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| Product | Description | |
|---|---|---|
| BMS 299897 | BMS 299897 is a known γ-secretase inhibitor that effectively reduces amyloid β-peptide (A β) in transgenic mice and guinea pigs. Studies have shown the possibility of using BMS 299897 in the treatments for Alzheimers patients. Group: Biochemicals. Alternative Names: 2-[ (1R) -1-[[ (4-Chlorophenyl) sulfonyl] (2, 5-difluorophenyl) amino]ethyl]-5-fluorobenzenebutanoic Acid. Grades: Highly Purified. CAS No. 290315-45-6. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| BMS 299897 | BMS 299897, under the IUPAC name 4-[2-[(1R)-1-(N-(4-chlorophenyl)sulfonyl-2,5-difluoroanilino)ethyl]-5-fluorophenyl]butanoic acid, synthesized by the radiosynthesis group at Bristol-Myers Squibb, is a β-secretase inhibitor that has the potential for treatment of Alzheimer's diseases (IC50 = 12 nM; gamma-secretase express: EC50 = 7 nM (CHO cells)). BMS 299897 blocks the formation of Aβ40 (IC50 = 7.9 nM) and Aβ42 (IC50 = 7.9 nM) in the brain, and reduces Aβ in the brain, plasma and cerebrospinal fluid in vivo. Synonyms: 4-[2-[(1R)-1-(N-(4-chlorophenyl)sulfonyl-2,5-difluoroanilino)ethyl]-5-fluorophenyl]butanoic acid; 4-(2-((1R)-1-(((4-chlorophenyl)sulfonyl)-2,5-difluoroanilino)ethyl)-5-fluorophenyl)butanoic acid; BMS299897; BMS 299897; BMS-299897; 290315-45-6; 2-[(1R)-1-[[(4-Chlorophenyl)sulfonyl](2,5-difluorophenyl)amino]ethyl]-5-fluoro-benzenebutanoic acid; C24H21ClF3NO4S; CHEMBL247471; SCHEMBL6394108; DTXSID50460039; 3496AH; ZINC28883606; AKOS024457319; CCG-222540; CS-1339; NCGC00346875-01; HY-50883; KB-75603; DB-017854; W-5550; BRD-K02950022-001-01-1; 2-[(1R)-1-[[(4-chlorophenyl)sulfonyl](2,5-difluorophenyl)amino]ethyl]-5-fluoroBenzenebutanoic acid; BMS 299897|2-[(1R)-1-[[(4-Chlorophenyl)sulfonyl](2,5-difluorophenyl)amino]ethyl-5-fluorobenzenebutanoic acid. CAS No. 290315-45-6. Molecular formula: C24H21ClF3NO4S. Mole weight: 511.94. |  |
| BMS-299897 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| BMS 299897, gamma-Secretase Inhibitor XXIV (4-(2-((1R)-1-(((4-Chlorophenyl)sulfonyl)-2,5-difluoroanilino)ethyl)-5-fluorophenyl)butanoic Acid, BMS-299897, BMS 299897) | An orally bioavailable sulfonamide compound that acts as a potent, reversible and allosteric y-secretase activity inhibitor with ~15-fold greater selectivity over Notch-1 proteolysis processing (IC50=7.1 and 105.9nM in HEK293-wtAPP) and preferentially inhibits PS1 (presenillin 1)-comprised y-secretase (EC50=8, 108, 286 and 29nM for PS1, Triple PS1-L172M,T281P, L282I, PS2 and Triple PS2-M178L, P287T, I288L), respectively). Shown to reduce the levels of Ab38, Ab40 and Ab42 in Tg2576 mice, Ab40 brain and plasma in APP-YAC mice (ED50=30 and 16mg/kg, p.o.) and Abtotal brain, CSF and plasma in guinea pigs (ED50=30mg/kg, i.p.). Group: Biochemicals. Grades: Highly Purified. CAS No. 290315-45-6. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| BMS-3 | BMS-3, a LIMK1 inhibitor, could be probably influence the migration and cycle progression of cells so that has patential value in studying its effect against cancer. Synonyms: N-(5-(1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl)thiazol-2-yl)cyclopropanecarboxamide; BMS3; BMS 3; Cyclopropanecarboxamide, N-[5-[1-(2,6-dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl]-2-thiazolyl]-; N-{5-[1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl]-1,3-thiazol-2-yl}cyclopropanecarboxamide. Grade: 95%. CAS No. 1338247-30-5. Molecular formula: C17H12Cl2F2N4OS. Mole weight: 429.27. | |
