A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the suppliers website for prices or more information.
| Product | Description | |
|---|---|---|
| Autophagy Inhibitor IV, Cpd18 (3-methyl-6-(3-methylpiperidin-1-yl)-3H-purine, 3-MA analog, Cpd 18) | A cell-permeable 3-methyladenine (3-MA) derivative that acts as an autophagy inhibitor via the inhibition of class III PI3K, and without touching class I PI3K. Shown to block 80% of starvation-induced autophagy at 1 mM (IC50 = 0.67mM, compared with 3-MA at 6 mM). Displays much better solubility than 3-MA (5 times more soluble in water and 30 times more soluble in DMSO). Also found to reduce cell viability by 55% at 1 mM at 12 hours compared with 72% reduction for 3-MA at 10mM. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| Autophinib | Autophinib is a novel potent autophagy inhibitor, which can inhibit autophagy induced by starvation or rapamycin with IC50 values of 0.04 μM and 0.09 μM, respectively. Synonyms: 6-chloro-N-(5-methyl-1H-pyrazol-3-yl)-2-(4-nitrophenoxy)pyrimidin-4-amine. CAS No. 1644443-47-9. Molecular formula: C14H11ClN6O3. Mole weight: 346.73. |  |
| Autotaxin Inhibitor III, PF-8380 (Atx Inhibitor III, PF-8380, 6-(3-(Piperazin-1-yl)propanoyl)-benzo[d]oxazol-2(3H)-one) | An orally bioavailable piperazinyl benzoxazolone compound that acts as a substrate competitive and tight-binding inhibitor of autotaxin activity {IC50=2.8 and 1.7nM for recombinant human enzyme-b isoform employing FS-3 and LPC (lysophosphatidyl choline) as substrates, respectively; 1.16 and 1.15nM for rat/murine enzyme-FS-3 and fetal fibroblast cell-LPC; 101nM for human whole blood}. Displays desirable pharmacokinetics properties and efficiently blocks inflammation-induced LPA (lysophosphatidic acid) production both in plasma and at the site of inflammation by 95% in rat adjuvant-induced arthritis model (30mg/kg, p.o.).CAS No:1144035-53-9. Group: Biochemicals. Grades: Highly Purified. CAS No. 1144035-53-9. Pack Sizes: 10mg. Molecular Formula: C??H??Cl?N?O?. US Biological Life Sciences. | Worldwide |
| Autotaxin Inhibitor I, S32826 - CAS 1103672-43-0 | The Autotaxin Inhibitor I, S32826, also referenced under CAS 1103672-43-0, controls the biological activity of Autotaxin. Group: Fluorescence/luminescence spectroscopy. |  |
| Autotaxin Inhibitor IV, HA155 | The Autotaxin Inhibitor IV, HA155 controls the biological activity of Autotaxin. This small molecule/inhibitor is primarily used for Cell Structure applications. Group: Fluorescence/luminescence spectroscopy. | |
| AUY954 | NVP-AUY954 is an orally-available, benzothiazole-based, monoselective agonist of the sphingosine-1-phosphate receptor 1 (S1P1) intended for the treatment of human autoimmune mediated inflammatory neuropathies. NVP-AUY954 efficacy has been correlated with an accumulation of plasmacytoid dendritic cells (pDC), which may have therapeutic value in the treatment of multiple sclerosis. Uses: Sphingosine 1 phosphate receptor modulators. Synonyms: AUY954; AUY-954 free base; 820240-77-5; CHEMBL4579553; 820240-77-5 (free base); 3-[[2-[4-phenyl-3-(trifluoromethyl)phenyl]-1-benzothiophen-5-yl]methylamino]propanoic acid; 3-(((2-(2-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)benzo[b]thiophen-5-yl)methyl)amino)propanoic acid; N-[[2-[2-(trifluoromethyl)[1,1'-biphenyl]-4-yl]benzo[b]thien-5-yl]methyl]-beta-alanine; AUY 954; GTPL2925; SCHEMBL2237377; BCP33492; BDBM50507187; AKOS040750638; NVP-AUY954; AUY-954; AUY 954; Q27074628; 3-{[2-(2-trifluoromethyl-biphenyl-4-yl)benzo[b]thiophen-5-ylmethyl]amino}propionic acid. Grades: ≥98%. CAS No. 820240-77-5. Molecular formula: C25H20F3NO2S. Mole weight: 455.5. | |
| AV023 | AV023 is a potent inhibitor of ANKRD22. AV023 promotes the expansion of gastrointestinal mucosal epithelial stem cells and indirectly activates the Wnt classical pathway, which helps the recovery of damaged gastrointestinal mucosal tissues in the body (extracted from patent CN111205231B) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1107710-62-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145686. |  |
