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| Product | Description | |
|---|---|---|
| BC-11 hydrobromide | BC-11 hydrobromide is a selective TMPRSS2 inhibitor (TMPRSS2 is a key host cellular factor for viral entry and SARS-CoV-2 pathogenesis), and a selective urokinase ( uPA ) inhibitor ( IC 50 =8.2 μM). BC-11 hydrobromide is cytotoxic to triple-negative MDA-MB231 breast cancer cells. BC-11 hydrobromide is used in research on viral infections and cancer [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 443776-49-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-108447. |  |
| BC-1215 | BC-1215 is an inhibitor of F-box protein 3 (FBXO3) with an IC50 of 0.9 μg/mL for IL-1β release. It acts by antagonizing Fbxo3 in TRAF cell signaling and displays a low IC50 in vitro. BC-1215 can be used for inflammation research. Synonyms: N1,N2-bis[[4-(2-pyridinyl)phenyl]methyl]-1,2-ethanediamine. Grades: ≥98%. CAS No. 1507370-20-8. Molecular formula: C26H26N4. Mole weight: 394.51. |  |
| BC2059 | BC2059 is a novel β-catenin antagonist and its treatment dose-dependently induced apoptosis of cultured and primary AML BPCs. BC2059 also significantly improved the median survival of immune-depleted mice engrafted with either cultured or primary AML BPCs, showing nuclear expression of β-catenin. Synonyms: BC2059; BC-2059; BC 2059; (9E,10E)-2,7-bis(((3R,5S)-3,5-dimethylpiperidin-1-yl)sulfonyl)anthracene-9,10-dione dioxime. Grades: 98%. CAS No. 1227637-23-1. Molecular formula: C28H36N4O6S2. Mole weight: 588.74. | |
| BCA | BCA (Disodium bicinchoninate) is an orally active and non-competitive Beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor with an IC 50 value of 28 μM, a K i value of 43 μM. BCA shows anticancer activity. BCA has the potential for the research of Alzheimer's disease (AD) [1] [2] [3]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Disodium bicinchoninate. CAS No. 979-88-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-15908. | |
| BCAA Powder (2:1:1) | BCAA Powder (2:1:1). |  CA, FL & NJ |
| b-Carotene 5,6-epoxide | b-Carotene 5,6-epoxide. Group: Biochemicals. Alternative Names: (5RS,6RS)-5,6-Epoxy-5,6-dihydro-b,b-carotene. Grades: Highly Purified. Pack Sizes: 1mg, 2mg, 5mg. US Biological Life Sciences. |  Worldwide |
| b-Carotenone | b-Carotenone. Group: Biochemicals. Alternative Names: 5,6,5',6'-Diseco-b,b-carotene-5,6,5',6'-tetrone. Grades: Highly Purified. Pack Sizes: 1mg, 2mg, 5mg. US Biological Life Sciences. | Worldwide |
| b-Caryophyllene oxide | b-Caryophyllene oxide. Group: Biochemicals. Grades: Highly Purified. CAS No. 1139-30-6. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C15H24O. US Biological Life Sciences. | Worldwide |
| b-Casomorphin (1-3) acetate | b-Casomorphin (1-3) acetate is a tripeptide with opioid effects. Synonyms: H-Tyr-Pro-Phe-OH.CH3CO2H; YPF acetate; L-tyrosyl-L-prolyl-L-phenylalanine acetic acid. Grades: ≥95%. CAS No. 2763583-71-5. Molecular formula: C23H27N3O5.C2H4O2. Mole weight: 485.53. | |
| B-CASOMORPHIN BOVINE ACETATE | Heterocyclic Organic Compound. Alternative Names: B-CASOMORPHIN BOVINE ACETATE. CAS No. 100900-42-3. Catalog: ACM100900423. |  |
