A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
8-Nitro-7-methylaminoquinoline. Group: Biochemicals. Alternative Names: N-Methyl-8-nitro-7-quinolinamine; 7-Methylamino-8-nitroquinoline. Grades: Highly Purified. CAS No. 147293-16-1. Pack Sizes: 100mg. US Biological Life Sciences.
8-Nitroguanine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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8-Nitroguanine
8-Nitroguanine is a nitrative guanine derivative formed by oxidative damage to the guanine base in DNA by reactive nitrogen species (RNS) during inflammation and in vitro by reaction of DNA with peroxynitrite and other RNS reagents. Synonyms: 2-Amino-8-nitro-7H-purin-6-ol. Grades: ≥95%. CAS No. 168701-80-2. Molecular formula: C5H4N6O3. Mole weight: 196.1.
8-Nitroguanosine
A highly reactive redox-active nucleic acid derivative that is is formed in cellular RNA as biomarker of exposure to reactive nitrogen species. Recent studies suggest that it might contribute to the pathogenesis of inflammation-associated carcinogenesis. Group: Biochemicals. Grades: Highly Purified. CAS No. 337536-53-5. Pack Sizes: 10mg. US Biological Life Sciences.
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8-Nitroguanosine
A highly reactive redox-active nucleic acid derivative that is formed in cellular RNA as biomarker of exposure to reactive nitrogen species. Recent studies suggest that it might contribute to the pathogenesis of inflammation-associated carcinogenesis. Synonyms: 8-Nitro-D-guanosine; 2-imino-8-nitro-9-(beta-D-ribofuranosyl)-3,9-dihydro-2H-purin-6-ol; 2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-nitro-1H-purin-6(9H)-one. Grades: ≥95%. CAS No. 337536-53-5. Molecular formula: C10H12N6O7. Mole weight: 328.24.
8-Nitroguanosine 2',3',5'-Triacetate
8-Nitroguanosine derivative. Used as chemical probes in protein S-guanylation by endogenous nitrated nucleosides. Synonyms: 8-Nitroguanosine 2',3',5'-Triacetate; 1096020-95-9; [(2R,3R,4R,5R)-3,4-diacetyloxy-5-(2-amino-8-nitro-6-oxo-1H-purin-9-yl)oxolan-2-yl]methyl acetate; (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2-amino-8-nitro-6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-3,4-diyl diacetate; J-002308; [(2R,3R,4R,5R)-3,4-bis(acetyloxy)-5-(2-amino-8-nitro-6-oxo-6,9-dihydro-1H-purin-9-yl)oxolan-2-yl]methyl acetate. CAS No. 1096020-95-9. Molecular formula: C16H18N6O10. Mole weight: 454.35.
8-Nitroguanosine 2',3',5'-Triacetate
8-Nitroguanosine (N496050) derivative. Used as chemical probes in protein S-guanylation by endogenous nitrated nucleosides. Group: Biochemicals. Grades: Highly Purified. CAS No. 1096020-95-9. Pack Sizes: 25mg. US Biological Life Sciences.
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8-Nitronaphthalene-1,3,6-trisulfonic acid
8-Nitronaphthalene-1,3,6-trisulfonic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 38267-31-1. Pack Sizes: 5g, 10g. US Biological Life Sciences.
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8-Nitroquinoline
8-Nitroquinoline. Group: Biochemicals. Grades: Highly Purified. CAS No. 607-35-3. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C9H6N2O2. US Biological Life Sciences.
8-(N,N-Diethylamino)octan-1-ol. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
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8-(N,N-Dimethylaminomethyl)guanosine
8-(N,N-Dimethylaminomethyl)guanosine is a profound compound, aiding in studying the unparalleled menace of herpes simplex virus (HSV) and human cytomegalovirus (HCMV). Grades: ≥95%. Molecular formula: C13H20N6O5. Mole weight: 340.34.
