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| Product | Description | |
|---|---|---|
| Avermectin B1a aglycone | It is an acid degradation product produced by hydrolysis of the disaccharide unit of avermectin. It is an inhibitor of nematode larval development. It has no paralytic activity. It is an anthelmintic in animal health. Synonyms: (6R,13S,25R)-22,23-didehydro-5-O-demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl]-milbemycin B. Grades: >95% by HPLC. CAS No. 71828-14-3. Molecular formula: C34H48O8. Mole weight: 584.74. |  |
| Avermectin b1a ≥95% (HPLC) | Avermectin b1a ≥95% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 2.5g. US Biological Life Sciences. |  Worldwide |
| Avermectin B1a monosaccharide | It is an acid degradation product produced by selective hydrolysis of the terminal saccharide unit of avermectin. It is a potent inhibitor of nematode larval development. It has no paralytic activity. Synonyms: 4'-O-de(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-5-O-demethyl-avermectin A1a; 5-O-Demethyl-4'-O-de(2,6-dideoxy-3-O-methyl-α-L-glucopyranosyl)avermectin A1a; MSB 1a. Grades: >95% by HPLC. CAS No. 71831-09-9. Molecular formula: C41H60O11. Mole weight: 728.91. | |
| Avermectin B1b (Antibiotic C 076B1b) | Avermectin B1b is the minor component (<20%) of the commerically available anthelmintic marketed as Abamectin(R) used to control parasitic nematodes in livestock. Avermectin B1b contains a isopropyl residue in the 24-position. In vitro and in vivo studies have shown this analogue to be active but less potent than the B1a analogue. Group: Biochemicals. Alternative Names: Antibiotic C 076B1b. Grades: Highly Purified. CAS No. 65195-56-4. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Avermectin B2a | Avermectin B2a is produced by the strain of Streptomyces avermitilis. It stimulates nerve cells to release Y-aminobutyric acid (GABA), which blocks the transmission of signals from the central nervous system to the motor nerve. It is not resistant to bacteria and fungi, but has strong activity to nematode parasites such as ancylostoma and Pteria, as well as insects such as flies. Abamectin B1a has the highest activity. Ivermectin obtained by catalytic hydrogenation contains 22 23- dihydroabamectin B1a (above 80%) and 22 23 dioxabamectin B1b (below 20%). Less active than B1a but less toxic. Used as repellent (subcutaneous or oral) for cattle, sheep and pigs, it is also effective against human filariasis. Synonyms: SCHEMBL1681286. CAS No. 65195-57-5. Molecular formula: C48H74O15. Mole weight: 891.09. | |
| avermitilol synthase | Requires Mg2+. The recombinent enzyme gives avermitilol (85%) plus traces of germacrene A, germacrene B and viridiflorol. The (1S)-hydrogen of farnesyl diphosphate is retained. Group: Enzymes. Enzyme Commission Number: EC 4.2.3.96. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5260; avermitilol synthase; EC 4.2.3.96. Cat No: EXWM-5260. |  |
| Averufin | Averufin is produced by the strain of Asergillus sp. Ames tests showed a weak mutagenic effect. Synonyms: Averufine; 3,4,5,6-Tetrahydro-7,9,11-trihydroxy-2-methyl-2,6-epoxy-2H-anthra[2,3-b]oxocin-8,13-dione. CAS No. 14016-29-6. Molecular formula: C20H16O7. Mole weight: 368.34. | |
| a-Vi-5 | a-Vi-5. Uses: Designed for use in research and industrial production. Additional or Alternative Names: A-VI-5;Bradykinin potentiating factor alpha-vi-5. Product Category: Heterocyclic Organic Compound. CAS No. 39194-96-2. Molecular formula: C22H40N6O10. Mole weight: 548.59. Purity: 0.96. IUPACName: 6-amino-2-[[2-[[2-[[2-[(2-amino-3-methylbutanoyl)amino]-5-hydroxy-5-oxopentanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxypropanoyl]amino]hexanoic acid. Canonical SMILES: CC(C)C(C(=O)NC(CCC(=O)O)C(=O)NC(CO)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)O)N. Density: 1.34g/cm³. Product ID: ACM39194962. Alfa Chemistry ISO 9001:2015 Certified. Categories: A-Vi-Pel. |  |
