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Alvimopan impurity E. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-methyl 2-benzyl-3-((3S,4S)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanoate hydrochloride. Molecular Formula: C24H32ClNO3. Mole Weight: 417.97. Catalog: APB02523.
Alvimopan impurity F
Alvimopan impurity F. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-methyl 2-benzyl-3-((3S,4S)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanoate. Molecular Formula: C24H31NO3. Mole Weight: 381.51. Catalog: APB02524.
Alvimopan impurity G
Alvimopan impurity G. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-((S)-2-benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanamido)acetic acid. Molecular Formula: C25H32N2O4. Mole Weight: 424.53. Catalog: APB02522.
Alvimopan impurity H
Alvimopan impurity H. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-((R)-2-benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanamido)acetic acid. Molecular Formula: C25H32N2O4. Mole Weight: 424.53. Catalog: APB02521.
Alvimopan impurity I
Alvimopan impurity I. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-((R)-2-benzyl-3-((3S,4S)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanamido)acetic acid. Molecular Formula: C25H32N2O4. Mole Weight: 424.53. Catalog: APB02520.
Alvimopan impurity J
Alvimopan impurity J. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-((S)-2-benzyl-3-((3S,4S)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanamido)acetic acid. Molecular Formula: C25H32N2O4. Mole Weight: 424.53. Catalog: APB02519.
Alvimopan Metabolite
A metabolite of Alvimopan. Synonyms: ADL 08-0011. Grades: > 95%. CAS No. 156130-41-5. Molecular formula: C23H29NO3. Mole weight: 367.49.
Alvimopan monohydrate
The monohydrate salt form of Alvimopan could be commonly used in postoperative recovery of gastrointestinal for acting as a mu-opioid receptor (PAM-OR) antagonist with IC50: 1.7 nM. Uses: The monohydrate salt form of alvimopan could be commonly used in postoperative recovery of gastrointestinal for acting as a mu-opioid receptor (pam-or) antagonist. Synonyms: UNII-28LAR2REDG; 28LAR2REDG; DTXSID30160641; 3078AH; 2-[[(2S)-2-benzyl-3-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]propanoyl]amino]acetic acid;hydrate. Grades: 98%. CAS No. 1383577-62-5. Molecular formula: C25H34N2O5. Mole weight: 442.55.
Alvirin impurity
Alvirin impurity. Uses: For analytical and research use. Group: Impurity standards. CAS No. 142047-93-6. Molecular Formula: C20H28ClNO. Mole Weight: 333.9. Catalog: APB142047936.
Alvocidib
Alvocidib is a synthetic N-methylpiperidinyl chlorophenyl flavone compound. As an inhibitor of cyclin-dependent kinase, alvocidib induces cell cycle arrest by preventing phosphorylation of cyclin-dependent kinases (CDKs) and by down-regulating cyclin D1 and D3 expression, resulting in G1 cell cycle arrest and apoptosis. Uses: For research used only. Synonyms: Flavopiridol; HMR 1275. HMR1275. HMR-1275. Grades: 0.98. CAS No. 146426-40-6. Molecular formula: C21H20ClNO5. Mole weight: 401.84.
ALW-II-41-27
ALW-II-41-27 is an effective inhibitor of EPH family kinases that has been found to be related to lung cancers. IC50: 11 nM to EPHA2. Uses: Alw-ii-41-27 is an effective inhibitor of eph family kinases that is found to be related to lung cancers. Synonyms: ALW-II-41-27; ALW II-41-27; ALWII-41-27; ALW-II-4127; ALW II-4127; ALWII-4127; MLS002232274; CHEMBL556140; DTXSID80655254; BDBM163701. Grades: 98%. CAS No. 1186206-79-0. Molecular formula: C32H32F3N5O2S. Mole weight: 607.69.
