A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Atranorin, which can be found in the herbs of Parmelia tinctorum Despr, has a relevant redox-active action, acting as a pro-oxidant or antioxidant agent depending on the radical. Also, it will exert cytoprotective effects on cells under oxidative stress induced by H(2)O(2). It was found to be more efficient at equitoxic doses and correlated more strongly with an increased number of floating cells or a higher apoptotic index. It also exhibited significant anti-inflammatory activity in the acute model of inflammation (leukocyte migration to the peritoneal cavity), carrageenan- and arachidonic acid-induced hind paw edema in rats. Besides, Atranorin exhibited a dose-dependent antioxidant activity in vitro, as assessed by total radical-trapping antioxidant parameter and total antioxidant reactivity assays. Uses: Antinociceptive/antiinflammatory/antibacterial. Synonyms: Atranoric acid; Atranorine; Parmelin; Usnarin; Benzoic acid, 3-formyl-2,4-dihydroxy-6-methyl-, 3-hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl ester. Grade: 98%. CAS No. 479-20-9. Molecular formula: C19H18O8. Mole weight: 374.34.
Atranorin
Atranorin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PARMELIN;USNARIN;ATRANORIN;3-hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl 3-formyl-2,4-dihydroxy-6-methylbenzoate;3-Formyl-2,4-dihydroxy-6-methylbenzoicacid3-hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenylester;NSC-685591;ATRANORIN(P);Atrarin. Product Category: Heterocyclic Organic Compound. Appearance: White powder. CAS No. 479-20-9. Molecular formula: C19H18O8. Mole weight: 374.4. Purity: 0.98. IUPACName: (3-hydroxy-4-methoxycarbonyl-2,5-dimethylphenyl) 3-formyl-2,4-dihydroxy-6-methylbenzoate. Canonical SMILES: CC1=CC(=C(C(=C1C(=O)OC2=C(C(=C(C(=C2)C)C(=O)OC)O)C)O)C=O)O. Product ID: ACM479209. Alfa Chemistry ISO 9001:2015 Certified.
Atranorin
Atranorin is a lichen secondary metabolite. Atranorin inhibits lung cancer cell motility and tumorigenesis by affecting AP-1, Wnt, and STAT signaling and suppressing RhoGTPase activity [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 479-20-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N2907.
Atrasentan
atrasentan hydrochloride is the orally available hydrochloride salt of pyrrolidine-3-carboxylic acid with potential antineoplastic activity. As a selective antagonist of the endothelin-A (ETA) receptor, atrasentan binds selectively to the ETA receptor, which may result in inhibition of endothelin-induced angiogenesis and tumor cell proliferation. Synonyms: US brand name: Xinlay; Code names: (+)-A 127722; ABT-627; ABT627; A 127722; A127722; A-127722; Xinlay; ABT 627; NSC720763; NSC 720763; NSC-720763. CAS No. 173937-91-2. Molecular formula: C29H38N2O6. Mole weight: 510.631.
Atrasentan
Atrasentan (ABT-627) is an endothelin receptor antagonist with IC 50 of 0.0551 nM for ET A [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-627; (+)-A 127722; A-147627. CAS No. 173937-91-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15403.
Atrasentan hydrochloride
Atrasentan hydrochloride (ABT-627 hydrochloride) is a selective endothelin A receptor antagonist with an IC 50 of 0.0551 nM for ET A [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-627 hydrochloride; (+)-A 127722 hydrochloride; A-147627 hydrochloride. CAS No. 195733-43-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15403A.
Atrasentan hydrochloride is the hydrochloride salt form of Atrasentan. Atrasentan, also called as ABT-627, is a selective and orally available antagonist of ETA receptor with potent antitumour activity. Synonyms: Atrasentan Hydrochloride; Atrasentan HCl; A 147627; A-147627; A147627; (2R,3R,4S)-4-(1,3-benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid; hydrochlorideAtrasentan hydrochlorideAtrasentan HCl195733-43-8Atrasentan (hydrochloride)UNII-E4G31X93ZAAbbott 147627Atrasentan hydr. Grade: 95%. CAS No. 195733-43-8. Molecular formula: C29H39ClN2O6. Mole weight: 547.08.
