American Chemical Suppliers
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Product | Description | |
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BAY-41-8543 Quick inquiry Where to buy Suppliers range | BAY-41-8543, with antihypertensive, is a heme-dependent stimulator of NO-independent guanylyl cyclase (sGC). In vivo, BAY 41-8543 decreases blood pressure dose-dependently, prolongs bleeding time, and reduces thrombosis. In vitro, BAY 41-8543 induces relaxation of aorta, saphenous arteries, coronary arteries and veins. Synonyms: -[1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]-5-morpholin-4-ylpyrimidine-4,6-diamine; BAY-41-8543; BAY418543; BAY41-8543; UNII-323T2C09SG. Grades: 95%. CAS No. 256498-66-5. Molecular formula: C21H21FN8O. Mole weight: 420.44. | |
BAY-545 Quick inquiry Where to buy Suppliers range | BAY-545 is a potent and selective A2B adenosine receptor antagonist with IC50 of 59 nM. Synonyms: GTPL11224; EX-A2960; BAY 545; BAY545. Grades: 98%. CAS No. 1699717-32-2. Molecular formula: C18H22F3N3O4S. Mole weight: 433.4. | |
Bay 55-9837 Quick inquiry Where to buy Suppliers range | Bay 55-9837. Group: Biochemicals. Grades: Purified. CAS No. 463930-25-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Bay 55-9837 Quick inquiry Where to buy Suppliers range | Bay 55-9837 is a selective VPAC2 receptor agonist (EC50 = 0.4, 100 and >1000 nM for VPAC2, VPAC1 and PAC1, respectively in a cAMP accumulation assay; IC50=60, 8700 and >10000 nM for VPAC2, VPAC1 and PAC1, respectively in a competition binding assay). It promotes glucose-dependent insulin secretion in isolated human pancreatic islets and inhibits HIV-1 viral replication. CAS No. 463930-25-8. Molecular formula: C167H270N52O46. Mole weight: 3742.29. | |
BAY 56-3722 Quick inquiry Where to buy Suppliers range | BAY 56-3722 is a water-soluble camptothecin derivative conjugated to a carbohydrate moiety exhibiting antineoplastic activity. BAY 56-3722 stabilizes the topoisomerase I-DNA covalent complex and forms an enzyme-drug-DNA ternary complex. The peptide carbohydrate moiety of this agent stabilizes the lactone form of camptothecin in blood. Synonyms: BAY-563722; BAY56 3722; BAY 38-3441; BAY 38 344; (S)-4-ethyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl ((4-(((2R,3S,4R,5R,6S)-3,5-dihydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)phenyl)carbamothioyl)-L-histidyl-L-valinate. CAS No. 215604-75-4. Molecular formula: C45H50ClN7O11S. Mole weight: 895.98. | |
BAY 56-3722 hydrochloride Quick inquiry Where to buy Suppliers range | BAY 56-3722, a water-soluble camptothecin derivative, is a DNA-Intercalating drug that stabilizes the topoisomerase I-DNA covalent complex and forms an enzyme-drug-DNA ternary complex. Synonyms: BAY 56-3722; BAY56-3722; BAY-56-3722; N-[4- (6-Deoxy-3-O-methyl-beta-L-galactopyranosyloxy) phenylaminothiocarbonyl]-L-histidyl-L-valine 4(S)-ethyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl ester hydrochloride; N-[4-(3-O-Methyl-beta-L-fucopyranosyloxy)p; Afeletecan hydrochloride; BAY 38-3441; L-Valine, N- ( ( (4- ( (6-deoxy-3-O-methyl-beta-L-galactopyranosyl) oxy) phenyl) amino) thioxomethyl) -L-histidyl-, (4S)-4-ethyl-3,4,12,14-tetrahydro-3,14-dioxo-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinolin-4-yl ester, hydrochloride (1:1); 215604-75-4 (BAY 56-3722 free base); 215604-74-3 (BAY 56-3722 HCl salt; 215604-66-3 (diastereomeric mixture). Grades: >98%. CAS No. 215604-74-3. Molecular formula: C45H49N7O11S.HCl. Mole weight: 932.447. | |
BAY-57-1293 Quick inquiry Where to buy Suppliers range | BAY 57-1293 represents a new class of potent inhibitors of herpes simplex virus (HSV) that target the virus helicase primase complex. Potent helicase-primase inhibitor (HPI) effective against herpes simplex virus (HSV) infections with IC50 value of 20 nM for inhibition of the replication of both HSV-1 and HSV-2 in Vero cells, and ED50 value of 0.5 mg/kg for both HSV-1 and HSV-2 in the murine lethal challenge model of disseminated herpes. Uses: For research used only. Synonyms: Pritelivir; BAY-57-1293; BAY 57-1293; BAY-57 1293; BAY 57 1293; BAY571293; AIC316; AIC 316; AIC-316. Grades: 98%. CAS No. 348086-71-5. Molecular formula: C18H18N4O3S2. Mole weight: 402.49. | |
