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| Product | Description | |
|---|---|---|
| Bay 55-9837 | Bay 55-9837 is a selective VPAC2 receptor agonist (EC50 = 0.4, 100 and >1000 nM for VPAC2, VPAC1 and PAC1, respectively in a cAMP accumulation assay; IC50=60, 8700 and >10000 nM for VPAC2, VPAC1 and PAC1, respectively in a competition binding assay). It promotes glucose-dependent insulin secretion in isolated human pancreatic islets and inhibits HIV-1 viral replication. CAS No. 463930-25-8. Molecular formula: C167H270N52O46. Mole weight: 3742.29. |  |
| BAY 56-3722 | BAY 56-3722 is a water-soluble camptothecin derivative conjugated to a carbohydrate moiety exhibiting antineoplastic activity. BAY 56-3722 stabilizes the topoisomerase I-DNA covalent complex and forms an enzyme-drug-DNA ternary complex. The peptide carbohydrate moiety of this agent stabilizes the lactone form of camptothecin in blood. Synonyms: BAY-563722; BAY56 3722; BAY 38-3441; BAY 38 344; (S)-4-ethyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl ((4-(((2R,3S,4R,5R,6S)-3,5-dihydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)phenyl)carbamothioyl)-L-histidyl-L-valinate. CAS No. 215604-75-4. Molecular formula: C45H50ClN7O11S. Mole weight: 895.98. | |
| BAY 56-3722 hydrochloride | BAY 56-3722, a water-soluble camptothecin derivative, is a DNA-Intercalating drug that stabilizes the topoisomerase I-DNA covalent complex and forms an enzyme-drug-DNA ternary complex. Synonyms: BAY 56-3722; BAY56-3722; BAY-56-3722; N-[4- (6-Deoxy-3-O-methyl-beta-L-galactopyranosyloxy) phenylaminothiocarbonyl]-L-histidyl-L-valine 4(S)-ethyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl ester hydrochloride; N-[4-(3-O-Methyl-beta-L-fucopyranosyloxy)p; Afeletecan hydrochloride; BAY 38-3441; L-Valine, N- ( ( (4- ( (6-deoxy-3-O-methyl-beta-L-galactopyranosyl) oxy) phenyl) amino) thioxomethyl) -L-histidyl-, (4S)-4-ethyl-3,4,12,14-tetrahydro-3,14-dioxo-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinolin-4-yl ester, hydrochloride (1:1); 215604-75-4 (BAY 56-3722 free base); 215604-74-3 (BAY 56-3722 HCl salt; 215604-66-3 (diastereomeric mixture). Grades: >98%. CAS No. 215604-74-3. Molecular formula: C45H49N7O11S.HCl. Mole weight: 932.447. | |
| BAY-57-1293 | BAY 57-1293 represents a new class of potent inhibitors of herpes simplex virus (HSV) that target the virus helicase primase complex. Potent helicase-primase inhibitor (HPI) effective against herpes simplex virus (HSV) infections with IC50 value of 20 nM for inhibition of the replication of both HSV-1 and HSV-2 in Vero cells, and ED50 value of 0.5 mg/kg for both HSV-1 and HSV-2 in the murine lethal challenge model of disseminated herpes. Uses: For research used only. Synonyms: Pritelivir; BAY-57-1293; BAY 57-1293; BAY-57 1293; BAY 57 1293; BAY571293; AIC316; AIC 316; AIC-316. Grades: 98%. CAS No. 348086-71-5. Molecular formula: C18H18N4O3S2. Mole weight: 402.49. | |
| BAY 58-2667 hydrochloride | BAY 58-2667, also known as Cinaciguat, is a potent nitric oxide (NO)-independent soluble guanylyl cyclase (sGC) activator (EC50 = 6.4 nM). It exhibits antihypertensive effects in vivo and is used in the treatment of acute decompensated heart failure (ADHF). Synonyms: 5-Fluoro-2-methoxy-[1-[2-[(methylsulfonyl)amino]ethyl]-4-piperidinyl]-1H-indole-3-methylcarboxylate Sulfamate; Cinaciguat HCl; BAY 582667 HCl; BAY-582667 HCl; BAY582667 HCl; BAY 58-2667 HCl; BAY-58-2667 HCl; BAY58-2667 HCl; Cinaciguat HCl. Grades: ≥98% by HPLC. CAS No. 646995-35-9. Molecular formula: C36H39NO5.HCl. Mole weight: 602.16. | |
