A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the suppliers website for prices or more information.
| Product | Description | |
|---|---|---|
| AM-001 | AM-001 is a non-competitive inhibitor of Epac1 that blocks the activation of Rap1, a downstream effector of Epac1, in cultured cells. AM-001 can be used in heart disease-related research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 340817-81-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-126133. |  |
| AM-0466 | AM-0466 is a potent and selective Nav1.7 inhibitor (IC50 = 0.020 nM). It exhibited an effective activity in a NaV1.7-dependent model of histamine-induced pruritus (itch) and also in a capsaicin-induced nociception model of pain. Synonyms: AM 0466; AM0466. CAS No. 1642113-59-4. Molecular formula: C27H19F3N4O4S. Mole weight: 552.52. |  |
| AM-0687 | This active molecular is a selective PI3Kδ inhibitor. PI3Kδ is hyperactivated in B-cell malignancies and plays a vital role in the B-cell receptor pathway. AM-0687 has Cellular potency: pAKT IC50 = 0.7 nM; HWB, u (pAKT) IC 50 = 4.6 nM. AM-0687 shows excellent potency and selectivity profile in biochemical and cellular assays. Uses: Cancer drug candidate. Synonyms: AM-0687; AM 0687; AM0687. 2 - ((1S) - 1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-6-fluoro - N - methyl-3-(2-pyridinyl)-4-quinolinecarboxamide. Grades: 98%. CAS No. 1259522-94-5. Molecular formula: C23H19FN8O. Mole weight: 442.46. | |
| AM 0902 | AM 0902 is an effective and selective TRPA1 antagonist and has been found to exhibit activities in biological pathways associated with pain. Synonyms: AM-0902; AM 0902; AM0902. 1-[[3-[2-(4-Chlorophenyl)ethyl]-1,2,4-oxadiazol-5-yl]methyl]-1,7-dihydro-7-methyl-6H-purin-6-one. Grades: ≥98% by HPLC. CAS No. 1883711-97-4. Molecular formula: C17H15ClN6O2. Mole weight: 370.79. | |
| AM095 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| AM095 | AM095, an effective LPA1 receptor antagonist, has been found to decrease dermal fibrosis caused by attenuates bleomycin. IC50: 0.98 uM and 0.73 uM for human and mouse LPA1 respectively. Synonyms: AM095 (free acid); AM-095; AM 095. Grades: 98%. CAS No. 1228690-36-5. Molecular formula: C27H24N2O5. Mole weight: 456.49. | |
| AM095 | AM095 is a selective LPA 1 receptor antagonist. The IC 50 for AM095 antagonism of LPA-induced calcium flux of human or mouse LPA 1 -transfected CHO cells is 0.025 and 0.023 μM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1345614-59-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-16039. | |
| AM095 free acid | AM095 (free acid) is a potent LPA1 receptor antagonist with IC 50 values of 0.98 and 0.73 μM for recombinant human or mouse LPA1 respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1228690-36-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-16040. | |
| AM095 sodium | AM095 is a selective LPA1 receptor antagonist. The IC50 for AM095 antagonism of LPA-induced calcium flux of human or mouse LPA1-transfected CHO cells is 0.025 and 0.023 μM, respectively. Synonyms: AM-095 sodium; AM 095 sodium. Grades: >98%. CAS No. 1345614-59-6. Molecular formula: C27H23N2NaO5. Mole weight: 478.48. | |
| AM103 | AM 103 is a potent and selective FLAP inhibitor, with an IC 50 value of 4.2 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1147872-22-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14163. | |
| AM-114 | AM 114 is an inhibitor of chymotrypsin-like activity of the 20S proteasome. In addition, AM-114 shows anticancer activity, It can inhibit cell growth in human colon cancer HCT116 p53+/+ cells. Uses: Anticancer. Synonyms: AM-114; AM 114; AM114; Proteasome Inhibitor IX; ( (1Z, 1'Z)- (1-methyl-4-oxopiperidine-3, 5-diylidene)bis (methanylylidene))bis (4, 1-phenylene))diboronic acid. Grades: 98%. CAS No. 856849-35-9. Molecular formula: C20H21B2NO5. Mole weight: 377.01. | |