8-NO2-Guo
8-NO2-Guo is used for analysis of hydrolysates of RNA stressed by nitric oxide/superoxide and peroxynitrite. Synonyms: 8- Nitroguanosine. Grades: ≥ 98% by HPLC. CAS No. 337636-63-6. Molecular formula: C10H12N6O7. Mole weight: 328.3.
8-Nonenoic Acid
Nonenoic Acid. CAS No. 31642-67-8. Categories: 8-nonenoic acidnon-8-enoic acid.
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8-O-Acetylharpagide
8-O-Acetylharpagide. Group: Biochemicals. CAS No. 6926-14-3. Pack Sizes: 5mg. US Biological Life Sciences.
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8-O-Acetyl shanzhiside methyl ester
8-O-Acetyl shanzhiside methyl ester. Group: Biochemicals. Alternative Names: Barlerin; Umbroside. Grades: Plant Grade. CAS No. 57420-46-9. Pack Sizes: 20mg. Molecular Formula: C19H28O12, Molecular Weight: 448.418. US Biological Life Sciences.
Acoforestinine can be found in the root of Aconitum carmichaeli Debx. Synonyms: ACOFORESTININE; (1alpha, 3alpha, 6alpha, 14alpha, 16beta)-8-Ethoxy-20-ethyl-1, 6, 16-trimethoxy-4-(methoxymethyl)aconitane-3, 13, 14-triol 14-(4-methoxybenzoate). Grades: >98%. CAS No. 110011-77-3. Molecular formula: C35H51NO10. Mole weight: 645.79.
8-OH-2'-O-Me-cAMP
8-OH-2'-O-Me-cAMP is an activator of the exchange protein activated by cAMP (Epac) or cAMP-GEF, which does not activate protein kinase A. It can be used in patch clamp applications. Synonyms: 8- Hydroxy- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. Molecular formula: C11H13N5O7P · Na. Mole weight: 381.2.
8-OH-Ado
8-OH-Ado is used for analysis of oxidative/radioactive stress RNA hydrolysates. Synonyms: 8- Hydroxyadenosine. Grades: ≥ 97% by HPLC. CAS No. 29861-67-8. Molecular formula: C10H13N6O6. Mole weight: 283.3.
8-OH-cAMP
8-OH-cAMP is a polar analogue of cAMP used for the study of extracellular cAMP receptors. When applied by patch clamp techniques, 8-OH-cAMP remains trapped inside the cell. It exhibits a resistant effect of mammalian cyclic nucleotide-dependent phosphodiesterases. Synonyms: 8- Hydroxyadenosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 31356-95-3. Molecular formula: C10H11N5O7P · Na. Mole weight: 367.2.
8-OH-cGMP
8-OH-cGMP is a cyclic guanosine monophosphate (cGMP) analog used in biomedical research. It acts as a second messenger in signal transduction pathways. 8-OH-cGMP is mainly utilized for studying the role of cGMP in various cellular processes, including smooth muscle relaxation, cell proliferation, and neurotransmission. It is also commonly used to investigate the pathophysiology and potential therapeutic targets in diseases related to altered cGMP signaling, such as hypertension, cardiovascular disorders, and neurodegenerative diseases. Synonyms: 8- Hydroxyguanosine- 3', 5'- cyclic monophosphate. CAS No. 21082-28-0. Molecular formula: C10H11N5O8P · Na. Mole weight: 383.2.
8-OH-DPAT
8-OH-DPAT (8-Hydroxy-DPAT) is an agonist that has selectivity for 5-HT1A receptor (pIC50 = 8.19). It was subsequently found to be a serotonin reuptake inhibitor and a 5-HT7 receptor agonist as well. Studies showed that it exhibited antidepressant, anxiolytic and other properties. Uses: Serotonin receptor agonists. Synonyms: 8-HYDROXY-2-(DI-n-PROPYLAMINO)TETRALIN; 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol; CHEMBL56; Ro-31-8220 in solution; 8-Hydroxy-DPAT. Grades: 99.03 %. CAS No. 78950-78-4. Molecular formula: C16H25NO. Mole weight: 247.38.