| BAY 58-2667 hydrochloride | Nitric oxide (NO)- and heme-independent soluble guanylyl cyclase activator. Shows potent cardiovascular effects. Improves cardiopulmonary hemodynamics in patients with acute decompensated heart failure. Exhibits potent vasodilator and antiplatelet activity. Anti-aggregating agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 1240669-95-7. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| BAY-588 | BAY-588 is a glucose transporter inhibitor and derivative of BAY-876. BAY-876 is a potent, highly selective, cell-permeable inhibitor of glucose transporter GLUT1. It selectively inhibits glucose transporter 4 (Glut4), Glut1, and Glut3 over Glut2 with IC50 values of 0.5, 1.18, 5.47, and >10 μM, respectively, in CHO cells expressing human recombinant transporters. Synonyms: BAY 588; BAY588; N4-[1-[[4-(1,1-Dimethylethyl)phenyl]methyl]-5-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-7-fluoro-2,4-quinolinedicarboxamide. Grades: ≥98%. CAS No. 1799759-24-2. Molecular formula: C27H25F4N5O2. Mole weight: 527.5. | |
| BAY 59-3074 | Bay 59-3074 is a novel, selective CB1/CB2 receptor partial agonist(Ki values are 48.3 and 45.5 nM at human CB1 and CB2 receptors respectively). Uses: Novel cb1/cb2 receptor partial agonist. Synonyms: BAY-59-3074; BAY 59-3074; BAY59-30743-[2-Cyano-3-(trifluoromethyl)phenoxy]phenyl 4,4,4-trifluoro-1-butanesulfonic acid ester. Grades: ≥98%. CAS No. 406205-74-1. Molecular formula: C18H13F6NO4S. Mole weight: 453.358. | |
| BAY-598 | BAY-598 is a potent, peptide-competitive chemical probe for SET and MYND domain-containing protein 2 (SMYD2), IC50 values of 27 nM and 58 nM for biochemical and cellular activity, respectively. BAY 598 exhibits 100-fold selectivity for SMYD2 over other histone methyltransferases and non-epigenetic enzymes. Synonyms: (S, E) -N- (1- (N'-cyano-N- (3- (difluoromethoxy) phenyl) carbamimidoyl) -3- (3, 4-dichlorophenyl) -4, 5-dihydro-1H-pyrazol-4-yl) -N-ethyl-2-hydroxyacetamide; BAY-598; BAY 598; BAY598. CAS No. 1906919-67-2. Molecular formula: C22H20Cl2F2N6O3. Mole weight: 525.33. | |
| BAY-598 R-isomer | BAY-598 R-isomer is the R-isomer of BAY589 which is a potent, peptide-competitive chemical probe for SET and MYND domain-containing protein 2 (SMYD2), IC50 values of 27 nM and 58 nM for biochemical and cellular activity, respectively. BAY 598 exhibits 100-fold selectivity for SMYD2 over other histone methyltransferases and non-epigenetic enzymes. Synonyms: (R, E) -N- (1- (N'-cyano-N- (3- (difluoromethoxy) phenyl) carbamimidoyl) -3- (3, 4-dichlorophenyl) -4, 5-dihydro-1H-pyrazol-4-yl) -N-ethyl-2-hydroxyacetamide; BAY-598 R-isomer; BAY 598 R-isomer; BAY598 R-isomer. CAS No. 1906920-28-2. Molecular formula: C22H20Cl2F2N6O3. Mole weight: 525.33. | |
| BAY-6035 | BAY-6035 is an inhibitor of SET and MYND domain-containing protein 3 (SMYD3) with IC50 of 70 nMm, which exhibits >100-fold selectivity for SMYD3 over other histone methyltransferases. BAY-6035 inhibits methylation of MEKK2 peptide in a cell-free assay and in cell. Synonyms: (2S)-1-(3-azabicyclo[3.1.0]hex-3-ylcarbonyl)-N-(2-cyclopropylethyl)-2,3,4,5-tetrahydro-2-methyl-4-oxo-1H-1,5-benzodiazepine-7-carboxamide. Grades: ≥95%. CAS No. 2247890-13-5. Molecular formula: C22H28N4O3. Mole weight: 396.48. | |
| BAY-6035 | BAY-6035 is a potent, selective and substrate-competitive inhibitor of SMYD3. BAY-6035 inhibits methylation of MEKK2 peptide with an IC 50 of 88 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2247890-13-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112080. |  |
| BAY 60-6583 | BAY 60-6583 is a potent and high-affinity agonist of adenosine A 2B receptor ( EC 50 = 3 nM) over A1, A2A, and A3 receptors. BAY 60-6583 binds to mouse, rabbit, and dog A2BAR with K i values of 750 nM, 340 nM and 330 nM, respectively. BAY 60-6583 has a cardioprotective effect in a myocardial ischemia model [1] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 910487-58-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103171. | |
