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| Product | Description | |
|---|---|---|
| BPR1K653 | SBPR1K653 is a potent Aurora kinase inhibitor with potential anticancder activity. BPR1K653 specifically inhibited the activity of Aurora-A and Aurora-B kinase at low nano-molar concentrations in vitro. BPR1K653 was potent in targeting a variety of cancer cell lines regardless of the tissue origin, p53 status, or expression of MDR1. At the cellular level, BPR1K653 induced endo-replication and subsequent apoptosis in both MDR1-negative and MDR1-positive cancer cells. Importantly, it showed potent activity against the growth of xenograft tumors of the human cervical carcinoma KB and KB-derived MDR1-positive KB-VIN10 cells in nude mice. Finally, BPR1K653 also exhibited favorable pharmacokinetic properties in rats., BPR1K653 is a promising anti-cancer compound that has potential for the management of various malignancies, particularly for patients with MDR1-related drug resistance after prolonged chemotherapeutic treatments. Synonyms: BPR1K653; BPR1K 653; BPR1K-653. Grades: 98%. CAS No. 1192754-07-6. Molecular formula: C30H30Cl2N6O2. Mole weight: 541.04. |  |
| BPR1R024 | BPR1R024 is an orally active and selective colony-stimulating factor-1 receptor (CSF1R) inhibitor. BPR1R024 has potent CSF1R inhibition activity with an IC 50 value of 0.53 nM. BPR1R024 can be used for the research of immuno-oncology [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2503015-75-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-132935. |  |
| BPTAPA | BPTAPA. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N10,N10'-Bis(4-isopropylphenyl)-N10,N10'-di-p-tolyl-9,9'-bianthracene-10,10'-diamine. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1848973-32-9. Molecular formula: C60H52N2. Mole weight: 801.07 g/mol. Product ID: ACM1848973329. Alfa Chemistry ISO 9001:2015 Certified. Categories: Betapapillomavirus. |  |
| BPTES | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| BPTES | BPTES is a potent and selective Glutaminase GLS1 (KGA) inhibitor with IC50 of 0.16 μM. Grades: 98%. CAS No. 314045-39-1. Molecular formula: C24H24N6O2S3. Mole weight: 524.68. | |
| BPTES | BPTES is an allosteric and selective glutaminase inhibitor with an IC50 of 0.16 ?M. Uses: Scientific research. Group: Signaling pathways. CAS No. 314045-39-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-12683. | |
| BPTF-IN-BZ1 | BPTF-IN-BZ1, a BPTF inhibitor, possesses a high potency (Kd = 6.3 nM). Uses: Scientific research. Group: Signaling pathways. CAS No. 2766623-38-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132889. | |
| BPTU | BPTU is an allosteric antagonist of P2Y1 (EC50 = 0.06-0.3 μM) that binds receptors outside of the helical bundle. BPTU blocks inhibition of spontaneous contraction of rat and mouse colon, which is induced by electrical field activation, nicotine and P2Y agonists. It exhibits antithrombotic activity and reduces platelet aggregation. Uses: Antithrombotic. Synonyms: BPTU; BMS-646786; BMS 646786; BMS646786; BMS compound 16; N-[2-[2-(1,1-Dimethylethyl)phenoxy]-3-pyridinyl]-N'-[4-(trifluoromethoxy)phenyl]urea. Grades: ≥98% by HPLC. CAS No. 870544-59-5. Molecular formula: C23H22F3N3O3. Mole weight: 445.43. | |
| Bpu10I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme 80% of the dna fragments can be ligated. of these 90% can be recut. in the presence of 10% peg ligation is better. Group: Restriction Enzymes. Purity: 200U; 1000U. CC↑TNAGC GGANT↓CG. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer K. Storage: -20°C. Form: Liquid. Source: An E.coli strain, that carries recombinant plasmids. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM NaCl; 0.1 mM EDTA; 1 mM DTT; 50% glycerol. Cat No: ET-1039RE. |  |