| AV123 | AV123 (compound 12) is a non-cytotoxic RIPK1 inhibitor ( IC 50 =12.12 μM). AV123 blocks the TNF-α-induced necroptotic ( EC 50 =1.7 μM) but not the apoptotic cell death. AV123 can be used in the study of necrotic chronic conditions such as ischemia-reperfusion injury of the brain, heart and kidney, inflammatory diseases, neurodegenerative diseases and infectious diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 233605-81-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-151369. | |
| AV-412 | AV-412 is a second-generation, orally bioavailable dual kinase inhibitor with potential antineoplastic activity. EGFR/HER2 inhibitor AV-412 binds to and inhibits the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2), which may suppress tumor growth and angiogenesis, and tumor regression in EGFR/HER2-expressing tumors. This agent may be active against EGFR/HER2-expressing tumor cells that are resistant to first-generation kinase inhibitors. EGFR and HER2 are receptor tyrosine kinases that play major roles in tumor cell proliferation and tumor vascularization. Synonyms: AV 412; AV412; N-[4-(3-chloro-4-fluoroanilino)-7-[3-methyl-3-(4-methylpiperazin-1-yl)but-1-ynyl]quinazolin-6-yl]prop-2-enamide. CAS No. 451492-95-8. Molecular formula: C27H28ClFN6O. Mole weight: 507.01. | |
| AV-412 Tosylate | AV-412 is a dual EGFR/ErbB2 kinase inhibitor. It completely inhibits the tumor growth of both H1650 and H1975 xenografts in nude mice. It is proved that AV-412 suppresses tumor growth via the inhibition of EGFR. Besides that, AV-412 also shows antitumor effects against various tumor models expressing EGFR, ErbB2 or both receptors, such as breast cancer KPL-4, prostate cancer DU145 and lung cancer LC-376. Uses: Antineoplastic agents. Synonyms: N-(4-((3-chloro-4-fluorophenyl)amino)-7-(3-methyl-3-(4-methylpiperazin-1-yl)but-1-yn-1-yl)quinazolin-6-yl)acrylamide bis(4-methylbenzenesulfonate); MP-412; MP 412; MP412; AV-412; AV 412; AV412; AV-412 tosylate. Grades: >98%. CAS No. 451493-31-5. Molecular formula: C41H44ClFN6O7S2. Mole weight: 851.41. | |
| AV5124 | AV5124, a prodrug of AV5116, is an orally active influenza virus cap-dependent endonuclease (CEN) endonuclease inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2417851-93-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-164927. | |
| Avacopan | Avacopan (CCX168) is a potent, selective and orally available complement 5a receptor ( C5aR ) inhibitor with an IC 50 of 0.1 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CCX168. CAS No. 1346623-17-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17627. | |
| Avadomide | Avadomide is an orally active cereblon modulator. Avadomide modulates cereblon E3 ligase activity, inhibits NF-κB pathway, arrests the cell cycle at G1 phase, and thus induces apoptosis in cancer cell PDAC. Avadomide exhibits potent antitumor and immunomodulatory activities [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CC 122. CAS No. 1015474-32-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100507. | |
| Avagacestat | Avagacestat (BMS-708163) is a potent inhibitor of γ-secretase , with IC 50 s of 0.27 nM and 0.30 nM for Aβ42 and Aβ40 inhibition; Avagacestat (BMS-708163) also inhibits NICD (Notch IntraCellular Domain) with IC 50 of 0.84 nM and shows weak inhibition of CYP2C19, with IC 50 of 20 μM. Avagacestat can be used for Alzheimer disease research. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-708163. CAS No. 1146699-66-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50845. | |
| Avagacestat | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Avagacestat | BMS-708163 is a potent and orally bioavailable inhibitor of γ-secretase that more potently inhibits the cleavage of APP (IC50 = 0.30 nM) to Aβ40 than signaling through Notch (IC50s = 58 nM). Uses: Gamma secretase inhibitors and modulators. Synonyms: Avagacestat; BMS 708163; (2R)-2-[(4-chlorophenyl)sulfonyl-[[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl]amino]-5,5,5-trifluoropentanamide. Grades: >98%. CAS No. 1146699-66-2. Molecular formula: C20H17ClF4N4O4S. Mole weight: 520.89. | |