Atrazine, a triazine herbicide, is principally used for control of certain annual broadleaf and grass weeds. Atrazine inhibits photophosphorylation but typically does not result in lethality or permanent cell damage in the short term [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1912-24-9. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-N7091.
Atrazine
Selective herbicide. Potential symptoms of overexposure are irritation of eyes and skin; dermatitis, skin sensitization; dyspnea, weakness, incoordination, salivation; hypothermia; liver injury. Group: Biochemicals. Alternative Names: 6-Chloro-N-ethyl-N'-(1-methylethyl)-1,3,5-triazine-2,4-diamine;2-Chloro-4-(ethylamino)-6-(2-propylamino)-s-triazine; AAtrex; Gesamprim; Gesaprim; Gesaprim. Grades: Highly Purified. CAS No. 1912-24-9. Pack Sizes: 5g. US Biological Life Sciences.
Worldwide
Atrazine
5mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C8H14ClN5. CAS No. 1912-24-9. Prepack ID 64291709-5mg. Molecular Weight 215.68. See USA prepack pricing.
Atrazine-13C4
Atrazine-13C4 is the isotope labelled analog of Atrazine (A794600); a selective herbicide. Potential symptoms of overexposure to Atrazine are irritation of eyes and skin, dermatitis, skin sensitization, dyspnea, weakness, incoordination, salivation, hypothermia, and liver injury. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C413C4H14ClN5, Molecular Weight: 219.65. US Biological Life Sciences.
Worldwide
Atrazine-[15N]
Atrazine-[15N] is the labelled analogue of Atrazine. Synonyms: Atrazine-(ethylamino-15N); 2-Chloro-4-ethylamino-15N-6-isopropylamino-1,3,5-triazine. Grade: 98% by CP; 99% atom 15N. CAS No. 287476-17-9. Molecular formula: C8H14ClN4[15N]. Mole weight: 216.68.
Atrazine-2-hydroxy. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-Ethylamino-6-(Propan-2-Ylamino)-5H-1,3,5-Triazin-2-One; 4-(ethylamino)-6-(isopropylamino)-s-triazin-2-ol; N-ethyl-6-hydroxy-N-(1-methylethyl)-1,3,5-triazine-2,4-diamine; Hydroxy Atrazine; 2-hydroxypropazine; 6-hydroxy-N-2-ethyl-N-4-isopropyl-1,3,5-triazine-2,4-diamine; 2-Hydroxy-4-ethylamino-6-isopropylamino-1,3,5-triazine; 2-(ethylamino)-6-(propan-2-ylamino)-1H-1,3,5-triazin-4-one; Atrazine-2-hydroxy; hydroxydechloroatrazine; Hydroxyatrazine; 2-Hydroxyatrazine; 2-hydroxy-4-ethylamino-6-[1-methylethyl]-1,3,5-triazine-2,4-diamine; 4-(Ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine; 6-hydroxy-N2-ethyl-N4-(1-methylethyl)-1,3,5-triazine-2,4-diamine. Appearance: solid. CAS No. 2163-68-0. Molecular formula: C8H15N5O. Mole weight: 197.24. Purity: analytical standard. IUPACName: 2-(ethylamino)-6-(propan-2-ylamino)-1H-1,3,5-triazin-4-one. Canonical SMILES: CCNC1=NC(=O)N=C(N1)NC(C)C. Density: 1.3g/cm³. Product ID: ACM2163680. Alfa Chemistry ISO 9001:2015 Certified.
atrazine chlorohydrolase
Involved in the degradation of the herbicide atrazine, 2-chloro-4-(ethylamino)-6-(isopropylamino)-1,3,5-triazine, in bacteria. Group: Enzymes. Synonyms: AtzA. Enzyme Commission Number: EC 3.8.1.8. CAS No. 168680-16-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4747; atrazine chlorohydrolase; EC 3.8.1.8; 168680-16-8; AtzA. Cat No: EXWM-4747.
Atrazine-d5
Atrazine-d 5 is deuterium labeled Atrazine. Atrazine is principally used for control of certain annual broadleaf and grass weeds. Atrazine inhibits photophosphorylation but typically does not result in lethality or permanent cell damage in the short term[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 163165-75-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N7091S2.