| Bpu14 I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme about 95% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. TT↑CGAA AAGC↓TT. Activity: 10000u.a./ml. Appearance: 10 X SE-buffer G. Storage: -20°C. Form: Liquid. Source: Bacillus pumilus 14. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 50% glycerol. Cat No: ET-1040RE. | |
| bpV(bipy) | Potent protein phosphotyrosine phosphatase inhibitor Insulin mimetic in vitro and in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 1173697-60-3,42494-71-3 (anhydrous). Pack Sizes: 5mg, 25mg. Molecular Formula: K[VO(O2)2C10H8N2] 3H2O. US Biological Life Sciences. |  Worldwide |
| bpV(HOpic) | bpV(OHpic) is a bisperoxovanadium inhibitor of protein phosphotyrosine phosphatases with selectivity for PTEN, phosphatase and tensin homolog, a tumor suppressor phosphatase involved in cell cycle regulation. IC50 values for bpV(HOpic) are 14 nM for PTEN compared to 4.9 μM for PTP β and 25.3 μM for PTP-1 β. bpV(HOpic) has been shown to enhance PI3K/Akt signaling that could prevent myocardium from ischemia-reperfusion injury. Group: Biochemicals. Alternative Names: Dipotassium bisperoxo (5-hydroxypyridine-2-carboxyl) oxovanadate (V); Bisperoxovanadium (HOpic), Dipotassium bisperoxo (5-hydroxypyridine-2-carboxyl) oxovanadate (V). Grades: Highly Purified. CAS No. 722494-26-0. Pack Sizes: 5mg, 25mg. Molecular Formula: K2[VO(O2)2C6H4NO3], Molecular Weight: 347.24. US Biological Life Sciences. | Worldwide |
| bpV(HOpic) | ?90% V basis. Group: Fluorescence/luminescence spectroscopy. | |
| BpV(HOpic) | BpV(HOpic) is a potent and selective inhibitor of PTEN with an IC50 of 14 nM. Nanocarrier-BpV(HOpic) has neuroprotective activity[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Bisperoxovanadium. CAS No. 722494-26-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-128693. | |
| bpV(HOpic) potassium salt | BpV(HOpic) is a protein tyrosine phosphatases (PTPs) and a potent PTEN inhibitor with IC50 of 14 nM. It also inhibits the vascular endothelial PTP-β with IC50 of 4.9 μM and PTP-1βB with IC50 of 25.3 μM. It is reported to function as an insulin mimetic and activate the insulin receptor kinase (IRK). BpV(HOpic) has been shown to activate the insulin receptor kinase of hepatoma cells and enhance PI3K/Akt signaling, which could prevent ischemia-reperfusion (I/R) injury to the myocardium. Synonyms: Bisperoxovanadium(HOpic). Grades: ≥95%. CAS No. 722494-26-0. Molecular formula: C6H4NO8V·2K. Mole weight: 347.2. | |
| bpV(phen) | ?95% V basis. Group: Fluorescence/luminescence spectroscopy. | |
| bpV(phen) | Potent protein phosphotyrosine phosphatase inhibitor Insulin receptor kinase (IRK) inducer. Insulin mimetic in vitro and in vivo. Apoptosis inducer. ERK inducer. Mitogen-activated protein kinase phosphatase-1 (MKP-1) inducer. Angiogenesis inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 171202-16-7. Pack Sizes: 5mg, 25mg. Molecular Formula: K[VO(O2)2C12H8N2]. 3H2O. US Biological Life Sciences. | Worldwide |
