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| Product | Description | |
|---|---|---|
| Alverine citrate | Alverine citrate is a 5-HT 1A receptor antagonist, with an IC 50 of 101 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC 35459. CAS No. 5560-59-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0500. |  |
| Alverine Citrate | Alverine Citrate is a highly potent competitive CXCR4 antagonist with EC50 of 0.3 nM. Uses: Parasympatholytics. Synonyms: N-ethyl-3-phenyl-N-(3-phenylpropyl)propan-1-amine; 2-hydroxypropane-1,2,3-tricarboxylic acid. Grade: > 98 %. CAS No. 5560-59-8. Molecular formula: C20H27N · C6H8O7. Mole weight: 473.56. |  |
| Alverine Citrate Impurity A | An impurity of Alverine Citrate. Synonyms: (3-Chloro-1-propyl)benzene, 3-Phenylpropyl chloride, Hydrocinnamyl chloride. Grade: > 95%. CAS No. 104-52-9. Molecular formula: C9H11Cl. Mole weight: 154.64. | |
| Alverine Citrate Impurity B | Alverine Citrate Impurity B is an impurity of Alverine Citrate, which is a highly potent competitive CXCR4 antagonist. It is a flavoring ingredient found in storax and fern balms, burdock fruits, guava fruit and peel, blackberries, rum, white wine, shiitake mushrooms, matsutake, and peat malt. Synonyms: Benzenepropanol; 1-Propanol, 3-phenyl-; (3-Hydroxypropyl)benzene; 1-Hydroxy-3-phenylpropane; 3-Benzenepropanol; 3-Hydroxy-1-phenylpropane; 3-Phenyl-1-propanol; 3-Phenyl-n-propanol; 3-Phenylpropanol; 3-Phenylpropyl alcohol; Dihydrocinnamic alcohol; Dihydrocinnamyl alcohol; Hydrocinnamic alcohol; Hydrocinnamyl alcohol; NSC 16942; γ-Phenylpropanol; γ-Phenylpropyl alcohol; Alverine EP Impurity B. Grade: ≥95%. CAS No. 122-97-4. Molecular formula: C9H12O. Mole weight: 136.19. | |
| Alverine Citrate Impurity C | An impurity of Alverine Citrate. Synonyms: N-Ethyl-3-phenylpropan-1-amine Hydrochloride. Grade: > 95%. CAS No. 13125-63-8. Molecular formula: C11H17N HCl. Mole weight: 163.26 36.46. | |
| Alverine Citrate Impurity E | An impurity of Alverine Citrate. Synonyms: Tris(3-phenylpropyl)amine HCl. Grade: > 95%. CAS No. 878784-75-9. Molecular formula: C27H33N HCl. Mole weight: 371.57 36.46. | |
| Alverine-[d5] Citrate | Alverine-[d5] Citrate is the labelled analogue of Alverine Citrate, which is an adrenergic-β3 receptor agonist used as a smooth muscle relaxant. Synonyms: Alverine D5 Citrate; N-(Ethyl-d5)-N-(3-phenylpropyl)benzenepropanamine 2-Hydroxy-1,2,3-propanetricarboxylate; N-(Ethyl-d5)-3,3'-diphenyldipropylamine Citrate; Antispasmin-d5; Calmabel-d5; Gamatran-d5; NSC 35459-d5; Profenine-d5; Prophelan-d5; Proverine-d5; Spacolin-d5; Spasmaverine-d5; Spasmonal-d5. Grade: >95%. CAS No. 1215327-00-6. Molecular formula: C20H22D5N.C6H8O7. Mole weight: 478.57. | |
| Alverine EP Impurity A | Alverine EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3-chloropropyl)benzene. CAS No. 104-52-9. Molecular formula: C9H11Cl. Mole weight: 154.64. Catalog: APB104529. |  |
| Alverine EP Impurity B | Alverine EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-phenylpropan-1-ol. CAS No. 122-97-4. Molecular formula: C9H12O. Mole weight: 136.19. Catalog: APB122974. | |
