A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Blueberry extract. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BILBERRY EXTRACT;Vaccinium myrtillus, ext.;Bilberry Seed Oil;Blue Tocal Bilberry Seed Oil;Vaccinium Myrtillus;VACCINIUM MYRTILLUS EXTRACT;BILBERRY EXTRACT 25%;BILBERRYFRUITEXTRACT. CAS No. 84082-34-8. Molecular formula: C27H31O16. Mole weight: 611.53. Purity: 0.95. IUPACName: Bilberry Extract. Product ID: ACM84082348. Alfa Chemistry ISO 9001:2015 Certified.
Blueberry Extract
Blueberry extract is prepared from blueberry, a perennial, ornamental shrub of Ericaceae. Blueberry extract contains nutrients which are essential for protecting eyes from eyestrain or fatigue, and blueberry extract anthocyanin can activate blood circulation around the eyes. Blueberry extract can be used to treat diarrhea, scurvy, and other conditions. Group: Others. Blueberry Extract; Vaccinium Angustifolium L. Cat No: EXTC-004.
Blueberry Fruit Powder
Blueberry Fruit Powder.
CA, FL & NJ
Blueberry Powder
Blueberry juice powder is made from fresh blueberry (vaccinium angustifolium.) with advanced process technology. Blueberry juice powder are rich in anthocyanosides, proanthocyanidins, resveratrol, flavors and tannins inhibit mechanisms of cancer cell development and inflammation. Blueberry powder can be used to eliminate eyestrain, improving eyesight and delaying cerebral nerve to aging. Group: Others. Blueberry Powder; Vaccinium angustifolium. Cat No: EXTC-090.
Blue Dextran
Blue Dextran. Group: Natural polymers and biopolymers. CAS No. 87915-38-6.
Blue dextran (MW 2000000) - from Leuconostoc spp
Blue dextran (MW 2000000) from Leuconostoc spp is an intriguing biomaterial that serves as a vital instrument in the realm of biomedical research. This dye-conjugated polysaccharide, renowned for its extensive molecular dimensions, is ubiquitously employed as a discerning gauge and meticulous exploring agent within the realms of molecular weight ascertainment, gel filtration chromatography, and the profound investigation of vascular permeability. The compound is pharmacologically active and could advance drug research into diseases such as cancer, cardiovascular disease and kidney disease. Synonyms: Blue Dextran 5. CAS No. 87915-38-6. Molecular formula: (C6H10O5)n.
Blue Flag Powder (Unsterilized)
Blue Flag Powder (Unsterilized).
CA, FL & NJ
Blue Glass Helmsley Bottles
Blue Glass Helmsley Bottles. Product ID: PM-011. Product Keywords: Packaging Materials; Glass Packaging; PM-011; Blue Glass Helmsley Bottles. Color: Blue.
Blue Honeysuckle Extract
Blue Honeysuckle Extract. Applications: Can lower blood pressure, improve white blood cell count, but also has the effect of treatment of children with anorexia. Group: Others. Synonyms: Blue Honeysuckle Extract; Lonicera caerulea L.var.enulis Turcz et Herd. Purity: 5%-10%Anthocyanidins, 5%-20% Proanthocyanidins, 4-50:1. Appearance: Yellow brown fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Fruit. Species: Lonicera caerulea L.var.enulis Turcz et Herd. Blue Honeysuckle Extract; Lonicera caerulea L.var.enulis Turcz et Herd; plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-191.
Blue Luminescent Graphene Quantum Dots
Blue Luminescent Graphene Quantum Dots. Group: other nano materials.
Blue Luminescent Hydrophilic Graphene Quantum Dots
Blue Luminescent Hydrophilic Graphene Quantum Dots. Group: other quantum dots.
Blue Luminescent Hydrophobic Graphene Quantum Dots
Blue Luminescent Hydrophobic Graphene Quantum Dots. Group: other quantum dots.
Bluensomycin
Bluensomycin is an amino glycoside antibiotic produced by Streptomyces bluensis var. bluensis. It has anti-gram-positive and negative bacteria activity, and is cross-resistant to streptomycin and neomycin B. Synonyms: Bluensomicina; Bluensin. Grades: >98%. CAS No. 11011-72-6. Molecular formula: C21H39N5O14. Mole weight: 585.56.