| bpV(phen) (Potassium bisperoxo (1, 10-phenanthroline) oxovanadate (V)) | A bisperoxovanadium compound that acts as a potent protein phosphotyrosine phosphatase (PTP) inhibitor as well as an insulin receptor kinase (IRK) activator. Also an excellent insulin mimetic in vitro and in vivo and a potent PTEN inhibitor (IC50 = 38nM). Group: Biochemicals. Alternative Names: Potassium bisperoxo (1, 10-phenanthroline) oxovanadate (V). Grades: Highly Purified. CAS No. 42494-73-2. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| bpV(phen) potassium hydrate | BpV(phen) is a bisperoxovanadium (bpV) compound which inhibits several different protein tyrosine phosphatases (PTPs) with IC50 of 38 nM. It also inhibits the vascular endothelial PTP-β with IC50 of 343 nM and PTP-1β with IC50 of 920 nM. At 0.1 mM, bpV(phen) inhibits SH2 domain-containing inositol 5'-phosphatase-2. Presumably by inhibiting insulin receptor kinase-associated PTPs, bpV(phen) activates the insulin receptor tyrosine kinase and promotes downstream signaling, including activation of PI3-kinase. Synonyms: Bisperoxovanadium(phen); Potassium Bisperoxo(1,10-phenanthroline) oxovanadate (V). Grades: ≥98%. CAS No. 171202-16-7. Molecular formula: C12H8N2O5V·K+(H2O)3. Mole weight: 404.3. | |
| BpV(phen) trihydrate | BpV(phen) trihydrate, a insulin-mimetic agent, is a potent protein tyrosine phosphatase (PTP) and PTEN inhibitor with IC50s of 38 nM, 343 nM and 920 nM for PTEN, PTP-? and PTP-1B, respectively. BpV(phen) trihydrate inhibits proliferation of the protozoan parasite Leishmania in vitro. bpV(phen) trihydrate strongly induces the secretion of a large number of chemokines and pro-inflammatory cytokines, and it activates a Th1-type pathway (IL-12, IFN?). BpV(phen) trihydrate can also induce cell apoptosis, and has anti-angiogenic and anti-tumor activity[1][2][3][4][5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Bisperoxovanadium(phen) trihydrate. CAS No. 171202-16-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122818. | |
| bpV(pic) | ?95% V basis. Group: Fluorescence/luminescence spectroscopy. | |
| bpV(pic) | Potent protein phosphotyrosine phosphatase inhibitor. Insulin mimetic. Angiogenesis inhibitor. PTEN inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 148556-27-8. Pack Sizes: 5mg, 25mg. Molecular Formula: K2 [VO(O2)2C6H4NO2] 2H2O. US Biological Life Sciences. | Worldwide |
| bpV(pic) (Dipotassium bisperoxo (picolinoto) oxovanadate (V)) | A bisperoxovanadium compound that acts as a potent protein phosphotyrosine phosphatase (PTP) inhibitor as well as an insulin receptor kinase (IRK) activator. Also a potent PTEN inhibitor (IC50= 31nM). Group: Biochemicals. Alternative Names: Dipotassium bisperoxo (picolinoto) oxovanadate (V). Grades: Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| bpV(pic) potassium hydrate | BpV(pic) is composed of a vanadate molecule coordinated to picolinic acid (2-carboxypyridine) and potassium. It is a bisperoxovanadium (bpV) compound that inhibits several different protein tyrosine phosphatases (PTPs) with IC50 of 31 nM. It is also known to be an insulin mimetic capable of activating the insulin receptor kinase of cultured hepatoma cells and stimulating lipogenesis in adipocytes. BpV(pic) has been shown to activate the insulin receptor kinase (IRK) of cultured hepatoma cells and is also an inhibitor of G6Pase. Synonyms: Bisperoxovanadium(pic). Grades: ≥96%. CAS No. 148556-27-8. Molecular formula: C6H4NO7V·2K·2H2O. Mole weight: 367.3. | |
| Bpy-FOXD | Bpy-FOXD. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,7-Bis[2-(2,2'-bipyridine-6-yl)-1,3,4-oxadiazo-5-yl]-9,9-dimethylfluorene. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1174006-45-1. Molecular formula: C39H26N8O2. Mole weight: 638.68 g/mol. Product ID: ACM1174006451. Alfa Chemistry ISO 9001:2015 Certified. | |
