3O. Mole weight: 279.34.
Zolpidem Related Compound 5
One of the impurities of Zolpidem, which is a GABAA receptor agonist and could be used as a hypnotic agent. Synonyms: 2-(4-Methylphenyl)-6-methylimidazole[1,2-a]-pyridine-3-acetic Acid; 6-Methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetic Acid; Zolpidic Acid; Zolpidem Acid. CAS No. 189005-44-5. Molecular formula: C17H16N2O2. Mole weight: 280.33.
Zolpidem USP Related Compound B
Zolpidem USP Related Compound B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 400038-68-8. Molecular Formula: C19H19N3O2. Mole Weight: 321.38. Catalog: APB400038688.
Zolpidem USP Related Compound C
Zolpidem USP Related Compound C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 14547-80-9. Molecular Formula: C13H12N2O. Mole Weight: 212.25. Catalog: APB14547809.
Zolunicant (18-Methoxycoronaridine)
Zolunicant (18-Methoxycoronaridine). Uses: For analytical and research use. Group: Impurity standards. CAS No. 188125-42-0. Molecular Formula: C22H28N2O3. Mole Weight: 368.48. Catalog: APB188125420.
Zomepirac-acyl-beta-D-Glucuronide
One of the Glucuronide-derived impurities of Zomepirac, which could be used as an anti-inflammatory as well as analgesic agent. Synonyms: 1-[5-(4-Chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetate] β-D-Glucopyranuronic Acid; Zomepirac Glucuronide; Zomepirac Acyl-1-O-β-D-glucuronide. CAS No. 75871-31-7. Molecular formula: C21H22ClNO9. Mole weight: 467.85.
Zomepirac Sodium
Zomepirac sodium salt is a prostaglandin synthetase inhibitor, was indicated for the management of mild to severe pain. Uses: An analgesic, anti-inflammatory drug. Synonyms: 5-(4-Chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetic Acid Sodium Salt; McN 2783-21-98; 2-[5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrol-2-yl]acetic acid. Grades: ≥98%. CAS No. 64092-48-4. Molecular formula: C15H13ClNNaO3. Mole weight: 313.71.
Zomepirac Sodium Salt
Zomepirac is an analgesic, anti-inflammatory drug. Group: Biochemicals. Alternative Names: 5-(4-Chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetic Acid Sodium Salt; McN 2783-21-98; Sodium Zomepirac; Zomax; Zomepirac Sodium; Zomepirac Sodium Salt. Grades: Highly Purified. CAS No. 64092-48-4. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Zomiradomide
KT-413 (example I-3) is an orally active PROTAC-class IRAK degrader [1]. KT-413 consists of a target protein ligand (red part) PROTAC IRAK4 ligand-5 (HY-168311), an E3 ubiquitin ligase ligand (blue part) Thalidomide-4-Br (HY-W039116), and a PROTAC linker (black part) 2-(2-Azaspiro[3.3]heptan-6-yl)ethanamine (HY-168313). E3 ubiquitin ligase and linker can form Thalidomide-NH-C2-2-azaspiro[3.3]heptane (HY-168312). The active control for the target protein ligand is RSL3-4-Me (HY-169375). Uses: Scientific research. Group: Signaling pathways. Alternative Names: KT-413. CAS No. 2655656-99-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153368.
Zomitriptan dimer
Zomitriptan dimer. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C38H49N7O4. Mole Weight: 667.86. Catalog: APB11213.
Zomitriptan EP impurity A
Zomitriptan EP impurity A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 139264-24-7. Molecular Formula: C16H21N3O2. Mole Weight: 287.36. Catalog: APB139264247.
Zomitriptan EP impurity B
Zomitriptan EP impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 251451-30-6. Molecular Formula: C16H21N3O3. Mole Weight: 303.36. Catalog: APB251451306.
Zomitriptan EP impurity D
Zomitriptan EP impurity D. Uses: For analytical and research use. Group: Impurity standards. CAS No. 139264-15-6. Molecular Formula: C14H17N3O2. Mole Weight: 259.31. Catalog: APB139264156.