Atrazine-d5
Labeled selective herbicide. Potential symptoms of overexposure are irritation of eyes and skin; dermatitis, skin sensitization; dyspnea, weakness, incoordination, salivation; hypothermia; liver injury. Group: Biochemicals. Alternative Names: 6-Chloro-N-(ethyl-d5)-N'-(1-methylethyl)-1,3,5-triazine-2,4-diamine;2-Chloro-4-(ethylamino-d5)-6-(2-propylamino)-s-triazine; AAtrex-d5; Gesamprim-d5; Gesaprim-d5; Gesaprim-d5. Grades: Highly Purified. CAS No. 163165-75-1. Pack Sizes: 1mg. US Biological Life Sciences.
Atrazine-[d5] is the labelled analogue of Atrazine, which is a selective herbicide. Synonyms: Atrazine-d5; 6-Chloro-N-(ethyl-d5)-N'-(1-methylethyl)-1,3,5-triazine-2,4-diamine; 2-Chloro-4-(ethylamino-d5)-6-(2-propylamino)-s-triazine; Gesamprim-d5. Grade: ≥97%; ≥98% atom D. CAS No. 163165-75-1. Molecular formula: C8H9D5ClN5. Mole weight: 220.72.
Atrazine-[d7]
Atrazine-[d7] is the labelled analogue of Atrazine, which is a selective herbicide. Synonyms: Atrazine-D7; 6-Chloro-N-ethyl-N'-isopropyl-D7-[1,3,5]triazine-2,4-diamin; Gesaprim-d7; Atrazin-d7; Chromozin-d7; Oleogesaprim-d7; Aktikon-d7; Argezin-d7. Grade: 95% by HPLC; 98% atom D. Molecular formula: C8H7D7ClN5. Mole weight: 222.73.
Atrazine-desethyl-[d7] is the labelled analogue of Atrazine-desethyl, which has been shown to inhibit the growth of plants. Synonyms: 6-Chloro-N-isopropyl-D7-1,3,5-triazine-2,4-diamine; Atrazine-desethyl-D7; 2-Amino-4-(isopropyl-d7-amino)-6-chloro-triazine; Desethylatrazine-d7. Grade: ≥97% by HPLC; ≥99% atom D. CAS No. 1216649-31-8. Molecular formula: C6H3D7ClN5. Mole weight: 194.67.
Atrazine glutathione adduct. Group: Biochemicals. Alternative Names: L-gamma-Glutamyl-S-[4-(ethylamino)-6-[(1-methylethyl)amino]-1,3,5-triazin-2-yl]-L-cysteinylglycine; S-(4-Ethylamino-6-isopropylamino-2-s-triazino)glutathione; Glutathione S-atrazine. Grades: Highly Purified. CAS No. 24429-05-8. Pack Sizes: 50mg, 100mg. Molecular Formula: C18H30N8O6S. US Biological Life Sciences.
Worldwide
Atrazine Mercapturate Hydrochloride
The major metabolite of Atrazine (ATR) in human urine. Group: Biochemicals. Alternative Names: N-Acetyl-S-[4-(ethylamino)-6-[(1-methylethyl)amino]-1,3,5-triazin-2-yl]-L-cysteine Hydrochloride; ATR-Mercap Hydrochloride. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Atrazine (Standard)
Atrazine (Standard) is the analytical standard of Atrazine. This product is intended for research and analytical applications. Atrazine is principally used for control of certain annual broadleaf and grass weeds. Atrazine inhibits photophosphorylation but typically does not result in lethality or permanent cell damage in the short term [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1912-24-9. Pack Sizes: 50 mg; 100 mg; 250 mg. Product ID: HY-N7091R.
Atrazine-(triazyl-13C3,15N3)
?98 atom %, ?98% (CP). Group: Fluorescence/luminescence spectroscopy.