| Bpy-OXD | Bpy-OXD. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,3-Bis[2-(2,2'-bipyridine-6-yl)-1,3,4-oxadiazo-5-yl]benzene. Product Category: Organic Light Emitting Diode (OLED). CAS No. 866117-19-3. Molecular formula: C30H18N8O2. Mole weight: 522.52 g/mol. Product ID: ACM866117193. Alfa Chemistry ISO 9001:2015 Certified. | |
| BPy-TP2 | sublimed. Group: Oled and pled materials. | |
| BPy-TP2 | Electron transport or hole blocking material in OLEDs. Group: Organic light-emitting diode (oled) materials. Alternative Names: 2, 7-Bis(2, 2'-bipyridin-5-yl)triphenylene, 2, 7-Di(2, 2'-bipyridin-5-yl)triphenylene, -(7-[2, 2'-Bipyridin]-5-yl-2-triphenylenyl)-2, 2'-bipyridine. CAS No. 1394813-58-1. Molecular formula: 536.62. |  |
| BQ-123 | BQ-123 is a potent and selective endothelin A (ETA) receptor antagonist with an IC 50 of 7.3 nM and a K i of 25 nM. BQ-123 inhibits endothelin-1-mediated proliferation of human pulmonary artery smooth muscle cells and lowers blood pressure in different rat models of hypertension [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 136553-81-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-12378. | |
| BQ-123 | BQ-123 is a selective endothelin A receptor (ETA) antagonist with IC50 of 7.3 nM. Phase 2. Uses: Endothelin receptor antagonists. Synonyms: BQ123; BQ-123; BQ 123. Cyclo(D-trp-D-asp-pro-D-val-leu). Grades: 98%. CAS No. 136553-81-6. Molecular formula: C31H42N6O7. Mole weight: 610.70. | |
| BQ-123 | ?99%, sodium salt, lyophilized powder. Group: Fluorescence/luminescence spectroscopy. | |
| BQ-123 | BQ-123. Group: Biochemicals. Grades: Purified. CAS No. 136553-81-6. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| BQ-123 Sodium Salt | Potent and selective endothelin receptor A (ETA) antagonist. Suppresses the ET-1-induced decrease of LPL activity. Shows protective effects in ischemic acute renal failure. Neuroprotective. Anti-hypertensive. Inhibits ET-1 receptor binding and blocks Ca2+ mobilization, cellular contraction and MAP kinase activation. Cardiovascular agent. Reduces myocardial infarct size and oxidant injury. Source:Synthetic. Group: Biochemicals. Grades: Highly Purified. CAS No. 136553-81-6. Pack Sizes: 1mg, 5mg. Molecular Formula: C31H42N6O7 Na. US Biological Life Sciences. | Worldwide |
| BQ-123, Sodium Salt - CAS | A highly potent, selective, and competitive ETA (endothelin) receptor antagonist (Ki = 40 nM for ETA versus Ki = 2.5 μM for ETB). Group: Fluorescence/luminescence spectroscopy. | |
| BQ-3020 | BQ-3020. Group: Biochemicals. Grades: Purified. CAS No. 143113-45-5. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| BQ-3020 | BQ-3020 is a potent and selective ETB endothelin receptor agonist (Ki = 0.18 and 970 nM at human ETB and ETA receptors, respectively). Synonyms: endothelin receptor antagonist; Acetyl-(Ala11·15)-Endothelin-1 (6-21). CAS No. 143113-45-5. Molecular formula: C96H140N20O25S. Mole weight: 2006.3. | |
| BQ-610 | A highly selective ETA receptor antagonist (IC?? = 20 nM) that attenuates ET-induced reduction in cardiac output. Group: Fluorescence/luminescence spectroscopy. | |
| BQ-788 | BQ-788 is a potent and selective ETB receptor antagonist with an IC50 of 1.2 nM. Synonyms: BQ-788 free acid; D-Norleucine, N-((cis-2,6-dimethyl-1-piperidinyl)carbonyl)-4-methyl-L-leucyl-1-(methoxycarbonyl)-D-tryptophyl-; N-cis-2,6-Dimethylpiperidinocarbonyl-β-tBu-Ala-D-Trp(1-methoxycarbonyl)-D-Nle-OH. Grades: 95%. CAS No. 173326-37-9. Molecular formula: C34H51N5O7. Mole weight: 641.80. | |
| BQ-788 | ?95%, solid. Group: Fluorescence/luminescence spectroscopy. | |
