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| Product | Description | |
|---|---|---|
| BC-1215 | BC-1215 is an inhibitor of F-box protein 3 (FBXO3) with an IC50 of 0.9 μg/mL for IL-1β release. It acts by antagonizing Fbxo3 in TRAF cell signaling and displays a low IC50 in vitro. BC-1215 can be used for inflammation research. Synonyms: N1,N2-bis[[4-(2-pyridinyl)phenyl]methyl]-1,2-ethanediamine. Grade: ≥98%. CAS No. 1507370-20-8. Molecular formula: C26H26N4. Mole weight: 394.51. |  |
| BC-1215 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| BC-1258 | BC-1258 is an F-box/LRR-repeat protein 2 (FBXL2) activator. BC-1258 stabilized and increased levels of FBXL2 protein that promoted Aurora B degradation, resulting in tetraploidy, mitotic arrest and apoptosis of tumorigenic cells, and profoundly inhibiting tumor formation in athymic nude mice. Synonyms: BC 1258; BC1258; N1,N2-Bis(4-(thiazol-2-yl)benzyl)ethane-1,2-diamine. Grade: >98%. CAS No. 1507370-40-2. Molecular formula: C22H22N4S2. Mole weight: 406.57. | |
| BC1618 | BC1618 is an orally active inhibitor of F-box only protein 48 (FBXO48) that stimulates Ampk-dependent signaling. BC1618 promotes mitochondrial fission, facilitates autophagy and improves hepatic insulin sensitivity in high-fat-diet-induced obese mice. Synonyms: BC-1618; BC 1618. CAS No. 2222094-18-8. Molecular formula: C24H24F3NO2. Mole weight: 415.45. | |
| BC2059 | BC2059 is a novel β-catenin antagonist and its treatment dose-dependently induced apoptosis of cultured and primary AML BPCs. BC2059 also significantly improved the median survival of immune-depleted mice engrafted with either cultured or primary AML BPCs, showing nuclear expression of β-catenin. Synonyms: BC2059; BC-2059; BC 2059; (9E,10E)-2,7-bis(((3R,5S)-3,5-dimethylpiperidin-1-yl)sulfonyl)anthracene-9,10-dione dioxime. Grade: 98%. CAS No. 1227637-23-1. Molecular formula: C28H36N4O6S2. Mole weight: 588.74. | |
| BC8-15 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BCA | BCA (Disodium bicinchoninate) is an orally active and non-competitive Beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor with an IC 50 value of 28 μM, a K i value of 43 μM. BCA shows anticancer activity. BCA has the potential for the research of Alzheimer's disease (AD) [1] [2] [3]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Disodium bicinchoninate. CAS No. 979-88-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-15908. |  |
| BCAA Powder (2:1:1) | BCAA Powder (2:1:1). |  CA, FL & NJ |
| B-CARBOXYASPARTIC ACID | B-CARBOXYASPARTIC ACID. Uses: Designed for use in research and industrial production. Additional or Alternative Names: d,l-trans-Chrysanthemsaeure-butylester; 2-amino-3-carboxybutanedioic acid; butyl 2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropanecarboxylate. Product Category: Heterocyclic Organic Compound. CAS No. 75898-26-9. Molecular formula: C5H7NO6. Mole weight: 177.112180 [g/mol]. Purity: 0.96. IUPACName: 2-aminoethane-1,1,2-tricarboxylic acid. Density: 1.782g/cm³. Product ID: ACM75898269. Alfa Chemistry ISO 9001:2015 Certified. Categories: beta-Carboxyaspartic acid. |  |