8-OH-DPAT
8-OH-DPAT is a potent and selective 5-HT agonist, with a pIC 50 of 8.19 for 5-HT1A and a K i of 466 nM for 5-HT7; 8-OH-DPAT weakly binds to 5-HT1B (pIC 50 , 5.42), 5-HT (pIC 50 <5). Uses: Scientific research. Group: Signaling pathways. Alternative Names: 8-Hydroxy-DPAT. CAS No. 78950-78-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112061.
8-OH-DPAT hydrobromide
8-OH-DPAT (8-Hydroxy-DPAT) hydrobromide is a potent and selective 5-HT 1A agonist with a pIC 50 of 8.19. 8-OH-DPAT hydrobromide has selectivity of almost 1000 fold for a subtype of the 5-HT 1 binding site [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 8-Hydroxy-DPAT hydrobromide. CAS No. 76135-31-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15688.
8-Oxa-3-azabicyclo[3, 2, 1]octane hydrochloride. Group: Biochemicals. Grades: Highly Purified. CAS No. 54745-74-3. Pack Sizes: 100mg, 250mg, 500mg, 1g. US Biological Life Sciences.
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8-Oxa-3-thiabicyclo[5.1.0]octane(9ci)
Heterocyclic Organic Compound. CAS No. 115187-02-5. Catalog: ACM115187025.
8-Oxo-2'-deoxyadenosine
8-Oxo-2'-deoxyadenosine is a crucial product in the biomedical industry used for studying and treating oxidative DNA damage caused by reactive oxygen species. It is a modified form of the nucleoside adenosine and serves as a biomarker for DNA damage and oxidative stress-related diseases like cancer, neurodegenerative disorders, and cardiovascular diseases. Synonyms: 2'-Deoxy-8-oxo-adenosine;8-Oxo-dA; 6-AMINO-9-[(2R,4S,5R)-4-HYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-7H-PURIN-8-ONE; 8-Oxo-7,8-dihydro-2'-deoxyadenosine; 8-Oxo-deoxyadenosine; 8-hydroxy-2'-deoxyadenosine;6-amino-9-[(4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-7H-purin-8-one. Grades: ≥ 95%. CAS No. 62471-63-0. Molecular formula: C10H13N5O4. Mole weight: 267.24.
8-Oxo-2-deoxyadenosine
8-Oxo-2-deoxyadenosine. Group: Biochemicals. Alternative Names: 2'-Deoxy-7,8-dihydro-8-oxo-adenosine; 2'-Deoxy-7,8-dihydroadenosin-8-one; 7,8-Dihydro-8-oxodeoxyadenosine; 8-Oxo-2'-deoxyadenosine; 8-Oxo-2'-deoxydihydroadenosine; 8-Oxo-7,8-dihydro-2'-deoxyadenosine. Grades: Highly Purified. CAS No. 62471-63-0. Pack Sizes: 10mg. Molecular Formula: C10H13N5O4, Molecular Weight: 267.24. US Biological Life Sciences.
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8-Oxo-2-deoxyadenosine-13C2,15N
Isotope Labelled 8-Oxo-2-deoxyadenosine is the first example of a native DNA lesion that stabilizes human telomeric G-quadruplex DNA. Group: Biochemicals. Alternative Names: 2'-Deoxy-7,8-dihydro-8-oxo-adenosine-13C2,15N; 2'-Deoxy-7,8-dihydroadenosin-8-one-13C2,15N; 7,8-Dihydro-8-oxodeoxyadenosine-13C2,15N; 8-Oxo-2'-deoxyadenosine-13C2,15N; 8-Oxo-2'-deoxydihydroadenosine-13C2,15N; 8-Oxo-7,8-dihydro-2'-deoxyadenosine-13C2,15N. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
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8-Oxo-2'-deoxyguanosine
8-Oxo-2'-deoxyguanosine is a crucial biomarker to evaluate oxidative DNA damage in research of related diseases such as cancer and neurodegenerative disorders. It is an oxidized nucleoside known for its ability to accurately measure the level of oxidative stress. Synonyms: 8-Oxo-dG; 8-Hydroxy-2'-deoxyguanosine; 8-Hydroxydeoxyguanosine. Grades: ≥ 98%. CAS No. 88847-89-6. Molecular formula: C10H13N5O5. Mole weight: 283.24.
