A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
One of the impurities of Zopiclone, which is a GABAA receptor agonist and could be used as a sedative as well as hypnotic agent. Synonyms: 3-Formyl-2-Pyrazinecarboxylic Acid. Molecular formula: C6H4N2O3. Mole weight: 152.11.
One of the impurities of Zopiclone, which is a GABAA receptor agonist and could be used as a sedative as well as hypnotic agent. Synonyms: 5-(Chloropyridine-2-yl-carbamoyl)pyrazine. Molecular formula: C10H7ClN4O. Mole weight: 234.65.
Zopiclone Impurity A
One of the impurities of Zopiclone, which is a GABAA receptor agonist and could be used as a sedative as well as hypnotic agent. Synonyms: Zopiclone N-Oxide; 1-Piperazine-carboxylic Acid 4-Methyl-4-oxide 6-(5-Chloro-pyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5yl Ester; RP 29753; Eszopiclone Impurity A. CAS No. 43200-96-0. Molecular formula: C17H17ClN6O4. Mole weight: 404.82.
Zopiclone N-Oxide (Eszopiclone Impurity A)
Eszopiclone impurity A. Group: Biochemicals. Alternative Names: 1-Piperazine-carboxylic Acid 4-Methyl-4-oxide 6-(5-Chloro-pyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5yl Ester;RP 29753; Eszopiclone Impurity A. Grades: Highly Purified. CAS No. 43200-96-0. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Zopolrestat
Zopolrestat is an inhibitor of Aldose Reductase(AR). It has been shown to play roles in inflammation and cancer. It is used for the treatment of diabetic nephropathy and cardiac disease. It was developed by Pfizer and was terminated in clinic phase 2 trials. Uses: Zopolrestat is used for the treatment of diabetic nephropathy and cardiac disease. Synonyms: 3-[(5-Trifluoromethyl-2-benzothiazolyl)methyl]-3,4-dihydro-4-oxophthalazine-1-acetic acid;CP-73850;3,4-Dihydro-4-oxo-3-[[5-(trifluoromethyl)-2-benzothiazolyl]methyl]-1-phthalazineacetic acid;Alond;Xedia;2-[4-Oxo-3-[[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl]phthalazin-1-yl]acetic acid;CP 73850; CP73850; CP-73850; Zopolrestat; Zopolrestatum. Grades: 95%. CAS No. 110703-94-1. Molecular formula: C19H12F3N3O3S. Mole weight: 419.38.
Zorevunersen sodium is an antisense oligonucleotide that is intended to increase the level of productive SCN1A mRNA and consequently increase the expression of the sodium channel Nav1.1 protein. Zorevunersen sodium is used for the study of Dravet syndrome. Uses: Scientific research. Group: Signaling pathways. Alternative Names: STK-001 sodium. CAS No. 2415330-05-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148410A.
Zorifertinib
Zorifertinib (AZD3759) is a potent, orally active, central nervous system-penetrant, EGFR inhibitor. At K m ATP concentrations, the IC 50 s are 0.3, 0.2, and 0.2 nM for EGFR wt , EGFR L858R , and EGFR exon 19Del , respectively. Zorifertinib induces cancer cell apoptosis. Zorifertinib has antitumor activity, and can be used for NSCLC, HCC etc. research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD3759. CAS No. 1626387-80-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18750.
Zorubicin is a benzoyl-hydrazone derivative of the anthracycline antineoplastic antibiotic daunorubicin. Zorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. Synonyms: RP-22050; RP 22050; RP22050; Zorubicine; N'- (1-{ (2S, 4S) -4-[ (3-Amino-2, 3, 6-trideoxy-α -L-lyxo-hexopyranosyl) oxy]-2, 5, 12-trihydroxy-7-methoxy-6, 11-dioxo-1, 2, 3, 4, 6, 11-hexahydro-2-tetracenyl}ethylidene) benzohydrazide; Rubidazone; Benzoic acid hydrazide, 3-hydrazone with daunorubicin; Benzoic acid, (1-(4-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl)ethylidene)hydrazide, (2S-cis)-; Benzoic acid, 2-[1-[(2S,4S)-4-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl]ethylidene]hydrazide; Daunomycin benzoylhydrazone; MCMC 4222; Rubidazon. Grades: ≥95%. CAS No. 54083-22-6. Molecular formula: C34H35N3O10. Mole weight: 645.66.