| Alvespimycin | Alvespimycin (17-DMAG; KOS-1022; NSC 707545) is a potent, water-soluble Hsp90 inhibitor with IC50 of 62 nM. 17-DMAG displays ~2 times potency against human Hsp90 than 17-AAG, with IC50 of 62 nM versus 119 nM. In SKBR3 and SKOV3 cells which overexpress Hsp90 client protein Her2, 17-DMAG causes down-regulation of Her2 with EC50 of 8 nM and 46 nM, respectively, as well as induction of Hsp70 with EC50 of 4 nM and 14 nM, respectively, leading to significant cytotoxicity with GI50 of 29 nM and 32 nM, respectively, consistent with Hsp90 inhibition. In combination with vorinostat, 17-DMAG synergistically induces apoptosis of the cultured MCL cells as well as primary MCL cells, more potently than either agent alone, by markedly attenuating the levels of cyclin D1 and CDK4, as well as of c-Myc, c-RAF and Akt. 17-DMAG treatment at 5 mg/kg or 25 mg/kg three times per week significantly reduces tumor growth of TMK-1 xenografts, by reducing vessel area and numbers of proliferating tumor cells in sections. Consistent the inhibition of FAK signaling in vivo, 17-DMAG treatment at 25 mg/kg three times a week significantly suppresses tumor growth, and metastasis of ME180 and SiHa xenografts in mice. Administration of 17-DMAG at 10 mg/kg for 16 days significantly decreases the white blood cell count and prolongs the survival in a TCL1-SCID transplant mouse model. Uses: Hsp-90 inhibitor; potential anti-cancer drug. Synonyms: 17-DMAG; KOS 1022; K | |
| Alvespimycin | Alvespimycin (17-DMAG) is a potent inhibitor of Hsp90 , binding to Hsp90 with an EC 50 of 62 ± 29 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 17-DMAG; KOS-1022; NSC 707545. CAS No. 467214-20-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10389. | |
| Alvespimycin hydrochloride | Alvespimycin hydrochloride (17-DMAG hydrochloride; KOS-1022; BMS 826476) is a potent inhibitor of Hsp90 , binding to Hsp90 with EC 50 of 62±29 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 17-DMAG hydrochloride; KOS-1022 hydrochloride; BMS 826476. CAS No. 467214-21-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 100 mg; 200 mg. Product ID: HY-12024. | |
| Alvimopan | Alvimopan (ADL 8-2698) is a potent, selective, orally active and reversible μ-opioid receptor antagonist, with an IC 50 of 1.7 nM. Alvimopan has selectivity for μ-opioid receptor ( K i =0.47 nM) over κ- and δ-opioid receptors ( K i s=100, 12 nM, respectively). Alvimopan can be used for the research of postoperative ileus [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ADL 8-2698; LY 246736. CAS No. 156053-89-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13243. | |
| Alvimopan | Alvimopan. Group: Biochemicals. Alternative Names: N-[(2S)-2-[[(3R,4R)-4-(3-Hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-1-oxo-3-phenylpropyl]glycine; ADL 8-2698; LY 246736. Grades: Highly Purified. CAS No. 156053-89-3. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C25H32N2O4. US Biological Life Sciences. |  Worldwide |
| Alvimopan | Alvimopan is a novel, oral, peripherally acting antagonist of the mu opioid receptor, which can help gastrointestinal recovery after surgery. Phase III IC50: Mu-type opioid receptor= 1.7 nM. Uses: A peripheral μ-opioid receptor antagonist. gastroprokinetic. Synonyms: 2-[[(2S)-2-benzyl-3-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]propanoyl]amino]acetic acid ADL 8-2698 ADL8-2698 alvimopan alvimopan anhydrous anhydrous alvimopan Entereg LY 246736 LY-246736 LY246736 trans-3,4-dimethyl-4-(3-hydroxyphenyl) pipe. Grade: ≥98%. CAS No. 156053-89-3. Molecular formula: C25H32N2O4. Mole weight: 424.53. | |
| Alvimopan | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Alvimopan Acyl Glucuronide (mixture of isomers) | A metabolite of Alvimopan. Synonyms: Alvimopan Acyl-β-D-glucuronide. Grade: > 95%. CAS No. 1260616-95-2. Molecular formula: C31H40N2O10. Mole weight: 600.67. | |