8-Oxo-2-deoxyguanosine-13C,15N2
A marker compound indicative of DNA damage associated with mutagenesis and carcinogenesis. Can induce differentiation of Friend murine erythroleukemia cells in vitro. Group: Biochemicals. Alternative Names: 8-Hydroxy-2-deoxyguanosine-13C,15N2; 8-Oxo-7,8-dihydrodeoxyguanosine-13C,15N2; 2'-Deoxy-7,8-dihydro-8-oxo-guanosine-13C,15N2; 8-Oxo-7,8-dihydro-2'-deoxyguanosine-13C,15N2; 8-Oxo-dG-13C,15N2. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
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8-Oxo-2'-deoxyguanosine 5'-Triphosphate Triethylamine Salt
8-Oxo-2'-deoxyguanosine-5'-Triphosphate, considered mutagenic dNTPs, it can be incorporated into DNA by PCR using standard Taq polymerase. Synonyms: 2'-Deoxy-7,8-dihydro-8-oxo-guanosine 5'-(tetrahydrogen triphosphate) Triethylamine Salt; 8-Hydroxy-2'-deoxyguanosine 5'-triphosphate Triethylamine Salt; 8-Oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate Triethylamine Salt; 8-Oxo-dGTP Triethylamine Salt; 8-Oxo-deoxyguanosine triphosphate Triethylamine Salt. Molecular formula: C10H16N5O14P3 xC6H15N. Mole weight: 523.18.
8-Oxo-2-deoxyguanosine (8-Hydroxy-2-deoxyguanosine). Group: Biochemicals. Alternative Names: 8-Hydroxy-2-deoxyguanosine. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
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8-Oxo-7-thioguanosine
8-Oxo-7-thioguanosine. Group: Biochemicals. Grades: Highly Purified. CAS No. 122970-43-8. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C10H12N4O6S. US Biological Life Sciences.
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8-Oxoadenoosine-5'-Triphosphate
8-Oxoadenosine-5'-Triphosphate, an ATP analog crucial for cell signaling and energy transfer, is integral to studying signal transduction pathways and disease mechanisms. It also aids in the DNA sequencing and mutagenesis studies through its ability to incorporate into DNA strands. Its widespread use in research has contributed to unravelling the mysteries hidden within cancer, inflammation, and neurological disorders. Synonyms: 8-Oxo-ATP; 8-Oxo-Adenosine-5'-Triphosphate. Grades: ≥95% by AX-HPLC. CAS No. 68745-44-8. Molecular formula: C10H16N5O14P3. Mole weight: 523.10.
8-Oxoadenosine
It is an anticancer antibiotic, oxidized nucleic acid adduct and phosmidosine precursor (P-prodrug). It can be used to treat hemochromatosis. Synonyms: NSC 102240; NSC 90396; 7,8-Dihydro-8-oxoadenosine; 8-Hydroxyadenosine; 8-Oxo-7,8-dihydroadenosine; 6-Amino-7,9-dihydro-9-β-D-ribofuranosyl-8H-purin-8-one; 6-amino-9-(beta-D-ribofuranosyl)purin-8-(7H)-one; (2R,3R,4S,5R)-2-(6-amino-8-hydroxy-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 8-Hydroxyadenosine. Grades: ≥95%. CAS No. 29851-57-8. Molecular formula: C10H13N5O5. Mole weight: 283.24.
8-Oxo-Benzylguanine
8-Oxo-Benzylguanine is a derivative of O-Benzylguanine, an reversible inhibitor of the mammalian DNA repair protein, O6-alkylguanine-DNA alkyltransferase. O-Benzylguanine is known to assists in the protection against carcinogenic and therapeutic alkylating agents. Group: Biochemicals. Alternative Names: 2-Amino-7,9-dihydro-6-(phenylmethoxy)-8H-purin-8-one; NU 6043. Grades: Highly Purified. CAS No. 158754-46-2. Pack Sizes: 50mg. US Biological Life Sciences.