| BMS-3 | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BMS303141 | BMS303141 is a potent inhibitor of ATP citrate lyase (ACL). BMS-303141 inhibits lipid synthesis in HepG2 cells with an IC50 of 8 μM, and lowers plasma triglycerides in a murine hyperlipdemia model. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BMS303141; BMS-303141; BMS 303141. Product Category: Inhibitors. Appearance: White to off-white solid powder. CAS No. 943962-47-8. Molecular formula: C19H15Cl2NO4S. Mole weight: 424.3. Purity: >98%. IUPACName: 3,5-dichloro-2-hydroxy-N-(4-methoxy-[1,1'-biphenyl]-3-yl)benzenesulfonamide. Canonical SMILES: O=S(C1=CC(Cl)=CC(Cl)=C1O)(NC2=CC(C3=CC=CC=C3)=CC=C2OC)=O. Product ID: ACM943962478-1. Alfa Chemistry ISO 9001:2015 Certified. |  |
| BMS303141 | BMS 303141 is a cell-permeable, 2-hydroxy-N-arylbenzenesulfonamide that inhibits ACL with an IC50 value of 0.13 μM. BMS 303141 has been reported to reduce weight gain and lower plasma cholesterol, triglycerides, and glucose in a mouse model of hyperlipidemia. Synonyms: BMS303141; BMS-303141; BMS 303141. CAS No. 943962-47-8. Molecular formula: C19H15Cl2NO4S. Mole weight: 424.30. | |
| BMS 303141 | BMS 303141. Group: Biochemicals. Grades: Purified. CAS No. 943962-47-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BMS-303141 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BMS-303141 | BMS-303141 is a potent, cell-permeable ATP-citrate lyase (ACL) inhibitor with an IC50 of 0.13 ?M. Uses: Scientific research. Group: Signaling pathways. CAS No. 943962-47-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-16107. |  |
| BMS 303141 (ATP Citrate Lyase Inhibitor, Orally Bioavailable, 3,5-Dichloro-2-hydroxy-N-(4-methoxy[1,1'-biphenyl]-3-yl)-benzenesulfonamide) | ATP citrate lyase (ACL) inhibitor (IC50 = 0.13um for human recombinant ACL); blocks lipid synthesis (IC50 = 8um in HepG2 cells). Displays no cytotoxicity up to a concentration of 50um. Lowers plasma glucose and triglycerides in a mouse model of hyperlipidemia. Orally bioavailable. Group: Biochemicals. Grades: Highly Purified. CAS No. 943962-47-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| BMS 309403 | BMS 309403. Group: Biochemicals. Grades: Purified. CAS No. 300657-03-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BMS 309403 | BMS 309403 is a potent, selective and cell-permeable inhibitor of adipocyte fatty acid binding protein (FABP4) with a Ki of less than 2 nM, which exhibits Ki values of 250 nM for FABP3 and 350 nM for FABP5. BMS 309403 interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS 309403 is a biphenyl azole inhibitor against fatty acid binding protein 4 (FABP4) and regarded as a lead compound for effective treatment of obesity related cardio-metabolic diseases. Synonyms: BMS-309403; BMS309403; Adipocyte FABP Inhibitor; A-FABP Inhibitor; ALBP Inhibitor; aP2 Inhibitor; FABP4 Inhibitor; Fatty Acid Binding Protein 4 Inhibitor. Grade: ≥98%. CAS No. 300657-03-8. Molecular formula: C31H26N2O3. Mole weight: 474.55. | |
| BMS-309403 | BMS-309403 is a potent, orally active and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor with Kis of <2, 250, and 350 nM for FABP4, FABP3, and FABP5, respectively. BMS-309403 interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS-309403 improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 300657-03-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-101903. | |