| Alvimopan-[d5] | Alvimopan-[d5] is the labelled analogue of Alvimopan. Alvimopan is a μ-opioid receptor antagonist with limited activity of μ-opioid receptor in the central nervous system. It is indicated for postoperative ileus. Synonyms: Alvimopan-d5; rac-N-[2-[[4-(3-Hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-1-oxo-3-(phenyl-d5)propyl]glycine; ADL 8-2698-d5; LY 246736-d5; Entereg-d5. Grade: >95%. CAS No. 1217616-62-0. Molecular formula: C25H27D5N2O4. Mole weight: 429.56. | |
| Alvimopan-d5 Metabolite | Labelled Alvimopan Metabolite. Alvimopan is a μ-opioid receptor antagonist with limited activity of μ-opioid receptor in the central nervous system. It is indicated for postoperative ileus. Synonyms: ADL 08-0011-d5. Grade: > 95%. Molecular formula: C23H24NO3D5. Mole weight: 372.52. | |
| Alvimopan-[d7] | Alvimopan-[d7] is the labelled analogue of Alvimopan. Alvimopan is a μ-opioid receptor antagonist with limited activity of μ-opioid receptor in the central nervous system. It is indicated for postoperative ileus. Synonyms: Alvimopan-d7; rac-N-[2-[[4-(3-Hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-1-oxo-3-(phenyl)propyl]glycine-d7; ADL 8-2698-d7; LY 246736-d7; Entereg-d7. Grade: 95% by HPLC; 98% atom D. CAS No. 1261396-48-8. Molecular formula: C25H25D7N2O4. Mole weight: 431.58. | |
| Alvimopan dihydrate | Alvimopan dihydrate is a novel, orally available peripherally restricted opioid antagonist with low systemic absorption. It accelerates the gastrointestinal recovery period with most common side effects in chronic pain patients with OBD were abdominal pai. Synonyms: 2-[[(2S)-2-benzyl-3-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]propanoyl]amino]acetic acid; dihydrate ADL 8-2698 ADL8-2698 alvimopan alvimopan anhydrous anhydrous alvimopan Entereg LY 246736 LY-246736 LY246736 trans-3,4-dimethyl-4-(3-hydroxyph. CAS No. 170098-38-1. Molecular formula: C25H32N2O4.2H2O. Mole weight: 460.57. | |
| Alvimopan Metabolite | A metabolite of Alvimopan. Synonyms: ADL 08-0011. Grade: > 95%. CAS No. 156130-41-5. Molecular formula: C23H29NO3. Mole weight: 367.49. | |
| Alvimopan monohydrate | The monohydrate salt form of Alvimopan could be commonly used in postoperative recovery of gastrointestinal for acting as a mu-opioid receptor (PAM-OR) antagonist with IC50: 1.7 nM. Uses: The monohydrate salt form of alvimopan could be commonly used in postoperative recovery of gastrointestinal for acting as a mu-opioid receptor (pam-or) antagonist. Synonyms: UNII-28LAR2REDG; 28LAR2REDG; DTXSID30160641; 3078AH; 2-[[(2S)-2-benzyl-3-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]propanoyl]amino]acetic acid; hydrate. Grade: 98%. CAS No. 1383577-62-5. Molecular formula: C25H34N2O5. Mole weight: 442.55. | |
| Alvocidib | Alvocidib is a synthetic N-methylpiperidinyl chlorophenyl flavone compound. As an inhibitor of cyclin-dependent kinase, alvocidib induces cell cycle arrest by preventing phosphorylation of cyclin-dependent kinases (CDKs) and by down-regulating cyclin D1 and D3 expression, resulting in G1 cell cycle arrest and apoptosis. Uses: For research used only. Synonyms: Flavopiridol; HMR 1275. HMR1275. HMR-1275. Grade: 0.98. CAS No. 146426-40-6. Molecular formula: C21H20ClNO5. Mole weight: 401.84. | |
| ALW-II-41-27 | ALW-II-41-27 is an effective inhibitor of EPH family kinases that has been found to be related to lung cancers. IC50: 11 nM to EPHA2. Uses: Alw-ii-41-27 is an effective inhibitor of eph family kinases that is found to be related to lung cancers. Synonyms: ALW-II-41-27; ALW II-41-27; ALWII-41-27; ALW-II-4127; ALW II-4127; ALWII-4127; MLS002232274; CHEMBL556140; DTXSID80655254; BDBM163701. Grade: 98%. CAS No. 1186206-79-0. Molecular formula: C32H32F3N5O2S. Mole weight: 607.69. | |
