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| Product | Description | |
|---|---|---|
| Bathophenanthroline sulfonate | Diagnostic reagents. CAS No. 53744-42-6. Categories: 1,10-phenanthrolinedisulfonic acid, 4,7-diphenyl-. |  US, Austria, Lithuania |
| Batilol | 3-(Octadecyloxy)propane-1,2-diol is an endogenous metabolite. Uses: Scientific research. Group: Natural products. CAS No. 544-62-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 1 g. Product ID: HY-W011175. |  |
| Batimastat | Batimastat. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BB-94;(2R,3S)-N4-Hydroxy-N1-[(1S)-2-(methylamino)-2-oxo-1-(phenylmethyl)ethyl]-2-(2-methylpropyl)-3-[(2-thienylthio)methyl]butanediamide. Product Category: Thiophenes. Appearance: White to Off-White Solid. CAS No. 130370-60-4. Molecular formula: C23H31N3O4S2. Mole weight: 477.64. Purity: 95%+. Product ID: ACM130370604. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Batimastat | Batimastat is a potent broad spectrum MMP inhibitor with IC 50 of 3, 4, 4, 6, and 20 nM for MMP-1 , MMP-2 , MMP-9 , MMP-7 and MMP-3 , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BB94. CAS No. 130370-60-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13564. | |
| Batimastat | Batimastat. Group: Biochemicals. Alternative Names: (2R,3S)-N4-Hydroxy-N1-[(1S)-2-(methylamino)-2-oxo-1-(phenylmethyl)ethyl]-2-(2-methylpropyl)-3-[(2-thienylthio)methyl]-butanediamide; [2R-[1(S*),2R*,3S*]]-N4-hydroxy-N1-[2-(methylamino)-2-oxo-1-(phenylmethyl)ethyl]-2-(2-methylpropyl)-3-[(2-thienylthio)methyl]-butanediamide; (2S, 3R) -5-Methyl-3- [ [ (α S) -α - (methylcarbamoyl) phenethyl] carbamoyl] -2- [ (2-thienylthio) methyl] hexanohydroxamic Acid; BB 94. Grades: Highly Purified. CAS No. 130370-60-4. Pack Sizes: 5mg. Molecular Formula: C23H31N3O4S2, Molecular Weight: 477.64. US Biological Life Sciences. |  Worldwide |
| Batimastat | Batimastat (also known as BB-94) is a synthetic matrix metalloproteinase inhibitor that has shown antineoplastic and antiangiogenic activity in various tumor models. Batimastat acts as an inhibitor of metalloproteinase activity by binding the zinc ion in the active site of MMPs. Uses: Antineoplastic agents. Synonyms: (2S,3R)-N-Hydroxy-N'-[(2S)-1-methylamino-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)-2-(thiophen-2-ylsulfanylmethyl)butanediamide; BB94; BB-94; BB 94. Grades: 98%. CAS No. 130370-60-4. Molecular formula: C23H31N3O4S2. Mole weight: 477.638. |  |
| Batimastat | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Batimastat (BB-94) | Potent, broad spectrum matrix metalloprotease (MMP) inhibitor (IC?? values are 3, 4, 4, 6 and 20 nM for MMP -1, -2, -9, -7 and -3 respectively). Exhibits antiproliferative, anti-invasive and antimetastatic activity in human ovarian carcinoma xenografts in vivo. Group: Biochemicals. Alternative Names: (2R, 3S) -N4-Hydroxy-N1-[ (1S) -2- (methylamino) -2-oxo-1- (phenylmethyl) ethyl]-2- (2-methylpropyl) -3-[ (2-thienylthio) methyl]butanediamide. Grades: Highly Purified. CAS No. 130370-60-4. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Batimastat - CAS 130370-60-4 | Batimastat primarily used in Inhibition. Group: Fluorescence/luminescence spectroscopy. | |
| Batimastat-d3 | Batimastat-d3. Group: Biochemicals. Alternative Names: (2R,3S)-N4-Hydroxy-N1-[(1S)-2-(methylamino)-2-oxo-1-(phenylmethyl)ethyl]-2-(2-methylpropyl)-3-[(2-thienylthio)methyl]-butanediamide-d3; [2R-[1(S*),2R*,3S*]]-N4-hydroxy-N1-[2-(methylamino)-2-oxo-1-(phenylmethyl)ethyl]-2-(2-methylpropyl)-3-[(2-thienylthio)methyl]-butanediamide-d3; (2S, 3R) -5-Methyl-3- [ [ (α S) -α - (methylcarbamoyl) phenethyl] carbamoyl] -2- [ (2-thienylthio) methyl] hexanohydroxamic Acid-d3; BB 94-d3. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C23H28D3N3O4S2, Molecular Weight: 480.66. US Biological Life Sciences. | Worldwide |