| BMS-309403 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BMS-317180 | BMS-317180 is a potent, and orally effective growth hormone secretagogue (GHS) that shows an excellent safety profile in preclinical studies. Synonyms: BMS317180; BMS 317180; (S)-2-(5-(1-(2-amino-2-methylpropanamido)-2-(benzyloxy)ethyl)-1H-tetrazol-1-yl)ethyl (4-hydroxybutyl)carbamate. Grade: >98%. CAS No. 295337-71-2. Molecular formula: C26H30N5O2P. Mole weight: 463.54. | |
| BMS-337197 | BMS-337197 is a a potent inhibitor of IMPDH with potential anticancer activity. Synonyms: BMS 337197; BMS337197; N-(2-(2-((3-methoxy-4-(oxazol-5-yl)phenyl)amino)oxazol-5-yl)phenyl)-N-methyl-2-morpholinoacetamide. Grade: >98%. CAS No. 267645-83-0. Molecular formula: C24H34N5OP. Mole weight: 489.53. | |
| BMS-341400 methanesulfonate | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BMS-344577 | BMS-344577 is aroylguanidine-based lactam derivative, which is a potent FXa inhibitor (FXa IC(50)=4 nM, EC(2xPT)=7 microM). Uses: Aroylguanidine-based factor xa inhibitor. Synonyms: BMS-344577; BMS344577; BMS 344577; UNII-U259PQB19A; CHEMBL570867; U259PQB19A; BDBM35316; BDBM50328724; N5-[[[(3S)-Hexahydro-2-oxo-1-[2-oxo-2-(1-pyrrolidinyl)ethyl]-1H-azepin-3-yl]imino][(2-methyl-5-benzofuranyl)amino]methyl]-N2,N2-dimethyl-2,5-pyridinedicarboxamide; (S,E)-N2,N2-dimethyl-N5-(N'-(2-methylbenzofuran-5-yl)-N-(2-oxo-1-(2-oxo-2-(pyrrolidin-1-yl)ethyl)azepan-3-yl)carbamimidoyl)pyridine-2,5-dicarboxamide. Grade: ≥95%. CAS No. 288079-93-6. Molecular formula: C31H37N7O5. Mole weight: 587.67. | |
| BMS 345541 | BMS 345541. Group: Biochemicals. Grades: Purified. CAS No. 547757-23-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BMS-345541 | BMS-345541 is a highly selective inhibitor of the catalytic subunits of IKK-2 and IKK-1 with IC50 of 0.3 μM and 4 μM, respectively. Synonyms: BMS-345541 free base; BMS345541; UNII-26SU0NEF5F; BMS 345541; BMS-345541. Grade: >98%. CAS No. 445430-58-0. Molecular formula: C14H17N5. Mole weight: 255.32. | |
| BMS-345541 | BMS-345541 is a selective inhibitor of the catalytic subunits of IKK ( IKK-2 IC 50 =0.3 μM, IKK-1 IC 50 =4 μM). BMS-345541 binds at an allosteric site of IKK. Uses: Scientific research. Group: Signaling pathways. CAS No. 445430-58-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10519. | |
| BMS-345541 | ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. | |
| BMS-345541 hydrochloride | BMS-345541 hydrochloride is a selective inhibitor of the catalytic subunits of IKK ( IKK-2 IC 50 =0.3 μM, IKK-1 IC 50 =4 μM). BMS-345541 binds at an allosteric site of IKK. Uses: Scientific research. Group: Signaling pathways. CAS No. 547757-23-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10518. | |
| BMS 345541 trifluoroacetate salt | BMS 345541 is a cell-permeable inhibitor of the IκB kinases IKKα with IC50s of 4 uM and IKKβ with IC50s of 0.3 μM, which binds at allosteric site of the enzyme and displays ~10-fold greater selectivity at IKK-2 over IKK-1. It exhibits no effect against a panel of 15 other kinases. BMS 345541 is used to explore novel roles for IKK phosphorylation and NF-κB signaling. Synonyms: IKK Inhibitor III. Grade: ≥98%. CAS No. 547757-23-3. Molecular formula: C14H17N5·2CF3COOH. Mole weight: 483.4. | |