| Avian Eggshell Membrane Collagen | Avian Eggshell Membrane Collagen. |  CA, FL & NJ |
| Avibactam | Avibactam is a novel investigational non-beta-lactam beta-lactamase inhibitor that is being developed for possible use in combination with ceftaroline in the U.S. Avibactam does not have any intrinsic antibacterial activity in its own right, but appears to be capable of inhibiting beta-lactamase enzymes that belong to molecular classes A and C.Avibactam is useful for Antibiotics. Uses: Beta-lactamase inhibitors. Synonyms: Sulfuric acid mono[(1R,2S,5R)-2-(aminocarbonyl)-7-oxo-1,6-diazabicyclo[3.2.1]oct-6-yl] ester; Avibactam free acid; [(2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl] hydrogen sulfate. Grades: >98%. CAS No. 1192500-31-4. Molecular formula: C7H11N3O6S. Mole weight: 265.24. | |
| Avibactam free acid | Avibactam (NXL-104) free acid is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC 50 s of 8 nM and 5 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NXL-104 free acid. CAS No. 1192500-31-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14879. |  |
| Avibactam Impurity 11 | Avibactam Impurity 11 is an impurity of Avibactam. Synonyms: Avibactam Impurity 11; 1416134-60-5; Ethyl 5-phenylmethoxyiminopiperidine-2-carboxylate; Avibactam Impurity 15; (S,E)-ethyl 5-((benzyloxy)imino)piperidine-2-carboxylate. Grades: > 95%. CAS No. 1416134-60-5. Molecular formula: C14H18N2O3. Mole weight: 262.31. | |
| Avibactam Impurity 27 | Avibactam Impurity 27. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2S,5R)-ethyl 5-((benzyloxy)amino)piperidine-2-carboxylate oxalate. CAS No. 1416134-48-9. Molecular formula: C17H24N2O7. Mole weight: 368.38. Catalog: APB1416134489. |  |
| Avibactam Impurity 3 | Avibactam Impurity 3 is an impurity of Avibactam. Synonyms: (2S,5R)-5-[(benzyloxy)amino]piperidine-2-carboxamide; 2-Piperidinecarboxamide, 5-[(phenylmethoxy)amino]-, (2S,5R)-; (2S,5R)-5-(benzyloxyamino)-piperidine-2-carboxylic acid amide; 5R-(5-Benzyloxyamino) L-Pipecolic Amide. Grades: > 95%. CAS No. 1416134-49-0. Molecular formula: C13H19N3O2. Mole weight: 249.32. | |
| Avibactam Impurity 49 | Avibactam Impurity 49. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1416134-73-0. Molecular formula: C14H20N2O3. Mole weight: 264.33. Catalog: APB1416134730. | |
| Avibactam Impurity 6 | An impurity of Avibactam, a non-β lactam β-lactamase inhibitor that inactivates some β-lactamases. Synonyms: (2S,5R)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (1R,2S,5R)-7-Oxo-6-(phenylmethoxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide. Grades: >95%. CAS No. 1192651-49-2. Molecular formula: C14H17N3O3. Mole weight: 275.31. | |
| Avibactam Impurity 77 | Avibactam Impurity 77. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2S,5R)-ethyl 6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxylate. CAS No. 1416134-63-8. Molecular formula: C16H20N2O4. Mole weight: 304.14. Catalog: APB1416134638. | |
| Avibactam Impurity 9 | Avibactam Impurity 9 is an impurity of Avibactam. Synonyms: Avibactam Intermediate; (2S,5R)-5-[(Phenylmethoxy)amino]-2-piperidinecarboxylic Acid Ethyl Ester Ethanedioate; (2S,5R)-Ethyl 5-((benzyloxy)amino)piperidine-2-carboxylate Oxalate. Grades: > 95%. CAS No. 1416134-48-9. Molecular formula: C17H24N2O7. Mole weight: 377.39. | |