| b-Casomorphin fragment 1-3bovine hydroch loride | Heterocyclic Organic Compound. Alternative Names: B-CASOMORPHIN FRAGMENT 1-3BOVINE HYDROCH LORIDE;beta-casomorphin fragment 1-3 bovine hydrochloride;β-Casomorphin Fragment1-3 hydrochloride. CAS No. 100900-18-3. Molecular formula: C23H27N3O5.ClH. Mole weight: 461.943. Purity: 0.96. IUPACName: (2S)-2-[[(2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoicacid;hydrochloride. Canonical SMILES: C1CC (N (C1)C (=O)C (CC2=CC=C (C=C2)O)N)C (=O)NC (CC3=CC=CC=C3)C (=O)O. Cl. Catalog: ACM100900183. | |
| BCAT | Synonyms: Benzotriazole-1-Carboxamidinium Tosylate; 1H-Benzotriazole-1-carboximidamide, 4-methylbenzenesulfonate (1:1). Grades: 95%. CAS No. 163853-10-9. Molecular formula: C7H8N5.C7H7O3S. Mole weight: 333.37. | |
| BCATc Inhibitor 2 | BCATc Inhibitor 2 is a sulfonyl hydrazide that inhibits BCATc with IC50s of 0.81 for human and IC50 s of 0.2 μM for rat. It is 15-fold selectivity over BCATm. It has also been used to block calcium influx into neurons with IC50 of 4.8 μM following inhibition of glutamate uptake and to demonstrate neuroprotective efficacy in an in vivo rat model of neurodegeneration. Synonyms: Cytosolic Branched-Chain Amino Acid Transferase Inhibitor 2. Grades: ≥98%. CAS No. 406191-34-2. Molecular formula: C16H10ClF3N2O4S. Mole weight: 418.8. | |
| b-Catenin/Tcf Inhibitor II, PKF118-310 (1,6-Dimethylpyrimido[5,6-e][1,2,4]triazine-5,7-dione, Wnt Pathway Inhibitor IV) | A synthetic cell-permeable actinobacteria pyrimidotriazine-dione that selectively disrupts b-catenin-Tcf4 interaction (IC50=0.8uM in cell-free binding assays) and inhibits b-catenin-regulated cellular transcription activity (IC50=0.3uM in HCT116-based reporter assays). PKF118-310 is demonstrated to reverse b-catenin, but not siamois, mRNA-induced ventral body axis formation in Xenopus embryos, while direct tumor site injection (1mg/kg/0.5 wk) in HepG2 xenograph mice is shown to increase the number of apoptotic cells and decrease the expression of b-catenin target genes (cyclin D1, c-Myc, survivin) in the tumor mass, resulting in an effective tumor growth retardation (by ~60% after a 4-wk treatment period) in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| b-Catenin/Tcf Inhibitor V, BC21 (Copper, di-u-chlorobis[1-[(1-piperidinyl-kN)methyl]-2-naphthalenolato-kO]di-(9Cl), Wnt Pathway Inhibitor XV) | A cell-permeable dimeric copper complex that competitively binds b-catenin and disrupts b-catenin/Tcf4 interaction reversibly (IC50=5.0uM), and acts as a Wnt signaling inhibitor. Shown to induce preferential growth arrest in b-catenin overexpressing HCT116 colon cancer and HEK293 cells (≤10uM), and downregulate mRNA expressions of c-Myc and cyclin D1. Reported to inhibit PP2C and proteasomal activities at higher concentrations (~50uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 691005-38-6. Pack Sizes: 10mg. Molecular Formula: C32H36Cl2Cu2N2O2, Molecular Weight: 678.6. US Biological Life Sciences. | Worldwide |
| bcbp | bcbp. Group: Organic light-emitting diode (oled) materials. CAS No. 858131-70-1. Product ID: 9-[4-[2-[2- (4-carbazol-9-ylphenyl) phenyl]phenyl]phenyl]carbazole. Molecular formula: 636.8g/mol. Mole weight: C48H32N2. C1=CC=C (C (=C1) C2=CC=C (C=C2) N3C4=CC=CC=C4C5=CC=CC=C53) C6=CC=CC=C6C7=CC=C (C=C7) N8C9=CC=CC=C9C1=CC=CC=C18. InChI=1S/C48H32N2/c1-3-15-39 (37 (13-1)33-25-29-35 (30-26-33)49-45-21-9-5-17-41 (45)42-18-6-10-22-46 (42)49)40-16-4-2-14-38 (40)34-27-31-36 (32-28-34)50-47-23-11-7-19-43 (47)44-20-8-12-24-48 (44)50/h1-32H. UXJDSNKBYFJNDO-UHFFFAOYSA-N. |  |