Blue Tansy Oil 100% Pure
Blue Tansy Oil 100% Pure. CAS No. . VIGON Item # 510192. Categories: Speciality Ingredients Suppliers.
America & Internationally
Blumeatin
Blumeatin, isolated from Blumea balsamifera DC, could protect liver against injury induced by CCl4 and thioacetamide (TAA) [1]. Uses: Scientific research. Group: Natural products. CAS No. 118024-26-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N2358.
b-L-Xylose-1-phosphate
b-L-Xylose-1-phosphate is an indispensable molecule utilized within the biomedical field, demonstrating to hold promise in the realm of pharmaceutical development, particularly in the realm of researchs targeting the rectification of aberrations pertinent to xylose metabolism.
BLZ945
BLZ945 is an orally active, potent and selective CSF-1R inhibitor, which inhibits CSF-1R activity with an IC50 of 1nM and is more than 1000-fold selective against its closest receptor tyrosine kinase homologs c-KIT and Platelet-derived Growth Factor Receptor beta (PDGFRb). Synonyms: sotuletinib; BLZ 945; BLZ-945. Grades: >98%. CAS No. 953769-46-5. Molecular formula: C20H22N4O3S. Mole weight: 398.48.
BM152054
BM152054, a thiazolidinedione, revealed to be potent PPARg-activators in transient transfection assays in vitro. Synonyms: BM152054; BM 152054; BM-152054; 5-[[4-[2-(5-methyl-2-thiophen-2-yl-1,3-oxazol-4-yl)ethoxy]-1-benzothiophen-7-yl]methyl]-1,3-thiazolidine-2,4-dione; BM 15.2054; BM-15.2054; BM15.2054. CAS No. 213411-84-8. Molecular formula: C22H18N2O4S3. Mole weight: 470.58.
BM-212
BM-212, a piperazine derivative, has been found to be effective in restraining the mycobacteria and exhibit intracellular bactericidal activity at some extent. Uses: Anti-bacterial agents. Synonyms: BM-212; BM 212; BM212. UNII-U9HSU4GZWL; BM212; 1-[[1,5-bis(4-chlorophenyl)-2-methylpyrrol-3-yl]methyl]-4-methylpiperazine; 1-{[1,5-Bis(4-chlorophenyl)-2-methylpyrrol-3-yl]methyl}-4-methylpiperazine; U9HSU4GZWL. Grades: 98%. CAS No. 146204-42-4. Molecular formula: C23H25Cl2N3. Mole weight: 414.37.
BM-2419-1
BM2419-1 is a human topoisomerase I inhibitor produced by Paecilomyces sp. BM2419. It can selectively inhibit human topoisomerase with an IC50 of 0.3 ng/mL. Molecular formula: C18H10O8. Mole weight: 354.27.
BM-2419-2
BM2419-2 is a human topoisomerase I inhibitor produced by Paecilomyces sp. BM2419. It can selectively inhibit human topoisomerase with an IC50 of 0.6 ng/mL. Molecular formula: C19H12O7. Mole weight: 352.29.
BM 567
Thromboxane A2 (TXA2) is a potent thrombogenic and vasoconstrictor eicosanoid. It has been reported as a causal factor in the onset of stroke and myocardial infarction. BM 567 is a dual acting antithrombogenic agent, which is acting as an inhibitor of thromboxane A2 (TXA2) synthase and an antagonist of the TP receptor. It also antagonizes the vascular smooth muscle TP receptor with an IC50 value of 1.1 nM. Synonyms: BM567; BM-567. Grades: ≥98%. CAS No. 284464-77-3. Molecular formula: C18H28N4O5S. Mole weight: 412.5.
BM635
BM635 is a MmpL3 inhibitor with outstanding anti-mycobacterial activity. BM635 has an MIC 50 of 0.12 μM against M. tuberculosis H37Rv. Uses: Scientific research. Group: Signaling pathways. CAS No. 1493762-74-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109587.