BAY 58-2667 hydrochloride Quick inquiry Where to buy Suppliers range | Nitric oxide (NO)- and heme-independent soluble guanylyl cyclase activator. Shows potent cardiovascular effects. Improves cardiopulmonary hemodynamics in patients with acute decompensated heart failure. Exhibits potent vasodilator and antiplatelet activity. Anti-aggregating agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 1240669-95-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
BAY 58-2667 hydrochloride Quick inquiry Where to buy Suppliers range | BAY 58-2667, also known as Cinaciguat, is a potent nitric oxide (NO)-independent soluble guanylyl cyclase (sGC) activator (EC50 = 6.4 nM). It exhibits antihypertensive effects in vivo and is used in the treatment of acute decompensated heart failure (ADHF). Synonyms: 5-Fluoro-2-methoxy-[1-[2-[(methylsulfonyl)amino]ethyl]-4-piperidinyl]-1H-indole-3-methylcarboxylate Sulfamate; Cinaciguat HCl; BAY 582667 HCl; BAY-582667 HCl; BAY582667 HCl; BAY 58-2667 HCl; BAY-58-2667 HCl; BAY58-2667 HCl; Cinaciguat HCl. Grades: ≥98% by HPLC. CAS No. 646995-35-9. Molecular formula: C36H39NO5.HCl. Mole weight: 602.16. | |
BAY-588 Quick inquiry Where to buy Suppliers range | BAY-588 is a glucose transporter inhibitor and derivative of BAY-876. BAY-876 is a potent, highly selective, cell-permeable inhibitor of glucose transporter GLUT1. It selectively inhibits glucose transporter 4 (Glut4), Glut1, and Glut3 over Glut2 with IC50 values of 0.5, 1.18, 5.47, and >10 μM, respectively, in CHO cells expressing human recombinant transporters. Synonyms: BAY 588; BAY588; N4-[1-[[4-(1,1-Dimethylethyl)phenyl]methyl]-5-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-7-fluoro-2,4-quinolinedicarboxamide. Grades: ≥98%. CAS No. 1799759-24-2. Molecular formula: C27H25F4N5O2. Mole weight: 527.5. | |
BAY 59-3074 Quick inquiry Where to buy Suppliers range | Bay 59-3074 is a novel, selective CB1/CB2 receptor partial agonist(Ki values are 48.3 and 45.5 nM at human CB1 and CB2 receptors respectively). Uses: Novel cb1/cb2 receptor partial agonist. Synonyms: BAY-59-3074; BAY 59-3074; BAY59-30743-[2-Cyano-3-(trifluoromethyl)phenoxy]phenyl 4,4,4-trifluoro-1-butanesulfonic acid ester. Grades: ≥98%. CAS No. 406205-74-1. Molecular formula: C18H13F6NO4S. Mole weight: 453.358. | |
BAY-598 Quick inquiry Where to buy Suppliers range | BAY-598 is a potent, peptide-competitive chemical probe for SET and MYND domain-containing protein 2 (SMYD2), IC50 values of 27 nM and 58 nM for biochemical and cellular activity, respectively. BAY 598 exhibits 100-fold selectivity for SMYD2 over other histone methyltransferases and non-epigenetic enzymes. Synonyms: (S, E) -N- (1- (N'-cyano-N- (3- (difluoromethoxy) phenyl) carbamimidoyl) -3- (3, 4-dichlorophenyl) -4, 5-dihydro-1H-pyrazol-4-yl) -N-ethyl-2-hydroxyacetamide; BAY-598; BAY 598; BAY598. CAS No. 1906919-67-2. Molecular formula: C22H20Cl2F2N6O3. Mole weight: 525.33. | |
BAY-598 R-isomer Quick inquiry Where to buy Suppliers range | BAY-598 R-isomer is the R-isomer of BAY589 which is a potent, peptide-competitive chemical probe for SET and MYND domain-containing protein 2 (SMYD2), IC50 values of 27 nM and 58 nM for biochemical and cellular activity, respectively. BAY 598 exhibits 100-fold selectivity for SMYD2 over other histone methyltransferases and non-epigenetic enzymes. Synonyms: (R, E) -N- (1- (N'-cyano-N- (3- (difluoromethoxy) phenyl) carbamimidoyl) -3- (3, 4-dichlorophenyl) -4, 5-dihydro-1H-pyrazol-4-yl) -N-ethyl-2-hydroxyacetamide; BAY-598 R-isomer; BAY 598 R-isomer; BAY598 R-isomer. CAS No. 1906920-28-2. Molecular formula: C22H20Cl2F2N6O3. Mole weight: 525.33. | |
BAY 60-2770 Quick inquiry Where to buy Suppliers range | ≥98% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 1027642-43-8. Pack Sizes: 5MG, 25MG. Mole weight: 623.63. Catalog: AP1027642438. Assay: ≥98% (HPLC). | |