| BCDA | BCDA (5-bromo-4-chloroindoxyl acetate) is a chromogenic substrate of esterase used to potently detect the activity of esterase [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: 5-bromo-4-chloroindoxyl acetate. CAS No. 3252-36-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-52112. | |
| BCECF | BCECF is a pH-sensitive fluorescent dye. BCECF allows measurements in the physiological pH range 6.0 - 8.0. Excitation ratio: 490/440 nm; Emission intensity: 535 nm. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: 2,7-Bis(2-carboxyethyl)-5(6)-carboxyfluorescein. CAS No. 85138-49-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-101882. | |
| BCECF-AM | BCECF-AM is a cell membrane permeable compound widely used as a fluorescent indicator for intracellular pH. Uses: Scientific research. Group: Fluorescent dye. CAS No. 117464-70-7. Pack Sizes: 205 μg (5 mM * 50 μL in DMSO); 410 μg (5 mM * 100 μL in DMSO); 820 μg (5 mM * 200 μL in DMSO); 2.05 mg (5 mM * 500 μL in DMSO). Product ID: HY-101883. | |
| BCECF-AM | BCECF-AM. Group: Biochemicals. Grades: Purified. CAS No. 117464-70-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| BCECF, AM | Fluorescein Fluorophores. Alternative Names: 2',7'-bis-(2-carboxyethyl)-5-(and-6)-carboxyfluorescein, acetoxymethyl ester. CAS No. 117464-70-7. Molecular formula: C39H36O19. Mole weight: 808.69. Appearance: White powder. Purity: 90%+. Catalog: ACM117464707. | |
| b-Cellobiosyl azide | b-Cellobiosyl azide is a highly versatile biomedical compound, acting as a precursor for synthesizing glycoconjugates and glycosylated natural drugs. Leveraging its profound influence on protein function and stability, this remarkable compound has become extensively utilized in cutting-edge drug development and advanced pharmaceutical investigations. Synonyms: 4-O-b-D-Glucopyranosyl-b-D-glucopyranosyl azide. CAS No. 69194-62-3. Molecular formula: C12H21N3O10. Mole weight: 367.3. | |
| BCFG | Heterocyclic Organic Compound. Alternative Names: BCFG. CAS No. 114205-89-9. Catalog: ACM114205899. | |
| BCG Vaccine | BCG Vaccine is a vaccine primarily used against tuberculosis (TB). BCG also has some effectiveness against Buruli ulcer infection and other nontuberculous mycobacterial infections. Additionally, it is sometimes used as part of the treatment of bladder cancer. Synonyms: Bacillus Calmette. | |
| BCH | BCH (2-Amino-2-norbornanecarboxylic acid) is a selective and competitive inhibitor of large neutral amino acid transporter 1 (LAT1) significantly inhibit cellular uptake of amino acids and mTOR phosphorylation, which induces the suppression of cancer growth and apoptosis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2-Amino-2-norbornanecarboxylic acid; LAT1-IN-1. CAS No. 20448-79-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-108540. | |
| BCH | BCH is an inhibitor of L-type amino acid transporter (LAT1), which is a therapeutic target for human esophageal squamous cell carcinoma. BCH inhibits growth and induces apoptosis via activation of caspases in KB, Saos2 and C6 cancer cell lines. Synonyms: 2-Aminobicyclo[2.2.1]heptane-2-carboxylic acid. CAS No. 20448-79-7. Molecular formula: C8H13NO2. Mole weight: 155.2. | |