Zomitriptan EP impurity E
Zomitriptan EP impurity E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 152305-23-2. Molecular Formula: C10H12N2O2. Mole Weight: 192.22. Catalog: APB152305232.
Zomitriptan EP impurity F
Zomitriptan EP impurity F. Uses: For analytical and research use. Group: Impurity standards. CAS No. 139264-69-0. Molecular Formula: C15H23N3O. Mole Weight: 261.37. Catalog: APB139264690.
Zomitriptan EP impurity G
Zomitriptan EP impurity G. Uses: For analytical and research use. Group: Impurity standards. CAS No. 139264-35-0. Molecular Formula: C15H19N3O2. Mole Weight: 273.34. Catalog: APB139264350.
Zomitriptan EP impurity H
Zomitriptan EP impurity H. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2518343-21-8. Molecular Formula: C16H19N3O2. Mole Weight: 285.35. Catalog: APB2518343218.
Zomitriptan EP impurity I
Zomitriptan EP impurity I. Uses: For analytical and research use. Group: Impurity standards. CAS No. 659738-69-9. Molecular Formula: C17H21N3O4. Mole Weight: 331.37. Catalog: APB659738699.
ZONATAC NG 98
ZONATAC NG 98. Group: Polymers.
Zongertinib
Zongertinib (BI 1810631) is a potent and selective HER2 and EGFR tyrosine kinase inhibitor with IC 50 values of 13 nM and 579 nM, respectively. Zongertinib has antitumor activity and can be used in the study of multiple solid tumors [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BI 1810631. CAS No. 2728667-27-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-148810.
Zoniporide
Zoniporide (CP-597396) is a potent and selective NHE-1 inhibitor with cardioprotective activity. Zoniporide inhibits 22 Na + uptake by human NHE-1 -expressing fibroblasts in a concentration-dependent manner ( IC 50 =14 nM). Zoniporide inhibits platelet swelling in vitro with an IC 50 of 0.059 μM. Zoniporide can be used in the study of cardiovascular disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-597396. CAS No. 241800-98-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-105064.
Zoniporide
Zoniporide, also called as CP-597,396, is a potent and selective Na(+)/H(+) exchanger (NHE) with high aqueous solubility and acceptable pharmacokinetics for intravenous administration. Zoniporide displays selectivity over other NHE isoforms (Ki values are 14, 2200 and 220000 nM for human NHE1, human NHE2 and rat NHE3 respectively). Synonyms: N-Carbamimidoyl-5-cyclopropyl-1-(quinolin-5-yl)-1H-pyrazole-4-carboxamide; N-(5-Cyclopropyl-1-quinolin-5-yl-1H-pyrazole-4-carbonyl)-guanidine. Grades: >98%. CAS No. 241800-98-6. Molecular formula: C17H16N6O. Mole weight: 320.35.
Zoniporide dihydrochloride
Zoniporide dihydrochloride is a potent sodium-hydrogen exchanger isoform 1 (NHE1) inhibitor with selectivity over other NHE isoforms (Ki = 14, 2200 and 220000 nM for human NHE1, human NHE2 and rat NHE3, respectively). Zoniporide inhibits NHE1-dependent 22Na+ uptake in vitro (IC50 = 14 nM) and protects against cardiac ischemia-reperfusion injury. Zoniporide also exhibits inhibitory effects on MMP2/9 in breast cancer cells. Synonyms: [1-(Quinolin-5-yl)-5-cyclopropyl-1H-pyrazole-4-carbonyl]guanidine dihydrochloride; CP 597396. Grades: ≥99% by HPLC. CAS No. 241799-10-0. Molecular formula: C17H16N6O.2HCl. Mole weight: 393.27.
Zoniporide hydrochloride
Zoniporide hydrochloride is a potent and selective inhibitor of Na+/H+ exchanger isoform 1 (NHE-1), which is mostly expressed in the heart. Zoniporide inhibits NHE1-dependent Na+ uptake (IC50: 14 nM) and protects from cardiac ischemia-reperfusion injury (EC50 = 0.25 nM). Synonyms: N-(aminoiminomethyl)-5-cyclopropyl-1-(5-quinolinyl)-1H-pyrazole-4-carboxamide monohydrochloride. Grades: 99%. CAS No. 241800-97-5. Molecular formula: C17H16N6O.HCl. Mole weight: 356.81.