| b-Carotene 5,6-epoxide | b-Carotene 5,6-epoxide. Group: Biochemicals. Alternative Names: (5RS,6RS)-5,6-Epoxy-5,6-dihydro-b,b-carotene. Grades: Highly Purified. Pack Sizes: 1mg, 2mg, 5mg. US Biological Life Sciences. |  Worldwide |
| b-Carotenone | b-Carotenone. Group: Biochemicals. Alternative Names: 5,6,5',6'-Diseco-b,b-carotene-5,6,5',6'-tetrone. Grades: Highly Purified. Pack Sizes: 1mg, 2mg, 5mg. US Biological Life Sciences. | Worldwide |
| b-Caryophyllene oxide | b-Caryophyllene oxide. Group: Biochemicals. Grades: Highly Purified. CAS No. 1139-30-6. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C15H24O. US Biological Life Sciences. | Worldwide |
| b-Casomorphin (1-3) acetate | b-Casomorphin (1-3) acetate is a tripeptide with opioid effects. Synonyms: H-Tyr-Pro-Phe-OH.CH3CO2H; YPF acetate; L-tyrosyl-L-prolyl-L-phenylalanine acetic acid. Grade: ≥95%. CAS No. 2763583-71-5. Molecular formula: C23H27N3O5.C2H4O2. Mole weight: 485.53. | |
| Bcat | Bcat. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BCAT;Benzotriazole-1-carboxamidinium tosylate. Product Category: Heterocyclic Organic Compound. CAS No. 163853-10-9. Molecular formula: C7H8N5.C7H7O3S. Mole weight: 333.37. Product ID: ACM163853109. Alfa Chemistry ISO 9001:2015 Certified. Categories: BCATP. | |
| BCAT | BCAT. Synonyms: Benzotriazole-1-Carboxamidinium Tosylate; 1H-Benzotriazole-1-carboximidamide, 4-methylbenzenesulfonate (1:1). Grade: 95%. CAS No. 163853-10-9. Molecular formula: C7H8N5.C7H7O3S. Mole weight: 333.37. | |
| BCATc Inhibitor 2 | BCATc Inhibitor 2 is a selective branched-chain aminotransferase (BCAT) inhibitor for research of neurodegenerative diseases. The IC50s of 0.2 ?M, 0.8 ?M and 3.0 ?M for rat cytosolic isoenzyme rBCATc, human cytosolic isoenzyme hBCATc and rat mitochondrial isoenzyme rBCATm, respectively. BCATc, also called BCAT1, is in the cytoplasm[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 406191-34-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116044. | |
| BCATc Inhibitor 2 | BCATc Inhibitor 2 is a sulfonyl hydrazide that inhibits BCATc with IC50s of 0.81 for human and IC50 s of 0.2 μM for rat. It is 15-fold selectivity over BCATm. It has also been used to block calcium influx into neurons with IC50 of 4.8 μM following inhibition of glutamate uptake and to demonstrate neuroprotective efficacy in an in vivo rat model of neurodegeneration. Synonyms: Cytosolic Branched-Chain Amino Acid Transferase Inhibitor 2. Grade: ≥98%. CAS No. 406191-34-2. Molecular formula: C16H10ClF3N2O4S. Mole weight: 418.8. | |
| b-Catenin/Tcf Inhibitor II, PKF118-310 (1,6-Dimethylpyrimido[5,6-e][1,2,4]triazine-5,7-dione, Wnt Pathway Inhibitor IV) | A synthetic cell-permeable actinobacteria pyrimidotriazine-dione that selectively disrupts b-catenin-Tcf4 interaction (IC50=0.8uM in cell-free binding assays) and inhibits b-catenin-regulated cellular transcription activity (IC50=0.3uM in HCT116-based reporter assays). PKF118-310 is demonstrated to reverse b-catenin, but not siamois, mRNA-induced ventral body axis formation in Xenopus embryos, while direct tumor site injection (1mg/kg/0.5 wk) in HepG2 xenograph mice is shown to increase the number of apoptotic cells and decrease the expression of b-catenin target genes (cyclin D1, c-Myc, survivin) in the tumor mass, resulting in an effective tumor growth