| BQ-788 | BQ-788 is a potent, selective ETB receptor antagonist with IC 50 of 1.2 nM for inhibition of ET-1 binding to human Girardi heart cells, poorly inhibiting the binding to ETA receptors in human neuroblastoma cell line SK-N-MC cells with IC 50 of 1300 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 173326-37-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-15894A. | |
| BQ 788 sodium salt | BQ 788 sodium salt is a potent, selective ETB receptor antagonist (IC50 = 1.2 nM) without significant activity on ETA receptor (IC50= 1300 nM). Uses: Antihypertensive agents. Synonyms: cis-N-[N-[N-[(2,6-Dimethyl-1-piperidinyl)carbonyl]-4-methyl-L-leucyl]-1-(methoxycarbonyl)-D-tryptophyl]-D-norleucine Monosodium Salt; N-[[(2R,6S)-2,6-Dimethyl-1-piperidinyl]carbonyl]-4-methyl-L-leucyl-1-(methoxycarbonyl)-D-tryptophyl-D-norleucine Monosodium Salt; N-[(cis-2,6-Dimethyl-1-piperidinyl)carbonyl]-4-methyl-L-leucyl-1-(methoxycarbonyl)-D-tryptophyl-D-norleucine Monosodium Salt; (R)-2-((R)-2-((S)-2-((2S,6R)-2,6-Dimethylpiperidine-1-carboxamido)-4,4-dimethylpentanamido)-3-(1-(methoxycarbonyl)-1H-indol-3-yl)propanamido)hexanoic Acid Sodium Salt. Grades: 95%. CAS No. 156161-89-6. Molecular formula: C34H50N5NaO7. Mole weight: 663.78. | |
| BQ-788 sodium salt | BQ-788 sodium salt is a potent and selective ETB receptor antagonist, inhibiting ET-1 binding to ETB receptors with an IC 50 of 1.2 nM in human Girrardi heart cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 156161-89-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-15894. | |
| BQ-788 Sodium Salt | Highly selective ETB-receptor antagonist (IC50=1.2nM). BQ 788 is an endothelin type B (ETB) receptor antagonist and is a potential antidote for the cardiovascular toxicity with hypotension and bradycardia. Group: Biochemicals. Alternative Names: cis-N-[N-[N-[(2,6-Dimethyl-1-piperidinyl)carbonyl]-4-methyl-L-leucyl]-1-(methoxycarbonyl)-D-tryptophyl]-D-norleucine Monosodium Salt; N-[[(2R,6S)-2,6-Dimethyl-1-piperidinyl]carbonyl]-4-methyl-L-leucyl-1-(methoxycarbonyl)-D-tryptophyl-D-norleucine Monosodium Salt; N-[(cis-2,6-Dimethyl-1-piperidinyl)carbonyl]-4-methyl-L-leucyl-1-(methoxycarbonyl)-D-tryptophyl-D-norleucine Monosodium Salt; (R) -2- ( (R) -2- ( (S) -2- ( (2S, 6R) -2, 6-Dimethylpiperidine-1-carboxamido) -4, 4-dimethylpentanamido) -3- (1- (methoxycarbonyl) -1H-indol-3-yl) propanamido) hexanoic Acid Sodium Salt; N-cis-2, 6-Di methyl piperidinocarbonyl-BETA-tBu-Ala-D-Trp (1-methoxycarbonyl) -D-Nle; BQ 788. Grades: Highly Purified. CAS No. 156161-89-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| BQCA | BQCA is a highly selective positive allosteric modulator of the M1 muscarinic acetylcholine receptor (mAChR), as it dose-dependently reduces the concentration of acetylcholine required to activate the M1 receptor. Uses: A highly selective positive allosteric modulator of the m1 muscarinic acetylcholine receptor (machr). Synonyms: 1-(4-Methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid; 1,4-Dihydro-1-[(4-methoxyphenyl)methyl]-4-oxo-3-quinolinecarboxylic Acid. Grades: ≥98%. CAS No. 338747-41-4. Molecular formula: C18H15NO4. Mole weight: 309.32. | |
| BQCA | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BQCA | BQCA a highly selective allosteric modulator of the M1 mAChR. Uses: Scientific research. Group: Signaling pathways. CAS No. 338747-41-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101858. | |
