A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Ac-Arg-Cys-Met-5-aminopentanoyl-Arg-Val-Tyr-5-aminopentanoyl-Cys-NH2 is a full competitive MCH-1 receptor antagonist and has no agonist effect on human MCH-1 receptor even at micromolar concentrations (Kb = 3.6 nM). Synonyms: Ac-Arg-Cys-Met-Ava-Arg-Val-Tyr-Ava-Cys-NH2 (Disulfide bridge: Cys2-Cys9); L-Cysteinamide, N2-acetyl-L-arginyl-L-cysteinyl-L-methionyl-5-aminopentanoyl-L-arginyl-L-valyl-L-tyrosyl-5-aminopentanoyl-, cyclic (2?9)-disulfide. Grades: ≥95%. CAS No. 353487-64-6. Molecular formula: C49H82N16O11S3. Mole weight: 1167.49.
Ac-Arg-Gly-Lys-AMC
Ac-Arg-Gly-Lys-AMC is a control for the two step histone deacetylase assay with Ac-Arg-Gly-Lys(Ac)-AMC. It corresponds to the product of the deacetylase reaction, which is subsequently cleaved by trypsin. Synonyms: Ac-RGK-AMC; N2-Acetyl-L-arginylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-Lysinamide; N2-Acetyl-L-arginylglycyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-lysinamide; (S)-2-(2-((S)-2-acetamido-5-guanidinopentanamido)acetamido)-6-amino-N-(4-methyl-2-oxo-2H-chromen-7-yl)hexanamide. Grades: ≥95%. CAS No. 660846-99-1. Molecular formula: C26H38N8O6. Mole weight: 558.64.
Ac-Arg-Leu-Arg-AMC
Ac-Arg-Leu-Arg-AMC is a fluorogenic substrate for the determination of the trypsin-like activity of purified proteasomes (Km = 78 μM). Synonyms: Ac-RLR-AMC; N2-Acetyl-L-arginyl-L-leucyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-argininamide; L-Argininamide, N2-acetyl-L-arginyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-. Grades: ≥95%. CAS No. 929903-87-7. Molecular formula: C30H46N10O6. Mole weight: 642.76.
Ac-Arg-OH is an N-acetyl-L-amino acid that is L-arginine in which one of the hydrogens attached to the nitrogen is replaced by an acetyl group. It has a role as a human metabolite. It is a conjugate acid of a N(alpha)-acetyl-L-argininate. Synonyms: N-Acetyl-L-arginine; N2-Acetyl-L-arginine; Ac-Arg-OH; N-ALPHA-L-ACETYL-ARGININE; L-Arginine, N2-acetyl-; acetyl arginine; Arginine, N2-acetyl-; n-acetylarginine; (S)-2-Acetamido-5-guanidinopentanoic acid; N-ALPHA-ACETYL-L-ARGININE; N-a-Acetyl-L-arginine; N-Ac-L-Arg-OH; (2S)-2-acetamido-5-(diaminomethylideneamino)pentanoic acid; Ac Arg OH. Grades: ≥ 97%. CAS No. 155-84-0. Molecular formula: C8H16N4O3. Mole weight: 216.24.
a-Carrageenan
a-Carrageenan is a biopolymer extracted from red seaweed, exhibiting its significance in pharmaceutical applications as a stabilizer and thickening compound due to its organic nature. With its remarkable capability to form gels and bind water, this polysaccharide plays a pivotal role in the development of drug administration techniques. CAS No. 104781-83-1. Molecular formula: C24H34O31S4. Mole weight: 946.77.
Acarviosin
Acarviosin is a potent pharmaceutical compound primarily employed in the research of diabetes and metabolic anomalies, exerts its effects through the remarkable inhibition of the enzymatic activity of alpha-glucosidase. Synonyms: [1S-(1a,4a,5b,6a)]-4,6-Dideoxy-4-[[4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-a-D-glucopyranoside methyl ester 4,6-Dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-a-D-glucopyranoside methyl ester. CAS No. 80943-41-5. Molecular formula: C14H25NO8. Mole weight: 335.35.