| ALW-II-41-27 | ALW-II-41-27 is a Eph family tyrosine kinase inhibitor with an IC50 of 11 nM for Eph2. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Eph receptor tyrosine kinase inhibitor. CAS No. 1186206-79-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18007. | |
| ALW-II-41-27 | ALW-II-41-27 is a Eph receptor tyrosine kinase inhibitor. pharmacologic inhibition of EPHA2 by the small-molecule inhibitor ALW-II-41-27 decreased both survival and proliferation of erlotinib-resistant tumor cells and inhibited tumor growth in vivo. ALW-II-41-27 was also effective in decreasing viability of cells with acquired resistance to the third-generation EGFR TKI AZD9291. Collectively, these data define a role for EPHA2 in the maintenance of cell survival of TKI-resistant, EGFR-mutant lung cancer and indicate that EPHA2 may serve as a useful therapeutic target in TKI-resistant tumors. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ALW-II-41-27; ALW II-41-27; ALWII-41-27; ALW-II-4127; ALW II-4127; ALWII-4127. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1186206-79-0. Molecular formula: C32H32F3N5O2S. Mole weight: 607.7. Purity: >98%. IUPACName: N-(5-((4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)carbamoyl)-2-methylphenyl)-5-(thiophen-2-yl)nicotinamide. Canonical SMILES: O=C(NC1=CC(C(NC2=CC=C(CN3CCN(CC)CC3)C(C(F)(F)F)=C2)=O)=CC=C1C)C4=CN=CC(C5=CC=CS5)=C4. Product ID: ACM1186206790. Alfa Chemistry ISO 9001:2015 Certified. |  |
| ALW-II-49-7 | ALW-II-49-7 is a selective EphB2 kinase inhibitor with an EC50 value of 40 nM in cell[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1135219-23-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18833. | |
| ALX-1393 | ALX-1393 is a selective glycine transporter GlyT2 inhibitor that has an antinociceptive effect on thermal, mechanical and chemical stimulation in rat models of acute pain. Synonyms: (2S)-2-amino-3-((2-(benzyloxy)phenyl)(3-fluorophenyl)methoxy)propanoic acid; O-[2-benzyloxyphenyl-3-flurophenyl]methyl-L-serine; L-Serine, O-[(3-fluorophenyl)[2-(phenylmethoxy)phenyl]methyl]-. Grade: ≥95%. CAS No. 949164-09-4. Molecular formula: C23H22FNO4. Mole weight: 395.42. | |
| ALX 40-4C | ALX 40-4C is a small peptide inhibitor of the chemokine receptor CXCR4, which inhibits the binding of SDF-1 to CXCR4 and inhibits the replication of X4 strain HIV-1. It is also an APJ receptor antagonist. Synonyms: Ac-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-NH2; N-acetyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-argininamide; Ac-(D-Arg)9-NH2; ALX40-4C; N-alpha-Acetyl-nona-D-arginine amide. Grade: ≥95%. CAS No. 143413-49-4. Molecular formula: C56H113N37O10. Mole weight: 1464.74. | |
| ALX 40-4C acetate | ALX 40-4C acetate is a small peptide inhibitor of the chemokine receptor CXCR4. It inhibits SDF-1 from binding CXCR4 with a Ki of 1 μM, and suppresses the replication of X4 strains of HIV-1. Molecular formula: C58H117N37O12. Mole weight: 1524.79. | |
| ALX 40-4C Trifluoroacetate | ALX 40-4C Trifluoroacetate is a small peptide inhibitor of the chemokine receptor CXCR4, which inhibits the binding of SDF-1 to CXCR4 and inhibits the replication of X4 strain HIV-1. It is also an APJ receptor antagonist. Synonyms: Ac-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-NH2.TFA; N-acetyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-argininamide trifluoroacetic acid; ALX 40-4C TFA. Grade: >98%. Molecular formula: C56H113N37O10.C2HF3O2. Mole weight: 1578.76. | |