| BQR695 | BQR695 is a potent and selective PI4K inhibitor exhibiting potency against both human PI4KIIIβ and Plasmodium falciparum asexual blood stages (IC50?values of 90?nM and 71 nM, respectively). Uses: Antimalarial. Synonyms: NVP-BQR695; NVP-BQR-695; NVP-BQR 695; BQR695; BQR-695; BQR 695. NVP-BQR695; CS-8070; HY-18748; CS 8070; HY 18748; CS8070; HY18748; 2-[[7-(3,4-dimethoxyphenyl)quinoxalin-2-yl]amino]-N-methylacetamide. Grades: 99%. CAS No. 1513879-21-4. Molecular formula: C19H20N4O3. Mole weight: 352.39. | |
| BQU57 | BQU57, a derivative of RBC8, is a selective GTPase Ral inhibitor relative to the GTPases Ras and RhoA. Synonyms: BQU57; BQU 57; BQU-57. Grades: >98%. CAS No. 1637739-82-2. Molecular formula: C16H13F3N4O. Mole weight: 334.1. | |
| BQU57 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BR | Bromine is a dark reddish-brown fuming liquid with a pungent odor. Denser than water and soluble in water. Hence sinks in water. Toxic by inhalation. Accelerates the burning of combustible material. It is very corrosive to tissue and to metals.;GasVapor; Liquid;FUMING RED-TO-BROWN LIQUID WITH PUNGENT ODOUR.;Dark reddish-brown, fuming liquid with suffocating, irritating fumes.;Dark reddish-brown, fuming liquid with suffocating, irritating fumes. Group: Polymers. Product ID: molecular bromine. Molecular formula: 159.81g/mol. Mole weight: Br2;Br2. BrBr. InChI=1S/Br2/c1-2. GDTBXPJZTBHREO-UHFFFAOYSA-N. | |
| brachyurin | From hepatopancreas of the fiddler crab, Uca pugilator. In peptidase family S1 (trypsin family). Other serine endopeptidases that degrade collagen, but are not listed separately here, include a second endopeptidase from Uca pugilator, digestive enzymes from other decapod crustacea, and an enzyme from the fungus Entomophthora coronata. Group: Enzymes. Synonyms: Uca pugilator collagenolytic proteinase; crab protease I; crab protease II. Enzyme Commission Number: EC 3.4.21.32. CAS No. 848900-32-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4127; brachyurin; EC 3.4.21.32; 848900-32-3; Uca pugilator collagenolytic proteinase; crab protease I; crab protease II. Cat No: EXWM-4127. | |
| Brachyury (Brachyury Homolog, Brachyury Protein, Bry, MGC104817, T, T Protein, TFT), Human, Primer Pair Kit, Positive Control | Brachyury (Brachyury Homolog, Brachyury Protein, Bry, MGC104817, T, T Protein, TFT), Human, Primer Pair Kit, Positive Control. Group: Molecular Biology. Pack Sizes: 1Vial. US Biological Life Sciences. | Worldwide |
| Brachyury (Brachyury Homolog, Brachyury Protein, Bry, MGC104817, T, T Protein, TFT), Human, Primer Pair Kit, Primer | Brachyury (Brachyury Homolog, Brachyury Protein, Bry, MGC104817, T, T Protein, TFT), Human, Primer Pair Kit, Primer. Group: Molecular Biology. Pack Sizes: 1Vial. US Biological Life Sciences. | Worldwide |
| Braco-19 | Braco-19 is a potent telomerase/telomere inhibitor, preventing the capping and catalytic action of telomerase. Braco-19 acts as G-quadruplex (GQ) binding ligand, stabilizing G-quadruplexes formation at the 3V telomeric DNA overhang and produce rapid senescence or selective cell death. Braco-19 is also a HAdV virus replication inhibitor[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 351351-75-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15523. | |
| BRACO19 hydrochloride | ?96% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Braco-19 trihydrochloride | Braco-19 trihydrochloride is a potent telomerase/telomere inhibitor, preventing the capping and catalytic action of telomerase. Braco-19 acts as G-quadruplex (GQ) binding ligand, stabilizing G-quadruplexes formation at the 3V telomeric DNA overhang and produce rapid senescence or selective cell death. Braco-19 is also a HAdV virus replication inhibitor[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1177798-88-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15523A. | |