ALW-II-41-27
ALW-II-41-27 is a Eph receptor tyrosine kinase inhibitor. pharmacologic inhibition of EPHA2 by the small-molecule inhibitor ALW-II-41-27 decreased both survival and proliferation of erlotinib-resistant tumor cells and inhibited tumor growth in vivo. ALW-II-41-27 was also effective in decreasing viability of cells with acquired resistance to the third-generation EGFR TKI AZD9291. Collectively, these data define a role for EPHA2 in the maintenance of cell survival of TKI-resistant, EGFR-mutant lung cancer and indicate that EPHA2 may serve as a useful therapeutic target in TKI-resistant tumors. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ALW-II-41-27; ALW II-41-27; ALWII-41-27; ALW-II-4127; ALW II-4127; ALWII-4127. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1186206-79-0. Molecular formula: C32H32F3N5O2S. Mole weight: 607.7. Purity: >98%. IUPACName: N-(5-((4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)carbamoyl)-2-methylphenyl)-5-(thiophen-2-yl)nicotinamide. Canonical SMILES: O=C(NC1=CC(C(NC2=CC=C(CN3CCN(CC)CC3)C(C(F)(F)F)=C2)=O)=CC=C1C)C4=CN=CC(C5=CC=CS5)=C4. Product ID: ACM1186206790. Alfa Chemistry ISO 9001:2015 Certified.
ALX 40-4C
ALX 40-4C is a small peptide inhibitor of the chemokine receptor CXCR4, which inhibits the binding of SDF-1 to CXCR4 and inhibits the replication of X4 strain HIV-1. It is also an APJ receptor antagonist. Synonyms: Ac-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-NH2; N-acetyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-argininamide; Ac-(D-Arg)9-NH2; ALX40-4C; N-alpha-Acetyl-nona-D-arginine amide. Grades: ≥95%. CAS No. 143413-49-4. Molecular formula: C56H113N37O10. Mole weight: 1464.74.
ALX 40-4C acetate
ALX 40-4C acetate is a small peptide inhibitor of the chemokine receptor CXCR4. It inhibits SDF-1 from binding CXCR4 with a Ki of 1 μM, and suppresses the replication of X4 strains of HIV-1. Molecular formula: C58H117N37O12. Mole weight: 1524.79.
ALX 40-4C Trifluoroacetate
ALX 40-4C Trifluoroacetate is a small peptide inhibitor of the chemokine receptor CXCR4, which inhibits the binding of SDF-1 to CXCR4 and inhibits the replication of X4 strain HIV-1. It is also an APJ receptor antagonist. Synonyms: Ac-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-NH2.TFA; N-acetyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-argininamide trifluoroacetic acid; ALX 40-4C TFA. Grades: >98%. Molecular formula: C56H113N37O10.C2HF3O2. Mole weight: 1578.76.
ALX 5407 hydrochloride
The hydrochloride salt form of ALX 5407, which has been found to be an inhibitor of the glycine transporter GlyT1 and could probably be useful in some neuropsychiatric disorders. Synonyms: ALX 5407 hydrochloride; ALX-5407 hydrochloride; ALX5407 hydrochloride; N-[(3R)-3-([1,1'-Biphenyl]-4-yloxy)-3-(4-fluorophenyl)propyl]-N-methylglycine hydrochloride. Grades: ≥98% by HPLC. CAS No. 200006-08-2. Molecular formula: C24H24FNO3.HCl. Mole weight: 429.92.
ALX 5407 hydrochloride
ALX 5407 hydrochloride. Group: Biochemicals. Alternative Names: N-[(3R)-3-([1,1'-Biphenyl]-4-yloxy)-3-(4-fluorophenyl)propyl]-N-methylglycine hydrochloride. Grades: Highly Purified. CAS No. 200006-08-2. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C24H25ClFNO3. US Biological Life Sciences.
Worldwide
ALX-5407 hydrochloride
ALX-5407 ((R)-NFPS) hydrochloride is a selective and orally active glycine transporter GlyT1 inhibitor with an IC 50 value of 3 nM. ALX-5407 hydrochloride can be used the research of N-methyl-D-aspartate-receptor function and schizophrenia [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-NFPS hydrochloride. CAS No. 200006-08-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-10711A.