retardation (by ~60% after a 4-wk treatment period) in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| b-Catenin/Tcf Inhibitor V, BC21 (Copper, di-u-chlorobis[1-[(1-piperidinyl-kN)methyl]-2-naphthalenolato-kO]di-(9Cl), Wnt Pathway Inhibitor XV) | A cell-permeable dimeric copper complex that competitively binds b-catenin and disrupts b-catenin/Tcf4 interaction reversibly (IC50=5.0uM), and acts as a Wnt signaling inhibitor. Shown to induce preferential growth arrest in b-catenin overexpressing HCT116 colon cancer and HEK293 cells (≤10uM), and downregulate mRNA expressions of c-Myc and cyclin D1. Reported to inhibit PP2C and proteasomal activities at higher concentrations (~50uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 691005-38-6. Pack Sizes: 10mg. Molecular Formula: C32H36Cl2Cu2N2O2, Molecular Weight: 678.6. US Biological Life Sciences. | Worldwide |
| BCAT-IN-2 | BCAT-IN-2 is a potent, selective and orally active inhibitor of mitochondrial branched-chain aminotransferase (BCATm), with a pIC50 of 7.3. BCAT-IN-2 shows selectivity for BCATm over BCATc (pIC50=6.6). BCAT-IN-2 can be used for the research of obesity and dislipidema[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1800024-45-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141669. | |
| bcbp | bcbp. Group: Organic light-emitting diode (oled) materials. CAS No. 858131-70-1. Product ID: 9-[4-[2-[2- (4-carbazol-9-ylphenyl) phenyl]phenyl]phenyl]carbazole. Molecular formula: 636.8g/mol. Mole weight: C48H32N2. C1=CC=C (C (=C1) C2=CC=C (C=C2) N3C4=CC=CC=C4C5=CC=CC=C53) C6=CC=CC=C6C7=CC=C (C=C7) N8C9=CC=CC=C9C1=CC=CC=C18. InChI=1S/C48H32N2/c1-3-15-39 (37 (13-1)33-25-29-35 (30-26-33)49-45-21-9-5-17-41 (45)42-18-6-10-22-46 (42)49)40-16-4-2-14-38 (40)34-27-31-36 (32-28-34)50-47-23-11-7-19-43 (47)44-20-8-12-24-48 (44)50/h1-32H. UXJDSNKBYFJNDO-UHFFFAOYSA-N. |  |
| BCC-TPTA | BCC-TPTA. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 9'- [4- (4, 6- Diphenyl- 1, 3, 5- triazin- 2- yl) phenyl] -9, 3':6', 9''- ter- 9H- carbazole. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1361093-61-9. Molecular formula: C57H36N6. Mole weight: 804.94 g/mol. Product ID: ACM1361093619. Alfa Chemistry ISO 9001:2015 Certified. | |
| BCDA | BCDA (5-bromo-4-chloroindoxyl acetate) is a chromogenic substrate of esterase used to potently detect the activity of esterase [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: 5-bromo-4-chloroindoxyl acetate. CAS No. 3252-36-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-52112. | |
| BCECF | BCECF is a pH-sensitive fluorescent dye. BCECF allows measurements in the physiological pH range 6.0 - 8.0. Excitation ratio: 490/440 nm; Emission intensity: 535 nm. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: 2,7-Bis(2-carboxyethyl)-5(6)-carboxyfluorescein. CAS No. 85138-49-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-101882. | |
| BCECF acid | BCECF acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2',7'-bis-(2-carboxyethyl)-5-(and-6)-carboxyfluorescein. Product Category: Fluorescein Fluorophores. CAS No. 85138-49-4. Molecular formula: C27H20O11. Mole weight: 520.45. Product ID: ACM85138494. Alfa Chemistry ISO 9001:2015 Certified. | |