Ac-Asp(5)-AVP
Ac-Asp(5)-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: Ac-Asp(5)-Vasopressin; N-Ac-Asp(5)-AVP; [Cys(Ac)1-Asp(5)]-Argipressin; Ac-Cys-Tyr-Phe-Gln-Asp-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); Acetyl-L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-aspartyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide. CAS No. 2594426-06-7. Molecular formula: C48H66N14O14S2. Mole weight: 1127.26.
Ac-Asp-Glu-Val-Asp-pNA is the caspase-3 chromogenic substrate, and its cleavage can be monitored at 405 nm. Synonyms: Ac-DEVD-pNA; N-acetyl-L-alpha-aspartyl-L-alpha-glutamyl-L-valyl-N4-(4-nitrophenyl)-L-asparagine; L-α-Asparagine, N-acetyl-L-α-aspartyl-L-α-glutamyl-L-valyl-N-(4-nitrophenyl)-; (2S,5S,8S,11S)-8-(2-carboxyethyl)-11-(carboxymethyl)-5-isopropyl-2-(2-((4-nitrophenyl)amino)-2-oxoethyl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazatetradecan-1-oic acid. Grades: ≥95%. CAS No. 189684-50-2. Molecular formula: C26H34N6O13. Mole weight: 638.59.
Acasunlimab (GEN1046) is a bispecific antibody (bsAb) targeting PD-L1 and 4-1BB. Acasunlimab enhances T-cell and NK-cell function through conditional 4-1BB stimulation while constitutively blocking the PD-1/PD-L1 inhibitory axis. Acasunlimab can be used in research of cancer [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: GEN1046. CAS No. 2253937-12-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99419.
Acaterin
Acarbose is an acyl-CoA isolated from Pseudomonas species. A92. In the presence of oxidized low-density lipoprotein in macrophages J744, the synthesis of cholesterol enzymes is inhibited, with an IC50 of 45 μmol/L, and the IC50 for inhibiting ACAT in rat liver microsomes is 120 μmol/L. Inhibition of ACAT is non-competitive Sexual. Synonyms: (2R)-4-[(1R)-1-hydroxyoctyl]-2-methyl-2H-furan-5-one; 3-(1-Hydroxyoctyl)-5-methyl-2(5H)-furanone. Grades: >98%. CAS No. 144398-20-9. Molecular formula: C13H22O3. Mole weight: 226.31.
Ac-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: Vasopressin, N-acetyl-8-L-arginine-; Vasopressin, 1-(N-acetyl-L-cysteine)-8-arginine; Vasopressin, 8-acetylarginine; 1-Acetylcysteine-8-arginine-vasopressin; N-Acetyl-Vasopressin; N-acetyl-L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide; Ac-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); Ac-Vasopressin; N-Acetyl-8-L-argininevasopressin. CAS No. 38106-69-3. Molecular formula: C48H67N15O13S2. Mole weight: 1126.28.
ACBC
ACBC. Group: Biochemicals. Grades: Purified. CAS No. 22264-50-2. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
ACBC
ACBC has been found to be a NMDA receptor partial agonist and could probably affect the signal transmission in the CNS. Synonyms: 1-Aminocyclobutane-1-carboxylic acid. Grades: ≥98% by HPLC. CAS No. 22264-50-2. Molecular formula: C5H9NO2. Mole weight: 115.13.
Synonyms: Ac-D-Ala(Cl)-Ome; Ac beta chloro D Ala Ome. CAS No. 327064-63-1. Molecular formula: C6H10ClNO3. Mole weight: 179.6.
ACBI1
ACBI1 is a potent PROTAC degrader of BAF ATPase subunits SMARCA2 and SMARCA4, also degrades the polybromo-associated BAF (PBAF) complex member PBRM1, with DC50s of 6 nM, 11 nM and 32 nM for SMARCA2, SMARCA4 and PBRM1 in MV-4-11 cells, respectively. ACBI1 is composed of a bromodomain ligand, a linker, and the E3 ubiquitin ligase VHL. ACBI1 can induce anti-proliferative effects and apoptosis. Synonyms: ACBI 1; ACBI-1; (2S,4R)-N-(2-(2-(4-((4-(3-amino-6-(2-hydroxyphenyl)pyridazin-4-yl)piperazin-1-yl)methyl)phenoxy)ethoxy)-4-(4-methylthiazol-5-yl)benzyl)-1-((S)-2-(1-fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide. CAS No. 2375564-55-7. Molecular formula: C49H58FN9O7S. Mole weight: 936.12.