| ALX 5407 hydrochloride | The hydrochloride salt form of ALX 5407, which has been found to be an inhibitor of the glycine transporter GlyT1 and could probably be useful in some neuropsychiatric disorders. Synonyms: ALX 5407 hydrochloride; ALX-5407 hydrochloride; ALX5407 hydrochloride; N-[(3R)-3-([1,1'-Biphenyl]-4-yloxy)-3-(4-fluorophenyl)propyl]-N-methylglycine hydrochloride. Grade: ≥98% by HPLC. CAS No. 200006-08-2. Molecular formula: C24H24FNO3.HCl. Mole weight: 429.92. | |
| ALX 5407 hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ALX 5407 hydrochloride | ALX 5407 hydrochloride. Group: Biochemicals. Alternative Names: N-[(3R)-3-([1,1'-Biphenyl]-4-yloxy)-3-(4-fluorophenyl)propyl]-N-methylglycine hydrochloride. Grades: Highly Purified. CAS No. 200006-08-2. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C24H25ClFNO3. US Biological Life Sciences. | Worldwide |
| ALX-5407 hydrochloride | ALX-5407 ((R)-NFPS) hydrochloride is a selective and orally active glycine transporter GlyT1 inhibitor with an IC 50 value of 3 nM. ALX-5407 hydrochloride can be used the research of N-methyl-D-aspartate-receptor function and schizophrenia [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-NFPS hydrochloride. CAS No. 200006-08-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-10711A. | |
| Alyssin | Alyssin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-ISOTHIOCYANATO-5-(METHYLSULFINYL)-PENTANE;ALYSSIN;ALYSSIN SULFONE;5-methylsulfinylpentylimino(thioxo)methane. Product Category: Heterocyclic Organic Compound. Appearance: liquid. CAS No. 646-23-1. Molecular formula: C7H13NOS2. Mole weight: 191.31. Purity: 0.96. IUPACName: 1-isothiocyanato-5-methylsulfinylpentane. Canonical SMILES: CS(=O)CCCCCN=C=S. Density: 1.14g/cm³. Product ID: ACM646231. Alfa Chemistry ISO 9001:2015 Certified. Categories: Alyssum. | |
| Alyteserin-1a | Alyteserin-1a is an antimicrobial peptide produced by Alytes obstetricans (European midwife toad). It has antibacterial activity against Gram-negative bacterium such as E. coli (MIC=25 μM). Synonyms: Gly-Leu-Lys-Asp-Ile-Phe-Lys-Ala-Gly-Leu-Gly-Ser-Leu-Val-Lys-Gly-Ile-Ala-Ala-His-Val-Ala-Asn-NH2. Grade: >96%. CAS No. 1159767-77-7. Molecular formula: C104H176N30O27. Mole weight: 2278.74. | |
| Alyteserin-1b | Alyteserin-1b is an antimicrobial peptide produced by Alytes obstetricans (European midwife toad). It has antibacterial activity against Gram-negative bacterium such as E. coli (MIC=25 μM). Synonyms: Gly-Leu-Lys-Glu-Ile-Phe-Lys-Ala-Gly-Leu-Gly-Ser-Leu-Val-Lys-Gly-Ile-Ala-Ala-His-Val-Ala-Asn-NH2. Grade: ≥97%. CAS No. 1159767-78-8. Molecular formula: C105H178N30O27. Mole weight: 2292.76. | |
| Alyteserin-1c | Alyteserin-1c is an antimicrobial peptide produced by Alytes obstetricans (European midwife toad). It has antibacterial activity against Gram-negative bacterium such as E. coli (MIC=25 μM). Synonyms: Gly-Leu-Lys-Glu-Ile-Phe-Lys-Ala-Gly-Leu-Gly-Ser-Leu-Val-Lys-Gly-Ile-Ala-Ala-His-Val-Ala-Ser-NH2. Grade: 98%. CAS No. 1159767-79-9. Molecular formula: C104H177N29O27. Mole weight: 2265.74. | |
| Alyteserin-1d | Alyteserin-1d is an antimicrobial peptide produced by Alytes obstetricans (European midwife toad). It has antibacterial activity. Synonyms: Gly-Leu-Lys-Asp-Ile-Phe-Lys-Ala-Gly-Leu-Gly-Ser-Leu-Val-Lys-Asn-Ile-Ala-Ala-His-Val-Ala-Asn-NH2. Grade: >98%. CAS No. 1159767-80-2. Molecular formula: C106H179N31O28. Mole weight: 2335.79. | |