| BAY 60-6583 | BAY 60-6583 is a potent and selective adenosine A2B receptor agonist (EC50 = 2.83 nM for murine A2B receptor) displaying selectivity for A2B over A1, A2A and A3 receptors. BAY 60-6583 decreases fMLP-induced superoxide production in neutrophils at low concentrations (1-10 nM) and attenuates infarct size in a mouse model of myocardial ischemia, suggesting that it may be beneficial for the treatment of disorders in the coronary arteries, atherosclerosis and ischemia-reperfusion injury. Synonyms: BAY 60-6583; BAY-60-6583; BAY60-6583. 2-[[6-Amino-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]-2-pyridinyl]thio]-acetamide; BR 4887. Grades: ≥98% by HPLC. CAS No. 910487-58-0. Molecular formula: C19H17N5O2S. Mole weight: 379.44. | |
| BAY 60-6583 | BAY 60-6583 is a potent and selective adenosine A2B receptor agonist. BAY 60-6583 shows protective effects against ischemia in both the heart and kidney in animal models. BAY 60-6583 is also a useful therapeutic drug in the treatment of acute lung injury. Group: Biochemicals. Alternative Names: 2- [ [6-Amino-3, 5-dicyano-4- [4- (cyclopropylmethoxy) phenyl] -2-pyridinyl] thio] acetamide; BR 4887. Grades: Highly Purified. CAS No. 910487-58-0. Pack Sizes: 10mg, 25mg. Molecular Formula: C19H17N5O2S. US Biological Life Sciences. | Worldwide |
| BAY 60-6583-13C2,15N | BAY 60-6583-13C2,15N. Group: Biochemicals. Alternative Names: 2- [ [6-Amino-3, 5-dicyano-4- [4- (cyclopropylmethoxy) phenyl] -2-pyridinyl] thio] acetamide-13C2, 15N; BR 4887-13C2,15N. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C1713C2H17N415NO2S, Molecular Weight: 382.41. US Biological Life Sciences. | Worldwide |
| Bay 60-7550 | Bay 60-7550 is a potent PDE2 inhibitor. It is 50-fold more selective for PDE2 compared to PDE1 and greater than 100-fold selective compared to PDE5 PDE3B, PDE4B, PDE7B, PDE8A, PDE9A, PDE10A, and PDE11A. Synonyms: BAY60-7550; BAY 60-7550; BAY-60-7550; BAY-607550; BAY 607550; BAY607550. Grades: >98%. CAS No. 439083-90-6. Molecular formula: C27H32N4O4. Mole weight: 476.57. | |
| BAY 60-7550 | The compound induced anxiety by inhibition of. Group: Biochemicals. Alternative Names: 2-[ (3, 4-Dimethoxyphenyl) methyl]-7-[ (1R) -1-[ (1R) -1-hydroxyethyl]-4-phenylbutyl]-5-methyl-imidazo[5, 1-f][1, 2, 4]triazin-4 (1H) -one. Grades: Highly Purified. CAS No. 439083-90-6. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| BAY 61-3606 | BAY 61-3606 is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity with no inhibitory effect against Btk, Fyn, Itk, Lyn, and Src. Synonyms: BAY 61-3606; BAY 613606; BAY 61 3606; BAY-61-3606; BAY613606; BAY61 3606. Grades: >98%. CAS No. 732983-37-8. Molecular formula: C20H18N6O3. Mole weight: 390.4. | |
| BAY 61-3606 dihydrochloride | BAY 61-3606 is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity with no inhibitory effect against Btk, Fyn, Itk, Lyn, and Src. Synonyms: BAY 61-3606 dihydrochloride; BAY-61-3606 dihydrochloride; BAY61-3606 dihydrochloride. Grades: >98%. CAS No. 648903-57-5. Molecular formula: C20H18N6O3.2HCl. Mole weight: 463.32. | |
| BAY 61-3606 hydrochloride | BAY 61-3606 is a cell-permeable, reversible inhibitor of spleen tyrosine kinase (Syk; Ki=7.5 nM; IC50=10 nM). It is 700 to >1,000-fold more selective for Syk over Src, Lyn, Fyn, Itk, and Btk. BAY 61-3606 can inhibit degranulation (IC50 = 5-46 nM) and block cytokine release from mast cells. It shows good in vivo efficacy in the treatment of various allergy and asthma conditions in rat models. This compound has been used in a pre-clinical model to explore the feasibility of targeting Syk in the treatment of retinoblastoma. Synonyms: 2-[[7-(3,4-dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino]-3-pyridinecarboxamide monohydrochloride; BAY 61-3606 HCl. Grades: ≥98%. CAS No. 1615197-10-8. Molecular formula: C20H18N6O3·HCl. Mole weight: 426.9. | |