| Batimastat sodium salt | Batimastat sodium salt (BB-94) is a potent, broad spectrum matrix metalloprotease (MMPs) inhibitor with IC50s of 3/4/20/6/4 nM for MMP-1/2/3/7/9 respectively. Synonyms: BB-94 sodium salt; BB 94 sodium salt; BB94 sodium salt. Grades: >98%. CAS No. 130464-84-5. Molecular formula: C23H30N3NaO4S2. Mole weight: 499.62. | |
| Batoclimab | Batoclimab is a human anti- FcRn monoclonal antibody. Batoclimab can be used for the research of autoimmune diseases mediated by pathogenic IgG antibodies [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: HBM9161; IMVT-1401. CAS No. 2187430-05-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99009. | |
| Batoclimab | Batoclimab is a humanized monoclonal antibody targeting the neonatal Fc receptor (FcRn). Batoclimab binds to and inhibits FcRn, thus blocking the recycling of IgG antibodies. Batoclimab can be used in the research of pathogenic IgG-mediated autoimmune diseases. Synonyms: HBM9161; IMVT-1401. CAS No. 2187430-05-1. | |
| Batoprotafib | Batoprotafib (TNO155) is a potent selective and orally active allosteric inhibitor of wild-type SHP2 ( IC 50 =0.011 μM). Batoprotafib has the potential for the study of RTK-dependent malignancies, especially advanced solid tumors [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TNO155. CAS No. 1801765-04-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136173. | |
| BA-TTB | BA-TTB. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N10,N10,N10',N10'-Tetra-tolyl-9,9'-bianthracene-10,10'-diamine. Product Category: Organic Light Emitting Diode (OLED). CAS No. 223735-62-4. Molecular formula: C56H44N2. Mole weight: 744.96 g/mol. Product ID: ACM223735624. Alfa Chemistry ISO 9001:2015 Certified. Categories: Batt (building insulation). | |
| Battery PE separator for Lithium Ion Battery | Battery PE separator for Lithium Ion Battery. Group: Battery materials. |  |
| Bauhinia Purpurea P.E. 10:1 | Bauhinia Purpurea P.E. 10:1. |  CA, FL & NJ |
| Baumycin A1 | Baumycin A1 is produced by the strain of Streptomyces sp. ME 130-A4. Synonyms: 5,12-Naphthacenedione, 8-acetyl-10-((3-amino-2,3,6-trideoxy-4-O-(3-hydroxy-1-(2-hydroxy-1-methylethoxy)butyl)-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, (8S-cis)-. CAS No. 64314-28-9. Molecular formula: C34H43NO13. Mole weight: 673.70. | |
| Baumycin B1 | Baumycin B1 is produced by the strain of Streptomyces sp. ME 130-A4. Synonyms: 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-8-acetyl-10-((3-amino-4-O-(1-(1-carboxyethoxy)-3-hydroxybutyl)-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-6,8,11-trihydroxy-1-methoxy-, (8S-cis)-; 3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-4-o-[1-(1-carboxyethoxy)-3-hydroxybutyl]-2,3,6-trideoxyhexopyranoside. CAS No. 64253-72-1. Molecular formula: C34H41NO14. Mole weight: 687.69. | |
| Baumycin C1 | Baumycin C1, an impurity of Daunorubicin and Doxorubicin, is an anthracycline antibiotic isolated from Streptomyces coeruleorubidus. Baumycin C1 shows antitumor activity. Synonyms: N-((2S,3S,4S,6R)-6-(((1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl)oxy)-3-hydroxy-2-methyltetrahydro-2H-pyran-4-yl)formamide; N-Formyldaunorubicin; NSC 227012; 5,12-Naphthacenedione, 8-acetyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-10-((2,3,6-trideoxy-3-(formylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, (8S-cis)-; (8S,10S)-8-Acetyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-10-[(3-(formylamino)-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-5,12-naphthacenedione. Grades: ≥95%. CAS No. 63084-42-4. Molecular formula: C28H29NO11. Mole weight: 555.53. | |
| Bauxite | Bauxite. Uses: For analytical and research use. Group: Process materials, geological, cement & soils. Pack Sizes: 100G. Catalog: APS00942. Format: Powder. Shipping: Room Temperature. | |
| Bauxite (Arkansas) | Bauxite (Arkansas). Uses: For analytical and research use. Group: Process materials, geological, cement & soils. Catalog: APS005997. Format: Powder. Shipping: Room Temperature. | |