| BMS-347070 | BMS-347070 is a COX-2 inhibitor, initially developed for the treatment for Colorectal cancer. Synonyms: (3Z)-3-[(4-bromophenyl)-(4-methylsulfonylphenyl)methylidene]oxolan-2-one; BMS-347070; BMS 347070; BMS347070; UNII-0CKM4H090C; 0CKM4H090C; SCHEMBL6882900; SCHEMBL6882905. Grade: >98%. CAS No. 197438-73-6. Molecular formula: C18H15BrO4S. Mole weight: 407.28. | |
| BMS-351 | BMS-351 is a selective and nonsteroidal CYP17A1 lyase inhibitor with good selectivity over steroidogenic CYPs 21A2 and 11B1. BMS-351 has become a preclinical candidate to treat Castration-resistant prostate cancer (CRPC) and is likely to minimize the side effects of current therapies because of its exceptional selectivity. Uses: Castration-resistant prostate cancer. Synonyms: BMS-351; BMS 351; BMS351; 4-(4-methylpyridin-3-yl)-1-(2,2,2-trifluoroethyl)-1H-benzo[d]imidazole. Grade: 98%. CAS No. 1370001-71-0. Molecular formula: C15H12F3N3. Mole weight: 291.28. | |
| BMS-354326 | BMS-354326 is a tryptase inhibitor with IC50 value of 1.8 nM. It has excellent selectivity against trypsin and most other related serine proteases. Synonyms: BMS-354326; BMS 354326; BMS354326; CHEMBL306448; BDBM50144532.(2S,3R)-4-oxo-1-((4-(1-oxo-6-phenylhexyl)-1-piperazinyl)carbonyl)-3-(2-(3-piperidinyl)ethyl)- 2-Azetidinecarboxylic acid. Grade: 98%. CAS No. 708258-16-6. Molecular formula: C28H40N4O5. Mole weight: 512.65. | |
| BMS358233 | BMS358233 is a potent Lck inhibitor. It has excellent cellular activities against T-cell proliferation. Uses: Bms358233 has excellent cellular activities against t-cell proliferation. Synonyms: BMS-358233; BMS 358233; 6-Benzothiazolecarboxamide, N-(2-chloro-6-methylphenyl)-2-((6-methyl-2-((((2R)-tetrahydro-2-furanyl)methyl)amino)-4-pyrimidinyl)amino)-. Grade: 98%. CAS No. 601519-75-9. Molecular formula: C25H25ClN6O2S. Mole weight: 509.02. | |
| BMS-36313 | BMS-363131 is very potent inhibitor of human tryptase with inhibitory activity against bovine trypsin. Uses: Tryptase inhibitor. Synonyms: BMS-363131; BMS 363131; BMS363131. (2S,3R)-3-[[(3R)-1-carbamimidoylpiperidin-3-yl]methyl]-4-oxo-1-[4-(6-phenylhexanoyl)piperazine-1-carbonyl]azetidine-2-carboxylic acid. Grade: ≥98%. CAS No. 384829-65-6. Molecular formula: C28H40N6O5. Mole weight: 540.66. | |
| BMS-378806 | BMS-378806 selectively inhibits the binding of HIV-1 gp120 to the CD4 receptor with EC50 of 0.85-26.5 nM in virus. Synonyms: BMS-378806; BMS 378806; BMS378806; BMS-806; BMS806; Bms 806. Grade: >98%. CAS No. 357263-13-9. Molecular formula: C22H22N4O4. Mole weight: 406.43. | |
| BMS-394136 | BMS-394136 is a synthetic bio-active chemical. Uses: A synthetic bio-active chemical. Synonyms: BMS-394136; BMS 394136; BMS394136; UNII-M694U7167K. [(7R)-7-(3,4-dichlorophenyl)-5-methyl-1,7-dihydropyrazolo[1,5-a]pyrimidin-6-yl]-[(2S)-2-(4-fluorophenyl)pyrrolidin-1-yl]methanone. Grade: ≥98%. CAS No. 343246-73-1. Molecular formula: C24H21Cl2FN4O. Mole weight: 471.35. | |
| BMS-419437 | BMS-419437 is a synthetic organic bio-active chemical. Uses: A synthetic organic bio-active chemical. Synonyms: BMS-419437; BMS419437; BMS 419437; UNII-09RR39UU4V; CHEBI:34550; AC1NQZWA; BMS-387032 analog 2. N-[5-[(5-tert-butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]-2-[4-[(1,3-dihydroxypropan-2-ylamino)methyl]phenyl]acetamide. Grade: ≥98%. CAS No. 333389-24-5. Molecular formula: C23H30N4O4S2. Mole weight: 490.64. | |