A cell-permeable, pyrimidine derivative that acts as an ATP-competitive CDK Inhibitor (Ki=2.5uM for CDK1, and Ki=1.3uM for CDK2), and demonstrates cytostatic properties among a panel of 57 cancer cell lines. Also inhibits ATR kinase (IC50=6.7uM in MCF7 cells), but does not interfere with irradiation-induced autophosphorylation of DNA-PK or ATM. Potentiates a range of DNA-damaging cytotoxic drugs such as hydroxyurea (1.8-fold) and cisplatin (1.4-fold) at 10uM, but not the anti-mitotic paclitaxel. Attenuates G2/M arrest following DNA damage and inhibits RAD51 focus formation. Shown to be synthetically lethal when DNA single-strand break repair is impaired in PARP-inhibited cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 220036-08-8. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Atreleuton
Atreleuton, a kind of urea compound, has been found to be a 5-lipoxygenase inhibitor as well as Leukotriene B4 receptor antagonist that could probably be useful in study of sorts of diseases like asthma and acute coronary syndromes. It has already been discontinued by VIA Pharmaceuticals. Uses: Lipoxygenase inhibitors. Synonyms: Atreleuton; ABT-761; ABT 761; VIA 2291; VIA-2291; VIA2291; A-85761; Abbott-85761; Atreleuton [USAN]; UNII-U301T88E1M; ABT 761; 1-[(2R)-4-[5-[(4-fluorophenyl)methyl]thiophen-2-yl]but-3-yn-2-yl]-1-hydroxyurea. Grade: 98%. CAS No. 154355-76-7. Molecular formula: C16H15FN2O2S. Mole weight: 318.37.
Atreleuton-[d4] is a labelled Atreleuton. Atreleuton is a 5-lipoxygenase inhibitor that has the potential to treat acute coronary syndrome. Synonyms: (2R)-4-(5-{[4-fluoro(2H4)phenyl]methyl}thiophen-2-yl)-N-hydroxy-N-(C-hydroxycarbonimidoyl)but-3-yn-2-amine. Grade: 95% by HPLC; 98% atom D. Molecular formula: C16H11D4FN2O2S. Mole weight: 322.39.
Atreleuton Glucuronide
Atreleuton Glucuronide is an esteemed compound of profound significance, used for studying afflictions of inflammation and autoimmune disorders. Its unparalleled prowess lies in the inhibition of 5-lipoxygenase activity, thereby efficaciously studying the research and development of leukotrienes. Molecular formula: C22H22FN2O8S. Mole weight: 493.48.
Atrial natriuretic factor (1-28) (human, porcine)
Atrial natriuretic factor (1-28) (human, porcine) is a 28 amino acid peptide corresponding to the rat protein sequence. It is an endogenous peptide synthesized in myoendocrine cells of the heart from which it is released into the circulation. It has effects on the renal and cardiovascular systems that decrease vasoconstriction, increase sodium excretion and inhibit renin secretion. It decreases plasma renin activity and cAMP levels in anesthetized rats and increases cGMP levels at 8 μg/kg. It also inhibits arginine vasopressin-induced increase in mean arterial blood pressure in spontaneously hypertensive and control rats when administered intracerebroventricularly at a dose of 150 ng. It produces diuretic, natriuretic and vasodilatory effects through stimulation of guanylate cyclase-linked NPR-A receptors. It plays an important role in blood volume and blood pressure regulation. Synonyms: ANF 1-28; hANF; Atrial Natriuretic Peptide human. CAS No. 91917-63-4. Molecular formula: C127H205N45O39S3. Mole weight: 3080.46.
Atrial natriuretic peptide(126-149)(rat). Uses: Designed for use in research and industrial production. Additional or Alternative Names: ANP (126-149) (RAT);ANP (4-27), RAT;H-ARG-SER-SER-CYS-PHE-GLY-GLY-ARG-ILE-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-OH;AURICULIN A, RAT;ATRIAL NATRIURETIC PEPTIDE (126-149) (RAT);ATRIAL NATRIURETIC PEPTIDE (4-27), RAT;atrialnatriureticf. Product Category: Heterocyclic Organic Compound. CAS No. 91421-87-3. Molecular formula: C104H168N38O33S2. Mole weight: 2542.81. Product ID: ACM91421873. Alfa Chemistry ISO 9001:2015 Certified.