| Avibactam Impurity N | Avibactam Impurity N. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2S,5R)-5-((benzyloxy)amino)piperidine-2-carboxamide. CAS No. 1416134-49-0. Molecular formula: C13H19N3O2. Mole weight: 249.31. Catalog: APB1416134490. | |
| Avibactam sodium | Avibactam sodium (NXL-104) is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC 50 s of 8 nM and 5 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NXL-104. CAS No. 1192491-61-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-14879A. | |
| Avibactam sodium | 100mg Pack Size. Group: Antibiotics, Bioactive Small Molecules, Research Organics & Inorganics. Formula: C7H10N3O6S ·Na. CAS No. 1192491-61-4. Prepack ID 90023818-100mg. Molecular Weight 287.2. See USA prepack pricing. |  |
| Avibactam Sodium, (+)- | An impurity of Avibactam, a non-β lactam β-lactamase inhibitor that inactivates some β-lactamases. Synonyms: (2R,5S)-7-Oxo-6-(sulfooxy)-1,6-diazabicyclo(3.2.1)octane-2-carboxamide monosodium salt. Grades: ≥95%. CAS No. 1383814-68-3. Molecular formula: C7H10N3NaO6S. Mole weight: 287.23. | |
| Avibactam sodium hydrate | Avibactam sodium (NXL-104) hydrate is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC 50 s of 8 nM and 5 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NXL-104 hydrate. CAS No. 2938989-90-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-14879B. | |
| Avibactam Sodium Salt | Avibactam Sodium Salt, a novel non-?-lactam ?-lactamase inhibitor, binds covalently to Ambler class A ?-lactamases, including KPCs, Ambler class C and some class D b-lactamases. In combination with ceftazidime, Avibactam is a new drug application for avibactam , and was approved by the FDA on February 25, 2015, to treat complicated urinary tract and complicated intra-abdominal Infections caused by antibiotic resistant-pathogens. Avibactam has limited intrinsic antimicrobial activity but restores the in vitro activity of b-lactams including ceftazidime, ceftaroline, the active metabolite of ceftaroline fosamil, and aztreonam against ESBL-producing pathogens. Synonyms: sodium (2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[321]octan-6-yl sulfate; NXL104; NXL-104; NXL 104; Avibactam; Avibactam sodium. CAS No. 1192491-61-4. Molecular formula: C7H10N3NaO6S. Mole weight: 287.23. | |
| Avibactam tomilopil | Avibactam tomilopil (ARX-1796, AV-006) is an orally active prodrug of Avibactam and a β-lactamase inhibitor. Avibactam tomilopil can be used in the study of diseases such as urinary tract infections [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ARX-1796; AV-006. CAS No. 2245880-46-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132987. | |
| Avicularin | Avicularin is an orally active flavonoid. Avicularin inhibits NF-κB (p65), COX-2 and PPAR-γ activities. Avicularin has anti-inflammatory, anti-infectious anti-allergic, anti-oxidant, hepatoprotective, and anti-tumor activities. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Yellow powder. CAS No. 572-30-5. Molecular formula: C20H18O11. Mole weight: 434.4. Purity: 0.98. IUPACName: 3-[(2S,3R,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychromen-4-one. Canonical SMILES: C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(O4)CO)O)O)O)O. Product ID: ACM572305. Alfa Chemistry ISO 9001:2015 Certified. | |
| Avicularin | Avicularin. Group: Biochemicals. Alternative Names: Avicularoside; Fenicularin. Grades: Plant Grade. CAS No. 572-30-5. Pack Sizes: 20mg. Molecular Formula: C20H18O11, Molecular Weight: 434.35. US Biological Life Sciences. | Worldwide |