| BCH | BCH. Group: Biochemicals. Grades: Purified. CAS No. 20448-79-7. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| BChE-IN-17 | BChE-IN-17 (compound 6n) is a potent and selective BChE inhibitor with IC 50 s of 10.5 nM and 32.5 nM for eqBChE and hBChE , respectively. BChE-IN-17 shows over 1000-fold selectivity to BChE against AChE. BChE-IN-17 shows low neurotoxicity and moderate neuroprotective effects [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2425632-57-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155140. | |
| b-Chloralose | b-Chloralose is a renowned compound employed for the research of sedation and anesthesia functioning as a central nervous system depressant. Uses: Anesthetics, intravenous. Synonyms: beta-Chloralose; 16376-36-6; 7CUN2U7N0Q; DTXSID4046575; (1R)-1-[(2S,3aR,5R,6S,6aR)-6-hydroxy-2-(trichloromethyl)-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl]ethane-1,2-diol; alpha-D-Glucofuranose, 1,2-O-[(1S)-2,2,2-trichloroethylidene]-; (R)-1-((2S,3aR,5R,6S,6aR)-6-hydroxy-2-(trichloromethyl)tetrahydrofuro[2,3-d][1,3]dioxol-5-yl)ethane-1,2-diol; |A-Chloralose; UNII-7CUN2U7N0Q; NSC-52806; NCGC00166244-01; EINECS 240-429-2.BETA.-CHLORALOSE; SCHEMBL9714720; DTXCID2026575; OJYGBLRPYBAHRT-GVUNPQSCSA-N; (S)-1,2-O-(2,2,2-Trichloroethylidene)-alpha-D-glucofuranose; Tox21_112370; NSC 52806; AKOS015913708; CAS-16376-36-6; CS-0447761; W-204208; Q27268085; A-D-GLUCOFURANOSE,1,2-O-[(1S)-2,2,2-TRICHLOROETHYLIDENE]-.ALPHA.-D-GLUCOFURANOSE, 1,2-O-((1S)-2,2,2-TRICHLOROETHYLIDENE)-CHLORALOSE. BETA.-. CAS No. 16376-36-6. Molecular formula: C8H11Cl3O6. Mole weight: 309.53. | |
| b-Chloro-D-alanine 99+% (TLC) | b-Chloro-D-alanine 99+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| b-Chloro-DL-alanine hydrochloride 98+% (TLC) | b-Chloro-DL-alanine hydrochloride 98+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g. US Biological Life Sciences. | Worldwide |
| b-Chloro-L-alanine ≥95% (HPLC) | b-Chloro-L-alanine ≥95% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| b-Chloro-L-alanine hydrochloride | Synonyms: b-Chloro-L-Ala-OH HCl; (R)-2-Amino-3-chloropropionic acid hydrochloride; 3-Chloro-L-alanine Hydrochloride; beta-Chloro-L-alanine hydrochloride; L-Alanine, 3-chloro-, hydrochloride; 3-Chloro-l-alanine HCl; H-Ala(3-Cl)-OH HCl. Grades: ≥ 95% (HPLC). CAS No. 51887-89-9. Molecular formula: C3H6NO2Cl·HCl. Mole weight: 160.00. | |
| b-Chloro-L-alanine hydrochloride | b-Chloro-L-alanine hydrochloride. Group: Biochemicals. Alternative Names: b-Chloro-L-Ala-OH·HCl; (R)-2-Amino-3-chloropropionic acid hydrochloride. Grades: Highly Purified. CAS No. 51887-89-9. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C3H6NO2Cl·HCl. US Biological Life Sciences. | Worldwide |
| b-Chloro-L-alanine hydrochloride ≥95% (HPLC) | b-Chloro-L-alanine hydrochloride ≥95% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| b-Chloro-L-alanine methyl ester hydrochloride 98+% (TLC) | b-Chloro-L-alanine methyl ester hydrochloride 98+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| b-Cholestanol | b-Cholestanol. Group: Biochemicals. Alternative Names: 5a-Cholestan-3b-ol. Grades: Highly Purified. CAS No. 80-97-7. Pack Sizes: 2g, 5g, 10g, 25g, 50g. Molecular Formula: C27H48O. US Biological Life Sciences. | Worldwide |