Alyssin
Alyssin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-ISOTHIOCYANATO-5-(METHYLSULFINYL)-PENTANE;ALYSSIN;ALYSSIN SULFONE;5-methylsulfinylpentylimino(thioxo)methane. Product Category: Heterocyclic Organic Compound. Appearance: liquid. CAS No. 646-23-1. Molecular formula: C7H13NOS2. Mole weight: 191.31. Purity: 0.96. IUPACName: 1-isothiocyanato-5-methylsulfinylpentane. Canonical SMILES: CS(=O)CCCCCN=C=S. Density: 1.14g/cm³. Product ID: ACM646231. Alfa Chemistry ISO 9001:2015 Certified. Categories: Alyssum.
Alyteserin-1a
Alyteserin-1a is an antimicrobial peptide produced by Alytes obstetricans (European midwife toad). It has antibacterial activity against Gram-negative bacterium such as E. coli (MIC=25 μM). Synonyms: Gly-Leu-Lys-Asp-Ile-Phe-Lys-Ala-Gly-Leu-Gly-Ser-Leu-Val-Lys-Gly-Ile-Ala-Ala-His-Val-Ala-Asn-NH2. Grades: >96%. CAS No. 1159767-77-7. Molecular formula: C104H176N30O27. Mole weight: 2278.74.
Alyteserin-1b
Alyteserin-1b is an antimicrobial peptide produced by Alytes obstetricans (European midwife toad). It has antibacterial activity against Gram-negative bacterium such as E. coli (MIC=25 μM). Synonyms: Gly-Leu-Lys-Glu-Ile-Phe-Lys-Ala-Gly-Leu-Gly-Ser-Leu-Val-Lys-Gly-Ile-Ala-Ala-His-Val-Ala-Asn-NH2. Grades: ≥97%. CAS No. 1159767-78-8. Molecular formula: C105H178N30O27. Mole weight: 2292.76.
Alyteserin-1c
Alyteserin-1c is an antimicrobial peptide produced by Alytes obstetricans (European midwife toad). It has antibacterial activity against Gram-negative bacterium such as E. coli (MIC=25 μM). Synonyms: Gly-Leu-Lys-Glu-Ile-Phe-Lys-Ala-Gly-Leu-Gly-Ser-Leu-Val-Lys-Gly-Ile-Ala-Ala-His-Val-Ala-Ser-NH2. Grades: 98%. CAS No. 1159767-79-9. Molecular formula: C104H177N29O27. Mole weight: 2265.74.
Alyteserin-1d
Alyteserin-1d is an antimicrobial peptide produced by Alytes obstetricans (European midwife toad). It has antibacterial activity. Synonyms: Gly-Leu-Lys-Asp-Ile-Phe-Lys-Ala-Gly-Leu-Gly-Ser-Leu-Val-Lys-Asn-Ile-Ala-Ala-His-Val-Ala-Asn-NH2. Grades: >98%. CAS No. 1159767-80-2. Molecular formula: C106H179N31O28. Mole weight: 2335.79.
Alyteserin-1Ma
Alyteserin-1Ma is an antimicrobial peptide produced by Alytes maurus (Midwife toad). It has antibacterial and antifungal activity. It is active against Gram-negative bacterium: Escherichia coli NCTC 10418 (MIC=214 μM) and Gram-positive bacterium: Staphylococcus aureus NCTC 10788 (MIC=214 μM). Synonyms: Gly-Phe-Lys-Glu-Val-Leu-Lys-Ala-Asp-Leu-Gly-Ser-Leu-Val-Lys-Gly-Ile-Ala-Ala-His-Val-Ala-Asn-NH2. Grades: >98%. Molecular formula: C106H178N30O29. Mole weight: 2336.77.
Alyteserin-1Mb
Alyteserin-1Mb is an antimicrobial peptide produced by Alytes maurus (Midwife toad). It has antibacterial and antifungal activity. It is active against Gram-negative bacterium: Escherichia coli NCTC 10418 (MIC=217 μM) and Gram-positive bacterium: Staphylococcus aureus NCTC 10788 (MIC=434 μM). Synonyms: Gly-Phe-Lys-Glu-Val-Leu-Lys-Ala-Gly-Leu-Gly-Ser-Leu-Val-Lys-Gly-Ile-Pro-Ala-His-Val-Ala-Asn-NH2. Grades: ≥97%. Molecular formula: C106H178N30O27. Mole weight: 2304.77.