Zoniporide Hydrochloride
Zoniporide is a potent and selective inhibitor of human sodium-hydrogen exchanger isoform1(NHE-1) and protects against cardiac ischemia-reperfusion injury. Group: Biochemicals. Alternative Names: N-(Aminoiminomethyl)-5-cyclopropyl-1-(5-quinolinyl)-1H-pyrazole-4-carboxamide Hydrochloride;CP 597396 Hydrochloride; N-[5-Cyclopropyl-1-(quinolin-5-yl)-1H-pyrazole-4-carbonyl]guanidine Hydrochloride; [1-(Quinolin-5-yl)-5-cyclopropyl-1H-pyrazole-4-carbonyl]guanidine Hydrochloride. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Zoniporide hydrochloride hydrate
Zoniporide (CP-597396) hydrochloride hydrate is a potent and selective inhibitor of sodium-hydrogen exchanger type 1 (NHE-1). Zoniporide hydrochloride hydrate inhibits human NHE-1 ( IC 50=14 nM), and has >150-fold selectivity versus other NHE isoforms. Zoniporide hydrochloride hydrate potently inhibits ex vivo NHE-1-dependent swelling of human platelets (IC 50 =59 nM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-597396 hydrochloride hydrate. CAS No. 863406-85-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105064D.
Zonisamid2-15C2-15N
13C Labeled Compounds. Alternative Names: 1,2-Benzisoxazole-13C2-3-methanesulfonamide-15N; 3-(Sulfamoyl-15N-methyl)-1,2-benzisoxazole-13C2; AD 810-13C2-15N; Aleviatin-13C2-15N; Excegran-13C2-15N; PD 110843-13C2-15N; Zonegran-13C2-15N. CAS No. 1188265-58-8. Molecular formula: C613C2H8N15NO3S. Mole weight: 215.2. Appearance: Off-White to Pale Yellow Solid. Catalog: ACM1188265588.
Zonisamide
Zonisamide is the first agent of this chemical class to be developed as an antiepileptic drug blocks repetitive firing of voltagesensitive sodium channels and reduces voltage-sensitive T-type calcium currents. Uses: Sulfonamide antiseizure agent; blocks repetitive firing of voltagesensitive sodium channels and reduces voltage-sensitive t-type calcium currents. heterocyclic methanesulfonide with anticonvulsant properties. the compound is under investigation for potent. Synonyms: AD-810; AD-810N; AD 810; AD 810N; AD810; AD810N; 1,2-Benzisoxazole-3-methanesulfonamide; 3-(Sulfamoylmethyl)-1,2-benzisoxazole. Grades: ≥98%. CAS No. 68291-97-4. Molecular formula: C8H8N2O3S. Mole weight: 212.23.
Zonisamide
Zonisamide (AD 810) is an orally active carbonic anhydrase inhibitor, with K i s of 35.2 and 20.6 nM for hCA II and hCA V , respectively. Zonisamide exerts neuroprotective effects through anti- apoptosis and upregulating MnSOD levels. Zonisamide also increases the expression of Hrd1 , thereby improving cardiac function in AAC rats. Zonisamide can be used in studies of seizure, parkinsons disease and cardiac hypertrophy [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AD 810; CI 912. CAS No. 68291-97-4. Pack Sizes: 10 mM * 1 mL; 200 mg; 500 mg. Product ID: HY-B0124.
Zonisamide
Zonisamide. Group: Biochemicals. Grades: Highly Purified. CAS No. 68291-97-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Heterocyclic methanesulfonide with anticonvulsant properties. The compound is under investigation for potential therapeutic use as an antiepileptic drug. Group: Biochemicals. Alternative Names: 1,2-Benzisoxazole-3-methanesulfonamide. Grades: Highly Purified. CAS No. 68291-97-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Zonisamide Acid
Zonisamide Acid. Uses: For analytical and research use. Group: Impurity standards. CAS No. 4865-84-3. Molecular Formula: C9H7NO3. Mole Weight: 177.16. Catalog: APB4865843.