It is a 28-amino acid hormone that inhibits the secretion of endothelin-1 in a dose-dependent manner. Normally, it is produced and secreted by the human heart in response to cardiac injury and mechanical stretching. Synonyms: Atrial Natriuretic Factor (1-28) (human) acetate salt; H-Ser-Leu-Arg-Arg-Ser-Ser-Cys(1)-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys(1)-Asn-Ser-Phe-Arg-Tyr-OH.CH3CO2H; L-seryl-L-leucyl-L-arginyl-L-arginyl-L-seryl-L-seryl-L-cysteinyl-L-phenylalanyl-glycyl-glycyl-L-arginyl-L-methionyl-L-alpha-aspartyl-L-arginyl-L-isoleucyl-glycyl-L-alanyl-L-glutaminyl-L-seryl-glycyl-L-leucyl-glycyl-L-cysteinyl-L-asparagyl-L-seryl-L-phenylalanyl-L-arginyl-L-tyrosine (7->23)-disulfide acetic acid. Grade: ≥95%. CAS No. 1366000-58-9. Molecular formula: C127H203N45O39S3.C2H4O2. Mole weight: 3140.50.
Atrial Natriuretic Peptide (ANP) (1-28), rat
Atrial natriuretic factor (1-28) (rat) is a 28 amino acid peptide corresponding to the rat protein sequence. It is an endogenous peptide synthesized in myoendocrine cells of the heart from which it is released into the circulation. It has effects on the renal and cardiovascular systems that decrease vasoconstriction, increase sodium excretion and inhibit renin secretion. It decreases plasma renin activity and cAMP levels in anesthetized rats and increases cGMP levels at 8 μg/kg. It also inhibits the arginine vasopressin-induced increase in mean arterial blood pressure in spontaneously hypertensive and control rats when administered intracerebroventricularly at a dose of 150 ng. It produces diuretic, natriuretic and vasodilatory effects through stimulation of guanylate cyclase-linked NPR-A receptors. It plays an important role in blood volume and blood pressure regulation. Uses: Vasodilator agents. Synonyms: Atrial natriuretic factor (1-28) (rat); rANP; Atrial Natriuretic Peptide rat; Cardiodilatin-126; Atrial Natriuretic Factor (1-28) (mouse, rabbit, rat); rANF (1-28); H-Ser-Leu-Arg-Arg-Ser-Ser-Cys(1)-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys(1)-Asn-Ser-Phe-Arg-Tyr-OH; L-seryl-L-leucyl-L-arginyl-L-arginyl-L-seryl-L-seryl-L-cysteinyl-L-phenylalanyl-glycyl-glycyl-L-arginyl-L-isole. Grade: ≥95%. CAS No. 88898-17-3. Molecular formula: C128H205N45O39S2. Mole weight: 3062
Atrial Natriuretic Peptide (ANP) (1-28), rat, mouse
Atrial Natriuretic Peptide (ANP) (1-28), rat, mouse is a major circulating form of ANP in rats, potently inhibits Angiotensin II (Ang II)-stimulated endothelin-1 secretion in a concentration-dependent manner. Uses: Scientific research. Group: Peptides. Alternative Names: Atrial natriuretic factor (1-28) (rat, mouse). CAS No. 88898-17-3. Pack Sizes: 500 ?g; 1 mg; 5 mg. Product ID: HY-P1236.
Atrial Natriuretic Peptide (ANP) (1-28), rat TFA
Atrial Natriuretic Peptide (ANP) (1-28), rat TFA is a 28 amino acid peptide corresponding to the rat protein sequence. It is an endogenous peptide synthesized in myoendocrine cells of the heart from which it is released into the circulation. It has effects on the renal and cardiovascular systems that decrease vasoconstriction, increase sodium excretion and inhibit renin secretion. Synonyms: Atrial natriuretic factor (1-28) (rat) (TFA); H-Ser-Leu-Arg-Arg-Ser-Ser-Cys(1)-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys(1)-Asn-Ser-Phe-Arg-Tyr-OH.TFA; L-seryl-L-leucyl-L-arginyl-L-arginyl-L-seryl-L-seryl-L-cysteinyl-L-phenylalanyl-glycyl-glycyl-L-arginyl-L-isoleucyl-L-alpha-aspartyl-L-arginyl-L-isoleucyl-glycyl-L-alanyl-L-glutaminyl-L-seryl-glycyl-L-leucyl-glycyl-L-cysteinyl-L-asparagyl-L-seryl-L-phenylalanyl-L-arginyl-L-tyrosine (7->23)-disulfide trifluoroacetic acid. Grade: >98%. Molecular formula: C128H205N45O39S2.C2HF3O2. Mole weight: 3176.43.
a-Trifluoroacetyl-g-butyrolactone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: A-TRIFLUOROACETYL-G-BUTYROLACTONE;2(3H)-Furanone, dihydro-3-(trifluoroacetyl)- (9CI). Product Category: Heterocyclic Organic Compound. CAS No. 69243-04-5. Molecular formula: C6H5F3O3. Mole weight: 182.1. Product ID: ACM69243045. Alfa Chemistry ISO 9001:2015 Certified.