| Bcecf-am | Bcecf-am. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SPIRO(ISOBENZOFURAN-1(3H),9'-(9H)XANTHENE)-2',7'-DIPROPANOIC ACID;BCECF-AM;2',7'-BIS-(CARBOXYETHYL)-5(6')-CARBOXYFLUORESCEIN ACETOXYMETHYL ESTER;2',7'-BIS-(2-CARBOXYETHYL)-5-(AND-6)-CARBOXYFLUORESCEIN, ACETOXYMETHYL ESTER;2,7-BIS(2-CARBOXYETHYL)-5,6-CARB. Product Category: Heterocyclic Organic Compound. CAS No. 134331-92-3. Molecular formula: C42H40O21. Mole weight: 880.75. Product ID: ACM134331923. Alfa Chemistry ISO 9001:2015 Certified. | |
| BCECF-AM | BCECF-AM. Group: Biochemicals. Grades: Purified. CAS No. 117464-70-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| BCECF-AM | BCECF-AM is a cell membrane permeable compound widely used as a fluorescent indicator for intracellular pH. Uses: Scientific research. Group: Fluorescent dye. CAS No. 117464-70-7. Pack Sizes: 205 μg (5 mM * 50 μL in DMSO); 410 μg (5 mM * 100 μL in DMSO); 820 μg (5 mM * 200 μL in DMSO); 2.05 mg (5 mM * 500 μL in DMSO). Product ID: HY-101883. | |
| BCECF, AM | BCECF, AM. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2',7'-bis-(2-carboxyethyl)-5-(and-6)-carboxyfluorescein, acetoxymethyl ester. Product Category: Fluorescein Fluorophores. Appearance: White powder. CAS No. 117464-70-7. Molecular formula: C39H36O19. Mole weight: 808.69. Purity: 90%+. Product ID: ACM117464707. Alfa Chemistry ISO 9001:2015 Certified. Categories: Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-2',7'-dipropanoic acid. | |
| BCECF/AM - CAS 117464-70-7 | A variable mixture of cell-permeable ester derivatives of BCECF that are hydrolyzed by cytosolic esterases to yield intracellularly trapped indicator BCECF. Group: Fluorescence/luminescence spectroscopy. | |
| b-Cellobiosyl azide | b-Cellobiosyl azide is a highly versatile biomedical compound, acting as a precursor for synthesizing glycoconjugates and glycosylated natural drugs. Leveraging its profound influence on protein function and stability, this remarkable compound has become extensively utilized in cutting-edge drug development and advanced pharmaceutical investigations. Synonyms: 4-O-b-D-Glucopyranosyl-b-D-glucopyranosyl azide. CAS No. 69194-62-3. Molecular formula: C12H21N3O10. Mole weight: 367.3. | |
| b-Cembrenediol | b-Cembrenediol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: beta-Cembrenediol, ( )-beta-Cembratrienediol, CCRIS 5452, CCRIS 5453, beta-4,8,13-Duvatriene-1,3-diol, beta-2,7,11-Cembratriene-4,6-diol, CID6440192, (1R-(1R*,3R*,4E,8E,12S*,13E))-1,5,9-Trimethyl-12-(1-methylethyl)-4,8,13-cyclotetradecatriene-1,3-diol, 4,8,13-Cyclotetradecatriene-1,3-diol, 1,5,9-trimethyl-12-(1-methylethyl)-, (1R,3R,4E,8E,12S,13E)-, 4,8,13-Cyclotetradecatriene-1,3-diol, 1,5,9-trimethyl-12-(1-methylethyl)-, (1R-(1R*,3R*,4E,8E,12S*,13E))-, 57605-81-9, 58190-98-0. Product Category: Heterocyclic Organic Compound. CAS No. 57605-81-9. Molecular formula: C20H34O2. Mole weight: 306.48. Purity: 0.96. IUPACName: (1R,3R,4Z,8Z,12S,13Z)-1,5,9-trimethyl-12-propan-2-ylcyclotetradeca-4,8,13-triene-1,3-diol. Canonical SMILES: CC1=CCCC(=CC(CC(C=CC(CC1)C(C)C)(C)O)O)C. Product ID: ACM57605819. Alfa Chemistry ISO 9001:2015 Certified. | |