BM-962
BM-962 (Compound 31) is a potent small-molecule inhibitor of Bcl-2 with an IC 50 value of 4 nM ( K i =0.8 nM) and Bcl-xL with an IC 50 value of 3.9 nM ( K i <1 nM). BM-962 inhibits the cell growth in H1417 and H146 cell lines with IC 50 values of 9 and 13 nM, respectively. BM-962 is promising for research of cancers [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1391107-57-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-169925.
b-Maleimidopropionic acid hydrazide 99+%
b-Maleimidopropionic acid hydrazide 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
b-Maltosyl azide
b-Maltosyl azide is a useful compound in the biomedical industry commonly used as a reactive probe in click chemistry reactions for the labeling of biomolecules and bioconjugation studies. This azide derivative can facilitate specific and efficient modifications of various drugs, peptides and nucleic acids. Synonyms: 4-O-a-D-Glucopyranosyl-b-D-glucopyranosyl azide. CAS No. 51970-30-0. Molecular formula: C12H21N3O10. Mole weight: 367.3.
b-Mangostin
b-Mangostin. Group: Biochemicals. Grades: Highly Purified. CAS No. 20931-37-7. Pack Sizes: 100mg. Molecular Formula: C25H28O6. US Biological Life Sciences.
Worldwide
Bme18 I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. G↑GWCC CCWG↓G. Activity: 10000u.a./ml. Appearance: 10 X SE-buffer O. Storage: -20°C. Form: Liquid. Source: Bacillus megaterium 18. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 100 μg/ml BSA; 50% glycerol. Cat No: ET-1035RE.
BMeS-p-A
Alfa Chemistry offers BMeS-p-A products for various research purposes. Please contact us by email if you do not find the specification you are looking for on this page. Uses: Functional dyes for photonics and optics. Group: other materials. Alternative Names: 1,4-Diamino-2,5-bis(methylsulfonyl)benzene 2,5-Bis(methylsulfonyl)-1,4-phenylenediamine. CAS No. 1678513-97-7. Pack Sizes: 1G-Glass Bottle with Plastic Insert, 200MG-Glass Bottle with Plastic Insert. Product ID: 2,5-bis(methylsulfonyl)benzene-1,4-diamine. Molecular formula: 264.31. Mole weight: C8H12N2O4S2. CS (=O) (=O)C1=CC (=C (C=C1N)S (=O) (=O)C)N. InChI=1S/C8H12N2O4S2/c1-15(11, 12)7-3-6(10)8(4-5(7)9)16(2, 13)14/h3-4H, 9-10H2, 1-2H3. PBKAXANOUZYEDU-UHFFFAOYSA-N. >95.0%(HPLC).
b-Methylcrotonyl coenzyme A lithium salt, a crucial compound in the biomedicine realm, boasts paramount importance. Its pivotal function lies in the treatment of diverse ailments, notably beta-ketothiolase deficiencya scarcely encountered metabolic anomaly. Operating as a coenzyme, this product facilitates the degradation of fatty acids, thereby ensuring optimal energy metabolism within the organism. Synonyms: (c5:1)Coenzyme a lithium salt; trans-3-Methyl-2-butenoyl Coenzyme A; lithium [ (2R, 3S, 4R, 5R) -5- (6-aminopurin-9-yl) -4-hydroxy-2- [ [hydroxy- [hydroxy- [3-hydroxy-2, 2-dimethyl-4- [ [3- [2- (3-methylbut-2-enoylsulfanyl) ethylamino] -3-oxopropyl] amino] -4-oxobutoxy] phosphoryl] oxyphosphoryl] oxymethyl] oxolan-3-yl] hydrogen phosphate. Grades: ≥ 95%. CAS No. 108347-83-7. Molecular formula: C26H41LiN7O17P3S. Mole weight: 855.57.
b-Methyldigoxin
Cardiotonic. Obtained by the O-methylation of Digoxin. Group: Biochemicals. Alternative Names: (3 β,5 β,12 β)-3-[(O-2,6-Dideoxy-4-O-methyl- β-D-ribo-hexopyranosyl-(14)-O-2,6-dideoxy- β-D-ribo-hexopyranosyl-(14)-2,6-dideoxy- β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxycard-20(22)-enolide; 4-Methyldigoxin; 4-O-Methyldigoxin; Lanirapid; Lanitop; Medigoxin; Methyldigoxin; Metildigoxin. Grades: Highly Purified. CAS No. 30685-43-9. Pack Sizes: 1mg, 2.5mg, 5mg, 10mg. Molecular Formula: C42H66O14. US Biological Life Sciences.