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8-Oxo-Benzylguanine
As a derivative of O-Benzylguanine, 8-Oxo-Benzylguanine is a reversible inhibitor of the mammalian DNA repair protein, O6-alkylguanine-DNA alkyltransferase and O-Benzylguanine is known to assist in the protection against carcinogenic and therapeutic alkylating agents. Synonyms: 2-Amino-7,9-dihydro-6-(phenylmethoxy)-8H-purin-8-one; NU 6043. CAS No. 158754-46-2. Molecular formula: C12H11N5O2. Mole weight: 257.25.
8-oxocoformycin reductase
Si-specific with respect to NADPH. Also reduces 8-oxodeoxy-coformycin to the nucleoside antibiotic deoxycoformycin. Group: Enzymes. Synonyms: 8-ketodeoxycoformycin reductase. Enzyme Commission Number: EC 1.1.1.235. CAS No. 114995-16-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0142; 8-oxocoformycin reductase; EC 1.1.1.235; 114995-16-3; 8-ketodeoxycoformycin reductase. Cat No: EXWM-0142.
8-Oxo-dATP
8-Oxo-dATP is a nucleotide analog mainly acting as a substrate for DNA polymerase during DNA enhancement and repair. 8-Oxo-dATP is involved in cellular processes related to oxidative stress and DNA damage. It can be used to study the effects of oxidative DNA damage and its association with diseases such as cancer and neurodegenerative disorders. Synonyms: 8-Oxo-2'-deoxyadenosine-5'-Triphosphate; 8-Hydroxy-2'-deoxyadenosine 5'-triphosphoric acid. Grades: ≥ 95% by HPLC. Molecular formula: C10H16N5O13P3 (free acid). Mole weight: 507.18 (free acid).
8-Oxo-desacetylated famciclovir
An impurity of Famciclovir. Famciclovir is used for the treatment of various herpesvirus infections, most commonly for herpes zoster. Synonyms: 4-(2-amino-8-oxo-7H-purin-9(8H)-yl)-2-(hydroxymethyl)butyl acetate. Grades: > 95%. Molecular formula: C12H17N5O4. Mole weight: 295.30.
8-oxo-dG-CE Phosphoramidite
8-oxo-dG-CE Phosphoramidite is an indispensable compound assuming a pivotal role in oligonucleotide research and development. Its contributes to the exploration of therapeutic drugs aimed at DNA repair and ailments associated with oxidative stress. Synonyms: 5'-Dimethoxytrityl-N2-isobutyryl-8-oxo-deoxyGuanosine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Grades: 95%. CAS No. 143060-53-1. Molecular formula: C44H54N7O9P. Mole weight: 855.93.
8-Oxo-dGDP
8-Oxo-dGDP, a nucleotide analog, serves as a substrate for DNA polymerases and as a regulator for those enzymes associated with DNA repair in biochemical studies. Furthermore, it is employed to explore the involvement of oxidative stress in cancer and neurodegenerative diseases, such as Alzheimer's and Parkinson's. Synonyms: 8-Oxo-2'-deoxyguanosine-5'-diphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H15N5O11P2 (free acid). Mole weight: 443.20 (free acid).
8-oxo-dGDP phosphatase
The enzyme catalyses the hydrolysis of both 8-oxo-dGDP and 8-oxo-GDP thereby preventing translational errors caused by oxidative damage. The preferred in vivo substrate is not known. The enzyme does not degrade 8-oxo-dGTP and 8-oxo-GTP to the monophosphates (cf. EC 3.6.1.55, 8-oxo-dGTP diphosphatase). Ribonucleotide diphosphates and deoxyribonucleotide diphosphates are hydrolysed with broad specificity. The bifunctional enzyme NUDT5 also hydrolyses ADP-ribose to AMP and D-ribose 5-phosphate (cf. EC 3.6.1.13, ADP-ribose diphosphatase). The human enzyme NUDT18 also hydrolyses 8-oxo-dADP and 2-hydroxy-dADP, the latter at a slower rate. Group: Enzymes. Synonyms: NUDT5; MTH3 (gene name); NUDT18. Enzyme Commission Number: EC 3.6.1.58. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4630; 8-oxo-dGDP phosphatase; EC 3.6.1.58; NUDT5; MTH3 (gene name); NUDT18. Cat No: EXWM-4630.