| BCG Vaccine | BCG Vaccine is a vaccine primarily used against tuberculosis (TB). BCG also has some effectiveness against Buruli ulcer infection and other nontuberculous mycobacterial infections. Additionally, it is sometimes used as part of the treatment of bladder cancer. Synonyms: Bacillus Calmette. | |
| BCH | BCH is an inhibitor of L-type amino acid transporter (LAT1), which is a therapeutic target for human esophageal squamous cell carcinoma. BCH inhibits growth and induces apoptosis via activation of caspases in KB, Saos2 and C6 cancer cell lines. Synonyms: 2-Aminobicyclo[2.2.1]heptane-2-carboxylic acid. CAS No. 20448-79-7. Molecular formula: C8H13NO2. Mole weight: 155.2. | |
| BCH | BCH. Group: Biochemicals. Grades: Purified. CAS No. 20448-79-7. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| BCH | BCH (2-Amino-2-norbornanecarboxylic acid) is a selective and competitive inhibitor of large neutral amino acid transporter 1 (LAT1) significantly inhibit cellular uptake of amino acids and mTOR phosphorylation, which induces the suppression of cancer growth and apoptosis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2-Amino-2-norbornanecarboxylic acid; LAT1-IN-1. CAS No. 20448-79-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-108540. | |
| BCH001 | BCH001 is a specific PAPD5 inhibitor. BCH001 restores telomerase activity and telomere length in DC patient induced pluripotent stem cells. Synonyms: 2-((3-(Ethoxycarbonyl)-6-(trifluoromethoxy)quinolin-4-yl)amino)benzoicacid. CAS No. 384859-58-9. Molecular formula: C20H15F3N2O5. Mole weight: 420.34. | |
| BCH001 | BCH001, a quinoline derivative, is a specific PAPD5 inhibitor. BCH001 restores telomerase activity and telomere length in dyskeratosis congenita (DC) induced pluripotent stem cells. BCH001 shows no inhibition of poly(A)-specific ribonuclease (PARN) or several other canonical and non-canonical polynucleotide polymerases. BCH001 is used to regulate aging[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 384859-58-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137817. | |
| BChE-IN-17 | BChE-IN-17 (compound 6n) is a potent and selective BChE inhibitor with IC 50 s of 10.5 nM and 32.5 nM for eqBChE and hBChE , respectively. BChE-IN-17 shows over 1000-fold selectivity to BChE against AChE. BChE-IN-17 shows low neurotoxicity and moderate neuroprotective effects [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2425632-57-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155140. | |
| BChE inhibitor 8012-9656 | BChE inhibitor 8012-9656 is a potent and selective inhibitor of butyrylcholinsterase (BChE). It inhibits BChE in a noncompetitive manner and could occupy the binding pocket forming diverse interactions with the target. Synonyms: 2-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1H-benzo[d]imidazol-1-yl)-N-(2-methylquinolin-6-yl)acetamide. Grade: 98%. CAS No. 446266-84-8. Molecular formula: C21H17N7O2. Mole weight: 399.41. | |
| b-Chloralose | b-Chloralose is a renowned compound employed for the research of sedation and anesthesia functioning as a central nervous system depressant. Uses: Anesthetics, intravenous. Synonyms: beta-Chloralose; (R)-1-((2S,3aR,5R,6S,6aR)-6-hydroxy-2-(trichloromethyl)tetrahydrofuro[2,3-d][1,3]dioxol-5-yl)ethane-1,2-diol. CAS No. 16376-36-6. Molecular formula: C8H11Cl3O6. Mole weight: 309.53. | |