Atrimustine
Atrimustine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Bestrabucil, Atrimustine, Atrimustinum [INN-Latin], Atrimustina [INN-Spanish], KM 2210, KM-2210, Estradiol 3-benzoate 17-glycolate, 4-(p-(bis(2-chloroethyl)amino)phenyl)butyrate, Estra-1,3,5(10)-triene-3,17-diol, (17-beta)-, 3-benzoate, 17-((4-(4-(bis(2-chloroethyl)amino)phenyl)-1-oxobutoxy)acetate), Atrimustina, Atrimustinum, Atrimustine [INN], AC1L1EE9, UNII-XC0K09B7K4, C41H47Cl2NO6, 75219-46-4, Estra-1,3,5(10)-triene-3,17-diol (17beta)-, 3-benzoate 17-((4-(4-(bis(2-chloroethyl)amino)phenyl)-1-oxobutoxy)acetate), LS-64756, [(17S)-17-[2-[4-[4-[bis(2-chloroethyl)amino]phenyl]butanoyloxy]acetyl]oxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] benzoate. Product Category: Heterocyclic Organic Compound. CAS No. 75219-46-4. Molecular formula: C41H47Cl2NO6. Mole weight: 720.72. Purity: 0.96. IUPACName: [(17S)-17-[2-[4-[4-[bis(2-chloroethyl)amino]phenyl]butanoyloxy]acetyl]oxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] benzoate. Canonical SMILES: CC12CCC3C(C1CCC2OC(=O)COC(=O)CCCC4=CC=C(C=C4)N(CCCl)CCCl)CCC5=C3C=CC(=C5)OC(=O)C6=CC=CC=C6. Product ID: ACM75219464. Alfa Chemistry ISO 9001:2015 Certified.
Atrimustine
Atrimustine is a conjugate of chlorambucil and β-estradiol benzoate with the antitumor activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Bestrabucil; KM2210. CAS No. 75219-46-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101604.
ATR-IN-10
ATR-IN-10 is a potent and highly selective inhibitor of ataxia telangiectasia mutated and Rad3-Related (ATR) kinase with an IC50 value of 2.978 μM. Synonyms: ATR-IN-10; CHEMBL5188769; BDBM50603737; HY-144214; CS-0378512; 2713577-93-4. CAS No. 2713577-93-4. Molecular formula: C27H24N4O. Mole weight: 420.51.
ATR-IN-4
ATR-IN-4 is a potent ATR inhibitor. It inhibits growth of human prostate cancer cells DU145 and human lung cancer cells NCI-H460 with IC50s of 130.9 nM and 41.33 nM, respectively. CAS No. 2574545-45-0. Molecular formula: C18H20N8O. Mole weight: 364.40.
ATR inhibitor 1
ATR inhibitor 1 is an ATR inhibitor and has a Ki value below 1 μΜ. CAS No. 1613200-51-3. Molecular formula: C16H12F2N8O. Mole weight: 370.32.
ATR Inhibitor IV (VE821, 3-amino-6- (4- (methylsulfonyl) phenyl) -N-phenylpyrazine-2-carboxamide, VE-821, ATM and Rad3-Related Inhibitor IV)
A cell-permeable phenylpyrazine derivative that acts as a potent, ATP-competitive (Ki= 13nM; IC50/[ATP] = 70nM/50uM and 128nM/100uM), ATR-selective inhibitor with much reduced or little potency against 4 related PIKKs (Ki= 2.2, 3.9, 16, and >1uM, respectively, against DNA-PK, PI 3-K-gamma, ATM, and mTOR) and 50 other kinases. Shown to selectively inhibit ATR-dependent H2AX Ser139 & Chk1 Ser345 phosphorylation (complete inhibition at 10uM in HT29 and HFL1 cultures) without affecting ATM- and DNA-PK-mediated H2AX or ATM-mediated Chk2 phosphorylation. Short-term (24h) VE-821 treatment, either alone or in synergy with Cisplatin, results in reversible cytostatic growth arrest regardless of cellular ATM-p53 pathway activity, while cytotoxicity and Cisplatin synergism in cell death induction is reported to occur only upon long-term VE-821 exposure (≥72h) in cultures with ATM-p53 pathway defects.CAS No.1232410-49-10. Group: Biochemicals. Grades: Highly Purified. CAS No. 1232410-49-10. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?S. US Biological Life Sciences.
Worldwide
a-Tripiperideine
a-Tripiperideine. Group: Biochemicals. Alternative Names: Dodecahydro-1H,6H,11H-tripyrido[1,2-a:1',2'-c:1'',2''-e]-s-triazine; Dodecahydro-1H,6H,11H-tripyrido[1,2-a:1',2'-c:1'',2''-e]-s-triazine; NSC 405568. Grades: Highly Purified. CAS No. 522-33-8. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C15H27N3. US Biological Life Sciences.
Worldwide
ATR Kinase Inhibitor II (3-Amino-6-(4-((1-(dimethylamino)propan-2-yl)sulfonyl)-phenyl)-N-phenylpyrazine-2-carboxamide)
A cell-permeable aminopyrazinyl-sulfone compound that acts as a potent, reversible and ATP-competitive inhibitor of ATR kinase (IC50 = 12nM; Ki=6nM) with excellent selectivity over ATM, DNA-PK (IC50 > 8uM) and in a 50-kinase panel (% inhibition at 2uM = 59, 57, 55, 52, 43 and 42 for AMPK, Lck, RIPK2, Ret, IKK-alpha and FGFR3, respectively). Shown to block pH2AX-Ser139 (IC50 = 420nM in hydroxyurea treated HT29 cells) and preferentially enhance cisplatin cytotoxicity against tumor cells over normal cells by ~7-fold at 620nM. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?S. US Biological Life Sciences.
Worldwide
atrolysin A
A hemorrhagic endopeptidase of 68 kDa, one of six hemorrhagic toxins in the venom of western diamondback rattlesnake. The 60 kDa hemorrhagic toxin 1 of Crotalus ruber ruber shows identical specificity. In peptidase family M12 (astacin family). Related metalloendopeptidases from rattlesnake venoms are EC 3.4.24.41 (atrolysin B), EC 3.4.24.42 (atrolysin C), EC 3.4.24.43 (atroxase), EC 3.4.24.44 (atrolysin E), EC 3.4.24.45 (atrolysin F), EC 3.4.24.46 (adamalysin), EC 3.4.24.47 (horrilysin), and EC 3.4.24.48 (ruberlysin). Group: Enzymes. Synonyms: Crotalus atrox metalloendopeptidase a; hemorrhagic toxin a; Crotalus atrox α-proteinase; Crotalus atrox proteinase; bothropasin. Enzyme Commission Number: EC 3.4.24.1. CAS No. 37288-82-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4291; atrolysin A; EC 3.4.24.1; 37288-82-7; Crotalus atrox metalloendopeptidase a; hemorrhagic toxin a; Crotalus atrox α-proteinase; Crotalus atrox proteinase; bothropasin. Cat No: EXWM-4291.
atrolysin B
From the venom of the western diamondback rattlesnake (Crotalus atrox). In peptidase family M12 (astacin family). Group: Enzymes. Synonyms: Crotalus atrox metalloendopeptidase b; hemorrhagic toxin b; Ht-b. Enzyme Commission Number: EC 3.4.24.41. CAS No. 172306-48-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4323; atrolysin B; EC 3.4.24.41; 172306-48-8; Crotalus atrox metalloendopeptidase b; hemorrhagic toxin b; Ht-b. Cat No: EXWM-4323.