A deuterated heterocyclic methanesulfonide with anticonvulsant properties. The compound is under investigation for potential therapeutic use as an antiepileptic drug. Group: Biochemicals. Alternative Names: 1,2-Benzisoxazole-3-methanesulfonamide-d4. Grades: Highly Purified. CAS No. 1020720-04-0. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Zonisamide-N-(6-hexanoic Acid)
Zonisamide derivative. Group: Biochemicals. Alternative Names: ZNS Carboxylic Acid; 6- [ [ (1, 2-Benzisoxazol-3-ylmethyl) sulfonyl] amino] hexanoic Acid. Grades: Highly Purified. CAS No. 1076199-51-3. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Zonisamide N,N-Dimethylformimidamide
Zonisamide related compound C. Group: Biochemicals. Alternative Names: (N)-Benzisox-3-ylmethylsulfonyl)-N,N-dimethylformimidamide. Grades: Highly Purified. CAS No. 1217201-89-2. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Zonisamide sodium salt
Zonisamide is the first agent of this chemical class to be developed as an antiepileptic drug blocks repetitive firing of voltagesensitive sodium channels and reduces voltage-sensitive T-type calcium currents. Uses: Sulfonamide antiseizure agent; blocks repetitive firing of voltagesensitive sodium channels and reduces voltage-sensitive t-type calcium currents. heterocyclic methanesulfonide with anticonvulsant properties. the compound is under investigation for potent. Synonyms: 1,2-benzisoxazole-3-methanesulfonamide sodium-potassium salt;1,2-Benzisoxazole-3-methanesulfonamide sodium-potassium salt, Aleviatin sodium-potassium salt, Exceglan. Grades: ≥98%. CAS No. 68291-98-5. Molecular formula: C8H7N2NaO3S. Mole weight: 234.21.
Z-Onsu
Z-Onsu. Group: Biochemicals. Alternative Names: N-Benzyl oxycarbonyl oxysuccinimide . Grades: Highly Purified. CAS No. 13139-17-8. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C12H11NO5. US Biological Life Sciences.
Worldwide
ZONYL FS-300
ZONYL FS-300 is a fluorosurfactant known for its ability to reduce liquid surface tension and provide unique properties such as excellent wetting, spreading and leveling capabilities. Uses: Zonyl fs-300 fluorosurfactant designed for industrial applications including coatings, inks, adhesives and cleaning products. it is a nonionic fluorosurfactant, which means it is electrically neutral and contains no charged groups. this feature makes it compatible with a variety of formulations. CAS No. 197664-69-0. Molecular formula: RfCH2CH2O(CH2CH2O)xH. Appearance: liquid. Purity: 0.96. Density: 1.10±0.05 g/mL at 20 °C. Catalog: ACM197664690.
ZONYL(R) FSO
Heterocyclic Organic Compound. Alternative Names: ZONYL(R) FSO. CAS No. 101027-76-3. Purity: 0.96. Density: 1.20 g/mL±0.05 g/mL at 20 °C. Catalog: ACM101027763.
ZONYL(R) TBS, NH(4)(+)-FORM
Heterocyclic Organic Compound. CAS No. 111019-20-6. Purity: 0.96. Catalog: ACM111019206.
Zopiclone
Cyclopyrrolone member of a family of non-benzodiazepine GABAA receptor agonists. This is a controlled substance (depressant) in the US but not in Canada. Sedative, hypnotic. Group: Biochemicals. Alternative Names: 4-Methyl-1-piperazine-carboxylic Acid 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl Ester; RP-27267; Amoban; Imovane; Limovan; Sopivan; Ximovan; Zimovane. Grades: Highly Purified. CAS No. 43200-80-2. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C17H17ClN6O3. US Biological Life Sciences.
