American Chemical Suppliers
A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
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Product | Description | |
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Ametoctradin 100 μg/mL in Acetonitrile Quick inquiry Where to buy Suppliers range | Ametoctradin 100 μg/mL in Acetonitrile. Uses: For analytical and research use. Group: Pesticides & Metabolites; Pesticides & Metabolites. CAS No. 865318-97-4. Pack Sizes: 1ML. IUPAC Name: 5-ethyl-6-octyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine. Molecular formula: C15H25N5. Mole weight: 275.39. Catalog: APS865318974A. SMILES: CCCCCCCCc1c(N)n2ncnc2nc1CC. Format: Single Solution. Shipping: Room Temperature. | |
Ametoctradin metabolite M650F01 hydrochloride Quick inquiry Where to buy Suppliers range | Ametoctradin metabolite M650F01 hydrochloride. Uses: For analytical and research use. Group: Pesticides & Metabolites; Pesticides & Metabolites. IUPAC Name: 4-(7-amino-5-ethyl-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)butanoic acid;hydrochloride. Molecular formula: C11H15N5O2.ClH. Mole weight: 285.73. Catalog: APS005733. SMILES: Cl.CCc1nc2ncnn2c(N)c1CCCC(=O)O. Format: Neat. Product Type: Metabolite. Shipping: Room Temperature. | |
Ametoctradin metabolite M650F06 hydrochloride Quick inquiry Where to buy Suppliers range | Ametoctradin metabolite M650F06 hydrochloride. Uses: For analytical and research use. Group: Pesticides & Metabolites; Pesticides & Metabolites. Alternative Names: 6-(7-amino-5-ethyl[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)hexanoic acid. IUPAC Name: 6-(7-amino-5-ethyl-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)hexanoic acid;hydrochloride. Molecular formula: C13H19N5O2.ClH. Mole weight: 313.78. Catalog: APS005734. SMILES: Cl.CCc1nc2ncnn2c(N)c1CCCCCC(=O)O. Format: Neat. Product Type: Metabolite. Shipping: Room Temperature. | |
Ametryn Quick inquiry Where to buy Suppliers range | Ametryn. Group: Biochemicals. Alternative Names: Ametryne; Cemerin; Doruplant; Evik; G 34162; Gesapax; N-Ethyl-N'-(1-methylethyl)-6-(methylthio)-1,3,5-triazine-2,4-diamine; NSC 163044; Primatol Z 80; 2-Ethylamino-4-isopropylamino-6-methylmercapto-s-triazine; 2-Ethylamino-4-isopropylamino-6-methylthio-1,3,5-triazine; 2-Ethylamino-4-isopropylamino-6-methylthio-s-triazine; 2-Ethylamino-4-methylthio-6-isopropylamino-1,3,5-triazine; 2-Methylmercapto-4-ethylamino-6-isopropylamino-s-triazine; 2-Methylthio-4-ethylamino-6-isopropylamino-s-triazine; 2-Methylthio-4-ethylamino-6-isopropylamino-sym-triazine; A 1093; Amephyt; Ametrex; 2-(Ethylamino)-4-(isopropylamino)-6-(methylthio)-s-triazine; N-Ethyl-N'-(1-methylethyl)-6-(methylthio)-1,3,5-triazine-2,4-diamine; N2-Ethyl-N4-(1-methylethyl)-6-(methylthio)-1,3,5-triazine-2,4-diamine. Grades: Highly Purified. CAS No. 834-12-8. Pack Sizes: 1g. Molecular Formula: C9H17N5S, Molecular Weight: 227.33. US Biological Life Sciences. | Worldwide |
Ametryn-N-nitroso Quick inquiry Where to buy Suppliers range | Ametryn-N-nitroso. Uses: For analytical and research use. Group: Pesticides & Metabolites; Pesticides & Metabolites. IUPAC Name: N-ethyl-N-[4-methylsulfanyl-6-(propan-2-ylamino)-1,3,5-triazin-2-yl]nitrous amide. Molecular formula: C9H16N6OS. Mole weight: 256.33. Catalog: APS005735. SMILES: CCN(N=O)c1nc(NC(C)C)nc(SC)n1. Format: Neat. Product Type: Metabolite. Shipping: Room Temperature. | |
Amezinium methylsulfate Quick inquiry Where to buy Suppliers range | Amezinium methylsulfate, a sympathomimetic drug used for the treatment of low blood pressure, increases the arterial blood pressure and heart rate of anaesthetized animals and of pithed rats by stimulating vascular alpha- and cardiac beta 1-adrenoceptors. Synonyms: Amezinium Metilsulfate; LU-1631; LU 1631; LU1631; Regulton; Risumic. 6-methoxy-1-phenylpyridazin-1-ium-4-amine methylsulfate;AMEZINIUM METHYL SULFATE;SUPRATONIN (GRUNENTHAL);RISUMIC (DAINIPPON);REGULTON (KNOLL);4-amino-6-methoxy-1-phenyl-pyridaziniumethylsulfate;4-amino-6-methoxy-1-phenylpyridazinium-methylsulfat;4-amino-. CAS No. 30578-37-1. Molecular formula: C11H12N3O.CH3O4S. Mole weight: 313.33. | |
Amezinium Methyl Sulfate Quick inquiry Where to buy Suppliers range | Amezinium Methyl Sulfate. Group: Biochemicals. Grades: Highly Purified. CAS No. 30578-37-1. Pack Sizes: 250mg, 5mg, 10g, 25g, 50g. Molecular Formula: C12H15N3O5S. US Biological Life Sciences. | Worldwide |