| AM 1172 | AM 1172, an AEA analogue, has been found to be an anandamide uptake inhibitor as well as a cannabinoid receptor partial agonist. Synonyms: AM 1172; AM1172; AM-1172; N-(5Z,8Z,11Z,14Z)-5,8,11,14-eicosatetraen-1-yl-4-hydroxybenzamide. Grades: ≥98% by HPLC. CAS No. 251908-92-6. Molecular formula: C27H39NO2. Mole weight: 409.60. | |
| AM 1172 | AM 1172. Group: Biochemicals. Grades: Purified. CAS No. 251908-92-6. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| AM 12 | AM 12 is a TRPC5 inhibitor with an IC50 value of 0.28 μM, which exhibits some selectivity for TRPC5 over TRPC2, 3 and 4. Synonyms: 2-(2-Bromophenyl)-3,5,7-trihydroxy-4H-chromen-4-one. Grades: ≥97%. Molecular formula: C15H9BrO5. Mole weight: 349.14. | |
| AM1241 | AM-1241 is a selective cannabinoid CB2 receptor agonist with Ki of 3.4 nM, exhibits 82-fold selectivity over CB1 receptor. Synonyms: AM 1241; AM-1241; (1-(Methylpiperidin-2-ylmethyl)-3-(2-iodo-5-nitrobenzoyl)indole); (R,S)-3-(2-Iodo-5-nitrobenzoyl)-1-(1-methyl-2-piperidinylmethyl)-1H-indole. Grades: >98%. CAS No. 444912-48-5. Molecular formula: C22H22IN3O3. Mole weight: 503.33. | |
| AM-156 | Prostanoid GD(2) is released from mast cells in response to allergen challenge. AM156 is a selective prostanoid DP(2) receptor antagonist and it inhibits sneezing and nasal rubs in a model of allergic rhinitis. It can also inhibits pulmonary inflammation and mucus hypersecretion induced by chronic inhalation of house dust mite. AM156 may be have beneficial effects for treatment of allergic rhinitis and asthma in the future. Uses: Allergic rhinitis and asthma. Synonyms: AM-156; AM 156; AM156; UNII-5V9HJQ1Y75;sodium 2-(2'-((N-ethylcyclopropanecarboxamido)methyl)-6-methoxy-4'-(trifluoromethyl)-[1,1'-biphenyl]-3-yl)acetate;1175525-98-0 (AM-156 free acid). Grades: 98%. CAS No. 1224977-85-8. Molecular formula: C23H23F3NNaO4. Mole weight: 457.42. | |
| AM-156 sodium | AM-156 is a bio-active chemical and detailed information has not been published yet. Synonyms: AM-156 sodium; AM 156 sodium; AM156 sodium; sodium 2-(2'-((N-ethylcyclopropanecarboxamido)methyl)-6-methoxy-4'-(trifluoromethyl)-[1,1'-biphenyl]-3-yl)acetate,UNII-5V9HJQ1Y75,1175525-98-0 (AM-156 free acid). Grades: 98%. CAS No. 1175525-98-0. Molecular formula: C23H23F3NNaO4. Mole weight: 457.42. | |
| AM 1714 | AM 1714, a synthetic cannabimimetic indole derivative, is a potent and selective agonist for the cannabinoid receptor. Uses: A potent and selective agonist for the cannabinoid receptor. Synonyms: AM-1714; AM 1714; AM1714; UNII-E3OY6PCU04; 6H-Dibenzo(b,d)pyran-6-one, 3-(1,1-dimethylheptyl)-1,9-dihydroxy-. Grades: ≥98%. CAS No. 335371-37-4. Molecular formula: C22H26O4. Mole weight: 354.44. | |
| AM-206 | AM-206 is a bio-active chemical but no detailed data has been published yet. Synonyms: AM-206; AM 206; AM206; 3-Pyridineacetic acid, 5- (2- ( (ethyl ( (phenylmethoxy) carbonyl) amino) methyl) -4- (trifluoromethyl) phenyl) -, sodium salt (1:1); UNII-NCZ7ZWF0CR;1219935-54-2 (AM-206 free acid). Grades: 98%. CAS No. 1224977-86-9. Molecular formula: C25H22F3N2NaO4. Mole weight: 494.44. | |
| AM-206 sodium | AM-206 is a bio-active chemical but no detailed data has been published yet. Synonyms: AM-206; AM 206; AM206; UNII-NCZ7ZWF0CR;(5-(2-((N-((Benzyl)oxycarbonyl)-N-ethylamino)methyl)-4-trifluoromethylphenyl)pyridin-3-yl)acetic acid. Grades: 98%. CAS No. 1219935-54-2. Molecular formula: C25H23F3N2O4. Mole weight: 472.46. | |