| Bay 61-3606 Hydrochloride (2-[[7- (3, 4-Dimethoxyphenyl) imidazo[1, 2-c]pyrimidin-5-yl]amino]pyridine-3-carboxamide, HCl) | Cell-permeable. A potent, ATP-competitive and reversible inhibitor of spleen tyrosine kinase (Syk) (IC50 = 10nM). Displays excellent selectivity against many other kinases including Btk, Fyn, Itk, Lyn and Src up to concentrations of 4.7uM. Shows good in vivo efficacy in the treatment of various allergy and asthma conditions in rat models. Group: Biochemicals. Alternative Names: 2-[[7- (3, 4-Dimethoxyphenyl) imidazo[1, 2-c]pyrimidin-5-yl]amino]pyridine-3-carboxamide, HCl. Grades: Highly Purified. CAS No. 732938-37-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Bay 65-1942 free base | Bay 65-1942 is an ATP-competitive inhibitor that selectively targets IKKβ kinase. Synonyms: BAY 65-1942; BAY-65-1942; BAY65-1942; BAY 651942; BAY-651942; BAY651942. BAY65-1942 free base. Grades: >98%. CAS No. 600734-02-9. Molecular formula: C22H25N3O4. Mole weight: 395.45. | |
| Bay 65-1942 hydrochloride | Bay 65-1942 hydrochloride is an ATP-competitive inhibitor that selectively targets IKKβ kinase. Synonyms: KINK-1; KINK 1; KINK1; Bay65-1942 Hydrochloride; Bay651942 Hydrochloride; Bay65-1942 HCl; Bay651942 HCl. Grades: >98%. CAS No. 600734-06-3. Molecular formula: C22H26ClN3O4. Mole weight: 431.91. | |
| Bay 65-1942 R form | Bay 65-1942 R form is an ATP-competitive inhibitor that selectively targets IKKβ kinase. Synonyms: Bay 65-1942. Grades: >98%. CAS No. 758683-21-5. Molecular formula: C22H25N3O4. Mole weight: 395.45. | |
| BAY-671 | BAY-671 is developed from the structure of BRD4 inhibitor used for the treatment of solid tumor. Studies in vtro and in vivo indicated that it has inhibitory effect on multiple cancer types. Uses: The treatment of solid tumor. Synonyms: BAY 671; BAY671. | |
| BAY 677 | BAY 677 is an inactive control for BAY 678 and a human neutrophil elastase (HNE) inhibitor. Synonyms: BAY-677; BAY 677; BAY677; 5-[(4S)-5-Acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-2-pyridinecarbonitrile. Grades: ≥98% by HPLC. CAS No. 2117404-84-7. Molecular formula: C20H15F3N4O2. Mole weight: 400.35. | |
| BAY 678 | BAY 678 is a cell-permeable human neutrophil elastase (HNE) inhibitor (IC50 = 20 nM) that displays around 2000-fold selectivity for NHE over a panel of 21 other serine proteases. Synonyms: BAY 678; BAY678; BAY-678; 5-[(4R)-5-Acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-2-pyridinecarbonitrile. Grades: ≥98% by HPLC. CAS No. 675103-36-3. Molecular formula: C20H15F3N4O2. Mole weight: 400.35. | |
| BAY-707 | BAY-707 is a substrate-competitive, highly potent and selective inhibitor of MTH1(NUDT1) with an IC 50 of 2.3 nM. BAY-707 has a good pharmacokinetic (PK) profile to other MTH1 compounds and is well-tolerated in mice, but shows a clear lack of in vitro or in vivo anticancer efficacy [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2109805-96-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112081. | |
| BAY-721973 | BAY-721973 is a bio-active chemical,but few detailed information has been published yet. Synonyms: BAY-721973; BAY 721973; BAY721973; Sorafenib metabolite M3; UNII-83F1Z938Q0; 4- (4- ( ( ( (4-chloro-3- (trifluoromethyl) phenyl) amino) carbonyl) amino) phenoxy) -N- (hydroxymethyl) -2-Pyridinecarboxamide. Grades: 98%. CAS No. 1380310-94-0. Molecular formula: C21H16ClF3N4O4. Mole weight: 480.83. | |
| BAY 73-4506 | BAY 73-4506 Inhibitor. Uses: Scientific use. Product Category: T1792. CAS No. 755037-03-7. |  |
| BAY 73-6691 | BAY 73-6691 is a phosphodiesterase inhibitor selective for the PDE9A subtype under the development of Bayer. It selectively inhibits human PDE9 with IC50 value of 55 nM in vitro.BAY 73-6691 was developed for the treatment of Alzheimer's disease, but pre-clinical research is at an early stage. Uses: Alzheimer's disease. Synonyms: BAY-73-6691; BAY736691; BAY73-6691; UNII-80ZTV3INTW; (R)-Bay-73-6691; 1-(2-Chlorophenyl)-6-[(2R)-3,3,3-trifluoro-2-methylpropyl]-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidine-4-one. Grades: 98%. CAS No. 794568-92-6. Molecular formula: C15H12ClF3N4O. Mole weight: 356.73. | |