| Bavachalcone | Bavachalcone inhibited osteoclast formation from precursor cells with the IC(50) of approximately 1.5 microg ml(-1). The activation of MEK, ERK, and Akt by receptor activator of nuclear factor kappaB ligand (RANKL), the osteoclast differentiation factor, was prominently reduced in the presence of bavachalcone. The induction of c-Fos and NFATc1, key transcription factors for osteoclastogenesis, by RANKL was also suppressed by bavachalcone. Bavachalcone exhibited a significant inhibitory effect on baculovirus-expressed BACE-1 in vitro. Bavachalcone had stronger inhibition on UGT1A1 and UGT1A7 than corylin which did not inhibit UGT1A1, UGT1A3, UGT1A7, UGT1A8, UGT1A10, and UGT2B4. Data fitting using Dixon and Lineweaver-Burk plots demonstrated the noncompetitive inhibition of bavachalcone against UGT1A1 and UGT1A7-mediated 4-MU glucuronidation reaction. The values of inhibition kinetic parameters (Ki) were 5.41 μ M and 4.51μ M for UGT1A1 and UGT1A7, respectively. Synonyms: Broussochalcone B. Grades: >98%. CAS No. 28448-85-3. Molecular formula: C20H20O4. Mole weight: 324.37. | |
| Bavachin | Bavachin. Group: Biochemicals. Alternative Names: Corylifolin. Grades: Plant Grade. CAS No. 19879-32-4. Pack Sizes: 20mg. Molecular Formula: C20H20O4, Molecular Weight: 324.37. US Biological Life Sciences. | Worldwide |
| Bavachinin A | Bavachinin A. Group: Biochemicals. Grades: Plant Grade. CAS No. 19879-30-2. Pack Sizes: 20mg. US Biological Life Sciences. | Worldwide |
| Bavdegalutamide | It is an orally active, specific androgen receptor (AR) PROTAC degrader, and is also an antineoplastic agent. It promotes ubiquitination and degradation of AR and can be used for the research of prostate cancer. Synonyms: 3-Pyridazinecarboxamide, N-[trans-4-(3-chloro-4-cyanophenoxy)cyclohexyl]-6-[4-[[4-[2-(2,6-dioxo-3-piperidinyl)-6-fluoro-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-1-piperazinyl]methyl]-1-piperidinyl]-; ARV-110; N-((1r,4r)-4-(3-chloro-4-cyanophenoxy)cyclohexyl)-6-(4-((4-(2-(2,6-dioxopiperidin-3-yl)-6-fluoro-1,3-dioxoisoindolin-5-yl)piperazin-1-yl)methyl)piperidin-1-yl)pyridazine-3-carboxamide; N-[trans-4-(3-Chloro-4-cyanophenoxy)cyclohexyl]-6-[4-[[4-[2-(2,6-dioxo-3-piperidinyl)-6-fluoro-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-1-piperazinyl]methyl]-1-piperidinyl]-3-pyridazinecarboxamide; ARV 110; ARV110; rac-N-[trans-4-(3-chloro-4-cyanophenoxy)cyclohexyl]-6-{4-[(4-{2-[(3R)-2,6-dioxopiperidin-3-yl]-6-fluoro-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl}piperazin-1-yl)methyl]piperidin-1-yl}pyridazine-3-carboxamide. Grades: 98% by HPLC. CAS No. 2222112-77-6. Molecular formula: C41H43ClFN9O6. Mole weight: 812.29. | |
| Bavdegalutamide | Bavdegalutamide, also known as ARV-110, effectively targets the wild type Androgen Receptor (AR) and certain genomic alterations of the AR (amplification, T878A, H875Y, F877L, M895V, but not L702H or AR-V7) for degradation in both enzalutamide sensitive and resistant preclinical models. ARV-110 showed promising anti-tumor activity in heavily pretreated men with metastatic castration-resistant prostate cancer (mCRPC). Uses: Designed for use in research and industrial production. Additional or Alternative Names: ARV-110; ARV 110; ARV110; Bavdegalutamide. Product Category: Others. Appearance: Solid powder. CAS No. 2222112-77-6. Molecular formula: C41H43ClFN9O6. Mole weight: 812.3. Purity: >98%. IUPACName: N-((1r,4r)-4-(3-chloro-4-cyanophenoxy)cyclohexyl)-6-(4-((4-(2-(2,6-dioxopiperidin-3-yl)-6-fluoro-1,3-dioxoisoindolin-5-yl)piperazin-1-yl)methyl)piperidin-1-yl)pyridazine-3-carboxamide. Canonical SMILES: ClC1=CC(O[C@H]2CC[C@@H](CC2)NC(C3=CC=C(N=N3)N4CCC(CC4)CN5CCN(CC5)C6=CC(C(N7C8CCC(NC8=O)=O)=O)=C(C=C6F)C7=O)=O)=CC=C1C#N. Product ID: ACM2222112776. Alfa Chemistry ISO 9001:2015 Certified. | |
| Bavdegalutamide | Bavdegalutamide Inhibitor. Uses: Scientific use. Product Category: T22263. CAS No. 2222112-77-6. |  |