| BCI | BCI is an allosteric inhibitor of dual-specificity phosphatases (DUSP). BCI treatment of DUSP6-Myc-transfected cells suppresses DUSP6 or DUSP1 activity. BCI induces expansion of myocardial progenitors that ultimately increases heart size in zebrafish embryos via inhibiting DUSP6. BCI also inhibits lung cancer and uveal melanoma cells viability (IC50 = 0.1 to 90 μM). DUSP6 functions a feedback regulator of fibroblast growth factor (FGF) signaling to limit the activity of extracellular signal-regulated kinases (ERKs) 1 and 2. Synonyms: (E)-2-benzylidene-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one; (2E)-2-Benzylidene-3-(cyclohexylamino)-1-indanone. Grades: 99%. CAS No. 1245792-51-1. Molecular formula: C22H23NO. Mole weight: 317.42. | |
| BCI | BCI ((E)-BCI) is a DUSP6 ( dual specificity phosphatase 6 ) inhibitor. BCI shows anti-inflammatory activity and decreases reactive oxygen species (ROS) production. BCI can be used in inflammatory disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (E)-BCI. CAS No. 1245792-51-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-115502. | |
| BCI-121 | BCI-121, a SMYD3 inhibitor, induces a significant reduction in SMYD3 activity both in vitro and in CRC cells. Synonyms: 1-[2-(4-bromoanilino)-2-oxoethyl]piperidine-4-carboxamide; 1-(2-((4-bromophenyl)amino)-2-oxoethyl)piperidine-4-carboxamide; 1-{2-[(4-bromophenyl)amino]-2-oxoethyl}piperidine-4-carboxamide; BAS 04914128; AC1LGJJ6. CAS No. 432529-82-3. Molecular formula: C14H18BrN3O2. Mole weight: 340.22. | |
| BCI hydrochloride | BCI ((E)-BCI) hydrochloride is a DUSP6 ( dual specificity phosphatase 6 ) inhibitor. BCI hydrochloride shows anti-inflammatory activity and decreases reactive oxygen species (ROS) production. BCI hydrochloride can be used in inflammatory disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (E)-BCI hydrochloride. CAS No. 95130-23-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115502A. | |
| BCI hydrochloride | BCI hydrochloride is an allosteric inhibitor of Dusp6, acting within the phosphatase domain to prevent the catalytic stimulation of phosphatase activity induced by ERK2 substrate binding. BCI also inhibits lung cancer and uveal melanoma cells viability (IC50 values ranging from 0.1 to 90 μM). It prevents pERK2 dephosphorylation induced by Dusp6 in vitro. It is selective for Dusp6 and Dusp1 over Dusp3/VHR, Cdc25B, and PTP1B, for which it has no activity. Synonyms: 2-Benzylidene-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one hydrochloride. Grades: ≥95%. CAS No. 95130-23-7. Molecular formula: C22H23NO·HCl. Mole weight: 353.9. | |
| BCIP | BCIP(BCIP p-toluidine salt; X-phosphate p-toluidine salt) is an artificial chromogenic substrate used for the sensitive colorimetric detection of alkaline phosphatase activity [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: BCIP p-toluidine salt; X-phosphate p-toluidine salt. CAS No. 6578-6-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-15909. | |
| Bcip · 2 ampd | Heterocyclic Organic Compound. Alternative Names: BCIP · 2 AMPD;5-Bromo-4-chloro-3-indolylphosphate bis-(2-amino-2-methyl-1,3-propanediol)salt. CAS No. 107475-11-6. Molecular formula: C16H28BrClN3O8P. Mole weight: 536.74. Catalog: ACM107475116. | |
| Bcip dipotassium salt | Heterocyclic Organic Compound. CAS No. 102185-49-9. Molecular formula: C8H4BrClK2NO4P. Mole weight: 402.65. Catalog: ACM102185499. | |
| BCIP Na) 5-Bromo-4-chloro-3-indolyl phosphate disodium salt | 1g Pack Size. Group: Building Blocks, Stains & Indicators. Formula: C8H4BrClNO4Na2P. CAS No. 102185-33-1. Prepack ID 67003351-1g. Molecular Weight 370.43. See USA prepack pricing. |  |