| Avicularin | Avicularin is an orally active flavonoid. Avicularin inhibits NF-κB (p65) , COX-2 and PPAR-γ activities. Avicularin has anti-inflammatory, anti-infectious anti-allergic, anti-oxidant, hepatoprotective, and anti-tumor activities [1] [3]. Uses: Scientific research. Group: Natural products. CAS No. 572-30-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0222. | |
| Avidin?Agarose from egg white | aqueous glycerol suspension. Group: Fluorescence/luminescence spectroscopy. | |
| Avidin-Alkaline Phosphatase | buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Avidin, chiken egg white | Avidin, chicken egg white is a glycoprotein derived from egg protein. Avidin, chicken egg white has excellent affinity with biotin and is often used in combination with biotin for immunoassays to detect the location of antigens in tissues [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 1405-69-2. Pack Sizes: 5 mg. Product ID: HY-NP005. | |
| Avidin-ferritin labeled | avidin from egg white, lyophilized powder. Group: Fluorescence/luminescence spectroscopy. | |
| Avidinorubicin | Avidinorubicin is produced by the strain of Streptomyces avidinii. It has anti-gram positive and negative bacterial activity, and has cytotoxicity to tumor cells. Molecular formula: C60H86N4O22. Mole weight: 1215.34. | |
| Avidin?Sulforhodamine 101 | lyophilized powder. Group: Fluorescence/luminescence spectroscopy. | |
| Aviglycine hydrochloride | Aviglycine hydrochloride (ABG-3168) is an inhibitor of ethylene biosynthesis. The use of Aviglycine hydrochloride (ABG-3168) delays the natural flowering of pineapples, reduces fruit drop, and maintains fruit firmness [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABG-3168. CAS No. 55720-26-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W009861. | |
| Avilamycin (~80%) | Avilamycin is an antimicrobial agent used against methicillin resistant Staphylococcus. Group: Biochemicals. Alternative Names: LY 048740; Maxus; Maxus 100; Maxus 200; Surmax. Grades: Highly Purified. CAS No. 11051-71-1. Pack Sizes: 5mg, 25mg. Molecular Formula: C??H??Cl?O??, Molecular Weight: 1404.24. US Biological Life Sciences. | Worldwide |
| Avilamycin A | Avilamycin A is produced by the strain of Streptomyces viridochromogenes NRRL 2860. It inhibits the binding of amino acid-based tRNA to the bacterial ribosome for 30S subunit and has anti-gram-positive bacterial activity. It has been tried as feed additive in animal feeding. Synonyms: Flambamycin, 23-deoxy-. CAS No. 69787-79-7. Molecular formula: C61H88Cl2O32. Mole weight: 1404.23. | |
| Avilamycin B | Avilamycin B is produced by the strain of Streptomyces viridochromogenes NRRL 2860. It inhibits the binding of amino acid-based tRNA to the bacterial ribosome for 30S subunit and has anti-gram-positive bacterial activity. It has been tried as feed additive in animal feeding. Grades: 95%. CAS No. 73240-30-9. Molecular formula: C59H84Cl2O32. Mole weight: 1376.19. | |
| Avilamycin C | Avilamycin C is produced by the strain of Streptomyces viridochromogenes NRRL 2860. It inhibits the binding of amino acid-based tRNA to the bacterial ribosome for 30S subunit and has anti-gram-positive bacterial activity. It has been tried as feed additive in animal feeding. Synonyms: SCHEMBL6753731. Grades: 95%. CAS No. 69787-80-0. Molecular formula: C61H90Cl2O32. Mole weight: 1406.25. | |
| Aviptadil | Aviptadil Acetate is an analog of vasoactive intestinal polypeptide (VIP) as Vasoactive intestinal peptide receptor agonists for the treatment of erectile dysfunction. Uses: Vasoactive intestinal peptide receptor agonists. Synonyms: H-His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2. Grades: 98%. CAS No. 40077-57-4. Molecular formula: C147H238N44O42S. Mole weight: 3325.80. | |