| Avanafil | Avanafil (TA-1790) is a potent and selective phosphodiesterase-5 (PDE-5) inhibitor with IC 50 values of 5.2 nM, 630 nM, 5700 nM, 6200 nM, 12000 nM, 27000 nM, 51000 nM and 53000 nM for PDE-5, PDE-6, PDE-4, PDE-10, PDE-8, PDE-7, PDE-2 and PDE-1, respectively. Avanafil activates NO/cGMP/PKG signaling-pathway to decrease loss in BMD, bone atrophy, and oxidative stress. Avanafil inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. Avanafil can be used for the research of erectile dysfunction and osteoporosis [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: TA1790. CAS No. 330784-47-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-18252. | |
| Avanafil | A phosphodiesterase. Group: Biochemicals. Alternative Names: (S) -2- (2-Hydroxymethyl-1-pyrrolidinyl) -4- (3-chloro-4-methoxybenzylamino) -5-[ (2-pyrimidinylmethyl) carbamoyl]pyrimidine; 4-[[ (3-Chloro-4-methoxyphenyl) methyl]amino]-2-[ (2S) -2- (hydroxymethyl) -1-pyrrolidinyl]-N- (2-pyrimidinylmethyl) -5-pyrimidinecarboxamide; TA 1790. Grades: Highly Purified. CAS No. 330784-47-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Avanafil Impurity 13 | Avanafil Impurity 13 is an impurity of Avanafil, a medication prescribed for treating erectile dysfunction. Synonyms: 1,4,5,6-tetrahydropyrimidin-2-ylmethanamine; Avanafil Related Compound 1. Grades: > 95%. CAS No. 759408-08-7. Molecular formula: C5H11N3. Mole weight: 113.16. | |
| Avanafil Intermediates | Avanafil Intermediates. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1246834-64-9. Molecular formula: C7H11N3O2. Mole weight: 169.18. Catalog: APB1246834649. | |
| Avanafil metabolite M4 | Avanafil metabolite M4 is a major active metabolite of the phosphodiesterase 5 (PDE5) inhibitor avanafil. Avanafil is metabolized by the cytochrome P450 (CYP450) isoforms CYP3A4 and CYP2C to the major metabolites avanafil metabolite M4 and avanafil metabolite M16, as well as minor metabolites. Avanafil metabolite M4 inhibits PDE5 with 18% of the potency of avanafil. Grades: ≥98%. Molecular formula: C23H26ClN7O4. Mole weight: 499.95. | |
| Avanafil Related Compound 1 | Synonyms: 4-(3-chloro-4-MethoxybenzylaMino)-5-ethoxycarbonyl-2-MethylsulfinylpyriMidine; Ethyl 4-((3-chloro-4-Methoxybenzyl)aMino)-2-(Methylsulfinyl)pyriMidine-5-carboxylate. Grades: > 95%. CAS No. 330785-82-5. Molecular formula: C16H18ClN3O4S. Mole weight: 383.86. | |
| Avapritinib | Avapritinib (BLU-285) is a highly potent, selective, and orally active KIT and PDGFRA activation loop mutant kinases inhibitor with IC 50 s of 0.27 and 0.24 nM for KIT D816V and PDGFRA D842V , respectively. Avapritinib (BLU-285) binds the active conformation of the kinase and shows antitumor activity. Avapritinib (BLU-285) attenuates the transport function of both ABCB1 and ABCG2 [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BLU-285. CAS No. 1703793-34-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101561. | |
| Avapritinib | BLU-285 is a potent and selective inhibitor of exon 17 mutant KIT (IC50 = 0.27 nM for KIT D816V). BLU-285 showed dose-dependent, robust anti-tumor efficacy in a TKI-resistant KIT exon 11/17 mutant GIST PDX model through inhibition of tumor growth, proliferation, KIT signaling and induction of apoptosis. Synonyms: (1S)-1-(4-fluorophenyl)-1-[2-[4-[6-(1-methylpyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl]piperazin-1-yl]pyrimidin-5-yl]ethanamine; BLU-285; BLU 285; BLU285; UNII-513P80B4YJ; SCHEMBL16652297. CAS No. 1703793-34-3. Molecular formula: C26H27FN10. Mole weight: 498.56. | |
| Avarofloxacin hydrochloride | Avarofloxacin hydrochloride is an antibacterial drug agent. Uses: Avarofloxacin hydrochloride is an antibacterial drug agent. Synonyms: Avarofloxacin HCl;JNJ-Q2 hydrochloride;7-[(3E)-3-(2-amino-1-fluoroethylidene)piperidin-1-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxoquinoline-3-carboxylic acid hydrochloride;JNJ-32729463 hydrochloride;JNJ 32729463 hydrochloride. Grades: >98 %. CAS No. 1001162-01-1. Molecular formula: C21H24ClF2N3O4. Mole weight: 455.89. | |