| AM-2099 | AM-2099 is a potent and selective inhibitor of voltage-gated sodium channel Nav1.7 (IC50 = 0.16 μM) with excellent selectivity against hNav1.5 (IC50 > 30 uM). Synonyms: 4-[2-methoxy-4-(trifluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)quinazoline-7-sulfonamide; AM-2099; AM2099; AM 2099. CAS No. 1443373-17-8. Molecular formula: C19H13F3N4O3S2. Mole weight: 466.46. | |
| AM-211 | This active molecular is a potent Prostaglandin D2 receptor antagonists and has been in phase I clinical trials for both COPD (chronic obstructive pulmonary disease) and asthma, but no recent results has been published. Uses: Chronic obstructive pulmonary disease(copd) and asthma. Synonyms: AM-211; AM 211; AM211; 2-(2'-((3-benzyl-1-ethylureido)methyl)-6-methoxy-4'-(trifluoromethyl)-[1,1'-biphenyl]-3-yl)acetic acid,1263077-74-2 (AM-211 sodium). Grades: 98%. CAS No. 1175526-27-8. Molecular formula: C27H27F3N2O4. Mole weight: 500.51. | |
| AM-211 sodium | This active molecular is a potent Prostaglandin D2 receptor antagonists and has been in phase I clinical trials for both COPD (chronic obstructive pulmonary disease) and asthma, but no recent results has been published. Uses: Chronic obstructive pulmonary disease(copd) and asthma. Synonyms: UNII-8SV621U288;1175526-27-8(Free acid); AM-211 sodium; AM 211 sodium; AM211 sodium. Grades: 98%. CAS No. 1263077-74-2. Molecular formula: C27H26F3N2O4Na. Mole weight: 522.50. | |
| AM-2159 | AM-2159 is a bio-active chemical, but no detailed information has been published yet. Synonyms: AM-2159; AM 2159; AM2159; N6-((4-chlorophenyl)methyl)-N6-methyl- 2,4,6-Quinazolinetriamine. Grades: 98%. CAS No. 83654-06-2. Molecular formula: C16H16ClN5. Mole weight: 313.78. | |
| AM-2201 4-Hydroxypentyl metabolite-D5 (indole-D5) solution | 100 ?g/mL in methanol, ampule of 1 mL, certified reference material. Group: Cannabinoids standards. | |
| AM2201 4-Hydroxypentyl metabolite solution | 100 ?g/mL in methanol, ampule of 1 mL, certified reference material. Group: Certified reference materials (crms). | |
| AM-2233 | AM-2233. Group: Biochemicals. Alternative Names: (2-Iodophenyl)[1-[(1-methyl-2-piperidinyl)methyl]-1H-indol-3-yl]methanone; 1-[(N-Methyl-2-piperidinyl)methyl]-3-(2-iodobenzoyl)-1H-indole. Grades: Highly Purified. CAS No. 444912-75-8. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C22H23IN2O. US Biological Life Sciences. | Worldwide |
| AM-2394 | AM-2394 is a selective Glucokinase agonist (GKA), It activates GK with an EC50 value of 60 nM. AM-2394 increases the affinity of GK for glucose by approximately 10-fold. It shows moderate clearance and good oral bioavailability in animal models, and lowers glucose excursion following an oral glucose tolerance test in an ob/ob mouse model of diabetes. Uses: Diabetes. Synonyms: AM-2394; AM 2394; AM2394; 1-(6'-(2-hydroxy-2-methylpropoxy)-4-((5-methylpyridin-3-yl)oxy)-[3,3'-bipyridin]-6-yl)-3-methylurea. Grades: 98%. CAS No. 1442684-77-6. Molecular formula: C22H25N5O4. Mole weight: 423.47. | |
| AM251 | AM251 block the inhibitory effects of endocannabinoids and synthetic cannabinoid agonists on transmitter release through an action at presynaptic cannabinoid 1 receptors in brain. Synonyms: AM251; AM 251; AM-251. Grades: >98%. CAS No. 183232-66-8. Molecular formula: C22H21Cl2IN4O. Mole weight: 555.24. | |
| AM251 | >98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| AM251 | AM251 is a selective cannabinoid 1 ( CB1 ) receptor antagonist with an IC 50 of 8 nM. AM251 also acts as a potent GPR55 agonist with an EC 50 of 39 nM [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 183232-66-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15443. | |