| Aviptadil | Aviptadil is an analog vasoactive intestinal polypeptide (VIP) with potent vasodilatory effects. Aviptadil induces pulmonary vasodilation and inhibits vascular SMCs proliferation, platelet aggregation. Aviptadil can be used for the research of pulmonary fibrosis, pulmonary arterial hypertension (PAH) and SARS-CoV-2 caused respiratory failure, et al [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Peptides. Alternative Names: Vasoactive Intestinal Peptide (human, rat, mouse, rabbit, canine, porcine). CAS No. 40077-57-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-P0012. | |
| Aviptadil acetate | Aviptadil acetate is an analog vasoactive intestinal polypeptide (VIP) with potent vasodilatory effects. Aviptadil acetate induces pulmonary vasodilation and inhibits vascular SMCs proliferation, platelet aggregation. Aviptadil acetate can be used for the research of pulmonary fibrosis, pulmonary arterial hypertension (PAH) and SARS-CoV-2 caused respiratory failure, et al [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Vasoactive Intestinal Peptide acetate salt (human, rat, mouse, rabbit, canine, porcine). CAS No. 1444827-29-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P0012A. | |
| Avitinib | Avitinib (Abivertinib) is a third-generation, irreversible and orally active selective EGFR inhibitor, with IC 50 values of 0.18 nM, 0.18 nM, 7.68 nM and against EGFR L858R , EGFR T790M and wild-type EGFR. Avitinib is also a BTK inhibitor that induces apoptosis and inhibits phosphorylation of BTK in mantle cell lymphoma. Avitinib shows anticancer effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Abivertinib; AC0010. CAS No. 1557267-42-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-19816. | |
| Avitinib | Avitinib (AC0010) is a third generation inhibitor of the EGFR (epidermal growth factor receptor) that was permitted parallel phase I clinical trials in the US. It is a pyrrolopyrimidine-based irreversible EGFR inhibitor that is mutation-selective with IC50 value of 0.18 nM against EGFR L858R/T790M double mutations. Upon oral administration, avitinib covalently binds to and inhibits the activity of mutant forms of EGFR. Uses: Tyrosine kinase inhibitors. Synonyms: AC0010. Grades: ≥98%. CAS No. 1557267-42-1. Molecular formula: C26H26FN7O2. Mole weight: 487.5. | |
| Avitinib maleate | Avitinib maleate, the maleate salt form of avitinib, is a pyrrolopyrimidine-based, irreversible epidermal growth factor receptor (EGFR) mutant-selective inhibitor (IC50 = 7.68 nM), with potential antineoplastic activity. Uses: Tyrosine kinase inhibitors. Synonyms: Avitinib maleate; AC0010MA; AC-0010MA; AC 0010MA; AC0010; AC-0010; AC 0010. CAS No. 1557268-88-8. Molecular formula: C30H30FN7O6. Mole weight: 603.6. | |
| Avitinib maleate | Avitinib (Abivertinib) maleate is a third-generation, irreversible and orally active selective EGFR inhibitor, with IC 50 values of 0.18 nM, 0.18 nM, 7.68 nM and against EGFR L858R , EGFR T790M and wild-type EGFR. Avitinib maleate is also a BTK inhibitor that induces apoptosis and inhibits phosphorylation of BTK in mantle cell lymphoma. Avitinib maleate shows anticancer effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Abivertinib maleate; AC0010 maleate. CAS No. 1557268-88-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19816A. | |