| Bavisant | Bavisant (JNJ-31001074) is an orally active, potent, brain-penetrating and highly selective antagonist of the histamine H 3 receptor. Bavisant can be used for attention-deficit hyperactivity disorder (ADHD) research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ-31001074. CAS No. 929622-08-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-14880. | |
| Bavisant | Bavisant is a highly selective, orally active antagonist of the human H3 receptor. It is a novel mechanism of action, involving wakefulness and cognition. It has potential to be used as a treatment for ADHD. It was developed by Johnson & Johnson and has completed a phase II ADHD trial, but there has been no progress. Uses: Bavisant has potential to be used as a treatment for adhd. Synonyms: JNJ 31001074;JNJ-31001074; JNJ31001074; (4-Cyclopropylpiperazin-1-yl)-[4-(morpholin-4-ylmethyl)phenyl]methanone. Grades: >98%. CAS No. 929622-08-2. Molecular formula: C19H27N3O2. Mole weight: 329.44. | |
| Bavisant dihydrochloride | Bavisant dihydrochloride is the dihydrochloride form of Bavisant, which is a highly selective, orally active antagonist of the human H3 receptor. It may be used as a treatment for ADHD. It was developed by Johnson & Johnson and has completed a phase II ADHD trial, but there has been no progress. Uses: Bavisant dihydrochloride may be used as a treatment for adhd. Synonyms: JNJ 31001074 dihydrochloride; JNJ-31001074 dihydrochloride; JNJ31001074 dihydrochloride; (4-Cyclopropylpiperazin-1-yl)(4-(morpholin-4-ylmethyl)phenyl)methanone dihydrochloride;Methanone, (4-cyclopropyl-1-piperazinyl)(4-(4-morpholinylmethyl)phenyl)-, hydrochloride (1:2). Grades: >98 %. CAS No. 929622-09-3. Molecular formula: C19H29Cl2N3O2. Mole weight: 402.36. | |
| Bavisant dihydrochloride hydrate | The dihydrochloride hydrate salt form of Bavisant which is an orally bioavaliable and selective H3 receptor antagonist that could probably useful in the treatment of Attention-deficit hyperactivity disorder(ADHD). It is known to have been completed the Ph. Uses: The dihydrochloride hydrate salt form of bavisant which is a h3 receptor antagonist that could probably useful in the treatment of attention-deficit hyperactivity disorder(adhd). Synonyms: Bavisant dihydrochloride; JNJ-31001074-AAC; JNJ 31001074-AAC; JNJ31001074-AAC; UNII-C1H7H5X3RE; BAVISANT DIHYDROCHLORIDE; JNJ-31001074-AAC; 1103522-80-0; Bavisant dihydrochloride (USAN); Bavisant dihydrochloride [USAN]. Grades: 98%. CAS No. 1103522-80-0. Molecular formula: C19H31Cl2N3O3. Mole weight: 420.37. | |
| Bavisant dihydrochloride hydrate | Bavisant dihydrochloride hydrate (JNJ31001074AAC) is an orally active, potent, brain-penetrating and highly selective antagonist of the histamine H 3 receptor. Bavisant dihydrochloride hydrate can be used for attention-deficit hyperactivity disorder (ADHD) research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ31001074AAC; JNJ31001074 dihydrochloride hydrate. CAS No. 1103522-80-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-14880B. | |
| Bavituximab | Bavituximab (Anti-Human Phosphatidylserine Recombinant Antibody) is a phosphatidylserine (PS)-targeting monoclonal antibody, suppresses tumor growth by targeting tumor vasculature and reactivating antitumor immunity. Bavituximab plus Paclitaxel (HY-B0015) and Carboplatin (HY-17393), have enhanced inhibition on non-small-cell lung cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human Phosphatidylserine Recombinant Antibody. CAS No. 648904-28-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99279. | |
| BAW2881 | BAW 2881 is a VEGFR (vascular endothelial growth factor receptor) inhibitor (IC50 = 0.82, 0.037, and 0.42 μM for VEGFR1, 2, and 3, respectively).It can inhibit proliferation, migration, and tube formation by human umbilical vein endothelial cells and lymphatic endothelial cells in vitro. Synonyms: BAW2881; BAW-2881; BAW 2881; NVP-BAW2881; NVP-BAW-2881; NVP-BAW 2881. 6-((2-aminopyrimidin-4-yl)oxy)-N-(3-(trifluoromethyl)phenyl)-1-naphthamide. Grades: 98%. CAS No. 861875-60-7. Molecular formula: C22H15F3N4O2. Mole weight: 424.38. | |