Alyteserin-2a
Alyteserin-2a is an antimicrobial peptide produced by Alytes obstetricans (European midwife toad). It has antibacterial activity against Gram-positive bacterium such as Staphylococcus aureus (MIC=50 μM). Synonyms: Ile-Leu-Gly-Lys-Leu-Leu-Ser-Thr-Ala-Ala-Gly-Leu-Leu-Ser-Asn-Leu-NH2. Grades: ≥96%. CAS No. 1159767-81-3. Molecular formula: C72H131N19O20. Mole weight: 1582.95.
Alyteserin-2b
Alyteserin-2b is an antimicrobial peptide produced by Alytes obstetricans (European midwife toad). It has antibacterial activity. Synonyms: Ile-Leu-Gly-Ala-Ile-Leu-Pro-Leu-Val-Ser-Gly-Leu-Leu-Ser-Asn-Lys-Leu-NH2. Grades: >98%. CAS No. 1159767-82-4. Molecular formula: C81H146N20O20. Mole weight: 1720.18.
Alyteserin-2c
Alyteserin-2c is an antimicrobial peptide produced by Alytes obstetricans (European midwife toad). It has antibacterial activity. Synonyms: Ile-Leu-Gly-Ala-Ile-Leu-Pro-Leu-Val-Ser-Gly-Leu-Leu-Ser-Ser-Lys-Leu-NH2. Grades: >98%. CAS No. 1159767-83-5. Molecular formula: C80H145N19O20. Mole weight: 1693.15.
Alyteserin-2Ma
Alyteserin-2Ma is an antimicrobial peptide produced by Alytes maurus (Midwife toad). It has antibacterial and antifungal activity. It is active against Gram-negative bacterium: Escherichia coli NCTC 10418 (MIC=38.4 μM) and Gram-positive bacterium: Staphylococcus aureus NCTC 10788 (MIC=9.5 μM). It only inhibits C. albicans at very high concentration of 150 uM. Synonyms: Phe-Ile-Gly-Lys-Leu-Ile-Ser-Ala-Ala-Ser-Gly-Leu-Leu-Ser-His-Leu-NH2. Grades: ≥97%. Molecular formula: C76H128N20O19. Mole weight: 1625.98.
Alyteserin-2Mb
Alyteserin-2Mb is an antimicrobial peptide produced by Alytes maurus (Midwife toad). It has antibacterial and antifungal activity. It is active against Gram-positive bacterium: Staphylococcus aureus NCTC 10788 (MIC=19.3 μM). It only inhibits C. albicans at very high concentration of 310 uM. Synonyms: Ile-Leu-Gly-Ala-Ile-Ile-Pro-Leu-Val-Ser-Gly-Leu-Leu-Ser-His-Leu-NH2. Grades: ≥96%. Molecular formula: C77H135N19O18. Mole weight: 1615.04.
Alytesin
Alytesin. Group: Biochemicals. Grades: Purified. CAS No. 31078-12-3. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Alytesin
Alytesin is an amphibian bombesin-like peptide originally isolated from the skin of the European amphibian, alytes obstetricans. It has biological activity very similar to bombesin. It could cause rat uterine contraction, intestinal contraction, gastric acid secretion and hypertension in vivo in the dog. It also adjusts thermoregulation following central administration in vivo. Synonyms: Alytesin; 31078-12-3; CID 16131139; XGRLGTQWAVGHLM; Alytesin (trifluoroacetate salt); BDBM85497; DTXSID40185027; Pgly-arg-leu-gly-thr-gln-trp-ala-val-gly-his-leu-met-NH2; AKOS024456835; AKOS040764257; CAS_31078-12-3; HY-103276; CS-0026803; J-018236. CAS No. 31078-12-3. Molecular formula: C68H106N22O17S. Mole weight: 1535.78.
ALZ-801
ALZ-801 is a novel and orally available prodrug of tramiprosate that is undergoing a clinical trial for the treatment of Alzheimer's disease (AD). Compared to tramiprosate, ALZ-801 improves some critical properties including tolerability, pharmacokinetic and pharmacodynamic profile, as well as metabolic stability. It inhibits the toxic amyloid oligomers formation associated with AD, which is a discovery of new mechanism of AD prevention. Uses: Prevention of alzheimer's disease (ad). Synonyms: ALZ-801; ALZ 801; ALZ801.