| AM 251 | Inhibitor of CB1 receptors. Group: Biochemicals. Alternative Names: 1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide. Grades: Highly Purified. CAS No. 183232-66-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| AM281 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| AM281 | AM281 is a selective CB1 receptor antagonist with an IC 50 of 9.91 nM. AM281 inhibits CB2 receptor with an IC 50 of 13000 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 202463-68-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13505. | |
| AM 281 | AM 281 has been found to be a CB1 selective receptor cannabinoid antagonist. Synonyms: AM281; AM 281; AM-281; 1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-4-morpholinyl-1H-pyrazole-3-carboxamide. Grades: ≥99% by HPLC. CAS No. 202463-68-1. Molecular formula: C21H19Cl2IN4O2. Mole weight: 557.22. | |
| AM 281 | AM 281. Group: Biochemicals. Alternative Names: 1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-4-morpholinyl-1H-pyrazole-3-carboxamide. Grades: Highly Purified. CAS No. 202463-68-1. Pack Sizes: 1mg. Molecular Formula: C21H19Cl2IN4O2, Molecular Weight: 557.21. US Biological Life Sciences. | Worldwide |
| Am3102 | Am3102. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AM3102;(Z)-(R)-N-((2-Hydroxy-1-methyl)ethyl)-9-octadecenamide. Product Category: Heterocyclic Organic Compound. Appearance: A crystalline solid. CAS No. 213182-22-0. Molecular formula: C21H41NO2. Mole weight: 339.56. Density: 0.911. Product ID: ACM213182220. Alfa Chemistry ISO 9001:2015 Certified. Categories: AM302. |  |
| AM3102 | AM-3102 is an Oleoyl ethanolamide (OEA) analog that stimulates PPARα transcriptional activity with an EC50 value of 100 nM and prolongs feeding latency. The biological effects of OEA are terminated by N-acylethanolamine-hydrolyzing acid amidase and fatty-acid amide hydrolase. AM3102 demonstrates weak affinity for the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors with Ki values of 33 and 26 μM, respectively. Synonyms: KDS-5104; AM-3102; AM 3102; Methyl oleoylethanolamide. Grades: ≥98%. CAS No. 213182-22-0. Molecular formula: C21H41NO2. Mole weight: 339.6. | |
| AM3102 | AM3102 is an oleoylethanolamide (OEA) analog. AM3102 is an endogenous high-affinity PPAR-alpha agonist. AM3102 resists enzymatic hydrolysis, activates PPAR-alpha with high potency in vitro, and persistently reduces feeding when administered in vivo either parenterally or orally [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 213182-22-0. Pack Sizes: 5 mg. Product ID: HY-129683. | |
| AM-36 | AM-36 is a potent blocker of batrachotoxinin (BTX)-sensitive Na+ channel binding in rat brain homogenates with an IC50 of 0.28 microM. As a unique neuroprotective agent with anti-oxidant activity, in neuronal cell cultures, AM-36 inhibited toxicity induced by N-methyl-D-aspartate (NMDA) and the sodium channel opener veratridine and, in addition, inhibited veratridine-induced apoptosis. Synonyms: 2,6-ditert-butyl-4-[[4-[2-(4-chlorophenyl)-2-hydroxyethyl]piperazin-1-yl]methyl]phenol; AM-36; AM 36; AM36; UNII-08OBY024NY; SCHEMBL12311270; CNSB 002; CNSB-002; CNSB002. Grades: >98%. CAS No. 199467-52-2. Molecular formula: C27H39ClN2O2. Mole weight: 459.06. | |
| AM 374 | AM 374 is an fatty acid amide hydrolase (FAAH) inhibitor. AM 374 inhibits amidase activity with an IC 50 value of 13 nM. AM 374 can be used for the research of neurological disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 86855-26-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-125967. | |