| Bax channel blocker | A direct allosteric inhibitor of BAX. Synonyms: BAI1. Grades: >98 %. CAS No. 335165-68-9. Molecular formula: C19H21Br2N3O. Mole weight: 467.20. | |
| Bax channel blocker | Bax channel blocker. Group: Biochemicals. Grades: Purified. CAS No. 329349-20-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Baxdrostat | Baxdrostat is an aldosterone synthase inhibitor. Synonyms: N-[(8R)-4-(1-methyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-5,6,7,8-tetrahydroisoquinolin-8-yl]propanamide; (R)-N-(4-(1-methyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-5,6,7,8-tetrahydroisoquinolin-8-yl)propionamide; N-[(8R)-4-(1-Methyl-2-oxo-1,2,3,4-tetrahydro-6-quinolinyl)-5,6,7,8-tetrahydro-8-isoquinolinyl]propanamide; Propanamide, N-[(8R)-5,6,7,8-tetrahydro-4-(1,2,3,4-tetrahydro-1-methyl-2-oxo-6-quinolinyl)-8-isoquinolinyl]-. CAS No. 1428652-17-8. Molecular formula: C22H25N3O2. Mole weight: 363.45. | |
| Baxdrostat | Baxdrostat is a aldosterone synthase inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CIN-107. CAS No. 1428652-17-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132809. | |
| BAX, GST tagged human | recombinant, expressed in E. coli, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| BAX Inhibiting Peptide V5 | ?97% (HPLC), lyophilized powder. Group: Fluorescence/luminescence spectroscopy. | |
| Bax inhibitor peptide, negative control | A negative control peptide for the Bax inhibitor peptide V5, which inhibits Bax translocation to mitochondria and Bax-mediated apoptosis in vitro. Synonyms: L-isoleucyl-L-prolyl-L-methionyl-L-isoleucyl-L-lysine. Grades: >98%. CAS No. 1315378-74-5. Molecular formula: C28H52N6O6S. Mole weight: 600.82. | |
| Bax inhibitor peptide V5 | Bax inhibitor peptide V5, a peptide inhibitor, as a pro-apoptotic member of Bcl-2 family proteins and plays an important role in mitochondria-dependent apoptosis. Uses: A pro-apoptotic member of bcl-2 family proteins. Synonyms: L-Valyl-L-prolyl-L-methionyl-L-leucyl-L-lysine. Grades: ≥97% by HPLC. CAS No. 579492-81-2. Molecular formula: C27H50N6O6S. Mole weight: 586.8. | |
| Bax inhibitor peptide V5 acetate | Bax inhibitor peptide V5 acetate, a Bax-mediated apoptosis inhibitor, is a pro-apoptotic member of Bcl-2 family proteins and plays an important role in mitochondria-dependent apoptosis. It is used in cancer treatment. Synonyms: BIP-V5 acetate; H-Val-Pro-Met-Leu-Lys-OH.CH3CO2H; VPMLK acetate; L-valyl-L-prolyl-L-methionyl-L-leucyl-L-lysine acetic acid. Grades: ≥95%. CAS No. 2760881-58-9. Molecular formula: C29H54N6O8S. Mole weight: 646.85. | |
| Bay 02752 | Bay 02752 is a bio-active molecular, but no detailed information has been published yet. Synonyms: Bay-02752; Bay 02752; Bay02752; N,N'-(1,11-Undecanediyl) bis (2,3-dihydro-2-methyl-1H-indole-1-carboxamide). Grades: 98%. CAS No. 78991-74-9. Molecular formula: C31H44N4O2. Mole weight: 504.71. | |
| BAY-1142524 | BAY-1142524 is a chymase inhibitor. Chymase is an enzyme that modulates the production of proteins playing a role in adverse cardiac tissue remodeling and fibrogenesis. Study shows that BAY-1142524 could suppress the abnormal cardiac tissue remodeling after myocardial infarction (MI) and improves cardiac function. Uses: Abnormal cardiac tissue remodeling reduction. Synonyms: BAY-1142524; BAY 1142524; BAY1142524. | |
| BAY-1143572 | BAY 1143572 is a highly selective, potent and orally available inhibitor ofPTEFb/CDK9 and shows convincing anti-tumor activity in multiple xenograft models by the induction of apoptosis. Synonyms: 4-(4-fluoro-2-methoxyphenyl)-N-[3-[(methylsulfonimidoyl)methyl]phenyl]-1,3,5-triazin-2-amine; BAY1143572; BAY 1143572; BAY-1143572. Atuveciclib. CAS No. 1414943-88-6. Molecular formula: C18H18FN5O2S. Mole weight: 387.43. | |