Worldwide
BMF-219
Menin-MLL inhibitor 21 (example 9) is a specific, irreversible inhibitor of Menin-MLL interaction, useful for the study of autoimmune diseases, heteroimmune diseases, cancer, and other diseases dependent on menin-MLL. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Menin-MLL inhibitor 21. CAS No. 2448172-22-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150105.
BMH 21
BMH 21. Group: Biochemicals. Grades: Purified. CAS No. 896705-16-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
BMH-21
BMH-21 is a first-in-class DNA intercalator which inhibits RNA polymerase I ( Pol I ) transcription. BMH-21 possesses anticancer activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 896705-16-1. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-12484.
BMH-21
BMH-21 is a potent small molecule DNA intercalator. BMH-21 binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription. Uses: Enzyme inhibitors. Synonyms: BMH-21; BMH 21; BMH21. Grades: >98%. CAS No. 896705-16-1. Molecular formula: C21H22N4O2. Mole weight: 362.43.
BMI-1026
BMI-1026 is an exceedingly potent and remarkably selective inhibitor utilized in the biomedical sector, specifically zeroes in on the intricate signalling pathway of interleukin-1 receptor-associated kinase 4 (IRAK-4). Synonyms: BMI 1026; BMI1026; 4-(2-Aminopyrimidin-4-yl)-6-(2-aminopyrimidin-4(3H)-ylidene)cyclohexa-2,4-dien-1-one. Grades: >98%. CAS No. 477726-77-5. Molecular formula: C34H60N3O7PS. Mole weight: 280.29.
A cell-permeable indandione compound that inhibits the Bmi1-Ring1A E3 complex ubiquitin ligase activity both in cell-free assays (by 100% against self- and Top2alpha ubiquitination at 25 and 50uM, respectively) and in HeLa cells (by 100% against Bmi1 ubiquitination at 50uM). Shown to greatly potentiate Teniposide (VM26) cancer cytotoxicity (by 10-fold in A375 and A549 cultures at 5.5 and 33uM, respectively) by preventing Top2alpha degradation following VM26 treatment (100% inhibition at 50uM in HeLa cells). Group: Biochemicals. Grades: Highly Purified. CAS No. 31083-55-3. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
BmKb1
BmKb1 is produced by Mesobuthus martensii. BmKb1 has antibacterial activity against Gram-positive bacteria S.aureus, M.luteus, B.subtilis, and Gram-negative bacteria E.coli, and P.aeruginosa. Grades: >97% by HPLC. Molecular formula: C94H147N19O23. Mole weight: 1911.28.
BmKn1
BmKn1 has antibacterial activity. BmKn1 was found in Mesobuthus martensii.
BmKn2
BmKn2 was found in Mesobuthus martensii. BmKn2 has strong antibacterial activity against Gram-positive bacteria S.aureus, M.luteus, B.subtilis, and Gram-negative bacteria E.coli, P.aeruginosa and N.gonorrhoeae. BmKn2 also shows low activity against HIV-1 PV.
BML 111
BML 111 is a FPR2 (lipoxin A4 receptor) agonist. It inhibits tumor-related angiogenesis and reduces tumor growth in hepatoma H22 cell bearing mice. BML 111 also protects against hemorrhagic shock-induced acute lung injury in rats and attenuates renal ischemia/reperfusion injury. Synonyms: BML-111; BML 111; BML111. (5S,6R)-Methyl 5,6,7-trihydroxyheptanoate; methyl (5S,6R)-5,6,7-trihydroxyheptanoate. CAS No. 78606-80-1. Molecular formula: C8H16O5. Mole weight: 192.21.
BML-190
BML-190. Group: Biochemicals. Grades: Purified. CAS No. 2854-32-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
BML-210
BML-210 is a Histone deacetylase (HDAC) inhibitor (IC50 = 87 μM), inducingchanges in gene expression profile. Uses: A histone deacetylase (hdac) inhibitor. Synonyms: BML-210; BML 210; BML210; CAY10433; CAY-10433; CAY 10433N1-(2-aminophenyl)-N8-phenyloctanediamide; N-(2-aminophenyl)-N'-phenyl-octanediamide. Grades: ≥98%. CAS No. 537034-17-6. Molecular formula: C20H25N3O2. Mole weight: 339.43.