| b-Chloro-D-alanine 99+% (TLC) | b-Chloro-D-alanine 99+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| b-Chloro-DL-alanine hydrochloride 98+% (TLC) | b-Chloro-DL-alanine hydrochloride 98+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g. US Biological Life Sciences. | Worldwide |
| b-Chloro-L-alanine ≥95% (HPLC) | b-Chloro-L-alanine ≥95% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| b-Chloro-L-alanine hydrochloride | b-Chloro-L-alanine hydrochloride. Synonyms: b-Chloro-L-Ala-OH HCl; (R)-2-Amino-3-chloropropionic acid hydrochloride; 3-Chloro-L-alanine Hydrochloride; beta-Chloro-L-alanine hydrochloride; L-Alanine, 3-chloro-, hydrochloride; 3-Chloro-l-alanine HCl; H-Ala(3-Cl)-OH HCl. Grade: ≥ 95% (HPLC). CAS No. 51887-89-9. Molecular formula: C3H6NO2Cl·HCl. Mole weight: 160.00. | |
| b-Chloro-L-alanine hydrochloride | b-Chloro-L-alanine hydrochloride. Group: Biochemicals. Alternative Names: b-Chloro-L-Ala-OH·HCl; (R)-2-Amino-3-chloropropionic acid hydrochloride. Grades: Highly Purified. CAS No. 51887-89-9. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C3H6NO2Cl·HCl. US Biological Life Sciences. | Worldwide |
| b-Chloro-L-alanine hydrochloride ≥95% (HPLC) | b-Chloro-L-alanine hydrochloride ≥95% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| b-Chloro-L-alanine methyl ester hydrochloride 98+% (TLC) | b-Chloro-L-alanine methyl ester hydrochloride 98+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| b-Cholestanol | b-Cholestanol. Group: Biochemicals. Alternative Names: 5a-Cholestan-3b-ol. Grades: Highly Purified. CAS No. 80-97-7. Pack Sizes: 2g, 5g, 10g, 25g, 50g. Molecular Formula: C27H48O. US Biological Life Sciences. | Worldwide |
| BCI | BCI is an allosteric inhibitor of dual-specificity phosphatases (DUSP). BCI treatment of DUSP6-Myc-transfected cells suppresses DUSP6 or DUSP1 activity. BCI induces expansion of myocardial progenitors that ultimately increases heart size in zebrafish embryos via inhibiting DUSP6. BCI also inhibits lung cancer and uveal melanoma cells viability (IC50 = 0.1 to 90 μM). DUSP6 functions a feedback regulator of fibroblast growth factor (FGF) signaling to limit the activity of extracellular signal-regulated kinases (ERKs) 1 and 2. Synonyms: (E)-2-benzylidene-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one; (2E)-2-Benzylidene-3-(cyclohexylamino)-1-indanone. Grade: 99%. CAS No. 1245792-51-1. Molecular formula: C22H23NO. Mole weight: 317.42. | |
| BCI | BCI ((E)-BCI) is a DUSP6 ( dual specificity phosphatase 6 ) inhibitor. BCI shows anti-inflammatory activity and decreases reactive oxygen species (ROS) production. BCI can be used in inflammatory disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (E)-BCI. CAS No. 1245792-51-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-115502. | |
| BCI-121 | BCI-121, a SMYD3 inhibitor, induces a significant reduction in SMYD3 activity both in vitro and in CRC cells. Synonyms: 1-[2-(4-bromoanilino)-2-oxoethyl]piperidine-4-carboxamide; 1-(2-((4-bromophenyl)amino)-2-oxoethyl)piperidine-4-carboxamide; 1-{2-[(4-bromophenyl)amino]-2-oxoethyl}piperidine-4-carboxamide; BAS 04914128; AC1LGJJ6. CAS No. 432529-82-3. Molecular formula: C14H18BrN3O2. Mole weight: 340.22. | |