BAY-6035 Quick inquiry Where to buy Suppliers range | BAY-6035 is an inhibitor of SET and MYND domain-containing protein 3 (SMYD3) with IC50 of 70 nMm, which exhibits >100-fold selectivity for SMYD3 over other histone methyltransferases. BAY-6035 inhibits methylation of MEKK2 peptide in a cell-free assay and in cell. Synonyms: (2S)-1-(3-azabicyclo[3.1.0]hex-3-ylcarbonyl)-N-(2-cyclopropylethyl)-2,3,4,5-tetrahydro-2-methyl-4-oxo-1H-1,5-benzodiazepine-7-carboxamide. Grades: ≥95%. CAS No. 2247890-13-5. Molecular formula: C22H28N4O3. Mole weight: 396.48. | |
BAY 60-6583 Quick inquiry Where to buy Suppliers range | BAY 60-6583 is a potent and selective adenosine A2B receptor agonist. BAY 60-6583 shows protective effects against ischemia in both the heart and kidney in animal models. BAY 60-6583 is also a useful therapeutic drug in the treatment of acute lung injury. Group: Biochemicals. Alternative Names: 2- [ [6-Amino-3, 5-dicyano-4- [4- (cyclopropylmethoxy) phenyl] -2-pyridinyl] thio] acetamide; BR 4887. Grades: Highly Purified. CAS No. 910487-58-0. Pack Sizes: 10mg, 25mg. Molecular Formula: C19H17N5O2S. US Biological Life Sciences. | Worldwide |
BAY 60-6583 Quick inquiry Where to buy Suppliers range | BAY 60-6583 is a potent and selective adenosine A2B receptor agonist (EC50 = 2.83 nM for murine A2B receptor) displaying selectivity for A2B over A1, A2A and A3 receptors. BAY 60-6583 decreases fMLP-induced superoxide production in neutrophils at low concentrations (1-10 nM) and attenuates infarct size in a mouse model of myocardial ischemia, suggesting that it may be beneficial for the treatment of disorders in the coronary arteries, atherosclerosis and ischemia-reperfusion injury. Synonyms: BAY 60-6583; BAY-60-6583; BAY60-6583. 2-[[6-Amino-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]-2-pyridinyl]thio]-acetamide; BR 4887. Grades: ≥98% by HPLC. CAS No. 910487-58-0. Molecular formula: C19H17N5O2S. Mole weight: 379.44. | |
BAY 60-6583-13C2,15N Quick inquiry Where to buy Suppliers range | BAY 60-6583-13C2,15N. Group: Biochemicals. Alternative Names: 2- [ [6-Amino-3, 5-dicyano-4- [4- (cyclopropylmethoxy) phenyl] -2-pyridinyl] thio] acetamide-13C2, 15N; BR 4887-13C2,15N. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C1713C2H17N415NO2S, Molecular Weight: 382.41. US Biological Life Sciences. | Worldwide |
Bay 60-7550 Quick inquiry Where to buy Suppliers range | Bay 60-7550 is a potent PDE2 inhibitor. It is 50-fold more selective for PDE2 compared to PDE1 and greater than 100-fold selective compared to PDE5 PDE3B, PDE4B, PDE7B, PDE8A, PDE9A, PDE10A, and PDE11A. Synonyms: BAY60-7550; BAY 60-7550; BAY-60-7550; BAY-607550; BAY 607550; BAY607550. Grades: >98%. CAS No. 439083-90-6. Molecular formula: C27H32N4O4. Mole weight: 476.57. | |
BAY 60-7550 Quick inquiry Where to buy Suppliers range | The compound induced anxiety by inhibition of. Group: Biochemicals. Alternative Names: 2-[ (3, 4-Dimethoxyphenyl) methyl]-7-[ (1R) -1-[ (1R) -1-hydroxyethyl]-4-phenylbutyl]-5-methyl-imidazo[5, 1-f][1, 2, 4]triazin-4 (1H) -one. Grades: Highly Purified. CAS No. 439083-90-6. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
BAY 60-7550 Quick inquiry Where to buy Suppliers range | ≥95% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 439083-90-6. Pack Sizes: 5MG, 25MG. Mole weight: 476.57. Catalog: AP439083906. Assay: ≥95% (HPLC). | |
BAY 61-3606 Quick inquiry Where to buy Suppliers range | BAY 61-3606 is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity with no inhibitory effect against Btk, Fyn, Itk, Lyn, and Src. Synonyms: BAY 61-3606; BAY 613606; BAY 61 3606; BAY-61-3606; BAY613606; BAY61 3606. Grades: >98%. CAS No. 732983-37-8. Molecular formula: C20H18N6O3. Mole weight: 390.4. | |
BAY 61-3606 dihydrochloride Quick inquiry Where to buy Suppliers range | BAY 61-3606 is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity with no inhibitory effect against Btk, Fyn, Itk, Lyn, and Src. Synonyms: BAY 61-3606 dihydrochloride; BAY-61-3606 dihydrochloride; BAY61-3606 dihydrochloride. Grades: >98%. CAS No. 648903-57-5. Molecular formula: C20H18N6O3.2HCl. Mole weight: 463.32. | |