| Avarol | Antibacterial against selected Gram-positive strains, antifungal. Anticancer compound. Antileukemic. Antimitotic agent. Antiviral compound. Inhibits HIV activity. Anti-inflammatory. Synovial phospholipase A2, cyclooxygenase and lipoxygenase inhibitor. Modulator of superoxide dismutase and glutathione peroxidase. Platelet aggregation inhibitor. Anti-psoriatic, mediated by inhibition of TNF-alpha generation and NF-kappaB activation. Group: Biochemicals. Alternative Names: NSC 306951. Grades: Highly Purified. CAS No. 55303-98-5. Pack Sizes: 1mg. Molecular Formula: C21H30O2. US Biological Life Sciences. | Worldwide |
| Avarol | Avarol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Avarol; 2-{[(1r,2s,4as,8as)-1,2,4a,5-tetramethyl-1,2,3,4,4a,7,8,8a-octahydronaphthalen-1-yl]methyl}benzene-1,4-diol; (1R-(1alpha,2beta,4abeta,8abeta))-2-((1,2,3,4,4a,7,8,8a-Octahydro-1,2,4a,5-tetramethyl-1-naphthalenyl)methyl)-1,4-benzenediol; Avrol. Product Category: Heterocyclic Organic Compound. CAS No. 55303-98-5. Molecular formula: C21H30O2. Mole weight: 314.5. Purity: 0.97. IUPACName: 2-[[(1R,2S,4aS,8aS)-1,2,4a,5-tetramethyl-2,3,4,7,8,8a-hexahydronaphthalen-1-yl]methyl]benzene-1,4-diol. Canonical SMILES: C[C@H]1CC[C@]2([C@H]([C@]1(C)CC3=C(C=CC(=C3)O)O)CCC=C2C)C. Density: 1.055g/cm³. Product ID: ACM55303985. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Avasimibe | Avasimibe inhibits Lipoprotein(a) accumulation in the culture media of primary monkey hepatocyte in a dose-dependent manner with 11.9% -31.3% inhibition, the change is mainly associated with decreased ApoA. Uses: Cytochrome p-450 cyp3a inducers. Synonyms: CI-1011; CI 1011; CI1011; ((2,4,6-Tris(1-methylethyl)phenyl)acetyl)sulfamic acid 2,6-bis(1-methylethyl)phenyl este; Sulfamic acid, N-[2-[2,4,6-tris(1-methylethyl)phenyl]acetyl]-, 2,6-bis(1-methylethyl)phenyl esterr. Grades: >98%. CAS No. 166518-60-1. Molecular formula: C29H43NO4S. Mole weight: 501.72. | |
| Avasimibe | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Avasimibe | Avasimibe. Group: Biochemicals. Alternative Names: CI 1011; PD 148515; N-[2-[2, 4, 6-tris (1-methylethyl) phenyl]acetyl]-2-sulfamic Acid 6-Bis(1-methylethyl)phenyl Ester. Grades: Highly Purified. CAS No. 166518-60-1. Pack Sizes: 25mg. Molecular Formula: C29H43NO4S, Molecular Weight: 501.72. US Biological Life Sciences. | Worldwide |
| Avasopasem manganese | Avasopasem manganese (GC4419; M-40419) is a potent superoxide dismutase mimetic that rapidly and specifically converts O 2 *- to hydrogen peroxide (H 2 O 2 ), arresting the initiation of this cascade. Avasopasem manganese can be used for the research of severe oral mucositis (SOM) and cancer [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GC-4419; M-40419. CAS No. 435327-40-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109110. | |
| Avatrombopag | Avatrombopag, also known as AKR-501, YM477, AS 1670542 or E5501, is a novel orally-active thrombopoietin (TPO) receptor agonist. AKR-501 specifically targeted the TPO receptor and stimulated megakaryocytopoiesis throughout the development and maturation of megakaryocytes just as rhTPO did. AKR-501 is an orally-active TPO receptor agonist that may be useful in the treatment of patients with thrombocytopenia. Synonyms: AKR-501; AKR 501; AKR501; YM477; YM-477; YM 477; E5501; AS 1670542; AS1670542; AS-1670542. Grades: 98%. CAS No. 570406-98-3. Molecular formula: C29H34Cl2N6O3S2. Mole weight: 649.65. | |
| Avatrombopag | Avatrombopag (AKR-501) is an orally active, nonpeptide thrombopoietin (TPO) receptor agonist ( EC 50 =3.3 nM). Avatrombopag mimics the biological activities of TPO. Avatrombopag increases platelet production by activating the intracellular signaling system, and promotes production of platelets and megakaryocytes from hemopoietic precursor cells. Avatrombopag is a substrate of cytochrome P450 (CYP) 2C9 and CYP3A [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AKR-501; E5501; YM477. CAS No. 570406-98-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13463. | |
| Avatrombopag hydrochloride | Avatrombopag (AKR-501) hydrochloride is an orally active, nonpeptide thrombopoietin (TPO) receptor agonist ( EC 50 =3.3 nM). Avatrombopag hydrochloride mimics the biological activities of TPO. Avatrombopag hydrochloride increases platelet production by activating the intracellular signaling system, and promotes production of platelets and megakaryocytes from hemopoietic precursor cells. Avatrombopag hydrochloride is a substrate of cytochrome P450 (CYP) 2C9 and CYP3A [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AKR-501 hydrochloride; E5501 hydrochloride; YM477 hydrochloride. CAS No. 570403-17-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13463B. | |