Worldwide
Zopiclone-d8
Cyclopyrrolone member of a family of non-benzodiazepine GABAA receptor agonists. This is a controlled substance (depressant) in the US but not in Canada. Sedative, hypnotic. Group: Biochemicals. Alternative Names: 4-Methyl-1-piperazine-d8-carboxylic Acid 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl Ester; RP-27267-d8; Amoban-d8; Imovane-d8; Limovan-d8; Sopivan-d8; Ximovan-d8; Zimovane. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Zopiclone-d8 N-Oxide. (Mixture of diastereomers) (1-Piperazine-d8-carboxylic Acid 4-Methyl-4-oxide 6-(5-Chloro-pyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5yl Ester,. RP 29753-d8)
A labeled metabolite of Zopiclone. Group: Biochemicals. Alternative Names: 1-Piperazine-d8-carboxylic Acid 4-Methyl-4-oxide 6-(5-Chloro-pyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5yl Ester;RP 29753-d8. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Zopiclone Deschloro Impurity
One of the impurities of Zopiclone, which is a GABAA receptor agonist and could be used as a sedative as well as hypnotic agent. Synonyms: Deschloro-Zopiclone. CAS No. 1348046-61-6. Molecular formula: C17H18N6O3. Mole weight: 354.37.
Zopiclone Impurity 15
Zopiclone Impurity 15. Uses: For analytical and research use. Group: Impurity standards. CAS No. 4180-30-7. Molecular Formula: C11H22N4O. Mole Weight: 226.32. Catalog: APB4180307.
Zopiclone Impurity 2
Zopiclone Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1122549-43-2. Molecular Formula: C11H9ClN4O2. Mole Weight: 264.67. Catalog: APB1122549432.
One of the impurities of Zopiclone, which is a GABAA receptor agonist and could be used as a sedative as well as hypnotic agent. Synonyms: 3-Formyl-2-Pyrazinecarboxylic Acid. Molecular formula: C6H4N2O3. Mole weight: 152.11.
One of the impurities of Zopiclone, which is a GABAA receptor agonist and could be used as a sedative as well as hypnotic agent. Synonyms: 5-(Chloropyridine-2-yl-carbamoyl)pyrazine. Molecular formula: C10H7ClN4O. Mole weight: 234.65.
Zopiclone Impurity A
One of the impurities of Zopiclone, which is a GABAA receptor agonist and could be used as a sedative as well as hypnotic agent. Synonyms: Zopiclone N-Oxide; 1-Piperazine-carboxylic Acid 4-Methyl-4-oxide 6-(5-Chloro-pyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5yl Ester; RP 29753; Eszopiclone Impurity A. CAS No. 43200-96-0. Molecular formula: C17H17ClN6O4. Mole weight: 404.82.
Zopiclone N-Oxide (Eszopiclone Impurity A)
Eszopiclone impurity A. Group: Biochemicals. Alternative Names: 1-Piperazine-carboxylic Acid 4-Methyl-4-oxide 6-(5-Chloro-pyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5yl Ester;RP 29753; Eszopiclone Impurity A. Grades: Highly Purified. CAS No. 43200-96-0. Pack Sizes: 5mg. US Biological Life Sciences.
Zopolrestat is an inhibitor of Aldose Reductase(AR). It has been shown to play roles in inflammation and cancer. It is used for the treatment of diabetic nephropathy and cardiac disease. It was developed by Pfizer and was terminated in clinic phase 2 trials. Uses: Zopolrestat is used for the treatment of diabetic nephropathy and cardiac disease. Synonyms: 3-[(5-Trifluoromethyl-2-benzothiazolyl)methyl]-3,4-dihydro-4-oxophthalazine-1-acetic acid;CP-73850;3,4-Dihydro-4-oxo-3-[[5-(trifluoromethyl)-2-benzothiazolyl]methyl]-1-phthalazineacetic acid;Alond;Xedia;2-[4-Oxo-3-[[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl]phthalazin-1-yl]acetic acid;CP 73850; CP73850; CP-73850; Zopolrestat; Zopolrestatum. Grades: 95%. CAS No. 110703-94-1. Molecular formula: C19H12F3N3O3S. Mole weight: 419.38.
Zorifertinib
Zorifertinib (AZD3759) is a potent, orally active, central nervous system-penetrant, EGFR inhibitor. At K m ATP concentrations, the IC 50 s are 0.3, 0.2, and 0.2 nM for EGFR wt , EGFR L858R , and EGFR exon 19Del , respectively. Zorifertinib induces cancer cell apoptosis. Zorifertinib has antitumor activity, and can be used for NSCLC, HCC etc. research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD3759. CAS No. 1626387-80-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18750.