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme about >80% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. TGC↑GCA ACG↓CGT. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer W. Storage: -20°C. Form: Liquid. Source: Acinetobacter calcoaceticus 16. Pack: 10 mM Tris-HCl (pH 7.5); 200 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: RE-1003EN.
Cell-permeable. A potent and selective inhibitor of ACC2 (Acetyl-CoA Carboxylase) (IC50 = 28nM for hACC2 vs 210nM for hACC1 in in vitro studies). Group: Biochemicals. Alternative Names: N-(1-(2-(4-Isopropoxyphenoxy)-2,5-bithiazol-5-yl)ethyl)acetamide. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Acc36 I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 3-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 100U; 500U. ACCTGC(N)4↑ TGGACG(N)8&darr. Activity: 2000-5000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: Acinetobacter calcoaceticus 36. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 100 μg/ml BSA; 50% glycerol. Cat No: RE-1004EN.
Acc65 I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA(dcm-) in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. G↑GTACC CCATG↓G. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer W. Storage: -20°C. Form: Liquid. Source: Acinetobacter calcoaceticus 65. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: RE-1005EN.
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme 95% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 500U; 2500U. G↑GYRCC CCRYG↓G. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer K, BSA. Storage: -20°C. Form: Liquid. Source: Acinetobacter calcoaceticus B1. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: RE-1006EN.
AccB7 I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA (dcm-) in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme 95% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. CCANNNN↑NTGG GGTN↓NNNNACC. Appearance: 10 X SE-buffer G. Storage: -20°C. Form: Liquid. Source: Acinetobacter calcoaceticus B7. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: RE-1007EN.
AccBS I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme 90% of dna fragments can be ligated. of these 50% can be recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. GAG↑CGG CTC↓GCC. Activity: 10000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: Acinetobacter calcoaceticus BS. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: RE-1008EN.
Accelerator ( MBTS )
Heterocyclic Organic Compound. CAS No. 120-78-4. Catalog: ACM120784.
Ac-CoA Synthase Inhibitor 1
Ac-CoA Synthase Inhibitor 1 is an anti-virus agent. Synonyms: 1-(2,3-Di(thiophen-2-yl)quinoxalin-6-yl)-3-(2-methoxyethyl)urea. Grades: ≥95%. CAS No. 508186-14-9. Molecular formula: C20H18N4O2S2. Mole weight: 410.51.
Ac-Cys(Farnesyl)-OH
Ac-Cys(Farnesyl)-OH. CAS No: 135304-07-3
Sarchem Laboratories New Jersey NJ
Ac-D-2-nal-D-4-clphe-D-3-pal
Heterocyclic Organic Compound. Alternative Names: AC-D-2-NAL-D-4-CLPHE-D-3-PAL. CAS No. 129225-22-5. Molecular formula: C32H31ClN4O5. Mole weight: 587.07. Catalog: ACM129225225.
Ac-D-a-indanylglycine
Ac-D-a-indanylglycine. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 5g. US Biological Life Sciences.
Ac-dC-Me Phosphonamidite, an esteemed chemical compound employed in the biochemical industry, enables the modification and synthesis of DNA, augmenting its utility. Its prominent utility is distinguished by the introduction of the methyl group, targeting the 5th position within the cytosine base of DNA, ultimately giving rise to a diverse spectrum of gene expression alterations and therapeutic benefits, which hold substantial potential in the field of disease management, particularly in cancer. Synonyms: 5'-Dimethoxytrityl-N4-acetyl-2'-deoxyCytidine, 3'-[(methyl)-(N,N-diisopropyl)]-phosphonamidite; N-Acetyl-3'-O-[methyl(diisopropylamino)phosphino]-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine. Molecular formula: C39H49N4O7P. Mole weight: 716.81.
Ac-dC-Me Phosphoramidite
AC-dC-Me Phosphoramidite is an indispensable instrument within the realm of biomedical research, finding its purpose in the intricate art of DNA strand modification and enhancement. Synonyms: 5'-Dimethoxytrityl-N-acetyl-2'-deoxyCytidine, 3'-[methyl-(N,N-diisopropyl)]-phosphoramidite. CAS No. 833480-37-8. Molecular formula: C39H49N4O8P. Mole weight: 732.81.