| BAY-754 | BAY-754 is an ALK-1 inhibitor used as an anti-angiogenesis agent. It inhibited the eye vascular leakage in dose manner in mouse model. Uses: The treatment of eye disorders. Synonyms: BAY-754; BAY 754; BAY-54. | |
| BAY-8002 | BAY-8002 is a novel potent, selective, orally available monocarboxylate transporter 1 (MCT1) inhibitor (Kd=7.9 nM), which inhibits cellular lactate uptake in DLD-1 cells with IC50 of 85 nM. BAY-8002 significantly increases intratumor lactate levels and transiently modulated pyruvate levels. Synonyms: BAY 8002BAY-8002; BAY 8002; BAY8002; 2-(2-chloro-5-(phenylsulfonyl)benzamido)benzoic acid. Grades: ≥98%. CAS No. 724440-27-1. Molecular formula: C20H14ClNO5S. Mole weight: 415.85. | |
| BAY8040 | This active molecular is a Selective Human Neutrophil Elastase Inhibitor and combines excellent potency and selectivity with a promising pharmacokinetic profile. In animal models for pulmonary arterial hypertension, BAY8040 shows the efficancy of decreasing cardiac remodeling and amelioration of cardiac function in vivo. Uses: Cardiac remodeling and amelioration of cardiac function. Synonyms: BAY8040; BAY-8040; BAY 8040; (R)-4-(7-methyl-2,5-dioxo-1-(3-(trifluoromethyl)phenyl)-1,2,3,4,5,6,7,8-octahydropyrimido[4,5-d]pyridazin-4-yl)benzonitrile. Grades: 98%. CAS No. 1194453-23-0. Molecular formula: C21H16F3N5O2. Mole weight: 427.39. | |
| BAY 826 | BAY-826 is a selective and potent TIE-2 inhibitor with Kd of 1.6 nM and IC50 of 1.3 nM for autophosphorylation. BAY-826 is highly selective against other angiogenic kinases, such as VEGFR, FGFR, or PDGFR, and affects VEGF-stimulated proliferation of HUVEC. It displays in vivo efficacy in some murine glioma models. Synonyms: [3-Cyano-5- [ [ [2, 4-dimethyl-5- [6- (3-pyridinyl) -1H-imidazo [1, 2-b] pyrazol-1-yl] phenyl] amino] carbonyl] phenyl] pentafluorosulfur. Grades: ≥98% by HPLC. CAS No. 1448316-08-2. Molecular formula: C26H19F5N6OS. Mole weight: 558.53. | |
| BAY-850 | BAY-850 is a potent isotype-selective ATPase family AAA domain protein 2 (ATAD2) inhibitor with IC50 of 166 nM and can be used as a probe. Grades: 98%. CAS No. 2099142-76-2. Molecular formula: C38H44ClN5O3. Mole weight: 654.2. | |
| BAY 85-8501 | This active molecular is a highly selective neutrophil elastase inhibitor.IC50 for HNE is 0.065 nM, LipE is 7.2. BAY 85-8501 was being tested in clinical studies for the treatment of pulmonary diseases. In Feb 2013, Phase-II clinical trials in Bronchiectasis in Spain were on going. In Mar 2013, Phase-II clinical trials in Bronchiectasis in France, Germany and Italy were on going. In Jun 2014, Bayer completed a phase IIa trial in Bronchiectasis in United Kingdom, Spain, France, Germany and Italy. Uses: The treatment of pulmonary diseases. Synonyms: BAY 85-8501; BAY85-8501; BAY-85-8501; BAY 858501; BAY858501; BAY-858501. (S)-4-(4-cyano-2-(methylsulfonyl)phenyl)-3,6-dimethyl-2-oxo-1-(3-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydropyrimidine-5-carbonitrile. Grades: 98%. CAS No. 1161921-82-9. Molecular formula: C22H17F3N4O3S. Mole weight: 474.46. | |
| BAY 87-2243 | BAY 87-2243 inhibits HIF-1 reporter gene activity and CA9 protein expression with IC50 of 0.7 nM and 2 nM, respectively. Synonyms: BAY 872243; BAY872243; BAY-872243; BAY 87-2243; BAY87-2243; BAY-87-2243. Grades: >98%. CAS No. 1227158-85-1. Molecular formula: C26H26F3N7O2. Mole weight: 525.53. | |
| BAY-876 | BAY-876 is a potent and selective inhibitor of GLUT1, which is overexpressed in multiple cancers. Uses: Anticancer agent. Synonyms: BAY-876; BAY 876; BAY876. 4-N-[1-[(4-cyanophenyl)methyl]-5-methyl-3-(trifluoromethyl)pyrazol-4-yl]-7-fluoroquinoline-2,4-dicarboxamide. Grades: 95%. CAS No. 1799753-84-6. Molecular formula: C24H16F4N6O2. Mole weight: 496.426. | |
| BAY-876 | BAY-876 Inhibitor. Uses: Scientific use. Product Category: T3713. CAS No. 1799753-84-6. | |