Al/Zn/Mg/Cu Alloy, 50g Chips
Al/Zn/Mg/Cu Alloy, 50g Chips. Uses: For analytical and research use. Group: Aluminium base; metal alloys. Pack Sizes: 50G. Catalog: APS00698. Format: Chips. Shipping: Room Temperature.
AM-001
AM-001 is a non-competitive inhibitor of Epac1 that blocks the activation of Rap1, a downstream effector of Epac1, in cultured cells. AM-001 can be used in heart disease-related research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 340817-81-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-126133.
AM-0466
AM-0466 is a potent and selective Nav1.7 inhibitor (IC50 = 0.020 nM). It exhibited an effective activity in a NaV1.7-dependent model of histamine-induced pruritus (itch) and also in a capsaicin-induced nociception model of pain. Synonyms: AM 0466; AM0466. CAS No. 1642113-59-4. Molecular formula: C27H19F3N4O4S. Mole weight: 552.52.
AM-0687
This active molecular is a selective PI3Kδ inhibitor. PI3Kδ is hyperactivated in B-cell malignancies and plays a vital role in the B-cell receptor pathway. AM-0687 has Cellular potency: pAKT IC50 = 0.7 nM; HWB, u (pAKT) IC 50 = 4.6 nM. AM-0687 shows excellent potency and selectivity profile in biochemical and cellular assays. Uses: Cancer drug candidate. Synonyms: AM-0687; AM 0687; AM0687. 2 - ((1S) - 1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-6-fluoro - N - methyl-3-(2-pyridinyl)-4-quinolinecarboxamide. Grades: 98%. CAS No. 1259522-94-5. Molecular formula: C23H19FN8O. Mole weight: 442.46.
AM 0902
AM 0902 is an effective and selective TRPA1 antagonist and has been found to exhibit activities in biological pathways associated with pain. Synonyms: AM-0902; AM 0902; AM0902. 1-[[3-[2-(4-Chlorophenyl)ethyl]-1,2,4-oxadiazol-5-yl]methyl]-1,7-dihydro-7-methyl-6H-purin-6-one. Grades: ≥98% by HPLC. CAS No. 1883711-97-4. Molecular formula: C17H15ClN6O2. Mole weight: 370.79.
AM095
AM095 is a selective LPA 1 receptor antagonist. The IC 50 for AM095 antagonism of LPA-induced calcium flux of human or mouse LPA 1 -transfected CHO cells is 0.025 and 0.023 μM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1345614-59-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-16039.
AM095
AM095, an effective LPA1 receptor antagonist, has been found to decrease dermal fibrosis caused by attenuates bleomycin. IC50: 0.98 uM and 0.73 uM for human and mouse LPA1 respectively. Synonyms: AM095 (free acid); AM-095; AM 095. Grades: 98%. CAS No. 1228690-36-5. Molecular formula: C27H24N2O5. Mole weight: 456.49.
AM095 free acid
AM095 (free acid) is a potent LPA1 receptor antagonist with IC 50 values of 0.98 and 0.73 μM for recombinant human or mouse LPA1 respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1228690-36-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-16040.
AM095 sodium
AM095 is a selective LPA1 receptor antagonist. The IC50 for AM095 antagonism of LPA-induced calcium flux of human or mouse LPA1-transfected CHO cells is 0.025 and 0.023 μM, respectively. Synonyms: AM-095 sodium; AM 095 sodium. Grades: >98%. CAS No. 1345614-59-6. Molecular formula: C27H23N2NaO5. Mole weight: 478.48.
AM103
AM 103 is a potent and selective FLAP inhibitor, with an IC 50 value of 4.2 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1147872-22-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14163.
AM-114
AM 114 is an inhibitor of chymotrypsin-like activity of the 20S proteasome. In addition, AM-114 shows anticancer activity, It can inhibit cell growth in human colon cancer HCT116 p53+/+ cells. Uses: Anticancer. Synonyms: AM-114; AM 114; AM114; Proteasome Inhibitor IX; ( (1Z, 1'Z)- (1-methyl-4-oxopiperidine-3, 5-diylidene)bis (methanylylidene))bis (4, 1-phenylene))diboronic acid. Grades: 98%. CAS No. 856849-35-9. Molecular formula: C20H21B2NO5. Mole weight: 377.01.