| Avatrombopag Impurity 28 | Avatrombopag Impurity 28. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: tert-butyl 4-cyclohexylpiperazine-1-carboxylate. CAS No. 1224935-95-8. Molecular formula: C15H28N2O2. Mole weight: 268.4. Catalog: APB1224935958. | |
| Avatrombopag Impurity 31 | Avatrombopag Impurity 31. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(5-chlorothiophen-2-yl)thiazol-2-amine. CAS No. 123971-45-9. Molecular formula: C7H5ClN2S2. Mole weight: 216.71. Catalog: APB123971459. | |
| Avatrombopag Impurity 82 | Avatrombopag Impurity 82. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(5-bromo-4-chlorothiophen-2-yl)thiazol-2-amine. CAS No. 1534575-19-3. Molecular formula: C7H4BrClN2S2. Mole weight: 293.87. Catalog: APB1534575193. | |
| Avatrombopag maleate | Avatrombopag, also known as AKR-501, YM477, AS 1670542 or E5501, is a novel orally-active thrombopoietin (TPO) receptor agonist. AKR-501 specifically targeted the TPO receptor and stimulated megakaryocytopoiesis throughout the development and maturation of megakaryocytes just as rhTPO did. AKR-501 is an orally-active TPO receptor agonist that may be useful in the treatment of patients with thrombocytopenia. CAS No. 677007-74-8. Molecular formula: C33H38Cl2N6O7S2. Mole weight: 765.7. | |
| Avatrombopag maleate | Avatrombopag maleate (AKR-501) is an orally active, nonpeptide thrombopoietin (TPO) receptor agonist ( EC 50 =3.3 nM). Avatrombopag maleate mimics the biological activities of TPO. Avatrombopag maleate increases platelet production by activating the intracellular signaling system, and promotes production of platelets and megakaryocytes from hemopoietic precursor cells. Avatrombopag maleate is a substrate of cytochrome P450 (CYP) 2C9 and CYP3A [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AKR-501 maleate; E5501 maleate; YM477 maleate. CAS No. 677007-74-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13463A. | |
| AvBD10 | AvBD10 is an antimicrobial peptide produced by liver, Peking duck, Anas platyrhynchos (Domestic duck). It has antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Synonyms: Duck AvBD10; Duck avian beta defensin 10; Val-Leu-Leu-Phe-Leu-Phe-Gln-Ala-Ala-Pro-Gly-Ser-Ala-Asp-Ala-Pro-Phe-Ala-Asp-Thr-Ala-Ala-Cys-Arg-Ser-Gln-Gly-Asn-Phe-Cys-Arg-Ala-Gly-Ala-Cys-Pro-Pro-Thr-Phe-Ala-Ala-Ser-Gly-Ser-Cys-His-Gly-Gly-Leu-Leu-Asn-Cys-Cys-Ala-Lys. Grades: >98%. | |
| AVB-S6-500 | AVB-S6-500 is a GAS6-AXL signaling pathway blocker with high affnity for GAS6. AVB-S6-500 is developed for the treatment of cancer and nonmalignant fibrotic conditions as a drug candidate. It is in a phase I clinical trial for its safety and tolerability study. Uses: Potential treatment of cancer and nonmalignant fibrotic conditions. Synonyms: Aravive-S6. | |
| Avdoralimab | Avdoralimab (IPH 5401) is a fully human IgGκ monoclonal antibody that targets the complement C5a receptor 1 (C5aR1) that prevents its binding to C5a. Avdoralimab can be used for complement-driven inflammatory diseases and solid tumours research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: IPH 5401; Anti-C5aR1 mAb. CAS No. 2226393-85-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99450. | |
| AVE-0118 | AVE 0118 is a potassium channel blocker that has the potential for the treatment of sleep apnea syndrome. AVE 0118 functions without apparent effect on ventricular repolarization. Noteworthy, the atrial selective and dose-dependent prolongation of atrial refractoriness (ERP) by AVE 0118 has been claimed to be an inhibitory effect of sodium channel activity in an atrial-selective manner, and may therefore contribute to the anti-AF property of AVE0118. Synonyms: [1,1'-Biphenyl]-2-carboxamide, 2'-[[[2-(4-methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl]-; 2'-[[[2-(4-Methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl][1,1'-biphenyl]-2-carboxamide; [1,1'-Biphenyl]-2-carboxamide, 2'-[[[(4-methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl]-; 2'-[[2- (4-Methoxyphenyl) acetylamino]methyl]biphenyl-2-carboxylic acid (2-pyridin-3-yl-ethyl)amide; AVE 0118; AVE0118. Grades: ≥95%. CAS No. 498577-53-0. Molecular formula: C30H29N3O3. Mole weight: 479.57. | |