| BAY-876 | BAY-876 is an orally active and selective glucose transporter 1 (GLUT1) inhibitor with an IC 50 of 2 nM. BAY-876 is >130-fold more selective for GLUT1 than GLUT2, GLUT3, and GLUT4. BAY-876 is also a potent blocker of glycolytic metabolism and ovarian cancer growth. In addition, BAY-876 can induce the formation of disulfide bonds in actin cytoskeletal proteins, leading to the occurrence of cellular disulfidptosis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1799753-84-6. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100017. | |
| BAY-985 | BAY-985 is a highly effective, orally active and selective TANK-binding kinase 1 (TBK1) and IκB kinase ε dual inhibitor, with anti-tumor activity. Synonyms: BAY985; GTPL10597; EX-A3294. Grades: ≥98% by HPLC. CAS No. 2409479-29-2. Molecular formula: C27H30F3N9O. Mole weight: 553.6. | |
| Bayberry Extract | Bayberry Extract. Applications: Used for health care products, dietary supplements, herb medecine and cosmetic industry. Group: Others. Synonyms: Bayberry Extract; 529-44-2; Myrica rubra sieb. Et Zucc. CAS No. 529-44-2. Purity: 50%-98% Myricitrin by HPLC, 5-10:1 by TLC. Appearance: Light yellow green fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Bark. Species: Myrica rubra sieb. Et Zucc. Bayberry Extract; 529-44-2; Myrica rubra sieb. Et Zucc; plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-128. |  |
| Bayberry Myrica Rubra Fruit P.E. 80% Myricetin HPLC | Bayberry Myrica Rubra Fruit P.E. 80% Myricetin HPLC. |  CA, FL & NJ |
| BAYBERRY WAX | BAYBERRY WAX. Uses: Designed for use in research and industrial production. Additional or Alternative Names: MYRTLE WAX;BAYBERRY WAX;MYRICA CERIFERA (BAYBERRY) FRUIT WAX;Fats, bayberry. Product Category: Heterocyclic Organic Compound. CAS No. 8038-77-5. Purity: N/A. Product ID: ACM8038775. Alfa Chemistry ISO 9001:2015 Certified. |  |
| BayCysLT2 | BayCysLT2 is a potent and selective antagonist for the CysLT2R, which attenuates exacerbation of infarction damage to the myocardium caused by endothelial CysLT2R overexpression. CysLT2R can influence myocardial damage post-ischemia/reperfusion by mediating leukocyte adhesion and infiltration. CysLT2R can further blockade post-infarction maintains its protective properties, indicating a possible therapeutic role for CysLT2R antagonism. BayCysLT2 inhibits radioligand binding of LTD4 to CysLT2 and CysLT1 receptor cell lines with IC50 values of 35 and >10,000 nM, respectively. Synonyms: CAY10633; 3-[[(3-carboxycyclohexyl)amino]carbonyl]-4-[3-[4-(4-phenoxybutoxy)phenyl]propoxy]-benzoic acid. Grades: ≥95%. CAS No. 712313-33-2. Molecular formula: C34H39NO8. Mole weight: 589.7. | |
| Bayer9017 | Bayer9017 is a bio-active chemical compound. Synonyms: Bayer 9017; Bayer-9017; 3,5-Xylenol, 4-(methylthio)-, O-ester with O,O-diethyl phosphorothioate; Phosphorothioic acid, O-(3,5-dimethyl-4-(methylthio)phenyl) O,O-diethyl ester; BAY 9017. Grades: 98%. CAS No. 52-60-8. Molecular formula: C13H21O3PS2. Mole weight: 320.43. | |
| Bayferrox | Bayferrox - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. |  North America & APAC |
| Bay K 8644 | Bay K 8644 ((±)-Bay K 8644) is a racemate consisting of two isomers (R)-(+)-Bay-K-8644 and (S)-(-)-Bay-K-8644 [1]. Bay K 8644 is a L-type Ca 2+ channel agonist with an EC 50 of 17.3 nM. Bay K 8644 increases Ca 2+ influx through sarcolemmal Ca 2+ channels by increasing the open time of the channel. Bay K 8644 has vasoconstrictive effects [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-Bay K 8644. CAS No. 71145-03-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10588. | |
| Bayogenin | Bayogenin. Group: Biochemicals. Grades: Plant Grade. CAS No. 6989-24-8. Pack Sizes: 10mg. Molecular Formula: C30H48O5, Molecular Weight: 488.7. US Biological Life Sciences. | Worldwide |