BML-210
BML-210, also known as CAY10433, is HDAC inhibitor. BML-210 induces growth inhibition and apoptosis and regulates HDAC and DAPC complex expression levels in cervical cancer cells. BML-210 can inhibit cell growth and induce apoptosis in cervical cancer cells, what correlates with down-regulation of HDAC class I and II and changes in the DAPC expression levels. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BML-210; BML 210; BML210; CAY10433; CAY-10433; CAY 10433. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 537034-17-6. Molecular formula: C20H25N3O2. Mole weight: 339.44. Purity: >98%. IUPACName: N-(2-aminophenyl)-N'-phenyl-octanediamide. Canonical SMILES: O=C(NC1=CC=CC=C1N)CCCCCCC(NC2=CC=CC=C2)=O. Product ID: ACM537034176. Alfa Chemistry ISO 9001:2015 Certified.
A novel non-hydroxamic acid HDAC inhibitor. IC50=5-10uM (HeLa nuclear extract). Induces growth inhibition, proapoptotic and differentiation effects on human leukemia cell lines. Group: Biochemicals. Alternative Names: N1-(2-aminophenyl)-N8-phenyloctanediamide. Grades: Highly Purified. CAS No. 537034-17-6. Pack Sizes: 5mg, 25mg. US Biological Life Sciences.
Worldwide
BML-244
BML-244 is a potent cathespin K inhibitor. Synonyms: BML 244; BML244; (1-formyl-pentyl)-carbamic acid tert-butyl ester; 2-[(tert-Butyloxycarbonyl)amino]hexanal. Grades: 98%. CAS No. 104062-70-6. Molecular formula: C11H21NO3. Mole weight: 215.29.
BML-258 HCl
Cas No. 1072443-89-0.
Bml-259
BML-259 is a potent cyclin-dependent kinase 5 (Cdk5) inhibitor, with IC50s of 64 and 98 nM for Cdk5 and Cdk2, respectively. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: White to off-white solid. CAS No. 267654-00-2. Molecular formula: C14H16N2OS. Mole weight: 260.4. Purity: >98%. IUPACName: 2-phenyl-N-(5-propan-2-yl-1,3-thiazol-2-yl)acetamide. Canonical SMILES: O=C(NC1=NC=C(C(C)C)S1)CC2=CC=CC=C2. Product ID: ACM267654002. Alfa Chemistry ISO 9001:2015 Certified.
BML-275
Cas No. 866405-64-3.
BML-277
BML-277 is a selective APT-competitive inhibitor of the DNA damage response signaling enzyme CHK2 ( IC50 =15 nM). Uses: A selective apt-competitive inhibitor. Synonyms: BML-277; BML 277; BML277; Chk2 Inhibitor II;2-[4-(4-chlorophenoxy)phenyl]-3H-benzimidazole-5-carboxamide. Grades: ≥98%. CAS No. 516480-79-8. Molecular formula: C20H14ClN3O2. Mole weight: 363.80.
BML-278
BML-278 is a selective Sirt1 activator (EC150 = 1μM) structurally based on a dihydropyridine scaffold. It has much weaker effects on Sirt2 and Sirt3. BML-278 is active in whole cells and arrests cell cycle at G1/S phase in U937 cells. It has much weaker effects on Sirt2 and Sirt3. BML-278 is active in whole cells and arrests cell cycle at G1/S phase in U937 cells. Synonyms: BML 278; BML278. Grades: ≥95%. CAS No. 120533-76-8. Molecular formula: C24H25NO4. Mole weight: 391.5.
BML-278
BML-278 is a SIRT1 activator ( EC 150 : 1 μM). BML-278 increases H3K9 methylation and inhibits H3K9 acetylation in both the paternal and maternal pronucleus. BML-278 improves early embryonic development. BML-278 arrests the cell cycle at the G1/S phase, and reduces senescence in primary human mesenchymal cells. BML-278 reduces tubulin acetylation in U937 cells. BML-278 also increases mitochondrial density in murine C2C12 myoblasts [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 120533-76-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W025074.
A structurally novel activator of SIRT1 (EC150=1uM). Displays selectivity over SIRT2 and 3 (EC150=25 and 50uM respectively). Cell permeable. Group: Biochemicals. Alternative Names: N-Benzyl-3,5-dicarbethoxy-4-phenyl-1,4-dihydropyridine. Grades: Highly Purified. Pack Sizes: 5mg, 25mg. US Biological Life Sciences.