| BRACO 19 trihydrochloride | BRACO 19 trihydrochloride is a telomerase inhibitor (IC50 = 115 nM) that suppresses the expression of human telomerase reverse transcriptase (hTERT) and induces cellular senescence. BRACO 19 was shown to inhibit growth of uterine cancer cells in vitro and growth of uterine tumor xenografts in mice. Synonyms: N,N'-[9[[4-(Dimethylamino)phenyl]amino]-3,6-acridinediyl]bis-1-pyrrolidinepropanamide trihydrochloride. Grades: ≥95% by HPLC. CAS No. 1177798-88-7. Molecular formula: C35H43N7O2.3HCl. Mole weight: 703.14. | |
| Bractoppin | Bractoppin is a potent and selective agent-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem(t) BRCT domain (binding IC50: 74 nM). Bractoppin diminishes BRCA1 recruitment to DNA breaks, in turn suppressing damage-induced G2 arrest and assembly of the recombinase, RAD51. Bractoppin preferentially inhibits BRCA1 tBRCT-dependent steps in the DNA damage response[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2290527-07-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126020. | |
| Bradanicline | Bradanicline acts as a partial agonist at the α7 subtype of the neural nicotinic acetylcholine receptors. It showed cognitive enhancing effects in animal studies, and was used as a potential treatment for schizophrenia and attention deficit disorder. It was used for Alzheimer's disease and cognitive impairment, but was discontinued. It was being developed by Targacept and was in phase II trials, but now it is terminated. Uses: Bradanicline was used as a potential treatment for schizophrenia and attention deficit disorder. it was used for alzheimer's disease and cognitive impairment. Synonyms: TC-5619; TC 5619; TC5619; N-[(2S,3R)-2-(pyridin-3-ylmethyl)-1-azabicyclo[2.2.2]octan-3-yl]-1-benzofuran-2-carboxamide;TC-5619-023;TC5619-023. Grades: 98%. CAS No. 639489-84-2. Molecular formula: C22H23N3O2. Mole weight: 361.44. | |
| Bradanicline | Bradanicline is a highly selective α7 nicotinic acetylcholine receptor (nAChR) agonist (humanα7 nAChR: EC 50 =17 nM; K i = 1.4 nM). Bradanicline is used for the research of cognitive disorders [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TC-5619. CAS No. 639489-84-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18060. | |
| Bradanicline hydrochloride | Bradanicline hydrochloride is Alpha-7 Nicotinic Receptor Agonist. It showed cognitive enhancing effects in animal studies, and was being developed as a potential treatment for schizophrenia and attention deficit disorder. It was discontinued for Alzheimer's disease and cognitive impairment in schizophrenia in late 2013. It was also discontinued for ADHD, and no longer seems to be being developed. Uses: Bradanicline hydrochloride was being developed as a potential treatment for schizophrenia and attention deficit disorder. Synonyms: TC-5619;TC5619;TC-5619-023;TC5619-023;N-((2S,3R)-2-(pyridin-3-ylmethyl)quinuclidin-3-yl)benzofuran-2-carboxamide hydrochloride. Grades: >98%. CAS No. 1111941-90-2. Molecular formula: C22H24ClN3O2. Mole weight: 397.90. | |
| Bradykinin | Bradykinin is an effective endothelium-dependent vasodilator that can lower blood pressure. Bradykinin can induce contraction of bronchial and intestinal non-vascular smooth muscle, increase vascular permeability, and participate in the mechanism of pain [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Peptides. CAS No. 58-82-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0206. | |