| Alyteserin-1Ma | Alyteserin-1Ma is an antimicrobial peptide produced by Alytes maurus (Midwife toad). It has antibacterial and antifungal activity. It is active against Gram-negative bacterium: Escherichia coli NCTC 10418 (MIC=214 μM) and Gram-positive bacterium: Staphylococcus aureus NCTC 10788 (MIC=214 μM). Synonyms: Gly-Phe-Lys-Glu-Val-Leu-Lys-Ala-Asp-Leu-Gly-Ser-Leu-Val-Lys-Gly-Ile-Ala-Ala-His-Val-Ala-Asn-NH2. Grade: >98%. Molecular formula: C106H178N30O29. Mole weight: 2336.77. | |
| Alyteserin-1Mb | Alyteserin-1Mb is an antimicrobial peptide produced by Alytes maurus (Midwife toad). It has antibacterial and antifungal activity. It is active against Gram-negative bacterium: Escherichia coli NCTC 10418 (MIC=217 μM) and Gram-positive bacterium: Staphylococcus aureus NCTC 10788 (MIC=434 μM). Synonyms: Gly-Phe-Lys-Glu-Val-Leu-Lys-Ala-Gly-Leu-Gly-Ser-Leu-Val-Lys-Gly-Ile-Pro-Ala-His-Val-Ala-Asn-NH2. Grade: ≥97%. Molecular formula: C106H178N30O27. Mole weight: 2304.77. | |
| Alyteserin-2a | Alyteserin-2a is an antimicrobial peptide produced by Alytes obstetricans (European midwife toad). It has antibacterial activity against Gram-positive bacterium such as Staphylococcus aureus (MIC=50 μM). Synonyms: Ile-Leu-Gly-Lys-Leu-Leu-Ser-Thr-Ala-Ala-Gly-Leu-Leu-Ser-Asn-Leu-NH2. Grade: ≥96%. CAS No. 1159767-81-3. Molecular formula: C72H131N19O20. Mole weight: 1582.95. | |
| Alyteserin-2b | Alyteserin-2b is an antimicrobial peptide produced by Alytes obstetricans (European midwife toad). It has antibacterial activity. Synonyms: Ile-Leu-Gly-Ala-Ile-Leu-Pro-Leu-Val-Ser-Gly-Leu-Leu-Ser-Asn-Lys-Leu-NH2. Grade: >98%. CAS No. 1159767-82-4. Molecular formula: C81H146N20O20. Mole weight: 1720.18. | |
| Alyteserin-2c | Alyteserin-2c is an antimicrobial peptide produced by Alytes obstetricans (European midwife toad). It has antibacterial activity. Synonyms: Ile-Leu-Gly-Ala-Ile-Leu-Pro-Leu-Val-Ser-Gly-Leu-Leu-Ser-Ser-Lys-Leu-NH2. Grade: >98%. CAS No. 1159767-83-5. Molecular formula: C80H145N19O20. Mole weight: 1693.15. | |
| Alyteserin-2Ma | Alyteserin-2Ma is an antimicrobial peptide produced by Alytes maurus (Midwife toad). It has antibacterial and antifungal activity. It is active against Gram-negative bacterium: Escherichia coli NCTC 10418 (MIC=38.4 μM) and Gram-positive bacterium: Staphylococcus aureus NCTC 10788 (MIC=9.5 μM). It only inhibits C. albicans at very high concentration of 150 uM. Synonyms: Phe-Ile-Gly-Lys-Leu-Ile-Ser-Ala-Ala-Ser-Gly-Leu-Leu-Ser-His-Leu-NH2. Grade: ≥97%. Molecular formula: C76H128N20O19. Mole weight: 1625.98. | |
| Alyteserin-2Mb | Alyteserin-2Mb is an antimicrobial peptide produced by Alytes maurus (Midwife toad). It has antibacterial and antifungal activity. It is active against Gram-positive bacterium: Staphylococcus aureus NCTC 10788 (MIC=19.3 μM). It only inhibits C. albicans at very high concentration of 310 uM. Synonyms: Ile-Leu-Gly-Ala-Ile-Ile-Pro-Leu-Val-Ser-Gly-Leu-Leu-Ser-His-Leu-NH2. Grade: ≥96%. Molecular formula: C77H135N19O18. Mole weight: 1615.04. | |
| Alytesin | Alytesin. Group: Biochemicals. Grades: Purified. CAS No. 31078-12-3. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Alytesin | Alytesin is an amphibian bombesin-like peptide originally isolated from the skin of the European amphibian, alytes obstetricans. It has biological activity very similar to bombesin. It could cause rat uterine contraction, intestinal contraction, gastric acid secretion and hypertension in vivo in the dog. It also adjusts thermoregulation following central administration in vivo. Synonyms: Alytesin; 31078-12-3; CID 16131139; XGRLGTQWAVGHLM; Alytesin (trifluoroacetate salt); BDBM85497; DTXSID40185027; Pgly-arg-leu-gly-thr-gln-trp-ala-val-gly-his-leu-met-NH2; AKOS024456835; AKOS040764257; CAS_31078-12-3; HY-103276; CS-0026803; J-018236. CAS No. 31078-12-3. Molecular formula: C68H106N22O17S. Mole weight: 1535.78. | |