Amfenac Quick inquiry Where to buy Suppliers range | Amfenac, 51579-82-9, 2-(2-amino-3-benzoylphenyl)acetic acid, Amfenaco, Amfenacum, (2-Amino-3-benzoylphenyl)acetic acid, (2-Amino-3-benzoylphenyl)essigsaeure, CHEBI:75915, Amfenac [INN:BAN], Amfenacum [INN-Latin], Amfenaco [INN-Spanish], NSC-309467, UNII-28O5C1J38A, 28O5C1J38A, 2-amino-3-benzoylbenzeneacetic acid, 2-Amino-3-Benzoylphenylacetic Acid, Amfenac (INN), NSC 309467, AMFENAC [INN], AHR-5850D, Fenazox (Japan), AMFENAC [MI], AMFENAC [WHO-DD], SCHEMBL24249, CHEMBL25146, GTPL7565, DTXSID90199533, BDBM50225110, MFCD00866133, NSC309467, 2-(2-amino-3-benzoylphenyl)aceticacid, SY265113, 2-[2-amino-3-(benzoyl)phenyl]acetic acid, FT-0764816, D07443, SR-01000944946, Q4745976, SR-01000944946-1. | |
Amfenac Quick inquiry Where to buy Suppliers range | Amfenac (2-Amino-3-benzoylbenzeneacetic acid) is a non-steroidal anti-inflammatory drug with acetic acid moiety. Synonyms: 2-Amino-3-benzoylphenylacetic acid; 2-Amino-3-benzoylbenzeneacetic acid; 2-(2-amino-3-benzoyl-phenyl)acetic acid. Grades: > 95%. CAS No. 51579-82-9. Molecular formula: C15H13NO3. Mole weight: 255.28. | |
Amfenac Lactam Quick inquiry Where to buy Suppliers range | A metabolite of Amfenac. Synonyms: 7-Benzoyl-1,3-dihydro-2H-indol-2-one; 7-Benzoyl-2-indolinone. Grades: > 95%. CAS No. 51135-38-7. Molecular formula: C15H11NO2. Mole weight: 237.26. | |
Amfenac Sodium Hydrate Quick inquiry Where to buy Suppliers range | Amfenac is an antibacterial agent. Group: Biochemicals. Alternative Names: 2-Amino-3-benzoylbenzeneacetic Acid Sodium Salt Hydrate; (2-Amino-3-benzoylphenyl)acetic Acid; NSC 309467. Grades: Highly Purified. CAS No. 61618-27-7. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
Amfenac sodium salt hydrate Quick inquiry Where to buy Suppliers range | Amfenac sodium salt hydrate. Group: Biochemicals. Alternative Names: 2-Amino-3-benzoylbenzeneacetic acid sodium salt hydrate; (2-Amino-3-benzoylphenyl)acetic acid; NSC 309467. Grades: Highly Purified. CAS No. 61618-27-7. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C15H14NNaO4. US Biological Life Sciences. | Worldwide |
Amfetamine Hydrochloride Quick inquiry Where to buy Suppliers range | Amfetamine Hydrochloride. Uses: For analytical and research use. Group: API Standards; Pharmaceutical Toxicology. Alternative Names: (+/-)-alpha-Methylphenethylamine hydrochloride, beta-Phenylisopropylamine hydrochloride, Psychedrine, Psychedrine hydrochloride, alpha-Methylbenzeneethanamine hydrochloride, alpha-Methylphenethylamine hydrochloride, Amphetamine hydrochloride, dl-Amphetamine hydrochloride, Benzeneethanamine, alpha-methyl-, hydrochloride, (+/-)-, (+/-)-Amphetamine hydrochloride, Benzeneethanamine, alpha-methyl-, hydrochloride (1:1), 1-Phenyl-2-propylamine hydrochloride, Phenethylamine, alpha-methyl-, hydrochloride, (+/-)-,Amfetamine Hydrochloride, Benzeneethanamine, alpha-methyl-, hydrochloride. CAS No. 2706-50-5. IUPAC Name: 1-phenylpropan-2-amine;hydrochloride. Molecular formula: C9H13N.ClH. Mole weight: 171.67. Catalog: APS2706505. SMILES: Cl.CC(N)Cc1ccccc1. Format: Neat. Product Type: API/ Impurity. Shipping: Room Temperature. | |
Amfetamine sulfate Quick inquiry Where to buy Suppliers range | Amfetamine sulfate. Uses: For analytical and research use. Group: API Standards; European Pharmacopoeia (Ph. Eur.); Impurity Standards; Pharmaceutical Toxicology; Pharmacopoeial Standards. Alternative Names: Selegiline Hydrochloride Imp. B (EP), Amphetamine sulfate, Psychoton, alpha-Methyl-benzeneethanamine sulfate (2:1), Phenamine, alpha-Methylbenzeneethanamine sulfate (2:1), dl-Amphetamine sulphate, dl-Amphetamine sulfate, Benzedrine sulfate, Selegiline Imp. B (EP), (+/-)-alpha-Methyl-phenethylamine sulfate (2:1), (+/-)-Amphetamine sulfate,DL-Amphetamine sulphate, Penamine, NSC 170999, dl-Phenamine sulfate, Alentol, Amphetamine sulphate, DL-Amphetamine hydrogen sulfate, (+/-)-Phenisopropylamine sulfate, 1-Phenyl-2-aminopropane sulfate, Fenamin, Simpamina, Centramine, Phenamine (sympathomimetic), Phenamine sulfate, dl-alpha-Methylphenethylamine sulfate, (+/-)-alpha-Methyl-benzeneethanamine sulfate (2:1), (+/-)-2-Amino-1-phenylpropane sulfate, Phenamin. CAS No. 60-13-9. Pack Sizes: 250MG. IUPAC Name: 1-phenylpropan-2-amine;sulfuric acid. Molecular formula: 2C9H13N.H2O4S. Mole weight: 368.49. Catalog: APS60139A. SMILES: CC(N)Cc1ccccc1. CC(N)Cc2ccccc2. OS(=O)(=O)O. Format: Neat. Product Type: API. Shipping: Room Temperature. | |
Amfetaminil Quick inquiry Where to buy Suppliers range | Amfetaminil. Group: Heterocyclic Organic Compound. Alternative Names: AMFETAMINIL; amphetaminil; AN-1; Aponeuron; α -[ (1-Methyl-2-phenylethyl) amino]benzeneacetonitrile; α -[ (α -Methylphenethyl) amino]benzeneacetonitrile; 2-[ (1-methyl-2-phenyl-ethyl) amino]-2-phenyl-acetonitrile; 2-phenyl-2- (1-phenylpropan-2-ylamino) acetonitrile. CAS No. 17590-01-1. Molecular formula: C17H18N2. Mole weight: 250.34. Melting Point: 81-85?C. | |