| AVE 0118 hydrochloride | AVE 0118 hydrochloride is a potassium channel blocker that has the potential for the treatment of sleep apnea syndrome. AVE 0118 functions without apparent effect on ventricular repolarization. Noteworthy, the atrial selective and dose-dependent prolongation of atrial refractoriness (ERP) by AVE 0118 has been claimed to be an inhibitory effect of sodium channel activity in an atrial-selective manner, and may therefore contribute to anti-AF property of AVE0118. Synonyms: Benzeneacetamide, 4-methoxy-N-[[2'-[[[2-(3-pyridinyl)ethyl]amino]carbonyl][1,1'-biphenyl]-2-yl]methyl]-, hydrochloride (1:1); 2'-[[[2-(4-Methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl][1,1'-biphenyl]-2-carboxamide hydrochloride; [1,1'-Biphenyl]-2-carboxamide, 2'-[[[(4-methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl]-, hydrochloride; 2'-[[2- (4-Methoxyphenyl) acetylamino]methyl]biphenyl-2-carboxylic acid (2-pyridin-3-yl-ethyl)amide hydrochloride; AVE 0118 hydrochloride; AVE0118 hydrochloride. Grades: 99%. CAS No. 2108821-80-1. Molecular formula: C30H29N3O3.HCl. Mole weight: 516.03. | |
| AVE 0991 | AVE 0991 is an agonist of nonpeptide Ang-(1-7) receptor Mas that has potential as a cardiovascular drug. Synonyms: 1-ethyl-3-[3-[4-[(5-formyl-4-methoxy-2-phenylimidazol-1-yl)methyl]phenyl]-5-(2-methylpropyl)thiophen-2-yl]sulfonylurea5-formyl-4-methoxy-2-phenyl-1-((4-(2-ethyl-aminocarbonylsulfonamido-5-isobutyl-3-thienyl)phenyl)methyl)imidiazoleAVE 0991; AVE-0991; AVE0991. CAS No. 304462-19-9. Molecular formula: C29H32N4O5S2. Mole weight: 580.72. | |
| AVE 0991 sodium salt | AVE 0991 sodium salt, is an agonist of nonpeptide Ang-(1-7) receptor Mas that has potential as a cardiovascular drug. Synonyms: AVE-0991 sodium salt; AVE 0991 sodium salt; AVE0991 sodium salt; sodium;ethylcarbamoyl-[3-[4-[(5-formyl-4-methoxy-2-phenylimidazol-1-yl)methyl]phenyl]-5-(2-methylpropyl)thiophen-2-yl]sulfonylazanideAVE 0991 (sodium salt)306288-04-0C29H31N4NaO5S23195AH. CAS No. 306288-04-0. Molecular formula: C29H31N4NaO5S2. Mole weight: 602.70. | |
| Ave-1625 | Ave-1625. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AVE-1625;Drinabant. Product Category: Heterocyclic Organic Compound. Appearance: A crystalline solid. CAS No. 358970-97-5. Molecular formula: C23H20Cl2F2N2O2S. Mole weight: 497.38. Density: 1.458. Product ID: ACM358970975. Alfa Chemistry ISO 9001:2015 Certified. Categories: AVE 1625. | |
| AVE-8063 | AVE-8063 is an antimitotic agent or microtubule inhibitor with potential anticancer activity. Synonyms: AVE8063; AVE 8063; (Z)-1-(3-Amino-4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene; (Z)-2-methoxy-5-(3,4,5-trimethoxystyryl) aniline. Grades: >98%. CAS No. 162705-07-9. Molecular formula: C18H21NO4. Mole weight: 315.37. | |
| Avelumab | Avelumab is a fully human IgG1 anti- PD-L1 monoclonal antibody with potential antibody-dependent cell-mediated cytotoxicity. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human PD-L1, Human Antibody; MSB 0010718C; MSB0010718C. CAS No. 1537032-82-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-108730. | |
| Avelumab (anti-PD-L1) | Avelumab (anti-PD-L1) is a fully human IgG1 anti- PD-L1 monoclonal antibody with potential antibody-dependent cell-mediated cytotoxicity [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1537032-82-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-108730A. | |
| Avenaciolide | It is produced by the strain of Aspergillus avenaceus. A bicyclic bis-butyrolactone; isolated from aspergillus avenaceu; an antifungal agent; inhibits glutamate transport; an atypical ionophore. Synonyms: Avenaciolid; Furo(3,4-b)furan-2,6(3H,4H)-dione, dihydro-3-methylene-4-octyl- (VAN) (8CI). Grades: >95% by HPLC. CAS No. 20223-76-1. Molecular formula: C15H22O4. Mole weight: 266.33. | |