Zorubicin is a benzoyl-hydrazone derivative of the anthracycline antineoplastic antibiotic daunorubicin. Zorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. Synonyms: RP-22050; RP 22050; RP22050; Zorubicine; N'- (1-{ (2S, 4S) -4-[ (3-Amino-2, 3, 6-trideoxy-α -L-lyxo-hexopyranosyl) oxy]-2, 5, 12-trihydroxy-7-methoxy-6, 11-dioxo-1, 2, 3, 4, 6, 11-hexahydro-2-tetracenyl}ethylidene) benzohydrazide; Rubidazone; Benzoic acid hydrazide, 3-hydrazone with daunorubicin; Benzoic acid, (1-(4-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl)ethylidene)hydrazide, (2S-cis)-; Benzoic acid, 2-[1-[(2S,4S)-4-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl]ethylidene]hydrazide; Daunomycin benzoylhydrazone; MCMC 4222; Rubidazon. Grades: ≥95%. CAS No. 54083-22-6. Molecular formula: C34H35N3O10. Mole weight: 645.66.
Zosuquidar
Zosuquidar, also called as LY335979, a cyclopropyldibenzosuberane, was developed as an inhibitor of P-glycoprotein (P-gp). It is undergoing testing in a phase I/II trial clinical study in acute myeloid leukaemia. Synonyms: (2R)-anti-5-(3-(4-(10,11-difluoromethanodibenzo-suber-5-yl)piperazin-1-yl)2-hydroxypropoxy)quinoline trihydrochlorideLY 335979; LY-335979LY335979RS 33295-198RS-33295-198zosuquidar trihydrochloride. CAS No. 167354-41-8. Molecular formula: C32H31F2N3O2. Mole weight: 527.60.
Zosuquidar
Zosuquidar (LY335979) is a P-glycoprotein (P-gp) inhibitor ( K i =59 nM). Zosuquidar shows anti-tumor activities, and can be used in acute myelogenous leukemia (AML) research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RS 33295-198; LY-335979. CAS No. 167354-41-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-15255.
Zosuquidar trihydrochloride
Zosuquidar (LY335979) is a potent modulator of P-glycoprotein-mediated multi-drug resistance with a Ki value of 60 nM. Synonyms: LY 335979; LY-335979; D06387; RS-33295-198; Zosuquidar HCl. CAS No. 167465-36-3. Molecular formula: C32H34Cl3F2N3O2. Mole weight: 636.99.
Zosurabalpin is a polypeptide antibiotic targeting LPS transporter (LptB 2 FGC complex), which can block the transport of LPS and lead to endotoxin accumulation in cells, and has shown excellent antibacterial activity against Carbapenem-resistant Acinetobacter baumanni (CRAB) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Abx MCP; RG6006. CAS No. 2379336-76-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147429.
Zotarolimus
Zotarolimus (ABT-578) is a derivative of Rapamycin (HY-10219), with anti-proliferative activity. Zotarolimus is an immunosuppressant. Zotarolimus is developed specifically for local delivery from stents for the prevention of coronary artery restenosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-578; A 179578. CAS No. 221877-54-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-12424.