Ac-dC-PACE Phosphoramidite
Ac-dC-PACE Phosphoramidite, a vital instrument in the construction of oligonucleotides for eradicating viral infections and cancer, operates as a foundation for modified nucleic acid analogs, which specialize in pinpointing particular RNA or DNA sequences within the body. With its distinctive chemical makeup, it has the ability to stifle the spread of viruses and impede the progression of tumors, rendering it an auspicious nomination within the realm of biomedicine. Synonyms: 5'-Dimethoxytrityl-N-acetyl-2'-deoxyCytidine, 3'-O-(N,N-diisopropylamino)-phosphinyl-1,1-dimethyl-2-cyanoethyl acetate; N-Acetyl-5'-O- (4, 4'-dimethoxytrityl) -3'-O-[ (bisisopropylamino) (2-cyano-1, 1-dimethylethoxycarbonylmethyl) phosphino]-2'-deoxycytidine. Molecular formula: C45H56N5O9P. Mole weight: 841.93.
Ac-DEVD-AFC
Ac-DEVD-AFC is a fluorogenic substrate for caspase-3 and related caspases. Caspase activity can be quantified by fluorescent detection of free AFC (7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm. Synonyms: Ac-DEVD-7-amido-4-trifluoroMethylcoumarin; Caspase-3 Substrate ?, Fluorogenic; Ac-Asp-Glu-Val-Asp-AFC; N-acetyl-L-α-aspartyl-L-α-glutamyl-L-valyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine. Grades: ≥90%. CAS No. 201608-14-2. Molecular formula: C30H34F3N5O13. Mole weight: 729.61.
Ac-DEVD-AFC
Ac-DEVD-AFC is a fluorogenic substrate (λ ex =400 nm, λ em =530 nm). Uses: Scientific research. Group: Peptides. CAS No. 201608-14-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1005.
Ac-DEVD-AMC
Ac-DEVD-AMC is a fluorogenic substrate for caspase-3. Caspase activity can be quantified by fluorescent detection of free AMC (7-amino-4-methylcoumarin), which is excited at 340-360 nm and emits at 440-460 nm. Synonyms: N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-Methylcoumarin; N-acetyl-L-α-aspartyl-L-α-glutamyl-L-valyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine. Grades: ≥95%. CAS No. 169332-61-0. Molecular formula: C30H37N5O13. Mole weight: 675.64.
Ac-DEVD-CHO
Ac-DEVD-CHO is a specific Caspase-3 inhibitor with a K i value of 230 pM. Uses: Scientific research. Group: Peptides. CAS No. 169332-60-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P1001.
Ac-DEVD-CHO
Ac-DEVD-CHO is a potent aldehyde inhibitor of Group II caspases with Ki values of 0.2 nM and 0.3 nM for for caspase-3 and caspase-7, respectively. Weak inhibition for caspase-2. Uses: Cysteine proteinase inhibitors. Synonyms: N-acetyl-asp-glu-val-asp-al; Ac-Asp-Glu-Val-Asp-Aldehyde; L-Valinamide,N-acetyl-L-a-aspartyl-L-a-glutamyl-N-(2-carboxy-1-formylethyl)-. Grades: 95 %. CAS No. 169332-60-9. Molecular formula: C20H30N4O11. Mole weight: 502.47.
Ac-DEVD-CHO acetate
Ac-DEVD-CHO acetate is a specific inhibitor of Caspase-3. Synonyms: Caspase-3 Inhibitor I; N-acetyl-asp-glu-val-asp-al acetate; Ac-Asp-Glu-Val-Asp-al acetate; Ac-DEVD-al.CH3CO2H; L 761191 acetate; MF 191 acetate; N-acetyl-L-alpha-aspartyl-L-alpha-glutamyl-L-valyl-L-aspart-1-al acetate; N-Acetyl-L-α-aspartyl-L-α-glutamyl-N-[(1S)-2-carboxy-1-formylethyl]-L-valinamide acetate. Grades: ≥95%. Molecular formula: C22H34N4O13. Mole weight: 562.52.