| Bayogenin 3-O- β-D-glucopyranoside | Bayogenin 3-O- β-D-glucopyranoside. Group: Biochemicals. CAS No. 104513-86-2. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Bayogenin 3-O-β-D-glucopyranoside | Bayogenin 3-O-β-D-glucopyranoside is a triterpenoid saponin isolated from the aerial parts of Polygala japonica Houtt. Synonyms: 2beta,23-Dihydroxy-3beta-(beta-D-glucopyranosyloxy)oleana-12-ene-28-oic acid. Grades: >98%. CAS No. 104513-86-2. Molecular formula: C36H58O10. Mole weight: 650.85. | |
| Bay Oil Natural | Bay Oil Natural. CAS No. MIXTURE. Kosher: Y. VIGON Item # 508413. Categories: Speciality Ingredients Suppliers, Flavors, Fragrances, Perfumers, Cosmetics, Aromatherapy, Essential Oils. |  America & Internationally |
| Bay Oil Terpeneless | Bay Oil Terpeneless. CAS No. 68916-05-2. Kosher: Y. VIGON Item # 501494. Categories: Speciality Ingredients Suppliers, Flavors, Fragrances, Perfumers, Cosmetics. | America & Internationally |
| BAY-u 3405 | BAY-u 3405. Group: Biochemicals. Grades: Purified. CAS No. 116649-85-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BAY-u 9773 | BAY-u 9773. Group: Biochemicals. Grades: Purified. CAS No. 154978-38-8. Pack Sizes: 50ug. US Biological Life Sciences. | Worldwide |
| BAY-u 9773 | BAY-u 9773 is a non-selective cysteinyl leukotriene receptor antagonist displaying equal affinity for both CysLT1 and CysLT2 receptors (pKB = 6.8 and 6.5, respectively). BAY-u 9773 was investigated to inhibit bronchial and venous muscle contractions in human muscle preparations. BAY-u 9773 also acts as a competitive antagonist of LTC4- and LTE4-induced contractions of the guinea pig trachea. Synonyms: BAYu9773; BAY-u9773; BAY u9773. 4-[[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-Carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]thio]benzoic acid; 6(R)-(4-Carboxyphenylthio)-5(S)-hydroxy-7(E),9(E),11(E),14(Z)-eicosatetraenoic acid. CAS No. 154978-38-8. Molecular formula: C27H36O5S. Mole weight: 472.64. | |
| BAY-X 1005 | BAY-X 1005. Group: Biochemicals. Grades: Purified. CAS No. 128253-31-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| BAY-X-1005 | BAY-X 1005 is a potent and selective FLAP (5-lipoxygenase-activating protein) inhibitor. BAY-X 1005 is also a selective inhibitor of leukotriene synthesis. BAY-X1005 inhibited LTB4 synthesis with IC50 values of 220 nM for isolated PMNL of human and inhibited LTC4 synthesis with IC50 value of 210 nM in mouse macrophages. Phase-III for Myocardial infarction in USA was suspended in 2006. Uses: Myocardial infarction. Synonyms: BAY-X-1005; BAY X 1005; BAYX1005; Veliflapon;DG-031; DG 031; DG031; (2R)-2-cyclopentyl-2-[4-(quinolin-2-ylmethoxy)phenyl]acetic acid. Grades: >98 %. CAS No. 128253-31-6. Molecular formula: C23H23NO3. Mole weight: 361.43. | |
| BAY-Y 3118 | BAY-Y 3118 is a 4-quinolone with outstanding antimicrobial activity against Gramnegative and Gram-positive pathogens as well as anaerobic and intracellular bacteria and might be an important contribution to progress in anti-infective therapy. Synonyms: 7-[(4aS,7aS)-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridin-6-yl]-8-chloro-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylic acid; 1-cyclopropyl-7-(2,8-diazabicyclo(4.3.0)non-8-yl)-6-fluoro-8-chloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid hydrochloride; Bay y 3118; Bay Y3118; Bay-Y3118. CAS No. 151213-16-0. Molecular formula: C20H21ClFN3O3. Mole weight: 405.85. | |
| BAZ2-ICR | BAZ2-ICR is a bromodomain inhibitor with IC50 of 130 nM for BAZ2A and IC50 of 180 nM for BAZ2B. It demonstrates 15-fold selectivity for binding BAZ2A/B over CECR2 and >100-fold selectivity over all other bromodomains. Synonyms: 4-(4-(1-methyl-1H-pyrazol-4-yl)-1-(2-(1-methyl-1H-pyrazol-4-yl)ethyl)-1H-imidazol-5-yl)benzonitrile; BAZ2ICR. Grades: ≥98%. CAS No. 1665195-94-7. Molecular formula: C20H19N7. Mole weight: 357.41. | |