| BCIP-Toluidine)5-Bromo-4-chloro-3-indolylphosphate-p-toluidine salt | 1g Pack Size. Group: Analytical Reagents, Biochemicals, Diagnostic Raw Materials. Formula: C8H5BrClNO4P ·C7H10N. CAS No. 6578-6-9. Prepack ID 21540524-1g. Molecular Weight 433.62. See USA prepack pricing. | |
| Bcl-2 Binding Peptide, cell permeable | It is a peptide that binds to Bcl-2 with high affinity. It is derived from the BH3 domain (a death domain) of Bad, amino acid residues 140 to 165, and is cellular permeable due to the N-terminal modification by a decanoyl moiety. Synonyms: Decanoyl-Lys-Asn-Leu-Trp-Ala-Ala-Gln-Arg-Tyr-Gly-Arg-Glu-Leu-Arg-Arg-Met-Ser-Asp-Glu-Phe-Glu-Gly-Ser-Phe-Lys-Gly-Leu-OH; N-decanoyl-L-lysyl-L-asparagyl-L-leucyl-L-tryptophyl-L-alanyl-L-alanyl-L-glutaminyl-L-arginyl-L-tyrosyl-glycyl-L-arginyl-L-alpha-glutamyl-L-leucyl-L-arginyl-L-arginyl-L-methionyl-L-seryl-L-alpha-aspartyl-L-alpha-glutamyl-L-phenylalanyl-L-alpha-glutamyl-glycyl-L-seryl-L-phenylalanyl-L-lysyl-glycyl-L-leucine. Grades: ≥95% by HPLC. Molecular formula: C153H240N44O42S. Mole weight: 3399.93. | |
| BCL6-IN-5 | BCL6-IN-5 is a potent BCL6 inhibitor exacted from patent WO2018215801A1, example 1n, has a pIC 50 of 5.82 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2253878-09-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136774. | |
| BCMA72-80 acetate | BCMA72-80 acetate is an HLA-A2-specific B cell maturation antigen (BCMA) peptide with a high affinity for HLA-A2 and is used to study multiple myeloma and tumors expressing B cell maturation antigens. Synonyms: H-Tyr-Leu-Met-Phe-Leu-Leu-Arg-Lys-Ile-OH.CH3CO2H; L-tyrosyl-L-leucyl-L-methionyl-L-phenylalanyl-L-leucyl-L-leucyl-L-arginyl-L-lysyl-L-isoleucine acetic acid. Grades: ≥95%. Molecular formula: C61H101N13O13S. Mole weight: 1256.60. | |
| BCMCM-caged 8-Br-cAMP | BCMCM-caged 8-Br-cAMP is a caged precursor of 8-bromo cAMP with improved solubility in water or buffers. 8-Br-cAMP and a fluorescent coumarin analogue are released by irradiation. Synonyms: [6,7-Bis(carboxymethoxy)coumarin-4-yl]methyl-8-bromoadenosine-3',5'-cyclic monophosphate. Grades: ≥ 98% by HPLC. CAS No. 370091-64-8. Molecular formula: C24H21BrN5O14P. Mole weight: 714.33. | |
| BCMCM-caged 8-Br-cGMP | BCMCM-caged 8-Br-cGMP is a caged precursor of 8-bromo cGMP with improved solubility in water or buffers. 8-Br-cGMP and a fluorescent coumarin analogue are released by irradiation. Synonyms: [6,7-Bis(carboxymethoxy)coumarin-4-yl)methyl-8-bromoguanosine-3',5'-cyclic monophosphate. Grades: ≥ 98% by HPLC. CAS No. 370091-68-2. Molecular formula: C24H21BrN5O15P. Mole weight: 730.33. | |
| BCMCM-caged cGMP | BCMCM-caged cGMP is a caged precursor of cGMP, the second messenger, which has improved solubility in water or buffers. cGMP and a fluorescent coumarin analogue are released by irradiation. Synonyms: cyclic guanosine-3',5'-monophosphate [6,7-bis(carboxymethoxy)coumarin-4-yl]methyl ester. Grades: ≥ 98% by HPLC. CAS No. 339291-52-0. Molecular formula: C24H22N5O15P. Mole weight: 651.43. | |
| BCN-3,5-diene-9-methanol | BCN-3,5-diene-9-methanol. Group: Biochemicals. Grades: Highly Purified. CAS No. 1072439-47-4. Pack Sizes: 100mg, 250mg, 500mg. Molecular Formula: C10H14O. US Biological Life Sciences. | Worldwide |