| BMS 433771 | BMS 433771 is a potent inhibitor of RSV replication in vitro with an average EC of 20nM. Uses: Viral fusion protein inhibitor. Synonyms: BMS 433771; BMS433771; BMS-433771; BMS-433771 HCl hydrate; BMS-433771 HCl; BMS-433771 hydrochloride. 1-cyclopropyl-1,3-dihydro-3-((1-(3-hydroxypropyl)-1H-benzimidazol-2-yl)methyl)-2H-Imidazo(4,5-c)pyridin-2-one. Grade: ≥98%. CAS No. 380603-10-1. Molecular formula: C20H21N5O2. Mole weight: 363.41. | |
| BMS-433771 bis-hydrochloride monohydrate | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BMS-433796 | BMS-433796 is a γ-secretase inhibitor. Chronic dosing of BMS-433796 in Tg2576 mice suggested a narrow therapeutic window and Notch-mediated toxicity at higher doses. Uses: Gamma secretase inhibitors and modulators. Synonyms: BMS433796; BMS-433796; BMS 433796. (2S)-2-[[(2S)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]amino]-N-[(5S)-3-methyl-4-oxo-5H-2,3-benzodiazepin-5-yl]propanamide; BMS-433796; UNII-R1E8M783K2; 935525-13-6; CHEMBL247361; R1E8M783K2; ZINC28899741; (alphaS)-N-[(1S)-2-[[(5S)-4,5-Dihydro-3-methyl-4-oxo-3H-2,3-benzodiazepin-5-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluoro-alpha-hydroxybenzeneacetamide; (S)-2-((S)-2-(3,5-difluorophenyl)-2-hydroxyacetamido)-N-((S)-3-methyl-4-oxo-4,5-dihydro-3H-benzo[d][1,2]diazepin-5-yl)propanamide; Benzeneacetamide, N-((1S)-2-(((5S)-4,5-dihydro-3-methyl-4-oxo-3H-2,3-benzodiazepin-5-yl)amino)-1-methyl-2-oxoethyl)-3,5-difluoro-alpha-hydroxy-, (alphaS)-. CAS No. 935525-13-6. Molecular formula: C21H20F2N4O4. Mole weight: 430.15. | |
| BMS453 | BMS453 (BMS-189453), a synthetic retinoid, is a RAR? agonist and a RAR?/RAR? antagonist. BMS453 inhibits breast cell growth predominantly through the induction of active TGF?[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-189453. CAS No. 166977-43-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100608. | |
| BMS 453 | BMS 453 is a synthetic retinoid that acts as an RARβ agonist in vivo, and also an RARα and RARγ antagonist in vitro. It inhibits the proliferation of breast cells by inducing active transforming growth factor β (TGFβ) and causes G1 arrest. Synonyms: BMS453; BMS 453; BMS-453; BMS 189453; BMS-189453; BMS189453. 4-[(1E)-2-(5,6-Dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-benzoic acid. Grade: ≥98% by HPLC. CAS No. 166977-43-1. Molecular formula: C27H24O2. Mole weight: 380.48. | |
| BMS 453 | BMS 453. Group: Biochemicals. Grades: Purified. CAS No. 166977-43-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| BMS 470539 dihydrochloride | BMS 470539 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 457893-92-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BMS 470539 dihydrochloride | BMS 470539 dihydrochloride is a potent and selective melanocortin MC1 receptor agonist (IC50 = 120 nM) with anti-inflammatory activity. It also inhibits leukocyte trafficking. Synonyms: BMS 470539 dihydrochloride; BMS470539 dihydrochloride; BMS-470539 dihydrochloride; 1-[1-(3-Methyl-L-histidyl-O-methyl-D-tyrosyl)-4-phenyl-4-piperidinyl]-1-butanone dihydrochloride. Grade: ≥98% by HPLC. Molecular formula: C32H41N5O4.2HCl. Mole weight: 632.62. | |
| BMS-470539 dihydrochloride | BMS 470539 dihydrochloride is a highly potent and selective melanocortin-1 receptor (MC1) agonist with an IC50 of 120 nM, an EC50 of 28 nM. It exhibits anti-inflammatory properties. Synonyms: 1-[1-(3-Methyl-L-histidyl-O-methyl-D-tyrosyl)-4-phenyl-4-piperidinyl]-1-butanone dihydrochloride; BMS 470539 dihydrochloride. CAS No. 2341796-82-3. Molecular formula: C32H43Cl2N5O4. Mole weight: 632.63. | |