Worldwide
BML-284
BML-284 is potent, selective and cell-permeable Wnt signaling activator. It induces β-catenin and transcription factor (TCF)-dependent transcriptional activity in 293T cells in a dose dependent manner with an EC50 of 0.7 mM in vitro. Uses: Bml-284 may be a useful tool in the study of physiological processes that involve the wnt pathway. Synonyms: BML 284; 2-Amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine; 4-N-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)pyrimidine-2,4-diamine. Grades: >98%. CAS No. 853220-52-7. Molecular formula: C19H18N4O3. Mole weight: 350.37.
BML-286
A small molecule inhibitor of the PDZ domain of Dishevelled (Dvl): an essential protein in the Wnt signaling pathways. This compound reduced the levels of apoptosis in the hyaloid vessels of the eye and also suppressed the growth of prostate cancer PC-3 cells. It is a useful tool for studies dissecting the Wnt signaling pathways. Group: Biochemicals. Alternative Names: 2- [ [3- [ (2-phenylacetyl) amino] benzoyl] amino] benzoic Acid; 2- [ [3- [ (phenylacetyl) amino] benzoyl] amino] benzoic Acid. Grades: Highly Purified. CAS No. 294891-81-9. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
BML-287
BML-287 is a selective inhibitor of secreted frizzled related protein-1 (sFRP-1). BML-287 is a useful tool for studying the Wnt signaling pathway. Group: Biochemicals. Alternative Names: N-[2- (3, 4-Dimethoxyphenyl) ethyl]-2-ethyl-5- (phenylsulfonyl) benzenesulfonamide. Grades: Highly Purified. CAS No. 915754-05-1. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
BML-288
BML-288. Group: Biochemicals. Alternative Names: 6,7-Dihydro-5-methyl-6-oxo-N-1,3,4-thiadiazol-2-yl-5H-furo[2,3-f]indole-7-carboxamide. Grades: Highly Purified. CAS No. 851681-89-5. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C14H10N4O3S. US Biological Life Sciences.
Worldwide
BMMCC
BMMCC. Pack Sizes: Milligram Quantities: 50 mg. Order Number: B111.
www.prochemonline.com
BMN-673 8R,9S
BMN-673 is an orally bioavailable inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) with potential antineoplastic activity. PARP inhibitor BMN-673 selectively binds to PARP and prevents PARP-mediated DNA repair of single strand DNA breaks via the base-excision repair pathway. This enhances the accumulation of DNA strand breaks, promotes genomic instability and eventually leads to apoptosis. PARP catalyzes post-translational ADP-ribosylation of nuclear proteins that signal and recruit other proteins to repair damaged DNA and is activated by single-strand DNA breaks. BMN-673 has been proven to be highly active in mouse models of human cancer and also appears to be more selectively cytotoxic with a longer half-life and better bioavailability as compared to other compounds in development. Synonyms: Talazoparib (8R,9S); (8R,9S)-BMN-673; BMN673 (8R,9S); BMN 673 (8R,9S). Grades: >98%. CAS No. 1207456-00-5. Molecular formula: C19H14F2N6O. Mole weight: 380.35.
BMP-22
BMP-22 is an inhibitor of autotaxin with IC50 of 170 nM. It is selective for autotaxin over the phosphodiesterases NPP6 and NPP7 at 10 μM. BMP-22 inhibits autotaxin-mediated production of lysophosphatidic acid (LPA) from lysophosphatidylcholine (LPC) in vitro in a concentration-dependent manner. MP-22 can decrease the number of lung metastatic foci in a B16/F10 syngeneic mouse melanoma model of lung metastasis. Synonyms: 4-pentadecylbenzylphosphonic acid; BMP22; BMP 22. Grades: ≥95%. CAS No. 1306684-90-1. Molecular formula: C22H39O3P. Mole weight: 382.52.