| AM404 | AM-404 is a selective inhibitor of the carrier-mediated transport of anandamide without affecting anandamide hydrolysis. AEM is also an analog of arachidonyl ethanolamide (AEA) which potentiates the activity of endogenous AEA by blocking its reuptake into presynaptic neurons. AM404 inhibits endocannabinoid cellular uptake, binds weakly to CB1 and CB2 cannabinoid receptors, and is formed by fatty acid amide hydrolase (FAAH) in vivo. Synonyms: 5,8,11,14-Eicosatetraenamide, N-(4-hydroxyphenyl)-, (5Z,8Z,11Z,14Z)-; (5Z,8Z,11Z,14Z)-N-(4-Hydroxyphenyl)-5,8,11,14-eicosatetraenamide; 5,8,11,14-Eicosatetraenamide, N-(4-hydroxyphenyl)-, (all-Z)-; AM 404; AM404. Grades: ≥98%. CAS No. 183718-77-6. Molecular formula: C26H37NO2. Mole weight: 395.58. | |
| AM 404 | AM 404. Group: Biochemicals. Grades: Purified. CAS No. 198022-70-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AM 404-d4 | It is a labeled metabolite of the well-known analgesic Paracetamol. Group: Biochemicals. Alternative Names: (5Z,8Z,11Z,14Z)-N-(4-Hydroxyphenyl-d4)-5,8,11,14-eicosatetraenamide; (all-Z)-N-(4-Hydroxyphenyl-d4)-5,8,11,14-eicosatetraenamide. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| AM 404 (in Tocrisolve 100) | AM 404 (in Tocrisolve 100). Group: Biochemicals. Grades: Purified. CAS No. 198022-70-7. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| AM4113 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| AM 4113 | AM4113 has been found to be a CB1 antagonist and could be used in studies of some neuronal dendritic abnormalities diseases. Synonyms: AM 4113; AM-4113; AM4113; 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide. Grades: ≥98% by HPLC. CAS No. 614726-85-1. Molecular formula: C17H12Cl3N3O. Mole weight: 380.66. | |
| AM 4299 A | AM 4299 A is a thiol protease inhibitor produced by Chromelosporium fulvum M4299. Synonyms: Oxiranecarboxylic acid, 3-(((1-(((5-hydroxypentyl)amino)carbonyl)-3-methylbutyl)amino)carbonyl)-. Grades: >98%. CAS No. 160825-48-9. Molecular formula: C15H26N2O6. Mole weight: 330.38. | |
| AM 4299 B | AM 4299 B is a thiol protease inhibitor produced by Chromelosporium fulvum M4299. Synonyms: N(sup 6)-(N-((3-Carboxyoxiranyl)carbonyl)-L-leucyl)-L-lysine hydrate. Grades: >98%. CAS No. 160825-49-0. Molecular formula: C16H27N3O7. Mole weight: 373.40. | |
| AM4668 | AM4668 is a potent and selective G-protein coupled receptor 40(GPR40) agonist with EC50 value of 3.6 nM in an IP3 assay in GPR40 transfected A9 cells. It is more potent than AMG 837 and possesses excellent pharmacokinetic properties across species. It could reduce the plasma glucose levels in an OGTT study in human GPR40 knock-in mice. It inhibits insulin secretion from isolated pancreatic islets. Uses: Am4668 could reduce the plasma glucose levels in an ogtt study. it inhibits insulin secretion from isolated pancreatic islets. Synonyms: AM-4668; AM 4668; AM4668 ;(S)-3-(isoxazol-3-yl)-3-(4-((4-methyl-2-(4-(trifluoromethyl)phenyl)thiazol-5-yl)methoxy)phenyl)propanoic acid;(βS)-β-[4-[[4-Methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methoxy]phenyl)-3-isoxazolepropanoic acid. Grades: >98 %. CAS No. 1011531-27-3. Molecular formula: C24H19F3N2O4S. Mole weight: 488.48. | |
| AM580 | AM580 is a selective RARα agonist. It was shown to induce differentiation of human induced pluripotent stem cells into intermediate mesoderm. Synonyms: AM-580; 4-[(5,5,8,8-tetramethyl-6,7-dihydronaphthalene-2-carbonyl)amino]benzoic acid. Grades: >98%. CAS No. 102121-60-8. Molecular formula: C22H25NO3. Mole weight: 351.44. | |
| AM580 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| AM 580 | AM 580. Group: Biochemicals. Grades: Purified. CAS No. 102121-60-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AM 630 | AM 630. Group: Biochemicals. Alternative Names: [6-Iodo-2-methyl-1-[2- (4-morpholinyl) ethyl]-1H-indol-3-yl] (4-methoxyphenyl) methanone; Iodopravadoline. Grades: Highly Purified. CAS No. 164178-33-0. Pack Sizes: 5mg. Molecular Formula: C23H25IN2O3, Molecular Weight: 504.36. US Biological Life Sciences. | Worldwide |