AM 1172
AM 1172, an AEA analogue, has been found to be an anandamide uptake inhibitor as well as a cannabinoid receptor partial agonist. Synonyms: AM 1172; AM1172; AM-1172; N-(5Z,8Z,11Z,14Z)-5,8,11,14-eicosatetraen-1-yl-4-hydroxybenzamide. Grades: ≥98% by HPLC. CAS No. 251908-92-6. Molecular formula: C27H39NO2. Mole weight: 409.60.
AM 1172
AM 1172. Group: Biochemicals. Grades: Purified. CAS No. 251908-92-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
AM 12
AM 12 is a TRPC5 inhibitor with an IC50 value of 0.28 μM, which exhibits some selectivity for TRPC5 over TRPC2, 3 and 4. Synonyms: 2-(2-Bromophenyl)-3,5,7-trihydroxy-4H-chromen-4-one. Grades: ≥97%. Molecular formula: C15H9BrO5. Mole weight: 349.14.
AM1241
AM-1241 is a selective cannabinoid CB2 receptor agonist with Ki of 3.4 nM, exhibits 82-fold selectivity over CB1 receptor. Synonyms: AM 1241; AM-1241; (1-(Methylpiperidin-2-ylmethyl)-3-(2-iodo-5-nitrobenzoyl)indole); (R,S)-3-(2-Iodo-5-nitrobenzoyl)-1-(1-methyl-2-piperidinylmethyl)-1H-indole. Grades: >98%. CAS No. 444912-48-5. Molecular formula: C22H22IN3O3. Mole weight: 503.33.
AM-156
Prostanoid GD(2) is released from mast cells in response to allergen challenge. AM156 is a selective prostanoid DP(2) receptor antagonist and it inhibits sneezing and nasal rubs in a model of allergic rhinitis. It can also inhibits pulmonary inflammation and mucus hypersecretion induced by chronic inhalation of house dust mite. AM156 may be have beneficial effects for treatment of allergic rhinitis and asthma in the future. Uses: Allergic rhinitis and asthma. Synonyms: AM-156; AM 156; AM156; UNII-5V9HJQ1Y75;sodium 2-(2'-((N-ethylcyclopropanecarboxamido)methyl)-6-methoxy-4'-(trifluoromethyl)-[1,1'-biphenyl]-3-yl)acetate;1175525-98-0 (AM-156 free acid). Grades: 98%. CAS No. 1224977-85-8. Molecular formula: C23H23F3NNaO4. Mole weight: 457.42.
AM-156 sodium
AM-156 is a bio-active chemical and detailed information has not been published yet. Synonyms: AM-156 sodium; AM 156 sodium; AM156 sodium; sodium 2-(2'-((N-ethylcyclopropanecarboxamido)methyl)-6-methoxy-4'-(trifluoromethyl)-[1,1'-biphenyl]-3-yl)acetate,UNII-5V9HJQ1Y75,1175525-98-0 (AM-156 free acid). Grades: 98%. CAS No. 1175525-98-0. Molecular formula: C23H23F3NNaO4. Mole weight: 457.42.
AM 1714
AM 1714, a synthetic cannabimimetic indole derivative, is a potent and selective agonist for the cannabinoid receptor. Uses: A potent and selective agonist for the cannabinoid receptor. Synonyms: AM-1714; AM 1714; AM1714; UNII-E3OY6PCU04; 6H-Dibenzo(b,d)pyran-6-one, 3-(1,1-dimethylheptyl)-1,9-dihydroxy-. Grades: ≥98%. CAS No. 335371-37-4. Molecular formula: C22H26O4. Mole weight: 354.44.
AM-206
AM-206 is a bio-active chemical but no detailed data has been published yet. Synonyms: AM-206; AM 206; AM206; 3-Pyridineacetic acid, 5- (2- ( (ethyl ( (phenylmethoxy) carbonyl) amino) methyl) -4- (trifluoromethyl) phenyl) -, sodium salt (1:1); UNII-NCZ7ZWF0CR;1219935-54-2 (AM-206 free acid). Grades: 98%. CAS No. 1224977-86-9. Molecular formula: C25H22F3N2NaO4. Mole weight: 494.44.