Amflutizole Quick inquiry Where to buy Suppliers range | Amflutizole is a xanthine oxidase inhibitor. It inhibits free radical generation in the ischemic/reperfused rat cerebral cortex. Synonyms: 4-Amino-3-(3-(trifluoromethyl)phenyl)isothiazole-5-carboxylic acid. CAS No. 82114-19-0. Molecular formula: C11H7F3N2O2S. Mole weight: 288.25. | |
Amfonelic acid Quick inquiry Where to buy Suppliers range | Amfonelic acid. Group: Heterocyclic Organic Compound. Alternative Names: AMFONELIC ACID;AMFONELIC ACID INCREASES DOPAMINE RE;amfonelic acid (7-benzyl-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid);Amfonelic;7-Benzyl-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylicacid;NCA;NSC-100638;WIN-25978. CAS No. 15180-02-6. Product ID: ACM15180026. Molecular formula: C18H16N2O3. Mole weight: 308.33. Appearance: powder. Boiling Point: 499°C. Melting Point: >1000 °C. Flash Point: 256°C. Density: 1.297. | |
Amfonelic acid Quick inquiry Where to buy Suppliers range | Amfonelic acid (AFA; WIN 25,978) is a research chemical and dopaminergic stimulant with antibiotic properties. Synonyms: AMFONELIC ACID; AMFONELIC ACID INCREASES DOPAMINE RE; amfonelic acid (7-benzyl-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid); Amfonelic; 7-Benzyl-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid; NCA. Grades: 95%. CAS No. 15180-02-6. Molecular formula: C18H16N2O3. Mole weight: 308.33. | |
AMG-009 Quick inquiry Where to buy Suppliers range | AMG-009 is an orally active, small molecule dual D prostanoid(DP) receptor and chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2) antagonist. It was in preclinical development for the treatment of asthma and allergic rhinitis. It was developed by Amgen Inc. Uses: Amg-009 was in preclinical development for the treatment of asthma and allergic rhinitis. Synonyms: AMG-009; AMG 009; AMG009; 2-[4-[4- (Butylcarbamoyl) -2-[ (2, 4-dichlorophenyl) sulfonylamino]phenoxy]-3-methoxyphenyl]acetic acid;AMG009;Benzeneacetic acid, 4- (4- ( (butylamino) carbonyl) -2- ( ( (2, 4-dichlorophenyl) sulfonyl) amino) phenoxy) -3-methoxy-. Grades: >98 %. CAS No. 1027847-67-1. Molecular formula: C26H26Cl2N2O7S. Mole weight: 581.46. | |
AMG-126737 Quick inquiry Where to buy Suppliers range | AMG-126737 is a potent inhibitor of human lung mast cell tryptase (Ki = 90 nM), with greater than 10- to 200-fold selectivity versus other serine proteases. Synonyms: 3- [ [4- [5- [4- [ [ (3-carbamimidoylphenyl) sulfonylamino] methyl] phenoxy] pentoxy] phenyl] methylsulfamoyl] benzenecarboximidamide; 1,5-bis-(4-((3-carbamimidoyl-benzenesulfonylamino)-methyl)-phenoxy)-pentane; AMG-126737; AMG 126737; AMG126737. Grades: >98%. CAS No. 224054-76-6. Molecular formula: C33H38N6O6S2. Mole weight: 678.82. | |
AMG 18 hydrochloride Quick inquiry Where to buy Suppliers range | AMG-18 hydrochloride is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM. AMG-18 is a potent and selective IRE1α inhibitor with IC50 of 13 nM for recombinant and IC50 of 99 nM for cellular IRE1&alpha. Synonyms: 2-Chloro-N-[6-methyl-5-[[3-[2-[(3S)-3-piperidinylamino]-4-pyrimidinyl]-2-pyridinyl]oxy]-1-naphthalenyl]benzenesulfonamide hydrochloride; Kira8 hydrochloride. Grades: ≥98% by HPLC. Molecular formula: C31H29ClN6O3S·HCl. Mole weight: 637.58. | |
AMG208 Quick inquiry Where to buy Suppliers range | AMG 208 is a selective small-molecule inhibitor of the proto-oncogene c-Met with potential antineoplastic activity. C-Met encodes the hepatocyte growth factor receptor tyrosine kinase, plays an important role in epithelial cell proliferation and has been shown to be overexpressed in a variety of cancers. Synonyms: AMG-208; AMG208; AMG 208. Grades: 0.98. CAS No. 1002304-34-8. Molecular formula: C22H17N5O2. Mole weight: 383.411. | |
AMG 21629 Quick inquiry Where to buy Suppliers range | AMG 21629 has been found to be an effective and selective TRPV1 antagonist, which could probably be useful in the treatment of pains associated with cancer and inflammatory diseases. Synonyms: AMG21629; AMG-21629; AMG 21629; 3-Amino-5-[[2-[(2-methoxyethyl)amino]-6-[4-(trifluoromethyl)phenyl]-4-pyrimidinyl]oxy]-2(1H)-quinoxalinone. Grades: ≥97% by HPLC. CAS No. 939040-79-6. Molecular formula: C22H19F3N6O3. Mole weight: 472.42. | |