BAY 61-3606 hydrochloride Quick inquiry Where to buy Suppliers range | BAY 61-3606 is a cell-permeable, reversible inhibitor of spleen tyrosine kinase (Syk; Ki=7.5 nM; IC50=10 nM). It is 700 to >1,000-fold more selective for Syk over Src, Lyn, Fyn, Itk, and Btk. BAY 61-3606 can inhibit degranulation (IC50 = 5-46 nM) and block cytokine release from mast cells. It shows good in vivo efficacy in the treatment of various allergy and asthma conditions in rat models. This compound has been used in a pre-clinical model to explore the feasibility of targeting Syk in the treatment of retinoblastoma. Synonyms: 2-[[7-(3,4-dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino]-3-pyridinecarboxamide monohydrochloride; BAY 61-3606 HCl. Grades: ≥98%. CAS No. 1615197-10-8. Molecular formula: C20H18N6O3·HCl. Mole weight: 426.9. | |
Bay 61-3606 Hydrochloride (2-[[7- (3, 4-Dimethoxyphenyl) imidazo[1, 2-c]pyrimidin-5-yl]amino]pyridine-3-carboxamide, HCl) Quick inquiry Where to buy Suppliers range | Cell-permeable. A potent, ATP-competitive and reversible inhibitor of spleen tyrosine kinase (Syk) (IC50 = 10nM). Displays excellent selectivity against many other kinases including Btk, Fyn, Itk, Lyn and Src up to concentrations of 4.7uM. Shows good in vivo efficacy in the treatment of various allergy and asthma conditions in rat models. Group: Biochemicals. Alternative Names: 2-[[7- (3, 4-Dimethoxyphenyl) imidazo[1, 2-c]pyrimidin-5-yl]amino]pyridine-3-carboxamide, HCl. Grades: Highly Purified. CAS No. 732938-37-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
BAY 61-3606 hydrochloride hydrate Quick inquiry Where to buy Suppliers range | ≥98% (HPLC), powder. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. Pack Sizes: 5MG, 25MG. Mole weight: 390.40 (anhydrous free base basis). Catalog: IAR4241481. Assay: ≥98% (HPLC). | |
Bay 65-1942 free base Quick inquiry Where to buy Suppliers range | Bay 65-1942 is an ATP-competitive inhibitor that selectively targets IKKβ kinase. Synonyms: BAY 65-1942; BAY-65-1942; BAY65-1942; BAY 651942; BAY-651942; BAY651942. BAY65-1942 free base. Grades: >98%. CAS No. 600734-02-9. Molecular formula: C22H25N3O4. Mole weight: 395.45. | |
Bay 65-1942 hydrochloride Quick inquiry Where to buy Suppliers range | Bay 65-1942 hydrochloride is an ATP-competitive inhibitor that selectively targets IKKβ kinase. Synonyms: KINK-1; KINK 1; KINK1; Bay65-1942 Hydrochloride; Bay651942 Hydrochloride; Bay65-1942 HCl; Bay651942 HCl. Grades: >98%. CAS No. 600734-06-3. Molecular formula: C22H26ClN3O4. Mole weight: 431.91. | |
Bay 65-1942 R form Quick inquiry Where to buy Suppliers range | Bay 65-1942 R form is an ATP-competitive inhibitor that selectively targets IKKβ kinase. Synonyms: Bay 65-1942. Grades: >98%. CAS No. 758683-21-5. Molecular formula: C22H25N3O4. Mole weight: 395.45. | |
BAY-671 Quick inquiry Where to buy Suppliers range | BAY-671 is developed from the structure of BRD4 inhibitor used for the treatment of solid tumor. Studies in vtro and in vivo indicated that it has inhibitory effect on multiple cancer types. Uses: The treatment of solid tumor. Synonyms: BAY 671; BAY671. | |
BAY 677 Quick inquiry Where to buy Suppliers range | BAY 677 is an inactive control for BAY 678 and a human neutrophil elastase (HNE) inhibitor. Synonyms: BAY-677; BAY 677; BAY677; 5-[(4S)-5-Acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-2-pyridinecarbonitrile. Grades: ≥98% by HPLC. CAS No. 2117404-84-7. Molecular formula: C20H15F3N4O2. Mole weight: 400.35. | |
BAY 678 Quick inquiry Where to buy Suppliers range | BAY 678 is a cell-permeable human neutrophil elastase (HNE) inhibitor (IC50 = 20 nM) that displays around 2000-fold selectivity for NHE over a panel of 21 other serine proteases. Synonyms: BAY 678; BAY678; BAY-678; 5-[(4R)-5-Acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-2-pyridinecarbonitrile. Grades: ≥98% by HPLC. CAS No. 675103-36-3. Molecular formula: C20H15F3N4O2. Mole weight: 400.35. | |