AM-206 sodium
AM-206 is a bio-active chemical but no detailed data has been published yet. Synonyms: AM-206; AM 206; AM206; UNII-NCZ7ZWF0CR;(5-(2-((N-((Benzyl)oxycarbonyl)-N-ethylamino)methyl)-4-trifluoromethylphenyl)pyridin-3-yl)acetic acid. Grades: 98%. CAS No. 1219935-54-2. Molecular formula: C25H23F3N2O4. Mole weight: 472.46.
AM-2099
AM-2099 is a potent and selective inhibitor of voltage-gated sodium channel Nav1.7 (IC50 = 0.16 μM) with excellent selectivity against hNav1.5 (IC50 > 30 uM). Synonyms: 4-[2-methoxy-4-(trifluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)quinazoline-7-sulfonamide; AM-2099; AM2099; AM 2099. CAS No. 1443373-17-8. Molecular formula: C19H13F3N4O3S2. Mole weight: 466.46.
AM-211
This active molecular is a potent Prostaglandin D2 receptor antagonists and has been in phase I clinical trials for both COPD (chronic obstructive pulmonary disease) and asthma, but no recent results has been published. Uses: Chronic obstructive pulmonary disease(copd) and asthma. Synonyms: AM-211; AM 211; AM211; 2-(2'-((3-benzyl-1-ethylureido)methyl)-6-methoxy-4'-(trifluoromethyl)-[1,1'-biphenyl]-3-yl)acetic acid,1263077-74-2 (AM-211 sodium). Grades: 98%. CAS No. 1175526-27-8. Molecular formula: C27H27F3N2O4. Mole weight: 500.51.
AM-211 sodium
This active molecular is a potent Prostaglandin D2 receptor antagonists and has been in phase I clinical trials for both COPD (chronic obstructive pulmonary disease) and asthma, but no recent results has been published. Uses: Chronic obstructive pulmonary disease(copd) and asthma. Synonyms: UNII-8SV621U288;1175526-27-8(Free acid); AM-211 sodium; AM 211 sodium; AM211 sodium. Grades: 98%. CAS No. 1263077-74-2. Molecular formula: C27H26F3N2O4Na. Mole weight: 522.50.
AM-2159
AM-2159 is a bio-active chemical, but no detailed information has been published yet. Synonyms: AM-2159; AM 2159; AM2159; N6-((4-chlorophenyl)methyl)-N6-methyl- 2,4,6-Quinazolinetriamine. Grades: 98%. CAS No. 83654-06-2. Molecular formula: C16H16ClN5. Mole weight: 313.78.
AM-2233
AM-2233. Group: Biochemicals. Alternative Names: (2-Iodophenyl)[1-[(1-methyl-2-piperidinyl)methyl]-1H-indol-3-yl]methanone; 1-[(N-Methyl-2-piperidinyl)methyl]-3-(2-iodobenzoyl)-1H-indole. Grades: Highly Purified. CAS No. 444912-75-8. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C22H23IN2O. US Biological Life Sciences.
Worldwide
AM-2394
AM-2394 is a selective Glucokinase agonist (GKA), It activates GK with an EC50 value of 60 nM. AM-2394 increases the affinity of GK for glucose by approximately 10-fold. It shows moderate clearance and good oral bioavailability in animal models, and lowers glucose excursion following an oral glucose tolerance test in an ob/ob mouse model of diabetes. Uses: Diabetes. Synonyms: AM-2394; AM 2394; AM2394; 1-(6'-(2-hydroxy-2-methylpropoxy)-4-((5-methylpyridin-3-yl)oxy)-[3,3'-bipyridin]-6-yl)-3-methylurea. Grades: 98%. CAS No. 1442684-77-6. Molecular formula: C22H25N5O4. Mole weight: 423.47.
AM251
AM251 is a selective cannabinoid 1 ( CB1 ) receptor antagonist with an IC 50 of 8 nM. AM251 also acts as a potent GPR55 agonist with an EC 50 of 39 nM [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 183232-66-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15443.