AMG232 Quick inquiry Where to buy Suppliers range | AMG232 is an extremely potent MDM2 inhibitor with remarkable pharmacokinetic properties and in vivo antitumor activity in the SJSA-1 osteosarcoma xenograft model (ED50 = 9.1 mg/kg). AMG232 is currently under clinical development. Synonyms: AMG-232; AMG 232. Grades: 0.98. CAS No. 1352066-68-2. Molecular formula: C28H35Cl2NO5S. Mole weight: 568.55. | |
AMG319 Quick inquiry Where to buy Suppliers range | AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, >47-fold selectivity over other PI3Ks. Phase 2. Synonyms: AMG319; AMG-319; AMG 319; ACP319; ACP-319; ACP 319. Grades: 98%. CAS No. 1608125-21-8. Molecular formula: C21H16FN7. Mole weight: 385.4. | |
AMG 333 Quick inquiry Where to buy Suppliers range | AMG 333 is a potent and highly selective TRPM8 antagonist with an IC50 of 13 nM for hTRPM8 and IC50 of 20 nM for rTRPM8, which displays high selectivity over other TRP channels (IC50>20 uM, TRPV1/V3/V4/A1). AMG-333 was well-tolerated in 28 day rat and dog preclinical safety studies and advanced to Phase 1 human clinical trials. Synonyms: 6-[[[ (S) - (3-Fluoro-2-pyridinyl) [3-fluoro-4- (trifluoromethoxy) phenyl]methyl]amino]carbonyl]-3-pyridinecarboxylic acid. Grades: ≥98% by HPLC. CAS No. 1416799-28-4. Molecular formula: C20H12F5N3O4. Mole weight: 453.33. | |
AMG-337 Quick inquiry Where to buy Suppliers range | AMG 337 is an orally bioavailable inhibitor of the proto-oncogene c-Met with potential antineoplastic activity. c-Met inhibitor AMG 337 selectively binds to c-Met, thereby disrupting c-Met signal transduction pathways. Synonyms: AMG337; AMG-337; AMG 337. Grades: 98%. CAS No. 1173699-31-4. Molecular formula: C23H22FN7O3. Mole weight: 463.47. | |
AMG 369 Quick inquiry Where to buy Suppliers range | This active molecular is a S1P1/S1P5 agonist with limited activity at S1P3. AMG 369 has no activity at S1P2 and S1P4. AMG-369 is shown to reduce blood lymphocyte counts 24 hours postdose with dosed orally at 0.1 mg/kg. Till Jun 2016, no recent reports of development identified for preclinical development in Multiple-sclerosis in USA were published yet. Uses: Multiple sclerosis. Synonyms: AMG-369; AMG 369; AMG369; KB-74649; KB74649; KB 74649. 1-[[3-fluoro-4-[6-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]phenyl]methyl]azetidine-3-carboxylicacid; ZINC216149127;1202073-26-4. Grades: 98%. CAS No. 1202073-26-4. Molecular formula: C26H22FN3O2S. Mole weight: 459.54. | |
AMG-3969 Quick inquiry Where to buy Suppliers range | AMG-3969 is a potent and selective disruptor of glucokinase-glucokinase regulatory protein interaction (GK-GKRP). AMG-3969 can modulate the blood glucose levels in rodent models of diabetes. Synonyms: 2-[4-[(2S)-4-(6-aminopyridin-3-yl)sulfonyl-2-prop-1-ynylpiperazin-1-yl]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol. Grades: 98% by HPLC. CAS No. 1361224-53-4. Molecular formula: C21H20F6N4O3S. Mole weight: 522.466. | |
AMG-458 Quick inquiry Where to buy Suppliers range | AMG 458 is a potent c-Met inhibitor with Ki of 1 nM ~ 2.0 nM. AMG-458 was found to significantly inhibit tumor growth in the NIH3T3/TPR-Met and U-87 MG xenograft models with no adverse effect on body weight. Synonyms: AMG458; AMG 458; 1-(2-Hydroxy-2-methylpropyl)-N-[5-[(7-methoxyquinolin-4-yl)oxy]pyridin-2-yl]-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide; 2,3-Dihydro-1-(2-hydroxy-2-methylpropyl)-N-[5-[(7-methoxy-4-quinolinyl)oxy]-2-pyridinyl]-5-methyl-3-oxo-2-phenyl-1H-pyrazole-4-carboxamide. Grades: ≥98%. CAS No. 913376-83-7. Molecular formula: C30H29N5O5. Mole weight: 539.58. | |
AMG-47a Quick inquiry Where to buy Suppliers range | AMG-47a is a potent inhibitor of Lck and T cell proliferation. It has anti-inflammatory activity (ED50 = 11 mg/kg) in the anti-CD3 induced production of IL-2 in mice. It displays subnanomolar inhibition against Lck, and low inhibition against other hard to inhibit kinases in several other in vitro assays. It effectively inhibits the JNK family of kinases including TYK2 at ~ 1.2 μM but well under 10 μM. It selectively reduced the levels of EGFP-KRASG12V protein but did not affect EGFP protein in cells. Uses: Amg-47a has anti-inflammatory activity. Synonyms: AMG-47a; AMG 47a; AMG47a; AMG-47; AMG 47; AMG47. 4-Methyl-3-[2-[[2-(4-morpholinyl)ethyl]amino]-6-quinazolinyl]-N-[3-(trifluoromethyl)phenyl]benzamide. Grades: 95%. CAS No. 882663-88-9. Molecular formula: C29H28F3N5O2. Mole weight: 535.56. | |