| avenacosidase | Isolated from oat (Avena sativa) seedlings. The product acts as a defense system against fungal infection. Also acts on avenacoside A. Group: Enzymes. Synonyms: As-P60. Enzyme Commission Number: EC 3.2.1.188. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3872; avenacosidase; EC 3.2.1.188; As-P60. Cat No: EXWM-3872. |  |
| Avenanthramide A | Avenanthramide A is a phytoalexin, which can be found in oats ( Avena sativa L. ). Avenanthramide A targets the RNA helicase DDX3 , leads to mitochondrial swelling and increased ROS production, and induces apoptosis in CRC cells. Avenanthramide A exhibits antitumor efficacy in mouse model. Avenanthramide A orally active [1]. Uses: Scientific research. Group: Natural products. CAS No. 108605-70-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-114977. | |
| Avenanthramide A | analytical standard. Group: Natural compoundsenzyme activators, inhibitors & substrates. | |
| Avenanthramide B | analytical standard. Group: Natural compounds. | |
| Avenanthramide C | Avenanthramide C is an orally active avenanthramide that can be isolated from oat seeds. Avenanthramide C decreases the protein expression of cleaved caspase-3 and increases the expression of p-GSK3β(Ser9) and IL-10 levels. Avenanthramide C has the potential for the research of Alzheimers disease [1]. Uses: Scientific research. Group: Natural products. CAS No. 116764-15-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-124344. | |
| Avenanthramide C | analytical standard. Group: Natural compounds. | |
| Avenanthramide-c methyl ester | Avenanthramide-c methyl ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Avenanthramide-C methyl ester, 955382-52-2, AGN-PC-00DGLK, CTK8E8646, methyl 2-[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]amino]-5-hydroxybenzoate. Product Category: Heterocyclic Organic Compound. CAS No. 955382-52-2. Molecular formula: C17H15NO6. Mole weight: 329.304100 [g/mol]. Purity: 0.96. IUPACName: methyl 2-[3-(3,4-dihydroxyphenyl)prop-2-enoylamino]-5-hydroxybenzoate. Product ID: ACM955382522. Alfa Chemistry ISO 9001:2015 Certified. | |
| Avenanthramide-C methyl ester | Avenanthramide-C methyl ester is an inhibitor of NF-κB activation that acts by blocking the phosphorylation of IKK and IκB (IC50 = 40 μM). Synonyms: Avenanthramide-C methyl ester; 955382-52-2; methyl 2-[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]amino]-5-hydroxybenzoate; SCHEMBL20963041; IUZHCICFVDHVMC-XVNBXDOJSA-N; AKOS040755114; Methyl (E)-2-(3-(3,4-dihydroxyphenyl)acrylamido)-5-hydroxybenzoate; 2-[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]amino]5-hydroxy-benzoic acid, methyl ester; 2-[[(2E)-3-(3,4-Dihydroxyphenyl)-1-oxo-2-propen-1-yl]amino]5-hydroxybenzoic acid, methyl ester. Grades: ≥90%. CAS No. 955382-52-2. Molecular formula: C17H15NO6. Mole weight: 329.3. | |
| Avenanthramide D | Synonyms: Avenanthramide 1p; Dianthramide P; N-p-Coumarylanthranilic acid; N-(E)-p-Coumaroylanthranilic acid. CAS No. 115610-36-1. Molecular formula: C16H13NO4. Mole weight: 283.28. | |
| Avena Sativa Kernel Extract | Avena Sativa Kernel Extract is a fully water-soluble botanical cosmetic raw material obtained from the kernel part of the gramineous plant oats. The main active ingredient is dextran, which is a kind of high saccharide, which can form a transparent, elastic and breathable film on the skin. Avena Sativa Kernel Extract can be used as a skin conditioner in cosmetics. Grades: 10:1. CAS No. 84012-26-0. | |
| Averantin | Averantin is an anthraquinone fungal metabolite produced by Aspergillus sp. associated with Panax notoginseng. It is a mycotoxic intermediate in the pathway to aflatoxin B1. It displays antifungal activity against Fusariumsolani (pathogenic fungus of P. notoginseng) with minimum inhibitory concentrations of 16-32 ug/mL. It also shows antibacterial activity against Bacillus subtilis with minimum inhibitory concentrations of 16-32 ug/mL. Synonyms: 1,3,6,8-Tetrahydroxy-2-[(1S)-1-hydroxyhexyl]-9,10-anthracenedione; (-)-Averantin; (S)-1,3,6,8-Tetrahydroxy-2-(1-hydroxyhexyl)-9,10-anthracenedione; 9,10-Anthracenedione, 1,3,6,8-tetrahydroxy-2-[(1S)-1-hydroxyhexyl]-; (1'S)-averantin; (S)-(-)-averantin; (S)-averantin. Grades: ≥95%. CAS No. 5803-62-3. Molecular formula: C20H20O7. Mole weight: 372.37. | |