| AM-643 | AM-643 is an active molecular. In the Biological Tests, it can inhibit FLAP in human whole blood assessed as inhibition of calcium ionophore A23187-induced LTB4 production preincubated for 5 hrs by ELISA and the activity value is 0.081μM. It can also Inhibit COX1-mediated TXB2 production in human whole blood after 30 mins by competitive enzyme immunoassay and the activity value is 25μM. Synonyms: AM-643 Free Acid; AM643 Free Acid; UNII-55668SZQ3E;3-(3-(tert-butylthio)-1-(4-(5-methoxypyrimidin-2-yl)benzyl)-5-((5-methylpyridin-2-yl)methoxy)-1H-indol-2-yl)-2,2-dimethylpropanoic acid. Grades: 98%. CAS No. 1233114-22-1. Molecular formula: C36H40N4O4S. Mole weight: 642.79. | |
| AM6545 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| AM6545 | AM6545 is a highly selective, brain-free (peripherally active) CB1 receptor antagonist ( K i =1.7 nM). AM6545 inhibits endocannabinoid signaling by competitively antagonizing CB1 receptors, inhibiting CB1-mediated appetite stimulation and inflammatory responses without affecting cAMP levels. AM6545 significantly reduces food intake and body weight in mice, while improving metabolic syndrome-related renal impairment (such as proteinuria, fibrosis) and insulin resistance. AM6545 can be used in the study of obesity and its complications [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1245626-05-4. Pack Sizes: 1 mg. Product ID: HY-110206. | |
| AM 6545 | AM 6545 has been found to be a CB1 antagonist and could probably be used as an appetite suppressant. Synonyms: AM 6545; AM6545; AM-6545; 5-[4-(4-Cyano-1-butyn-1-yl)phenyl]-1-(2,4-dichlorophenyl)-N-(1,1-dioxido-4-thiomorpholinyl)-4-methyl-1H-pyrazole-3-carboxamide. Grades: ≥98% by HPLC. CAS No. 1245626-05-4. Molecular formula: C26H23Cl2N5O3S. Mole weight: 556.46. | |
| AM679 | AM679 is a drug which acts as a selective inhibitor of 5-Lipoxygenase-activating protein (FLAP). This protein is involved in the production of cysteinyl leukotrienes which are involved in inflammation, and AM679 has anti-inflammatory effects in animal studies. AM679 also showed potent inhibition of leukotrienes in human blood and in a rodent bronchoalvelolar lavage (BAL) challenge model. Research showed AM679 reduces inflammation in the respiratory syncytial virus-infected mouse eye. Synonyms: AM-679; AM 679; AM679; UNII-65KJ8P7M9D; CHEMBL595092; SCHEMBL503239; 65KJ8P7M9D. Grades: >98%. CAS No. 1206880-66-1. Molecular formula: C40H44N4O5S. Mole weight: 692.87. | |
| AM-694 | A synthetic cannabimimetic indole derivative which acts as a potent and selective agonist for the cannabinoid receptor CB1. Group: Biochemicals. Alternative Names: [1-(5-Fluoropentyl)-1H-indol-3-yl](2-iodophenyl)methanone; AM694; 1-(5-Fluoropentyl)-3-(2-iodobenzoyl)indole. Grades: Highly Purified. CAS No. 335161-03-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| AM-694-d4 | The labeled analogue of a synthetic cannabimimetic indole derivative which acts as a potent and selective agonist for the cannabinoid receptor CB1. Group: Biochemicals. Alternative Names: [1-(5-Fluoropentyl)-1H-indol-3-yl](2-iodophenyl-d4)methanone; AM694-d4; 1-(5-Fluoropentyl)-3-(2-iodobenzoyl-d4)indole. Grades: Highly Purified. CAS No. 1346600-15-4. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| AM 80 | AM 80. Group: Biochemicals. Grades: Purified. CAS No. 94497-51-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AM-8508 | AM-8508 is a selective Phosphatidylinositol-3-kinase delta (PI3Kδ) inhibitor. AM-8508 exhibits good cellular potency (in vitro pAKT IC50 = 4.6 nM ) and excellent HWB potency (HWB (pAKT) IC50 = 2.7 nM). AM-8508 inhibits KLH-specific antibodies in animal models and it may become a drug candidate for the treatment of human inflammatory diseases. Uses: Inflammatory diseases. Synonyms: AM-8508; AM 8508; AM8508. (S)-4-amino-6-((1-(6-fluoro-1-(pyridin-3-yl)-1H-benzo[d]imidazol-2-yl)ethyl)amino)pyrimidine-5-carbonitrile. Grades: 98%. CAS No. 1338483-67-2. Molecular formula: C19H15FN8. Mole weight: 374.14. | |