| BMS480404 | BMS480404 is a potent small molecule inhibitor. It bounds to human keratinocyte fatty acid-binding protein. Synonyms: BMS-480404; BMS 480404; (S)-2-(2,3-bis(2-chlorobenzyloxy)phenyl)-2-hydroxyacetic acid. Grade: 98%. CAS No. 533889-36-0. Molecular formula: C22H18Cl2O5. Mole weight: 433.28. | |
| BMS 488043 | BMS-488043 is a small-molecule HIV fusion inhibitor. Uses: Hiv fusion inhibitor. Synonyms: BMS-488043; 452296-83-2; BMS 043; BMS 488043; 1-(4-benzoylpiperazin-1-yl)-2-(4,7-dimethoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione; BMS043; BMS-043; CHEMBL238103; MKS21EJ435; 1,2-Ethanedione, 1-(4-benzoyl-1-piperazinyl)-2-(4,7-dimethoxy-1H-pyrrolo(2,3-c)pyridin-3-yl)-; 1-Benzoyl-4-(2-(4,7-dimethoxy-1H-pyrrolo(2,3-c)pyridin-3-yl)-2-oxoacetyl]piperazine; 1-(4-Benzoylpiperazin-1-yl)-2-(4,7-dimethoxy-1H-pyrrolo(2,3-c)pyridin-3-yl)ethane-1,2-dione; UNII-MKS21EJ435; DBPMWRYLTBNCCE-UHFFFAOYSA-N; 1-BENZOYL-4-(2-(4,7-DIMETHOXY-1H-PYRROLO(2,3-C)PYRIDIN-3-YL)-2-OXOACETYL)PIPERAZINE; BMS488043; SCHEMBL2688411; DTXSID501006367; GLXC-15766; BDBM50228465; AKOS040750864; DB05532; HY-14135; TS-08685; CS-0003220; NS00071850; Q27284087; n-(benzoyl)-n'-[(4,7-dimethoxy-6-azaindol-3-yl)-oxoacetyl]-piperazine; n-(benzoyl)-n'-[(4,7-dimethoxy-6-azaindol-3-yl)-oxoacetyl]piperazine; 1-(4-benzoyl-1-piperazinyl)-2-(4,7-dimethoxy-1H-pyrrolo(2,3-c)pyridin-3-yl)-1,2-ethanedione; 1-[4-(benzoyl)piperazin-1-yl]-2-(4,7-dimethoxy-1h-pyrrolo[5,4-c]pyridin-3-yl)ethane-1,2-dione; 857500-24-4; Piperazine, 1-benzoyl-4-[2-(4,7-dimethoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)-1,2-dioxoethyl]-. Grade: ≥98%. CAS No. 452296-83-2. Molecular formula: C22H15NO7. Mole weight: 405.4. | |
| BMS493 | BMS493 is an inverse pan-retinoic acid receptor (RAR) agonist. BMS493 increases nuclear corepressor interaction with RARs. BMS493 also could prevent retinoic acid-induced differentiation[1][2]. BMS493 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 215030-90-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108529. | |
| BMS 493 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BMS 493 | BMS 493 is a pan-retinoic acid receptor (pan-RAR) inverse agonist. Synonyms: 4-[(1E)-2-[5,6-Dihydro-5,5-dimethyl-8-(phenylethynyl)-2-naphthalenyl]ethenyl]-benzoic Acid; BMS-493; BMS493; (E)-4-[2-[5,6-Dihydro-5,5-dimethyl-8-(2-phenylethynyl)naphthalen-2-yl]ethen-1-yl]benzoic acid; Benzoic acid, 4-[(1E)-2-[5,6-dihydro-5,5-dimethyl-8-(2-phenylethynyl)-2-naphthalenyl]ethenyl]-. Grade: 97%. CAS No. 215030-90-3. Molecular formula: C29H24O2. Mole weight: 404.50. | |
| BMS 493 | BMS 493. Group: Biochemicals. Grades: Purified. CAS No. 215030-90-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BMS-5 | BMS-5, a LIMK inhibitor, has been found to restrain the cofilin phosphorylation in MDA-MB-231 breast cancer cells. Synonyms: LIMKi 3; N-(5-(1-(2,6-dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl)thiazol-2-yl)isobutyramide; N-{5-[1-(2,6-dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl]-1,3-thiazol-2-yl}-2-methylpropanamide; BMS 5; BMS5. Grade: 98%. CAS No. 1338247-35-0. Molecular formula: C17H14Cl2F2N4OS. Mole weight: 431.29. | |
| BMS-5 | BMS-5 (LIMKi 3) is a potent LIMK inhibitor with IC50s of 7 nM and 8 nM for LIMK1 and LIMK2, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LIMKi 3. CAS No. 1338247-35-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18305. | |