Zotarolimus
Zotarolimus, also known as ABT-578 and A-179578, is an immunosuppressant. It is a semi-synthetic derivative of rapamycin. It was designed for use in stents with phosphorylcholine as a carrier. Coronary stents reduce early complications and improve late clinical outcomes in patients needing interventional cardiology. Medtronic are using zotarolimus as the anti-proliferative agent in the polymer coating of their Endeavor and Resolute products. Group: Inhibitors. Alternative Names: A-179578; A 179578; A179578; ABT578; ABT-578; ABT 578; Endeavor; Zotarolimus; Rapamycin, 42-deoxy-42-(1H-tetrazol-1-yl)-, (42S)-. CAS No. 221877-54-9. Molecular formula: C52H79N5O12. Mole weight: 966.23. Appearance: Solid powder. Purity: >95%. IUPACName: (3S, 6R, 7E, 9R, 10R, 12R, 14S, 15E, 17E, 19E, 21S, 23S, 26R, 27R, 34aS)-9, 27-dihydroxy-10, 21-dimethoxy-3-{(1R)-2-[(1S, 3R, 4S)-3-methoxy-4-(1H-tetrazol-1-yl)cyclohexyl]-1-methylethyl}-6, 8, 12, 14, 20, 26-hexamethyl-4, 9, 10, 12, 13, 14, 21, 22, 23, 24, 25, 26, 27, 32, 33, 34, 34a-heptadecahydro-3H-23, 27-epoxypyrido[2, 1-c][1, 4]oxazacyclohentriacontine-1, 5, 11, 28, 29(6H, 31H)-pentone. Canonical SMILES: O=C ([C@@] (CCCC1) ([H])N1C (C ([C@@]2 (O)[C@H] (C)CC[C@@] (O2) ([H])C[C@H] (OC)/C (C)=C/C=C/C=C/[C@@H] (C)C[C@@H] (C)C ([C@H] (OC)[C@H] (O)/C (C)=C/[C@H]3C)=O)=O)=O)O[C@H] ([C@H] (C)C[C@H]4C[C@@H] (OC)[C@@H] (N5N=NN=C5)CC4)CC3=O. Catalog: ACM221877549.
Zotarolimus
Zotarolimus (also known as ABT-578) is an analogue of rapamycin (sirolimus) that was designed to have a shorter in vivo half-life than rapamycin. Zotarolimus was found to be comparable in potency for inhibiting in vitro proliferation of both rat and human T cells and mechanistically similar to sirolimus in having high-affinity binding to the immunophilin FKBP12. Zotarolimus is a semi-synthetic derivative of rapamycin. It was designed for use in stents with phosphorylcholine as a carrier. Group: Biochemicals. Alternative Names: 40-epi-(N1-Tetrazolyl)-rapamycin; ABT-578; KY 12420. Grades: Highly Purified. CAS No. 221877-54-9. Pack Sizes: 1mg, 5mg. US Biological Life Sciences.
Worldwide
Zotarolimus
Zotarolimus (INN, codenamed ABT-578) is an immunosuppressant. It is a semi-synthetic derivative of rapamycin. It was designed for use in stents with phosphorylcholine as a carrier. Coronary stents reduce early complications and improve late clinical outcomes in patients needing interventional cardiology. Synonyms: A-179578; A 179578; A179578; ABT-578; ABT578; ABT 578. Grades: >98%. CAS No. 221877-54-9. Molecular formula: C52H79N5O12. Mole weight: 966.21.
Zotatifin
Zotatifin (eFT226) is a potent, selective, and well-tolerated eIF4A inhibitor. Zotatifin promotes eIF4A binding to specific mRNA sequences with recognition motifs in the 5-UTRs ( IC 50 =2 nM) and interferes with the assembly of the eIF4F initiation complex [1]. Zotatifin shows robust antiviral effects, it effectively reduces viral infectivity by inhibiting SARS-CoV-2 NP protein biogenesis ( IC 90 =37 nM) [2]. Zotatifin induces cell apoptosis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: eFT226. CAS No. 2098191-53-6. Pack Sizes: 1 mg; 2 mg; 5 mg; 10 mg. Product ID: HY-112163.
Zotepine
Zotepine. Group: Biochemicals. Grades: Highly Purified. CAS No. 26615-21-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Zotepine
Zotepine is a 5-HT2A receptor and dopamine D2 receptor antagonist (Ki = 0.69 and 2.3 nM, respectively) used as an atypical antipsychotic for the treatment of schizophrenia. Zotepine also exhibits an antagonistic effect at histamine H1 receptor (IC50 = 8.0 nM). Uses: Antipsychotic agents. Synonyms: 2-[(8-Chlorodibenzo(Z)[b,f]thiepin-10-yl)oxy]-N,N-dimethylethanamine; Nipolept; Lodopin; Zoleptil; Zotepina. Grades: ≥99% by HPLC. CAS No. 26615-21-4. Molecular formula: C18H18ClNOS. Mole weight: 331.86.