| ALZ-801 | ALZ-801 is a novel and orally available prodrug of tramiprosate that is undergoing a clinical trial for the treatment of Alzheimer's disease (AD). Compared to tramiprosate, ALZ-801 improves some critical properties including tolerability, pharmacokinetic and pharmacodynamic profile, as well as metabolic stability. It inhibits the toxic amyloid oligomers formation associated with AD, which is a discovery of new mechanism of AD prevention. Uses: Prevention of alzheimer's disease (ad). Synonyms: ALZ-801; ALZ 801; ALZ801. | |
| Al/Zn/Mg/Cu Alloy, 50g Chips | Al/Zn/Mg/Cu Alloy, 50g Chips. Uses: For analytical and research use. Group: Aluminium base; metal alloys. Pack Sizes: 50G. Catalog: APS00698. Format: Chips. Shipping: Room Temperature. | |
| AM-001 | AM-001 is a non-competitive inhibitor of Epac1 that blocks the activation of Rap1, a downstream effector of Epac1, in cultured cells. AM-001 can be used in heart disease-related research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 340817-81-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-126133. | |
| AM-0466 | AM-0466 is a potent and selective Nav1.7 inhibitor (IC50 = 0.020 nM). It exhibited an effective activity in a NaV1.7-dependent model of histamine-induced pruritus (itch) and also in a capsaicin-induced nociception model of pain. Synonyms: AM 0466; AM0466. CAS No. 1642113-59-4. Molecular formula: C27H19F3N4O4S. Mole weight: 552.52. | |
| AM-0687 | This active molecular is a selective PI3Kδ inhibitor. PI3Kδ is hyperactivated in B-cell malignancies and plays a vital role in the B-cell receptor pathway. AM-0687 has Cellular potency: pAKT IC50 = 0.7 nM; HWB, u (pAKT) IC 50 = 4.6 nM. AM-0687 shows excellent potency and selectivity profile in biochemical and cellular assays. Uses: Cancer drug candidate. Synonyms: AM-0687; AM 0687; AM0687. 2 - ((1S) - 1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-6-fluoro - N - methyl-3-(2-pyridinyl)-4-quinolinecarboxamide. Grade: 98%. CAS No. 1259522-94-5. Molecular formula: C23H19FN8O. Mole weight: 442.46. | |
| AM 0902 | AM 0902 is an effective and selective TRPA1 antagonist and has been found to exhibit activities in biological pathways associated with pain. Synonyms: AM-0902; AM 0902; AM0902. 1-[[3-[2-(4-Chlorophenyl)ethyl]-1,2,4-oxadiazol-5-yl]methyl]-1,7-dihydro-7-methyl-6H-purin-6-one. Grade: ≥98% by HPLC. CAS No. 1883711-97-4. Molecular formula: C17H15ClN6O2. Mole weight: 370.79. | |
| AM-0902 | AM-0902 is a potent, selective transient receptor potential A1 (TRPA1) antagonist with IC50s of 71 and 131 nM for rTRPA1 and hTRPA1, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1883711-97-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108329. | |
| AM095 | AM095 is a selective LPA 1 receptor antagonist. The IC 50 for AM095 antagonism of LPA-induced calcium flux of human or mouse LPA 1 -transfected CHO cells is 0.025 and 0.023 μM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1345614-59-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-16039. | |