Zosuquidar
Zosuquidar, also called as LY335979, a cyclopropyldibenzosuberane, was developed as an inhibitor of P-glycoprotein (P-gp). It is undergoing testing in a phase I/II trial clinical study in acute myeloid leukaemia. Synonyms: (2R)-anti-5-(3-(4-(10,11-difluoromethanodibenzo-suber-5-yl)piperazin-1-yl)2-hydroxypropoxy)quinoline trihydrochlorideLY 335979; LY-335979LY335979RS 33295-198RS-33295-198zosuquidar trihydrochloride. CAS No. 167354-41-8. Molecular formula: C32H31F2N3O2. Mole weight: 527.60.
Zosuquidar
Zosuquidar (LY335979) is a P-glycoprotein (P-gp) inhibitor ( K i =59 nM). Zosuquidar shows anti-tumor activities, and can be used in acute myelogenous leukemia (AML) research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RS 33295-198; LY-335979. CAS No. 167354-41-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-15255.
Zosuquidar (LY335979) trihydrochloride is a P-glycoprotein (P-gp) inhibitor (Ki=59 nM). Zosuquidar trihydrochloride shows anti-tumor activities, and can be used in acute myelogenous leukemia (AML) research[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RS 33295-198 trihydrochloride; LY-335979 trihydrochloride. CAS No. 167465-36-3. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50671.
Zosuquidar trihydrochloride
Zosuquidar (LY335979) is a potent modulator of P-glycoprotein-mediated multi-drug resistance with a Ki value of 60 nM. Synonyms: LY 335979; LY-335979; D06387; RS-33295-198; Zosuquidar HCl. CAS No. 167465-36-3. Molecular formula: C32H34Cl3F2N3O2. Mole weight: 636.99.
Zosurabalpin is a polypeptide antibiotic targeting LPS transporter (LptB 2 FGC complex), which can block the transport of LPS and lead to endotoxin accumulation in cells, and has shown excellent antibacterial activity against Carbapenem-resistant Acinetobacter baumanni (CRAB) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Abx MCP; RG6006. CAS No. 2379336-76-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147429.
Zotarolimus
Zotarolimus (INN, codenamed ABT-578) is an immunosuppressant. It is a semi-synthetic derivative of rapamycin. It was designed for use in stents with phosphorylcholine as a carrier. Coronary stents reduce early complications and improve late clinical outcomes in patients needing interventional cardiology. Synonyms: A-179578; A 179578; A179578; ABT-578; ABT578; ABT 578. Grades: >98%. CAS No. 221877-54-9. Molecular formula: C52H79N5O12. Mole weight: 966.21.
Zotarolimus
Zotarolimus (ABT-578) is a derivative of Rapamycin (HY-10219), with anti-proliferative activity. Zotarolimus is an immunosuppressant. Zotarolimus is developed specifically for local delivery from stents for the prevention of coronary artery restenosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-578; A 179578. CAS No. 221877-54-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-12424.