AM251
AM251 block the inhibitory effects of endocannabinoids and synthetic cannabinoid agonists on transmitter release through an action at presynaptic cannabinoid 1 receptors in brain. Synonyms: AM251; AM 251; AM-251. Grades: >98%. CAS No. 183232-66-8. Molecular formula: C22H21Cl2IN4O. Mole weight: 555.24.
AM 251
Inhibitor of CB1 receptors. Group: Biochemicals. Alternative Names: 1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide. Grades: Highly Purified. CAS No. 183232-66-8. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
AM281
AM281 is a selective CB1 receptor antagonist with an IC 50 of 9.91 nM. AM281 inhibits CB2 receptor with an IC 50 of 13000 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 202463-68-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13505.
AM 281
AM 281 has been found to be a CB1 selective receptor cannabinoid antagonist. Synonyms: AM281; AM 281; AM-281; 1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-4-morpholinyl-1H-pyrazole-3-carboxamide. Grades: ≥99% by HPLC. CAS No. 202463-68-1. Molecular formula: C21H19Cl2IN4O2. Mole weight: 557.22.
AM 281
AM 281. Group: Biochemicals. Alternative Names: 1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-4-morpholinyl-1H-pyrazole-3-carboxamide. Grades: Highly Purified. CAS No. 202463-68-1. Pack Sizes: 1mg. Molecular Formula: C21H19Cl2IN4O2, Molecular Weight: 557.21. US Biological Life Sciences.
Worldwide
Am3102
Am3102. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AM3102;(Z)-(R)-N-((2-Hydroxy-1-methyl)ethyl)-9-octadecenamide. Product Category: Heterocyclic Organic Compound. Appearance: A crystalline solid. CAS No. 213182-22-0. Molecular formula: C21H41NO2. Mole weight: 339.56. Density: 0.911. Product ID: ACM213182220. Alfa Chemistry ISO 9001:2015 Certified. Categories: AM302.
AM3102
AM-3102 is an Oleoyl ethanolamide (OEA) analog that stimulates PPARα transcriptional activity with an EC50 value of 100 nM and prolongs feeding latency. The biological effects of OEA are terminated by N-acylethanolamine-hydrolyzing acid amidase and fatty-acid amide hydrolase. AM3102 demonstrates weak affinity for the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors with Ki values of 33 and 26 μM, respectively. Synonyms: KDS-5104; AM-3102; AM 3102; Methyl oleoylethanolamide. Grades: ≥98%. CAS No. 213182-22-0. Molecular formula: C21H41NO2. Mole weight: 339.6.
AM3102
AM3102 is an oleoylethanolamide (OEA) analog. AM3102 is an endogenous high-affinity PPAR-alpha agonist. AM3102 resists enzymatic hydrolysis, activates PPAR-alpha with high potency in vitro, and persistently reduces feeding when administered in vivo either parenterally or orally [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 213182-22-0. Pack Sizes: 5 mg. Product ID: HY-129683.
AM-36
AM-36 is a potent blocker of batrachotoxinin (BTX)-sensitive Na+ channel binding in rat brain homogenates with an IC50 of 0.28 microM. As a unique neuroprotective agent with anti-oxidant activity, in neuronal cell cultures, AM-36 inhibited toxicity induced by N-methyl-D-aspartate (NMDA) and the sodium channel opener veratridine and, in addition, inhibited veratridine-induced apoptosis. Synonyms: 2,6-ditert-butyl-4-[[4-[2-(4-chlorophenyl)-2-hydroxyethyl]piperazin-1-yl]methyl]phenol; AM-36; AM 36; AM36; UNII-08OBY024NY; SCHEMBL12311270; CNSB 002; CNSB-002; CNSB002. Grades: >98%. CAS No. 199467-52-2. Molecular formula: C27H39ClN2O2. Mole weight: 459.06.
AM 374
AM 374 is an fatty acid amide hydrolase (FAAH) inhibitor. AM 374 inhibits amidase activity with an IC 50 value of 13 nM. AM 374 can be used for the research of neurological disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 86855-26-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-125967.