| BCI-121 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BCI-137 | BCI-137 is a competitive Argonaute 2 (Ago2) ligand (IC50 = 342 μM) that acts by targeting the MicroRNA binding domain. Synonyms: Alanine, N-[(1,2,3,4-tetrahydro-2,3-dioxo-6-quinoxalinyl)sulfonyl]-; DL-Alanine, N-[(1,2,3,4-tetrahydro-2,3-dioxo-6-quinoxalinyl)sulfonyl]-; N-[(1,2,3,4-Tetrahydro-2,3-dioxo-6-quinoxalinyl)sulfonyl]alanine; 2-(2,3-Dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonamido)propanoic acid; BCI 137; BCI137. Grade: 95%. CAS No. 112170-24-8. Molecular formula: C11H11N3O6S. Mole weight: 313.29. | |
| BCI-137 | BCI-137 is a competitive AGO2 inhibitor, with an IC50 of 342 ?M. BCI-137 tightly binds to several residues of the Mid domain[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 112170-24-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-119024. | |
| BCI-215 | BCI-215 is a potent and tumor cell-selective dual specificity MAPK phosphatase (DUSP-MKP) inhibitor. BCI-215 has cytotoxicity for tumor cells but not normal cells[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1245792-67-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121087. | |
| BCI hydrochloride | BCI ((E)-BCI) hydrochloride is a DUSP6 ( dual specificity phosphatase 6 ) inhibitor. BCI hydrochloride shows anti-inflammatory activity and decreases reactive oxygen species (ROS) production. BCI hydrochloride can be used in inflammatory disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (E)-BCI hydrochloride. CAS No. 95130-23-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115502A. | |
| BCI hydrochloride | BCI hydrochloride is an allosteric inhibitor of Dusp6, acting within the phosphatase domain to prevent the catalytic stimulation of phosphatase activity induced by ERK2 substrate binding. BCI also inhibits lung cancer and uveal melanoma cells viability (IC50 values ranging from 0.1 to 90 μM). It prevents pERK2 dephosphorylation induced by Dusp6 in vitro. It is selective for Dusp6 and Dusp1 over Dusp3/VHR, Cdc25B, and PTP1B, for which it has no activity. Synonyms: 2-Benzylidene-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one hydrochloride. Grade: ≥95%. CAS No. 95130-23-7. Molecular formula: C22H23NO·HCl. Mole weight: 353.9. | |
| BCIP | BCIP(BCIP p-toluidine salt; X-phosphate p-toluidine salt) is an artificial chromogenic substrate used for the sensitive colorimetric detection of alkaline phosphatase activity [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: BCIP p-toluidine salt; X-phosphate p-toluidine salt. CAS No. 6578-6-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-15909. | |
| BCIP Na) 5-Bromo-4-chloro-3-indolyl phosphate disodium salt | 1g Pack Size. Group: Building Blocks, Stains & Indicators. Formula: C8H4BrClNO4Na2P. CAS No. 102185-33-1. Prepack ID 67003351-1g. Molecular Weight 370.43. See USA prepack pricing. |  |
| BCIP-Toluidine)5-Bromo-4-chloro-3-indolylphosphate-p-toluidine salt | 1g Pack Size. Group: Analytical Reagents, Biochemicals, Diagnostic Raw Materials. Formula: C8H5BrClNO4P ·C7H10N. CAS No. 6578-6-9. Prepack ID 21540524-1g. Molecular Weight 433.62. See USA prepack pricing. | |