Zotarolimus
Zotarolimus, also known as ABT-578 and A-179578, is an immunosuppressant. It is a semi-synthetic derivative of rapamycin. It was designed for use in stents with phosphorylcholine as a carrier. Coronary stents reduce early complications and improve late clinical outcomes in patients needing interventional cardiology. Medtronic are using zotarolimus as the anti-proliferative agent in the polymer coating of their Endeavor and Resolute products. Uses: Designed for use in research and industrial production. Additional or Alternative Names: A-179578; A 179578; A179578; ABT578; ABT-578; ABT 578; Endeavor; Zotarolimus; Rapamycin, 42-deoxy-42-(1H-tetrazol-1-yl)-, (42S)-. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 221877-54-9. Molecular formula: C52H79N5O12. Mole weight: 966.23. Purity: >95%. IUPACName: (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-10,21-dimethoxy-3-{(1R)-2-[(1S,3R,4S)-3-methoxy-4-(1H-tetrazol-1-yl)cyclohexyl]-1-methylethyl}-6,8,12,14,20,26-hexamethyl-4,9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-heptadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(6H,31H)-pentone. Canonical SMILES: O=C([C@@](CCCC1)([H])N1C(C([C@@]2(O)[C@H](C)CC[C@@](O2)([H])C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C([C@H](OC)[C@H](O)/C(C)=C/[C@H]3C)=O)=O)=O)O[C@H]([C@H](C)C[C@H]4C[C@@H](OC)[C@@H](N5N=NN=C5)CC4)CC3=O. Product ID: ACM221877549. Alfa Chemistry ISO
Zotarolimus (also known as ABT-578) is an analogue of rapamycin (sirolimus) that was designed to have a shorter in vivo half-life than rapamycin. Zotarolimus was found to be comparable in potency for inhibiting in vitro proliferation of both rat and human T cells and mechanistically similar to sirolimus in having high-affinity binding to the immunophilin FKBP12. Zotarolimus is a semi-synthetic derivative of rapamycin. It was designed for use in stents with phosphorylcholine as a carrier. Group: Biochemicals. Alternative Names: 40-epi-(N1-Tetrazolyl)-rapamycin; ABT-578; KY 12420. Grades: Highly Purified. CAS No. 221877-54-9. Pack Sizes: 1mg, 5mg. US Biological Life Sciences.
Worldwide
Zotatifin
Zotatifin (eFT226) is a potent, selective, and well-tolerated eIF4A inhibitor. Zotatifin promotes eIF4A binding to specific mRNA sequences with recognition motifs in the 5-UTRs ( IC 50 =2 nM) and interferes with the assembly of the eIF4F initiation complex [1]. Zotatifin shows robust antiviral effects, it effectively reduces viral infectivity by inhibiting SARS-CoV-2 NP protein biogenesis ( IC 90 =37 nM) [2]. Zotatifin induces cell apoptosis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: eFT226. CAS No. 2098191-53-6. Pack Sizes: 1 mg; 2 mg; 5 mg; 10 mg. Product ID: HY-112163.
Zotepine
Zotepine is a 5-HT2A receptor and dopamine D2 receptor antagonist (Ki = 0.69 and 2.3 nM, respectively) used as an atypical antipsychotic for the treatment of schizophrenia. Zotepine also exhibits an antagonistic effect at histamine H1 receptor (IC50 = 8.0 nM). Uses: Antipsychotic agents. Synonyms: 2-[(8-Chlorodibenzo(Z)[b,f]thiepin-10-yl)oxy]-N,N-dimethylethanamine; Nipolept; Lodopin; Zoleptil; Zotepina. Grades: ≥99% by HPLC. CAS No. 26615-21-4. Molecular formula: C18H18ClNOS. Mole weight: 331.86.
Zotepine. Group: Biochemicals. Grades: Highly Purified. CAS No. 26615-21-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Zotepine
Zotepine, an antipsychotic agent, is a potent antagonist of 5-HT 2A , 5-HT 2C , Histamine H 1 , α 1 -adrenergic and Dopamine D 2 receptors , with K d s of 2.6 nM, 3.2 nM, 3.3 nM, 7.3 nM and 8 nM, respectively. Zotepine exhibits antidepressive and anxiolytic effects in vivo [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 26615-21-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-103093.
Zotepine impurity 3
Zotepine impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1514918-29-6. Molecular formula: C18H18ClNO3S. Mole weight: 363.86. Catalog: APB1514918296.
Zotepine impurity 9
Zotepine impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 133884-20-5. Molecular formula: C16H18ClNOS. Mole weight: 307.84. Catalog: APB133884205.
Z-O-tert-butyl-D-allo-threonine cyclohexylammonium salt
Z-O-tert-butyl-D-allo-threonine cyclohexylammonium salt. Group: Biochemicals. Alternative Names: Z-D-allo-Thr(tBu)-OH·DCHA. Grades: Highly Purified. CAS No. 100157-55-9. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences.
Worldwide
Z-O-tert-butyl-D-allo-threonine cyclohexylammonium salt 99+% (GC)
Z-O-tert-butyl-D-allo-threonine cyclohexylammonium salt 99+% (GC). Group: Biochemicals. Grades: GC. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences.