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| Product | Description | |
|---|---|---|
| AT 7519 mesylate | AT 7519 mesylate is a small-molecule inhibitor of CDK including CDK 1, 2, 4, 5, 6, and 9 in vitro and it induces apoptosis in multiple myeloma via GSK-3β activation and RNA polymerase II inhibition. Synonyms: AT 7519 mesylate; AT7519 mesylate; AT-7519 mesylate; AT-7519M; AT 7519M, AT7519M; 4-[(2,6-dichlorobenzoyl)amino]-N-piperidin-4-yl-1H-pyrazole-5-carboxamide methanesulfonic acid. Grade: 99%. CAS No. 902135-89-1. Molecular formula: C16H17Cl2N5O2.CH4O3S. Mole weight: 478.35. |  |
| AT7519 TFA | AT7519 (AT7519M) TFA as a potent inhibitor of CDKs , with IC 50 s of 210, 47, 100, 13, 170, and <10 nM for CDK1, CDK2, CDK4 to CDK6, and CDK9, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AT7519M TFA. CAS No. 1431697-85-6. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50940A. |  |
| AT7519 trifluoroacetate | AT7519 is an ATP competitive CDK inhibitor with a Ki value of 38 nM for CDK1. AT7519 is inactive against all non-CDK kinases with the exception of GSK3β (IC50 = 89 nM). AT7519 shows potent antiproliferative activity in a variety of human tumor cell lines with IC50 values ranging from 40 nM for MCF-7 to 940 nM for SW620 consistent with the inhibition of CDK1 and CDK2. AT7519 induces dose-dependent cytotoxicity in multiple myeloma (MM) cell lines with IC50 values ranging from 0.5 to 2 μM at 48 hours, with the most sensitive cell lines being MM.1S (0.5 μM) and U266 (0.5 μM) and the most resistant MM.1R (>2 μM). It does not induce cytotoxicity in peripheral blood mononuclear cells (PBMNC). AT7519 partially overcomes the proliferative advantage conferred by IL6 and IGF-1 as well as the protective effect of bone marrow stromal cells (BMSCs). AT7519 induces rapid dephosphorylation of RNA pol II CTD at serine 2 and serine 5 sites, and leads to the inhibition of transcription, partially contributing to AT7519 induced cytotoxicity of MM cells. AT7519 induces activation of GSK-3β by down-regulating GSK-3β phosphorylation, which also contributes to AT7519 induced apoptosis independent of the inhibition of transcription. A twice daily dosing of AT7519 (9.1 mg/kg) causes tumor regression of both early-stage and advanced-stage s.c. tumors in the HCT116 and HT29 colon cancer xenograft models. AT7519 tre | |
| AT7867 | AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively; little activity outside the AGC kinase family. Synonyms: AMG-706; AMG 706; AMG706; AT7867; AT 7867; AT-7867. Grade: >98%. CAS No. 857531-00-1. Molecular formula: C20H20ClN3. Mole weight: 337.85. | |
| AT7867 | AT7867 is a potent ATP-competitive inhibitor of Akt1 / Akt2 / Akt3 and p70S6K / PKA with IC 50 s of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 857531-00-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-12059. | |
| AT7867 dihydrochloride | AT7867 dihydrochloride is a potent ATP-competitive inhibitor of Akt1 / Akt2 / Akt3 and p70S6K / PKA with IC 50 s of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1431697-86-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12059A. | |
| AT7867 dihydrochloride | AT7867 also inhibits structurally related AGC kinases p70S6K and PKA with IC50 of 20 nM and 85 nM, respectively. AT7867 shows ATP-competitive activity to Akt2 with Ki of 18 nM. AT7867 exhibits antiproliferation in cell lines with PTEN or PIK3CA mutations and shows great potent to MES-SA, MDA-MB-468, MCF-7, HCT116 and HT29 with IC50 of 0.94 μM, 2.26 μM, 1.86 μM, 1.76 μM and 3.04 μM, respectively. AT7867 also suppresses the cell growth of U87MG, PC-3 and DU145 cells with IC50 of 8.22 μM, 10.37 μM and 11.86 μM, respectively. AT7867 suppresses Akt activity by inhibiting phosphorylation of GSK-3β in human tumor cells with IC50 of 2-4 μM. AT7867 also induces the phosphorylation of the following Akt direct substrates including proapoptotic transcription factors FKHR (FoxO1a), FKHRL1 (FoxO3a) and the downstream target S6RP in U87MG cells. AT7867 shows bioavailability of 44% in mice by p.o. route. AT7867 could increase the cleaved PARP in MES-SA xenografts at 20 mg/kg i.p. or 90 mg/kg p.o. AT7867 significantly inhibits the tumor growth in MES-SA xenografts or U87MG xenografts with T/C of 0.37 and 0.51, respectively. Synonyms: AT-7867 dihydrochloride; AT 7867 dihydrochloride. Grade: >98%. CAS No. 1431697-86-7. Molecular formula: C20H22Cl3N3. Mole weight: 410.77. | |
| AT791 | AT791 is a potent and orally bioavailable TLR7 and TLR9 inhibitor. AT791 inhibits TLR7 and 9 signaling in a variety of human and mouse cell types and inhibits DNA-TLR9 interaction in vitro[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1219962-49-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-124603. | |
| AT-9010 | AT-9010 is a potent inhibitor of NiRAN which is a function essential for viral replication. AT-9010 can inhibit SARS-CoV-2 replication. Synonyms: (2'R)-2'-Deoxy-2'-fluoro-2'-methylguanosine 5'-(tetrahydrogen triphosphate). Grade: >98%. CAS No. 1261253-79-5. Molecular formula: C11H17FN5O13P3. Mole weight: 539.20. | |
| AT-9010 tetrasodium | AT-9010 tetrasodium can inhibit SARS-CoV-2 replication. Synonyms: AT-9010. Grade: ≥98% by HPLC. CAS No. 1621884-18-1. Molecular formula: C11H13FN5Na4O13P3. Mole weight: 627.13. | |
| AT-9010 triethylamine | The active triphosphate metabolite AT-9010 can inhibit SARS-CoV-2 replication. Synonyms: UNII-IR49Q7E87C triethylamine. Grade: ≥98% (HPLC). CAS No. 2648089-95-4. Molecular formula: C35H77FN9O13P3. Mole weight: 943.96. | |
| At9283 | AT9283 is a multi-targeted kinase inhibitor with potent activity against Aurora A/B, JAK2/3, Abl (T315I) and Flt3 (IC50s ranging from 1 to 30 nM). AT9283 inhibits growth and survival of multiple solid tumors in vitro and in vivo. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-Cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea;1-Cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)ureaAT9283;AT9283, >=98%;N-cyclopropyl-N-[3-[5-(4-morpholinylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]Urea;Urea, N-cyclopropyl-N-[3-[6-(4-morpholinylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]-. Product Category: Inhibitors. CAS No. 896466-04-9. Molecular formula: C19H23N7O2. Mole weight: 381.438. Purity: 0.997. Density: 1.45. Product ID: ACM896466049. Alfa Chemistry ISO 9001:2015 Certified. |  |
| AT9283 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| AT9283 | AT9283 is a multi-targeted kinase inhibitor with potent activity against Aurora A/B , JAK2/3 , Abl (T315I) and Flt3 ( IC 50 s ranging from 1 to 30 nM). AT9283 inhibits growth and survival of multiple solid tumors in vitro and in vivo [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 896466-04-9. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50514. | |
| AT9283 | AT-9283 is a broad spectrum kinase inhibitor that potently inhibits Aurora A, Aurora B, JAK2, JAK3, and c-ABL (IC50= 3, 3, 1.2, 1.1, and 4 nM, respectively). It also potently (IC50 = <1 μM) inhibits serine/threonine kinases as well as receptor and non-receptor tyrosine kinases. Synonyms: AT9283; AT 9283; AT-9283. Grade:>98%. CAS No. 896466-04-9. Molecular formula: C19H23N7O2. Mole weight: 381.43. | |
| AT-9283 L-lactate | AT9283 is a multikinase inhibitor, is also a small-molecule inhibitor of several kinases with potential antineoplastic activity. AT9283 binds to and inhibits Aurora kinases A and B, JAK2 (Janus kinase 2) and the kinase BCR-ABL, which may result in the inhibition of cellular division and proliferation and the induction of apoptosis in tumor cells that overexpress these kinases. Synonyms: AT 9283; AT9283. CAS No. 896466-76-5. Molecular formula: C19H23N7O2. Mole weight: 471.52. | |
| Atabecestat | Atabecestat (JNJ-54861911) is a potent brain-penetrant and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, achieves robust and high CSF Aβ reduction. Atabecestat s tolerated and displays a sustained pharmacokinetic (PK) and pharmacodynamic (PD) characteristics. Atabecestat has the potential for Alzheimer's Disease treatment [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ-54861911. CAS No. 1200493-78-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-109052. | |
| Atacicept | Atacicept (TACI-Ig) is a is a recombinant fusion protein containing the extracellular, ligand-binding portion of the TACI receptor and the Fc portion of human IgG. Atacicept inhibits B cell stimulation by binding to B lymphocyte stimulator and a proliferation-inducing ligand. Atacicept can be used in research of B-cell autoimmune disease [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: TACI-Ig; TACI-Fc 5. CAS No. 845264-92-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99446. | |
| Ataciguat | Ataciguat. Group: Biochemicals. Alternative Names: 5-Chloro-2-[[ (5-chloro-2-thienyl) sulfonyl]amino]-N-[4- (4-morpholinylsulfonyl) phenyl]benzamide; HMR 1766. Grades: Highly Purified. CAS No. 254877-67-3. Pack Sizes: 100mg. Molecular Formula: C21H19Cl2N3O6S3. US Biological Life Sciences. |  Worldwide |
| Ataciguat | Ataciguat, formerly referred to as HMR-1766, a novel anthranilic acid derivative, is a potent guanylate cyclase activator. Ataciguat has potential to treat diseases associated with increased vascular tone combined with enhanced ROS production. Uses: Ataciguat, formerly referred to as hmr-1766, a novel anthranilic acid derivative, belongs to a new structural class of sgc activators capable of activating the oxidized form of sgc. ataciguat has been shown to improve endothelial function and to reduce p. Synonyms: HMR-1766; HMR 1766; HMR1766; Ataciguat; 5-Chloro-2-[[(5-chloro-2-thienyl)sulfonyl]amino]-N-[4-(4-morpholinylsulfonyl)phenyl]benzamide; Ataciguat; HMR 1766. Grade: >98%. CAS No. 254877-67-3. Molecular formula: C21H19Cl2N3O6S3. Mole weight: 576.5. | |
| Ataciguat | Ataciguat (HMR-1766) is a nitric oxide-independent soluble guanylate cyclase (sGC) activator. Ataciguat is able to activate the ferric heme-iron redox form of sGC that stimulate the production of cyclic GMP (cGMP). Ataciguat exhibits vasodilator effects[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HMR-1766. CAS No. 254877-67-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17500. | |
| ATAD2A (981-1108) human | recombinant, expressed in E. coli, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| ATAD2B (953-1080) human | recombinant, expressed in E. coli, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| At-AFP1 | At-AFP1 is an antimicrobial peptide produced by Arabidopsis thaliana (Mouse-ear cress). It has antifungal activity against Alternaria brassicola (IC50=10 μg/ml), Botrytis cinerea (IC50=3.90 μg/ml), Fusarium culmorum (IC50=3 μg/ml), Fusarium oxysporum f.sp. lycopersici (IC50=3 μg/ml), Pyricularia oryzae (IC50=0.25 μg/ml) and Verticiliium dahliae (IC50=1.50 μg/ml). Synonyms: Defensin-like protein 13; Protein LCR67; Lys-Leu-Cys-Glu-Arg-Pro-Ser-Gly-Thr-Trp-Ser-Gly-Val-Cys-Gly-Asn-Ser-Asn-Ala-Cys-Lys-Asn-Gln-Cys-Ile-Asn-Leu-Glu-Lys-Ala-Arg-His-Gly-Ser-Cys-Asn-Tyr-Val-Phe-Pro-Ala-His-Lys-Cys-Ile-Cys-Tyr-Phe-Pro-Cys (Disulfide bridge: Cys3-Cys50, Cys14-Cys35, Cys20-Cys44, Cys24-Cys46). Grade: >98%. | |
| Atagabalin | Atagabalin, also referred to PD-0200,390, is a gabamimetic agent developed as a treatment for insomnia but was discontinued following unsatisfactory trial results. Synonyms: 2-[(3S,4S)-1-(aminomethyl)-3,4-dimethylcyclopentyl]acetic acid; (1-aminomethyl-3,4-dimethylcyclopentyl)acetic acid; PD 0200390; PD-0200390; PD0200390. Grade: >98%. CAS No. 223445-75-8. Molecular formula: C10H19NO2. Mole weight: 185.267. | |
| Ataluren | Ataluren is an investigational new drug designed to enable the formation of a functioning protein in patients with genetic disorders due to a nonsense mutation. Ataluren is currently being investigated for use in patients with nonsense mutation Duchenne/Becker muscular dystrophy (nmDBMD) and cystic fibrosis (nmCF). Synonyms: PTC124; PTC-124; PTC 124. Grade: 0.98. CAS No. 775304-57-9. Molecular formula: C15H9FN2O3. Mole weight: 284.246. | |
| Ataluren | Ataluren (PTC124) is an orally available CFTR-G542X nonsense allele inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PTC124. CAS No. 775304-57-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-14832. | |
| Ataluren-[d4] | Ataluren-[d4] is a labelled Ataluren. Ataluren is a medication used for the treatment of Duchenne muscular dystrophynonsense caused by nonsense mutation (nmDMD). Synonyms: 3-(5-(2-Fluorophenyl-3,4,5,6-d4)-1,2,4-oxadiazol-3-yl)benzoic acid; Ataluren-D4; 3-[5-(6-Fluorophenyl-2,3,4,5-d4)-1,2,4-oxadiazol-3-yl]benzoic acid; PTC124-d4. Grade: >95%. CAS No. 1922064-61-6. Molecular formula: C15H5D4FN2O3. Mole weight: 288.27. | |
| Atamestane | Atamestane is a synthetic steroidal substance with antineoplastic activity. Atamestane binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens. Uses: Enzyme inhibitors. Synonyms: Atamestanum; Atamestano; Biomed-777; Biomed 777; Biomed777; CCRIS 6528; CCRIS6528; CCRIS-6528; SH-489; SH 489; SH489. CAS No. 96301-34-7. Molecular formula: C20H26O2. Mole weight: 298.43. | |
| Ataquimast | Ataquimast is used in curing advanced receptor-positive breast cancer. Ataquimast inhibits IL-5 secretion along with that of TNF-a, IL-4 and GM-CSF from human cells. Synonyms: 1-Ethyl-3-(methylamino) 2(1H)-quinoxalinone. CAS No. 182316-31-0. Molecular formula: C11H13N3O. Mole weight: 203.24. | |
| ATAT1 human | recombinant, expressed in E. coli, ?55% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| Ataxin3 active human | recombinant, expressed in E. coli, ?59% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| Atazanavir | 100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C38H52N6O7. CAS No. 198904-31-3. Prepack ID 89984074-100mg. Molecular Weight 704.86. See USA prepack pricing. |  |
| Atazanavir | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopychiral moleculesenzyme activators, inhibitors & substrates. Alternative Names: BMS 232632, 1,14-Dimethyl (3S,8S,9S,12S)-3,12-bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-2,5,6,10,13-pentaazatetradecanedioate, Atazanavir, CGP 73547,2,5,6,10,13-Pentaazatetradecanedioic acid, 3,12-bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-, 1,14-dimethyl ester, (3S,8S,9S,12S)-, 2,5,6,10,13-Pentaazatetradecanedioic acid, 3,12-bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-, dimethyl ester, (3S,8S,9S,12S)- (9CI), 2,5,6,10,13-Pentaazatetradecanedioic acid, 3,12-bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-, dimethyl ester, [3S-(3R*,8R*,9R*,12R*)]-, Reyataz. | |
| Atazanavir | Atazanavir is a novel and potent azapeptide protease inhibitor that specifically inhibits the human immunodeficiency virus type 1 (HIV-1) protease enzyme with inhibition constant Ki of 66 nmol/L and also inhibits the viral replication of HIV-1 with 50% effective concentration EC50 ranging from 2.6 to 5.3 nmol/L. Atazanavir binds to HIV-1 protease preventing the cleavage of gag and gag-pol polyproteins, which results in the formation of immature virions in HIV-1-infected cells. Atazanavir has a different C-2 symmetric chemical structure and a generally greater antiretroviral potency in various HIV strains compared to other protease inhibitors, including indinavir, nelfinavir, ritonavir, saquinavir and amprenavir. Synonyms: Atazanavir ; Reyataz ; Atazanavir sulfate ; CGP75136 ; CGP75176 ; CGP75355 ; BMS232632 ; CGP 73547 ; CGP 75136 ; CGP 75176 ; CGP 75355 ; CGP-73547 ; CGP-75136 ; CGP-75176 ; CGP-75355 ; BMS 232632 ; BMS-232632 ; BMS-232632-05 ; C413408. Grade: 0.98. CAS No. 198904-31-3. Molecular formula: C38H52N6O7. Mole weight: 704.869. | |
| Atazanavir | Atazanavir (BMS-232632) is a highly selective and orally active HIV-1 protease inhibitor. Atazanavir is a substrate and inhibitor of CYP3A4 , and an inhibitor of P-glycoprotein (P-gp). Atazanavir is also a SARS-CoV 3CL pro inhibitor with an IC 50 of 3.49 μM. Atazanavir inhibits cardiac fibrosis, hyperlipidemia and induces malignant glioma death [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Natural products. Alternative Names: BMS-232632. CAS No. 198904-31-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17367. | |
| Atazanavir | Atazanavir is a HIV-1 protease inhibitor, used in the anti-retroviral therapy of adult and sometimes paediatric patients infected with HIV. In in vitro studies with human pulmonary epithelial cells, atazanavir has been studied as a potential inhibitor of SARS-CoV-2 Mpro protease, with the aim of halting viral replication. Group: Biochemicals. Alternative Names: 3, 12-Bis (1, 1-dimethylethyl) -8-hydroxy-4, 11-dioxo-9- (phenylmethyl) -6-[[4- (2-pyridinyl) phenyl]methyl]-dimethyl ester; (3S,8S, 9S, 12S) -2, 5, 6, 13-Pentaazatetradecane dioic acid; BMS-232632. Grades: Highly Purified. CAS No. 198904-31-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C??H??N?O?, Molecular Weight: 704.86. US Biological Life Sciences. | Worldwide |
| Atazanavir Bisulfate Salt | Atazanavir is a novel azapeptide HIV protease inhibitor (PI). Antiviral. Group: Biochemicals. Alternative Names: 3, 12-Bis (1, 1-dimethylethyl) -8-hydroxy-4, 11-dioxo-9- (phenylmethyl) -6-[[4- (2-pyridinyl) phenyl]methyl]-dimethyl Ester, (3S,8S, 9S, 12S) -2, 5, 6, 13-Pentaazatetradecane dioic Acid; BMS-232632; CGP-73547; Reyataz. Grades: Highly Purified. CAS No. 229975-97-7. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Atazanavir-d5, Bisulfate Salt (3, 12-Bis (1, 1-dimethylethyl) -8-hydroxy-4, 11-dioxo-9- (phenylmethyl) -6-[[4- (2-pyridinyl) phenyl]methyl]-dimethyl Ester, (3S,8S, 9S, 12S) -2, 5, 6, 13-Pentaazatetradecane dioic acid-d5, BMS 232632-d5, CGP 73547-d5, Reyataz-d5) | Atazanavir is a novel azapeptide protease inhibitor (PI). Group: Biochemicals. Alternative Names: 3, 12-Bis (1, 1-dimethylethyl) -8-hydroxy-4, 11-dioxo-9- (phenylmethyl) -6-[[4- (2-pyridinyl) phenyl]methyl]-dimethyl Ester, (3S,8S, 9S, 12S) -2, 5, 6, 13-Pentaazatetradecane dioic acid-d5; BMS 232632-d5; CGP 73547-d5; Reyataz-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Atazanavir-d6 | Atazanavir-d6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1092540-50-5. Molecular formula: C38H46D6N6O7. Mole weight: 710.91. Catalog: APB1092540505. | |
| Atazanavir-[d6] | Atazanavir-[d6] is the labelled analogue of Atazanavir. Atazanavir is a novel and potent azapeptide protease inhibitor that specifically inhibits the human immunodeficiency virus type 1 (HIV-1) protease enzyme with inhibition constant Ki of 66 nmol/L and also inhibits the viral replication of HIV-1 with 50% effective concentration EC50 ranging from 2.6 to 5.3 nmol/L. Atazanavir binds to HIV-1 protease preventing the cleavage of gag and gag-pol polyproteins, which results in the formation of immature virions in HIV-1-infected cells. Atazanavir has a different C-2 symmetric chemical structure and a generally greater antiretroviral potency in various HIV strains compared to other protease inhibitors, including indinavir, nelfinavir, ritonavir, saquinavir and amprenavir. Synonyms: Atazanavir D6; (3S,8S,9S,12S)-12-Bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-2,5,6,10,13-Pentaazatetradecanedioic Acid 14-di(methyl-d3) Ester. Grade: ≥98%; ≥99% atom D. CAS No. 1092540-50-5. Molecular formula: C38H46D6N6O7. Mole weight: 710.89. | |
| Atazanavir Di-tert-butyl Analog | An impurity of Atazanavir. Synonyms: Des-N-(methoxycarbonyl)-L-tert-leucine Bis-Boc Atazanavir. Grade: > 95%. CAS No. 198904-86-8. Molecular formula: C32H42N4O5. Mole weight: 562.72. | |
| Atazanavir EP Impurity F (Atazanavir R,S,S,S-Diastereomer) | Atazanavir EP Impurity F (Atazanavir R,S,S,S-Diastereomer). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl ((5S,8S,9S,14R)-8-benzyl-5-(tert-butyl)-9-hydroxy-15,15-dimethyl-3,6,13-trioxo-11-(4-(pyridin-2-yl)benzyl)-2-oxa-4,7,11,12-tetraazahexadecan-14-yl)carbamate. CAS No. 1332981-14-2. Molecular formula: C38H52N6O7. Mole weight: 704.86. Catalog: APB1332981142. | |
| Atazanavir EP Impurity G (Atazanavir S,S,S,R-Diastereomer) | Atazanavir EP Impurity G (Atazanavir S,S,S,R-Diastereomer). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl ((5R,8S,9S,14S)-8-benzyl-5-(tert-butyl)-9-hydroxy-15,15-dimethyl-3,6,13-trioxo-11-(4-(pyridin-2-yl)benzyl)-2-oxa-4,7,11,12-tetraazahexadecan-14-yl)carbamate. CAS No. 1332981-16-4. Molecular formula: C38H52N6O7. Mole weight: 704.86. Catalog: APB1332981164. | |
| Atazanavir Hydrazine Analog Trihydrochloride | An intermediate for the synthesis of Atazanavir and the preparation of some peptide analogs. Synonyms: Des-N-(methoxycarbonyl)-L-tert-leucine Atazanavir Trihydrochloride. Grade: > 95%. CAS No. 198904-87-9. Molecular formula: C22H26N4O. 3 HCl. Mole weight: 362.48 3 36.46. | |
| Atazanavir Impurity 1 | An epimeric impurity of Atazanavir. Synonyms: (3S,8R,9S,12S)-3,12-Bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-,2,5,6,10,13-pentaazatetradecanedioic Acid 1,14-Dimethyl Ester. Grade: > 95%. CAS No. 1292296-09-3. Molecular formula: C38H52N6O7. Mole weight: 704.87. | |
| Atazanavir Impurity 20 | Atazanavir Impurity 20. Uses: For analytical and research use. Group: Impurity standards. CAS No. 102123-74-0. Molecular formula: C15H20ClNO3. Mole weight: 297.78. Catalog: APB102123740. | |
| Atazanavir Impurity 5 | An impurity of Atazanavir. Atazanavir is a novel and potent azapeptide protease inhibitor that specifically inhibits the human immunodeficiency virus type 1 (HIV-1) protease enzyme. Synonyms: 4-O-[4,6-O-[4-(pyridin-2-yl)benzylidene]-β-D-galactopyranosyl]-β-D-glucopyranoside. Grade: >95%. Molecular formula: C24H29NO11. Mole weight: 507.50. | |
| Atazanavir Impurity 6 | Atazanavir Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1006868-81-0. Molecular formula: C32H42N4O5. Mole weight: 562.71. Catalog: APB1006868810. | |
| Atazanavir Impurity 8 | Atazanavir Impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1028634-76-5. Molecular formula: C36H50N6O5. Mole weight: 646.83. Catalog: APB1028634765. | |
| Atazanavir Impurity B | An impurity of Atazanavir. Synonyms: 1-Boc-2-[4-(2-pyridinyl)benzylidene]hydrazine. Grade: > 95%. CAS No. 198904-85-7. Molecular formula: C17H21N3O2. Mole weight: 299.38. | |
| Atazanavir Impurity C | An impurity of Atazanavir. Synonyms: (2R,3S)-3-(tert-Boc)amino-1,2-epoxy-4-phenylbutane; N-[(1S)-1-[(2R)-2-Oxiranyl]-2-phenylethyl]-carbamic Acid 1,1-Dimethylethyl Ester; (2R,3S)-(+)-3-tert-Butoxycarbonylamino-1,2-epoxy-4-phenylbutane; [(1S)-1-((2R)-Oxiranyl)-2-phenylethyl]carbamic Acid tert-Butyl Ester. Grade: > 95%. CAS No. 98760-08-8. Molecular formula: C15H21NO3. Mole weight: 263.34. | |
| Atazanavir related compound A | An impurity of Atazanavir. Synonyms: N-(Methoxycarbonyl)-L-tert-leucine. Grade: > 95%. CAS No. 162537-11-3. Molecular formula: C8H15NO4. Mole weight: 189.21. | |
| Atazanavir Related Compound A | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Atazanavir R,S,S,R-Diastereomer | An impurity of Atazanavir. Synonyms: (3R,8S,9S,12R)-Atazanavir. Grade: > 95%. CAS No. 1292296-11-7. Molecular formula: C38H52N6O7. Mole weight: 704.87. | |
| Atazanavir R,S,S,S-diastereomer | An impurity of Atazanavir. Synonyms: (3R,8S,9S,12S)-Atazanavir. Grade: > 95%. CAS No. 1332981-14-2. Molecular formula: C38H52N6O7. Mole weight: 704.87. | |
| Atazanavir S,S,R,S-Diastereomer | An impurity of Atazanavir. Synonyms: (3R,8R,9S,12R)-Atazanavir. Grade: > 95%. CAS No. 1292296-10-6. Molecular formula: C38H52N6O7. Mole weight: 704.87. | |
| Atazanavir S,S,S,R-diastereomer | An impurity of Atazanavir. Synonyms: (3S,8S,9S,12R)-Atazanavir. Grade: > 95%. CAS No. 1332981-16-4. Molecular formula: C38H52N6O7. Mole weight: 704.87. | |
| Atazanavir sulfate | 100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C38H52N6O7 · H2SO4. CAS No. 229975-97-7. Prepack ID 24906497-100mg. Molecular Weight 802.93. See USA prepack pricing. | |
| Atazanavir sulfate | Atazanavir (BMS-232632) sulfate is a highly selective and orally active HIV-1 protease inhibitor. Atazanavir sulfate is a substrate and inhibitor of CYP3A4 , and an inhibitor of P-glycoprotein (P-gp). Atazanavir sulfate is also a SARS-CoV 3CL pro inhibitor with an IC 50 of 3.49 μM. Atazanavir sulfate inhibits cardiac fibrosis, hyperlipidemia and induces malignant glioma death [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Natural products. Alternative Names: BMS-232632 sulfate. CAS No. 229975-97-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17367A. | |
| Atazanavir sulfate | Residue on Ignition: Group: Biochemicals. Alternative Names: Methyl N- [ (2S) -1- [ [ (2S, 3S) -3-hydroxy-4- [ [ [ (2S) -2- (methoxycarbonylamino) -3, 3-dimethylbutanoyl] amino] - [ (4-pyridin-2-ylphenyl) methyl] amino] -1-phenylbutan-2-yl] amino] -3, 3-dimethyl-1-oxobutan-2-yl] carbamate sulfate. Grades: Highly Purified. CAS No. 229975-97-7. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. US Biological Life Sciences. | Worldwide |
| Atazanavir Sulfate | Atazanavir is a HIV protease inhibitor with Ki of 2.66 nM. It is an antiretroviral drug of the protease inhibitor (PI) class. Like other antiretrovirals, it is used to treat infection of human immunodeficiency virus. Uses: Hiv protease inhibitors. Synonyms: BMS-232632; BMS 232632; BMS232632; Reyataz. Grade: >98%. CAS No. 229975-97-7. Molecular formula: C38H52N6O7.H2SO4. Mole weight: 802.93. | |
| Atazanavir Sulphate | 3S,8S,9S,12S)-3,12-Bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl] methyl]-2,5,6,10,13-pentaazatetradecanedioic acid dimethyl ester, sulfate (1:1). CAS No. 198904-31-3. Product ID: 8-04390. Molecular formula: C38H52N6O7 H2SO4. Mole weight: 802.9. |  |
| Atazanavir System Suitability Mixture | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| ATB107 hydrochloride | ATB107 hydrochloride is a hydrochloride form of ATB107 that inhibits indole-3-glycerol phosphate synthase (IGPS) with a KD of 3 μM. Grade: >98.0%. Molecular formula: C21H29ClN8. Mole weight: 428.96. | |
| ATB 346 | ATB-346 is a novel hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity. CAS No. 1226895-20-0. Molecular formula: C21H19NO3S. Mole weight: 365.447. | |
| ATBTA-Eu3+, 90% | ATBTA-Eu3+, 90%. Group: other glass and ceramic materials. CAS No. 601494-52-4. Product ID: sodium; 2-[[6-[4-[4- (4-aminophenyl) phenyl]-6-[6-[[bis (carboxylatomethyl) amino]methyl]pyridin-2-yl]pyridin-2-yl]pyridin-2-yl]methyl- (carboxylatomethyl) amino]acetate; europium(3+). Molecular formula: 861.6g/mol. Mole weight: C37H30EuN6NaO8. C1=CC (=NC (=C1)C2=CC (=CC (=N2)C3=CC=CC (=N3)CN (CC (=O)[O-])CC (=O)[O-])C4=CC=C (C=C4)C5=CC=C (C=C5)N)CN (CC (=O)[O-])CC (=O)[O-]. [Na+]. [Eu+3]. InChI=1S/C37H34N6O8. Eu. Na/c38-27-13-11-24 (12-14-27)23-7-9-25 (10-8-23)26-15-32 (30-5-1-3-28 (39-30)17-42 (19-34 (44)45)20-35 (46)47)41-33 (16-26)31-6-2-4-29 (40-31)18-43 (21-36 (48)49)22-37 (50)51; ; /h1-16H, 17-22, 38H2, (H, 44, 45) (H, 46, 47) (H, 48, 49) (H, 50, 51); ; /q; +3; +1/p-4. WPJHPWPASHGOEZ-UHFFFAOYSA-J. |  |
| ATC 0065 | ATC 0065. Group: Biochemicals. Grades: Purified. CAS No. 510732-84-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| ATC0175 | ATC0175 is a potent, selective and orally active melanin-concentrating hormone 1 recepter antagonist with IC 50 s of 13.5, >10000 nM for MCH1R, MCH2R, respectively. ATC0175 shows antidepressant effects and anxiolytic effects in animal models. ATC0175 has the potential for the research of depression and/or anxiety disorders [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 510733-97-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107624. | |
| ATC 0175 hydrochloride | ATC 0175 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 510733-97-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
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