| Bay 11-7082 | ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. | |
| BAY 11-7082 | IkappaBalpha kinase inhibitor. NF-kappaB inhibitor. Potential anti-inflammatory agent. Apoptosis inducer. Inhibits the release of proinflammatory cytokines. Inflammasome inhibitor Inhibits platelet aggregation. Group: Biochemicals. Alternative Names: (E)-3-(4-Methylphenylsulfonyl)-2-propenenenitrile. Grades: Highly Purified. CAS No. 19542-67-7. Pack Sizes: 10mg, 50mg. Molecular Formula: C10H9NO2S. US Biological Life Sciences. | Worldwide |
| BAY 11-7082 | BAY 11-7082 is an IκBα phosphorylation and NF-κB inhibitor. BAY 11-7082 selectively and irreversibly inhibits the TNF-α-induced phosphorylation of IκB-α, and decreases NF-κB and expression of adhesion molecules. BAY 11-7082 inhibits ubiquitin-specific protease USP7 and USP21 ( IC 50 =0.19, 0.96 μM, respectively). BAY 11-7082 inhibits gasdermin D (GSDMD) pore formation in liposomes and inflammasome-mediated pyroptosis and IL-1β secretion in human and mouse cells [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 11-7821. CAS No. 19542-67-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13453. | |
| BAY 11-7082 | BAY 11-7082 completely and specifically abrogates NF-κB DNA binding, downregulating the NF-κB-inducible cytokine IL-6 and inducing apoptosis. Synonyms: BAY 11-7821; BAY 11-7082; BAY11-7082; BAY-11-7082; BAY 117082; BAY117082; BAY-117082. Grades: >98%. CAS No. 19542-67-7. Molecular formula: C10H9NO2S. Mole weight: 207.25. | |
| BAY 11-7082 ((E)-3-(4-Methylphenylsulfonyl)-2-propenenenitrile) | Potential anti-inflammatory agent. Selectively and irreversibly inhibits NF-kB activation by blocking TNF-a-induced phosphorylation of IkB-a without affecting constitutive IkB-a phosphorylation. Inhibits the TNF-a-induced surface expression of adhesion molecules ICAM-1, VCAM-1, and E-selectin in human endothelial cells with IC50 values of 5-10uM. Group: Biochemicals. Grades: Highly Purified. CAS No. 195462-67-7. Pack Sizes: 10mg, 50ug. US Biological Life Sciences. | Worldwide |
| Bay 11-7085 | Bay 11-7085. Group: Biochemicals. Grades: Purified. CAS No. 196309-76-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Bay 11-7085 | BAY 11-7085 is an irreversible inhibitor of TNFα-induced IκBα phosphorylation with IC50 of 10 μM. Synonyms: Bay 11-7085; Bay-11-7085; Bay11-7085; Bay 117085; Bay-117085; Bay117085. Grades: >98%. CAS No. 196309-76-9. Molecular formula: C13H15NO2S. Mole weight: 249.33. | |
| Bay 11-7085 | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| Bay 11-7821 | Bay 11-7821. Group: Biochemicals. Grades: Purified. CAS No. 19542-67-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| BAY 1214784 | BAY 1214784 is a potent, selective, and orally active antagonist of the human gonadotropin-releasing hormone receptor ( hGnRH-R ). BAY 1214784 is a spiroindoline derivative compound. BAY 1214784 effectively lowers plasma luteinizing hormone levels by up to 49%, at the same time being associated with low pharmacokinetic variability and good tolerability. BAY 1214784 has the potential for the research of uterine fibroids [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1631164-25-4. Pack Sizes: 5 mg. Product ID: HY-144863. | |
| BAY-1217389 | BAY-1217389, an imidazopyridazin derivative, has been found to be a TTK protein inhibitor that could probably be effective as an antineoplastic agent and also be a potentialcell death stimulant. It is still under Phase I trail for solid tumor. Synonyms: BAY1217389; BAY-1217389; BAY 1217389; N-cyclopropyl-4-(6-(2,3-difluoro-4-methoxyphenoxy)-8-((3,3,3-trifluoropropyl)amino)imidazo[1,2-b]pyridazin-3-yl)-2-methylbenzamide. Grades: 98%. CAS No. 1554458-53-5. Molecular formula: C27H24F5N5O3. Mole weight: 561.51. | |