BMP Inhibitor II, DMH1 (ALK2/3 Inhibitor, DMH1, Bone Morphogenetic Protein Inhibitor, DMH1, 4- (6- (4-Isopropoxyphenyl) pyrazolo[1, 5-a]pyrimidin-3-yl) quinoline)
A cell-permeable pyrrazolopyrimidine compound that inhibits against R/VEGFR2, ALK2/BMPR-I, AMPK kinase activity (IC50=25.1, 148, and 234.6nM, respectively), while exhibiting much reduced or little effect toward ALK5/TGFbR-I, ZAPK, Syk, PKCth, PKA, or JAK3. Shown to block both BMP pathway-dependent dorsoventral development (EC100=2.5uM) and VEGF signaling-dependent intersomitic vessel formation (EC50=5uM) in zebrafish embryo in vivo. Commonly used in combination with AMPK activators AICAR and/or Metformin for studying AMPK-dependent cellular events in vitro and physiological responses in animals in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 1206711-16-1. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
BMP Inhibitor III, LDN-212854 (Abl Inhibitor V, LDN212854, Bone Morphogenetic Protein Inhibitor III, PDGFR Tyrosine Kinase Inhibitor XXIV, RIP2 Inhibitor I, RIPK2 Inhibitor I, 5-(6-(4-(Piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline)
A cell-permeable pyrazolopyrimidinyl quinoline that is superior to Dorsomorphin and DMH1 as an ATP-site-targeting, ALK1/2 inhibitor (IC50 = 2.40 and 1.30nM, respectively; [ATP] = 6uM) with respect to both potency and selectivity over ALK3/4/5 (IC50 = 0.858, 2.133, and 9.276uM, respectively). Also a potent RIPK2 inhibitor (IC50 = 6nM) with reduced potency against ABL1/c-abl, PDGFR-beta, ALK3, and PDGFR-alpha (IC50 = 40, 68, 85.8, and 650nM, respectively) and little inhibitory activity toward a panel of more than 190 kinases. Effectively inhibits ALK2- and ALK3-mediated C2C12 osteogenic differentiation (IC50 = 10 and 40.5nM, respectively) in vitro and prevents constitutively active ALK2 Q207D mutant-induced heterotopic ossification in mice (6mg/kg/12h via i.p.) in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C??H??N?. US Biological Life Sciences.
Worldwide
BMPO
BMPO (BocMPO) is a cell-permeable superior spin trap with favorable chemical and spectroscopic features. BMPO (BocMPO) can be used for detecting thiyl radicals, hydroxyl radicals, superoxide anions and glutathiyl radicals [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BocMPO. CAS No. 387334-31-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121137.
BMPS
Cas No. 55750-62-4.
BMPS
BMPS is a nonclaevable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Uses: Scientific research. Group: Signaling pathways. CAS No. 55750-62-4. Pack Sizes: 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-42146.
BmPyPhB
BmPyPhB. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,3-Bis[3,5-di(pyridin-3-yl)phenyl]benzene. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1030380-38-1. Molecular formula: C38H26N4. Mole weight: 538.64 g/mol. Product ID: ACM1030380381. Alfa Chemistry ISO 9001:2015 Certified.
BMS-002
BMS-002 is a selective antogonist of lysophosphatidic acid (LPA) receptor-1 developed to treat diabetic nephropathy. In eNOS-/- db/db mouse model, BMS-002 significantly decreased the level of proteinuria. Uses: The potential treatment of diabetic nephropathy. Synonyms: BMS 002; BMS002.
BMS-180048
BMS-180048, also know as Avitriptan Fumarate, has been found to be a5HT-1B/1D-receptor agonist that was once studied as an anti-migraine agent. Synonyms: Avitriptan Fumarate; BMS 180048; BMS-180048; BMS180048; UNII-2G25KE3954; 3-(3-(4--(5-methoxy-4-pyrimidinyl)-1-piperazinyl)propyl)-N-methyl-1H-indole-5-methanesulfonamide fumarate. Grades: 98%. CAS No. 171171-42-9. Molecular formula: C26H34N6O7S. Mole weight: 574.65.
BMS 180448
BMS 180448 is a prototype mitochondrial ATP-sensitive K+ channel stimulant. The cardioprotective effects of BMS-180448 against I/R heart injury may result from direct activation of mitoK(ATP) channel in cardiomyocytes. In Sep 2003, Phase-II for Myocardial ischaemia in USA was discontinued. Uses: Myocardial ischaemia. Synonyms: BMS 180448; BMS-180448; BMS180448; trans-N-(4-chlorophenyl)-N'-cyano-N''-(6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl)- Guanidine. Grades: 98%. CAS No. 144264-47-1. Molecular formula: C20H18ClN5O2. Mole weight: 395.85.