Ac-DEVD-CMK
Ac-DEVD-CMK is a cell-permeable, and irreversible inhibitor of caspase-3 as well as caspase-6, -7, -8, and -10. It is commonly used at concentrations up to 100 μM to examine the role of caspase-3-dependent apoptosis in biological systems. Synonyms: Ac-Asp-Glu-Val-Asp-chloromethylketone; Caspase-3 Inhibitor III; N-acetyl-Asp-Glu-Val-Asp-chloromethylketone; N-Acetyl-L-α-aspartyl-L-α-glutamyl-N-[(2S)-1-carboxy-4-chloro-3-oxo-2-butanyl]-L-valinamide; (2S,5S,8S,11S)-8-(2-carboxyethyl)-11-(carboxymethyl)-2-(2-chloroacetyl)-5-isopropyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazatetradecane-1-carboxylic acid. Grades: ≥98%. CAS No. 285570-60-7. Molecular formula: C21H31ClN4O11. Mole weight: 550.95.
Ac-DEVD-pNA
Ac-DEVD-pNA is a colorimetric substrate for caspase-3 (CPP32) (Km=9.7μM) and related cysteine proteases. Synonyms: Ac-DL-Asp-DL-Glu-DL-Val-DL-Asp-pNA; DEVD; 4-[(2-acetamido-3-carboxypropanoyl)amino]-5-[[1-[[3-carboxy-1-(4-nitroanilino)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-oxopentanoic acid; NAc-Asp-Glu-Val-Asp-pNA. CAS No. 189950-66-1. Molecular formula: C26H34N6O13. Mole weight: 638.58.
Ac-dG Phosphoramidite
Cas No. 2417251-95-5. Molecular formula: C42H50N7O8P. Mole weight: 811.88.
Acetylleucine is a drug mianly used to treat the vertigo.It has been listed. Uses: Acetylleucine is used to treat the vertigo. Synonyms: Acetylleucine;N-Acetyl-DL-leucine;DL-Leucine,N-acetyl-;Acetyl-DL-leucine;Tanganil;2-Acetamido-4-methylpentanoic acid. Grades: >98 %. CAS No. 99-15-0. Molecular formula: C8H15NO3. Mole weight: 173.21.
Ac-DMQD-CHO is a peptide inhibitor of caspase-3 (IC50 = 39 nM). It is selective for caspase-3 over caspase-1 and caspase-8 (IC50s = 148 and 1,100 nM, respectively). Ac-DMQD-CHO inhibits apoptosis induced by camptothecin in immortalized human T/C 28a4 chondrocytes and primary human chondrocytes. In vivo, Ac-DMQD-CHO (1 mg/kg, i.v.) reduces the number of apoptotic cells, cavitation, and demyelination in a rat model of traumatic injury to the spinal cord. Synonyms: Ac-Asp-Met-Gln-Asp-CHO; Caspase-3 Inhibitor. Grades: ≥95%. Molecular formula: C20H31N5O10S·xCF3COOH. Mole weight: 533.6.
Ac-DNLD-AMC
Ac-DNLD-AMC is a fluorogenic substrate for caspase-3. It is cleaved by caspase-3 to release the fluorescent moiety 7-amino-4-methylcoumarin (AMC), which can be used to quantify caspase-3 activity. Synonyms: N-Acetyl-Asp-Asn-Leu-Asp-7-amido-Methylcoumarin; N-acetyl-L-α-aspartyl-L-asparaginyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine. Grades: ≥95%. CAS No. 958001-92-8. Molecular formula: C30H38N6O12. Mole weight: 674.7.
Ac-D-phenylglycinol 99+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g. US Biological Life Sciences.
Worldwide
ACDPP
ACDPP is a specific mGluR5 antagonist. ACDPP partially bolcks the increase of fragile X mental retardation protein (FMRP) caused by DHPG (HY-12598A) (group I mGluR Agonist) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 37804-11-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-103564.
ACDPP hydrochloride
ACDPP hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 37804-11-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
ACDPP hydrochloride
The hydrochloride salt form of ACDPP, which has been found to be a mGluR-5 antagonist. Synonyms: 3-Amino-6-chloro-5-dimethylamino-N-2-pyridinylpyrazinecarboxamide hydrochloride. Grades: ≥99% by HPLC. CAS No. 37804-11-8. Molecular formula: C12H13ClN6O.HCl. Mole weight: 329.19.