| BCN-endo-PEG4-NHS | BCN-endo-PEG4-NHS is an ADC Linker containing 4 PEG units. BCN-endo-PEG4-NHS contains the lyophilic bidentate macrocyclic ligand endo-BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts. Uses: Scientific research. Group: Signaling pathways. CAS No. 1702356-19-1. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W096079. | |
| BCN-OH | SPAAC & SPANC Click Reaction. Group: Bcn. CAS No. 1263166-90-0. Molecular formula: C10H14O. Mole weight: 150.22. IUPACName: [(1S,8R)-9-Bicyclo[6.1.0]non-4-ynyl]methanol. Canonical SMILES: C1CC2C(C2CO)CCC#C1. Density: 1.08±0.1 g/cm3(Predicted). Catalog: CCR1263166900. | |
| BCN-PEG3-VC-PFP ester | SPAAC & SPANC Click Reaction. Group: Bcn. CAS No. 2353409-45-5. Molecular formula: C37H50F5N5O10. Mole weight: 819.8. Purity: 0.96. IUPACName: (2,3,4,5,6-Pentafluorophenyl) (2S) -2- [ [ (2S) -2- [3- [2- [2- [2- [ [ (1R, 8S) -9-bicyclo [6. 1. 0] non-4-ynyl] methoxycarbonylamino] ethoxy] ethoxy] ethoxy] propanoylamino] -3-methylbutanoyl] amino] -5- (carbamoylamino) pentanoate. Canonical SMILES: CC (C)C (C (=O)NC (CCCNC (=O)N)C (=O)OC1=C (C (=C (C (=C1F)F)F)F)F)NC (=O)CCOCCOCCOCCNC (=O)OCC2C3C2CCC#CCC3. Catalog: CCR2353409455. | |
| BCN-PEG4-acid | SPAAC & SPANC Click Reaction. Group: Bcn. Alternative Names: endo-BCN-PEG4 acid. CAS No. 1881221-47-1. Molecular formula: C22H35NO8. Mole weight: 441.5. Appearance: Viscous liquid. Purity: 97%+. IUPACName: 3- [2- [2- [2- [2- [ [ (1R, 8S) -9-Bicyclo [6. 1. 0] non-4-ynyl] methoxycarbonylamino] ethoxy] ethoxy] ethoxy] ethoxy] propanoic acid. Canonical SMILES: C1CC2C (C2COC (=O)NCCOCCOCCOCCOCCC (=O)O)CCC#C1. Density: 1.20±0.1 g/cm3(Predicted). Catalog: CCR1881221471. | |
| BCN-POE3-NH2 | BCN-POE3-NH2. Group: Crosslinkers. CAS No. 1263166-93-3. Product ID: [(1R,8S)-9-bicyclo[6.1.0]non-4-ynyl]methyl N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]carbamate. Molecular formula: 324.4g/mol. Mole weight: C17H28N2O4. C1CC2C(C2COC(=O)NCCOCCOCCN)CCC#C1. InChI=1S / C17H28N2O4 / c18-7-9-21-11-12-22-10-8-19-17 (20) 23-13-16-14-5-3-1-2-4-6-15 (14) 16 / h14-16H, 3-13, 18H2, (H, 19, 20) / t14-, 15+, 16?. YZGOWXGENSKDSE-XYPWUTKMSA-N. 95%+. | |
| BCN-POE3-NH2 | Other PEG Linkers. CAS No. 1263166-93-3. Molecular formula: C17H28N2O4. Mole weight: 324.4g/mol. Purity: 95%+. IUPACName: [(1R,8S)-9-bicyclo[6.1.0]non-4-ynyl]methyl N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]carbamate. Canonical SMILES: C1CC2C(C2COC(=O)NCCOCCOCCN)CCC#C1. Catalog: ACM1263166933. | |
| BCN-SS-amine | SPAAC & SPANC Click Reaction. Group: Bcn. Alternative Names: (1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyl N-{2-[(2-aminoethyl)disulfanyl]ethyl}carbamate. CAS No. 1435784-65-8. Molecular formula: C15H24N2O2S2. Mole weight: 328.5. IUPACName: [(1R,8S)-9-Bicyclo[6.1.0]non-4-ynyl]methyl N-[2-(2-aminoethyldisulfanyl)ethyl]carbamate. Canonical SMILES: C1CC2C(C2COC(=O)NCCSSCCN)CCC#C1. Density: 1.23±0.1 g/cm3(Predicted). Catalog: CCR1435784658. | |
| B (continued) | Our wide distribution network, with locations coast-to-coast, helps guarantee fast, reliable service to Univar's customers. |  |
| b-Core-APE-HSA | | |
| BCOT-PEF3-OPFP | SPAAC & SPANC Click Reaction. Group: Bcn. CAS No. 2101206-48-6. Molecular formula: C26H30F5NO7. Mole weight: 563.5. IUPACName: 2,3,4,5,6-Pentafluorophenyl 3-{2-[2- (2-{[ ({bicyclo[6. 1. 0]non-4-yn-9-yl}methoxy) carbonyl]amino}ethoxy) ethoxy]ethoxy}propanoate. Canonical SMILES: C1CC2C (C2COC (=O)NCCOCCOCCOCCC (=O)OC3=C (C (=C (C (=C3F)F)F)F)F)CCC#C1. Catalog: CCR2101206486. | |