AMG 487 Quick inquiry Where to buy Suppliers range | AMG 487 is a CXCR3 antagonist that inhibits cell migration and metastasis. Synonyms: AMG-487; AMG 487; AMG487. Benzeneacetamide, N-((1R)-1-(3-(4-ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl)ethyl)-N-(3-pyridinylmethyl)-4-(trifluoromethoxy)-; N-[(1R)-1-[3-(4-ethoxyphenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(pyridin-3-ylmethyl)-2-[4-(trifluorome. CAS No. 473719-41-4. Molecular formula: C32H28F3N5O4. Mole weight: 603.59. | |
AMG-510 Quick inquiry Where to buy Suppliers range | AMG-510 Inhibitor. Uses: Scientific use. Product Category: T8684. CAS No. 2296729-00-3. | |
AMG510 Quick inquiry Where to buy Suppliers range | AMG-510 is a potent KRAS G12C covalent inhibitor with potential antineoplastic activity. At the 2019 World Conference on Lung Cancer (WCLC), Amgen declared the efficacy of AMG 510 for treating non-small cell lung cancer (NSCLC) with KRAS G12 C-mutated solid tumors. Amgen also announced prospective directions for AMG510 through academic scholars and reports the few limitations on official drug release as evidence for potential investors to consider the value of AMG 510. Synonyms: AMG 510; AMG-510; Sotorasib. Grades: ≥98%. CAS No. 2252403-56-6. Molecular formula: C30H30F2N6O3. Mole weight: 560.59. | |
AMG510 racemate Quick inquiry Where to buy Suppliers range | AMG510 is a potent KRAS G12C covalent inhibitor with potential antineoplastic activity. At the 2019 World Conference on Lung Cancer (WCLC), Amgen declared the efficacy of AMG510 for treating non-small cell lung cancer (NSCLC) with KRAS G12 C-mutated solid tumors. Amgen also announced prospective directions for AMG510 through academic scholars and reports the few limitations on official drug release as evidence for potential investors to consider the value of AMG510. Uses: Immune checkpoint inhibitors. Synonyms: AMG-510 racemate; AMG 510 racemate; Sotorasib racemate. CAS No. 2296729-00-3. Molecular formula: C30H30F2N6O3. Mole weight: 560.59. | |
AMG-517 Quick inquiry Where to buy Suppliers range | AMG-517 is a potent and selective TRPV1 antagonist, antagonizes capsaicin, proton, and heat activation of TRPV1 with IC50 of 0.76 nM, 0.62 nM and 1.3 nM. Synonyms: AMG-517; AMG 517; AMG517; BD-0082; BD 0082; BD0082; BAY E 9736. Grades: >98%. CAS No. 659730-32-2. Molecular formula: C20H13F3N4O2S. Mole weight: 430.4. | |
AMG 548 Quick inquiry Where to buy Suppliers range | AMG 548. Group: Biochemicals. Grades: Purified. CAS No. 864249-60-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
AMG 548 Quick inquiry Where to buy Suppliers range | AMG-548 is a selective p38α inhibitor with Ki value of 0.5nM. It displays >1000-fold selectivity against 36 other kinases, and it can inhibit whole blood LPS-stimulated TNF&alpha. In Sep 2008, Preclinical for Rheumatoid arthritis in USA was discontinued. Uses: Inflammation; rheumatoid arthritis. Synonyms: AMG 548; AMG-548; AMG548; UNII-PGR0H531I4; 2-[[(2S)-2-Amino-3-phenylpropyl]amino]-3-methyl-5-(2-naphthalenyl)-6-(4-pyridinyl)-4(3H)-pyrimidinone. Grades: 98%. CAS No. 864249-60-5. Molecular formula: C29H27N5O. Mole weight: 461.56. | |
AMG 548 (2-[[(2S)-2-Amino-3-phenylpropyl]amino]-3-methyl-5-(2-naphthalenyl)-6-(4-pyridinyl)-4(3H)-pyrimidinone) Quick inquiry Where to buy Suppliers range | Potent and selective inhibitor of p38alpha (Ki values are 0.5, 3.6, 2600 and 4100nm for p38a, p38beta, p38gamma and p38delta respectively). Displays >1000-fold selectivity against 36 other kinases; inhibits whole blood LPS-stimulated TNFalpha (IC50 = 3nm). Group: Biochemicals. Grades: Highly Purified. CAS No. 864249-60-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
AMG-548 dihydrochloride Quick inquiry Where to buy Suppliers range | ≥98% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 864249-60-5 (free base). Pack Sizes: 25MG. Mole weight: 534.48. Catalog: ALP864249605. Assay: ≥98% (HPLC). | |
AMG-628 Quick inquiry Where to buy Suppliers range | AMG-628 is a highly selective, ATP-competitive inhibitor of Raf kinases. It can inhibit activation of tyrosine protein kinases. AMG-628 can also inhibit growth, and induce cell cycle arrest and apoptosis in colon and melanoma cell lines with the B-RafV600E mutation. Synonyms: AMG-628; AMG 628; AMG628; UNII-28J966TN3X; CHEMBL226574;N-(4-((6-(4-(1-(4-fluorophenyl)ethyl)-1-piperazinyl)-4-pyrimidinyl)oxy)-2-benzothiazolyl)-Acetamide. Grades: 98%. CAS No. 862269-73-6. Molecular formula: C25H25FN6O2S. Mole weight: 492.57. | |