atrolysin C
A 24 kDa hemorrhagic endopeptidase from the venom of the western diamondback rattlesnake (Crotalus atrox) that digests type IV collagen, and exists as two forms, c and d. Phosphoramidon inhibits in the 0.1 mM range. In peptidase family M12 (astacin family). Hemorrhagic toxin-2 of C. ruber ruber has the same Mr and specificity and is a homologue. Group: Enzymes. Synonyms: Crotalus atrox metalloendopeptidase c; hemorrhagic toxin c and d. Enzyme Commission Number: EC 3.4.24.42. CAS No. 158886-17-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4324; atrolysin C; EC 3.4.24.42; 158886-17-0; Crotalus atrox metalloendopeptidase c; hemorrhagic toxin c and d. Cat No: EXWM-4324.
atrolysin E
A 25.7 kDa hemorrhagic endopeptidase from the venom of the western diamondback rattlesnake (Crotalus atrox) that digests basement membrane components, including the triple helix of type IV collagen. Such action is believed to contribute to the hemorrhagic property by weakening capillary walls. In peptidase family M12 (astacin family). Group: Enzymes. Synonyms: Crotalus atrox metalloendopeptidase e; hemorrhagic toxin e. Enzyme Commission Number: EC 3.4.24.44. CAS No. 172306-51-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4326; atrolysin E; EC 3.4.24.44; 172306-51-3; Crotalus atrox metalloendopeptidase e; hemorrhagic toxin e. Cat No: EXWM-4326.
atrolysin F
A 64 kDa hemorrhagic endopeptidase from the venom of the western diamondback rattlesnake (Crotalus atrox) that digests the γ chain of fibrinogen. Immunologically distinct from EC 3.4.24.1, atrolysin A. Group: Enzymes. Synonyms: Crotalus atrox metalloendopeptidase; hemorrhagic toxin f; Crotalus atrox metalloendopeptidase f. Enzyme Commission Number: EC 3.4.24.45. CAS No. 172306-52-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4327; atrolysin F; EC 3.4.24.45; 172306-52-4; Crotalus atrox metalloendopeptidase; hemorrhagic toxin f; Crotalus atrox metalloendopeptidase f. Cat No: EXWM-4327.
Atropine
Atropine (Tropine tropate) is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC50 values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively. Atropine inhibits ACh-induced relaxations in human pulmonary veins. Atropine can be used for research of anti-myopia and bradycardia[1][2][3][4]. Uses: Scientific research. Group: Natural products. Alternative Names: Tropine tropate; DL-Hyoscyamine. CAS No. 51-55-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-B1205.
Atropine
25g Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C17H23NO3. CAS No. 51-55-8. Prepack ID 40489627-25g. Molecular Weight 289.37. See USA prepack pricing.
Atropine
Atropine is an alkaloid as an nerve agent that occurs naturally in plants of the nightshade family. Uses: Used as a pesticide poisoning and as a muscle relaxant when injected intravenously. Synonyms: (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 3-hydroxy-2-phenylpropanoate; L-Hyoscyamine; Hyoscyamine. Grade: ≥98%. CAS No. 51-55-8. Molecular formula: C17H23NO3. Mole weight: 289.37.
Atropine
Atropine. Group: Biochemicals. Grades: Highly Purified. CAS No. 51-55-8. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C17H23NO3. US Biological Life Sciences.
Worldwide
Atropine-d5
Labeled Atropine. Mydriatic; antispasmodic; used in preanesthetic medication. Group: Biochemicals. Alternative Names: α - (Hydroxymethyl) benzeneacetic Acid-d5 (3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl Ester; Atropisol-d5; Atropt-d5; Atropin-d5; (+/-)-Hyoscyamine-d5; Tropine-d5 (+/-)-Tropate; dl-Hyoscyamine-d5; dl-Tropyl Tropate-d5. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Atropine impurity E
Anisodamine is a alkaloid shown to be a weak antagonist of α1-adrenoceptors, blocking WB-4101 and clonidine by binding in brain membrane preparations. Uses: A weak antagonist of α1-adrenoceptors. Synonyms: 654-II; 654II; 654 II; 7-hydroxyhyoscyamine; 6-Hydroxy hyoscyamine; αS-(hydroxymethyl)-benzeneacetic acid, (1R,?3S,?5R,?6S)-6-hydroxy-8-methyl-8-azabicyclo[3.2.1]?oct-3-yl ester. Grade: ≥98%. CAS No. 55869-99-3. Molecular formula: C17H23NO4. Mole weight: 305.37.