| Bazedoxifene | Bazedoxifene (TSE-424) is an oral, BBB-penetrant nonsteroidal selective estrogen receptor modulator (SERM) , with IC 50 s of 23 nM and 99 nM for ERα and ERβ, respectively. Bazedoxifene can be used for the research of osteoporosis. Bazedoxifene also acts as an inhibitor of IL-6/GP130 protein-protein interactions and can be used for the research of pancreatic cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TSE-424. CAS No. 198481-32-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0031. | |
| Bazedoxifene-4'-Glucuronide | Bazedoxifene-4'-Glucuronide is a metabolite of Bazedoxifene. Synonyms: Bazedoxifene 4'-β-D-Glucuronide; [1-[[4-[2-(Hexahydro-1H-azepin-1-yl)ethoxy]phenyl]Methyl]-5-hydroxy-3-Methyl-1H-indol-2-yl]phenyl β-D-Glucopyranosiduronic Acid. Grades: > 95%. CAS No. 328933-64-8. Molecular formula: C36H42N2O9. Mole weight: 646.74. | |
| Bazedoxifene-5-Glucuronide | Bazedoxifene-5-Glucuronide is a metabolite of Bazedoxifene. Synonyms: Bazedoxifene 5-β-D-Glucuronide; 1-[[4-[2-(Hexahydro-1H-azepin-1-yl)ethoxy]phenyl]Methyl]-2-(4-hydroxyphenyl)-3-Methyl-1H-indol-5-yl β-D-Glucopyranosiduronic Acid. Grades: > 95%. CAS No. 328933-56-8. Molecular formula: C36H42N2O9. Mole weight: 646.74. | |
| Bazedoxifene acetate | Bazedoxifene, also known as WAY-140424, is a third generation selective estrogen receptor modulator (SERM), developed by Pfizer following the completion of their takeover of Wyeth Pharmaceuticals. In late 2013, Pfizer received approval for bazedoxifene as part of the combination drug DUAVEE in the prevention (not treatment) of postmenopausal osteoporosis. Bazedoxifene is an indole-based ER ligand that binds to both ERα (IC50 = 26 nM) and ERβ (IC50 = 99 nM). Uses: Designed for use in research and industrial production. Additional or Alternative Names: Bazedoxifene acetate, WAY-140424; WAY140424; WAY 140424; TSE 424; TSE424; TSE-424; Viviant. Product Category: Others. Appearance: Solid powder. CAS No. 198481-33-3. Molecular formula: C32H38N2O5. Mole weight: 530.67. Purity: >96%. IUPACName: 1-(p-(2-(Hexahydro-1H-azepin-1-yl)ethoxy)benzyl)-2-(p-hydroxyphenyl)-3-methylindol-5-ol acetic acid. Canonical SMILES: OC1=CC2=C(C=C1)N(C(C3=CC=C(C=C3)O)=C2C)CC4=CC=C(C=C4)OCCN5CCCCCC5.CC(O)=O. Product ID: ACM198481333. Alfa Chemistry ISO 9001:2015 Certified. | |
| Bazedoxifene acetate | Bazedoxifene acetate, also called as TSE424 or WAY-140424, is a selective nonsteroidal estrogen receptor modulator (SERM) with antiosteoporotic activity (ERα: IC50= 26 nM; ERβ= 99 nM). Uses: Bone density conservation agents. Synonyms: TSE 424; TSE-424; TSE424; WAY-140424; WAY 140424; WAY140424. Grades: 95%. CAS No. 198481-33-3. Molecular formula: C32H38N2O5. Mole weight: 530.66. | |
| Bazedoxifene acetate | Bazedoxifene acetate (TSE-424 acetate) is an oral, nonsteroidal selective estrogen receptor modulator (SERM) , with IC 50 s of 23 nM and 99 nM for ERα and ERβ, respectively. Bazedoxifene acetate can be used for the research of osteoporosis. Bazedoxifene acetate also acts as an inhibitor of IL-6/GP130 protein-protein interactions and can be used for the research of pancreatic cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TSE-424 acetate. CAS No. 198481-33-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-A0036. | |
| Bazedoxifene Acetate | Bazedoxifene Acetate is a nonsteroidal selective estrogen receptor modulator (SERM). Bazedoxifene Acetate is used as an antiosteoporotic. Group: Biochemicals. Alternative Names: 1-[[4-[2- (Hexahydro-1H-azepin-1-yl) ethoxy]phenyl]methyl]-2- (4-hydroxyphenyl) -3-methyl-. Grades: Highly Purified. CAS No. 198481-33-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Bazedoxifene (acetate)-B | Bazedoxifene (acetate)-B (TSE-424 (acetate)-B) is the B-crystal form compound of Bazedoxifene acetate (HY-A0036). Bazedoxifene acetate is an orally active, nonsteroidal selective estrogen receptor modulator (SERM), with IC 50 s of 23 nM and 99 nM for ERα and ERβ, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TSE-424 (acetate)-B. CAS No. 198481-33-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0036B. | |
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