| Bradykinin | Bradykinin is a nonapeptide messenger produced from kallidin in the blood. Bradykinin has the selectivity for B2 over B1 receptors. It exhibits hypotensive and anti-inflammatory properties. Uses: Hypotensive agent. Synonyms: H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH; L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl-L-arginine; L-Bradykinin; Kallidin I; Callidin I; Kallidin 9. Grades: ≥95%. CAS No. 58-82-2. Molecular formula: C50H73N15O11. Mole weight: 1060.21. | |
| Bradykinin 1-3 | Bradykinin 1-3, a 3-amino acid residue peptide fragment of Bradykinin, is an amino-truncated Bradykinin cleaved by Prolyl endopeptidase. Synonyms: Bradykinin (1-3); Arginyl-prolyl-proline; arginylprolylproline; L-Arginyl-L-prolyl-L-proline; H-RPP-OH. Grades: 95%. CAS No. 23815-91-0. Molecular formula: C16H28N6O4. Mole weight: 368.43. | |
| Bradykinin(1-3) | Bradykinin(1-3). Uses: Designed for use in research and industrial production. Additional or Alternative Names: H-ARG-PRO-PRO-OH SULFATE;H-ARG-PRO-PRO-OH SULFATE SALT;H-Arg-Pro-Pro-OH;arginyl-prolyl-proline;L-Proline, 1-(1-L-arginyl-L-prolyl)-. Product Category: Heterocyclic Organic Compound. CAS No. 23815-91-0. Molecular formula: C16H28N6O4. Mole weight: 466.51. Product ID: ACM23815910. Alfa Chemistry ISO 9001:2015 Certified. | |
| Bradykinin (1-5) | Bradykinin (1-5) is a major stable metabolite of Bradykinin, formed by the proteolytic action of angiotensin-converting enzyme (ACE). Uses: Scientific research. Group: Peptides. CAS No. 23815-89-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P1488. | |
| Bradykinin 1-5 | Bradykinin 1-5 is the main stable metabolite of Bradykinin and is formed by proteolysis of angiotensin-converting enzyme (ACE). Synonyms: H-RPPGF-OH; L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanine; Bradykinin (1-5); Bradykinin Fragment 1-5; 1-5-Bradykinin (9Cl); N-[2-({[1-(Arginylprolyl)pyrrolidin-2-yl](hydroxy)methylidene}amino)-1-hydroxyethylidene]phenylalanine. Grades: ≥95%. CAS No. 23815-89-6. Molecular formula: C27H40N8O6. Mole weight: 572.66. | |
| Bradykinin 1-6 | Bradykinin 1-6, a stable metabolite of Bradykinin, is an amino-truncated Bradykinin peptide cleaved by carboxypeptidase Y (CPY). Synonyms: H-Arg-Pro-Pro-Gly-Phe-Ser-OH; L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-serine; (S)-2-((S)-2-(2-((S)-1-((S)-1-((S)-2-amino-5-guanidinopentanoyl)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamido)acetamido)-3-phenylpropanamido)-3-hydroxypropanoic acid; Bradykinin (1-6). Grades: 95%. CAS No. 23815-88-5. Molecular formula: C30H45N9O8. Mole weight: 659.73. | |
| Bradykinin (2-9) | Bradykinin (2-9) is an amino-truncated Bradykinin peptide. Bradykinin (2-9) is a metabolite of Bradykinin, cleaved by Aminopeptidase P. Uses: Scientific research. Group: Peptides. Alternative Names: Des-Arg1-bradykinin. CAS No. 16875-11-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1490. | |
| Bradykinin 2-9 | Bradykinin 2-9, a metabolite of Bradykinin, is an amino-truncated Bradykinin peptide cleaved by Aminopeptidase P. Synonyms: Des-Arg1-bradykinin; H-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH; L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl-L-arginine; Bradykinin fragment 2-9; 2-9-Bradykinin. Grades: ≥95%. CAS No. 16875-11-9. Molecular formula: C44H61N11O10. Mole weight: 904.02. | |
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