| Avitriptan | Avitriptan is an antimigraine drug of the triptan family which was never marketed. It acts as a 5-HT1B and 5-HT1D receptor agonist. Synonyms: 1-[3-[3-[4-(5-methoxypyrimidin-4-yl)piperazin-1-yl]propyl]-1H-indol-5-yl]-N-methyl-methanesulfonamide. Grades: > 95%. CAS No. 151140-96-4. Molecular formula: C22H30N6O3S. Mole weight: 458.59. | |
| Avitriptan fumarate | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Avizafone Dihydrobromide | Avizafone Dihydrobromide is a prodrug of Diazepam, which is a benzodiazepine used as an anti-anxiety and muscle relaxant, as well as to treat epilepsy. Synonyms: L-Lysyl-N-(2-benzoyl-4-chlorophenyl)-N-methyl-glycinamide Dihydrobromide; Prodiazepam Dihydrobromide; N-[3-(2-Benzoyl-4-chlorophenyl)-2-oxobutyl]-L-lysinamide Dihydrobromide. Grades: ≥95%. CAS No. 60067-15-4. Molecular formula: C22H29Br2ClN4O3. Mole weight: 592.75. | |
| Avizakimab | Avizakimab (BOS161721) is a humanized IgG1 monoclonal antibody that targets interleukin-21 [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BOS161721. CAS No. 2229685-51-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99451. | |
| AVL-292 | AVL-292, also known as CC-292, is an orally bioavailable, selective inhibitor of Bruton's agammaglobulinemia tyrosine kinase (BTK), with potential antineoplastic activity. Upon administration, AVL-292 targets and covalently binds to BTK, thereby preventing its activity. Uses: Protein kinase inhibitors. Synonyms: CC-292; CC292; CC 292; AVL292; AVL 292; spebrutinib. Grades: 98%. CAS No. 1202757-89-8. Molecular formula: C22H22FN5O3. Mole weight: 423.44. | |
| AVL-292 benzenesulfonate | AVL-292 benzenesulfonate is a covalent, highly selective, orally active small molecule inhibitor of Btk with IC50 value of 0.5 nM; >1400-fold selectivity over the other kinases assayed. Synonyms: Spebrutinib besylate; CC-292 besylate; AVL-292 benzenesulfonate; CC 292 besylate; AVL 292 benzenesulfonate; CC292 besylate; AVL292 benzenesulfonate. Grades: >98%. CAS No. 1360053-81-1. Molecular formula: C28H28FN5O6S. Mole weight: 581.62. | |
| AVN-101 hydrochloride | AVN-101 is an antagonist of the serotonin (5-HT) receptor subtypes 5-HT7, 5-HT2C, 5-HT2A, and 5-HT6 (Kis = 0.153, 1.17, 1.56, and 2.04 nM, respectively). It is also an antagonist of α2A-, α2B-, α2C-, α1B-, α1A-, and α1D-adrenergic receptors (Kis = 0.41, 1.77, 3.55, 9.4, 18.9, and 30.2 nM, respectively), as well as histamine H1 and H2 (Kis = 0.58 and 89 nM, respectively), but not H3, receptors. It is a multi-target drug candidate for the treatment of CNS disorders. Synonyms: 2,8-Dimethyl-5-phenethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole hydrochloride; AVN-101 HCl; 1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2,8-dimethyl-5-(2-phenylethyl)-, hydrochloride (1:1); 2,8-dimethyl-5-(2-phenylethyl)-1H,2H,3H,4H,5H-pyrido[4,3-b]indole hydrochloride; 2,3,4,5-tetrahydro-2,8-dimethyl-5-(2-phenylethyl)-1H-pyrido[4,3-b]indole, monohydrochloride. Grades: ≥95%. CAS No. 1061354-48-0. Molecular formula: C21H25ClN2. Mole weight: 340.90. | |
| AVN-101 hydrochloride | AVN-101 hydrochloride is a potent, brain-penetrant and orally active 5-HT7 receptor antagonist ( K i of 153 pM), with slightly lesser potency toward 5-HT6 , 5-HT2A , and 5HT-2C receptors ( K i values of 2.04 nM, 1.56 ?nM, and 1.17? nM, respectively). AVN-101 hydrochloride also exhibits a rather high affinity toward histamine H1 ( K i of 0.58 nM) and adrenergic α2A , α2B , and α2C (Ki= 0.41-3.6 nM) receptors. AVN-101 hydrochloride can be studied in such diseases as general anxiety disorders, depression, schizophrenia, and multiple sclerosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1061354-48-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117046A. | |
| AVN-211 | This active molecular is a Selective 5-HT6 Receptor antagonist, for the treatment of Alzheimer's Disease under development by by Avineuro Pharmaceuticals. AVN-211 shows good anxiolytic efficacy, low toxicity ,no side effects in vivo, an appropriate pharmacokinetic profile and good stability. AVN-211 significantly delayed or partially halted the progressive decline in memory function associated with AD and this efficacy makes it an interesting drug candidate for the treatment of neurodegenerative and psychiatric disorders. In Jul 2015, Avineuro Pharmaceuticals completed a phase II trial in Schizophrenia in USA and planed a trial for Alzheimer's disease in USA. In Aug 2015, Phase-II development was ongoing for Schizophrenia in USA. Uses: Alzheimer's disease;schizophrenia. Synonyms: AVN-211; AVN 211; AVN211; CD-008-0173. 5,7-dimethyl-2-(methylthio)-3-(phenylsulfonyl)pyrazolo[1,5-a]pyrimidine,CD-008-0173. Grades: 98%. CAS No. 1173103-84-8. Molecular formula: C15H15N3O2S2. Mole weight: 333.42. | |
| AVN-492 | AVN-492 is a novel potent and selective 5-HT6 receptor antagonist with Ki values of 91 pM and 170 nM for 5-HT6R and 5-HT2BR, respectively. Uses: Serotonin antagonists. Synonyms: AVN-492; AVN 492; AVN492. 3-(benzenesulfonyl)-2-N,6-N,6-N,5,7-pentamethylpyrazolo[1,5-a]pyrimidine-2,6-diamine. CAS No. 1220646-23-0. Molecular formula: C17H21N5O2S. Mole weight: 359.45. | |
| AVN-944 | AVN-944 (VX-944) is an orally available, synthetic small molecule with potential antineoplastic activity. AVN944 inhibits inosine monosphosphate dehydrogenase (IMPDH), an enzyme involved in the de novo synthesis of guanosine triphosphate (GTP), a purine molecule required for DNA and RNA synthesis. AVN944 appears to have a selective effect on cancer cells in that deprivation of GTP in normal cells results in a temporary slowing of cell growth only. Synonyms: code name: AVN 944; AVN944; VX-944; VX 944; VX944. Grades: 0.98. CAS No. 297730-17-7. Molecular formula: C25H27N5O5. Mole weight: 477.51. | |
| Avobenzone | Avobenzone, a dibenzoylmethane compound, is one of the most widely used filters in sunscreens for skin photoprotection in the UVA band. Avobenzone is an endocrine disruptor that directly binds to estrogen receptor β and acts as an estrogen agonist [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 70356-09-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0316. | |
| Avobenzone | Oil-soluble UVA filter. Ability to absorb ultraviolet light over a wider range of wavelengths than many other sunscreen agents. Absorption maximum of 357 nm. Uses: Sun care products, baby sun care products, daily sun protection, decorative cosmetics. Additional or Alternative Names: Butyl methoxydibenzoylmethane. Product Category: Heterocyclic Organic Compound. Appearance: Off-white to yellowish, crystalline powder, weak odor. CAS No. 70356-09-1. Molecular formula: C20H22O3. Mole weight: 310.4. Purity: 97-104%. Density: 1.079. Product ID: ACM70356091. Alfa Chemistry ISO 9001:2015 Certified. | |
| Avobenzone | Avobenzone is an oil soluble ingredient used in sunscreen products to absorb the full spectrum of UVA rays and a dibenzoylmethane derivative. Synonyms: Avobenzonum; Parsol 1789; Parsol1789; Parsol-1789; HSDB 7423; HSDB-7423; HSDB7423; 1,3-Propanedione, 1-[4-(1,1-dimethylethyl)phenyl]-3-(4-methoxyphenyl)-; 1-[4-(1,1-Dimethylethyl)phenyl]-3-(4-methoxyphenyl)-1,3-propanedione; 1-(4-Methoxyphenyl)-3-(4-tert-butylphenyl)propane-1,3-dione; 1-(4'-tert-Butylphenyl)-3-(4'-methoxyphenyl)propane-1,3-dione; 3-(4-Methoxyphenyl)-1-(4-tert-butylphenyl)-1,3-propanedione; 4-(1,1-Dimethylethyl)-4'-methoxydibenzoylmethane; 4-Methoxy-4'-tert-butyldibenzoylmethane; 4-tert-Butyl-4'-methoxydibenzoylmethane; Butylmethoxydibenzoylmethane; Escalol 517; Eusolex 9020; Milestab 1789; NeoHeliopan 357; Parsol 1789; Parsol A; Parsol RTM 1789; Photoplex; Solarom BMBM; Uvinul BMBM. Grades: >98%. CAS No. 70356-09-1. Molecular formula: C20H22O3. Mole weight: 310.39. | |