AMG-747 Quick inquiry Where to buy Suppliers range | AMG-747 is a GlyT-1 inhibitor. It has been under investigation to treat various CNS disorders that may be ameliorated by modulation of either inhibitory glycinergic or excitatory glutamatergic neurotransmission. It was used as an antipsychotic drug. It was developed by Amgen and was terminated in Cilnic phase 2. Uses: Amg-747 was used as an antipsychotic drug. Synonyms: 1-Piperazineacetic acid, 4- ( (R) -phenyl (3- (trifluoromethyl) phenyl) methyl) -; 2-[4-[ (R) -phenyl-[3- (trifluoromethyl) phenyl]methyl]piperazin-1-yl]acetic acid; Tilapertin; AMG747; AMG-747; AMG 747. Grades: >98 %. CAS No. 1000690-85-6. Molecular formula: C20H21F3N2O2. Mole weight: 378.39. | |
AMG 837 Quick inquiry Where to buy Suppliers range | AMG 837 sodium salt is a potent GPR40 agonist with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents. It displayed the expected two-fold increase in potency on GPR4 compared to the racemic compound and its activity crossed over to the rat and mouse forms of GPR40. It is a highly potent stimulator of insulin secretion in MIN6 cells with an EC50 comparable to that seen in the aequorin Ca2+-flux assay. It was a potent partial agonist in the calcium flux assay on the GPR40 receptor and potentiated glucose stimulated insulin secretion in vitro and in vivo. Synonyms: AMG-837, AMG837, AMG 837. Grades: >98%. CAS No. 865231-46-5. Molecular formula: C26H21F3O3. Mole weight: 438.44. | |
AMG 837 calcium hydrate Quick inquiry Where to buy Suppliers range | AMG 837 calcium hydrate is a potent GPR40 agonist(EC50=13 nM) with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents. Synonyms: AMG-837; AMG837; AMG 837. Grades: 0.98. CAS No. 1259389-38-2. Molecular formula: C52H42CaF6O7. Mole weight: 455.45. | |
AMG 837 hemicalcium salt Quick inquiry Where to buy Suppliers range | The calcuim salt form of AMG 837, which has been found to be a GPR40 partial agonist and could probably be used as an antidiabetic agent. Synonyms: AMG 837 hemicalcium salt; AMG837 hemicalcium salt; AMG-837 hemicalcium salt; (βS)-β-1-Propyn-1-yl-4-[[4'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]methoxy]benzenepropanoic acid hemicalcium salt. Grades: ≥98% by HPLC. CAS No. 1291087-14-3. Molecular formula: C26H20F3O3.½Ca. Mole weight: 457.47. | |
AMG 837 sodium salt Quick inquiry Where to buy Suppliers range | AMG 837 sodium salt is a potent GPR40 agonist with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents. It displayed the expected two-fold increase in potency on GPR4 compared to the racemic compound and its activity crossed over to the rat and mouse forms of GPR40. It is a highly potent stimulator of insulin secretion in MIN6 cells with an EC50 comparable to that seen in the aequorin Ca2+-flux assay. It was a potent partial agonist in the calcium flux assay on the GPR40 receptor and potentiated glucose stimulated insulin secretion in vitro and in vivo. Synonyms: AMG-837 sodium; AMG837 sodium; AMG 837 sodium; AMG-837 sodium salt. Grades: >98%. CAS No. 865231-45-4. Molecular formula: C26H20F3NaO3. Mole weight: 460.42. | |
AMG8562 Quick inquiry Where to buy Suppliers range | AMG8562 is a novel vanilloid receptor TRPV1 modulator. Synonyms: AMG-8562; AMG8562; AMG 8562; (E)-N-[(2R)-2-hydroxy-2,3-dihydro-1H-inden-4-yl]-3-[2-piperidin-1-yl-4-(trifluoromethyl)phenyl]prop-2-enamide;AMG-8562;2-Propenamide, N-((2R)-2,3-dihydro-2-hydroxy-1H-inden-4-yl)-3-(2-(1-piperidinyl)-4-(trifluoromethyl)phenyl)-, (2E)-. Grades: >98 %. CAS No. 1041478-78-7. Molecular formula: C24H25F3N2O2. Mole weight: 430.47. | |
AMG-8718 Quick inquiry Where to buy Suppliers range | This active molecular is a potent BACE1 inhibitor that is a potential target for the treatment of Alzheimer's disease. AMG-8718 produced significantly reductions of CSF and brain Aβ levels in animal models. It also exhibited reduced potential for QTc elongation in a cardiovascular safety model. BACE1 inhibition has direct efficacy in the Alzheimer's disease pathology but it does not affect viability largely. Uses: The treatment of alzheimer's disease. Synonyms: AMG8718; AMG 8718; AMG-8718. (4S)-7'-(2-fluoropyridin-3-yl)-3'-[2-(3-methyloxetan-3-yl)ethynyl]spiro[5H-1,3-oxazole-4,5'-chromeno[2,3-b]pyridine]-2-amine. Grades: 98%. CAS No. 1215868-94-2. Molecular formula: C25H19FN4O3. Mole weight: 442.45. | |
AMG-900 Quick inquiry Where to buy Suppliers range | AMG 900 is a small-molecule inhibitor of Aurora kinases A, B and C with potential antineoplastic activity. Aurora kinase inhibitor AMG 900 selectively binds to and inhibits the activities of Aurora kinases A, B and C, which may result in inhibition of cellular division and proliferation in tumor cells that overexpress these kinases. Synonyms: AMG900; AMG-900; AMG 900. Grades: 0.98. CAS No. 945595-80-2. Molecular formula: C28H21N7OS. Mole weight: 503.57764. | |