| Averantin (BRN 2309929, 2- (1- hydroxyhexyl) -1, 3, 6, 8-tetra hydroxyanthraquinone) | Mycotoxin. Intermediate of the biosynthetic pathway to aflatoxin B1. Cytotoxic against human solid tumor cell lines. Group: Biochemicals. Grades: Highly Purified. CAS No. 5803-62-3. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| averantin hydroxylase | A heme-thiolate (P-450) monooxygenase isolated from Aspergillus parasiticus. There is no reaction with (1'R)-averantin. Involved in aflatoxin biosynthesis. Group: Enzymes. Synonyms: AVN hydroxylase; avnA (gene name); (1'S)-averantin,NADPH:O2 oxidoreductase (5'-hydroxylating). Enzyme Commission Number: EC 1.14.13.174. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0772; averantin hydroxylase; EC 1.14.13.174; AVN hydroxylase; avnA (gene name); (1'S)-averantin,NADPH:O2 oxidoreductase (5'-hydroxylating). Cat No: EXWM-0772. | |
| Avermectin A1a | Avermectin A1a is produced by the strain of Streptomyces avermitilis. It stimulates nerve cells to release Y-aminobutyric acid (GABA), which blocks the transmission of signals from the central nervous system to the motor nerve. It is not resistant to bacteria and fungi, but has strong activity to nematode parasites such as ancylostoma and Pteria, as well as insects such as flies. Abamectin B1a has the highest activity. Ivermectin obtained by catalytic hydrogenation contains 22 23- dihydroabamectin B1a (above 80%) and 22 23 dioxabamectin B1b (below 20%). Less active than B1a but less toxic. Used as repellent (subcutaneous or oral) for cattle, sheep and pigs, it is also effective against human filariasis. Synonyms: SCHEMBL1681257. CAS No. 65195-51-9. Molecular formula: C49H74O14. Mole weight: 887.10. | |
| Avermectin A2a | Avermectin A2a is produced by the strain of Streptomyces avermitilis. It stimulates nerve cells to release Y-aminobutyric acid (GABA), which blocks the transmission of signals from the central nervous system to the motor nerve. It is not resistant to bacteria and fungi, but has strong activity to nematode parasites such as ancylostoma and Pteria, as well as insects such as flies. Abamectin B1a had the highest activity. Ivermectin obtained by catalytic hydrogenation contains 22,23-dihydroabamectin B1a (above 80%) and 22,23 dioxabamectin B1b(below 20%). Less active than B1a but less toxic. Used as repellent (subcutaneous or oral) for cattle, sheep and pigs, it is also effective against human filariasis. Synonyms: Avermectin A1a; SCHEMBL1681224. CAS No. 50914-15-3. Molecular formula: C49H76O15. Mole weight: 905.12. | |
| Avermectin B1 | Avermectin B1. Group: Biochemicals. Grades: Highly Purified. CAS No. 71751-41-2. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C49H74O14. US Biological Life Sciences. | Worldwide |
| Avermectin B1a | It is produced by the strain of Streptomyces avermitilis. Avermectin B1a is an antiparasitic agent that paralyzes nematodes without causing hypercontraction or flaccid paralysis. It is a macrocyclic lactone that makes up a large component of the anthelimintic Abamectin used to control parasitic nematodes in livestock. It also acts as an insecticide and acaricide. Uses: Active ingredient in some commercial ant bait traps. Synonyms: Abamectin B1a. Grades: >98%. CAS No. 65195-55-3. Molecular formula: C48H72O14. Mole weight: 873.08. | |
| Avermectin B1a | Avermectin B1a. Group: Biochemicals. Grades: Highly Purified. CAS No. 65195-55-3. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C48H72O14. US Biological Life Sciences. | Worldwide |
| Avermectin B1a (5-O-Demethylavermectin A1a, Antibiotic C 076B1a) | Avermectin B1a is the major component (>80%) of the commerically available anthelmintic Abamectin (R) used to control parasitic nematodes in livestock. Avermectin B1a contains a secbutyl residue in the 24-position. In vitro and in vivo studies have shown this analogue is the more potent analogue in the commerical product. Group: Biochemicals. Alternative Names: 5-O-Demethylavermectin A1a, Antibiotic C 076B1a. Grades: Highly Purified. CAS No. 65195-55-3. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Our database is helping our users find suppliers everyday.