BAY-678 Quick inquiry Where to buy Suppliers range | ≥98% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 675103-36-3. Pack Sizes: 5MG, 25MG. Mole weight: 400.35. Catalog: AP675103363. Assay: ≥98% (HPLC). | |
BAY-721973 Quick inquiry Where to buy Suppliers range | BAY-721973 is a bio-active chemical,but few detailed information has been published yet. Synonyms: BAY-721973; BAY 721973; BAY721973; Sorafenib metabolite M3; UNII-83F1Z938Q0; 4- (4- ( ( ( (4-chloro-3- (trifluoromethyl) phenyl) amino) carbonyl) amino) phenoxy) -N- (hydroxymethyl) -2-Pyridinecarboxamide. Grades: 98%. CAS No. 1380310-94-0. Molecular formula: C21H16ClF3N4O4. Mole weight: 480.83. | |
BAY 73-4506 Quick inquiry Where to buy Suppliers range | BAY 73-4506 Inhibitor. Uses: Scientific use. Product Category: T1792. CAS No. 755037-03-7. | |
BAY 73-6691 Quick inquiry Where to buy Suppliers range | BAY 73-6691 is a phosphodiesterase inhibitor selective for the PDE9A subtype under the development of Bayer. It selectively inhibits human PDE9 with IC50 value of 55 nM in vitro.BAY 73-6691 was developed for the treatment of Alzheimer's disease, but pre-clinical research is at an early stage. Uses: Alzheimer's disease. Synonyms: BAY-73-6691; BAY736691; BAY73-6691; UNII-80ZTV3INTW; (R)-Bay-73-6691; 1-(2-Chlorophenyl)-6-[(2R)-3,3,3-trifluoro-2-methylpropyl]-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidine-4-one. Grades: 98%. CAS No. 794568-92-6. Molecular formula: C15H12ClF3N4O. Mole weight: 356.73. | |
BAY-754 Quick inquiry Where to buy Suppliers range | BAY-754 is an ALK-1 inhibitor used as an anti-angiogenesis agent. It inhibited the eye vascular leakage in dose manner in mouse model. Uses: The treatment of eye disorders. Synonyms: BAY-754; BAY 754; BAY-54. | |
BAY-8002 Quick inquiry Where to buy Suppliers range | BAY-8002 is a novel potent, selective, orally available monocarboxylate transporter 1 (MCT1) inhibitor (Kd=7.9 nM), which inhibits cellular lactate uptake in DLD-1 cells with IC50 of 85 nM. BAY-8002 significantly increases intratumor lactate levels and transiently modulated pyruvate levels. Synonyms: BAY 8002BAY-8002; BAY 8002; BAY8002; 2-(2-chloro-5-(phenylsulfonyl)benzamido)benzoic acid. Grades: ≥98%. CAS No. 724440-27-1. Molecular formula: C20H14ClNO5S. Mole weight: 415.85. | |
BAY8040 Quick inquiry Where to buy Suppliers range | This active molecular is a Selective Human Neutrophil Elastase Inhibitor and combines excellent potency and selectivity with a promising pharmacokinetic profile. In animal models for pulmonary arterial hypertension, BAY8040 shows the efficancy of decreasing cardiac remodeling and amelioration of cardiac function in vivo. Uses: Cardiac remodeling and amelioration of cardiac function. Synonyms: BAY8040; BAY-8040; BAY 8040; (R)-4-(7-methyl-2,5-dioxo-1-(3-(trifluoromethyl)phenyl)-1,2,3,4,5,6,7,8-octahydropyrimido[4,5-d]pyridazin-4-yl)benzonitrile. Grades: 98%. CAS No. 1194453-23-0. Molecular formula: C21H16F3N5O2. Mole weight: 427.39. | |
BAY 826 Quick inquiry Where to buy Suppliers range | BAY-826 is a selective and potent TIE-2 inhibitor with Kd of 1.6 nM and IC50 of 1.3 nM for autophosphorylation. BAY-826 is highly selective against other angiogenic kinases, such as VEGFR, FGFR, or PDGFR, and affects VEGF-stimulated proliferation of HUVEC. It displays in vivo efficacy in some murine glioma models. Synonyms: [3-Cyano-5- [ [ [2, 4-dimethyl-5- [6- (3-pyridinyl) -1H-imidazo [1, 2-b] pyrazol-1-yl] phenyl] amino] carbonyl] phenyl] pentafluorosulfur. Grades: ≥98% by HPLC. CAS No. 1448316-08-2. Molecular formula: C26H19F5N6OS. Mole weight: 558.53. | |
BAY-850 Quick inquiry Where to buy Suppliers range | BAY-850 is a potent isotype-selective ATPase family AAA domain protein 2 (ATAD2) inhibitor with IC50 of 166 nM and can be used as a probe. Grades: 98%. CAS No. 2099142-76-2. Molecular formula: C38H44ClN5O3. Mole weight: 654.2. | |