AMG 925 Quick inquiry Where to buy Suppliers range | AMG-925 is a potent, selective, and bioavailable FLT3/cyclin-dependent kinase 4 (CDK4) dual kinase inhibitor. AMG 925 inhibited AML xenograft tumor growth by 96% to 99% without significant body weight loss. The antitumor activity of AMG 925 correlated with the inhibition of STAT5 and RB phosphorylation, the pharmacodynamic markers for inhibition of FLT3 and CDK4, respectively. In addition, AMG 925 was also found to inhibit FLT3 mutants (e.g., D835Y) that are resistant to the current FLT3 inhibitors (e.g., AC220 and sorafenib). AMG 925, which combines inhibition of two kinases essential for proliferation and survival of FLT3-mutated AML cells, may improve and prolong clinical responses. Synonyms: AMG925; AMG-925; AMG 925; FLX925; FLX-925; FLX 925. Grades: >98%. CAS No. 1401033-86-0. Molecular formula: C26H29N7O2. Mole weight: 471.55. | |
AMG-978 Quick inquiry Where to buy Suppliers range | AMG-978 is an inhibitor of beta-secretase 1 (BACE1) (IC50 = 27 nM) which is in the preclinical study for the treatment of Alzheimer's disease. Uses: The potential treatment of alzheimer's disease. Synonyms: AMG 978; AMG978. | |
AMG 9810 Quick inquiry Where to buy Suppliers range | AMG 9810. Group: Biochemicals. Grades: Purified. CAS No. 545395-94-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
AMG 9810 Quick inquiry Where to buy Suppliers range | ≥98% (HPLC), powder. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 545395-94-6. Pack Sizes: 10MG, 50MG. Mole weight: 337.41. Catalog: AP545395946. Assay: ≥98% (HPLC). | |
AMG-9810 Quick inquiry Where to buy Suppliers range | AMG-9810 is potent, non-vanilloid and selective TRPV1 receptor antagonist with IC50 value of 17 nM. It inhibits capsaicin-, proton-, heat- and endogenous ligand-induced activation of human and rat recombinant TRPV1 receptors. It displays antihyperalgesic properties in a rat model of inflammatory pain. It was developed by Amgen. Uses: Amg-9810 displays antihyperalgesic properties. Synonyms: AMG-9810; AMG9810; AMG 9810. (2E)-N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-dimethylethyl)phenyl]-2-propanamide;2-PropenaMide, N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-diMethylethyl)phenyl]-, (2E)-;(E)-3-(4-tert-butylphenyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)prop-2-enami. Grades: 98%. CAS No. 545395-94-6. Molecular formula: C21H23NO3. Mole weight: 337.41. | |
AMG PERK 44 Quick inquiry Where to buy Suppliers range | AMG PERK 44 is a potent and selective PERK inhibitor with IC50 of 6 nM, which exhibits 160-fold selectivity over B-Raf, GCN2 and a panel of 387 other kinases. Synonyms: 4-[2-Amino-4-methyl-3-(2-methyl-6-quinolinyl)benzoyl]-1,2-dihydro-1-methyl-2,5-diphenyl-3H-pyrazol-3-one hydrochloride. Grades: ≥98%. CAS No. 1883548-84-2. Molecular formula: C34H28N4O2·HCl. Mole weight: 561.07. | |
AMI-1 Quick inquiry Where to buy Suppliers range | AMI-1 is a cell-permeable inhibitor which inhibits protein arginine N-methyltransferase (PRMT) activity with IC50 of 8.81 μM for PRMT1 and IC50 of 3.04 μM for Hmt1p in vitro. MI-1 does not compete for the AdoMet (S-adenosyl-L-methionine; SAM) binding site and exhibits minimal effects on both SET (Sub39H1, Suv39H2, SET7) and non-SET (DOT1) lysine N-methyltransferases. Furthermore, AMI-1 prevents in vivo arginine methylation of cellular proteins and can modulate nuclear receptor-regulated transcription from estrogen and androgen response elements, thus operating as a brake on certain hormone actions. Synonyms: 7,7'-(Carbonyldiimino)bis[4-hydroxy-2-naphthalenesulfonic acid] disodium salt; 5,5'-Dihydroxy-2,2'-dinaphthylcarbamide-7,7'-disulfonic acid disodium salt; 6,6'-Ureylenebis(1-naphthol-3-sulfonic acid) disodium salt; 7,7'-Ureylenebis(4-hydroxy-2-naphthalenesulfonic acid) disodium salt; Carbonyl J disodium salt; I Acid Urea disodium salt; N,N'-Bis(5-hydroxy-7-sulfo-2-naphthyl)urea disodium salt; N,N'-Bis(7-sulfo-5-hydroxy-2-naphthyl)urea disodium salt; N,N'-Bis[1-hydroxy-3-sulfonaphthyl(6)]urea disodium salt; N,N'-Bis[1-oxy-3-sulfonaphthyl(6)]urea disodium salt; AMI-1 sodium salt; AMI 1; AMI1; J Acid Urea disodium salt. Grades: ≥98%. CAS No. 20324-87-2. Molecular formula: C21H14N2Na2O9S2. Mole weight: 548.45. | |
AMI-1 Quick inquiry Where to buy Suppliers range | Potent, cell permeable and specific protein arginine N-methyltransferase 1 (PRMT1) inhibitor (IC50 = 8.8uM). Does not compete for the AdoMet (S-adenosyl-L-methionine; SAM) binding site. Blocks peptide substrate binding. HIV-1 RT polymerase inhibitor (IC50 = 5.0uM). Group: Biochemicals. Alternative Names: Arginine N-methyltransferase inhibitor-1. Grades: Highly Purified. CAS No. 160994-87-6, 134-47-4. Pack Sizes: 5mg, 25mg. Molecular Formula: C21H12N2O9S2Na4. US Biological Life Sciences. | Worldwide |