| AM 92016 hydrochloride | The hydrochloride salt form of AM 92016, which has been found to be a specific blocker of the time dependent delayed rectifier potassium current and probably be useful in antiarrhythmic studies. Synonyms: Methanesulfonamide, N-[4-[3-[[2-(3,4-dichlorophenyl)ethyl]methylamino]-2-hydroxypropoxy]phenyl]-, hydrochloride (1:1); Methanesulfonamide, N-[4-[3-[[2-(3,4-dichlorophenyl)ethyl]methylamino]-2-hydroxypropoxy]phenyl]-, monohydrochloride; 1-(4-Methanesulfonamidophenoxy)-3-(n-methyl-3,4-dichlorophenylethylamino)-2-propanol hydrochloride. Grades: ≥98% by HPLC. CAS No. 133229-11-5. Molecular formula: C19H24Cl2N2O4S.HCl. Mole weight: 483.84. | |
| AM 92016 hydrochloride | AM 92016 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 133229-11-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| AM-9514 | AM-9514 is a glucokinase (GK) activator. It shows a favorable combination of in vitro potency, enzyme kinetic properties, acceptable pharmacokinetic profiles in preclinical species, and robust efficacy in a rodent PD model. Glucokinase is very important in regulating glucose homeostasis. AM-9514 may become a drug candidate for the treatment of type 2 diabetes. Uses: Type 2 diabetes. Synonyms: AM-9514; AM9514; AM 9514; 1-(3-((1-ethyl-1H-pyrazol-5-yl)oxy)-5-(((1r,3s)-3-hydroxy-3-methylcyclobutyl)methyl)pyridin-2-yl)-3-methylurea. Grades: 98%. CAS No. 1442677-18-0. Molecular formula: C18H25N5O3. Mole weight: 359.43. | |
| AM-9635 | AM-9635 is a selective Phosphatidylinositol-3-kinase delta (PI3Kδ) inhibitor. AM-9635 exhibits good cellular potency (in vitro pAKT IC50 = 4.2 nM ). AM-9635 can inhibit KLH-specific IgG and IgM in a dosedependent manner and it is well tolerated at all doses. AM-96352 shows significantly reduced IgG and IgM specific antibodies. Synonyms: AM-9635; AM 9635; AM9635. (S)-4-amino-6-((1-(6-fluoro-1-(5-fluoropyridin-3-yl)-1H-benzo[d]imidazol-2-yl)ethyl)amino)pyrimidine-5-carbonitrile. Grades: 98%. CAS No. 1338483-10-5. Molecular formula: C19H14F2N8. Mole weight: 392.36. | |
| AM 966 | AM966, a LPA1 receptor antagonist, has been found to restrain lung fibrosis in mouse model. IC50: 17 nM. Uses: Am966 is a lpa1 receptor antagonist that has been found to restrain lung fibrosis in mouse model. Synonyms: AM-966; AM 966; AM966; 2-[4-[4-[4-[[(1R)-1-(2-chlorophenyl)ethoxy]carbonylamino]-3-methyl-1,2-oxazol-5-yl]phenyl]phenyl]aceticacid;AM966;AM-966;UNII-CEO54NH393;1228690-19-4;(R)-2-(4'-(4-(((1-(2-Chlorophenyl)ethoxy)carbonyl)amino)-3-methylisoxazol-5-yl)-[1,1'-biphenyl]-4-yl)acet. Grades: 95%. CAS No. 1228690-19-4. Molecular formula: C27H23ClN2O5. Mole weight: 490.93. | |
| AMA-37 | AMA-37, an Arylmorpholine analog, is ATP-competitive DNA-PK inhibitor, with IC 50 values of 0.27 μM (DNA-PK), 32 μM (p110α), 3.7 μM (p110β), and 22 μM (p110γ), respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 404009-46-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100706. | |
| Ama87 I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. C↑YCGRG GRGCY↓C. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer W, BSA. Storage: -20°C. Form: Liquid. Source: Alteromonas macleodii 87. Pack: 10 mM KH2PO4 (pH 7.2); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 50% glycerol. Cat No: RE-1020EN. |  |
Our database is helping our users find suppliers everyday.