BAY 85-8501 Quick inquiry Where to buy Suppliers range | This active molecular is a highly selective neutrophil elastase inhibitor.IC50 for HNE is 0.065 nM, LipE is 7.2. BAY 85-8501 was being tested in clinical studies for the treatment of pulmonary diseases. In Feb 2013, Phase-II clinical trials in Bronchiectasis in Spain were on going. In Mar 2013, Phase-II clinical trials in Bronchiectasis in France, Germany and Italy were on going. In Jun 2014, Bayer completed a phase IIa trial in Bronchiectasis in United Kingdom, Spain, France, Germany and Italy. Uses: The treatment of pulmonary diseases. Synonyms: BAY 85-8501; BAY85-8501; BAY-85-8501; BAY 858501; BAY858501; BAY-858501. (S)-4-(4-cyano-2-(methylsulfonyl)phenyl)-3,6-dimethyl-2-oxo-1-(3-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydropyrimidine-5-carbonitrile. Grades: 98%. CAS No. 1161921-82-9. Molecular formula: C22H17F3N4O3S. Mole weight: 474.46. | |
BAY 87-2243 Quick inquiry Where to buy Suppliers range | BAY 87-2243 inhibits HIF-1 reporter gene activity and CA9 protein expression with IC50 of 0.7 nM and 2 nM, respectively. Synonyms: BAY 872243; BAY872243; BAY-872243; BAY 87-2243; BAY87-2243; BAY-87-2243. Grades: >98%. CAS No. 1227158-85-1. Molecular formula: C26H26F3N7O2. Mole weight: 525.53. | |
BAY 87-2243 Quick inquiry Where to buy Suppliers range | BAY 87-2243, 1227158-85-1, BAY87-2243, bay-87-2243, 5XQ7LE6DZG, 1-cyclopropyl-4-[4-[[5-methyl-3-[3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl]-1H-pyrazol-1-yl]methyl]-2-pyridinyl]-piperazine, BAY-872243, 5-(1-((2-(4-Cyclopropylpiperazin-1-yl)pyridin-4-yl)methyl)-5-methyl-1H-pyrazol-3-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole, 5-[1-[[2-(4-cyclopropylpiperazin-1-yl)pyridin-4-yl]methyl]-5-methylpyrazol-3-yl]-3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazole, 1-Cyclopropyl-4-(4-((5-methyl-3-(3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)-1H-pyrazol-1-yl)methyl)-2-pyridinyl)piperazine, Piperazine, 1-cyclopropyl-4-(4-((5-methyl-3-(3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)-1H-pyrazol-1-yl)methyl)-2-pyridinyl)-, 1-Cyclopropyl-4-[4-[[5-methyl-3-[3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl]-1H-pyrazol-1-yl]methyl]-2-pyridinyl]piperazine, UNII-5XQ7LE6DZG, SCHEMBL2359661, CHEMBL4303384, DTXSID901025725, BCP09519, EX-A2031, BAY872243, NSC781016, NSC795507, s7309, AKOS026750511, BAY 872243, CCG-269886, NSC-781016, NSC-795507, NCGC00378636-03, AC-33661, BS-15014, HY-15836, C71860, BAY 872243; BAY872243; BAY-872243, 1-Cyclopropyl-4-{4-[(5-methyl-3-{3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl}-1H-pyrazol-1-yl)methyl]pyridin-2-yl}piperazine. | |
BAY-876 Quick inquiry Where to buy Suppliers range | BAY-876 Inhibitor. Uses: Scientific use. Product Category: T3713. CAS No. 1799753-84-6. | |
BAY-876 Quick inquiry Where to buy Suppliers range | BAY-876 is a potent and selective inhibitor of GLUT1, which is overexpressed in multiple cancers. Uses: Anticancer agent. Synonyms: BAY-876; BAY 876; BAY876. 4-N-[1-[(4-cyanophenyl)methyl]-5-methyl-3-(trifluoromethyl)pyrazol-4-yl]-7-fluoroquinoline-2,4-dicarboxamide. Grades: 95%. CAS No. 1799753-84-6. Molecular formula: C24H16F4N6O2. Mole weight: 496.426. | |
BAY-985 Quick inquiry Where to buy Suppliers range | BAY-985 is a highly effective, orally active and selective TANK-binding kinase 1 (TBK1) and IκB kinase ε dual inhibitor, with anti-tumor activity. Synonyms: BAY985; GTPL10597; EX-A3294. Grades: ≥98% by HPLC. CAS No. 2409479-29-2. Molecular formula: C27H30F3N9O. Mole weight: 553.6. | |
Bayberry Myrica Rubra Fruit P.E. 80% Myricetin HPLC Quick inquiry Where to buy Suppliers range | Bayberry Myrica Rubra Fruit P.E. 80% Myricetin HPLC. | CA, FL & NJ |
BayCysLT2 Quick inquiry Where to buy Suppliers range | BayCysLT2 is a potent and selective antagonist for the CysLT2R, which attenuates exacerbation of infarction damage to the myocardium caused by endothelial CysLT2R overexpression. CysLT2R can influence myocardial damage post-ischemia/reperfusion by mediating leukocyte adhesion and infiltration. CysLT2R can further blockade post-infarction maintains its protective properties, indicating a possible therapeutic role for CysLT2R antagonism. BayCysLT2 inhibits radioligand binding of LTD4 to CysLT2 and CysLT1 receptor cell lines with IC50 values of 35 and >10,000 nM, respectively. Synonyms: CAY10633; 3-[[(3-carboxycyclohexyl)amino]carbonyl]-4-[3-[4-(4-phenoxybutoxy)phenyl]propoxy]-benzoic acid. Grades: ≥95%. CAS No. 712313-33-2. Molecular formula: C34H39NO8. Mole weight: 589.7. | |