| BCL-10 human | recombinant, expressed in insect cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| Bcl-2 Active human | recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| Bcl-2 Binding Peptide, cell permeable | It is a peptide that binds to Bcl-2 with high affinity. It is derived from the BH3 domain (a death domain) of Bad, amino acid residues 140 to 165, and is cellular permeable due to the N-terminal modification by a decanoyl moiety. Synonyms: Decanoyl-Lys-Asn-Leu-Trp-Ala-Ala-Gln-Arg-Tyr-Gly-Arg-Glu-Leu-Arg-Arg-Met-Ser-Asp-Glu-Phe-Glu-Gly-Ser-Phe-Lys-Gly-Leu-OH; N-decanoyl-L-lysyl-L-asparagyl-L-leucyl-L-tryptophyl-L-alanyl-L-alanyl-L-glutaminyl-L-arginyl-L-tyrosyl-glycyl-L-arginyl-L-alpha-glutamyl-L-leucyl-L-arginyl-L-arginyl-L-methionyl-L-seryl-L-alpha-aspartyl-L-alpha-glutamyl-L-phenylalanyl-L-alpha-glutamyl-glycyl-L-seryl-L-phenylalanyl-L-lysyl-glycyl-L-leucine. Grade: ≥95% by HPLC. Molecular formula: C153H240N44O42S. Mole weight: 3399.93. | |
| Bcl-2, C-Terminal Truncated, His Tag, Human, Recombinant, E. coli | Recombinant, human Bcl-2 without the 17 amino acid mitochondrial targeting sequence at the C-terminus,and expressed in E. coli. Group: Fluorescence/luminescence spectroscopy. | |
| BCL2, GST tagged human | recombinant, expressed in E. coli, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| BCL2-IN-1 | BCL2-IN-1, a potent Bcl-2 inhibitor, binds Bcl-2 with a Ki of <0.01 nM. Synonyms: 4-(4-{[2-(4-Chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl}-1-piperazinyl)-N-[(4-{[(trans-4-methoxycyclohexyl)methyl]amino}-3-nitrophenyl)sulfonyl]-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide; Benzamide, 4-[4-[[2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(trans-4-methoxycyclohexyl)methyl]amino]-3-nitrophenyl]sulfonyl]-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-. Grade: 98%. CAS No. 1257044-75-9. Molecular formula: C47H54ClN7O7S. Mole weight: 896.49. | |
| Bcl-2-IN-2 | Bcl-2-IN-2 is a potent and selective Bcl-2 inhibitor with an IC50 of 0.034 nM, and also inhibits Bcl-xL with an IC50 of 43 nM, showing >1000-fold selectivity for Bcl-2 over Bcl-xL. Synonyms: (S)-2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(2-(2-(2-ethylphenyl)pyrrolidin-1-yl)-7-azaspiro[3.5]nonan-7-yl)-N-((4-(((4-hydroxy-4-methylcyclohexyl)methyl)amino)-3-nitrophenyl)sulfonyl)benzamide. Grade: ≥95%. CAS No. 2383085-86-5. Molecular formula: C48H57N7O7S. Mole weight: 876.07. | |
| Bcl-2-like protein 1 (173-182) | Bcl-2-like protein 1 (173-182) is a 10-aa peptide. Bcl-2-like protein 1 is a potent inhibitor of cell death. It inhibits activation of caspases. Synonyms: Bcl2-L-1 (173-182); Apoptosis regulator Bcl-X (173-182). | |
| BCL6-IN-4 | BCL6-IN-4 is a potent inhibitor of B-cell lymphoma 6 (BCL6) with an IC50 of 97 nM. BCL6-IN-4 has antitumor activity. Synonyms: 2H-Benzimidazol-2-one, 5-[[5-chloro-2-(2,2,6,6-tetramethyl-4-morpholinyl)-4-pyrimidinyl]amino]-1,3-dihydro-3-(3-hydroxy-3-methylbutyl)-1-methyl-; 5-{[5-Chloro-2-(2,2,6,6-tetramethyl-4-morpholinyl)-4-pyrimidinyl]amino}-3-(3-hydroxy-3-methylbutyl)-1-methyl-1,3-dihydro-2H-benzimidazol-2-one. Grade: ≥98%. CAS No. 2253879-65-9. Molecular formula: C25H35ClN6O3. Mole weight: 503.04. | |
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