8-Oxo-dGMP
8-Oxo-dGMP is a nucleotide derivative commonly used in research to study DNA damage and repair mechanisms. It is often used to detect and quantify oxidation damage to DNA induced by reactive oxygen species, as well as to investigate the role of 8-oxo-dG in mutagenesis and carcinogenesis. 8-Oxo-dGMP has potential therapeutic applications for the treatment of diseases associated with oxidative stress, such as cancer and neurodegenerative disorders. Synonyms: 8-Oxo-2'-deoxyguanosine-5'-monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H14N5O8P (free acid). Mole weight: 363.22 (free acid).
8-Oxo-dGP4
8-Oxo-dGP4 is a chemical compound used in biomedical research for the study of DNA damage and repair mechanisms. It is a modified form of the nucleoside guanosine and is commonly utilized to identify and quantify oxidative damage to DNA caused by reactive oxygen species. Additionally, 8-Oxo-dGP4 has potential in the development and screening of drugs for the treatment of diseases related to DNA damage, such as cancer and neurodegenerative disorders. Synonyms: 8-Oxo-2'-deoxyguanosine-5'-tetraphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H17N5O17P4 (free acid). Mole weight: 603.16 (free acid).
8-Oxo-dGTP
8-Oxo-dGTP can increase the rate of genetic mutation via interfering with the function of nucleic acids. A clastogen is a specific mutagen that causes breaks in chromosomes. Uses: 8-oxo-dgtp is an agent that increase the rate of genetic mutation. Synonyms: 8-Oxo-2'-deoxyguanosine-5'-Triphosphate; 8-Oxodeoxyguanosine triphosphate; 8-Oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate. Grades: ≥95% by AX-HPLC. CAS No. 139307-94-1. Molecular formula: C10H16N5O14P3 (free acid). Mole weight: 523.18 (free acid).
8-oxo-dGTP diphosphatase
This enzyme hydrolyses the phosphoanhydride bond between the α and β phosphate of 8-oxoguanine-containing nucleoside di- and triphosphates thereby preventing misincorporation of the oxidized purine nucleoside triphosphates into DNA. It does not hydrolyse 2-hydroxy-dATP (cf. EC 3.6.1.56, 2-hydroxy-dATP diphosphatase). Requires Mg2+. Group: Enzymes. Synonyms: MutT; 7,8-dihydro-8-oxoguanine triphosphatase; 8-oxo-dGTPase; 7,8-dihydro-8-oxo-dGTP pyrophosphohydrolase. Enzyme Commission Number: EC 3.6.1.55. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4627; 8-oxo-dGTP diphosphatase; EC 3.6.1.55; MutT; 7,8-dihydro-8-oxoguanine triphosphatase; 8-oxo-dGTPase; 7,8-dihydro-8-oxo-dGTP pyrophosphohydrolase. Cat No: EXWM-4627.
8-Oxoepiberberine
8-Oxoepiberberine is a protoberberine alkaloid that inhibits polymerization of DNA, RNA and proteins. It also has an inhibitory effect on the replication of pertussis toxin. 8-Oxoepiberberine has been shown to have anti-cancer properties in vitro and in vivo. This drug inhibits tumor growth by inhibiting cell proliferation and inducing apoptosis. 8-Oxoepiberberine also inhibits the growth of primary tumors in mice without affecting normal cells or healthy tissue. This drug is also effective against lung cancer cells and has been shown to be safe for use in humans. Group: Other alkaloids. CAS No. 19716-60-0. Molecular formula: C20H17NO5. Mole weight: 351.4 g/mol. Canonical SMILES: COC1=C (C=C2C (=C1)CCN3C2=CC4=C (C3=O)C5=C (C=C4)OCO5)OC. Catalog: ACM19716600-1.