| BMS-502 | BMS-502 is an inhibitor of diacylglycerol kinase α (DGK-α), DGK-ζ, and DGK-Ι with IC50s of 0.0046, 0.0021, and 0.0026 μM, respectively. BMS-502 induces immune responses in human and mouse T cells and blocks intracellular checkpoint signaling in T cells. Synonyms: BMS 502; BMS502. CAS No. 2407854-18-4. Molecular formula: C27H22F2N6O3. Mole weight: 516.50. | |
| BMS-505130 | BMS-505130 is a selective serotonin transport inhibitor with Ki of 0.18 nM. Ki value for binding to the norepinephrine is 4.6 mM and for dopamine transporters is 2.1 mM. Synonyms: BMS-505130; BMS 505130; BMS505130; UNII-E892TW82D9; E892TW82D9; 1H-Indole-5-carbonitrile, 3-((1S,2S)-2-((dimethylamino)methyl)cyclopropyl)-, (2Z)-2-butenedioate (1:1). Grade: 98%. CAS No. 859230-84-5. Molecular formula: C19H21N3O4. Mole weight: 355.39. | |
| BMS-505130 Free base | BMS-505130 is a potent and selective serotonin transport inhibitor with K(I) of 0.18 nM. Uses: A potent and selective serotonin transport inhibitor. Synonyms: BMS-505130; BMS 505130; BMS505130; 3-((1S,2S)-2-((dimethylamino)methyl)cyclopropyl)-1H-Indole-5-carbonitrile. Grade: ≥98%. CAS No. 468715-83-5. Molecular formula: C15H17N3. Mole weight: 239.32. | |
| BMS 509744 | BMS 509744. Group: Biochemicals. Grades: Purified. CAS No. 439575-02-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| BMS-509744 | BMS-509744 is a potent, selective and ATP competitive Itk inhibitor with an IC50 of 19 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 439575-02-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11092. | |
| BMS-509744 | BMS-509744 is a selective Itk inhibitor. It is useful for treatment of inflammatory and autoimmune diseases. Synonyms: BMS-509744; BMS 509744; BMS509744; CHEMBL209148. Grade: >98%. CAS No. 439575-02-7. Molecular formula: C32H41N5O4S2. Mole weight: 623.83. | |
| BMS-512148 | BMS-512148 Inhibitor. Uses: Scientific use. Product Category: T2389. CAS No. 461432-26-8. |  |
| BMS-520 | This active molecular is a selective S1P1 receptor agonist that originated by Bristol-Myers Squibb. BMS-520 shows really good efficacy in animal models of arthritis as well as in a mouse EAE (experimental autoimmune encephalomyelitis) model of multiple sclerosis. Agonism of S1P1 has been known to play an important role in lymphocyte trafficking from the thymus and secondary lymphoid organs, resulting in immunosuppression. Uses: Haematological malignancies; solid tumours. Synonyms: BMS-520; BMS 520; BMS520. 1-(4-(5-(3-phenyl-4-(trifluoromethyl)isoxazol-5-yl)-1,2,4-oxadiazol-3-yl)benzyl)azetidine-3-carboxylic acid. Grade: 98%. CAS No. 1236188-38-7. Molecular formula: C23H17F3N4O4. Mole weight: 470.41. | |
| BMS 536924 | BMS 536924. Group: Biochemicals. Grades: Purified. CAS No. 468740-43-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BMS-536924 | BMS-536924 is a potent small molecule inhibitor of IGF-IR, which shows antitumor activity in multiple tumor models, including sarcoma. Synonyms: BMS536924; BMS 536924; Insulin-like Growth Factor-1 Receptor Inhibitor; (S)-4-((2-(3-chlorophenyl)-2-hydroxyethyl)amino)-3-(4-methyl-6-morpholino-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one. Grade: 98%. CAS No. 468740-43-4. Molecular formula: C25H26ClN5O3. Mole weight: 479.96. | |