| AM095 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| AM095 | AM095, an effective LPA1 receptor antagonist, has been found to decrease dermal fibrosis caused by attenuates bleomycin. IC50: 0.98 uM and 0.73 uM for human and mouse LPA1 respectively. Synonyms: AM095 (free acid); AM-095; AM 095. Grade: 98%. CAS No. 1228690-36-5. Molecular formula: C27H24N2O5. Mole weight: 456.49. | |
| AM095 free acid | AM095 (free acid) is a potent LPA1 receptor antagonist with IC 50 values of 0.98 and 0.73 μM for recombinant human or mouse LPA1 respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1228690-36-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-16040. | |
| AM095 sodium | AM095 is a selective LPA1 receptor antagonist. The IC50 for AM095 antagonism of LPA-induced calcium flux of human or mouse LPA1-transfected CHO cells is 0.025 and 0.023 μM, respectively. Synonyms: AM-095 sodium; AM 095 sodium. Grade: >98%. CAS No. 1345614-59-6. Molecular formula: C27H23N2NaO5. Mole weight: 478.48. | |
| AM103 | AM 103 is a potent and selective inhibitor of FLAP, with an IC50 of 4.2 nM. Synonyms: 1H-Indole-2-propanoic acid, 3-[(1,1-dimethylethyl)thio]-1-[[4-(6-methoxy-3-pyridinyl)phenyl]methyl]-α,α-dimethyl-5-(2-pyridinylmethoxy)-, sodium salt (1:1); Sodium 3-{1-[4-(6-methoxy-3-pyridinyl)benzyl]-3-[(2-methyl-2-propanyl)sulfanyl]-5-(2-pyridinylmethoxy)-1H-indol-2-yl}-2,2-dimethylpropanoate. Grade: 95%. CAS No. 1147872-22-7. Molecular formula: C36H38N3NaO4S. Mole weight: 631.76. | |
| AM103 | AM 103 is a potent and selective FLAP inhibitor, with an IC 50 value of 4.2 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1147872-22-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14163. | |
| AM-114 | AM 114 is an inhibitor of chymotrypsin-like activity of the 20S proteasome. In addition, AM-114 shows anticancer activity, It can inhibit cell growth in human colon cancer HCT116 p53+/+ cells. Uses: Anticancer. Synonyms: AM-114; AM 114; AM114; Proteasome Inhibitor IX; ((1Z,1'Z)-(1-methyl-4-oxopiperidine-3,5-diylidene)bis(methanylylidene))bis(4,1-phenylene))diboronic acid. Grade: 98%. CAS No. 856849-35-9. Molecular formula: C20H21B2NO5. Mole weight: 377.01. | |
| AM 1172 | AM 1172, an AEA analogue, has been found to be an anandamide uptake inhibitor as well as a cannabinoid receptor partial agonist. Synonyms: AM 1172; AM1172; AM-1172; N-(5Z,8Z,11Z,14Z)-5,8,11,14-eicosatetraen-1-yl-4-hydroxybenzamide. Grade: ≥98% by HPLC. CAS No. 251908-92-6. Molecular formula: C27H39NO2. Mole weight: 409.60. | |
| AM 1172 | AM 1172. Group: Biochemicals. Grades: Purified. CAS No. 251908-92-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| AM12 | AM12 inhibits Lanthanide-evoked TRPC5 activity with an IC50 of 0.28 μM. Synonyms: 2-(2-Bromophenyl)-3,5,7-trihydroxy-4H-chromen-4-one; 3,5,7-Trihydroxy-2-(2-bromophenyl)-4H-chromen-4-one; 4H-1-Benzopyran-4-one, 2-(2-bromophenyl)-3,5,7-trihydroxy-; AM 12; AM-12. Grade: ≥90%. CAS No. 2387510-84-9. Molecular formula: C15H9BrO5. Mole weight: 349.13. | |
| AM 12 | AM 12 is a TRPC5 inhibitor with an IC50 value of 0.28 μM, which exhibits some selectivity for TRPC5 over TRPC2, 3 and 4. Synonyms: 2-(2-Bromophenyl)-3,5,7-trihydroxy-4H-chromen-4-one. Grade: ≥97%. Molecular formula: C15H9BrO5. Mole weight: 349.14. | |
| AM1241 | AM-1241 is a selective cannabinoid CB2 receptor agonist with Ki of 3.4 nM, exhibits 82-fold selectivity over CB1 receptor. Synonyms: AM 1241; AM-1241; (1-(Methylpiperidin-2-ylmethyl)-3-(2-iodo-5-nitrobenzoyl)indole); (R,S)-3-(2-Iodo-5-nitrobenzoyl)-1-(1-methyl-2-piperidinylmethyl)-1H-indole. Grade: >98%. CAS No. 444912-48-5. Molecular formula: C22H22IN3O3. Mole weight: 503.33. | |
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