| BAY-1251152 | BAY-1251152 is a potent and selective CDK9 inhibitor with anti-tumor activity. Synonyms: BAY 1251152; BAY1251152; (+)-BAY-1251152. Grades: ≥98% by HPLC. CAS No. 1610358-56-9. Molecular formula: C19H18F2N4O2S. Mole weight: 404.4. | |
| BAY 1436032 | BAY-1436032 is a highly selective, potent and orally available inhibitor of mutant Isocitrate Dehydrogenase 1 (mIDH1). It is a double-digit nanomolar and selective pan-inhibitor of the enzymatic activity of various IDH1-R132X mutants in vitro and displays potent inhibition of 2-HG release (nanomolar range) in patient derived and engineered cell lines expressing different IDH1 mutants. BAY 1436032 strongly reduces 2-HG (2-hydroxyglutarate) levels in cells carrying IDH1-R132H, -R132C, -R132G, -R132S and -R132L mutations. BAY 1436032 showed a favourable selectivity profile against wtIDH1/2 and a large panel of off-targets in vitro. Synonyms: 3-(2-[[4-(Trifluoromethoxy)phenyl]amino]-1-[(1R,5R)-3,3,5-trimethylcyclohexyl]-1H-benzimidazol-5-yl)propanoic Acid; BAY-1436032. Grades: ≥98%. CAS No. 1803274-65-8. Molecular formula: C26H30F3N3O3. Mole weight: 489.53. | |
| BAY-1436032 | BAY-1436032 is a potent, selective and orally available inhibitor of mutant Isocitrate Dehydrogenase 1 (mIDH1). BAY 1436032 is a double-digit nanomolar and selective pan-inhibitor of the enzymatic activity of various IDH1-R132X mutants in vitro and displayed potent inhibition of 2-HG release (nanomolar range) in patient derived and engineered cell lines expressing different IDH1 mutants. In line with the proposed mode of action, a concentration-dependent lowering of 2-HG was observed in vitro accompanied by differentiation and maturation of mIDH1 tumor cells. Furthermore, BAY 1436032 showed a favourable selectivity profile against wtIDH1/2 and a large panel of off-targets in vitro. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BAY-1436032; BAY 1436032; BAY1436032. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1803274-65-8. Molecular formula: C26H30F3N3O3. Mole weight: 489.54. Purity: >98%. IUPACName: 3-(2-((4-(trifluoromethoxy)phenyl)amino)-1-((1R,5R)-3,3,5-trimethylcyclohexyl)-1H-benzo[d]imidazol-5-yl)propanoic acid. Canonical SMILES: O=C(O)CCC1=CC=C2N([C@H]3CC(C)(C)C[C@@H](C)C3)C(NC4=CC=C(OC(F)(F)F)C=C4)=NC2=C1. Product ID: ACM1803274658. Alfa Chemistry ISO 9001:2015 Certified. | |
| BAY-179 | BAY-179 is a potent, selective, and species cross-reactive OXPHOS complex I inhibitor. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BAY-179; BAY 179; BAY179. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2764880-87-5. Molecular formula: C23H21N5OS. Mole weight: 415.52. Purity: >98%. IUPACName: 2-(1-((1H-Imidazo[4,5-b]pyridin-2-yl)methyl)piperidin-4-yl)-4-(benzofuran-2-yl)thiazole. Canonical SMILES: C1(C2CCN(CC3=NC4=NC=CC=C4N3)CC2)=NC(C5=CC6=CC=CC=C6O5)=CS1. Product ID: ACM2764880875. Alfa Chemistry ISO 9001:2015 Certified. Categories: BAY 1896953. | |
| BAY-1895344 | BAY-1895344 is a selective ATR (ataxia-telangiectasia and Rad3 related protein) inhibitor that inhibits proliferation of a broad spectrum of human tumor cell lines (median IC50 = 78 nM). BAY-1895344 is developed for the treatment of patients with advanced solid tumors and lymphomas, and it is undergoing a phase I clinical trial of safety and tolerability for cancer patients. Uses: A selective atr (ataxia-telangiectasia and rad3 related protein) inhibitor used for the treatment of advanced solid tumors and lymphomas. Synonyms: BAY-1895344; BAY 1895344; BAY1895344; (R)-3-methyl-4-(4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl)morpholine. Grades: ≥98 %. CAS No. 1876467-74-1. Molecular formula: C20H21N7O. Mole weight: 375.181. | |