| Avobenzone | 1-(4-Methoxyphenyl)-3-(4-tert-butylphenyl)-1,3-propanedione, Butyl methoxydibenzoylmethane. CAS No. 70356-09-1. Product ID: 8-05179. Molecular formula: C20H22O3. Mole weight: 310.39. |  |
| Avobenzone | Avobenzone. Group: Biochemicals. Alternative Names: 1-[4-(1,1-Dimethylethyl)phenyl]-3-(4-methoxyphenyl)-1,3-propanedione; 1-(4-tert-Butylphenyl)-3-(4-methoxyphenyl)propane-1,3-dione; Butyl methoxydibenzoyl methane . Grades: Highly Purified. CAS No. 70356-09-1. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C20H22O3. US Biological Life Sciences. | Worldwide |
| Avobenzone | analytical standard. Group: Uv blockers. | |
| Avobenzone | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Avocado Extract | Avocado Extract. Applications: Used for health care products, dietary supplements, herb medicine and cosmetic industry. Group: Others. Synonyms: Avocado Extract; Persea americana L. Purity: 30% Total Phytosterol by UV. Appearance: Yellow Brown fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Fruit. Species: Persea americana L. Avocado Extract; Persea americana L.; plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-122. | |
| Avocado Oil | Avocado Oil. CAS No. 8024-32-6. VIGON Item # 507697. Categories: Speciality Ingredients Suppliers, Fragrances, Perfumers, Cosmetics. |  America & Internationally |
| Avocado Powder | Avocado powder takes avocado as raw material, adopts spray drying technology, low temperature physical grinding technology, instant grinding, to obtain edible high quality avocado powder. Product ID: CDF4-0226. Category: Flavour. Product Keywords: Flavor Enhancers; Avocado Powder; CDF4-0226; Flavour;. Grade: Food Grade. Color: White powder. Physical State: powder. Storage: Room Temperature. Applications: It is widely used in processing various avocado flavored foods and added to various nutritional foods. |  |
| Avoralstat | Avoralstat, also known as BCX-4161, is an oral plasma kallikrein (PKK) inhibitor and Bradykinin inhibitor, used to treat hereditary angioedema. Synonyms: 3-[2-[(4-carbamimidoylphenyl)carbamoyl]-4-ethenyl-5-methoxyphenyl]-6-(cyclopropylmethylcarbamoyl)pyridine-2-carboxylic acid; BCX-4161; BCX 4161; BCX4161; Avoralstat. CAS No. 918407-35-9. Molecular formula: C28H27N5O5. Mole weight: 513.54. | |
| Avosentan | Avosentan is a competitive antagonist of Endothelin-1 (ET-1) with a high selectivity for the ETA receptor. Avosentan may be a potential option in the treatment of glaucoma. Group: Biochemicals. Alternative Names: N-[6-Methoxy-5-(2-methoxyphenoxy)-2-(4-pyridinyl)-4-pyrimidinyl]-5-methyl-2-pyridinesulfonamide; Ro 67-0565; SPP 301. Grades: Highly Purified. CAS No. 290815-26-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Avosentan | Avosentan, also known as SPP301, R-639, and RO 67-0565, is a potent and selective endothelin receptor(ETA receptor) antagonist. Synonyms: N-[6-methoxy-5-(2-methoxyphenoxy)-2-pyridin-4-ylpyrimidin-4-yl]-5-methylpyridine-2-sulfonamide;Avosentan;290815-26-8;UNII-L94KSX715K;SPP301; SPP301; SPP301; RO 67-0565; RO-67-0565; RO67-0565; R-639; Avosentan. Grades: 95%. CAS No. 290815-26-8. Molecular formula: C23H21N5O5S. Mole weight: 479.51. | |
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