| BCPA | BCPA is a Pin1 regulator without cytotoxicity. BCPA attenuates the reduction of Pin1 protein to inhibit receptor activator of RANKL-induced osteoclastogenesis. BCPA regulates osteoclast activation, used to osteoporosis research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 547731-67-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153675. | |
| BCPO | BCPO. Group: Organic light-emitting diode (oled) materials. Alternative Names: 9,9'-(4,4'-(Phenylphosphoryl)bis-(4,1-phenylene))bis(9H-carbazole). CAS No. 1233407-28-7. Product ID: Bis(4-carbazol-9-ylphenyl)-phenylphosphane. Molecular formula: 608.67. Mole weight: C42H29N2P. O=P (C1=CC=C (N2C (C=CC=C3) =C3C4=C2C=CC=C4) C=C1) (C5=CC=C (N6C (C=CC=C7) =C7C8=C6C=CC=C8) C=C5) C9=CC=CC=C9. 1S/C42H29N2OP/c45-46 (32-12-2-1-3-13-32, 33-26-22-30 (23-27-33)43-39-18-8-4-14-35 (39)36-15-5-9-19-40 (36)43)34-28-24-31 (25-29-34)44-41-20-10-6-16-37 (41)38-17-7-11-21-42 (38)44/h1-29H, QBKVPXLLGMSPNX-UHFFFAOYSA-N. QBKVPXLLGMSPNX-UHFFFAOYSA-N. 95%+. | |
| BCPO | Organic Light Emitting Diode (OLED). Alternative Names: Bis-4-(N-carbazolyl)phenyl)phenylphosphine oxide. CAS No. 1233407-28-7. Molecular formula: C42H29N2OP. Mole weight: 608.67 g/mol. Appearance: White crystal. Purity: 95%+. IUPACName: Bis(4-carbazol-9-ylphenyl)-phenylphosphane. Canonical SMILES: O=P (C1=CC=C (N2C (C=CC=C3) =C3C4=C2C=CC=C4) C=C1) (C5=CC=C (N6C (C=CC=C7) =C7C8=C6C=CC=C8) C=C5) C9=CC=CC=C9. Catalog: ACM1233407287. | |
| BCR-ABL1-IN-1 | BCR-ABL1-IN-1 is a potent, orally active, and specific inhibitor of ABL kinase. BCR-ABL1-IN-1 has potential for elucidating the role of ABL kinases in the brain in non-clinical studies [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1488090-21-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145887. | |
| BCRP Inhibitor III, YHO-13177 ((Z)-2-(3,4-Dimethoxyphenyl)-3-(5-(4-hydroxypiperidin-1-yl)thiophen-2-yl)acrylonitrile) | A cell-permeable acrylonitrile compound that potently inhibits breast cancer resistance protein (BCRP/ABCG2)-mediated drug export and reverses BCRP-mediated drug resistance in vitro (half maximal in the range 0.01-1uM) without altering the BCRP expression levels (in <6hrs.). Shown to selectively enable the intracellular accumulation of anticancer drugs and potentiate the cytotoxicity of BCRP-expressing carcinoma cells with no effect either on the P-glycoprotein/ABCB1- and MDRP1-mediated export or on the drug sensitivity of parental cells (IC50>10uM in A549 cells). An in vivo bioavailable and readily water soluble prodrug of YHO-13177, BCRP Inhibitor IV, YHO-13351 is also available. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| BCRP Inhibitor IV, YHO-13351 (Diethylaminoacetic Acid, 1-(5-((Z)-2-cyano-2- (3, 4-dimethoxyphenyl) vinyl) thiophen-2-yl) piperidin-4-yl ester, Methanesulfonate) | An in vivo bioavailable (~87%; t1/2 <5 mins. during p.o. and i.v. administration) and highly water soluble (>100mg/ml) diethylaminoacetate prodrug of YHO-13177 that reverses BCRP-mediated irinotecan resistance in P388/BCRP and HCT116/BCRP xenograft mouse models, and suppresses tumor growth and significantly enhances the survival (100 or 200mg/kg, i.p.). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
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