| BMS-536924 | BMS-536924 is an orally active, competitive and selective insulin-like growth factor receptor (IGF-1R) kinase and insulin receptor (IR) inhibitor with IC 50 s of 100 nM and 73 nM, respectively. BMS-536924 has anti-cancer activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 468740-43-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10262. | |
| BMS-536924 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BMS538158 | BMS538158 is a bio-active chemical compound developed by Bristol-Myers Squibb. Synonyms: BMS-538158; BMS 538158; Acetamide, 2-(2,2-dimethyl-5-oxo-1,3-dioxolan-4-ylidene)-N-((4-fluorophenyl)methyl)-N-methoxy-. Grade: 98%. CAS No. 543730-36-5. Molecular formula: C15H16FNO5. Mole weight: 309.29. | |
| BMS-538203 | BMS-538203 is a highly efficient HIV integrase inhibitor and antiviral agent. Synonyms: BMS-538203; BMS 538203; BMS538203. Grade: >98%. CAS No. 543730-41-2. Molecular formula: C12H12FNO5. Mole weight: 269.23. | |
| BMS-554417 | BMS-554417 is a novel inhibitor of IGF-IR, which inhibits IGF-IR and insulin receptor kinase activity and proliferation in vitro, with the IC50 for proliferation ranged from 120 nmol/L (Colo205) to >8.5 micromol/L (OV202). Uses: A novel inhibitor of igf-ir. Synonyms: BMS-554417; BMS 554417; BMS554417; 3-[4-[(2Z)-2-[4-[[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]-2-oxopyridin-3-ylidene]-7-methyl-1,3-dihydrobenzimidazol-5-yl]piperazin-1-yl]propanenitrile. Grade: ≥98%. CAS No. 468741-42-6. Molecular formula: C28H30ClN7O2. Mole weight: 532.04. | |
| BMS561392 | BMS561392 is a tumor necrosis factor-alpha (TNF alpha) converting enzyme inhibitor. It has the potential treatment of diseases characterized by overproduction of TNF alpha, such as rheumatoid arthritis (RA). It was developed by Bristol-Myers Squibb and was in clinic phase 2 trials, but now it is terminated. Uses: Bms561392 has the potential treatment of diseases characterized by overproduction of tnf alpha, such as rheumatoid arthritis (ra). Synonyms: BMS-561392; BMS561392; BMS 561392; DPC-333; DPC 333; DPC333. (αR,?3R)?-3-Amino-N-hydroxy-α-(2-methylpropyl)?-3-[4-[(2-methyl-4-quinolinyl)?methoxy]?phenyl]?-2-oxo-1-pyrrolidineacetamide?; BMS-561392; DPC-333; (2R)-2-[(3R)-3-amino-3-[4-[(2-methylquinolin-4-yl)methoxy]phenyl]-2-oxopyrrolidin-1-yl]-N-hyd. Grade: 98%. CAS No. 611227-74-8. Molecular formula: C27H32N4O4. Mole weight: 476.57. | |
| BMS-561392 formate | BMS-561392 formate is the formate form of BMS-561392 (HY-19667). BMS-561392 is a TNF alpha-converting enzyme (TACE) inhibitor. BMS-561392 is also an ADAM17 blocker. BMS-561392 can be used for research of inflammatory bowel disease[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DPC 333 formate. CAS No. 2922280-85-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-19667A. | |
| BMS-564929 | BMS-564929 is a novel androgen receptor (AR) modulator (Ki= 2.11 nM) which has been advanced to clinical trials for the treatment of age-related functional decline. Uses: Androgen receptor (ar) modulator. Synonyms: BMS-564929; BMS 564929; BMS564929. 4-[(7R,7aS)-7-hydroxy-1,3-dioxo-5,6,7,7a-tetrahydropyrrolo[1,2-c]imidazol-2-yl]-2-chloro-3-methylbenzonitrile. Grade: ≥98%. CAS No. 627530-84-1. Molecular formula: C14H12ClN3O3. Mole weight: 305.71. | |
| BMS-564929 | BMS-564929 is an androgen receptor (AR) agonist, binds to androgen receptor (AR) with a Ki of 2.11±0.16 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 627530-84-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-12111. | |
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