8-Oxoepiberberine
8-Oxoepiberberine is an alkaloid metabolite in the plasma after oral administration of Zuojin formula, a traditional chinese medicine used to treat gastrointestinal disease [1]. Uses: Scientific research. Group: Natural products. CAS No. 19716-60-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N4173.
8-Oxo-GTP
8-Oxo-GTP, a nucleotide with modifications, is a valuable tool in discovering RNA oxidative and repair mechanisms. Its versatile use also includes investigations into Alzheimer's and Parkinson's, as well as cancer. Its potential to provide antioxidant properties demonstrates promise for defending against oxidative stress in various disease states. Synonyms: 8-Oxoguanosine-5'-Triphosphate. Grades: ≥ 95% by HPLC. CAS No. 21238-36-8. Molecular formula: C10H16N5O15P3 (free acid). Mole weight: 539.18 (free acid).
8-oxoguanine deaminase
Zn2+ is bound in the active site. 8-Oxoguanine is formed via the oxidation of guanine within DNA by reactive oxygen species. If uncorrected, this modification leads to the incorporation of 8-oxoG:A mismatches and eventually to G:C to T:A transversions. Group: Enzymes. Synonyms: 8-OGD. Enzyme Commission Number: EC 3.5.4.32. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4560; 8-oxoguanine deaminase; EC 3.5.4.32; 8-OGD. Cat No: EXWM-4560.
An 8-oxo-guanine repair pathway coordinated by MUTYH glycosylase and DNA polymerase lambda. Group: Biochemicals. Alternative Names: 8-Hydroxyguanine Hydrochloride; 2-Amino-6,8-dihydroxypurine Hydrochloride. Grades: Highly Purified. Pack Sizes: 500mg. US Biological Life Sciences.
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8-Oxoguanosine
8-Oxoguanosine. Group: Biochemicals. Alternative Names: 8-Hydroxy-D-guanosine. Grades: Highly Purified. CAS No. 3868-31-3. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C10H13N5O6. US Biological Life Sciences.
Worldwide
8-Oxo-N2-isobutyryl-2'-deoxyguanosine
8-Oxo-N2-isobutyryl-2'-deoxyguanosine is an exceptional biomedical compound, rendered as a discerning indicator for DNA impairment. It assumes an integral role as a substrate for DNA reparation. Its utilization propels extensive investigation into oxidative species-induced DNA lesions, thereby furnishing profound elucidation into an array of afflictions spanning cancer to neurodegenerative disorders. Synonyms: 8-HYDROXY-N2-ISOBUTRYL-2'-DEOXYGUANOSINE; 8-HYDROXY-N2-ISOBUTRYL-2/'-DEOXYGUANOSINE; N-[9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,8-dioxo-1,7-dihydropurin-2-yl]-2-methylpropanamide; DTXSID40721580; MFCD22373349; N2-Isobutyryl-8-oxo-2'-deoxyguanosine; 2'-Deoxy-N-(2-methylpropanoyl)-8-oxo-7,8-dihydroguanosine; N-(8-hydroxy-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide. Grades: ≥ 90%. CAS No. 136859-76-2. Molecular formula: C14H19N5O6. Mole weight: 353.33.
8-pCPT-2'-O-Me-5'-AMP
8-pCPT-2'-O-Me-5'-AMP is a potential metabolite of 8-pCPT-2'-O-Me-cAMP, the specific Epac activator. Synonyms: 8-(4-Chlorophenylthio)-2'-O-methyladenosine-5'-O-monophosphate, sodium salt. Grades: ≥ 97% by HPLC. CAS No. 1187179-94-7. Molecular formula: C17H19ClN5O7PS (free acid). Mole weight: 503.85 (free acid).