Bayer9017 Quick inquiry Where to buy Suppliers range | Bayer9017 is a bio-active chemical compound. Synonyms: Bayer 9017; Bayer-9017; 3,5-Xylenol, 4-(methylthio)-, O-ester with O,O-diethyl phosphorothioate; Phosphorothioic acid, O-(3,5-dimethyl-4-(methylthio)phenyl) O,O-diethyl ester; BAY 9017. Grades: 98%. CAS No. 52-60-8. Molecular formula: C13H21O3PS2. Mole weight: 320.43. | |
Bayogenin Quick inquiry Where to buy Suppliers range | Bayogenin. Group: Biochemicals. Grades: Plant Grade. CAS No. 6989-24-8. Pack Sizes: 10mg. Molecular Formula: C30H48O5, Molecular Weight: 488.7. US Biological Life Sciences. | Worldwide |
Bayogenin Quick inquiry Where to buy Suppliers range | Bayogenin. Group: Biobased Products. Alternative Names: (2β,3β,4α)-2,3,23-Trihydroxy-olean-12-en-28-oic acid. Grades: 98%. CAS No. 6989-24-8. Product ID: BBC6989248. Molecular formula: C30H48O5. Mole weight: 488.7. IUPAC Name: (4aS, 6aR, 6aS, 6bR, 8aR, 9R, 10R, 11S, 12aR, 14bS)-10, 11-dihydroxy-9-(hydroxymethyl)-2, 2, 6a, 6b, 9, 12a-hexamethyl-1, 3, 4, 5, 6, 6a, 7, 8, 8a, 10, 11, 12, 13, 14b-tetradecahydropicene-4a-carboxylic acid. Appearance: Powder. Density: 1.19±0.1 g/ml. SMILES: C[C@@]12CC[C@@H]3[C@@] ([C@H]1CC=C4[C@]2 (CC[C@@]5 ([C@H]4CC (CC5) (C)C)C (=O)O)C) (C[C@@H] ([C@@H] ([C@@]3 (C)CO)O)O)C. | |
Bayogenin 3-O- β-D-glucopyranoside Quick inquiry Where to buy Suppliers range | Bayogenin 3-O- β-D-glucopyranoside. Group: Biochemicals. CAS No. 104513-86-2. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
Bayogenin 3-O-β-D-glucopyranoside Quick inquiry Where to buy Suppliers range | Bayogenin 3-O-β-D-glucopyranoside is a triterpenoid saponin isolated from the aerial parts of Polygala japonica Houtt. Synonyms: 2beta,23-Dihydroxy-3beta-(beta-D-glucopyranosyloxy)oleana-12-ene-28-oic acid. Grades: >98%. CAS No. 104513-86-2. Molecular formula: C36H58O10. Mole weight: 650.85. | |
Bay Oil Natural Quick inquiry Where to buy Suppliers range | Bay Oil Natural. CAS No. MIXTURE. Kosher: Y. VIGON Item # 508413. Categories: Speciality Ingredients Suppliers, Flavors, Fragrances, Perfumers, Cosmetics, Aromatherapy, Essential Oils. | America & Internationally |
Bay Oil Terpeneless Quick inquiry Where to buy Suppliers range | Bay Oil Terpeneless. CAS No. 68916-05-2. Kosher: Y. VIGON Item # 501494. Categories: Speciality Ingredients Suppliers, Flavors, Fragrances, Perfumers, Cosmetics. | America & Internationally |
BAY R3401 Quick inquiry Where to buy Suppliers range | ≥98% (HPLC), solid. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 100276-03-7. Pack Sizes: 5MG, 25MG. Mole weight: 375.85. Catalog: AP100276037. Assay: ≥98% (HPLC). | |
BAY-u 3405 Quick inquiry Where to buy Suppliers range | BAY-u 3405. Group: Biochemicals. Grades: Purified. CAS No. 116649-85-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
BAY U6751 hydrate Quick inquiry Where to buy Suppliers range | solid, ≥98% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 114290-51-6 (anhydrous). Pack Sizes: 5MG, 25MG. Mole weight: 451.81 (anhydrous basis). Catalog: ALP114290516. Assay: ≥98% (HPLC). | |
BAY-u 9773 Quick inquiry Where to buy Suppliers range | BAY-u 9773 is a non-selective cysteinyl leukotriene receptor antagonist displaying equal affinity for both CysLT1 and CysLT2 receptors (pKB = 6.8 and 6.5, respectively). BAY-u 9773 was investigated to inhibit bronchial and venous muscle contractions in human muscle preparations. BAY-u 9773 also acts as a competitive antagonist of LTC4- and LTE4-induced contractions of the guinea pig trachea. Synonyms: BAYu9773; BAY-u9773; BAY u9773. 4-[[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-Carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]thio]benzoic acid; 6(R)-(4-Carboxyphenylthio)-5(S)-hydroxy-7(E),9(E),11(E),14(Z)-eicosatetraenoic acid. CAS No. 154978-38-8. Molecular formula: C27H36O5S. Mole weight: 472.64. | |