AMI-193 Quick inquiry Where to buy Suppliers range | AMI-193 has been found to be a selective 5-HT antagonist and could be also used as a starting reagent in some pharmaceutical synthesis. Synonyms: Spiramide; R 5808; R-5808; R5808; 8-[3-(4-Fluorophenoxy)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]-decanone. Grades: ≥99% by HPLC. CAS No. 510-74-7. Molecular formula: C22H26FN3O2. Mole weight: 383.46. | |
AMI-193 Quick inquiry Where to buy Suppliers range | AMI-193. Group: Biochemicals. Grades: Purified. CAS No. 510-74-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
AMI-1 (Arginine N-methyltransferase Inhibitor-1) (Sodium Salt) Quick inquiry Where to buy Suppliers range | PRMT1,3,4 & 6 Inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
AMI-1 sodium salt Quick inquiry Where to buy Suppliers range | Cas No. 20324-87-2. | |
Amicarbalide Quick inquiry Where to buy Suppliers range | Amicarbalide. Group: Heterocyclic Organic Compound. Alternative Names: Amicarbalide. Grades: 96%. CAS No. 3459-96-9. Molecular formula: C15H16N6O. Mole weight: 296.332. IUPAC Name: 1,3-bis(3-carbamimidoylphenyl)urea. Exact Mass: 296.13900. EC Number: 222-402-7. Density: 1.4g/cm3. SMILES: C1=CC (=CC (=C1)NC (=O)NC2=CC=CC (=C2)C (=N)N)C (=N)N. InChIKey: KRUVSRGJKCHYMY-UHFFFAOYSA-N. H-Bond Donor: 6. H-Bond Acceptor: 5. | |
Amicarbazone Quick inquiry Where to buy Suppliers range | The phenotypic responses of sensitive plants exposed to amicarbazone include chlorosis, stunted growth, tissue necrosis, and death. Its efficacy as both a foliar- and root-applied herbicide suggests that absorption and translocation of this compound is very rapid. As a result, its efficacy is susceptible to the most common form of resistance to PSII inhibitors. Nonetheless, amicarbazone has a good selectivity profile and is a more potent herbicide than atrazine, which enables its use at lower rates than those of traditional photosynthetic inhibitors. Synonyms: BAY314666; BAY-MKH 3586; BAY 314666; BAY-MKH3586. Grades: >98%. CAS No. 129909-90-6. Molecular formula: C10H19N5O2. Mole weight: 241.29. | |
Amicarbazone Quick inquiry Where to buy Suppliers range | Amicarbazone. Uses: For analytical and research use. Group: Pesticides & Metabolites; Pesticides & Metabolites. CAS No. 129909-90-6. IUPAC Name: 4-amino-N-tert-butyl-5-oxo-3-propan-2-yl-1,2,4-triazole-1-carboxamide. Molecular formula: C10H19N5O2. Mole weight: 241.29. Catalog: APS129909906. SMILES: CC(C)C1=NN(C(=O)NC(C)(C)C)C(=O)N1N. Format: Neat. Shipping: Room Temperature. | |
Amicarbazone 100 μg/mL in Acetonitrile Quick inquiry Where to buy Suppliers range | Amicarbazone 100 μg/mL in Acetonitrile. Uses: For analytical and research use. Group: Pesticides & Metabolites; Pesticides & Metabolites. CAS No. 129909-90-6. Pack Sizes: 1ML. IUPAC Name: 4-amino-N-tert-butyl-5-oxo-3-propan-2-yl-1,2,4-triazole-1-carboxamide. Molecular formula: C10H19N5O2. Mole weight: 241.29. Catalog: APS129909906A. SMILES: CC(C)C1=NN(C(=O)NC(C)(C)C)C(=O)N1N. Format: Single Solution. Shipping: Room Temperature. | |
Amicarbazone-desamino Quick inquiry Where to buy Suppliers range | Amicarbazone-desamino. Uses: For analytical and research use. Group: Pesticides & Metabolites; Pesticides & Metabolites. Catalog: APS005737. Format: Neat. Product Type: Metabolite. | |
Amicarbazone Impurity 1 Quick inquiry Where to buy Suppliers range | An impurity of Amicarbazone. Synonyms: N-(1,1-Dimethylethyl)-2,5-dihydro-3-(1-methylethyl)-5-oxo-1H-1,2,4-triazole-1-carboxamide. Grades: > 95%. CAS No. 889062-05-9. Molecular formula: C10H18N4O2. Mole weight: 226.28. | |
Amicarbazone Impurity 2 Quick inquiry Where to buy Suppliers range | An impurity of Amicarbazone. Synonyms: N-(1,1-Dimethylethyl)-2,5-dihydro-3-(1-hydroxy-1-methylethyl)-5-oxo-1H-1,2,4-triazole-1-carboxamide. Grades: > 95%. CAS No. 889062-06-0. Molecular formula: C10H18N4O3. Mole weight: 242.28. | |
Amicenomycin A Quick inquiry Where to buy Suppliers range | It is produced by the strain of Streptomyces sp. MJ384-46F6. It has anti-gram-positive bacterial activity. Molecular formula: C43H56O16. Mole weight: 828.89. | |
Amicenomycin B Quick inquiry Where to buy Suppliers range | It is produced by the strain of Streptomyces sp. MJ384-46F6. It has weak anti-gram-positive bacterial activity. Molecular formula: C43H56O16. Mole weight: 828.89. |