| BAY-1895344 hydrochloride | BAY-1895344 is a potent, orally available and highly selective ATR inhibitor (IC50= 7 nM), which potently inhibits proliferation of a broad spectrum of human tumor cell lines (median IC50 = 78 nM). In cellular mechanistic assays BAY 1895344 potently inhibited hydroxyurea-induced H2AX phosphorylation (IC50 = 36 nM). Synonyms: Elimusertib hydrochloride; BAY 1895344 hydrochloride; BAY1895344 hydrochloride; 2-[(3R)-3-Methyl-4-morpholinyl]-4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-3-yl)-1,7-naphthyridine hydrochloride; 2-[(3R)-3-methylmorpholin-4-yl]-4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridine hydrochloride; Bay 1895344; 1,7-Naphthyridine, 2-[(3R)-3-methyl-4-morpholinyl]-4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-3-yl)-, hydrochloride (1:1). Grades: ≥95%. Molecular formula: C20H22ClN7O. Mole weight: 411.89. | |
| BAY 19-8004 | BAY 19-8004 is a selective inhibitor of phosphodiesterase-4 (PDE4) used for the treatment of COPD. Uses: The treatment of copd. Synonyms: Lirimilast; SMR004703312; [3-(carbamoylamino)-2-(2,4-dichlorobenzoyl)-1-benzofuran-6-yl] methanesulfonate. Grades: 98%. CAS No. 329306-27-6. Molecular formula: C17H12Cl2N2O6S. Mole weight: 443.26. | |
| BAY-218 | BAY-218 (AHR antagonist 1) is an aryl hydrocarbon receptor (AHR) antagonist. BAY-218 has AHR inhibitory activity with an IC 50 of 39.9 nM in in U87 glioblastoma cells. BAY-218 can be used for the research of cancer or conditions with dysregulated immune responses [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AHR antagonist 1. CAS No. 2162982-11-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111449. | |
| BAY-218 | BAY-218, which is known as BAY-2335218, is a potent and selective small-molecule AhR inhibitor with an IC50 of 39.9 nM in human cell line. It is a new modality to counteract tumor immunosuppression. Synonyms: BAY 218; BAY218; BAY-2335218; BAY 2335218; BAY2335218; (S)-6-(4-chlorophenyl)-2-(3-fluorophenyl)-N-(1-hydroxypropan-2-yl)-3-oxo-2,3-dihydropyridazine-4-carboxamide; AHR antagonist 1. Grades: ≥98%. CAS No. 2162982-11-6. Molecular formula: C20H17ClFN3O3. Mole weight: 401.82. | |
| BAY-2402234 | BAY-2402234 is a potent and selective dihydroorotate dehydrogenase (DHODH) inhibitor for the treatment of myeloid malignancies. BAY 2402234 is a selective low-nanomolar inhibitor of human DHODH enzymatic activity. In vitro, it potently inhibits proliferation of AML cell lines in the sub-nanomolar to low-nanomolar range. BAY 2402234 induces differentiation of AML cell lines also in a sub-nanomolar to low-nanomolar range, demonstrating the anticipated mode of action in cellular mechanistic assays. In vivo, BAY 2402234 exhibits strong in vivo anti-tumor efficacy in monotherapy in several subcutaneous and disseminated AML xenografts as well as AML patient-derived xenograft (PDX) models. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BAY-2402234; BAY 2402234; BAY2402234; Orludodstat; Orludodstatum. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2225819-06-5. Molecular formula: C21H18ClF5N4O4. Mole weight: 520.84. Purity: >98%. IUPACName: (S)-N-(2-chloro-6-fluorophenyl)-4-(4-ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)-5-fluoro-2-((1,1,1-trifluoropropan-2-yl)oxy)benzamide. Canonical SMILES: FC1=C(NC(C2=CC(F)=C(N3N=C(CO)N(CC)C3=O)C=C2O[C@@H](C)C(F)(F)F)=O)C(Cl)=CC=C1. Product ID: ACM2225819065. Alfa Chemistry ISO 9001:2015 Certified. | |
| BAY 2416964 | BAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1, example 192, has an IC 50 of 341 nM. BAY 2416964 has the potential for solid tumors treatment [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2242464-44-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135829. | |
| BAY 2416964 | BAY 2416964 is a potent, orally active, aromatic hydrocarbon receptor (AHR) antagonist, which has the potential to treat solid tumors. Synonyms: BAY2416964; (S)-6-(4-Chlorophenyl)-N-(1-Hydroxypropan-2-Yl)-2-(1-Methyl-1H-Pyrazol-4-Yl)-3-Oxo-2,3-Dihydropyridazine-4-Carboxamide. Grades: ≥98% by HPLC. CAS No. 2242464-44-2. Molecular formula: C18H18ClN5O3. Mole weight: 387.8. | |
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