BAY-u 9773 Quick inquiry Where to buy Suppliers range | BAY-u 9773. Group: Biochemicals. Grades: Purified. CAS No. 154978-38-8. Pack Sizes: 50ug. US Biological Life Sciences. | Worldwide |
BAY-X 1005 Quick inquiry Where to buy Suppliers range | BAY-X 1005. Group: Biochemicals. Grades: Purified. CAS No. 128253-31-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
BAY-X-1005 Quick inquiry Where to buy Suppliers range | BAY-X 1005 is a potent and selective FLAP (5-lipoxygenase-activating protein) inhibitor. BAY-X 1005 is also a selective inhibitor of leukotriene synthesis. BAY-X1005 inhibited LTB4 synthesis with IC50 values of 220 nM for isolated PMNL of human and inhibited LTC4 synthesis with IC50 value of 210 nM in mouse macrophages. Phase-III for Myocardial infarction in USA was suspended in 2006. Uses: Myocardial infarction. Synonyms: BAY-X-1005; BAY X 1005; BAYX1005; Veliflapon;DG-031; DG 031; DG031; (2R)-2-cyclopentyl-2-[4-(quinolin-2-ylmethoxy)phenyl]acetic acid. Grades: >98 %. CAS No. 128253-31-6. Molecular formula: C23H23NO3. Mole weight: 361.43. | |
BAY-Y 3118 Quick inquiry Where to buy Suppliers range | BAY-Y 3118 is a 4-quinolone with outstanding antimicrobial activity against Gramnegative and Gram-positive pathogens as well as anaerobic and intracellular bacteria and might be an important contribution to progress in anti-infective therapy. Synonyms: 7-[(4aS,7aS)-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridin-6-yl]-8-chloro-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylic acid; 1-cyclopropyl-7-(2,8-diazabicyclo(4.3.0)non-8-yl)-6-fluoro-8-chloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid hydrochloride; Bay y 3118; Bay Y3118; Bay-Y3118. CAS No. 151213-16-0. Molecular formula: C20H21ClFN3O3. Mole weight: 405.85. | |
BAZ2-ICR Quick inquiry Where to buy Suppliers range | BAZ2-ICR is a bromodomain inhibitor with IC50 of 130 nM for BAZ2A and IC50 of 180 nM for BAZ2B. It demonstrates 15-fold selectivity for binding BAZ2A/B over CECR2 and >100-fold selectivity over all other bromodomains. Synonyms: 4-(4-(1-methyl-1H-pyrazol-4-yl)-1-(2-(1-methyl-1H-pyrazol-4-yl)ethyl)-1H-imidazol-5-yl)benzonitrile; BAZ2ICR. Grades: ≥98%. CAS No. 1665195-94-7. Molecular formula: C20H19N7. Mole weight: 357.41. | |
Bazedoxifene-4'-Glucuronide Quick inquiry Where to buy Suppliers range | Bazedoxifene-4'-Glucuronide is a metabolite of Bazedoxifene. Synonyms: Bazedoxifene 4'-β-D-Glucuronide; [1-[[4-[2-(Hexahydro-1H-azepin-1-yl)ethoxy]phenyl]Methyl]-5-hydroxy-3-Methyl-1H-indol-2-yl]phenyl β-D-Glucopyranosiduronic Acid. Grades: > 95%. CAS No. 328933-64-8. Molecular formula: C36H42N2O9. Mole weight: 646.74. | |
Bazedoxifene-5-Glucuronide Quick inquiry Where to buy Suppliers range | Bazedoxifene-5-Glucuronide is a metabolite of Bazedoxifene. Synonyms: Bazedoxifene 5-β-D-Glucuronide; 1-[[4-[2-(Hexahydro-1H-azepin-1-yl)ethoxy]phenyl]Methyl]-2-(4-hydroxyphenyl)-3-Methyl-1H-indol-5-yl β-D-Glucopyranosiduronic Acid. Grades: > 95%. CAS No. 328933-56-8. Molecular formula: C36H42N2O9. Mole weight: 646.74. | |
Bazedoxifene acetate Quick inquiry Where to buy Suppliers range | Bazedoxifene acetate, also called as TSE424 or WAY-140424, is a selective nonsteroidal estrogen receptor modulator (SERM) with antiosteoporotic activity (ERα: IC50= 26 nM; ERβ= 99 nM). Uses: Bone density conservation agents. Synonyms: TSE 424; TSE-424; TSE424; WAY-140424; WAY 140424; WAY140424. Grades: 95%. CAS No. 198481-33-3. Molecular formula: C32H38N2O5. Mole weight: 530.66. | |
Bazedoxifene Acetate Quick inquiry Where to buy Suppliers range | Bazedoxifene Acetate is a nonsteroidal selective estrogen receptor modulator (SERM). Bazedoxifene Acetate is used as an antiosteoporotic. Group: Biochemicals. Alternative Names: 1-[[4-[2- (Hexahydro-1H-azepin-1-yl) ethoxy]phenyl]methyl]-2- (4-hydroxyphenyl) -3-methyl-. Grades: Highly Purified. CAS No. 198481-33-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Bazedoxifene HCl Quick inquiry Where to buy Suppliers range | Cas No. 198480-56-7. |